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Bioinformatics: Tools and Applications (Methods in Molecular Biology #Vol. 406)

by David Edwards Jason Stajich David Hansen

Bioinformatics is a relatively new field of research. It evolved from the requirement to process, characterize, and apply the information being produced by DNA sequencing technology. The production of DNA sequence data continues to grow exponentially. At the same time, improved bioinformatics such as faster DNA sequence search methods have been combined with increasingly powerful computer systems to process this information. Methods are being developed for the ever more detailed quantification of gene expression, providing an insight into the function of the newly discovered genes, while molecular genetic tools provide a link between these genes and heritable traits. Genetic tests are now available to determine the likelihood of suffering specific ailments and can predict how plant cultivars may respond to the environment. The steps in the translation of the genetic blueprint to the observed phenotype is being increasingly understood through proteome, metabolome and phenome analysis, all underpinned by advances in bioinformatics. Bioinformatics is becoming increasingly central to the study of biology, and a day at a computer can often save a year or more in the laboratory. The volume is intended for graduate-level biology students as well as researchers who wish to gain a better understanding of applied bioinformatics and who wish to use bioinformatics technologies to assist in their research. The volume would also be of value to bioinformatics developers, particularly those from a computing background, who would like to understand the application of computational tools for biological research. Each chapter would include a comprehensive introduction giving an overview of the fundamentals, aimed at introducing graduate students and researchers from diverse backgrounds to the field and bring them up-to-date on the current state of knowledge. To accommodate the broad range of topics in applied bioinformatics, chapters have been grouped into themes: gene and genome analysis, molecular genetic analysis, gene expression analysis, protein and proteome analysis, metabolome analysis, phenome data analysis, literature mining and bioinformatics tool development. Each chapter and theme provides an introduction to the biology behind the data describes the requirements for data processing and details some of the methods applied to the data to enhance biological understanding.

Bioinformatics: Volume I: Data, Sequence Analysis and Evolution (Methods in Molecular Biology #452)

by Jonathan M. Keith

In this book, leading researchers in the field of Bioinformatics provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems. Over 80 authors from around the globe contribute to the two volumes, including many leading experts in their respective subjects. They encompass topics from across the diverse field of bioinformatics through its broad scope, combining to provide an inter-disciplinary collaboration involving biologists, biochemists, physicists, mathematicians, statisticians and computer scientists.

Bioinformatics: Volume I: Data, Sequence Analysis, and Evolution (Methods in Molecular Biology #1525)

by Jonathan M. Keith

In Bioinformatics, leading researchers provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems. Volume II: Structure, Function and Applications contains methods pertinent to the prediction of protein and RNA structures and the analysis and classification of structures, methods for inferring the function of previously identified genomic elements, chiefly protein-coding genes, medical applications in diagnostics and drug discovery, and "meta-methods" for developers of bioinformatics algorithms. Over 80 authors from around the globe have contributed to the two volumes.

Bioinformatics: Volume II: Structure, Function, and Applications (Methods in Molecular Biology #1526)

by Jonathan M. Keith

In Bioinformatics, leading researchers provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems. Volume II: Structure, Function and Applications contains methods pertinent to the prediction of protein and RNA structures and the analysis and classification of structures, methods for inferring the function of previously identified genomic elements, chiefly protein-coding genes, medical applications in diagnostics and drug discovery, and "meta-methods" for developers of bioinformatics algorithms. Over 80 authors from around the globe have contributed to the two volumes.

Bioinformatik

by Rainer Merkl

Die zweite Auflage dieses erfolgreichen Lehrbuchs ist vollständig überarbeitet und in großen Teilen erweitert. Insbesondere wurde die Behandlung der Genomdatenanalyse deutlich vertieft und es wurden Kapitel über maschinelles Lernen, bayessche Netzwerke sowie Protein- und Enzymdesigns und über die Auswertung von Microarrays eingeführt. Außerdem steht dem Leser jetzt eine attraktive Webseite mit Zusatzmaterial und Fragen zum Stoff zur Verfügung. Webseite mit Zusatzmaterial und Fragen: WWW. WILEY-VCH. DE/HOME/BIOINFORMATIK

Bioinformatik Interaktiv

by Stephan Waack Rainer Merkl

Die zweite Auflage dieses erfolgreichen Lehrbuchs ist vollständig überarbeitet und in großen Teilen erweitert. Insbesondere wurde die Behandlung der Genomdatenanalyse deutlich vertieft und es wurden Kapitel über maschinelles Lernen, bayessche Netzwerke sowie Protein- und Enzymdesigns und über die Auswertung von Microarrays eingeführt. Außerdem steht dem Leser jetzt eine attraktive Webseite mit Zusatzmaterial und Fragen zum Stoff zur Verfügung. Webseite mit Zusatzmaterial und Fragen: WWW.WILEY-VCH.DE/HOME/BIOINFORMATIK

Bioinformatik am Beispiel des SARS-CoV2 Virus und der Covid19 Pandemie (essentials)

by Thomas Dandekar Meik Kunz

In diesem Buch werden dem Leser einführend zentrale Ansätze der Bioinformatik entsprechend dem Fluss der genetischen Information von der Sequenzanalyse vom Virusgenom und seinen Proteinen über die Strukturvorhersage hin zu komplexeren Analysen (Interaktionen mit dem Wirt, Immunsystem) vorgestellt. Proteinnetzwerke, Metabolismus und Signalkaskaden erlauben dem Virus, eine hochgefährliche Infektion im Menschen zu erzeugen. Die Bioinformatik leistet wertvolle Hilfestellung bei der Diagnose, der Suche nach Behandlungsmöglichkeiten und vor allem bei der Herstellung von Impfstoffen und dem Vorhersehen des Pandemieverlaufs.Der InhaltBioinformatik ist einfach und schnell anzuwendenErste Detailanalysen (Sequenzen, Proteine, Gene)Analyse von Protein-NetzwerkenBioinformatik in der Infektionsbiologie und medizinische ImplikationenBioinformatik und Covid19 – ein globales PhänomenAnhang: Nützliche Webressourcen und LiteraturstellenDie ZielgruppenStudenten der Biologie und Medizin, die einen ersten Einblick in die Bioinformatik haben möchtenAllgemeines Publikum

Bioinformatik im Handlungsfeld der Forensik

by Dirk Labudde Marleen Mohaupt

Dieses Lehrbuch soll Studierenden den Einstieg in die Gebiete der Forensik und Bioinformatik gleichermaßen erleichtern. Anhand eines fiktiven Falls, der sich durch das gesamte Buch zieht, wird die Bioinformatik und deren Grundlagen in das Gebiet der Forensik übertragen. Der Fall deckt eine Vielzahl an biologischen Spuren, sowie deren klassische Analyse ab und definiert neue Handlungsfelder in der Bioinformatik und Forensik.In diesem Werk werden verschiedenste Bereiche der Forensik bioinformatisch aufbereitet: Genetischer Fingerabdruck: Auswertung auf Sequenz- statt auf Profilebene Fingerspuren: krankheitsbedingte bzw. genetisch bedingte VeränderungenUntersuchungen zum Phänotyp einer PersonGrundlegende Erkenntnisse zur Wundheilung sowie zur Blutalterung in- und ex-vivo Dieses Buch zeigt die Notwendigkeit auf, die Forensik um weitere Wissensbereiche zu ergänzen und gibt Einblicke in eine Vielzahl moderner Themen der Forensik wie zum Beispiel Populationsgenetik; Wundaltersbestimmung, Daktyloskopie oder Menschen ohne Fingerabdruck.Vor allem Studierende aus den Lebenswissenschaften sowie Dozierende ebendieser Fachrichtung, werden durch dieses Lehrbuch spannende Einblicke in topaktuelle Fragestellungen bekommen.

Bioinformatik: Ein einführendes Lehrbuch

by Thomas Dandekar Meik Kunz

Dieses Buch bietet eine packende Einf#65533;hrung in das am schnellsten wachsende Gebiet der Biologie mit leicht nachvollziehbaren Beispielen und einem gut aufbereitetem Anhang f#65533;r den Leser, der so gleich alles direkt nachkochen und miterleben kann. Das Buch holt den Leser bei den Grundlagen ab, wie man zum Beispiel Sequenzinformationen einfach erh#65533;lt und analysiert. In weiteren Kapiteln gehen die Autoren auf die verschiedenen Analysem#65533;glichkeiten von RNA, DNA und Proteinen bis hinzu ganzen Stoffwechselwegen ein. Dabei werden in jedem Kapitel spannende Beispiele aus der Biologie gew#65533;hlt, die zur Veranschaulichung der Analyse dienen. Jedes Kapitel wird mit einem #65533;bungsteil abgeschlossen, welches das Gelernte sogleich zur Anwendung bringt. Das Thema dieses Buches ist ein Muss f#65533;r jeden Biologiestudierenden, ob Bachelor- oder Masterstudium, da die Bioinformatik mittlerweile erstaunliche Einsichten in die molekularen Grundlagen aller Lebewesen zutage f#65533;rdert.

Bioinformatik: Ein einführendes Lehrbuch

by Thomas Dandekar Meik Kunz

Dieses Buch bietet eine packende Einführung in das am schnellsten wachsende Gebiet der Biologie mit leicht nachvollziehbaren Beispielen und einem gut aufbereiteten Anhang für die Leserschaft, um so gleich alles direkt nachkochen und miterleben zu können.Das Buch holt den Leser und die Leserin bei den Grundlagen ab, wie man zum Beispiel Sequenzinformationen einfach findet und dann analysiert. In weiteren Kapiteln gehen die Autoren auf die verschiedenen Analysemöglichkeiten von RNA, DNA und Proteinen bis hin zu ganzen Stoffwechselwegen ein. Dabei werden in jedem Kapitel spannende Beispiele aus der Biologie gewählt, die zur Veranschaulichung der Analyse dienen. Jedes Kapitel wird mit einem Übungsteil abgeschlossen, welches das Gelernte sogleich zur Anwendung bringt.Das Thema dieses Buches ist ein Muss für jeden Biologiestudierenden, ob Bachelor- oder Masterstudium, da die Bioinformatik mittlerweile erstaunliche Einsichten in die molekularen Grundlagen aller Lebewesen zutage fördert. Informatikstudierende und andere Studierende aus angrenzenden Naturwissenschaften bekommen einen guten Einstieg in die Bioinformatik, denn neben der Software werden systematisch die Biologie und aktuelle Themen (z.B. KI) Schritt für Schritt eingeführt.Entdecken Sie gemeinsam mit den Autoren den Schlüssel zum Leben und lernen Sie die Sprache des Lebens verstehen.

Bioinformatik: Grundlagen, Algorithmen, Anwendungen

by Rainer Merkl

Bioinformatik Der Marktführer bei den Bioinformatiklehrbüchern in neuer Auflage und mit dem neuen Thema Molekulardynamik Bioinformatik ist eine Kerndisziplin in den modernen Biowssenschaften, von der Biotechnologie über die Biochemie und Molekularbiologie bis zur Molekulargenetik und Molekularmedizin. Sie ist eine essenzielle Grundlage für alle “omics”-Technologien, für die Strukturbiologie, die Systembiologie sowie die synthetische Biologie. Bioinformatik. Grundlagen, Algorithmen, Anwendungen bietet eine umfassende Einführung in die wichtigsten Methoden der Bioinformatik. Der Autor erklärt dabei sowohl die mathematischen und biologischen Grundlagen als auch die wichtigsten Software-Tools und deren Anwendungsbereiche. Schwerpunkte sind Methoden zum Sequenzvergleich, Verfahren zur Charakterisierung von Proteinfamilien, Algorithmen zur Vorhersage von Protein- und RNA-Strukturen, Methoden des maschinellen Lernens und das Proteindesign. Für die 4. Auflage wurde der Text durchgehend aktualisiert und um ein Kapitel zur Molekulardynamik erweitert. Neu aufgenommene Exkurse zu Meilensteinen der Bioinformatik und aktuellen Anwendungsgebieten lockern den Text auf. Auf der ebenfalls komplett überarbeiteten Begleit-Webseite werden interaktive Lernmodule bereitgestellt, einschließlich mehr als 120 Übungsaufgaben, zum Teil mit Lösungen. Eine perfekte Einführung für alle Studenten der Lebenswissenschaften oder Informatik, die einen Einblick in die gängigen Methoden der Bioinformatik benötigen, sowie ein wertvoller Begleiter für alle, die bereits bioinformatische Werkzeuge nutzen und die zugrundeliegenden Konzepte verstehen möchten.

Bioinformatik: Sequenz - Struktur - Funktion

by Reinhard Rauhut

Die Bioinformatik ist für die Weiterentwicklung der modernen Biowissenschaften von herausragender Bedeutung. In Grundzügen wird sie Teil einer jeden Ausbildung zum Biologen oder Biochemiker werden. Obwohl die Zahl der angebotenen Lehrveranstaltungen rapide zunimmt, gibt es bisher auf dem deutschsprachigen Markt noch kein Lehrbuch zu dieser Thematik. Das vorliegende Werk schließt diese Lücke. Reich bebildert und mit relativ wenig mathematischem Formelaufwand werden die Grundlagen der Bioinformatik gut verständlich aufbereitet. Die Themenauswahl ist dabei auf die Bedürfnisse der experimentell tätigen Biochemiker, Biologen und Mediziner abgestimmt. Auf die wichtigsten Hilfsmittel, die das Internet kostenlos bietet, wird ausführlich eingegangen. Die Inhalte werden in der Abfolge Sequenz - Struktur - Funktion entwickelt: · Sequenzdatenbanken · Genomprojekte · Proteinorientierte Datenbanken · Techniken des eukaryontischen Genomassembly · Strukturdatenbanken · Expressionsanalyse mit DNA Chips · Proteomics · Phylogenie und Sequenz · DNA Computing Die Bioinformatik betrifft die tägliche Arbeit eines jeden Biowissenschaftlers. Es sollte sich daher jeder mit den grundlegenden Ansätzen vertraut machen.

Bioinformation Discovery: Data to Knowledge in Biology

by Pandjassarame Kangueane

This new edition continues to illustrate the power of biological data in knowledge discovery. It describes biological data types and representations with examples for creating a workflow in bioinformation discovery. The concepts in knowledge discovery from data are illustrated using line diagrams. The principles and concepts in knowledge discovery are used for the development of prediction models for simulations of biological reactions and events. Advanced topics in molecular evolution and cellular & molecular biology are addressed using bioinformation gleaned through discovery. Each chapter contains approximately 10 exercises for practice. This will help students to expand their problem solving skills in Bioinformation Discovery. In this new edition, there are three new chapters covering single nucleotide polymorphism, genes, proteins and disease, and protein functions driven by surface electrostatics.

Bioinformation Discovery: Data to Knowledge in Biology

by Pandjassarame Kangueane

Bioinformation Discovery illustrates the power of biological data in knowledge discovery. It describes biological data types and representations with examples for creating a workflow in Bioinformation discovery. The concepts in knowledge discovery from data are illustrated using line diagrams. The principles and concepts in knowledge discovery are used for the development of prediction models for simulations of biological reactions and events. Advanced topics in molecular evolution and cellular & molecular biology are addressed using Bioinformation gleaned through discovery. Each chapter contains approximately 10 exercises for practice. This will help students to expand their problem solving skills in Bioinformation Discovery. Each chapter concludes with a number of good problem sets to test mastery of the material.

Bioinformation Worlds and Futures (Routledge Studies in Anthropology)

by Ej Gonzalez-Polledo

This book sets out to define and consolidate the field of bioinformation studies in its transnational and global dimensions, drawing on debates in science and technology studies, anthropology and sociology. It provides situated analyses of bioinformation journeys across domains and spheres of interpretation. As unprecedented amounts of data relating to biological processes and lives are collected, aggregated, traded and exchanged, infrastructural systems and machine learners produce real consequences as they turn indeterminate data into actionable decisions for states, companies, scientific researchers and consumers. Bioinformation accrues multiple values as it transverses multiple registers and domains, and as it is transformed from bodies to becoming a subject of analysis tied to particular social relations, promises, desires and futures. The volume harnesses the anthropological sensibility for situated, fine-grained, ethnographically grounded analysis to develop an interdisciplinary dialogue on the conceptual, political, social and ethical dimensions posed by bioinformation.

Bioinformational Philosophy and Postdigital Knowledge Ecologies (Postdigital Science and Education)

by Sarah Hayes Michael A. Peters Petar Jandrić

The book presents a cross-disciplinary overview of critical issues at the intersections of biology, information, and society. Based on theories of bioinformationalism, viral modernity, the postdigital condition, and others, this book explores two inter-related questions: Which new knowledge ecologies are emerging? Which philosophies and research approaches do they require? The book argues that the 20th century focus on machinery needs to be replaced, at least partially, by a focus on a better understanding of living systems and their interactions with technology at all scales – from viruses, through to human beings, to the Earth’s ecosystem. This change of direction cannot be made by a simple relocation of focus and/or funding from one discipline to another. In our age of the Anthropocene, (human and planetary) biology cannot be thought of without (digital) technology and society. Today’s curious bioinformational mix of blurred and messy relationships between physics and biology, old and new media, humanism and posthumanism, knowledge capitalism and bio-informational capitalism defines the postdigital condition and creates new knowledge ecologies. The book presents scholarly research defining new knowledge ecologies built upon emerging forms of scientific communication, big data deluge, and opacity of algorithmic operations. Many of these developments can be approached using the concept of viral modernity, which applies to viral technologies, codes and ecosystems in information, publishing, education, and emerging knowledge (journal) systems. It is within these overlapping theories and contexts, that this book explores new bioinformational philosophies and postdigital knowledge ecologies.

Bioinked Boundaries: Patenting 3D Bioprinted Tissues, Organs and Bioinks: An US, European and Australian Patent Law Perspective

by Pratap Devarapalli

This book presents a comprehensive and comparative study of the patentability of bioprinting inventions, specifically bioinks and bioprinted tissues, in the US, the Europe and Australia. It employs a two-phase analysis to understand, ‘Is the patentable subject matter requirement a hurdle to patenting bioprinting inventions, specifically bioinks and bioprinted tissues?’ The first phase is a doctrinal analysis of the patent laws and jurisprudence in respective jurisdictions, highlighting the similarities and differences in their approaches to the subject matter requirement. The second phase is an empirical analysis of the patent prosecution data from patent applications filed in each jurisdiction with claims directed towards bioprinted tissues and bioinks, revealing how patent examiners apply the patent provisions to accept or object to such patent claims. The book offers several contributions to the field of bioprinting and patent law. First, it provides a detailed and up-to-date overview of the current state of the art and the legal landscape of bioprinting inventions. Second, it identifies the main criteria and factors that patent examiners use to assess the patentable subject matter of bioprinted tissues and bioinks, such as the level of human intervention, the markedly different characteristics, and the industrial applicability. Third, it proposes patenting framework models for each jurisdiction, which can assist patent applicants to draft and amend their patent claims in accordance with the patentable subject matter requirement. Fourth, it evaluates the potential benefits and implications of patenting bioprinting inventions for the bioprinting industry and society at large, such as fostering innovation, promoting public health, and indirectly addressing ethical and social issues. The main benefit that the reader will derive from the book is a deeper understanding of the patentability of bioprinting inventions, specifically bioinks and bioprinted tissues, in different jurisdictions and contexts. The book will help the reader to appreciate the legal and technical aspects of bioprinting and patent law, and how they affect the bioprinting industry and society at large.

Bioinoculants: Biological Option for Mitigating global Climate Change

by Surender Singh Radha Prasanna Kumar Pranaw

This edited book covers various bioinoculants for sustainable crop production under the changing global climate. The book envisages a compilation of articles relevant to the current status of production and use of novel microbial inoculants for different crops and highlights their role in mitigating global climate challenges. These include nutrient deficiencies, salinity, drought, and emerging pathogens. In addition, success stories and commercialization aspects are also discussed. Growing environmental concerns related to climate change can potentially decrease the global yield capacity of agricultural systems. Agricultural productivity is severely affected by major biotic and abiotic factors. The phytomicrobiome plays a critical role in the survival of the holobiont, particularly for plants growing in extreme environments. The use of microbial-based agricultural inputs has a long history, beginning with a broad-scale rhizobial inoculation of legumes in the early twentieth century. Microbial inoculants are considered one of the best and most effective strategies for sustainable agriculture under climate change, and a viable solution to meet the twin challenges of global food security and environmental sustainability. It is therefore imperative to understand the current status and development in the area of bioinoculants from a global perspective. The chapter’s focus would be on major agro-ecologies, covering all major crops across the globe, along with the commercialization status of different bioinoculants in different countries The book caters to the needs of the students, faculty, policymakers, and researchers working in the area of microbiology, biotechnology, environmental sciences, and botany.

Bioinorganic Catalysis

by Jan Reedijk Elisabeth Bouwman

"Provides the latest research results and suggests new topics for interdisciplinary study of metal ions, catalysis, and biochemical systems. Second Edition highlights potential applications; includes new chapters on zinc and FeS clusters; presents new X-ray analysis of metalloenzymes; and more."

Bioinorganic Chemistry -- Inorganic Elements in the Chemistry of Life

by Brigitte Schwederski Axel Klein Wolfgang Kaim

The field of Bioinorganic Chemistry has grown significantly in recent years; now one of the major sub-disciplines of Inorganic Chemistry, it has also pervaded other areas of the life sciences due to its highly interdisciplinary nature.Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life, Second Edition provides a detailed introduction to the role of inorganic elements in biology, taking a systematic element-by-element approach to the topic. The second edition of this classic text has been fully revised and updated to include new structure information, emerging developments in the field, and an increased focus on medical applications of inorganic compounds. New topics have been added including materials aspects of bioinorganic chemistry, elemental cycles, bioorganometallic chemistry, medical imaging and therapeutic advances.Topics covered include:Metals at the center of photosynthesisUptake, transport, and storage of essential elementsCatalysis through hemoproteinsBiological functions of molybdenum, tungsten, vanadium and chromiumFunction and transport of alkaline and alkaline earth metal cationsBiomineralizationBiological functions of the non-metallic inorganic elementsBioinorganic chemistry of toxic metalsBiochemical behavior of radionuclides and medical imaging using inorganic compoundsChemotherapy involving non-essential elements This full color text provides a concise and comprehensive review of bioinorganic chemistry for advanced students of chemistry, biochemistry, biology, medicine and environmental science.

Bioinorganic Chemistry: A Short Course

by Rosette M. Roat-Malone

Introduces students to the basics of bioinorganic chemistry This book provides the fundamentals for inorganic chemistry and biochemistry relevant to understanding bioinorganic topics. It provides essential background material, followed by detailed information on selected topics, to give readers the background, tools, and skills they need to research and study bioinorganic topics of interest to them. To reflect current practices and needs, instrumental methods and techniques are referred to and mixed in throughout the book. Bioinorganic Chemistry: A Short Course, Third Edition begins with a chapter on Inorganic Chemistry and Biochemistry Essentials. It then continues with chapters on: Computer Hardware, Software, and Computational Chemistry Methods; Important Metal Centers in Proteins; Myoglobins, Hemoglobins, Superoxide Dismutases, Nitrogenases, Hydrogenases, Carbonic Anhydrases, and Nitrogen Cycle Enzymes. The book concludes with chapters on Nanobioinorganic Chemistry and Metals in Medicine. Readers are also offered end-of-section summaries, conclusions, and thought problems. Reduces size of the text from previous edition to match the first, keeping it appropriate for a one-semester course Offers primers and background materials to help students feel comfortable with research-level bioinorganic chemistry Emphasizes select and diverse topics using extensive references from current scientific literature, with more emphasis on molecular biology in the biochemistry section, leading to a discussion of CRISPR technology Adds new chapters on hydrogenases, carbonic anhydrases, and nitrogen cycle enzymes, along with a separate chapter on nanobioinorganic chemistry Features expanded coverage of computer hardware and software, metalloenzymes, and metals in medicines Supplemented with a companion website for students and instructors featuring Powerpoint and JPEG figures and tables, arranged by chapter Appropriate for one-semester bioinorganic chemistry courses, Bioinorganic Chemistry: A Short Course, Third Edition is ideal for upper-level undergraduate and beginning graduate students. It is also a valuable reference for practitioners and researchers in need of a general introduction to the subject, as well as chemists requiring an accessible reference.

Bioinorganic Medicinal Chemistry

by Enzo Alessio

This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic.

Bioinsecurities: Disease Interventions, Empire, and the Government of Species

by Neel Ahuja

In Bioinsecurities Neel Ahuja argues that U.S. imperial expansion has been shaped by the attempts of health and military officials to control the interactions of humans, animals, viruses, and bacteria at the borders of U.S. influence, a phenomenon called the government of species. The book explores efforts to control the spread of Hansen's disease, venereal disease, polio, smallpox, and HIV through interventions linking the continental United States to Hawai'i, Panamá, Puerto Rico, Cuba, Congo, Iraq, and India in the twentieth and twenty-first centuries. Ahuja argues that racial fears of contagion helped to produce public optimism concerning state uses of pharmaceuticals, medical experimentation, military intervention, and incarceration to regulate the immune capacities of the body. In the process, the security state made the biological structures of human and animal populations into sites of struggle in the politics of empire, unleashing new patient activisms and forms of resistance to medical and military authority across the increasingly global sphere of U.S. influence.

Bioinspiration and Biomimicry in Chemistry

by Janine Benyus Jean-Marie Lehn Gerhard Swiegers

Can we emulate nature's technology in chemistry?Through billions of years of evolution, Nature has generated some remarkable systems and substances that have made life on earth what it is today. Increasingly, scientists are seeking to mimic Nature's systems and processes in the lab in order to harness the power of Nature for the benefit of society.Bioinspiration and Biomimicry in Chemistry explores the chemistry of Nature and how we can replicate what Nature does in abiological settings. Specifically, the book focuses on wholly artificial, man-made systems that employ or are inspired by principles of Nature, but which do not use materials of biological origin.Beginning with a general overview of the concept of bioinspiration and biomimicry in chemistry, the book tackles such topics as:Bioinspired molecular machinesBioinspired catalysisBiomimetic amphiphiles and vesiclesBiomimetic principles in macromolecular scienceBiomimetic cavities and bioinspired receptorsBiomimicry in organic synthesisWritten by a team of leading international experts, the contributed chapters collectively lay the groundwork for a new generation of environmentally friendly and sustainable materials, pharmaceuticals, and technologies. Readers will discover the latest advances in our ability to replicate natural systems and materials as well as the many impediments that remain, proving how much we still need to learn about how Nature works.Bioinspiration and Biomimicry in Chemistry is recommended for students and researchers in all realms of chemistry. Addressing how scientists are working to reverse engineer Nature in all areas of chemical research, the book is designed to stimulate new discussion and research in this exciting and promising field.

Bioinspiration: From Nano to Micro Scales (Biological and Medical Physics, Biomedical Engineering)

by Xiang Yang Liu

Methods in bioinspiration and biomimicking have been around for a long time. However, due to current advances in modern physical, biological sciences, and technologies, our understanding of the methods have evolved to a new level. This is due not only to the identification of mysterious and fascinating phenomena but also to the understandings of the correlation between the structural factors and the performance based on the latest theoretical, modeling, and experimental technologies. Bioinspiration: From Nano to Micro Scale provides readers with a broad view of the frontiers of research in the area of bioinspiration from the nano to macroscopic scales, particularly in the areas of biomineralization, antifreeze protein, and antifreeze effect. It also covers such methods as the lotus effect and superhydrophobicity, structural colors in animal kingdom and beyond, as well as behavior in ion channels. A number of international experts in related fields have contributed to this book, which offers a comprehensive and synergistic look into challenging issues such as theoretical modeling, advanced surface probing, and fabrication. The book also provides a link to the engineering of novel advanced materials playing an important role in advancing technologies in various fields.

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