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Biomimicked Biomaterials: Advances in Tissue Engineering and Regenerative Medicine (Advances in Experimental Medicine and Biology #1250)
by Rui L. Reis Heung Jae Chun Gilson Khang Antonella MottaThis book is the second of two volumes that together offer a comprehensive account of cutting-edge advances in the development of biomaterials for use within tissue engineering and regenerative medicine. In this volume, which is devoted to biomimetic biomaterials, the opening section discusses bone regeneration by means of duck’s feet-derived collagen scaffold and the use of decellularized extracellular matrices. The role of various novel biomimetic hydrogels in regenerative medicine is then considered in detail. The third section focuses on the control of stem cell fate by biomimetic biomaterials, covering exosome-integrated biomaterials for bone regeneration, cellular responses to materials for biomedical engineering, and the regulation of stem cell functions by micropatterned structures. Finally, the use of nano-intelligent biocomposites in regenerative medicine is addressed, with discussion of, for example, recent advances in biphasic calcium phosphate bioceramics and blood-contacting polymeric biomaterials. The authors are recognized experts in the interdisciplinary field of regenerative medicine and the book will be of value for all with an interest in regenerative medicine based on biomaterials.
Biomimicry
by Janine M. BenyusThis profound and accessible book details how science is studying nature's best ideas to solve our toughest 21st-century problems. If chaos theory transformed our view of the universe, biomimicry is transforming our life on Earth. Biomimicry is innovation inspired by nature - taking advantage of evolution's 3.8 billion years of R&D since the first bacteria. Biomimics study nature's best ideas: photosynthesis, brain power, and shells - and adapt them for human use. They are revolutionising how we invent, compute, heal ourselves, harness energy, repair the environment, and feed the world. Science writer and lecturer Janine Benyus names and explains this phenomenon. She takes us into the lab and out in the field with cutting-edge researchers as they stir vats of proteins to unleash their computing power; analyse how electrons zipping around a leaf cell convert sunlight into fuel in trillionths of a second; discover miracle drugs by watching what chimps eat when they're sick; study the hardy prairie as a model for low-maintenance agriculture; and more.
Biomimicry Materials and Applications
by Inamuddin Tariq Altalhi Ashjan AlrogiBIOMIMICRY MATERIALS AND APPLICATIONS Since the concept of biomimetics was first developed in 1950, the practical applications of biomimetic materials have created a revolution from biotechnology to medicine and most industrial domains, and are the future of commercial work in nearly all fields. Biomimetic materials are basically synthetic materials or man-made materials which can mimic or copy the properties of natural materials. Scientists have created a revolution by mimicking natural polymers through semi-synthetic or fully synthetic methods. There are different methods to mimic a material, such as copying form and shape, copying the process, and finally mimicking at an ecosystem level. This book comprises a detailed description of the materials used to synthesize and form biomimetic materials. It describes the materials in a way that will be far more convenient and easier to understand. The editors have compiled the book so that it can be used in all areas of research, and it shows the properties, preparations, and applications of biomimetic materials currently being used. Readers of this volume will find that: It introduces the synthesis and formation of biomimetic materials; Provides a thorough overview of many industrial applications, such as textiles, management of plant disease detection, and various applications of electroactive polymers; Presents ideas on sustainability and how biomimicry fits within that arena; Deliberates the importance of biomimicry in novel materials. Audience This is a useful guide for engineers, researchers, and students who work on the synthesis, properties, and applications of existing biomimetic materials in academia and industrial settings.
Biomimicry and Business: How Companies Are Using Nature's Strategies to Succeed
by Margo FarnsworthBiomimicry, the practice of observing then mimicking nature’s strategies to solve business challenges, offers a path to healthy profit while working in partnership, and even reciprocity, with the natural world. Other books have described biomimicry, its uses, and its benefits. This book shows readers how to create their own biomimetic or bioinspired solutions with clear benefits to the bottom line, the environment, and people. Fashioned through storytelling, this book blends snapshots of five successful companies – Nike, Interface, Inc., PAX Scientific, Sharklet Technologies, and Encycle – which decided to partner with nature by deploying biomimicry. The book details how they discovered the practices, introduced them to staff, engaged in the process, and measured outcomes. The book concludes with challenges for readers to determine their own next steps in business and offers practical and useful resources to get there. By revealing the stories of each professional’s journey with lessons they learned, then providing resources and issuing a challenge and pathway to do business better, this book serves as a tool for entrepreneurs, seasoned professionals, and students to emulate nature’s brilliance, apply it at work, and contribute to a healthier, more prosperous world.
Biomimicry and Sustainable Building Performance: A Nature-inspired Sustainability Guide for the Built Environment (Routledge Research Collections for Construction in Developing Countries)
by Clinton Ohis Aigbavboa Olusegun Aanuoluwapo OguntonaThis book on biomimicry assessment tools studies the concepts of sustainability, sustainable construction practices, and the evaluation categories that constitute a sustainability assessment tool. By exploring and drawing lessons from biomimicry principles, the book provides a nature-inspired assessment tool to aid and guide the sustainable transformation of the built environment. The book encapsulates the attributes of the conceptualised biomimicry assessment tool, which is aimed at helping practitioners, regulatory bodies, and governmental and non-governmental agencies in greening the built environment. Owing to the dire need for country-specific and tailor-made tools that address developing countries' needs, this book serves as a practical reference and theoretical springboard for the development of sustainability assessment tools for the built environment. Furthermore, the book serves as a guide in navigating the path towards achieving the greening agendas of the built environment and other sectors and seeks to align the new biomimicry assessment tool with the UN Sustainable Development Goals (SDGs). It is important reading for academics, professionals and advanced students in the built environment, engineering, and sustainable development.
Biomimicry in Architecture
by Michael PawlynWhen searching for genuinely sustainable building design and technology - designs that go beyond conventional sustainability to be truly restorative - we often find that nature got there first. Over 3.5 billion years of natural history have evolved innumerable examples of forms, systems, and processes that can be applied to modern green design. For architects, urban designers and product designers, this new edition of Biomimicry in Architecture looks to the natural world to achieve radical increases in resource efficiency. Packed with case studies predicting future trends, this edition also contains updated and expanded chapters on structures, materials, waste, water, thermal control and energy, as well as an all-new chapter on light. An amazing sourcebook of extraordinary design solutions, Biomimicry in Architecture is a must-read for anyone preparing for the challenges of building a sustainable and restorative future.
Biomimicry: When Nature Inspires Amazing Inventions
by Seraphine MenuNature did it first! A beautiful and whimsically illustrated explanation of cool inventions like Velcro and scuba suits that were inspired by the natural worldDiscover how bats led to the development of radar, whales inspired the pacemaker, and the lotus flower may help us produce indestructible clothing. "Biomimicry" comes from the Greek "bio" (life) and "mimesis" (imitation)." Here are various and amazing ways that nature inspires us to create cool inventions in science and medicine, clothing design, and architecture. From the fireflies that showed inventors how LEDs could give off more light to the burdock plant that inspired velcro to the high speed trains of Japan that take the form of a kingfisher's sleek, aerodynamic head, there are innumerable ways that we can create smarter, better, safer inventions by observing the natural world. Author Seraphine Menu and illustrator Emmanuelle Walker also gently explain that our extraordinary, diverse, and awe-inspiring world is like a carefully calibrated machine and its fragile balance must be treated with extreme care and respect. "Go outside," they say, "observe, compare, and maybe some day you'll be the next person to be struck by a great idea."
Biomineralization Mechanism of the Pearl Oyster, Pinctada fucata
by Zhenguang Yan Rongqing Zhang Liping XieThis book presents an overview of our current understanding of the biomineralization mechanisms for shell formation in the pearl oyster Pinctada fucata, based on molecular biology, biochemistry, cell biology, structural biology and environmental biology. Pinctada fucata is the major pearl-producing shellfish in the South China Sea and is also an established model system for the research on the nacre biomineralization mechanism. Extensive studies on nacre biomineralization have provided valuable information for novel bionic material design. Discussing the isolation and gene cloning of the matrix proteins involved in the shell formation, as well as the cell signaling pathways, shell microstructures, and the environmental impacts on shell biomineralization, it is a valuable reference resource for researchers working in the field of nacre biomineralization and biomaterials.
Biomineralization Sourcebook: Characterization of Biominerals and Biomimetic Materials
by Laurie B. Gower Elaine DiMasiWhat does it mean to be at the forefront of a characterization technique? Novel implementation and research, finding new ways to visualize composites, and new techniques all play a role. Yet with the myriad of advances in the field, keeping up with new and advanced techniques, often from many different areas, has become a challenge. Biomineralizati
Biomineralization: From Molecular and Nano-structural Analyses to Environmental Science
by Kazuyoshi Endo Toshihiro Kogure Hiromichi NagasawaThis open access book is the proceedings of the 14th International Symposium on Biomineralization (BIOMIN XIV) held in 2017 at Tsukuba. Over the past 45 years, biomineralization research has unveiled details of the characteristics of the nano-structure of various biominerals; the formation mechanism of this nano-structure, including the initial stage of crystallization; and the function of organic matrices in biominerals, and this knowledge has been applied to dental, medical, pharmaceutical, materials, agricultural and environmental sciences and paleontology. As such, biomineralization is an important interdisciplinary research area, and further advances are expected in both fundamental and applied research.
Biomining Technologies: Extracting and Recovering Metals from Ores and Wastes
by Michael Schlömann David Barrie Johnson Christopher George Bryan Francisco Figueroa RobertoThis book describes emerging and established industrial processes of biomining technologies used for the recovery of metals of economic interest from, e.g. mineral ores, mining and electronic wastes using microbiological technologies. Multiple chapters focus on engineering design and operation of biomining systems. Several industrial case studies from China, Chile, Peru, Russia/Kazakhstan and Finland are included, which emphasises the practical approach of the book. The reader not only learns more about the biology, diversity and ecology of microorganisms involved in biomining processes, but also about microbial biomolecular and cultivation tools used in the biomining industry. Special emphasis is put on emerging biotechnologies enabling the use of biomining for recycling metals from e-wastes, waste streams and process waters. Finally, the future impacts and direction of biomining towards sustainability in a metal-demanding world are also highlighted.The book is aimed at an interdisciplinary audience involving operators and researchers working across disciplines including geology, chemical engineering, microbiology and molecular biology. This is reflected by the content of this book, as well as by its authors, who are all leading practitioners and authorities in their fields.
Biomolecular Action of Ionizing Radiation (Series in Medical Physics and Biomedical Engineering)
by Shirley LehnertEmbracing the transformation of radiation sciences by the recent surge of developments in molecular biology, this progressive text offers an up-to-date analysis of in vitro and in vivo molecular responses in the body induced by ionizing radiation. With a unique emphasis on medical physics applications, Biomolecular Action of Ionizi
Biomolecular Archaeology: An Introduction
by Keri Brown T. A. BrownIllustrated thoroughly, Biomolecular Archaeology is the first book to clearly guide students through the study of ancient DNA: how to analyze biomolecular evidence (DNA, proteins, lipids and carbohydrates) to address important archaeological questions. The first book to address the scope and methods of this new cross-disciplinary area of research for archaeologists Offers a completely up-to-date overview of the latest research in this innovative subject Guides students who wish to become biomolecular archaeologists through the complexities of both the scientific methods and archaeological goals. Provides an essential component to undergraduate and graduate archaeological research
Biomolecular Crystallography: Principles, Practice, and Application to Structural Biology
by Bernhard RuppSynthesizing over thirty years of advances into a comprehensive textbook, Biomolecular Crystallography describes the fundamentals, practices, and applications of protein crystallography. Illustrated in full-color by the author, the text describes mathematical and physical concepts in accessible and accurate language. Biomolecular Crystallography will be a valuable resource for advanced undergraduate and graduate students and practitioners in structural biology, crystallography, and structural bioinformatics.
Biomolecular EPR Spectroscopy
by Wilfred Raymond HagenComprehensive, Up-to-Date Coverage of Spectroscopy Theory and its Applications to Biological SystemsAlthough a multitude of books have been published about spectroscopy, most of them only occasionally refer to biological systems and the specific problems of biomolecular EPR (bioEPR). Biomolecular EPR Spectroscopy provides a practical introduction t
Biomolecular Engineering Solutions for Renewable Specialty Chemicals: Microorganisms, Products, and Processes
by Rajesh K. Sani R. Navanietha KrishnarajDiscover biomolecular engineering technologies for the production of biofuels, pharmaceuticals, organic and amino acids, vitamins, biopolymers, surfactants, detergents, and enzymes In Biomolecular Engineering Solutions for Renewable Specialty Chemicals, distinguished researchers and editors Drs. R. Navanietha Krishnaraj and Rajesh K. Sani deliver a collection of insightful resources on advanced technologies in the synthesis and purification of value-added compounds. Readers will discover new technologies that assist in the commercialization of the production of value-added products. The editors also include resources that offer strategies for overcoming current limitations in biochemical synthesis, including purification. The articles within cover topics like the rewiring of anaerobic microbial processes for methane and hythane production, the extremophilic bioprocessing of wastes to biofuels, reverse methanogenesis of methane to biopolymers and value-added products, and more. The book presents advanced concepts and biomolecular engineering technologies for the production of high-value, low-volume products, like therapeutic molecules, and describes methods for improving microbes and enzymes using protein engineering, metabolic engineering, and systems biology approaches for converting wastes. Readers will also discover: A thorough introduction to engineered microorganisms for the production of biocommodities and microbial production of vanillin from ferulic acid Explorations of antibiotic trends in microbial therapy, including current approaches and future prospects, as well as fermentation strategies in the food and beverage industry Practical discussions of bioactive oligosaccharides, including their production, characterization, and applications In-depth treatments of biopolymers, including a retrospective analysis in the facets of biomedical engineering Perfect for researchers and practicing professionals in the areas of environmental and industrial biotechnology, biomedicine, and the biological sciences, Biomolecular Engineering Solutions for Renewable Specialty Chemicals is also an invaluable resource for students taking courses involving biorefineries, biovalorization, industrial biotechnology, and environmental biotechnology.
Biomolecular Feedback Systems
by Richard Murray Domitilla Del VecchioThis book provides an accessible introduction to the principles and tools for modeling, analyzing, and synthesizing biomolecular systems. It begins with modeling tools such as reaction-rate equations, reduced-order models, stochastic models, and specific models of important core processes. It then describes in detail the control and dynamical systems tools used to analyze these models. These include tools for analyzing stability of equilibria, limit cycles, robustness, and parameter uncertainty. Modeling and analysis techniques are then applied to design examples from both natural systems and synthetic biomolecular circuits. In addition, this comprehensive book addresses the problem of modular composition of synthetic circuits, the tools for analyzing the extent of modularity, and the design techniques for ensuring modular behavior. It also looks at design trade-offs, focusing on perturbations due to noise and competition for shared cellular resources.Featuring numerous exercises and illustrations throughout, Biomolecular Feedback Systems is the ideal textbook for advanced undergraduates and graduate students. For researchers, it can also serve as a self-contained reference on the feedback control techniques that can be applied to biomolecular systems.Provides a user-friendly introduction to essential concepts, tools, and applicationsCovers the most commonly used modeling methodsAddresses the modular design problem for biomolecular systemsUses design examples from both natural systems and synthetic circuitsSolutions manual (available only to professors at press.princeton.edu)An online illustration package is available to professors at press.princeton.edu
Biomolecular Films: Design, Function, and Applications (Surfactant Science Ser. #111)
by James F. RuslingThis text examines films of biomolecules that can provide solid surfaces for catalyzing enzyme reactions, serve in biosensors and as biorecognition elements, mediate nanoparticle formation, and provide a basis for fundamental studies and applications in biomedicine and biomedical devices.
Biomolecular Imaging at High Spatial and Temporal Resolution In Vitro and In Vivo (Springer Theses)
by Thomas Harry SharpAs part of a collaboration between two different groups in chemistry and biochemistry, Thom Sharp presents here his thesis work on the development of new methods for cryoelectron microscopy. Throughout his Ph. D. , Thom had to master a whole range of techniques including modelling, molecular biology and microscopy. Using these skills to tackle an outstanding problem, the pursuit of high-resolution structures of peptide-based materials, Thom highlights in this thesis his newly developed methods for analysing and processing this particular type of electron microscopy data. This thesis gives the first molecular description of a de-novo designed peptide-based material. In general, this research will have a huge impact on the peptide assembly field, and also in electron microscopy as it introduces new methods and approaches, all of which are Thom's inventions and are described in this thesis.
Biomolecular Information Processing
by Evgeny KatzEdited by a renowned and much cited chemist, this book covers the whole span of molecular computers that are based on biomolecules. The contributions by all the major scientists in the field provide an excellent overview of the latest developments in this rapidly expanding area. A must-have for all researchers working on this very hot topic. Perfectly complements Molecular and Supramolecular Information Processing, also by Prof. Katz, and available as a two-volume set.
Biomolecular Interfaces: Interactions, Functions and Drug Design
by Ariel Fernández StiglianoThe book focuses on the aqueous interface of biomolecules, a vital yet overlooked area of biophysical research. Most biological phenomena cannot be fully understood at the molecular level without considering interfacial behavior. The author presents conceptual advances in molecular biophysics that herald the advent of a new discipline, epistructural biology, centered on the interactions of water and bio molecular structures across the interface. The author introduces powerful theoretical and computational resources in order to address fundamental topics such as protein folding, the physico-chemical basis of enzyme catalysis and protein associations. On the basis of this information, a multi-disciplinary approach is used to engineer therapeutic drugs and to allow substantive advances in targeted molecular medicine. This book will be of interest to scientists, students and practitioners in the fields of chemistry, biophysics and biomedical engineering.
Biomolecular Kinetics: A Step-by-Step Guide (Foundations of Biochemistry and Biophysics)
by Clive R. Bagshaw"a gem of a textbook which manages to produce a genuinely fresh, concise yet comprehensive guide"–Mark Leake, University of York "destined to become a standard reference…. Not just a ‘how to’ handbook but also an accessible primer in the essentials of kinetic theory and practice."–Michael Geeves, University of Kent "covers the entire spectrum of approaches, from the traditional steady state methods to a thorough account of transient kinetics and rapid reaction techniques, and then on to the new single molecule techniques" –Stephen Halford, University of Bristol This illustrated treatment explains the methods used for measuring how much a reaction gets speeded up, as well as the framework for solving problems such as ligand binding and macromolecular folding, using the step-by-step approach of numerical integration. It is a thoroughly modern text, reflecting the recent ability to observe reactions at the single-molecule level, as well as advances in microfluidics which have given rise to femtoscale studies. Kinetics is more important now than ever, and this book is a vibrant and approachable entry for anyone who wants to understand mechanism using transient or single molecule kinetics without getting bogged down in advanced mathematics. Clive R. Bagshaw is Emeritus Professor at the University of Leicester, U.K., and Research Associate at the University of California at Santa Cruz, U.S.A.
Biomolecular Sensors
by Christopher R. Lowe Electra GizeliThe development of devices that incorporate biological assemblies is impacting analytical and biomedical research. Today, scientists can monitor vital biological interactions-such as the binding of DNA to proteins-in real time, deriving unique information necessary to understanding biochemical pathways and thus aiding the design of drugs to regulat
Biomolecular Simulations in Structure-Based Drug Discovery (Methods and Principles in Medicinal Chemistry)
by Raimund Mannhold Jörg Holenz Helmut Buschmann Francesco L. Gervasio Vojtech SpiwokA timely and topical survey of modern simulation tools and their applications in real-life drug discovery, allowing for better and quicker results in structure-based drug design. The first part of this practical guide for industry professionals describes common tools used in the biomolecular simulation of drugs and their targets. A critical analysis of the accuracy of the predictions, the integration of modeling with other experimental data combined with numerous case studies from different therapeutic fields enable users to quickly adopt these new methods for their current projects. The second part then shows how these tools can be applied to drug discovery and development projects. Modeling experts from the pharmaceutical industry and from leading academic institutions present real-life examples for important target classes such as GPCRs, kinases and amyloids as well as for common challenges in structure-based drug discovery. With its inclusion of novel methods and strategies for the modeling of drug-target interactions in the framework of real-life drug discovery and development, this application-oriented reference is tailor-made for medicinal chemists and those working in the pharmaceutical industry.