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Curious George Discovers the Seasons
by H. A. ReyThe seasons are changing and winter is closing in. George has toys for warm weather and toys for snowy weather—but what’s a monkey to do when winter days are just plain cold? When he decides to ignore the weather and play with his wading pool and bubbles, George learns some interesting things about weather, temperature, and freezing and melting. Learn all about the four seasons with your favorite monkey! Based on the Emmy-winning PBS show, this story is filled to the brim with additional facts, real photos, experiments, activities, and more. Learning about science has never been so much fun!
Curious George and the Kite (CGTV Reader)
by H. A. ReyCurious George loves a good windy day. There are many things he can practice flying-like a kite. Now if only he doesn't get too carried away! This early reader explores the concepts of flight and experimentation.
Curious George and the Rocket (Curious George Ser.)
by Margret ReyGeorge takes a giant leap for monkeykind when he gets suited up and blasts off into space in this out-of-this-world interplanetary adventure.This lively story captures George’s adventure of becoming the first space monkey from the classic Curious George Gets a Medal.Praise for the Curious George books“What distinguishes the George stories is where the trouble is—almost never in a person, never in humanity. George lives in a super benign world, even if it is often strange and unfamiliar to him. This is different than living in a world that is familiar but crowded with evil or indifference . . . George is at once an impossible monkey, a fantasy, and also, simply, one of us.” —The New Yorker“Curious George certainly deserves a spot on the shelf, and these engaging stories will provide a good exercise in imagination and creativity.” —The Horn Book
Curious George: Wash Your Hands (Curious George Ser.)
by H. A. Rey H. A. ReyLearn to wash the germs off your hands with Curious George in this playful and informative book for the youngest readers. When should Curious George wash his hands? Why does George wash his hands . . . and how does he do it? Join George on a playful romp through his day as he learns more about germs and hand-washing. This accessible story features informational text about germs and cleanliness for the youngest readers. This is the perfect primer for little ones just learning to wash their hands.
Curious Learners in Primary Maths, Science, Computing and DT
by Alan Cross Jon Board Jon Chippindall Karen Beswick Alison BorthwickWhether it is in the National Curriculum or the Teachers' Standards, promotion of children's curiosity is highlighted as a key part of effective teaching. Curiosity has the potential to enhance learning in all curriculum subjects but it has a special connection with scientific thinking. A curious approach can open up learning in science, computing, design technology and mathematics. This text explores how teachers can harness the power of curiosity in their classroom. Full of practical teaching ideas for engaging learners and making lessons more exciting, it highlights the ways in which STEM subjects can be taught together. Coverage includes: the place of curiosity in subject teaching how curiosity contributes to a learner's overall capability examples of curiosity in primary STEM classes case studies which exemplify curiosity.
Curious Learners in Primary Maths, Science, Computing and DT
by Alan Cross Jon Board Jon Chippindall Karen Beswick Alison BorthwickWhether it is in the National Curriculum or the Teachers′ Standards, promotion of children′s curiosity is highlighted as a key part of effective teaching. Curiosity has the potential to enhance learning in all curriculum subjects but it has a special connection with scientific thinking. A curious approach can open up learning in science, computing, design technology and mathematics. This text explores how teachers can harness the power of curiosity in their classroom. Full of practical teaching ideas for engaging learners and making lessons more exciting, it highlights the ways in which STEM subjects can be taught together. Coverage includes: the place of curiosity in subject teaching how curiosity contributes to a learner′s overall capability examples of curiosity in primary STEM classes case studies which exemplify curiosity.
Curious Minds: How a Child Becomes a Scientist
by John BrockmanA fascinating collection of essays from twenty-seven of the world's most interesting scientists about the moments and events in their childhoods that set them on the paths that would define their lives. What makes a child decide to become a scientist? *For Robert Sapolsky--Stanford professor of biology--it was an argument with a rabbi over a passage in the Bible. *Physicist Lee Smolin traces his inspiration to the volume of Einstein's work he picked up as a diversion from heartbreak. *Mihaly Csikszentmihalyi, a psychologist and the author of Flow, found his calling through Descartes. *Mary Catherine Bateson--author of Composing a Life--discovered that she wanted to be an anthropologist while studying Hebrew. *Janna Levin--author of How the Universe Got Its Spots--felt impelled by the work of Carl Sagan to know more. Murray Gell-Mann, Nicholas Humphrey, Freeman Dyson, Daniel C. Dennett, Lynn Margulis, V. S. Ramachandran, Howard Gardner, Richard Dawkins, and more than a dozen others tell their own entertaining and often inspiring stories of the deciding moment. Illuminating memoir meets superb science writing in essays that invite us to consider what it is--and isn't--that sets the scientific mind apart and into action.
Curious Minds: The Power of Connection
by Perry Zurn Dani S. BassettAn exhilarating, genre-bending exploration of curiosity&’s powerful capacity to connect ideas and people.Curious about something? Google it. Look at it. Ask a question. But is curiosity simply information seeking? According to this exhilarating, genre-bending book, what&’s left out of the conventional understanding of curiosity are the wandering tracks, the weaving concepts, the knitting of ideas, and the thatching of knowledge systems—the networks, the relations between ideas and between people. Curiosity, say Perry Zurn and Dani Bassett, is a practice of connection: it connects ideas into networks of knowledge, and it connects knowers themselves, both to the knowledge they seek and to each other. Zurn and Bassett—identical twins who write that their book &“represents the thought of one mind and two bodies&”—harness their respective expertise in the humanities and the sciences to get irrepressibly curious about curiosity. Traipsing across literatures of antiquity and medieval science, Victorian poetry and nature essays, as well as work by writers from a variety of marginalized communities, they trace a multitudinous curiosity. They identify three styles of curiosity—the busybody, who collects stories, creating loose knowledge networks; the hunter, who hunts down secrets or discoveries, creating tight networks; and the dancer, who takes leaps of creative imagination, creating loopy ones. Investigating what happens in a curious brain, they offer an accessible account of the network neuroscience of curiosity. And they sketch out a new kind of curiosity-centric and inclusive education that embraces everyone&’s curiosity. The book performs the very curiosity that it describes, inviting readers to participate—to be curious with the book and not simply about it.
Curious Science of Bodily Fluids: Discover What's Floating Around Inside of You!
by Åsmund EikenesFascinating details on everyday fluids!In The Curious Science of Bodily Fluids, readers meet, among others, a brain researcher, a urologist and a chef. They share stories and personal experiences, which together with the latest from the world of research offer startling, new knowledge about body fluids. Some of the revelations include: The water in the brain washes away rubbish while you sleep. The mucus in the cervix helps healthy sperm to reach the egg. Tiny drops of snot can float in the air for a full ten minutes after a strong sneeze. The blood of young people may contain a source of eternal life.And many more!The perfect gift for those interested in popular science!
Curious Species: How Animals Made Natural History
by Whitney Barlow RoblesA compelling and innovative exploration of how animals shaped the field of natural history and its ecological afterlives Can corals build worlds? Do rattlesnakes enchant? What is a raccoon, and what might it know? Animals and the questions they raised thwarted human efforts to master nature during the so-called Enlightenment—a historical moment when rigid classification pervaded the study of natural history, people traded in people, and imperial avarice wrapped its tentacles around the globe. Whitney Barlow Robles makes animals the unruly protagonists of eighteenth-century science through journeys to four spaces and ecological zones: the ocean, the underground, the curiosity cabinet, and the field. Her forays reveal a forgotten lineage of empirical inquiry, one that forced researchers to embrace uncertainty. This tumultuous era in the history of human-animal encounters still haunts modern biologists and ecologists as they struggle to fathom animals today. In an eclectic fusion of history and nature writing, Robles alternates between careful historical investigations and probing personal narratives. These excavations of the past and present of distinct nonhuman creatures reveal the animal foundations of human knowledge and show why tackling our current environmental crisis first requires looking back in time.
Curious2018: Future Insights in Science and Technology
by Ulrich A. K. BetzThis book expands the debate on the future of science and technology at the Curious2018 – Future Insight Conference, held on the occasion of Merck’s 350-year anniversary. In the respective chapters, some of the world’s top scientists, managers and entrepreneurs explore breakthrough technologies and how they can be applied to make a better world for humanity.Divided into three parts, the book begins with an introduction to the vision of the conference and to the importance of curiosity for innovation, while also exploring the latest scientific developments that are shaping the future of healthcare, medicine, the life and material sciences, digitalization and new ways of working together. In the second part, particular attention is paid to new therapies and diagnostics; here, readers will learn how synthetic biology and chemistry are being used to solve problems that are essential to the future of humanity. The role of in-silico research is also discussed. In the final part of the book, readers will find some thoughts on ethical principles guiding our application of science and technology to create a bright future for humanity.Given its interdisciplinary appeal, the book will inspire curiosity in a wide readership, from scholars and researchers to professionals with an interest in exploring the future of science and technology, solving the problems of today, and paving the way for a better tomorrow.Chapters 1, 2, 3 and 17 are available open access under a Creative Commons Attribution-NonCommercial 4.0 International License via link.springer.com.
Curious: The Desire to Know and Why Your Future Depends on It
by Ian LeslieA fascinating multi-disciplinary analysis of why curiosity makes the world go round.'A lovely, erudite exploration of what it is that makes us human' - Independent on Sunday'I have no special talents. I am only passionately curious' Albert Einstein. Everyone is born curious. But only some retain the habits of exploring, learning and discovering as they grow older. Which side of the 'curiosity divide' are you on? In Curious Ian Leslie makes a passionate case for the cultivation of our desire to know. Curious people tend to be smarter, more creative and more successful. But at the very moment when the rewards of curiosity have never been higher, it is misunderstood and undervalued, and increasingly practised only by a cognitive elite. Drawing on fascinating research from psychology, sociology and business, Curious looks at what feeds curiosity and what starves it, and uncovers surprising answers. Curiosity isn't a quality you can rely on to last a lifetime, but a mental muscle that atrophies without regular exercise. It's not a gift, but a habit that parents, schools, workplaces and individuals need to nurture if it is to thrive. Filled with inspiring stories, case studies and practical advice, Curious will change the way you think about your own mental life, and that of those around you.
Curious: The Desire to Know and Why Your Future Depends on It
by Ian LeslieA fascinating multi-disciplinary analysis of why curiosity makes the world go round.'A lovely, erudite exploration of what it is that makes us human' - Independent on Sunday'I have no special talents. I am only passionately curious' Albert Einstein. Everyone is born curious. But only some retain the habits of exploring, learning and discovering as they grow older. Which side of the 'curiosity divide' are you on? In Curious Ian Leslie makes a passionate case for the cultivation of our desire to know. Curious people tend to be smarter, more creative and more successful. But at the very moment when the rewards of curiosity have never been higher, it is misunderstood and undervalued, and increasingly practised only by a cognitive elite. Drawing on fascinating research from psychology, sociology and business, Curious looks at what feeds curiosity and what starves it, and uncovers surprising answers. Curiosity isn't a quality you can rely on to last a lifetime, but a mental muscle that atrophies without regular exercise. It's not a gift, but a habit that parents, schools, workplaces and individuals need to nurture if it is to thrive. Filled with inspiring stories, case studies and practical advice, Curious will change the way you think about your own mental life, and that of those around you.(P)2020 Quercus Editions Limited
Currants, Gooseberries, and Jostaberries: A Guide for Growers, Marketers, and Researchers in North America
by Kim Hummer Danny BarneyRediscover the economic potential of growing Ribes cultivars in the United States and Canada! Currants, Gooseberries, and Jostaberries: A Guide for Growers, Marketers, and Researchers in North America explores the biology and history of growing these small fruits as commercial crops in North America. This book provides authoritative inf
Currency Control (The Gamer)
by Shawn PryorEvil Cynthia Cyber is robbing banks with her latest creation, a villain named Currency. The stolen money will go toward building a machine that can capture people in a simulation program. There she could control every victim’s life. It's up to the Gamer to stop Cynthia Cyber from taking over the world!
Current Advances in Biotechnological Production of Xylitol: Fermentative Production of Xylitol
by Anuj Kumar Chandel Maria das Graças de Almeida FelipeThis book explores recent advances in the microbial production of xylitol and its applications in food and medical sector. Xylitol is an important biomolecule from lignocellulose biorefinery which is produced from the xylose by chemical reactions or microbial fermentation methods. Currently, the demand of xylitol at commercial scale is being met through chemical methods. However, recent breakthroughs made in plant cell wall destruction, genetic engineering to develop the designer microorganisms, fermentation methods and media formulations and downstream processing have led the ways for sustainable production of xylitol at commercial scale in lignocellulose biorefineries. Microbial production of xylitol is preferred over the chemical processes as it is environmentally friendly, higher process efficiency with the desired product yield, and product recovery with minimum impurities. This book is a unique compilation of 11 book chapters written by experts in their respective fields. These chapters present critical insights and discuss the current progress and future progress in this area into fermentative xylitol production.Chapter 9 is licensed under the terms of the Creative Commons Attribution 4.0 International License. For further details see license information in the chapter.
Current Advances in Fern Research
by Helena FernándezFerns, collectively, represent an ancient species of vascular plant which has a direct connection to the beginning of life on Earth. Today they are valued for their ornamental appeal, environmental benefit or as sources of health benefiting metabolites. Current pteridology, the study of fern, encompasses a wide range of research activities including, but not limited to, plant physiology, stress tolerance, genetics and genomics. The goal of this book is to compile the most relevant research done with ferns during the last decade. It is organized into four parts: I, Biology and Biotechnology; II, Evolution and Conservation; III, Metabolism and Genetic Resources, and IV, Environment. Each section reveals the utilization of ferns as a tool to explore challenges unique to plant development and adaptation.This project represents our collective effort to raise the awareness of ferns as a model system to study higher plant functions. Among the distinctive features of our proposed book are: (i) a wide range of topics with contributing researchers from all around the world, and (ii) recent advances of theoretic and applied knowledge with implications to crop species of economic value.
Current Advances in Mechanical Engineering: Select Proceedings of ICRAMERD 2020 (Lecture Notes in Mechanical Engineering)
by Saroj Kumar Acharya Dipti Prasad MishraThis book presents select proceedings of the International Conference on Recent Advances in Mechanical Engineering Research and Development (ICRAMERD 2020). The contents focus on latest research and current problems in various branches of mechanical engineering. Some of the topics discussed here include fracture and failure analysis, fuels and alternative fuels, combustion and IC engines, advanced manufacturing technologies, powder metallurgy and rapid prototyping, industrial engineering and automation, supply chain management, design of mechanical systems, vibrations and control engineering, automobile engineering, fluid mechanics and machines, heat transfer, composite materials, micro and nano-engineering for energy storage and conversion, and modeling and simulations. The wide range of topics presented in this book can make it useful for beginners, researchers as well as professionals in mechanical engineering.
Current Advances in Oral and Craniofacial Tissue Engineering
by Vincenzo Guarino and Marco Antonio Alvarez-PérezOral tissue engineering involves the study of current approaches for in vitro regeneration of soft and hard tissues located into the oral cavity. In this context, recent approaches involves the use of innovative biomaterials to replace the lost or damaged human oral tissues. Recent discoveries in materials science and nanotechnology are drastically changing the traditional approach to dentistry by the design of innovative devices able more efficiently supporting the natural regeneration process. The objective of this book is to highlight current progress in tissue engineering for various dental hard/soft tissues including enamel, dentin, pulp, alveolar bone, periodontium, gum and oral mucosa, by emphasizing the role of materials and their specific applications.
Current Advances in Osteosarcoma: Clinical Perspectives: Past, Present and Future (Advances in Experimental Medicine and Biology #1257)
by Eugenie S. Kleinerman Richard GorlickThis thoroughly revised second edition complied in 2 books is an up-to-date overview of the current clinical advances in sarcoma and osteosarcoma. The new edition features detailed, in-depth discussions of microRNAs in osteosarcoma, historical perspectives of chemotherapy in the treatment of the disease, tumor targeted IL12 therapy and HER2 targeted therapy, the role of enhancer elements in regulating the prometastatic transcriptional program and more. Further, these essential volumes also includes new insights on Wnt signaling in osteosarcoma, the role of genomics, genetically modified T-cell therapy, liquid biopsy, oncolytic viruses, immunophenotyping, receptor tyrosine kinases and epigenetic-focused approaches for treatment of osteosarcoma metastases, as well as thoughts on the current standard of treatment for patients suffering from these cancers. In the years since the previous edition, there have been numerous new developments in this rapidly changing field; this new edition is both timely and urgently needed. When taken together these companion volumes, Current Clinical (Book 1) and Scientific (Book 2) Advances in Osteosarcoma, are a timely and urgently needed guide for laboratory investigators and clinical oncologists focused in sarcoma.
Current Advances in the Science of Osteosarcoma: Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and Canine Models (Advances in Experimental Medicine and Biology #1258)
by Eugenie S. Kleinerman Richard GorlickThis thoroughly revised second edition is an up-to-date overview of the new advances in the knowledge of the basic science in sarcoma and osteosarcoma. It features detailed, in-depth discussions of microRNAs in osteosarcoma, historical perspectives of chemotherapy in the treatment of the disease, tumor targeted IL12 therapy and HER2 targeted therapy, the role of enhancer elements in regulating the prometastatic transcriptional program and more. Further, this essential volume also includes new insights on Wnt signaling in osteosarcoma, the role of genomics, genetically modified T-cell therapy, liquid biopsy, oncolytic viruses, immunophenotyping, receptor tyrosine kinases and epigenetic-focused approaches for treatment of osteosarcoma metastases, as well as thoughts on the current standard of treatment for patients suffering from these cancers. In the years since the previous edition, there have been numerous new developments in this rapidly changing field; this new edition is both timely and urgently needed. When taken together these companion volumes, Current Clinical (Book 1) and Scientific (Book 2) Advances in Osteosarcoma, are a timely and urgently needed guide for laboratory investigators and clinical oncologists.
Current Antipsychotics (Handbook of Experimental Pharmacology #212)
by Gerhard Gross Mark A. GeyerSix decades after the serendipitous discovery of chlorpromazine as an antipsychotic and four decades after the launch of clozapine, the first atypical or second generation antipsychotic, psychopharmacology has arrived at an important crossroad. It is clear that pharmacological research and pharmaceutical development must now focus on complementary or even alternative mechanisms of action to address unmet medical needs, i.e. poorly treated domains of schizophrenia, improved acceptance by patients, better adherence to medication, safety in psychoses in demented patients, and avoiding cardiac and metabolic adverse effects. The first completely novel mechanisms evolving from our insights into the pathophysiology of psychotic disorders, especially the role of glutamatergic mechanisms in schizophrenia, are now under development, and further principles are on the horizon. This situation, in many respects similar to that when the initial second-generation antipsychotics became available, can be rewarding for all. Preclinical and clinical researchers now have the opportunity to confirm their hypotheses and the pharmaceutical industry may be able to develop really novel classes of therapeutics. When we were approached by the publishers of the Handbook of Experimental Pharmacology to prepare a new volume on antipsychotics, our intention was to capture both, the accumulated preclinical and clinical knowledge about current antipsychotics as well as prospects for new and potentially more specific antischizophrenia principles. These efforts should be based on the pathophysiology of the diseases and the affected neurotransmitter systems. Since preclinical research on antipsychotic compounds is only reliable when intimately linked through translational aspects to clinical results, we decided to include clinical science as well. It turned out that that this endeavor could not be covered by a single volume. We thank the editorial board and the publishers for supporting our decision to prepare two volumes: Current Antipsychotics and Novel Antischizophrenia Treatments. These topics cannot really be separated from one another and should be seen as a composite entity despite the somewhat arbitrary separation of contributions into two volumes. The continuing challenges of developing improved and safer antipsychotic medications remain of concern and are discussed in the first volume. The new opportunities for the field to develop and license adjunctive treatments for the negative symptoms and cognitive deficits that are treated inadequately by existing compounds have been incentivized recently and provide the focus for the second volume. We hope these collective contributions will facilitate the development of improved treatments for the full range of symptomatology seen in the group of schizophrenias and other major psychotic disorders. Gerhard Gross, Ludwigshafen, Germany Mark A. Geyer, La Jolla, CA This volume will try to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters will also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. Non-schizophrenia indications will be covered to some extent, but not exhaustively.
Current Applications for Overcoming Resistance to Targeted Therapies (Resistance to Targeted Anti-Cancer Therapeutics #20)
by Myron R. Szewczuk Bessi Qorri Manpreet SambiTargeted therapies were initially developed to exploit the upregulation and dependence on key oncogenic pathways critical to cancer progression. Additionally, they also presented as a method to overcome chemoresistance by supplementing conventional therapeutic regimens with targeted therapies. However, the development of resistance to these combinatorial approaches has led to the reassessment of currently available therapeutic options to overcome resistance to targeted therapy. This book aims to provide an update on the advancements in the therapeutic arms race between cancer, clinicians and scientists alike to overcome resistance to targeted therapies. Subject experts provide a comprehensive overview of the challenges and solutions to resistance to several conventional targeted therapies in addition to providing a discussion on broad topics including targeting components of the tumor microenvironment, emerging therapeutic options, and novel areas to be explored concerning nanotechnology and the epigenome.
Current Applications of Deep Learning in Cancer Diagnostics
by Jyotismita Chaki Aysegul UcarThis book examines deep learning-based approaches in the field of cancer diagnostics, as well as pre-processing techniques, which are essential to cancer diagnostics. Topics include introduction to current applications of deep learning in cancer diagnostics, pre-processing of cancer data using deep learning, review of deep learning techniques in oncology, overview of advanced deep learning techniques in cancer diagnostics, prediction of cancer susceptibility using deep learning techniques, prediction of cancer reoccurrence using deep learning techniques, deep learning techniques to predict the grading of human cancer, different human cancer detection using deep learning techniques, prediction of cancer survival using deep learning techniques, complexity in the use of deep learning in cancer diagnostics, and challenges and future scopes of deep learning techniques in oncology.
Current Applications of Pharmaceutical Biotechnology (Advances in Biochemical Engineering/Biotechnology #171)
by Ana Catarina Silva João Nuno Moreira José Manuel Sousa Lobo Hugo AlmeidaThis book offers an authoritative review of biopharmaceuticals and their clinical relevance. Biopharmaceuticals have been showing high therapeutic potential by means of biological and biosimilar medicines, particularly for the treatment of cancer, chronic diseases (e.g. diabetes, Crohn's disease, psoriasis and rheumatoid arthritis), neurodegenerative disorders (e.g. multiple sclerosis), and they have also been contributing to the progress of innovative therapies such as assisted reproductive medicine. Since the eighties, several biopharmaceuticals have been approved and, due to patents expiration, many biosimilars are also marketed.In this book, readers will find the most relevant updated information about the main clinical applications of pharmaceutical biotechnology. The authors provide expert analysis about the industrial challenges of recombinant proteins and the different classes of biopharmaceuticals, including monoclonal antibodies, vaccines, growth factors and stem cells. Topics such as bioprinting technologies in tissue engineering, gene therapy and personalized medicine are also covered in this book. Professionals, students and researchers interested in this field will find this work an important account.