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Biopharmaceutical Supply Chains: Distribution, Regulatory, Systems and Structural Changes Ahead
by Robert HandfieldA comprehensive exploration of the massive changes in the biopharmaceutical supply chain that have occurred during the past 10 years, and predicted future trends, Biopharmaceutical Supply Chains: Distribution, Regulatory, Systems and Structural Changes Ahead documents the specific impacts of these changes for key players in the supply chain. Based
Biopharmaceuticals
by Gary WalshThe latest edition of this highly acclaimed textbook, provides a comprehensive and up-to-date overview of the science and medical applications of biopharmaceutical products. Biopharmaceuticals refers to pharmaceutical substances derived from biological sources, and increasingly, it is synonymous with 'newer' pharmaceutical substances derived from genetic engineering or hybridoma technology.This superbly written review of the important areas of investigation in the field, covers drug production, plus the biochemical and molecular mechanisms of action together with the biotechnology of major biopharmaceutical types on the market or currently under development. There is also additional material reflecting both the technical advances in the area and detailed information on key topics such as the influence of genomics on drug discovery.
Biopharmaceuticals in Plants: Toward the Next Century of Medicine
by Kathleen Laura HefferonTransgenic plants present enormous potential to become one of the most cost-effective and safe systems for large-scale production of proteins for industrial, pharmaceutical, veterinary, and agricultural uses. Over the past decade, much progress has been made with respect to the development of vaccines, antibodies, and other therapeutic proteins. Bi
Biopharmaceuticals: Challenges and Opportunities
by Basanta Kumara BeheraBiopharmaceuticals: Challenges and Opportunities This book highlights how the traditional microbial process technology has been upgraded for the production of biologic drugs how manufacturing processes have evolved to meet the global market demand with quality products under the guidelines of internally recognized regulatory bodies. It also carries information on how, armed with a deeper understanding of life-threatening diseases, biopharmaceutical companies and the life sciences industry have developed formal and informal partnerships with researchers in institutes, universities, and other R&D organizations to fulfil timely, quality production with perfect safety and security. One of the most interesting aspects of this book is the conceptual development of personalized medicine (or precision medicine) to provide the right treatment to the right patient, at the right dose at an earlier stage of development, for genetic diseases. Besides this, it also highlights the most challenging aspects of modern biopharmaceutical science, focusing on the hot topics such as design and development of biologic drugs; the use of diversified groups of host cells belonging to animals, plants, microbes, insects, and mammals; stem cell therapy and gene therapy; supply chain management of biopharmaceuticals; and the future scope of biopharmaceutical industry development. This book is the latest resource for a wide circle of scientists, students, and researchers involved in understanding and implementing the knowledge of biopharmaceuticals to develop life-saving biologic drugs and to bring awareness to the development of personalized treatment that can potentially offer patients a faster diagnosis, fewer side effects, and better outcomes. Features: Explains how the traditional cell culture methodology has been changed to a fully continuous or partially continuous process Explains how to design and fabricate living organs of body by 3D bioprinting technology Focuses on how a biopharmaceutical company deals with various problems of regulatory bodies and develops innovative biologic drugs Narrates in detail the updated information on stem cell therapy and gene therapy Explains the development strategies and clinical significance of biosimilars and biobetters Highlights the supply chain management of biopharmaceuticals
Biopharmaceutics Modeling and Simulations
by Kiyohiko SuganoA comprehensive introduction to using modeling and simulation programs in drug discovery and developmentBiopharmaceutical modeling has become integral to the design and development of new drugs. Influencing key aspects of the development process, including drug substance design, formulation design, and toxicological exposure assessment, biopharmaceutical modeling is now seen as the linchpin to a drug's future success. And while there are a number of commercially available software programs for drug modeling, there has not been a single resource guiding pharmaceutical professionals to the actual tools and practices needed to design and test safe drugs.A guide to the basics of modeling and simulation programs, Biopharmaceutics Modeling and Simulations offers pharmaceutical scientists the keys to understanding how they work and are applied in creating drugs with desired medicinal properties. Beginning with a focus on the oral absorption of drugs, the book discusses:The central dogma of oral drug absorption (the interplay of dissolution, solubility, and permeability of a drug), which forms the basis of the biopharmaceutical classification system (BCS)The concept of drug concentrationHow to simulate key drug absorption processesThe physiological and drug property data used for biopharmaceutical modelingReliable practices for reporting resultsWith over 200 figures and illustrations and a peerless examination of all the key aspects of drug research--including running and interpreting models, validation, and compound and formulation selection--this reference seamlessly brings together the proven practical approaches essential to developing the safe and effective medicines of tomorrow.
Biopharmaceutics and Clinical Pharmacokinetics: An Introduction, Fourth Edition
by Robert E. NotariFor a decade and a half, Biopharmaceutics and Clinical Pharmacokinetics has been used in theclassrooms around the world as an introductory textbook on biophannaceutics and phannacokinetics. Now, the new Fourth Edition, Revised and Expanded further enhances the preceding editions'proven features, introducing significant advances in clinical pharmacokinetics, pharmacokineticdesign of drugs and dosage forms, and model-independent analyses. Still usable without prior knowledge of calculus or kinetics, this successfully implemented workbookmaintains a carefully graduated "building block" presentation, incorporating sample problemsand exercises throughout for a thorough understanding of the material.Biopharmaceutics and Clinical Pharmacokinetics features a growth-oriented format that systematicallydevelops and interrelates all subject matter .. . introduces basic theory and fields of application... emphasizes model-independent pharmacokinetic analyses ... presents biopharmaceutical aspectsof product design and evaluation .. . offers a unique approach to teaching dosage regimen design andindividualization . .. and considers structural modification of drug molecules for problems associatedwith pharmacokinetics. As a comprehensive coverage of the basic principles and the recent achievements in the field, noother textbook does as much for students of pharmacy, pharmacology, medicinal chemistry, andmedicine, or for scientists who desire a simple but thorough introduction to theory and application.
Biopharmaceutics of Ocular Drug Delivery (Routledge Revivals)
by Peter EdmanA significant new book on drug delivery to the eyeBiopharmaceutics of Ocular Drug Delivery examines the current physiological, anatomical, pharmaceutical/technological, and biopharmaceutical knowledge on ocular drug delivery. Leading ophthalmic researchers cover topics such as the formulation and usage of ophthalmic solutions and suspensions, the influence of surfactants and preservatives on ocular drug absorption, and new techniques that include bioadhesion and the use of hyaluronic acid as an ophthalmic vehicle. Promising research on new delivery systems for improved drug therapy is highlighted, including new pharmaceutical vehicles, inserts, liposomes, nanoparticles, and prodrugs. Biopharmaceutics of Ocular Drug Delivery is one of the few books available on drug delivery to the eye and will be an important reference for ophthalmologists, pharmacologists, pharmaceutical researchers, and other scientists interested in the topic.
Biopharmaceutics: From Fundamentals to Industrial Practice (Advances in Pharmaceutical Technology)
by Hannah BatchelorExplore the latest research in biopharmaceutics from leading contributors in the field In Biopharmaceutics - From Fundamentals to Industrial Practice, distinguished Scientists from the UK's Academy of Pharmaceutical Sciences Biopharmaceutica Focus Group deliver a comprehensive examination of the tools used within the field of biopharmaceutics and their applications to drug development. This edited volume is an indispensable tool for anyone seeking to better understand the field of biopharmaceutics as it rapidly develops and evolves. Beginning with an expansive introduction to the basics of biopharmaceutics and the context that underpins the field, the included resources go on to discuss how biopharmaceutics are integrated into product development within the pharmaceutical industry. Explorations of how the regulatory aspects of biopharmaceutics function, as well as the impact of physiology and anatomy on the rate and extent of drug absorption, follow. Readers will find insightful discussions of physiologically based modeling as a valuable asset in the biopharmaceutics toolkit and how to apply the principles of the field to special populations. The book goes on to discuss: Thorough introductions to biopharmaceutics, basic pharmacokinetics, and biopharmaceutics measures Comprehensive explorations of solubility, permeability, and dissolution Practical discussions of the use of biopharmaceutics to inform candidate drug selection and optimization, as well as biopharmaceutics tools for rational formulation design In-depth examinations of biopharmaceutics classification systems and regulatory biopharmaceutics, as well as regulatory biopharmaceutics and the impact of anatomy and physiology Perfect for professionals working in the pharmaceutical and biopharmaceutical industries, Biopharmaceutics - From Fundamentals to Industrial Practice is an incisive and up-to-date resource on the practical, pharmaceutical applications of the field.
Biopharmazie
by Peter Langguth Heidi Wunderli-Allenspach Gert FrickerDurch die j ngste nderung der Approbationsordnung f r Apotheker hat die Bedeutung der Biopharmazie in Forschung und Lehre weiter zugenommen. In diesem vollst ndig neu konzipierten Lehr- und Handbuch behandeln renommierte Autoren s mtliche Themen der Biopharmazie entsprechend den neuen Anforderungen. Aktuell und bersichtlich, richtet sich das Grundlagenwerk an Pharmazeuten in Wissenschaft und Industrie, aber auch an Studenten, die besonders von den integrierten bungsteilen profitieren. Die Hauptkapitel zu den Grundlagen der Physiologie und Pharmakokinetik werden erg nzt durch Abschnitte zu Anwendungen der Biopharmazie in der Arzneimittelentwicklung und in der Klinik. Zu topaktuellen Themen wie Prodrugs und Drug Targeting referiert der Band den Stand der Forschung. F r Praktiker h lt er au erdem ein Kapitel zu Computerprogrammen in der Biopharmazie bereit. Auch Studenten hat das Buch eine Menge zu bieten: Zahlreiche bungsaufgaben sowie Verst ndnisfragen mit den dazugeh rigen Antworten erlauben eine effektive Lernkontrolle und damit eine optimale Pr fungsvorbereitung. Der Band folgt der Terminologie der Europ ischen Pharmakop e 2001. Das ausf hrliche Glossar enth lt mehr als 100 Begriffe. Au erdem werden ber 130 pharmakokinetische Abk rzungen und Symbole erkl rt, so dass das Buch auch als Nachschlagewerk genutzt werden kann. Das Autorenteam hat sich einiges vorgenommen: Ihr Buch soll das Referenzwerk der Biopharmazie werden, f r Studenten und Dozenten der Pharmazie, Pharmazeuten und Pharmakologen ebenso wie f r Praktiker in der Pharmaindustrie.
Biophilia
by Edward O. WilsonBiophilia is Edward O. Wilson's most personal book, an evocation of his own response to nature and an eloquent statement of the conservation ethic. Wilson argues that our natural affinity for life—biophilia—is the very essence of our humanity and binds us to all other living species.
Biophilia: You + Nature + Home
by Sally CoulthardIn this beautifully illustrated guide, best-selling author Sally Coulthard demonstrates how to transform your living and working spaces into places that put you in touch with nature.Eight inspiring chapters cover key elements for the 'biophilic home', including materials, views, colour and natural light. Each section explores the links between home, health and happiness, drawing on environmental research and neuroscience while making practical suggestions for bringing the natural world into your home.Bring nature indoors with flowers and plants, rediscover the innate pleasure of real fires and fresh air, and learn how to improve your mood and sleep patterns with dynamic light. Create a space filled with natural elements, patterns, nature's colours, fabrics and textures that lift your mood; find out why natural sounds and water are soothing; and learn how to make small changes that will inspire, invigorate and enrich your relationship with the natural world.'As best-selling author and designer, Sally Coulthard, reveals in this guide, creating a 'biophilic home' can have a huge impact on your wellbeing; improving your mood and encouraging healthier sleep patterns...Be it plants, materials, colour or light, it's enlightening to see how small changes can make a big difference, while deepening your respect and correlation to the natural world.' FORBES Magazine'How to embrace the natural world by transforming your interior spaces with specific materials, colours, views and sounds.' Gardens Illustrated'Humans are mammals, programmed over millennia to respond to the natural world. We may be able to live and work in man-made environments most of the time. But according to a new movement of "biophilic" designers and enthusiasts, we are not thriving...writer Sally Coulthard likens it to the practice of keeping animals in captivity, in surroundings ill-suited to their needs. "We live in a world that is fundamentally mismatched to our evolutionary adaptation - we don't see, hear and feel the things that we are programmed to respond to," she writes.' Financial Times
Biophilia: You + Nature + Home
by Sally CoulthardIn this beautifully illustrated guide, best-selling author Sally Coulthard demonstrates how to transform your living and working spaces into places that put you in touch with nature.Eight inspiring chapters cover key elements for the 'biophilic home', including materials, views, colour and natural light. Each section explores the links between home, health and happiness, drawing on environmental research and neuroscience while making practical suggestions for bringing the natural world into your home.Bring nature indoors with flowers and plants, rediscover the innate pleasure of real fires and fresh air, and learn how to improve your mood and sleep patterns with dynamic light. Create a space filled with natural elements, patterns, nature's colours, fabrics and textures that lift your mood; find out why natural sounds and water are soothing; and learn how to make small changes that will inspire, invigorate and enrich your relationship with the natural world.'As best-selling author and designer, Sally Coulthard, reveals in this guide, creating a 'biophilic home' can have a huge impact on your wellbeing; improving your mood and encouraging healthier sleep patterns...Be it plants, materials, colour or light, it's enlightening to see how small changes can make a big difference, while deepening your respect and correlation to the natural world.' FORBES Magazine'How to embrace the natural world by transforming your interior spaces with specific materials, colours, views and sounds.' Gardens Illustrated'Humans are mammals, programmed over millennia to respond to the natural world. We may be able to live and work in man-made environments most of the time. But according to a new movement of "biophilic" designers and enthusiasts, we are not thriving...writer Sally Coulthard likens it to the practice of keeping animals in captivity, in surroundings ill-suited to their needs. "We live in a world that is fundamentally mismatched to our evolutionary adaptation - we don't see, hear and feel the things that we are programmed to respond to," she writes.' Financial Times'In this beautifully illustrated hardback, Coulthard explores the many benefits of biophilic design, drawing on environmental and neuroscientific research to uncover the links between home, health and happiness. A fascinating and uplifting read that looks at the science behind feel good furnishings.'The Independent'Never before has the need been greater for being more connected with the natural world, as more and more of us spend longer periods in our own homes. Divided into eight chapters covering key elements for the 'biophilic home', including materials, views, colour and natural light, the book explores the links between home, health and happiness. Drawing on environmental research and neuroscience, Sally makes practical suggestions for bringing the natural world into our homes, positively impacting cognitive function, psychological health and general well-being.' The Lifestyle Editor'...bestselling author Sally Coulthard picks out...the easiest ways we can bring nature indoors' Town and Country House magazine
Biophilic Cities for an Urban Century: Why nature is essential for the success of cities
by Timothy Beatley Robert McDonaldThis book argues that, paradoxically, at their moment of triumph and fastest growth, cities need nature more than ever. Only if our urban world is full of biophilic cities will the coming urban century truly succeed. Cities are quintessentially human, the perfect forum for interaction, and we are entering what could justly be called the urban century, the fastest period of urban growth in human history. Yet a growing body of scientific literature shows that the constant interaction, the hyper-connectedness, of cities leads to an urban psychological penalty. Nature in cities can be solution to this dilemma, allowing us to have all the benefits of our urban, connected world yet also have that urban home be a place where humanity can thrive. This book presents best practices and case studies from biophilic design, showing how cities around the world are beginning to incorporate nature into their urban fabric. It will be a valuable resource for scholars and professionals working in the area of sustainable cities.
Biophilic Cities: Integrating Nature into Urban Design and Planning (Cities And The Global Politics Of The Environment Ser.)
by Timothy BeatleyTim Beatley has long been a leader in advocating for the "greening" of cities. But too often, he notes, urban greening efforts focus on everything except nature, emphasizing such elements as public transit, renewable energy production, and energy efficient building systems. While these are important aspects of reimagining urban living, they are not enough, says Beatley. We must remember that human beings have an innate need to connect with the natural world (the biophilia hypothesis). And any vision of a sustainable urban future must place its focus squarely on nature, on the presence, conservation, and celebration of the actual green features and natural life forms. A biophilic city is more than simply a biodiverse city, says Beatley. It is a place that learns from nature and emulates natural systems, incorporates natural forms and images into its buildings and cityscapes, and designs and plans in conjunction with nature. A biophilic city cherishes the natural features that already exist but also works to restore and repair what has been lost or degraded. In Biophilic Cities Beatley not only outlines the essential elements of a biophilic city, but provides examples and stories about cities that have successfully integrated biophilic elements--from the building to the regional level--around the world. From urban ecological networks and connected systems of urban greenspace, to green rooftops and green walls and sidewalk gardens, Beatley reviews the emerging practice of biophilic urban design and planning, and tells many compelling stories of individuals and groups working hard to transform cities from grey and lifeless to green and biodiverse.
Biophilic Connections and Environmental Encounters in the Urban Age: Frameworks and Interdisciplinary Practice in the Built Environment
by Richard Coles Sandra CostaBiophilic Connections and Environmental Encounters in the Urban Age takes a multi-disciplinary approach, drawing on the authors’ wide range of experience, to provide a greater understanding of the different dimensions of environmental engagement. It considers the ways that we interact with our environments, presenting a comprehensive account of how people negotiate and use the urban landscape. Set within current debates concerning urban futures, societal issues, sustainable cities, health and well-being, the book explores our innate need for contact with the natural world through biophilic design thinking to expand our knowledge base and promote a wider understanding of the importance of these interactions on our collective well-being. It responds to questions such as, what are the urban qualities that support our well-being? As an urbanised society what are the environmental determinants that promote healthy and satisfying lifestyles? Beginning with an overview of concepts relating to biophilia and environmental engagement, it moves through current theory and practice, different pathways and their characteristics, before presenting real world examples and applications through illustrated case studies in different world situations. With a particular focus on the experience of individuals, the book is essential reading for students, researchers, and practitioners of architecture, landscape architecture, urban planning, design and health sciences, interested in the future of our cities and the importance of green spaces.
Biophilic Design
by Stephen R. Kellert Martin Mador Judith Heerwagen"When nature inspires our architecture-not just how it looks but how buildings and communities actually function-we will have made great strides as a society. Biophilic Design provides us with tremendous insight into the 'why,' then builds us a road map for what is sure to be the next great design journey of our times."-Rick Fedrizzi, President, CEO and Founding Chairman, U.S. Green Building Council"Having seen firsthand in my company the power of biomimicry to stimulate a wellspring of profitable innovation, I can say unequivocably that biophilic design is the real deal. Kellert, Heerwagen, and Mador have compiled the wisdom of world-renowned experts to produce this exquisite book; it is must reading for scientists, philosophers, engineers, architects and designers, and-most especially-businesspeople. Anyone looking for the key to a new type of prosperity that respects the earth should start here."-Ray C. Anderson, founder and Chair, Interface, Inc.The groundbreaking guide to the emerging practice of biophilic designThis book offers a paradigm shift in how we design and build our buildings and our communities, one that recognizes that the positive experience of natural systems and processes in our buildings and constructed landscapes is critical to human health, performance, and well-being. Biophilic design is about humanity's place in nature and the natural world's place in human society, where mutuality, respect, and enriching relationships can and should exist at all levels and should emerge as the norm rather than the exception.Written for architects, landscape architects, planners,developers, environmental designers, as well as building owners, Biophilic Design: The Theory, Science, and Practice of Bringing Buildings to Life is a guide to the theory, science, and practice of biophilic design. Twenty-three original and timely essays by world-renowned scientists, designers, and practitioners, including Edward O. Wilson, Howard Frumkin, David Orr, Grant Hildebrand, Stephen Kieran, Tim Beatley, Jonathan Rose, Janine Benyus, Roger Ulrich, Bert Gregory, Robert Berkebile, William Browning, and Vivian Loftness, among others, address:*The basic concepts of biophilia, its expression in the built environment, and how biophilic design connects to human biology, evolution, and development.*The science and benefits of biophilic design on human health, childhood development, healthcare, and more.*The practice of biophilic design-how to implement biophilic design strategies to create buildings that connect people with nature and provide comfortable and productive places for people, in which they can live, work, and study.Biophilic design at any scale-from buildings to cities-begins with a few simple questions: How does the built environment affect the natural environment? How will nature affect human experience and aspiration? Most of all, how can we achieve sustained and reciprocal benefits between the two?This prescient, groundbreaking book provides the answers.
Biophilic Urbanism: Designing Resilient Communities for the Future
by Phillip James TabbBiophilic Urbanism provides readers with the tools to create more nature-based urban environments that are climate positive, sustainable, and healthy. The principles of biophilia are intended to support appreciation and direct engagement with nature, to responsibly utilize on-site natural resources, and to plan according to climatic conditions and local ecological processes. It seeks to create resilient and equitable human places capable of providing critical life-support functions and a strong sense of community, and to foster experiences that raise the human spirit creating a sense of awe. Twenty-five pattern attributes are defined and explored, each of which contributes to these goals. Because of the dire necessity to respond to the COVID-19 pandemic, Biophilic Urbanism includes discussion of our need for connections, both to nature and one another, and the physical characteristics of cities and buildings relative to the contagious qualities of the air-borne virus. Case studies, found throughout the world, are presented illustrating detailed biophilic planning and design strategies. The book will be of use to practitioners and students in the fields of natural and social sciences, behavioral science and psychology, environmental engineering, health and wellness professionals, architecture, landscape architecture, interior architecture, and planning.
Biophilic and Bioclimatic Architecture: Analytical Therapy for the Next Generation of Passive Sustainable Architecture
by Amjad AlmusaedBiophilic and Bioclimatic Architecture is a guide to innovative architectural design for architects, engineers and other specialists who are working with biophilic and bioclimatic architectural concepts. Biophilic and Bioclimatic Architecture has three parts: * Part I focuses on the relationship between architecture and human needs and the creation process, demonstrating the meaning of architectural value in architectural hypothesis. * Part II opens the way towards a new understanding of biophilic architecture as a response to the negative actions of humans and the negative effects of using natural resources. * Part III shows the benefits of combining the effects of the climate with the notion of human comfort in bioclimatic architecture.
Biophotoelectrochemistry: From Bioelectrochemistry to Biophotovoltaics (Advances in Biochemical Engineering/Biotechnology #158)
by Lars J.C. JeukenThis book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science.Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification.In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.
Biophotonics: Concepts to Applications (Graduate Texts in Physics)
by Gerd KeiserThis book introduces senior-level and postgraduate students to the principles and applications of biophotonics. It also serves as a valuable reference resource or as a short-course textbook for practicing physicians, clinicians, biomedical researchers, healthcare professionals, and biomedical engineers and technicians dealing with the design, development, and application of photonics components and instrumentation to biophotonics issues. The topics include the fundamentals of optics and photonics, the optical properties of biological tissues, light-tissue interactions, microscopy for visualizing tissue components, spectroscopy for optically analyzing the properties of tissue, and optical biomedical imaging. It also describes tools and techniques such as laser and LED optical sources, photodetectors, optical fibers, bioluminescent probes for labeling cells, optical-based biosensors, surface plasmon resonance, and lab-on-a-chip technologies. Among the applications are optical coherence tomography (OCT), optical imaging modalities, photodynamic therapy (PDT), photobiostimulation or low-level light therapy (LLLT), diverse microscopic and spectroscopic techniques, tissue characterization, laser tissue ablation, optical trapping, and optogenetics. Worked examples further explain the material and how it can be applied to practical designs, and the homework problems help test readers' understanding of the text.
Biophotonics: Concepts to Applications (Graduate Texts in Physics)
by Gerd KeiserThis book introduces senior-level and postgraduate students to the principles and applications of biophotonics. It also serves as a valuable reference resource or as a short-course textbook for practicing physicians, clinicians, biomedical researchers, healthcare professionals, and biomedical engineers and technicians dealing with the design, development, and application of photonics components and instrumentation to biophotonics issues. The topics include the fundamentals of optics and photonics, the optical properties of biological tissues, light-tissue interactions, microscopy for visualizing tissue components, spectroscopy for optically analyzing the properties of tissue, and optical biomedical imaging. It also describes tools and techniques such as laser and LED optical sources, photodetectors, optical fibers, bioluminescent probes for labeling cells, optical-based biosensors, surface plasmon resonance, and lab-on-a-chip technologies. Among the applications are optical coherence tomography (OCT), optical imaging modalities, photodynamic therapy (PDT), photobiostimulation or low-level light therapy (LLLT), diverse microscopic and spectroscopic techniques, tissue characterization, laser tissue ablation, optical trapping, and optogenetics. Worked examples further explain the material and how it can be applied to practical designs, and the homework problems help test readers’ understanding of the text.This second edition provides updates as follows:1) Updated references in each chapter with recent review papers, tutorials, and generic research results.2) New sections in Chap. 3 addressing tapered fibers for sensors, biocompatibility issues of optical fibers, and concepts of implantable fibers.3) Updates in Chaps. 4 and 5 on optical sources and photodetectors discussing fiber-based sources, silicon photomultipliers, and high-speed cameras for biosensing.4): Sections on improvements in microscopy, imaging, spectroscopy, and sensing in Chapters 7–10. 5) New biophotonic application techniques in Chap. 11 will include optogenetic advances, smart phones for imaging, wearable biophotonic sensors, and robotic surgery and light therapy.
Biophysical Applications of Satellite Remote Sensing (Springer Remote Sensing/Photogrammetry)
by Jonathan M. HanesA variety of biophysical applications (e. g. leaf area index and gross primary productivity) have been derived from measurements of the Earth system obtained remotely by NASA's MODIS sensors and other satellite platforms. In Biophysical Applications of Satellite Remote Sensing, the authors describe major applications of satellite remote sensing for studying Earth's biophysical phenomena. The focus of the book lies on the broad palette of specific applications (metrics) of biophysical activity derived using satellite remote sensing. With in-depth discussions of satellite-derived biophysical metrics that focus specifically on theory, methodology, validation, major findings, and directions of future research, this book provides an excellent resource for remote sensing specialists, ecologists, geographers, biologists, climatologists, and environmental scientists.
Biophysical Characterization of Functional Peptides (Springer Protocols Handbooks)
by Vibin RamakrishnanThis protocol book presents reproducible and step-by-step procedures for the peptide synthesis, their characterization and applications. The volume includes an introductory section on in silico modelling of new peptide molecules, Molecular Dynamics Simulations, Docking, Electrostatic fingerprinting of peptides, and other modelling tools for peptide designing and optimization. Further, it covers protocols for the solid phase peptide synthesis, chromatographic and mass spectrometric characterization of peptides. Importantly, it covers methods for biophysical characterizations of peptides for their potential applications as drug delivery vehicles, peptide nano-assembly, bionanocatalysis, protein aggregation diseases, and peptide-based anti-bacterial.
Biophysical Chemistry
by Dagmar Klostermeier Markus G. RudolphBiophysical Chemistry explores the concepts of physical chemistry and molecular structure that underlie biochemical processes. Ideally suited for undergradate students and scientists with backgrounds in physics, chemistry or biology, it is also equally accessible to students and scientists in related fields as the book concisely describes the fundamental aspects of biophysical chemistry, and puts them into a biochemical context. The book is organized in four parts, covering thermodynamics, kinetics, molecular structure and stability, and biophysical methods. Cross-references within and between these parts emphasize common themes and highlight recurrent principles. End of chapter problems illustrate the main points explored and their relevance for biochemistry, enabling students to apply their knowledge and to transfer it to laboratory projects. Features: Connects principles of physical chemistry to biochemistry Emphasizes the role of organic reactions as tools for modification and manipulation of biomolecules Includes a comprehensive section on the theory of modern biophysical methods and their applications
Biophysical Chemistry
by Dagmar Klostermeier Markus G. RudolphBiophysical Chemistry explores the concepts of physical chemistry and molecular structure that underlie biochemical processes. Ideally suited for undergraduate students and scientists with backgrounds in physics, chemistry, or biology, it is also equally accessible to students and scientists in related fields as the book concisely describes the fundamental aspects of biophysical chemistry and puts them into a biochemical context.This second edition has been fully updated throughout with novel techniques, with a new chapter on advances in cryo-electron microscopy and exciting new content throughout on big data techniques, structural bioinformatics, systems biology and interaction networks, and artificial intelligence and machine learning.The book is organized in four parts, covering thermodynamics, kinetics, molecular structure and stability, and biophysical methods. Cross-references within and between these parts emphasize common themes and highlight recurrent principles. End of chapter problems illustrate the main points explored and their relevance for biochemistry, enabling students to apply their knowledge and to transfer it to laboratory projects.Key Features: Connects principles of physical chemistry to biochemistry Emphasizes the role of organic reactions as tools for modification and manipulation of biomolecules Includes a comprehensive section on the theory of modern biophysical methods and their applications