- Table View
- List View
Clinical Applications of Cardiac CT
by Massimo Midiri Filippo Cademartiri Giancarlo CasoloDuring the past few years, cardiac CT (CCT) has acquired an increasingly important role as a noninvasive imaging method that allows assessment of coronary heart disease from both the morphological and the functional standpoint. It is quickly becoming a primary clinical tool for the evaluation and follow-up of various conditions related to the heart and great vessels and is providing valuable insights into the natural history of atherosclerosis. The rapid advances in CCT technology, the advent of new clinical applications, and the acquisition of data on prognostic value are just some of the reasons for the publication of this new edition of Clinical Applications of Cardiac CT, little more than 3 years after the first edition appeared. The text has been extensively revised and updated to reflect current knowledge and practice, and the structure and layout of the educational content have also been improved. The imaging targets, semeiology, technique, and clinical applications of CCT are all covered in detail, and in addition relevant information is provided on epidemiology, clinical assessment, and the role of other diagnostic modalities. This book will prove an invaluable tool for radiologists and cardiologists alike.
Clinical Applications of Human Anatomy and Physiology for Healthcare Professionals
by Jassin JouriaAnatomy and Physiology is effectively a broad introductory course that requires the student to devote an enormous amount of effort to understand it on even a basic level. While this necessitates time, it can be streamlined in the early stages of one’s learning so that the student may understand why he or she is required to invest such a large amount of time into learning - Clinical Applications of Human Anatomy & Physiology is the textbook that accomplishes this.°Clinical Applications of Human Anatomy & Physiology is a book that combines both areas of knowledge for a full comprehension of the human body. It is targeted to healthcare students in need of a better understanding of human physiology to combine with their clinical training. The main objective of this book is to elucidate the organization and functioning of the major organs and systems with an emphasis on the applications of this knowledge on the daily clinical routine.°One of the main differences of this textbook that sets it apart from others is that it not only provides the information: it also contextualizes it. Every chapter starts introducing a case study that is related to the content that is going to be approached. At the end of the chapter, there is the conclusion of each case study, which presents the final diagnosis showing every step of the process. This context is essential so that, when the student faces this situation in the real-life clinic he or she will be able to deal with it efficiently. Clinical Applications of Human Anatomy & Physiology also has sections of questions to practice the knowledge that was obtained during the chapter, and the answers to each question are explained so no doubts remain after studying. All of this means that Clinical Applications of Human Anatomy & Physiology is a fully rounded book that combines information and practical applications, as well as questions that help the student to understand and retain all the information in a very efficient and effective way. This book has all the information you need to get started on your journey to learning about the human body.
Clinical Applications of Immunomics (Immunomics Reviews: #2)
by Andras FalusThis is the second volume in a series that will be dedicated to publishing advances in immunomics particularly those focusing on systemic and integrative approaches in basic and clinical immunology, immunoinformatics, and immunologically relevant instrumentation and high-throughput screening methods. Rapid improvement in accessibility to molecular databases as well as availability of high throughput genomic, proteomic, and other 'omics' methodologies are forcing a considerable shift in research and development strategies for biomedicine. Systems biology, a systematic study of complex interactions in biological systems, is currently closely related to the development and application of bioinformatics and biostatistics tools to genomic and proteomic data in clinical immunology, as well. Systems immunology translates achievements of immunological research to medically relevant applications such as diagnosis, prevention, and therapy. Clinical immunomics covers a broad range of diseases and this volume brings together a work representing a spectrum of immunomic applications to showcase key technologies that will shape clinical immunology in the near future. The chapters show examples of immunomics approaches to cancer, autoimmunity, allergy, and primary immunodeficiencies. Key concepts of this volume deal with various combinations of bioinformatics and biostatistics, instrumentation, molecular biology, animal models, and clinical samples for the advancement of clinical immunology.
Clinical Applications of Linguistics to Speech-Language Pathology: A Guide for Clinicians
by Naomi Gurevich Christopher M. GrindrodClinical Applications of Linguistics to Speech-Language Pathology is a practical guide that provides linguistically grounded approaches to clinical practice. It introduces key linguistic disciplines and discusses how they form a basis for assessment and treatment of individuals with communication differences or disorders. Written by experts in linguistics and communication disorders, each chapter provides clinicians with a foundational understanding of linguistics as it applies to spoken and signed languages and underscores the importance of integrating linguistic theories into clinical decision-making. The book is divided into two parts that focus on the applications of linguistics to speech and language differences and disorders in both children and adults. The chapters cover the full range of linguistic domains including phonetics, phonology, morphology, syntax, semantics, pragmatics, and sociolinguistics. Applications to a wide range of populations including childhood apraxia of speech, aphasia, dysarthria, traumatic brain injury and accent modification clients are also discussed. Many chapters include assessment and treatment resources that can be used by practicing clinicians. This highly accessible and comprehensive book is an indispensable resource for practicing speech-language pathologists and other members of the profession, including instructors with minimal exposure to linguistics. It will also be beneficial for students of Linguistics, Speech and Hearing Sciences, and Audiology and Speech Language Pathology who are seeking practical knowledge of the fields.
Clinical Applications of Magnetic Nanoparticles: From Fabrication to Clinical Applications
by Nguyễn T. K. ThanhOffering the latest information in magnetic nanoparticle (MNP) research, this book builds upon the success of the first volume and provides an updated and comprehensive review, from synthesis, characterization, and biofunctionalization to clinical applications of MNPs, including the diagnosis and treatment of cancers. The book captures some of emerging research area which was not available in the first volume. Good Manufacturing Practices and Commercialization of MNPs are also included. This volume, also written by some of the most qualified experts in the field, incorporates new developments in the literature, and continues to bridge the gaps between the different areas in this field.
Clinical Applications of Mass Spectrometry in Biomolecular Analysis: Methods and Protocols (Methods in Molecular Biology #1378)
by Uttam GargThis volume provides stepwise instructions for the analysis of numerous clinically important analytes by mass spectrometry. Mass spectrometry offers clinical laboratory scientists a number of advantages including increased sensitivity and specificity, multiple component analysis, and no need for specialized reagents. The techniques described are a must for the measurement of many clinically relevant analytes in the fields of drug analysis, endocrinology, and inborn errors of metabolism. Each chapter provides a brief introduction about a specified analyte, followed by detailed instructions on the analytical protocol. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and practical, Clinical Applications of Mass Spectrometry in Biomolecular Analysis: Methods and Protocols is a great resource for clinical laboratory scientists who are already using or thinking of bringing mass spectrometry to their laboratories.
Clinical Applications of Mass Spectrometry in Biomolecular Analysis: Methods and Protocols (Methods in Molecular Biology #2546)
by Uttam GargThis updated volume provides stepwise instructions for the analysis of numerous clinically important analytes by mass spectrometry. Mass spectrometry offers clinical laboratory scientists a number of advantages including increased sensitivity and specificity, multiple component analysis, and limited need for specialized reagents. These techniques are essential in laboratory fields including endocrinology, biochemical genetics, drug analysis, proteomics, and pathogen identification. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Clinical Applications of Mass Spectrometry in Biomolecular Analysis: Methods and Protocols, Second Edition is an ideal resource for clinical laboratory scientists who are already using or thinking of bringing mass spectrometry to their laboratories.
Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols (Methods in Molecular Biology #1383)
by Uttam GargThis volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Chapters in the book cover a wide array of topics such as: quantitation of Flecainide, Mexiletine, Propafenone, and Amiodarone in Serum or Plasma; quantitation of total Buprenorphine and Norbuprenorphine in Meconium; quantitation or Carisoprodol and Meprobamate in Urine; and quantitation of Tricyclic Antidepressants in Serum. Each chapter contains a brief introduction to the topic, clinical utility of the analyte(s), and useful notes to help laboratorians easily reproduce the protocols discussed. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols, is a great resource for laboratorians who are already using mass spectrometry or thinking of introducing this technology to their laboratories.
Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols (Methods in Molecular Biology #2737)
by Uttam GargThis fully updated volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Exploring the versatility and flexibility of mass spectrometry, the book covers the advantages of this technology, which typically include elimination of the need for special reagents such as antibodies, increased sensitivity and specificity, and multi-component analysis enabling the screening of tens to hundreds of compounds in a single assay run. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols, Second Edition serves as a valuable resource for laboratory professionals who are already utilizing mass spectrometry or considering bringing this technology to their labs.
Clinical Applications of Mass Spectrometry: Methods and Protocols (Methods in Molecular Biology #603)
by Catherine A. Hammett-Stabler Uttam GargAs mass spectrometric methods now offer a level of specificity and sensitivity unrealized by spectrophotometric- and immunoassay-based methods, mass spectrometry has entered the clinical laboratory where it is being used for a wide range of applications. In Clinical Applications of Mass Spectrometry: Methods and Protocols, expert researchers provide detailed step-by-step procedures for the analysis of number of analytes of clinical importance. This versatile and expansive volume covers mass spectrometry methods for analytes including a variety of drugs, hormones, and metabolic compounds spanning the disciplines of toxicology, therapeutic drug monitoring, endocrinology, and pediatric metabolism. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include brief introductions to the analytes, lists of the necessary materials and reagents, readily reproducible analytical protocols, and detailed notes on troubleshooting and avoiding known pitfalls. Comprehensive and dependable, Clinical Applications of Mass Spectrometry: Methods and Protocols offers its readers a wide array of valuable methods for experienced mass spectrometric labs that are looking to introduce new analyses as well as for those laboratories currently considering the addition of this resourceful and vital technology.
Clinical Applications of Nucleic Acid Amplification (Methods in Molecular Biology #2621)
by Cynthia A. Schandl Meagan B. MyersThis volume details applications, methods, and protocols on nucleic acid amplification. Chapters detail the management of organ and stem cell transplantation, constitutional genetics and genomics, epidemiology, public health, nucleic acid detection, methods for amplification and sequencing, nuclease-assisted mutant allele enrichment, isothermal, and high-throughput sequencing. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Clinical Applications of Nucleic Acid Amplification is a valuable resource for both novice and expert scientists in this developing field.
Clinical Applications of PCR (Methods in Molecular Medicine #16)
by Y. M. LoAn unprecedented collection of core PCR techniques useful for the study and diagnosis of human diseases. Cutting-edge and essential for today's diagnostic laboratories, these techniques heavily utilize nonisotopic, solution phase, and in situ amplification methods. A significant number of chapters describe applications exploiting the exquisite sensitivity of PCR in the detection of rare or single cells, as in identifying fetal cells circulating in maternal blood, preimplantation embryo diagnosis, or detecting circulating cancer cells. The book demonstrates over and over again the power of PCR-its high sensitivity, specificity, and ability to rapidly discriminate sequence variations.
Clinical Applications of PCR, 2nd Edition (Methods in Molecular Biology #336)
by Y. M. LoIn this updated second edition of the much praised Clinical Applications of PCR, leading researchers apply molecular diagnostics to the many recent advances that have occurred in polymerase chain reaction (PCR)-based technologies. Highlights include real-time PCR, which allows the technique to be performed in a quantitative manner with improved sensitivity, robustness, and resilience to carryover contamination, mass spectrometric analysis of nucleic acids, and circulating cell-free nucleic acids in plasma. The authors apply these innovations to a broad spectrum of applications, including gene expression, methylation, trace molecule, gene dosage, and single cell analysis. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.<P><P> State-of-the-art and highly practical, Clinical Applications of PCR, Second Edition, will help today's laboratorians and researchers working in molecular diagnostics harness the power of these techniques with unprecedented sensitivity and ease.
Clinical Applications of PCR, Third Edition (Methods in Molecular Biology #1392)
by Rajyalakshmi Luthra Rajesh R. Singh Keyur P. PatelThis updated volume explores a wide variety of clinical applications of PCR such as detecting DNA methylation, detection of viruses and protozoa in infectious diseases, estimation of gene copy number aberrations, primer extension coupled with mass spectroscopy, and high throughput NGS techniques. The application of PCR has shown incredible value in the study of genomics and transcriptomics, not only for discovery but also for routine clinical applications, and it forms the cornerstone of personalized medicine. Written for the highly successful Methods in Molecular Biology series, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and authoritative, Clinical Applications of PCR, Third Edition serves as an ideal guide for researchers aiming to understand the principles behind each application and for their implementation in the laboratory.
Clinical Applications of Spectral Photon Counting Computed Tomography Technology
by Krzysztof Kris Iniewski Salim Aymeric Si-MohamedDive into the transformative world of Spectral Photon-Counting Computed Tomography (SPCCT), the groundbreaking technology revolutionizing diagnostic imaging. This book explores the latest advancements in SPCCT systems, revealing their unparalleled precision in detecting chronic, acute, and emergency conditions. Discover the cutting-edge technique of color K-edge imaging, which, combined with innovative contrast agents, may unveil unprecedented diagnostic clarity. From technical breakthroughs to emerging clinical applications, this comprehensive guide charts the future of radiology. A must-read for researchers, clinicians, and imaging enthusiasts eager to harness the potential of SPCCT to redefine medical diagnostics and improve patient outcomes.
Clinical Applications of the Polyvagal Theory: The Emergence Of Polyvagal-informed Therapies (Norton Series on Interpersonal Neurobiology #0)
by Stephen W. Porges Deb A. DanaInnovative clinicians share their experiences integrating Polyvagal Theory into their treatment models. Clinicians who have dedicated their work to bringing the benefits of the Polyvagal Theory to a range of clients have come together to present Polyvagal Theory in a creative and personal way. Chapters on a range of topics from compassionate medical care to optimized therapeutic relationships to clinician's experiences as parents extract from the theory the powerful influence and importance of cases and feelings of safety in the clinical setting. Additionally, there are chapters which: elaborate on the principle of safety in clinical practice with children with abuse histories explain the restorative consequences of movement, rhythm, and dance in promoting social connectedness and resilience in trauma survivors explains how Polyvagal Theory can be used to understand the neurophysiological processes in various therapies discuss dissociative processes and treatments designed to experience bodily feelings of safety and trust examine fear of flying and how using positive memories as an active "bottom up" neuroceptive process may effectively down-regulate defense shed light on the poorly understood experience of grief Through the insights of innovative and benevolent clinicians, whose treatment models are Polyvagal informed, this book provides an accessible way for clinicians to embrace this groundbreaking theory in their own work.
Clinical Aspects of Electroporation
by Stephen T. Kee Edward W. Lee Julie GehlElectroporation is the forefront in tumor ablation. This book presents the basic principles and clinical applications of electroporation, including the latest research results and patient data. A comprehensive approach to the basic science behind the development of this ground-breaking technique and its introduction into clinical practice, the book discusses the entire spectrum of currently available reversible treatments, the emerging irreversible applications, and their impact on patient care. Clinical Aspects of Electroporation is the first book intended for clinicians on this extremely important and rapidly developing field.
Clinical Aspects of Natural and Added Phosphorus in Foods (Nutrition and Health)
by Orlando M. Gutiérrez Kamyar Kalantar-Zadeh Rajnish MehrotraThis comprehensive reference covers the impact of dietary phosphorus in phosphorus physiology, public health and the pathogenesis of disease. Divided into three parts, the first section is an overview of the history of phosphorus and the regulation of phosphorus homeostasis. The second section focuses on specific matters related to phosphorus in the food supply. Clinical applications of the material presented in the preceding sections are pulled together in the third section - including the importance of both phosphorus excess and phosphorus deficiency for the pathogenesis of a wide variety of disease including kidney, cardiovascular, bone and oncologic diseases. Clinical Aspects of Natural and Added Phosphorus in Foods is an indispensable resource for understanding the growing importance of dietary phosphorus content in health and disease, enhancing patient care and moving forward the field of phosphorus science.
Clinical Atlas of 3D Printing Bone Reconstruction
by Hyun-Guy KangThis book provides practitioners with comprehensive guidance on the application of 3D printing technology in the bone reconstruction. The 3D printed implants need to be able to maximize function and minimize complications by reinforcing strength and changing shape beyond anatomically identical design. Many of the clinical cases in this book, including pre-operative images, surgical planning, design and fabrication, 3D printing implants and guides, surgery and postoperative images, will suffice to capture the sensation of the 3D printing bone reconstruction. This book is composed of photos with minimum descriptions so that the readers can develop their imaginative view.
Clinical Bioinformatics (Methods in Molecular Biology #1168)
by Ronald TrentIn Clinical Bioinformatics, Second Edition, leading experts in the field provide a series of articles focusing on software applications used to translate information into outcomes of clinical relevance. Recent developments in omics, such as increasingly sophisticated analytic platforms allowing changes in diagnostic strategies from the traditional focus on single or small number of analytes to what might be possible when large numbers or all analytes are measured, are now impacting patient care. Covering such topics as gene discovery, gene function (microarrays), DNA sequencing, online approaches and resources, and informatics in clinical practice, this volume concisely yet thoroughly explores this cutting-edge subject Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Clinical Bioinformatics, Second Edition serves as an ideal guide for scientists and health professionals working in genetics and genomics.
Clinical Bioinformatics (Methods in Molecular Medicine #141)
by Ronald J.A. TrentWith the ever-increasing volume of information in clinical medicine, researchers and health professionals need computer-based storage, processing and dissemination. In this book, leading experts in the field provide a series of articles focusing on software applications used to translate information into outcomes of clinical relevance. This book is the perfect guide for researchers and clinical scientists working in this emerging "omics" era.
Clinical Cardiac MRI (Medical Radiology)
by Andrew M. Taylor Vivek Muthurangu Jan Bogaert Steven DymarkowskiClinical Cardiac MRI is a comprehensive textbook intended for everyone involved in magnetic resonance imaging of the heart. It is designed both as a useful guide for newcomers to the field and as an aid for those who routinely perform such studies. The first edition, published in 2004-5, was very well received within the cardiac imaging community, and has generally been considered the reference because of its completeness, its clarity, and the number and quality of the illustrations. Moreover, the addition of a CD-ROM showing 50 real-life cases significantly enhanced the value of the book. In this second edition, the aim has been to maintain the same quality while incorporating the newest insights and developments in this rapidly evolving domain of medical imaging. The four editors, all experts in the field, have taken great care to ensure a homogeneous high standard throughout the book. Finally, the selection of 100 real-life cases, added as online material, will further enhance the value of this textbook.
Clinical Care of the Diabetic Foot 3rd Edition
by David G. Armstrong MPH Lawrence A. Lavery DpmThe third edition of Clinical Care of the Diabetic Foot has been fully revised and updated, and continues to be the essential handbook on foot care and the treatment of the diabetic foot. <P><P> The diabetic foot is typically the victim of nerve damage, micro- and macrovascular disease, and faulty healing, mechanisms that without proper care can lead to amputation. More than 80,000 diabetes-related amputations are performed in the United States each year, but non-specialist primary care providers, as well as residents, nurses, and diabetes educators, can help prevent this devastating, life-altering, and expensive complication. Healthcare professionals and medical students alike will find that this concise, well-indexed, and updated guide offers practical advice on detecting and managing diabetes-related foot complications.
Clinical Cases in Augmentative and Alternative Communication (Clinical Cases in Speech and Language Disorders)
by Martine M. SmithClinical Cases in Augmentative and Alternative Communication provides a concise introduction to the rapidly expanding field of augmentative and alternative communication (AAC). It brings together internationally renowned experts in the field to discuss its application and outline key principles of intervention to support communication using AAC. Carefully grounded in evidence-based clinical practice, the book highlights the diversity of potential applications for AAC across a wide range of client groups, including children and adults with developmental disabilities, as well as adults with acquired impairments. Most of the chapters are structured as case reports following CARE guidelines and highlight key principles for intervention that are grounded in clinical practice. The chapters also include reflections on communication through AAC and the valuable contributions that AAC can make in supporting independence and enhancing quality of life. This accessible book is ideal reading for students, novice clinicians in the fields of speech and language therapy or pathology, and professionals who are new to this area of clinical practice.
Clinical Cases in Dysphagia (Clinical Cases in Speech and Language Disorders)
by Margaret Walshe Maggie-Lee HuckabeeDysphagia is a complex condition that can have significant social, developmental and psychological effects. Alongside the physiology and pathophysiology of the condition, dysphagia can rob patients of the most basic pleasures, such as eating and drinking, causing ongoing difficulties for individuals in social situations throughout the lifespan. As an acknowledged component of evidence-based practice, the humble case report encourages clinical reflection and may be the spark that generates new thinking and motivation for future research. Clinical Cases in Dysphagia provides an opportunity to gain insight into the unique and varied presentation and management of dysphagia across a range of different conditions. With chapters provided by expert clinicians and based on clinical examples ‘from the trenches’, the reader may gain insights into their own practice patterns, refining their clinical problem solving and valuing the education that is offered to each of us by our patients. With additional online resources to support the case-based approach, the book emphasizes the importance of multidisciplinary care and reflects everyday clinical practice, making it a must-read for clinicians and students.