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CPO Focus on Physical Science
by Thomas C. HsuMiddle school science textbook, with many experiments and activities.
CPP, Cell-Penetrating Peptides
by Ülo LangelIn this book, a summary and update of the most important areas of CPP research are presented, whilst raising relevant questions for further development. The CPP sequences are presented and discussed throughout the book. The methods for testing CPP mechanisms are discussed in detail. Various approaches for the testing of endocytotic pathways of CPP uptake are also described. Different CPP uptake experiments are compared since it is becoming clear that it is often best to apply several methods in a complementary manner in order to most comprehensively evaluate CPP uptake mechanisms due to the complexity of these processes. A brief summary of functionality issues of CPPs, both in vitro and in vivo are discussed. Therapeutic potential of CPPs and commercial developments are discussed. The monograph is written for researchers and students in the field.
CPP, Cell-Penetrating Peptides
by Ülo LangelIn this book, a summary and update of the most important areas of cell-penetrating peptides (CPP) research are presented, while raising relevant questions for further development. The CPP sequences are presented and discussed throughout the book. The methods for testing CPP mechanisms are discussed in detail. Various approaches for the testing of endocytotic pathways of CPP uptake are also described. Different CPP uptake experiments are compared since it is becoming clear that it is often best to apply several methods in a complementary manner in order to most comprehensively evaluate CPP uptake mechanisms due to the complexity of these processes. A brief summary of functionality issues of CPPs, both in vitro and in vivo, is discussed. Therapeutic potential of CPPs and commercial developments are discussed. The present, second edition of this book is the updated and expanded version of the first edition, published in 2019. The development of the field of cell-penetrating peptides in these five years has been obvious and exciting. This second edition of the book has been partly reorganized and comprehensively expanded with the exciting research in 2019-2023. Around 2500 novel scientific articles have become available, most of them are reviewed in the second edition. Additional rapidly growing areas of high impact presented in this second edition are therapeutic developments (Chapter 16) and delivery of oligonucleotides and proteins/peptides (Chapters 5 and 6) including novel reports on genome editing with CPP assistance. Also, several additional examples are available now on clinical trials using CPPs (Chapter 15). The book is written for researchers and students in the field.
The Crab Alphabet Book
by Jerry PallottaWith his signature humor and amazing facts, best-selling author Jerry Pallotta offers a decapod for every letter of the alphabet.Meet dozens of crustaceans--and a few bonus animals--with engaging text and a laugh-out-loud narrative, from A (Arrow Crab) to E (exoskeleton) to I (Imocaris, a kind of fossil scientists believe to be the first crab on earth) to Z (Zebra Hermit Crabs, which have a hard covering on their legs and claws, but their body is soft). Readers of all ages will be entertained (and learning!) with every page turn.
Crabs: A Global Natural History
by Peter J. DavieA richly illustrated natural history of the world's crabs that examines their diversity, ecology, anatomy, behavior, and moreThis lavishly illustrated book offers a remarkable look at the world’s crabs. More than 7,000 crab species, in 100 different families, are known today. Their unique physiology and complex behaviors have made them one of the most diverse and adaptable of all animal groups. They can thrive in the darkness of abyssal seas, on the edges of scalding hot volcanic hydrothermal vents, on sunlit coral reefs, on wave-washed rocky shores, and in tropical rain forests at the tops of mountains. They even persist in some of the harshest desert conditions. Playing a vital role in marine and coastal ecology, crabs have been identified as keystone species in habitats such as coral reefs and coastal tropical swamps.Crabs comprises five chapters: evolutionary pathways; anatomy and physiology; ecology; reproduction, cognition, and behavior; and exploitation and conservation. Individual chapters include a variety of subtopics, each illustrated by exceptional images, and followed by numerous double full-page species’ profiles. Each profile has been chosen to emphasize remarkable and intriguing aspects of the life of these fascinating creatures. Some species may be familiar, but many are beyond anything you have probably seen before and will stretch your understanding of what a crab is.Written by a world authority, Crabs offers an accessible overview of these fascinating crustaceans.More than 190 spectacular color photographsAccessible and well-organized chaptersFull profiles on 42 iconic species from across the world
Crabs, Dabs and Rock Pools (Early Reader Non Fiction)
by Tony De SaullesDiscover the wonderful world of beach creatures with this brand new green Early Reader factbook from Horrible Sciences illustrator, Tony De Saulles.Early Readers are stepping stones from picture books to reading books. A green Early Reader is a first factbook.It's never too early to find out about . . . Rockpools, crabs, shells and seaweed!Did you know that crabs can grow new shells as they get bigger? Or that starfish have lots of tiny feet for moving around underwater?A fact-filled guide to everything you could ever want to find at the beach, with full colour illustrations on every page.
Crabs (Nature's Children)
by Jen GreenHow many different kinds of crabs are there? What do crabs eat? Do all crabs live in the ocean? How big are giant spider crabs? Find the answers to these questions, and learn much more about the physical characteristics, behavior, habitat, and lives of crabs.
The CRAC Channel: Methods and Protocols (Methods in Molecular Biology #1843)
by Aubin Penna Bruno ConstantinThis volume discusses the cellular and molecular techniques used to study and characterize the different components of the CRAC channel signaling pathway. The chapters in this book cover topics such as fluorescence-based measurements of the CRAC channel activity in cell populations; patch-clamp recording of the CRAC channel in STIM-Orai overexpressing cells and native systems; western-blotting and co-immunoprecipitation of endogenous STIM/ORAI and protein partners; shRNA-mediated gene silencing; and the SC-SMD system. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Thorough and cutting-edge, The CRAC Channel: Methods and Protocols is a valuable resource for any researcher interested in learning more about the CRAC channel, as its activation mechanism and roles in cellular functions have yet to be completely explored.
A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution
by Jennifer A. Doudna Samuel H. SternbergA trailblazing biologist grapples with her role in the biggest scientific discovery of our era: a cheap, easy way of rewriting genetic code, with nearly limitless promise and peril. Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR—a revolutionary new technology that she helped create—to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers, and will help address the world’s hunger crisis. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences—to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create “better” humans. Writing with fellow researcher Samuel Sternberg, Doudna shares the thrilling story of her discovery, and passionately argues that enormous responsibility comes with the ability to rewrite the code of life. With CRISPR, she shows, we have effectively taken control of evolution. What will we do with this unfathomable power?
The Crack in the Cosmic Egg: New Constructs of Mind and Reality
by Joseph Chilton Pearce Thom HartmannThe classic work that shaped the thought of a generation with its powerful insights into the true nature of mind and reality. • Defines culture as a "cosmic egg" structured by the mind's drive for logical ordering of its universe. • Provides techniques allowing individuals to break through the vicious circle of logic-based systems to attain expanded ways of creative living and learning. The sum total of our notions of what the world is--and what we perceive its full potential to be--form a shell of rational thought in which we reside. This logical universe creates a vicious circle of reasoning that robs our minds of power and prevents us from reaching our true potential. To step beyond that circle requires a centering and focus that today's society assaults on every level. Through the insights of Teilhard, Tillich, Jung, Jesus, Carlos Castaneda, and others, Joseph Chilton Pearce provides a mode of thinking through which imagination can escape the mundane shell of current construct reality and leap into a new phase of human evolution. This enormously popular New Age classic is finally available again to challenge the assumptions of a new generation of readers and help them develop their potential through new creative modes of thinking. With a masterful synthesis of recent discoveries in physics, biology, and psychology, Pearce reveals the extraordinary relationship of mind and reality and nature's blueprint for a self-transcending humanity.
Cracked: Life on the Edge in a Rehab Clinic, A Doctor's Story
by Drew Pinsky Todd GoldDr. Drew Pinsky is best known as the cohost of the long-running radio advice program Loveline. But his workday is spent at a major Southern California clinic, treating the severest cases of drug dependency and psychiatric breakdown. In this riveting book, Pinsky reveals the intimate and often shocking stories of his patients as they struggle with emotional trauma, sexual abuse, and a host of chemical nemeses: alcohol, marijuana, Ecstasy, heroin, speed, cocaine, and prescription drugs. At the center of these stories is Pinsky himself, who immerses himself passionately, almost obsessively, in his work. From the sexually compulsive model to the BMW-driving soccer mom, Cracked exposes, in fast-moving, powerful vignettes, the true scope and severity of addiction, a nationwide epidemic.
Cracked Coverage: Television News, The Anti-Cocaine Crusade, and the Reagan Legacy
by Jimmie L. Reeves Richard CampbellCarefully documenting the deceptions and excesses of television news coverage of the so-called cocaine epidemic, Cracked Coverage stands as a bold indictment of the backlash politics of the Reagan coalition and its implicit racism, the mercenary outlook of the drug control establishment, and the enterprising reporting of crusading journalism. Blending theoretical and empirical analyses, Jimmie L. Reeves and Richard Campbell explore how TV news not only interprets "reality" in ways that reflect prevailing ideologies, but is in many respects responsible for constructing that reality. Their examination of the complexity of television and its role in American social, cultural, and political conflict is focused specifically on the ways in which American television during the Reagan years helped stage and legitimate the "war on drugs," one of the great moral panics of the postwar era.The authors persuasively argue, for example, that powder cocaine in the early Reagan years was understood and treated very differently on television and by the state than was crack cocaine, which was discovered by the news media in late 1985. In their critical analysis of 270 news stories broadcast between 1981 and 1988, Reeves and Campbell demonstrate a disturbing disparity between the earlier presentation of the middle- and upper-class "white" drug offender, for whom therapeutic recovery was an available option, and the subsequent news treatment of the inner-city "black" drug delinquent, often described as beyond rehabilitation and subject only to intensified strategies of law and order. Enlivened by provocative discussions of Nancy Reagan's antidrug activism, the dramatic death of basketball star Len Bias, and the myth of the crack baby, the book argues that Reagan's war on drugs was at heart a political spectacle that advanced the reactionary agenda of the New and Religious Right--an agenda that dismissed social problems grounded in economic devastation as individual moral problems that could simply be remedied by just saying "no."Wide ranging and authoritative, Cracked Coverage: Television News, the Anti-Cocaine Crusade, and the Reagan Legacy is a truly interdisciplinary work that will attract readers across the humanities and social sciences in addition to students, scholars, journalists, and policy makers interested in the media and drug-related issues.
Cracked Open: Liberty, Fertility and the Pursuit of High Tech Babies
by Miriam Zoll Judy Norsigian Michele GoodwinCracked Open is Miriam Zoll's eye-opening account of growing into womanhood with the simultaneous opportunities offered by the U. S. women's movement and new discoveries in reproductive technologies. Influenced by the pervasive media and cultural messages suggesting that science had finally eclipsed Mother Nature, Zoll postponed motherhood until the age of 40. When things didn't progress as she had hoped, she enters a world of medical seduction and bioethical quagmires. Desperate to conceive, she surrenders to unproven treatments and procedures only to learn that the odds of becoming a mother through reproductive technologies are far less than she and her generation had been led to believe.
Cracking Anatomy (Cracking Series)
by Ken Okona-MensahFrom your dividing cells to your beating heart, this book takes a comprehensive look at the human body and reveals the extraordinary way your anatomy and physiology intertwine.In 13 illustrated chapters, Cracking Anatomy makes sense of all the body's systems, explains medical terminology and explores questions including:· How does your brain really see you?· How does age affect your muscles and bones? · How and why cells die?· Why the shape of a criminal's hands could be used to help identify them?· Can you exercise too much? · Which of the five senses is most important?· What triggers puberty?· Why your immune system has more than one line of defence?· Why anatomical quirks are more important than you think?· How long does it take for your body to digest food? · How many times does your heart beat in a day?· Why do we sleep?An accessible, comprehensive and fully illustrated guide to this absorbing area, Cracking Anatomy will both educate and excite all readers.
Cracking Anatomy
by Ken Okona-MensahFrom your dividing cells to your beating heart, this book takes a comprehensive look at the human body and reveals the extraordinary way your anatomy and physiology intertwine.In 13 illustrated chapters, Cracking Anatomy makes sense of all the body's systems, explains medical terminology and explores questions including:· How does your brain really see you?· How does age affect your muscles and bones? · How and why cells die?· Why the shape of a criminal's hands could be used to help identify them?· Can you exercise too much? · Which of the five senses is most important?· What triggers puberty?· Why your immune system has more than one line of defence?· Why anatomical quirks are more important than you think?· How long does it take for your body to digest food? · How many times does your heart beat in a day?· Why do we sleep?An accessible, comprehensive and fully illustrated guide to this absorbing area, Cracking Anatomy will both educate and excite all readers.
Cracking Key Concepts in Secondary Science (Corwin Ltd)
by Adam Boxer Heena Dave Gethyn JonesThe perfect companion to help you crack some of secondary science’s most challenging concepts in your teaching. Secondary science teaching is a heroic task, taking some of humanity’s greatest discoveries and explaining them to the next generation of students. Cracking some of the trickiest concepts in biology, chemistry and physics, with walkthrough explanations and examples inspired by direct instruction, this book will bring a fresh perspective to your teaching. · 30 key concepts explored in depth · Understand what students should know before and after the lesson · Tips and tricks offer detailed advice on each topic · Checks for understanding so you can test your students’ knowledge Adam Boxer is Head of Science at The Totteridge Academy in North London. Heena Dave was Head of Science at Bedford Free School. Gethyn Jones is a teacher of physics at an independent school in London
Cracking Key Concepts in Secondary Science (Corwin Ltd)
by Adam Boxer Heena Dave Gethyn JonesThe perfect companion to help you crack some of secondary science’s most challenging concepts in your teaching. Secondary science teaching is a heroic task, taking some of humanity’s greatest discoveries and explaining them to the next generation of students. Cracking some of the trickiest concepts in biology, chemistry and physics, with walkthrough explanations and examples inspired by direct instruction, this book will bring a fresh perspective to your teaching. · 30 key concepts explored in depth · Understand what students should know before and after the lesson · Tips and tricks offer detailed advice on each topic · Checks for understanding so you can test your students’ knowledge Adam Boxer is Head of Science at The Totteridge Academy in North London. Heena Dave was Head of Science at Bedford Free School. Gethyn Jones is a teacher of physics at an independent school in London
Cracking Neuroscience (Cracking Series)
by Jon TurneyFor so long, the brain was the great unknown of human biology; an evolved complex of cells, chemicals and electricity, which eluded even the understanding of its own grey matter. Now, in this comprehensive guide, the most complicated concepts from across the field of neuroscience - such as memory, addiction and mind mapping - are broken down into easily understandable bite-sized pieces, to give everyone the chance to understand their own brain. Includes sections on:-The anatomy of the brain-Neurons, synapses and axons - the building blocks of the brain-Differences in male and female development-Modern treatment of mental illness-The effects on the brain of different food and stimulants-Memory, senses, cravings-Fight or flight-Perception and sensation-The future of neuroscience
Cracking Neuroscience (Cracking Ser.)
by Jon TurneyFor so long, the brain was the great unknown of human biology; an evolved complex of cells, chemicals and electricity, which eluded even the understanding of its own grey matter. Now, in this comprehensive guide, the most complicated concepts from across the field of neuroscience - such as memory, addiction and mind mapping - are broken down into easily understandable bite-sized pieces, to give everyone the chance to understand their own brain. Includes sections on:-The anatomy of the brain-Neurons, synapses and axons - the building blocks of the brain-Differences in male and female development-Modern treatment of mental illness-The effects on the brain of different food and stimulants-Memory, senses, cravings-Fight or flight-Perception and sensation-The future of neuroscience
Cracking Phenomena in Welds IV
by John C. Lippold Thomas Boellinghaus Carl Edward CrossThis is the fourth volume inthe well-established series of compendiums devoted to the subject of weld hotcracking. It contains the papers presented at the 4th InternationalCracking Workshop held in Berlin in April 2014. In the context of thisworkshop, the term "cracking" refers to hot cracking in the classical andprevious sense, but also to cold cracking, stress-corrosion cracking andelevated temp. solid-state cracking. A variety of different crackingsubjects are discussed, including test standards, crack prediction, weldabilitydetermination, crack mitigation, stress states, numerical modelling, andcracking mechanisms. Likewise, many different alloys were investigatedsuch as aluminum alloys, copper-aluminum dissimilar metal, austenitic stainlesssteel, nickel base alloys, duplex stainless steel, creep resistant steel, andhigh strength steel.
Cracking Quantum Physics
by Brian CleggEnter the invisible world of sub-atomic physics and discover the very core of existence. Cracking Quantum Physics takes you through every area of particle physics to clearly explain how our world was, and is, created, and breaks down the most complex theories into easily understandable elements. Subjects covered include:-Time travel-The Higgs field-Dark Matter-The anatomy of the elements-Enter the atom-Quantum reality-Quantum tunnelling-Electrodynamics-Accelerators and colliders-The Zeno effectAn easy-to-understand guide to some of the most complex and intriguing topics: Cracking Quantum Physics is a must-read for anyone who has ever wondered about the underlying forces and materials that make up the world as we know it.
Cracking Quantum Physics (Cracking Ser.)
by Brian CleggEnter the invisible world of sub-atomic physics and discover the very core of existence. Cracking Quantum Physics takes you through every area of particle physics to clearly explain how our world was, and is, created, and breaks down the most complex theories into easily understandable elements. Subjects covered include:-Time travel-The Higgs field-Dark Matter-The anatomy of the elements-Enter the atom-Quantum reality-Quantum tunnelling-Electrodynamics-Accelerators and colliders-The Zeno effectAn easy-to-understand guide to some of the most complex and intriguing topics: Cracking Quantum Physics is a must-read for anyone who has ever wondered about the underlying forces and materials that make up the world as we know it.
Cracking the Aging Code: The New Science of Growing Old—and What It Means for Staying Young
by Dorion Sagan Josh MitteldorfA revolutionary examination of why we age, what it means for our health, and how we just might be able to fight it.In Cracking the Aging Code, theoretical biologist Josh Mitteldorf and award-winning writer and ecological philosopher Dorion Sagan reveal that evolution and aging are even more complex and breathtaking than we originally thought. Using meticulous multidisciplinary science, as well as reviewing the history of our understanding about evolution, this book makes the case that aging is not something that “just happens,” nor is it the result of wear and tear or a genetic inevitability. Rather, aging has a fascinating evolutionary purpose: to stabilize populations and ecosystems, which are ever-threatened by cyclic swings that can lead to extinction. When a population grows too fast it can put itself at risk of a wholesale wipeout. Aging has evolved to help us adjust our growth in a sustainable fashion as well as prevent an ecological crisis from starvation, predation, pollution, or infection.This dynamic new understanding of aging is provocative, entertaining, and pioneering, and will challenge the way we understand aging, death, and just what makes us human.
Cracking the AP Biology Exam, 2010 Edition
by Kim MagloireIn their Cracking the AP Exam guides, the Princeton Review team offers preparation strategies and test-taking techniques to raise scores, advice on how to focus only on the subject's topics that are likely to be covered on the test, and full-length practice tests--with explanations and answers for every question.
Cracking the AP Biology Exam, 2013 Edition (Revised)
by Princeton ReviewIf you need to know it, it's in this book! This eBook version of the revised 2013 edition of Cracking the AP Biology Exam has been optimized for on-screen viewing with cross-linked questions, answers, and explanations, and includes: * 2 full-length practice tests with detailed explanations * An overview of the subject matter changes made to the 2013 AP Biology Exam * A comprehensive biology test topic review, covering everything from photosynthesis to genetics to evolution * Strategies for the new grid-in and short free-response question types * Review questions and key term lists in every chapter to help you practice * Detailed guidance on how to write a topical, cohesive, point-winning essay