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Addiction Literature's Past and Present
by Mark RonanAddiction Literature's Past and Present aims to realign consideration of addiction as a transhistorical and transcultural aspect of the human condition. This book illuminates the premodern roots of the linguistic and narrative materials of addiction discourse and argues for Addiction Literature to be considered as a distinct literary phenomenon, with a history stretching back to Antiquity. Addiction, as it is understood in this book, exists at the intersection between appetite, habit and impaired personal behavioural agency. This book begins by exploring the ways in which we articulate the experience (both lived and observed) of addiction today, uncovering a core set of conceptual components and discursive tropes which are commonly associated with modern understandings of the phenomenon. Having established a common set of tropes and features which distinguish modern Addiction Literature as a distinct literary mode, it then considers premodern texts through this lens, revealing similar patterns of conception and convention in a broad range of historical periods and literary genres from Aesop to Shakespeare.
Addiction Medicine: A Case and Evidence-Based Guide (Psychiatry Update #2)
by Jonathan D. Avery David HankinsThis book provides an accessible, up-to-date understanding of how to treat patients with substance and non-substance-related addiction. It covers all the typical substance and non-substance use disorders and presents evidence in a case-based format.Concise and comprehensive, opening chapters relay a preliminary assessment of addiction disorders and their neurobiology. Subsequent chapters then offer specific treatment options, challenges, and cases relating to the abuse of distinct substances. The substances mentioned earlier include alcohol, opioids, stimulants, hallucinogens, and sedatives. Additionally, one chapter covers the unique issues associated with treating behavioral addictions, such as sex and gambling. Each chapter will outline cases in a fashion that will optimize the reader's experience. In closing, the book examines co-occurring substance use disorders and mental illness.An invaluable addition to the Psychiatry Update Series, Addiction Medicine is an essential reference for mental health clinicians, as well as primary care and family medicine clinicians.
Addiction Medicine: Science and Practice
by Bankole A. JohnsonThe spectrum of addiction disorders presents practitioners with numerous challenges--among them the widening gap between a growing evidence base and the translation of this knowledge into treatment outcomes. Addiction Medicine addresses this disconnect, clearly explaining the role of brain function in drug taking and other habit-forming behaviors, and applying this biobehavioral framework to the delivery of evidence-based treatment. Its state-of-the-art coverage provides clinically relevant details on not only traditional sources of addiction such as cocaine, opiates, and alcohol, but also more recently recognized substances of abuse (e.g., steroids, inhalants) as well as behavioral addictions (e.g., binge eating, compulsive gambling, hoarding). Current behavioral and medical therapies are discussed in depth, and the book's close attention to social context gives readers an added lens for personalizing treatment. An international panel of expert contributors offers the most up-to-date information on: Diagnosis and classification Neurobiological and molecular theories of addiction Behavioral concepts of addiction Clinical aspects of addiction to a wide range of substances, including opiates, stimulants, sedatives, hallucinogens, alcohol, nicotine, and caffeine Science-based treatment options: pharmacotherapy, pharmacogenetics, potential vaccines, brief and compliance-enhancing interventions, cognitive behavioral treatment, behavioral management, and other psychosocial interventions Behavioral addictions--including compulsive eating, Internet messaging, and hypersexuality--and their treatment Addiction in specific populations, including adolescents, the elderly, pregnant women, and health care professionals Legal, disability, and rehabilitation issues At once comprehensive and integrative, Addiction Medicine is an essential text and a practice-expanding tool for psychiatrists, health psychologists, pharmacologists, social workers, drug counselors, trainees, and general physicians/family practitioners.
Addiction Neuroethics
by Wayne Hall Adrian CarterAddiction is a significant health and social problem and one of the largest preventable causes of disease globally. Neuroscience promises to revolutionise our ability to treat addiction, lead to recognition of addiction as a 'real' disorder in need of medical treatment and thereby reduce stigma and discrimination. However, neuroscience raises numerous social and ethical challenges: * If addicted individuals are suffering from a brain disease that drives them to drug use, should we mandate treatment? * Does addiction impair an individual's ability to consent to research or treatment? * How will neuroscience affect social policies towards drug use? Addiction Neuroethics addresses these challenges by examining ethical implications of emerging neurobiological treatments, including: novel psychopharmacology, neurosurgery, drug vaccines to prevent relapse, and genetic screening to identify individuals who are vulnerable to addiction. Essential reading for academics, clinicians, researchers and policy-makers in the fields of addiction, mental health and public policy.
The Addiction of Mary Todd Lincoln
by Anne E. BeidlerMary Todd Lincoln, wife of the president we have immortalized, has always been difficult for us to understand. She could appear poised and brilliant one moment yet rude and ugly the next. Sometimes competent and strong, able to entertain dignitaries from around the world, at other times she appeared dependent and weak. At times she seemed utterly beside herself with sobbing and screaming. Historians have mostly avoided saying very much about Mary Todd Lincoln except in reference to her husband, Abraham. To many it would seem that Mary Todd Lincoln is still an embarrassment in the tragic story of her martyred husband. But Mary Todd Lincoln lived her own tragic story even before Abraham was murdered. She was an addict, addicted to the opiates she needed for her migraine headaches. Seeing Mary Todd Lincoln as an addict helps us understand her and give her the compassion and admiration she deserves. In her time there had been no courageous First Lady like Betty Ford to help people understand the power of addiction. There was no treatment center. In Mary Todd Lincoln's time there were many addicts at all levels of society, as there are now, but it was a more socially acceptable condition for men to have than for women. More importantly, addiction was not very well understood, and it was often mistreated. Because Mary Todd Lincoln's only surviving son, Robert Lincoln, made a great effort to protect his mother and his family from journalists and historians, he intentionally destroyed most of Mary Todd Lincoln's medical records and many of her letters. What he could not destroy, however, is the record of Mary Todd Lincoln's pain and the record of how she behaved while living with this pain. In The Addiction of Mary Todd Lincoln, we can see clearly, for the first time, what Mary Todd Lincoln had to live with and the courage it took for her to carry on.
Addiction Potential of Abused Drugs and Drug Classes
by Barry StimmelIncrease your awareness of the relative addiction liabilities of various drugs and drug classes that are commonly abused. A timely and masterful new book, Addiction Potential of Abused Drugs and Drug Classes clarifies, in contemporary terminology, the state of addiction liability of cocaine, opiates, alcohol, sedative-hypnotics, nicotine, anxiolytics, marijuana, inhalants and anesthetics, and PCP and hallucinogens--the nine drugs that are most abused today. Authorities combine their research expertise with the available scientific literature to evaluate those factors which contribute to the addictive qualities of drugs. Specific chapters highlight the positive and negative reinforcement qualities that make drugs rewarding, focus on the two major subtypes of alcoholics, and cover the neuroanatomical and neurochemical bases of psychological dependence, the greatest contributing factor to drug addiction. An essential new resource for scientists, clinicians, and administrators, Addiction Potential of Abused Drugs and Drug Classes also highlights those areas where more work is needed in order to understand how individual drugs affect the processes of dependence, tolerance, and addiction, so that adequate treatment of these disorders can be discovered.The book was written for teachers and researchers in the chemical dependency field, to provide an up-to-date review of the literature. In addition, physicians, nurses, and pharmacists will find the book to be valuable as an update on the relative addiction strengths of abused drugs. Finally, treatment counselors and professionals with some knowledge of physiology and pharmacology will be interested in the book because of its relevance to the clinical treatment of chemically-dependent patients.
Addiction Recovery Management: Theory, Research and Practice (Current Clinical Psychiatry)
by John F. Kelly William L. WhiteAddiction Recovery Management: Theory, Research, and Practice is the first book on the recovery management approach to addiction treatment and post-treatment support services. Distinctive in combining theory, research, and practice within the same text, this ground-breaking title includes authors who are the major theoreticians, researchers, systems administrators, clinicians and recovery advocates who have developed the model. State-of-the art and the definitive text on the topic, Addiction Recovery Management: Theory, Research, and Practice is mandatory reading for clinicians and all professionals who work with patients in recovery or who are interested in the field.
Addiction Research and Evaluation: Addressing Key Challenges for Policy and Practice (Advances in Mental Health and Addiction)
by Catherine ComiskeyAccording to the United Nations Office of Drugs and Crime, around 284 million people aged between 15 and 64 years used drugs in the year 2020. In addition, it is estimated that over 11 million people were injecting drugs and half of these were living with hepatitis C. Young people are using more drugs than previously, and numbers have increased over the past decade. While numbers are estimated at a global level, there remains little evidence for practitioners and policy makers on key questions, such as how many people are using drugs that are hidden and haven’t contacted services. Questions include the challenging topics of providing safe injecting spaces and drug consumption rooms. As populations age in some regions, questions arise on the nature of substance use among older people. Countries with younger populations are concerned about estimates on the numbers of children potentially impacted by parental substance use and how to engage with them. Awareness of trauma informed services is increasing and questions arise on the impact of domestic abuse or adverse childhood experiences on people who use drugs and their families. Globally, there is a growing concern on how to inform the debate on cannabis policies and how to assess if the chosen policy will be acceptable to the general population. The aim of this book is to provide researchers, service providers and policy makers with a step-by-step guide to robust methodologies and illustrative case studies to address these challenges. The objective of each chapter is to answer a key question, provide a summary of the background evidence, demonstrate through a series of logical steps how to obtain national or local evidence, and finally illustrate the process with detailed, real life case studies. As addiction is encountered across a wide range of professions and civil society organizations, this book will be an essential textbook for graduate students of medicine, nursing public health, addiction, psychology and health and social care professions. It will be a guiding reference book for international, national and local commissioners and providers of related policies and services. At a local level the step-by-step case studies will provide an easy to follow framework for those wishing to apply the methods to benefit and improve their own practice, service or policy.
The Addiction Solution: Treating Our Dependence on Opioids and Other Drugs
by Lloyd SedererA groundbreaking examination of addiction from a psychiatrist and public health doctor, offering practical, proven solutions for individuals, families, and communities dealing with substance use and abuse.Written with warmth, accessibility, and vast authority, The Addiction Solution is a practical guide through the world of drug use and abuse and addiction treatment. Here, Lloyd I. Sederer, MD, brings together scientific and clinical knowledge, policy suggestions, and case studies to describe our current drug crisis and establish a clear path forward to recovery and health. In a time when so many people are affected by the addiction epidemic, when 142 people die of overdoses every day in the United States, principally from opioids, Sederer’s decades of wisdom and clinical experience are needed more than ever before. With a timely focus on opioids, Sederer takes us through the proven essentials of addiction treatment and explains why so many of our current policies, like the lingering remnants of the War on Drugs, fail to help drug users, their families, and their wider communities. He identifies a key insight, often overlooked in popular and professional writing about addiction and its treatment: namely, that people who use drugs do so to meet specific needs, and that drugs may be the best solution those people currently have. Writing with generosity and empathy about the many Americans who use illicit and prescribed substances, Sederer lays out specific, evidence-based, researched solutions to the prevention and problems of drug use, including exercise, medications, therapy, recovery programs, and community services. In this challenging time, The Addiction Solution provides practical help, comfort, and hope.
The Addictive Behaviors
by Howard J Shaffer Barry StimmelThoroughly examines the natural history and social etiology of addictive behaviors.
Addictive Disorders in Arctic Climates: Theory, Research, and Practice at the Novosibirsk Institute
by Bernard SegalDiscover fresh perspectives on alcoholism treatment and research with this enlightening new book describing the work of researchers at the Novosibirsk Medical Institute, USSR. By using specific examples of their studies in Siberia, the reserachers offer an innovative approach to the treatment of addictive disorders in general. Instead of focusing on the drinking behavior itself, the treatment focuses on the relation of the problem to the interaction of economic, social, and psychological factors. To address the question of whether alcoholics should all be treated in the same way, or if alcholism treatment should be more individualized in approach, chapters are devoted to the differences between alcoholism in women, adolescents, and alchoholics who are afflicted with “rapid development of alcholism syndrome.” The research examples in Addictive Disorders in Arctic Climates benefits professionals involved in the treatment of alcholism by introducing new perspectives and broadening contemporary research.
Additive Manufacturing for Biomedical Applications: Recent Trends and Challenges (Biomedical Materials for Multi-functional Applications)
by Anurag Dixit Anil Kumar Dayanidhi K. PathakNew fabrication techniques and biomaterials have advanced significantly as attention toward healthcare innovations in recent decades has increased. This book provides a comprehensive overview of the application of additive manufacturing for biomedical devices. The book focuses on the use of biomaterial for hard and soft tissue engineering. These materials can imitate the mechanical, structural, and biological characteristics of the parent tissue, repairing or replacing its functioning. It provides details on the use of various biomaterials for different biomedical applications. It highlights the present trends and potential of various techniques and materials for various applications. The chapters in this book written by eminent experts highlight recent developments in additive manufacturing for biological mimicking and surgical planning. It discusses latest advances in various 3D printing technologies in the fabrication of biomedical devices for orthopaedic and cardiovascular applications, along with rising trends in designing and creating tissue replacement substitute simulants. This book can serve as a fundamental textbook for research in additive manufacturing, fabrication of implants or scaffolds and medical device development, biomaterials, tissue engineering, and biomedical engineering. This book can be a valuable resource for mechanical and biomedical engineers, academicians, healthcare researchers, and professionals interested in tissue engineering.
Additive Manufacturing in Multidisciplinary Cooperation and Production (Springer Tracts in Additive Manufacturing)
by Igor Drstvensek Snehashis Pal Nataša Ihan HrenThis book publishes the latest findings and ideas in the field of additive manufacturing presented by authors from prominent institutions around the world at the iCAT 2023 conference. The authors address various technological and medical aspects, ranging from materials science to the specific behaviour of the technology under different working conditions. The book is divided into four sections, three of which are dedicated to the purely technological aspects of additive manufacturing, covering metal processes, polymer processes and simulation. The fourth part of the book is dedicated to the medical applications of additive manufacturing, covering areas ranging from orthopaedic surgeries to materials used in medical AM.Overall, the book provides insight into the current state of the science and applications of additive manufacturing.
Additive Manufacturing in Pharmaceuticals
by Subham BanerjeeThis book presents the different 3D/4D printing technological applications of Additive Manufacturing (AM) in Pharmaceutical Sciences. The initial chapter provides the historical perspective and current scenario of AM in pharmaceuticals. The book further discusses about different 3D printing platform technologies such as FDM, SLA, SLS, SSE, Ink-jet & binder jet principles & applications in developing advanced drug delivery systems. It also covers the methodology, materials for AM and important parameters associated with these platform technologies. The book highlights the progress and practical applications of 4D-printing technology in healthcare & pharmaceuticals fraternity as well including the essence of bioprinting in pharmaceuticals. Finally, the book reviews the regulatory guidelines, perspectives, and integration of Artificial Intelligence (AI)/Machine learning (ML) in pharmaceutical AM. This book is indeed a valuable resource for students, researchers/scholars, young start-ups/entrepreneurs, and pharmaceutical professionals by providing thorough detailing about AM in Pharmaceuticals.
Additive Manufacturing of Polymers for Tissue Engineering: Fundamentals, Applications, and Future Advancements (Sustainable Manufacturing Technologies)
by Atul Babbar Ranvijay Kumar Vikas Dhawan Nishant Ranjan Ankit SharmaApplication of additive manufacturing and tissue engineering in the fields of science and technology enables the manufacturing of biocompatible, customized, reliable, and cost-effective parts, restoring the functionality of a failed human body part. This book offers a platform for recent breakthroughs in additive manufacturing related to biomedical applications. This book highlights some of the top innovations and advances in additive manufacturing and processing technologies that are the future of the manufacturing industry while also presenting current challenges and opportunities regarding the choice of material. This book includes areas of applications such as surgical guides, tissue regeneration, artificial scaffolds, implants, and drug delivery and release. Throughout the book, an emphasis is placed on rapid tooling for engineering applications. Additive Manufacturing of Polymers for Tissue Engineering: Fundamentals, Applications, and Future Advancements acts as a first-hand source of information for academic scholars and commercial manufacturers as they make strategic manufacturing and development plans.
Additive Manufacturing Processes in Biomedical Engineering: Advanced Fabrication Methods and Rapid Tooling Techniques (Sustainable Manufacturing Technologies)
by Atul Babbar Ankit Sharma Vivek Jain Dheeraj GuptaThis book covers innovative breakthroughs in additive manufacturing processes used for biomedical engineering. More and more, 3D printing is selected over traditional manufacturing processes, especially for complex designs, because of the many advantages such as fewer restrictions, better production cost savings, higher quality control, and accuracy. Current challenges and opportunities regarding material, design, cost savings, and efficiency are covered along with an outline of the most recent fabrication methods used for converting biomaterials into integrated structures that can fit best in anatomy while still obtaining the necessary architecture, mechanical reliability, biocompatibility, and anti-bacterial characteristics needed. Additional chapters will also focus on selected areas of applications such as bionics, affordable prostheses, implants, medical devices, rapid tooling, and drug delivery. Additive Manufacturing Processes in Biomedical Engineering: Advanced Fabrication Methods and Rapid Tooling Techniques acts as a first-hand reference for commercial manufacturing organizations which are mimicking tissue organs by using additive manufacturing techniques. By capturing the current trends of today’s manufacturing practices this book becomes a one-stop resource for manufacturing professionals, engineers in related disciplines, and academic researchers.
ADDRESSING FOODBORNE THREATS TO HEALTH: Policies, Practices, and Global Coordination
by Institute of Medicine of the National AcademiesThe National Academies Press (NAP)--publisher for the National Academies--publishes more than 200 books a year offering the most authoritative views, definitive information, and groundbreaking recommendations on a wide range of topics in science, engineering, and health. Our books are unique in that they are authored by the nation's leading experts in every scientific field.
Addressing The Nation's Changing Needs For Biomedical And Behavioral Scientists
by National Research CouncilAs biomedical and behavioral research progresses into new areas, the number of scientists active in various fields rises and falls, and the health needs of the U.S. population evolve, it is important to ensure that the preparation of future investigators reflects these changes. This book addresses these topics by considering questions such as the following: What is the current supply of biomedical and behavioral scientists? How is future demand for scientists likely to be affected by factors such as advances in research, trends in the employment of scientists, future research funding, and changes in health care delivery? What are the best ways to prepare prospective investigators to meet future needs in scientific research?In the course of addressing these questions, this volume examines the number of investigators trained every year, patterns of hiring by universities and industry, and the age of the scientific workforce in different fields, and makes recommendations for the number of scientists that should be trained in the years ahead.This book also considers the diversity of the research workforce and the importance of providing prospective scientists with the skills to successfully collaborate with investigators in related fields, and offers suggestions for how government and universities should structure their research training programs differently in the future.
ADDRESSING THE BARRIERS TO PEDIATRIC DRUG DEVELOPMENT: Workshop Summary
by Institute of Medicine of the National AcademiesDecades of research have demonstrated that children do not respond to medications in the same way as adults. Differences between children and adults in the overall response to medications are due to profound anatomical, physiological, and developmental differences. Although few would argue that children should receive medications that have not been adequately tested for safety and efficacy, the majority of drugs prescribed for children--50 to 75 percent--have not been tested in pediatric populations. Without adequate data from such testing, prescribing drugs appropriately becomes challenging for clinicians treating children, from infancy through adolescence. Addressing the Barriers to Pediatric Drug Development is the summary of a workshop, held in Washington, D.C. on June 13, 2006, that was organized to identify barriers to the development and testing of drugs for pediatric populations, as well as ways in which the system can be improved to facilitate better treatments for children.
Addressing the Threat of Drug-Resistant Tuberculosis: A Realistic Assessment of the Challenge - Workshop Summary
by Institute of Medicine of the National AcademiesTuberculosis is one of the leading causes of death in the world today, with 4,500 people dying from the disease every day. Many cases of TB can be cured by available antibiotics, but some TB is resistant to multiple drugs--a major and growing threat worldwide. The Institute of Medicine's Forum on Drug Discovery, Development, and Translation hosted a workshop on November 5, 2008, to address the mounting concern of drug-resistant TB. The session brought together a wide range of international experts to discuss what is known and not known about this growing threat, and to explore possible solutions.
Addressing Unhealthy Alcohol Use in Primary Care
by Richard SaitzWhile there is a wealth of published information on addiction medicine, the psychological aspects of alcohol abuse, and behavioral medicine with regard to addiction, virtually none of these resources were written with the primary care provider in mind. Addressing Unhealthy Alcohol Use in Primary Care is a resource for primary care clinicians who are confronted by patients with these problems daily, and who wish to successfully address these issues in their practice. It would focus on the literature and science relevant to primary care practice and cover the range of interventions appropriate for this setting. Topics include assessment, brief counseling interventions, pharmacotherapy, referrals to both specialty care and Alcoholics Anonymous (and other self-help programs), psychiatric co-morbidity and other drug use, and other information specific to the needs of the primary care provider.
Addressing Violence, Abuse and Oppression: Debates and Challenges
by Barbara Fawcett Fran WaughEveryone working in health and social care is at one point or another confronted by violent behaviour and its consequences. Addressing Violence, Abuse and Oppression provides a broad overview of violence in relation to a range of groups and areas that involve human service professionals. Adopting an international perspective, this book looks at the ways in which violence, abuse and oppression can be clearly associated with power imbalances which are often gendered and which are covertly or overtly manifested at a range of levels including the interpersonal as well as the organizational and the political. It explores debates and challenges with regard to theoretical orientations, policy frameworks and how power imbalances intersect with a range of influencing factors including gender, poverty, indigenous/ethnic issues, class and sexuality. Examining the implications for human service professionals, each chapter of Addressing Violence, Abuse and Oppression provides an historical overview, explores theoretical perspectives, examines specific policy and practice context, appraises the contribution from research and assesses the impact for individuals and groups.
Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology #807)
by Richard O. Snyder Philippe MoullierToday, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding -- or at least an appreciation of -- the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.
Adenocarcinoma of the Esophagogastric Junction: From Barrett's Esophagus to Cancer
by Simone Giacopuzzi Andrea Zanoni Giovanni ManzoniThis book offers up-to-date and comprehensive coverage of the diagnosis and therapy of adenocarcinoma of the esophagogastric junction (EGJ). As is appropriate in the era of multidisciplinary and multimodal treatment, the contributions of all the various specialists involved cooperatively in the treatment of EGJ cancer are thoroughly described. Detailed attention is also paid to the significance of preneoplastic lesions, such as Barrett esophagus. The final part of the book represents a surgical atlas documenting the techniques used in the EGJ region, with superb color images and stepwise description of procedures. Against the background of the rapidly increasing incidence in EGJ cancer, especially evident in Western countries, there is a need for greater uniformity in management strategies, which currently vary significantly across the world. This book provides appropriate guidance that will assist all practitioners involved in the diagnosis and treatment of EGJ cancers, including surgeons, oncologists, and radiotherapists.
Adenocarcinoma of the Esophagogastric Junction: Adenocarcinoma Of The Esophagogastric Junction (Recent Results in Cancer Research #182)
by Paul M. SchneiderAmong malignant tumors, adenocarcinomas of the esophagogastric junction show the highest increase in incidence over the past three decades in Western industrialized countries. This special volume, with contributions from experts in the field, covers all aspects of the disease. Etiology, pathogenesis, classification, and clinical staging are discussed, and there is special emphasis on state of the art treatment techniques. The latter range from endoscopic mucosal resections or limited surgical resections for early cancers to multimodality treatment options for locally advanced tumors. Emerging quality issues in surgical management are addressed. Detailed attention is also paid to other important recent developments, including molecular response prediction, early metabolic response evaluation by PET and PET-CT, the diagnosis of micrometastases, and the use of sentinel node technology. This volume will be of interest to all clinicians concerned with the diagnosis and management of this malignancy.