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Antipsychotic Trials in Schizophrenia
by Jeffrey A. Lieberman T. Scott StroupAntipsychotic medications are a key treatment for schizophrenia and sales of antipsychotic drugs approach $20 billion per year, with fierce marketing between the makers of the drugs. The U.S. National Institute of Mental Health sponsored the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project to provide independent information about the comparative effectiveness of medications. CATIE was the largest, longest and most comprehensive study of schizophrenia to date. Conducted under rigorous double-blind conditions, Antipsychotic Trials in Schizophrenia presents the definitive archival results of this landmark study. The core of the book consists of chapters focused on specific outcomes that set the CATIE findings in a wider context. Also included are chapters on the design, statistical analyses and implications for researchers, clinicians and policy makers. Psychiatrists, psychiatric researchers, mental health policy makers and those working in pharmaceutical companies will all find this to be essential reading.
Antipsychotic Trials in Schizophrenia
by T. Scott Stroup Jeffrey A. LiebermanAntipsychotic medications are a key treatment for schizophrenia, and sales of antipsychotic drugs approach $20 billion per year, with fierce marketing between the makers of the drugs.
Antipsychotics
by Stephen M. Stahl Laurence MignonRelying upon the best-selling third edition of Stahl's Essential Psychopharmacology, Dr Stephen M. Stahl has revised chapters covering antipsychotics and mood stabilizers for this edition. More than one-third longer than the previous edition it is essential reading for professionals treating psychosis and students learning the mechanisms of drug reactions. It includes advances in neurobiology and recent clinical developments to explain the concepts underlying drug treatment of psychiatric disorders. The fully revised text is complemented by many new illustrations and enhanced to reflect new knowledge and topics covered in the previous edition. Intended as a primer text covering all aspects of treatment for psychosis and related conditions, this concise volume can nevertheless be read cover to cover by experts and novices alike. Accreditation and Credit Designation Statements The Neuroscience Education Institute is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The Neuroscience Education Institute designates this educational activity for a maximum of 90. 0 AMA PRA Category 1 Credits(tm). Physicians should only claim credit commensurate with the extent of their participation in the activity. Sponsorship Information Sponsored by Neuroscience Education Institute Support This activity is supported solely by the sponsor. Neither the Neuroscience Education Institute nor Stephen M. Stahl, MD, PhD has received any funds or grants in support of this educational activity.
Antiracist by Design: Reimagining Applied Behavioral Science
by Crystal C. Hall Mindy HernandezHow to confront the challenge of creating antiracist behavioral design—and how to successfully implement the solutions.Behavioral science has been celebrated as a field whose insights can design a better world, but its color-blind approach has perpetuated unjust systems. With over three decades of collective experience at the forefront of applied behavioral science, authors Hall and Hernandez expose the consequences of this failure and the dangers of inaction. While our hesitancy is understandable—applied behavioral science alone won&’t dismantle structural racism—we&’ve confused limitations with powerlessness. This book provides a call to action.Antiracist By Design provides the tools and a roadmap to an antiracist approach to applied behavioral science, including a step-by-step guide to reimagined behavioral design processes, &“fan fiction&” with antiracist makeovers to classic studies, and a revised behavioral map template that prompts users to consider systemic barriers. Written for anyone who wants to make the world a more just place, Hall and Hernandez use scholarly research alongside accessible stories (from Mozart and Chris Rock to the TV show Insecure) to illuminate ways we can drive racial justice forward. Everyone from scholars to students to NGO program designers, will benefit from these renovated best practices.
Antiseizure Medication Interactions: A Clinical Guide
by Philip N. PatsalosThis significantly revised fourth edition provides a practically orientated guide to interactions associated with antiseizure medications. It describes pharmacokinetic and pharmacodynamic antiseizure medication (ASM) interactions, including details of the magnitude and mechanism of interactions, and also of drug combinations that are not associated with interactions and therefore can be co-prescribed without undue concern. Presented in alphabetical order and by drug class, drug interactions that occur between ASMs and also between ASMs and non- ASMs are described in three sections: Drug interactions between ASMs; Drug interactions between ASMs and non- ASM Drugs: Interactions affecting ASMs; Drug interactions between ASMs and non ASM Drugs: Interactions affected by ASMs. The latest data on all drug interactions is presented. New agents discussed include cannabidiol, cenobamate, everolimus and fenfluramine,. Antiseizure Medication Interactions: A Clinical Guide, 4th Edition concisely presents the most recent developments and data available on the topic. Therefore, enabling physicians and allied health professionals to make more rational choices when ASM polytherapy regimens are required. It will be of interest to medical professionals in disciplines including neurology, psychiatry and pediatrics.
Antisense RNA Design, Delivery, and Analysis (Methods in Molecular Biology #2434)
by Virginia Arechavala-Gomeza Alejandro GarantoThis open access volume gathers a variety of models, delivery systems, and approaches that can be used to assess RNA technology for exploiting antisense as a therapeutic intervention. Beginning with a section on the design of antisense technology and their delivery, the book continues by covering model systems developed to evaluate efficacy, both in vivo and in vitro, as well as methods to evaluate preclinically the toxicity associated with these new potential drugs, and intellectual property considerations. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Antisense RNA Design, Delivery, and Analysis provides basic knowledge and a large collection of methods to facilitate the work of newcomers to this vibrant and expanding field. This book was conceived thanks to the network DARTER (Delivery of Antisense RNA Therapeutics). DARTER is funded by the EU Cooperation of Science and Technology (COST), which aims to enhance interaction and collaborations between researchers in Europe and other countries.
Antisocial Behavior
by Benjamin B. WolmanAntisocial behavior takes on many forms, from rebellious teens with green hair and pierced skin to the truly dangerous homicidal individuals whose horrible stories fill our newspapers. Parents worry about their children as they are exposed to the heatedclimate of violence in contemporary society, a time of decaying morals and values.The rise in sociopathic behavior among adults and children, whether in tense inner cities or in tranquil suburban and rural settings, is masterfully chronicled by Dr. Benjamin B. Wolman, a leading psychologist and noted national expert who has studied these trends for over half a century. "There is a growing incidence of sociopathic antisocial behavior . . . coupled with an attitude of moral apathy," Dr. Wolman asserts. He cites international statistics pointing to a showdown between dangerous individuals-the violent, the charming, and the passive-and the societies that create them.How has the spread of democratic ideals actually increased the potential for antisocial behavior? What social and cultural factors must be changed if free societies are to reduce this alarming trend?Rather than simply complain about the problem, Dr. Wolman examines the familial and societal causes, and proposes clear-cut solutions to the problem-including radical changes to our educational system and the mass media.
Antisocial Behavior and Mental Health Problems: Explanatory Factors in Childhood and Adolescence
by Rolf Loeber David P. Farrington Magda Stouthamer-Loeber Welmoet B. Van KammenEpidemiological surveys have provided key information about the prevalence and degree of seriousness at different ages of a wide array of problem behaviors such as delinquency, substance use, early sexual involvement, and mental health disorders. Knowledge of the extent of these problems and changes in their course over time is important. In its absence, interventions and health planning in general can be difficult. Understanding which risk and protective factors are relevant to which problem behaviors is also essential for the formulation of theories that constitute the basis of intervention. This book draws on the results of the major Pittsburgh Youth Study complemented by follow-up tracking of juvenile court records for more than six years, to address the following questions: *What is the prevalence and age of onset of delinquency, substance use, and early sexual behavior for three samples of boys age 8, 11, and 14? What are the average mental health problems for these ages? How strong are the relationships among these problem behaviors in each of the samples? *Which variables best explain individual differences among the boys in their manifestations of delinquency, substance use, early sexual behavior, and mental health problems? To what extent do explanatory factors vary with age? How accurately can boys with different outcomes be identified by risk scores based on hierarchical multiple regressions? *To what extent are explanatory factors associated with one outcome that are also associated with other outcomes? Are explanatory factors that are especially characteristic of a multiproblem group of boys--who display many different problem behaviors--different from explanatory factors associated with boys with few problems? *Do the results fit a general theory of juvenile problem behaviors, or is a differentiated theory more applicable?
Antisocial, Narcissistic, and Borderline Personality Disorders: A New Conceptualization of Development, Reinforcement, Expression, and Treatment
by Daniel J. FoxThis book provides a framework for scholars and clinicians to develop a comprehensive and dynamic understanding of antisocial, narcissistic, and borderline personality disorders, by seeing personality as a dual, as opposed to a singular, construct. Converging the two separate research and clinical diagnostic systems into a wholistic model designed to reach reliable and valid diagnostic conclusions, the text examines adaptive and maladaptive personality development and expression, while addressing the interpersonal system that keeps the pathology from extinguishing. Each chapter will discuss core and surface content, origin and symptom manifestation, system and pathology perpetuation, and online behavior expression, concluding with practical guidance on treatment success and effective approaches. Seasoned and tyro researchers and clinicians will be challenged to explore the utility of the DSM-5 alternative model of personality disorders and apply it to further the understanding of these complex, and often destructive, disorders.
The Antisocial Personalities
by David T. LykkenThis volume presents a scholarly analysis of psychopathic and sociopathic personalities and the conditions that give rise to them. In so doing, it offers a coherent theoretical and developmental analysis of socialization and its vicissitudes, and of the role played in socialization by the crime-relevant genetic traits of the child and the skills and limitations of the primary socializing agents, the parents. This volume also describes how American psychiatry's (DSM-IV) category of "Antisocial Personality Disorder" is heterogeneous and fails to document some of the more interesting and notorious psychopaths of our era. The author also shows why the antinomic formula "Nature vs. Nurture" should be revised to "Nature via Nurture" and reviews the evidence for the heritability of crime-relevant traits. One of these traits -- fearlessness -- seems to be one basis for the primary psychopathy and the author argues that the primary psychopath and the hero may be twigs on the same genetic branch. But crime -- the failure of socialization -- is rare among traditional peoples still living in the extended-family environment in which our common ancestors lived and to which our species is evolutionarily adapted. The author demonstrates that the sharp rise in crime and violence in the United States since the 1960s can be attributed to the coeval increase in divorce and illegitimacy which has left millions of fatherless children to be reared by over-burdened, often immature or sociopathic single mothers. The genus sociopathic personality includes those persons whose failure of socialization can be attributed largely to incompetent or indifferent rearing. Two generalizations supported by modern behavior genetic research are that most psychological traits have strong genetic roots and show little lasting influence of the rearing environment. This book demonstrates that the important trait of socialization is an exception. Although traits that obstruct or facilitate socialization tend to obey these rules, socialization itself is only weakly heritable; this is because modern American society displays such enormous variance in the relevant environmental factors, mainly in parental competence. Moreover, parental incompetence that produces sociopathy in one child is likely to have the same result with any siblings. This book argues that sociopathy contributes far more to crime and violence than psychopathy because sociopaths are much more numerous and because sociopathy is a familial trait for both genetic and environmental reasons. With a provocative thesis and an engaging style, this book will be of principal interest to clinical, personality, forensic, and developmental psychologists and their students, as well as to psychiatrists and criminologists.
Antisoziales: Eine Kurzanalyse aus der Perspektive der „Dunklen Triade“ (essentials)
by Karin MeyerNarzissmus gilt auf Führungsetagen als ein verbreitetes Phänomen, das dort im Vergleich zur restlichen Bevölkerung überdurchschnittlich stark repräsentiert ist. Weiterhin weisen jüngere Nachwuchs(führungs-)kräfte deutlich höhere Narzissmus-Ausprägungen auf als dies in den älteren Generationen bislang der Fall war. Gleichzeitig treten Verhaltenszüge der Dunklen Triade (Narzissmus, Machiavellismus und Psychopathie) meist nicht isoliert, sondern in Kombination auf. Unternehmen sollten aus diesem Grund schon heute ihre Personalauswahl, -führung und -entwicklung überdenken. Beleuchtet werden daher Merkmale und Verhaltensmuster rücksichtsloser Personen der Dunklen Triade – ebenso mögliche Ansätze zur Intervention und Prävention.
Antonino Ferro: A Contemporary Introduction (Routledge Introductions to Contemporary Psychoanalysis)
by Robert SnellThis book provides a clear, thorough, and accessible introduction to the work of Antonino Ferro and draws on the clinical vignettes that punctuate his writings to show how Ferro has built on Bion’s revolutionary achievements to develop a distinctive, game-changing version of field theory in psychoanalysis.The book clarifies the phenomenological insight that the analyst and the patient together generate an ever-evolving, intersubjective field. Rather than the supposed psychology of the individual, it is this populous and multidimensional field, a co-created ‘in-between’ rich in characters and stories, that is to be explored and elaborated. The primary points of access to this new ‘multiverse’ are dream, reverie, metaphor, and imagination. A radical Negative Capability is called for, not least to help dissolve co-constructed ‘bastions’ obstructing the field’s expansion. The book sketches out the Italian and international context in which Ferro developed his thinking and addresses some key critical questions. It concludes that Ferro’s life’s work, which marries theoretical rigour with a revitalising increase in playfulness and freedom of response, is a transformational force within psychoanalysis and a major catalyst in its evolution.This important volume is rewarding reading for beginning and seasoned analysts alike, as well as for psychotherapists, counsellors, humanities scholars, and anyone interested in psychoanalysis.
Anwendung des Genome Editing in der somatischen Gentherapie: Eine Einführung (essentials)
by Boris Fehse Ulrike Abramowski-MockDieses essential gibt einen Überblick über Grundlagen sowie Chancen und Risiken der Gentherapie, mit besonderem Fokus auf das Genome Editing. Es werden aktuelle und zukünftige klinische Anwendungen der neuen, mit vielen Hoffnungen, aber auch Ängsten verbundenen Technologien diskutiert.
Anxiety: A Philosophical Guide (Moral Psychology Of The Emotions Ser.)
by Samir ChopraHow philosophy can teach us to be less anxious about being anxious by understanding that it&’s an essential part of being humanToday, anxiety is usually thought of as a pathology, the most diagnosed and medicated of all psychological disorders. But anxiety isn&’t always or only a medical condition. Indeed, many philosophers argue that anxiety is a normal, even essential, part of being human, and that coming to terms with this fact is potentially transformative, allowing us to live more meaningful lives by giving us a richer understanding of ourselves. In Anxiety, Samir Chopra explores valuable insights about anxiety offered by ancient and modern philosophies—Buddhism, existentialism, psychoanalysis, and critical theory. Blending memoir and philosophy, he also tells how serious anxiety has affected his own life—and how philosophy has helped him cope with it.Chopra shows that many philosophers—including the Buddha, Kierkegaard, Nietzsche, Freud, and Heidegger—have viewed anxiety as an inevitable human response to existence: to be is to be anxious. Drawing on Karl Marx and Herbert Marcuse, Chopra examines how poverty and other material conditions can make anxiety worse, but he emphasizes that not even the rich can escape it. Nor can the medicated. Inseparable from the human condition, anxiety is indispensable for grasping it. Philosophy may not be able to cure anxiety but, by leading us to greater self-knowledge and self-acceptance, it may be able to make us less anxious about being anxious.Personal, poignant, and hopeful, Anxiety is a book for anyone who is curious about rethinking anxiety and learning why it might be a source not only of suffering but of insight.
Anxiety: The Cognitive Perspective (Essays in Cognitive Psychology)
by Michael W. EysenckTheorists are increasingly arguing that it is fruitful to approach anxiety from the cognitive perspective, and the empirical evidence supports that contention. The cognitive perspective is also adopted in this book, but the approach represents a development and extension of earlier ones. For example, most previous theories and research have been based on anxiety either in clinical or in normal groups. In contrast, one of the central themes of this book is that there are great advantages to be gained from a joint consideration of clinical and normal anxiety.Another theme of this book is that it is of major importance to establish whether or not there is a cognitive vulnerability factor which is associated with at least some forms of clinical anxiety. It is argued (with supporting evidence) that there is a latent cognitive vulnerability factor for generalized anxiety disorder which manifests itself under stressful conditions. This vulnerability factor is characterized by hypervigilance, and is found predominantly in normals high in the personality dimension of trait anxiety.The scope of the book extends to the effects of anxiety on performance and to the phenomenon of worry, which is regarded as the cognitive component of anxiety. In both cases, a new theoretical framework is presented.
Anxiety: A Practical Guide to Understanding and Overcoming Anxiety Disorder
by Joshua FletcherDo you suffer from anxiety and panic? So did Joshua Fletcher, the author of the self-published bestseller ANXIETY: PANICKING ABOUT PANIC - but he treated his own condition successfully, went back to school, became a counsellor and emerged as one of the country's leading experts. ANXIETY: PRACTICAL ABOUT PANIC is a complete, easy to read and hugely practical book about anxiety from someone who knows how to recover and live your life to the full - and will show you how. Concentrating on the actions that you can take to alleviate and overcome your worries, this book is all about you and what you need to do to improve your life.
Anxiety: A Practical Guide to Understanding and Overcoming Anxiety Disorder
by Joshua FletcherDo you suffer from anxiety and panic? So did Joshua Fletcher, the author of the self-published bestseller ANXIETY: PANICKING ABOUT PANIC - but he treated his own condition successfully, went back to school, became a counsellor and emerged as one of the country's leading experts. ANXIETY: PRACTICAL ABOUT PANIC is a complete, easy to read and hugely practical book about anxiety from someone who knows how to recover and live your life to the full - and will show you how. Concentrating on the actions that you can take to alleviate and overcome your worries, this book is all about you and what you need to do to improve your life.
Anxiety: A Practical Guide to Understanding and Overcoming Anxiety Disorder
by Joshua FletcherDo you suffer from anxiety and panic? So did Joshua Fletcher, the author of the self-published bestseller ANXIETY: PANICKING ABOUT PANIC - but he treated his own condition successfully, went back to school, became a counsellor and emerged as one of the country's leading experts. ANXIETY: PRACTICAL ABOUT PANIC is a complete, easy to read and hugely practical book about anxiety from someone who knows how to recover and live your life to the full - and will show you how. Concentrating on the actions that you can take to alleviate and overcome your worries, this book is all about you and what you need to do to improve your life.(P) 2019 Hodder & Stoughton Ltd
Anxiety: Recent Developments In Cognitive, Psychophysiological And Health Research (Series in Health Psychology and Behavioral Medicine)
by Donald G. Forgays Tytus Sosnowski Kazimierz WrzesniewskiFirst published in 1992. Routledge is an imprint of Taylor & Francis, an informa company.
Anxiety: A Self-Help Guide to Feeling Better (50 Things Ser.)
by Wendy GreenIn Anxiety: A Self-Help Guide to Feeling Better, Wendy Green explains how psychological, genetic and dietary factors can contribute to anxiety and offers practical advice and a holistic approach to help you deal with the symptoms, including simple dietary and lifestyle changes and DIY complementary therapies.
Anxiety: A Short History
by Allan V. HorwitzMore people today report feeling anxious than ever before—even while living in relatively safe and prosperous modern societies. Almost one in five people experiences an anxiety disorder each year, and more than a quarter of the population admits to an anxiety condition at some point in their lives. Here Allan V. Horwitz, a sociologist of mental illness and mental health, narrates how this condition has been experienced, understood, and treated through the ages—from Hippocrates, through Freud, to today. Anxiety is rooted in an ancient part of the brain, and our ability to be anxious is inherited from species far more ancient than humans. Anxiety is often adaptive: it enables us to respond to threats. But when normal fear yields to what psychiatry categorizes as anxiety disorders, it becomes maladaptive. As Horwitz explores the history and multiple identities of anxiety—melancholia, nerves, neuroses, phobias, and so on—it becomes clear that every age has had its own anxieties and that culture plays a role in shaping how anxiety is expressed. -- Peter Conrad, Brandeis University
Anxiety: A Short History (Johns Hopkins Biographies of Disease)
by Allan V. HorwitzFears, phobias, neuroses, and anxiety disorders from ancient times to the present.More people today report feeling anxious than ever before—even while living in relatively safe and prosperous modern societies. Almost one in five people experiences an anxiety disorder each year, and more than a quarter of the population admits to an anxiety condition at some point in their lives. Here Allan V. Horwitz, a sociologist of mental illness and mental health, narrates how this condition has been experienced, understood, and treated through the ages—from Hippocrates, through Freud, to today.Anxiety is rooted in an ancient part of the brain, and our ability to be anxious is inherited from species far more ancient than humans. Anxiety is often adaptive: it enables us to respond to threats. But when normal fear yields to what psychiatry categorizes as anxiety disorders, it becomes maladaptive. As Horwitz explores the history and multiple identities of anxiety—melancholia, nerves, neuroses, phobias, and so on—it becomes clear that every age has had its own anxieties and that culture plays a role in shaping how anxiety is expressed.
Anxiety: How to Calm Your Thoughts and Quieten Your Mind
by Debbi MarcoLife’s journey is not always smooth sailing, but there are ways of charting your own course. This compact book is packed with simple but effective tips and advice to ease your mind in times of turbulence, and help you find calm in every situation.
Anxiety: Finding Comfort and Reassurance from God (LifeGuide Bible Studies)
by Skip McDonaldShallow breathing or even a feeling that you can't breathe. Constant negative thoughts. Inability to focus.®
Anxiety
by Adams MediaIf you or a family member is suffering from anxiety, you may feel overwhelmed by the challenges associated with this condition. The Everything® Healthy Living Series is here to help. These concise, thoughtful guides offer the expert advice and the latest medical information you need to manage your pain and lead a healthy life.Inside you’ll find expert advice and helpful tips on understanding anxiety, seeking help from therapist and support groups, finding the best medications and treatments, and thoughtful advice on helping family and friends understand your condition. Living with depression can be challenging, but with the right guidance you can live a happy and healthy life.