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Clinical Insights for Image-Guided Radiotherapy: Prostate (ISSN)
by Mike Kirby Kerrie-Anne CalderThis book provides a clinical insight into image-guided radiation therapy (IGRT) for prostate cancer. It starts by setting the clinical scene, discussing immobilisation and standard IGRT practice and then considering important developments like IGRT with non-ionising radiation, adaptive radiotherapy, particle therapy, margins, hypofractionation, clinical outcomes, AI and training. Good IGRT requires both technical and clinical focus. So, in complement to our first study guide on IGRT, this book now brings together key, clinical insights into IGRT for Prostate Cancer patients, with a view to helping the professional learn more about ‘how-to’ undertake IGRT for these patients more accurately, effectively and safely, throughout the whole course of a patient’s treatment with radiation.This clinical insight guide will be of interest to newly qualified radiation therapists, therapeutic radiographers, medical dosimetrists, medical physicists, radiotherapy physicists and clinical oncologists. It will also be of use for trainees and can be used alongside continuing competency and clinical training within real clinical departments and radiation therapy centres worldwide.This is the first in a forthcoming series of clinical insights, each tackling a different treatment area. Further areas in the series will be: Head and Neck; Thorax; Breast; Pelvis; and the Brain.Key Features:• Internationally applicable, clinically focused, up-to-date and evidence based.· Accompanied by suitable electronic multimedia resources.· Authored by experts with decades of experience of pioneering electronic portal imaging and IGRT in clinical practice, pedagogic research and substantial experience of teaching/supervising students, trainees and qualified therapists/medical physicists at bachelors, postgraduate and doctoral levels.Mike Kirby and Kerrie-Anne Calder are well-respected authors and radiotherapy professionals, who have worked in radiotherapy physics/radiotherapy clinical and academic practice for nearly 35 years and 25 years respectively.Mike Kirby is a Senior Lecturer in Radiotherapy Physics at the University of Liverpool, UK, and an Honorary Lecturer at the University of Manchester, UK. He holds graduate and postgraduate qualifications in medical physics and has in total over 200 books, papers, oral and poster presentations to his name in the field of radiotherapy. Dr. Kirby holds professional membership of the Institute of Physics and Engineering in Medicine, the American Association of Physicists in Medicine, the American Society for Radiation Oncology, the European Society for Radiotherapy and Oncology and the British Institute of Radiology, is a Fellow of the Higher Education Academy and the British Institute of Radiology in the UK.Kerrie-Anne Calder is a Lecturer at the University of Liverpool, UK, where she educates undergraduate and post graduate students in many aspects of radiotherapy with a special interest and role in imaging training. Kerrie-Anne has graduate and postgraduate qualifications in radiotherapy, education and academic practice, is a member of the Society and College of Radiographers, and is a Fellow of the Higher Education Academy in the UK. She was a clinical and professional lead in IGRT (on-treatment verification imaging) within the NHS in the UK for over ten years.
Clinical Integration of Neuropsychological Test Results
by Charles J. Golden Ryan BennettThe interpretation of neuropsychological tests is a complex process which requires recognition of the multiple skills required to complete even the simplest tests. The purpose of this volume is to explore the various interpretive strategies used with a wide variety of commonly used tests in order to see beyond the skills suggested by the test title. By integrating these possible interpretations across multiple tests, the neuropsychologist can pinpoint those deficits which lie at the core of a client’s pattern of test results. It is intended for both professionals and for students starting to learn the clinical practice of neuropsychology.
Clinical Investigation (Advances in Experimental Medicine and Biology #1047)
by Mieczyslaw PokorskiClinical investigation plays an essential role in the differential diagnosis, biomarker development, and therapy and cure of diseases. The book presents a bench-to-bed approach, with broad empirical coverage by experienced practitioners. The articles include topics like cytokine receptors in lung cancer, conduciveness of oxidative stress to carcinogenesis, safety and effectiveness of surgical correction of deformed chest, diagnostic and treatment regimens in inflammation-ridden obstructive lung conditions, alterations in growth hormone secretion leading to disorders of growth and metabolism, microbiota transplantation in pediatric patients, and the promising markers of renal epithelial injury. Yet another issue concerns the restructuring of chronic pain management by establishing the community-based specialized pain clinics. The book aims to disseminate and deliberate on the latest interdisciplinary medical knowledge to enhance clinical outcomes. Being a blend of clinical investigation and practice the book is addressed to physicians, scientists, and allied health care professionals.
Clinical Investigation of Portal Hypertension
by Katsutoshi ObaraThis book thoroughly covers various diseases induced by portal hypertension, and introduces novel information for the treatment of patients. Individual chapters address the pathophysiology, diagnosis and treatment options available for the complications induced by portal hypertension. The book fosters practical understanding and provides more evidence-based treatment options in order to improve physicians’ ability to select optimal treatment methods for their patients. Further, it offers readers the latest information concerning developments of the disease such as esophaogastric varices, ectopic varices, portal thrombosis, refractory ascites and hepatic encephalopathy. Clinical Science of Portal Hypertensions is an indispensible resource for both beginning and experienced gastroenterological physicians, endoscopists, liver physicians, radiologists, gastroenterological surgeons, liver surgeons, etc. who treat patients with portal hypertension on a clinical or research basis.
Clinical Investigations on the Move
by Andrew Walker Rory Mackinnon Lina FazlanieThe Medicine on the Move series provides fully flexible access to subjects across the curriculum in a unique combination of print and mobile formats ideal for the busy medical student and junior doctor. No matter what your learning style, whether you are studying a subject for the first time or revisiting it during exam preparation, Medicine on the
Clinical Kinesiology and Anatomy (Fifth Edition)
by Lynn S. LippertThis book provides fundamental understanding of Kinesiology and anatomy from a clinical perspective.The anatomical basis of common pathological conditions is briefly described in most chapters to give greater clinical relevance.
Clinical Kinesiology and Biomechanics: A Problem-Based Learning Approach
by Gordon J. Alderink Blake M. AshbyThis new textbook uses a problem-based learning (PBL) approach for teaching the fundamentals of kinesiology and biomechanics to undergraduate and graduate students in the biomedical, rehabilitative, and exercise science fields. Case vignettes and problems for each major region of the body are presented – cervical spine, thoracic spine and rib cage, lumbar spine and pelvis, shoulder girdle, elbow/forearm, wrist, hand, hip, knee, and ankle/foot. For the cases on the spine and upper extremity, biomechanics of posture are included; for cases involving the hip, knee, and ankle/foot, an extensive study of gait analysis is also incorporated. These case vignettes are not preceded by chapters that provide foundational information. Rather, relevant anatomical, biomechanical, and other information needed to solve/explain each case are embedded in the relevant chapters presenting the clinical cases.
Clinical Laboratory Chemistry
by Robert SunheimerClinical Laboratory Chemistry is a part of Pearson’s Clinical Laboratory Science series of textbooks, which is designed to balance theory and application in an engaging and useful way. Highly readable, the book concentrates on clinically significant analyses students are likely to encounter in the lab. The combination of detailed technical information and real-life case studies helps learners envision themselves as members of the health care team, providing the laboratory services specific to chemistry that assist in patient care. The book’s fundamental approach and special features allow students to analyze and synthesize information, and better understand the ever-evolving nature of clinical chemistry. The Second Edition has been streamlined and updated to include four new chapters covering safety, pediatrics, geriatrics, and nutrition; real-life mini cases; new figures and photographs; updated sources and citations; and a complete teaching and learning package.
Clinical Laboratory Hematology (Second Edition)
by Shirlyn B. MckenzieDesigned to meet the needs of both clinical laboratory technicians and clinical laboratory scientists, CLINICAL LABORATORY HEMATOLOGY has been updated into a brand new edition. This comprehensive--yet easy to read--guide to hematology and hemostasis features cutting-edge technologies, high-quality photographs and micrographs, case studies, and convenient dual-level (basic and advanced) presentation of information. Visual cross-referencing (symbols) throughout make finding information exceptionally easy. Key chapters are presented by a number of different authors and experts in the field and include information on: cellular homeostasis; the Stucture and Function of Hematopoietic Organs; Hemolytic anemia; Nonmalignant lymphocyte disorders and much more.
Clinical Laboratory Management
by Shakti Kumar Yadav Sompal Singh Ruchika GuptaMedical laboratories not only assist the physicians in diagnosis and management of a disease but also play a role in community health. Apart from the analytical aspects of various investigations, the larger areas of human resource management, inventory management and the like have been gaining importance as a part of laboratory management. There is a felt need for an understanding of the managerial aspects of a clinical laboratory, especially in an institutional setting. Although this knowledge can be acquired from books on general management subject, there is a paucity of books dedicated to clinical laboratory management. Hence is a need for a simple and concise text for management in the clinical laboratory practice. This first-of-its-kind book contains 50 chapters and is divided into ten sections. It is intended to provide an all-encompassing overview of management in a clinical laboratory and is written in a way that makes the content easy-to-comprehend, especiallyfor those who have not been trained in the core management concepts. The book begins with an introduction to Laboratory Management and makes the reader familiar with the general aspect of management. Each section that follows focuses on an important aspect of laboratory management, including but not limited to human resource management, accounting and finance, quality control, laboratory hazards and safety, and more. Clinical Laboratory Management shall be a valuable resource for clinical laboratorians, students of medical laboratory technology, laboratory managers, and hospital managers. It aims to help readers understand the managerial aspects of a clinical laboratory and serve as more efficient clinical laboratory managers.
Clinical Laboratory Management (ASM Books)
by Lynne Shore GarciaClinical Laboratory Management Apply the principles of management in a clinical setting with this vital guide Clinical Laboratory Management, Third Edition, edited by an esteemed team of professionals under the guidance of editor-in-chief Lynne S. Garcia, is a comprehensive and essential reference for managing the complexities of the modern clinical laboratory. This newly updated and reorganized edition addresses the fast-changing landscape of laboratory management, presenting both foundational insights and innovative strategies. Topics covered include: an introduction to the basics of clinical laboratory management, the regulatory landscape, and evolving practices in the modern healthcare environment the essence of managerial leadership, with insights into employee needs and motivation, effective communication, and personnel management, including the lack of qualified position applicants, burnout, and more financial management, budgeting, and strategic planning, including outreach up-to-date resources for laboratory coding, reimbursement, and compliance, reflecting current requirements, standards, and challenges benchmarking methods to define and measure success the importance of test utilization and clinical relevance future trends in pathology and laboratory science, including developments in test systems, human resources and workforce development, and future directions in laboratory instrumentation and information technology an entirely new section devoted to pandemic planning, collaboration, and response, lessons learned from COVID-19, and a look towards the future of laboratory preparedness This indispensable edition of Clinical Laboratory Management not only meets the needs of today’s clinical laboratories but anticipates the future, making it a must-have resource for laboratory professionals, managers, and students. Get your copy today, and equip yourself with the tools, strategies, and insights to excel in the complex and ever-changing world of the clinical laboratory.
Clinical Low Field Strength Magnetic Resonance Imaging: A Practical Guide to Accessible MRI
by Hans-Martin KleinThis book covers all aspects of low field MRI, describing its advantages, problems and prerequisites. Individual chapters are devoted to site planning, safety considerations, coils, imaging technique, image quality optimization, the imaging of different anatomic regions and likely future developments. The factors that must be borne in mind when selecting a low field system are clearly identified and detailed attention is paid to the applications for which such a system is adequate. The focus on high field systems has led to a situation where only a few systems with field strengths lower than 0. 5 T survive. Some of these systems possess high field features such as multichannel coils and strong gradients; furthermore, sequence technology and image processing techniques taken from higher field strength systems have resulted in impressive imaging capabilities. While 1. 5-T systems will probably continue to remain the standard, low field systems offer advantages such as the feasibility of dynamic joint examinations, improvement of T1 contrast, reduction of "missile effects" and decreased radiofrequency exposure. Low field strength MRI consequently has the potential to contribute to optimal patient management and given comparable image quality, its application may become an issue of patient safety. This book will be an invaluable asset to all who are involved in planning and/or running a low field strength MRI facility.
Clinical MR Neuroimaging
by Peter B. Barker Jonathan H. Gillard Adam D. Waldman Jonathan H. Gillard Adam D. WaldmanThe physiological magnetic resonance techniques of diffusion imaging, perfusion imaging and spectroscopy offer insights into brain structure, function and metabolism. Until recently, they were mainly applied within the realm of medical research, but with their increasing availability on clinical MRI machines, they are now coming into clinical practice for the evaluation of neuropathology in individual patients. This book provides the reader with a thorough review of the underlying physical principles of each of these methods, as well as comprehensive coverage of their clinical applications. Topics covered include single- and multiple-voxel MRS techniques, MR perfusion based on both arterial spin labelling and dynamic bolus tracking approaches, and diffusion-weighted imaging, including techniques for mapping brain white matter fiber bundles. Clinical applications are reviewed in depth for each technique, with case reports included throughout the book. Attention is also drawn to possible artifacts and pitfalls associated with these techniques.
Clinical MR Spectroscopy
by Peter B. Barker Alberto Bizzi Nicola De Stefano Rao P. Gullapalli Doris D. M. LinIn vivo magnetic resonance spectrosopy (MRS) is increasingly being used in clinical practice, particularly for neurological disorders.
Clinical MRI of the Abdomen: Why,How,When
by Nicholas C. GourtsoyiannisThis volume, which explains why, when, and how abdominal MRI should be used, focuses in particular on the most recent developments in the field. After introductory chapters on technical considerations, protocol optimization, and contrast agents, MRI of the various solid and hollow viscera of the abdomen is addressed in a series of detailed chapters. Relevant clinical information is provided, and state of the art protocols presented. With the help of numerous high-quality illustrations, normal, variant, and abnormal imaging findings are described and potential artefacts highlighted. Differential diagnosis is given extensive consideration, and comparisons are made with competing methodologies when relevant. Each of the chapters is rounded off by a section on "pearls and pitfalls". The closing chapters focus on findings in the pediatric abdomen, advances in MRI specifically relevant to cancer patients, and the use of abdominal MRI at 3 Tesla. This book, written by leading experts, will be of value to all who are involved in learning, performing, interpreting, and reporting abdominal MRI examinations.
Clinical Management of Challenges in Allogeneic Stem Cell Transplant (Advances in Experimental Medicine and Biology #1475)
by Karen BallenThe purpose of the book is to focus attention and offer suggestions on controversial and challenging topics in allogeneic stem cell transplant. Over 40,000 allogeneic hematopoietic cell transplants (HCT) are done worldwide each year. Despite advances in allogeneic transplant, the cure rate is only 50-70%, depending on disease and patient factors. The book focuses on key topics such as patient selection, donor selection, conditioning regimens, graft vs. host disease prophylaxis regimens, maintenance strategies, and other topics that affect patient outcomes. The authors also discuss access to transplant care. Through dissemination of these topics, we hope to educate health care professionals caring for these patients, and improve patient outcomes. This is an essential resource for transplant physicians, hematologists/oncologists, and advance practice providers. Several of the topics are controversial issues that are discussed “round the table” frequently by transplant teams.
Clinical Management of Pulmonary Disorders and Diseases (Advances in Experimental Medicine and Biology #1022)
by Mieczyslaw PokorskiThe book endeavors to provide a stimulating and thought provoking scientific content to share and exchange new clinical studies and advancements in dealing with pulmonary diseases. The topics vary from clinical to translational research in respiratory diseases such as lung cancer, obstructive sleep apnea, chronic obstructive pulmonary disease, bacterial and fungal infections, lung lesions during febrile maladies, and others. An attempt has been made to show the intertwined relationship between the pulmonary system and other body systems such as kidney, cardiac, or hormonal functions. The ensuing interlocked morbidities, often exacerbating one another, require the coordination of various medical specialties to optimize the diagnostic and therapeutic processes. The knowledge sharing through publications of research and clinical experiences is indispensable to accelerate the innovation spectrum and to continue working on the therapeutic and preventive strategies in chronic pulmonary diseases. The book is addressed to pulmonologists, chest physicians, researchers, and healthcare professionals engaged in patient care.
Clinical Manual of Small Animal Endosurgery
by Alasdair Hotston Moore Rosa Angela RagniA practical and comprehensive guide to rigid endoscopy and endosurgery in small animal practice. Fully illustrated throughout, it covers the clinical treatment of small animals from pre-operative through to post-operative care. With reference to specific procedures, this manual includes guidance on the selection of equipment, surgical techniques, anaesthesia and possible complications. A specialist chapter advising on the treatment of birds, reptiles and small mammals is also included.Clinical Manual of Small Animal Endosurgery will enable veterinarians to develop and improve their endoscopic techniques in clinical practice, as well as providing guidance on referral options for more complex cases.KEY FEATURES* Provides comprehensive information on how to perform rigid endoscopic investigations and procedures.* The focus is on dogs and cats with a specialist chapter covering the treatment of exotic small animals* Contains many full colour clinical photographs* Written and edited by experts in the field
Clinical Medicine Research (Advances in Experimental Medicine and Biology #1116)
by Mieczyslaw PokorskiThis book presents an update on new trends and developments in broadly defined medical disciplines. The whole range of multidisciplinary topics are tackled, regarded as being important for advancing the understanding of disease pathogenicity, diagnostic methods, and patient management. The topics include a holistic approach to physiotherapy, with proprioceptive neuromuscular facilitation at the core of it, potential ways to protect kidneys during ischemic coronary interventions, and psychosocial aspects in cancer survivors. Other topics deal with growth hormone deficiency in short children and responses of molecular markers of bone metabolism to growth hormone replacement therapy and with the modern use of transcranial laser-induced photobiomodulation showing surprising benefits in autism disorder. The expert contributions take on the challenges presented to medical professionals by ever growing medical knowledge and various individual and contextual issues that require a multidisciplinary approach in patient management. The authors present a bench-to-bed clinical research to make useful additions to the knowledge on contemporary diagnostic procedures, therapy, and quality of life of patients. The book aims to provide stimulus for new research ideas and to give new perspectives on practical clinical issues. The book is intended for primary care clinicians, family physicians, medical scholars, and other clinicians who treat and manage patients.
Clinical Mentation Evaluation: A Connectomal Approach to Rapid and Comprehensive Assessment
by Michael HoffmannThis first-of-its-kind book offers clinicians a unique and comprehensive system of cognitive and behavioral testing that is tiered and context-appropriate for the diagnosis of mental status. Because the challenge nowadays with neurologic syndrome presentations is no longer merely lesion localization, but the degree, extent and nature of a cognitive and/or behavioral impairment, this work proposes a more targeted system of mentation evaluation -- one that incorporates behavioral, neurological, neuropsychiatric, and neuropsychological components. Developed by synthesizing outcomes data from a range of stroke registries, this novel work offers a stepwise, hierarchical approach to mentation evaluation largely determined by level of consciousness and degree of cooperation. Organized across 14 chapters, the book begins with an introduction to the challenges of cognitive and behavioral assessment, as well as a discussion of various clinical presentations ranging from mild behavioral impairment to cognitive reserve and its implications. Subsequent chapters then address various approaches to mental status evaluation and explore how these tests affect brain physiology. The work closes with a unique discussion of the various lay populations that may benefit from cognitive and behavioral evaluation. Authored by a renowned expert in the field, Clinical Mentation Evaluation: A Connectomal Approach to Rapid and Comprehensive Assessment is an invaluable reference that seeks to revitalize neurological and psychiatric disease measurement within the clinical setting. The work will be of interest to all clinicians in training and clinical practice who regularly, or even periodically, conduct mental status examination.
Clinical Metabolomics Applications in Genetic Diseases
by Anas M. Abdel RahmanThis book helps readers discover the forefront of personalized medicine on clinical metabolomics and its applications in genetic diseases. This comprehensive guide offers a functional relationship map between cell components and genetic variations in various diseases, providing insights that can be applied to personalized medicine. The book covers the latest developments in metabolomics for health, with practical guidance for clinical experts looking to advance their laboratory techniques and career. The metabolomics profile is a powerful tool that has revolutionized our understanding of the relationship between genetics, clinical readouts, and disease outcomes. By integrating metabolomics with genomics and clinical phenotypes, the authors have developed diagnostic and prediction models that have vastly improved patient outcomes and deepened the understanding of disease mechanisms. This model has been successfully applied in various conditions, including inborn errors of metabolism, primary immunodeficiency, and endocrine disorders. However, integrating metabolomics with other omics datasets and clinical phenotypes requires careful study design, analytical tools, and data analysis and interpretation. This groundbreaking new book provides essential guidance for researchers, students, and professionals looking to leverage metabolomics in their own work, including biochemical and clinical geneticists, pharmacogenomics and pharmacometabolomics experts, pharmaceutics and diagnostic researchers, medical scientists, clinical dietitians, metabolic engineers, clinical chemists, and personalized medicine specialists.
Clinical Metabolomics: Methods and Protocols (Methods in Molecular Biology #1730)
by Martin GieraThis detailed volume presents a comprehensive compendium of clinical metabolomics protocols covering LC-MS, GC-MS, CE-MS, and NMR-based clinical metabolomics as well as bioinformatics and study design considerations. The methodologies explored here form the core of several very promising initiatives evolving around personalized health care and precision medicine, which can be seen as complimentary to the field of clinical chemistry and aid the aforementioned field with novel disease markers and diagnostic patterns. Written for the highly successful Methods in Molecular Biology series, chapters include brief introductions to their topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Clinical Metabolomics: Methods and Protocols aims to serve as the basis for successful communication between scientists from several fields, including chemists, biologist, bioinformaticians, and clinicians, ultimately leading to effective study design and completion.
Clinical Metabolomics: Methods and Protocols (Methods in Molecular Biology #2855)
by Martin Giera Elena Sánchez-LópezThis second edition volume presents new and updated protocols on comprehensive compendium of clinical metabolomics protocols covering LC-MS, GC-MS, CE-MS, and NMR-based clinical metabolomics as well as bioinformatics and study design considerations. Chapters explore the core of several promising initiatives evolving around personalized health care and precision medicine. Written for the highly successful Methods in Molecular Biology series, chapters include brief introductions to their topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Clinical Metabolomics: Methods and Protocols, Second Edition aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
Clinical Microbiology Made Ridiculously Simple
by Mark Gladwin William Trattler C. Scott MahanA brief, clear, thorough, and highly enjoyable approach to clinical microbiology, brimming with mnemonics, humor, summary charts and illustrations, from AIDS to flesh-eating bacteria to ebola, mad cow disease, hantavirus, anthrax, smallpox, botulism, etc. Significant updates. Excellent Board review.
Clinical Microbiology Made Ridiculously Simple
by William Trattler C. Scott Mahan Mark R. GladwinThis book attempts to facilitate the learning of microbiology by presenting the information in a clear and entertaining manner brimming with memory aids. The text has been updated to include current information on rapidly developing topics, such as HIV and AIDS (vaccine efforts and all the new anti-HIV medications), Avian Influenza H5N1, SARS Coronavirus, Ebola virus, Hantavirus, E. coli outbreaks, Mad Cow Disease, brand-new antimicrobial antibiotics, and agents of bioterrorism. <p><p>The mnemonics and cartoons in this book do not intend disrespect for any particular patient population or racial or ethnic group but are solely presented as memory devices to assist in the learning of a complex and important medical subject.