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De-Sequencing: Identity Work with Genes (Health, Technology and Society)
by Dana Mahr Martina Von ArxAre you your genes? De-Sequencing: Identity Work with Genes explores this perplexing question, showing how different forms of knowledge must be contextualized to become meaningful. It is generally assumed that the genomic sequence adds up to the identity-forming material life is made of. Yet identity cannot itself adopt the form of a sequence. As the authors in this volume show, the genome must be ‘de-sequenced’ by human language to render it interpretable and meaningful in a social context. The book unpacks this type of ‘sequence-speech’ in engaging detail, adopting a personal, social, cultural, and bio-political approach to examine the transformation of human identity and reflexivity in the era of genetic citizenship.
The de Sitter: An Introduction to Elementary Systems and Modeling the Dark Energy Universe (Synthesis Lectures on Mathematics & Statistics)
by Mohammad Enayati Jean-Pierre Gazeau Hamed Pejhan Anzhong WangThis book reviews the construction of elementary systems living in de Sitter (dS) spacetime, in both the classical and quantum senses. Field theories on dS spacetime are among the most studied mathematical models of the Universe, whether for its earlier period (inflationary phase) or for its current phase of expansion acceleration (dark energy or cosmological constant). Classical elementary systems are Hamiltonian phase spaces, which are associated with co-adjoint orbits of the relativity group. On the other hand, quantum elementary systems are associated with (projective) unitary irreducible representations of the (possibly extended) relativity group (or one of its covering). This study emphasizes the conceptual issues arising in the formulation of such systems and discusses known results in a mathematically rigorous way. Particular attention is paid to: “smooth” transition from classical to quantum theory; physical content under vanishing curvature, from the point of view of a local (“tangent”) Minkowskian observer; and thermal interpretation (on the quantum level), in the sense of the Gibbons-Hawking temperature. Such a mathematical construction is of paramount importance to the understanding of the early Universe (due to the critical role that the dS metric plays in the inflationary cosmological scenarii) as well as to the construction of possible models for late-time cosmology (since a small positive cosmological constant or dark energy seems to be required by recent data). In this sense, this book uniquely blends mathematical physics (spacetime symmetry on classical and quantum levels) and theoretical physics (quantization, quantum field theory, and cosmology). Moreover, the level of exposition varies in different parts of the book so that both experts and beginners alike can utilize the book.
The de Sitter: An Introduction to Elementary Systems and Modeling the Dark Energy Universe (Synthesis Lectures on Mathematics & Statistics)
by Mohammad Enayati Jean-Pierre Gazeau Hamed Pejhan Anzhong WangThis Second Edition is a comprehensive update, integrating the latest research and theoretical advancements in the field of de Sitter (dS) group representations. Building on the success of the first edition, the book offers a more in-depth analysis of mathematical aspects, conceptual foundations, and practical implications related to the dS group, including its Lie manifold, Lie algebra, and co-adjoint orbits, viewing the latter as potential classical elementary systems within the context of dS spacetime. Additionally, the examination of unitary irreducible representations (UIRs) sheds light on the potential existence of quantum elementary systems within the dS spacetime framework. The authors emphasize consistency with Wigner's approach to elementary systems, incorporate Wigner's principles and exploring projective UIRs of the dS group, and provide a deeper insight into the nature of dS elementary systems. Particular attention is paid to: the “smooth” transition from classical to quantum theory, the physical content under vanishing curvature, and the thermal interpretation from a quantum perspective. The book also focuses on the physical interpretation of elementary systems in curved spacetimes, recognizing the limitations of traditional concepts derived from flat Minkowski spacetime and the Poincaré group.
De sphaera of Johannes de Sacrobosco in the Early Modern Period: The Authors of the Commentaries
by Matteo VallerianiThis open access book explores commentaries on an influential text of pre-Copernican astronomy in Europe. It features essays that take a close look at key intellectuals and how they engaged with the main ideas of this qualitative introduction to geocentric cosmology. Johannes de Sacrobosco compiled his Tractatus de sphaera during the thirteenth century in the frame of his teaching activities at the then recently founded University of Paris. It soon became a mandatory text all over Europe. As a result, a tradition of commentaries to the text was soon established and flourished until the second half of the 17th century. Here, readers will find an informative overview of these commentaries complete with a rich context. The essays explore the educational and social backgrounds of the writers. They also detail how their careers developed after the publication of their commentaries, the institutions and patrons they were affiliated with, what their agenda was, and whether and how they actually accomplished it. The editor of this collection considers these scientific commentaries as genuine scientific works. The contributors investigate them here not only in reference to the work on which it comments but also, and especially, as independent scientific contributions that are socially, institutionally, and intellectually contextualized around their authors.
DE ZIEKTE VAN ALZHEIMER III
by Luc Wyn Juan Moises de la SernaBoek beschrijving Hoe wordt ze behandeld? Hoe verspreidt ze zich? Hoe kan ze voorkomen worden? Leer meer over de laatste vorderingen en de behandeling van de ziekte van Alzheimer. Enkele van de voornaamste aspecten van een ziekte zijn hoe ze te overwinnen, of er een geneeswijze bestaat en wat de behandeling is. Er worden constant vorderingen geboekt met betrekking tot onderzoek naar de behandeling en preventie van de ziekte van Alzheimer, welke in deze tekst worden toegelicht. Doel: Het doel van dit boek is een eerste kennismaking te verlenen aan diegenen die zelf de ziekte van ALZHEIMER hebben of een familielid hebben dat eraan lijdt. Dit boek tracht op duidelijke wijze de resultaten van de meest recente research over de ziekte van Alzheimer naar voren te brengen, met het oog op het beantwoorden van de meest relevante vragen: Hoe behandelt men ze? Hoe is de voortgang? Hoe wordt ze voorkomen? Doelpubliek: - Personeel in de gezondheidssector dat zich wenst te verdiepen in de diagnose en de behandeling van de ziekte van Alzheimer. - Professoren die hun studenten bijgewerkte informatie over de ziekte van Alzheimer willen bieden. - Éénieder die een diagnose van de ziekte van Alzheimer ontving en hun familie zodat zij weten wat te doen met betrekking tot deze ziekte. Thema’s Hierna wordt elk van de hoofdthema’s van dit uiteen gezet: - Behandeling van Alzheimer: Ondanks de beperkte effectiviteit van de bestaande behandelings vormen, worden er elke dag nieuwe ontdekkingen gedaan gericht op het omgaan met deze ziekte. - Voortgang van Alzheimer: De ziekte van Alzheimer wordt gezien als een progressieve ziekte, wat betekent dat ze mettertijd de cognitieve vaardigheden doet verliezen van diegenen die eraan lijden. Ontdek hoe men dit bestrijdt. - Voorkoming van Alzheimer: Dit is misschien één van de minst bekende aspecten van de de meest recente ontdekkingen
Dead Center: Behind the Scenes at the World's Largest Medical Examiner's Office
by Shiya Ribowsky Tom ShachtmanThis insider’s account of the NYC medical examiner’s office takes readers from an average day in the autopsy room to the tragic aftermath of 9/11.For fifteen years, Shiya Ribowsky worked as a medicolegal investigator in New York City’s medical examiner’s office—the largest, most sophisticated organization of its kind in the world. Ribowsky led the investigations of more than eight thousand individual deaths, becoming a key figure in some of New York’s most bizarre death cases. He also took charge of the largest forensic investigation ever attempted: identifying the dead in the aftermath of September 11th.Now Ribowsky pulls back the curtain on the New York City’s medical examiner’s office, giving a never-before-seen glimpse into death and the city. From vermin-infested Bowery flophouses to posh Upper East Side apartments of the city’s dead, Ribowsky explores the skeletons that hang in the Big Apple’s closets. Combing through the autopsy room, he also exposes the grim secrets that only a scalpel can reveal, and explains how forensic investigation not only solve crimes—but also saves lives.
Dead Meat: Competing Vitalities, Cultivated Meat Imaginaries and Anthropocene Diets
by Elisabeth AbergelAs we confront the environmental challenges of the Anthropocene, cellular agriculture has emerged as a revolutionary technology promising to reshape global food systems. Dead Meat offers a critical examination of this biotechnological shift, exploring how cultivated meat production reconfigures the relationship between life, death, and food in the context of competing ecological, social, and ethical imperatives. Elisabeth Abergel provides a compelling analysis of cultivated meat through the lens of “competing vitalities”, questioning how these new forms of food production are narrated and imagined in the Anthropocene. She delves into the sociotechnical imaginaries that promise sustainability, animal welfare, and climate resilience, while probing the tensions between these narratives and the political economy of industrial food production. Drawing on interdisciplinary perspectives from the environmental humanities, science and technology studies, political economy, and political ecology, Abergel critiques the idea that cultivated meat is a simple technological fix to the climate crisis. Instead, she exposes how these innovations both challenge and reinforce capitalist logics that dominate agricultural systems. Dead Meat is essential reading for scholars and students in environmental sociology, food politics, science and technology studies, environmental humanities, and political economy, as well as for activists and policymakers interested in sustainable food futures and planetary health.
Dead Men Do Tell Tales: The Strange and Fascinating Cases of a Forensic Anthropologist
by Michael Browning William R. MaplesFrom a skeleton, a skull, a mere fragment of burnt thighbone, Dr. William Maples can deduce the age, gender, and ethnicity of a murder victim, the manner in which the person was dispatched, and, ultimately, the identity of the killer. In Dead Men Do Tell Tales, Dr. Maples revisits his strangest, most interesting, and most horrific investigations, from the baffling cases of conquistador Francisco Pizarro and Vietnam MIAs to the mysterious deaths of President Zachary Taylor and the family of Czar Nicholas II.From the Trade Paperback edition.
Dead Reckoning
by Mercedes Lackey Rosemary EdghillJett is a girl disguised as a boy, living as a gambler in the old West as she searches for her long-lost brother. Honoria Gibbons is a smart, self-sufficient young woman who also happens to be a fabulous inventor. Both young women travel the prairie alone - until they are brought together by a zombie invasion! As Jett and Honoria investigate, they soon learn that these zombies aren't rising from the dead of their own accord ... but who would want an undead army? And why? This gunslinging, hair-raising, zombie western mashup is perfect for fans ofCowboys vs. Aliens and Pride & Prejudice & Zombies.
Dead Reckoning: Air Traffic Control, System Effects, and Risk
by Diane VaughanVaughan unveils the complicated and high-pressure world of air traffic controllers as they navigate technology and political and public climates, and shows how they keep the skies so safe. When two airplanes were flown into the World Trade Center towers on September 11, 2001, Americans watched in uncomprehending shock as first responders struggled to react to the situation on the ground. Congruently, another remarkable and heroic feat was taking place in the air: more than six hundred and fifty air traffic control facilities across the country coordinated their efforts to ground four thousand flights in just two hours—an achievement all the more impressive considering the unprecedented nature of the task. In Dead Reckoning, Diane Vaughan explores the complex work of air traffic controllers, work that is built upon a close relationship between human organizational systems and technology and is remarkably safe given the high level of risk. Vaughan observed the distinct skill sets of air traffic controllers and the ways their workplaces changed to adapt to technological developments and public and political pressures. She chronicles the ways these forces affected their jobs, from their relationships with one another and the layouts of their workspace to their understanding of their job and its place in society. The result is a nuanced and engaging look at an essential role that demands great coordination, collaboration, and focus—a role that technology will likely never be able to replace. Even as the book conveys warnings about complex systems and the liabilities of technological and organizational innovation, it shows the kinds of problem-solving solutions that evolved over time and the importance of people.
Deadenylation: Methods and Protocols (Methods in Molecular Biology #2723)
by Eugene Valkov Aaron C. GoldstrohmThis volume provides new approaches and technologies into roles of poly(A) metabolism in translation, RNA stability, and quality control of gene expression. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Deadenylation: Methods and Protocols aims to pave the way for future investigations of the complex regulatory networks that control mRNA stability and expression.
Deadliest!: 20 Dangerous Animals (Extreme Animals)
by Steve JenkinsWhat do a cape buffalo, a king cobra, and a puffer fish have in common? They're all deadly! Deadliest! showcases some of the planet’s most threatening creatures. Steve Jenkins's Extreme Animals reader series explores nature's truly superlative animals with the help of illustrations, infographics, facts, and figures while detailing the astounding abilities of critters as small as a frog or as big as a whale. Each installment focuses on truly amazing and unusual animals, making these nonfiction readers accessible, informative, and fascinating.
The Deadliest Diseases Then and Now (The Deadliest)
by Deborah HopkinsonPerfect for young readers of I Survived and the Who Was series! Packed with graphics, photos, and facts for curious minds, this is a gripping look at pandemics through the ages.The deadly outbreak of plague known as the Great Mortality, which struck Europe in the mid 1300s and raged for four centuries, wiped out more than 25 million people in the course of just two years. With its vicious onslaught, life changed for millions of people almost instantaneously.Deadly pandemics have always been a part of life, from the Great Mortality of the Middle Ages, to the Spanish Influenza outbreak of 1918, to the eruption of COVID-19 in our own century. Many of these diseases might have seemed like things to read about in history books -- until the unthinkable happened, and our own lives were turned upside down by the emergence of the novel coronavirus.As we learn more about COVID-19, we may be curious about pandemics of the past. Knowing how humans fought diseases long ago may help us face those of today. In this fast-paced, wide-ranging story filled with facts, pictures, and diagrams about diseases -- from plague to smallpox to polio to flu -- critically acclaimed Sibert Honor author Deborah Hopkinson brings voices from the past to life in this exploration of the deadliest diseases of then and now. Filled with more than 50 period photographs and illustrations, charts, facts, and pull-out boxes for eager nonfiction readers.
Deadliest Enemy: Our War Against Killer Germs
by Mark Olshaker Michael OsterholmWe are facing an overwhelming army of deadly, invisible enemies. We need a plan -- before it's too late.Unlike natural disasters, whose destruction is concentrated in a limited area over a period of days, and illnesses, which have devastating effects but are limited to individuals and their families, infectious disease has the terrifying power to disrupt everyday life on a global scale, overwhelming public and private resources and bringing trade and transportation to a grinding halt. In today's world, it's easier than ever to move people, animals, and materials around the planet, but the same advances that make modern infrastructure so efficient have made epidemics and even pandemics nearly inevitable. And as outbreaks of Ebola, MERS, yellow fever, and Zika have demonstrated, we are woefully underprepared to deal with the fallout. So what can -- and must -- we do in order to protect ourselves from mankind's deadliest enemy? <P><P>Drawing on the latest medical science, case studies, policy research, and hard-earned epidemiological lessons, Deadliest Enemy explores the resources and programs we need to develop if we are to keep ourselves safe from infectious disease. The authors show how we could wake up to a reality in which many antibiotics no longer cure, bioterror is a certainty, and the threat of a disastrous influenza pandemic looms ever larger. Only by understanding the challenges we face can we prevent the unthinkable from becoming the inevitable. <P><P>Deadliest Enemy is high scientific drama, a chronicle of medical mystery and discovery, a reality check, and a practical plan of action. <P><P><b>A New York Times Bestseller</b>
Deadly Choices: How the Anti-vaccine Movement Threatens Us All
by Paul A. OffitThere's a silent, dangerous war going on out there. On one side are parents, bombarded with stories about the dangers of vaccines, now wary of immunizing their sons and daughters. On the other side are doctors, scared to send kids out of their offices vulnerable to illnesses like whooping cough and measles--the diseases of their grandparents.How did anyone come to view vaccines with horror? The answer is rooted in one of the most powerful citizen activist movements in our nation's history. In Deadly Choices, infectious disease expert Paul Offit relates the shocking story of anti-vaccine America--its origins, leaders, influences, and impact. Offering strategies to keep us from returning to an era when children routinely died from infections, Deadly Choices is a vigorous and definitive rebuttal of the powerful anti-vaccine movement.
Deadly Companions: How Microbes Shaped Our History
by Dorothy H. CrawfordBeginning with a dramatic account of the SARS pandemic at the start of the 21st century, she takes us back in time to follow the interlinked history of microbes and man, taking an up-to-date look at ancient plagues and epidemics, and identifying key changes in the way humans have lived - such as our move from hunter-gatherer to farmer to city-dweller - which made us vulnerable to microbe attack.
Deadly Cultures: Biological Weapons since 1945
by Lajos RózsaThe threat of biological weapons has never attracted as much public attention as in the past five years. Current concerns largely relate to the threat of weapons acquisition and use by rogue states or by terrorists. But the threat has deeper roots—it has been evident for fifty years that biological agents could be used to cause mass casualties and large-scale economic damage. Yet there has been little historical analysis of such weapons over the past half-century. Deadly Cultures sets out to fill this gap by analyzing the historical developments since 1945 and addressing three central issues: Why have states continued or begun programs for acquiring biological weapons? Why have states terminated biological weapons programs? How have states demonstrated that they have truly terminated their biological weapons programs? We now live in a world in which the basic knowledge needed to develop biological weapons is more widely available than ever before. Deadly Cultures provides the lessons from history that we urgently need in order to strengthen the long-standing prohibition of biological weapons.
Deadly Design
by Debra DockterThe emotional power of If I Stay meets the survival story of Maze Runner Genetically engineered identical twins Kyle and Connor McAdams were born two years apart. Their parents figured it was safer that way, to increase their odds of survival. Connor was born first, paving an impossibly perfect path for Kyle to follow. He was the best at everything--valedictorian, star quarterback etc. Kyle never thought he'd be able to live up, so he didn't even try. But when Connor, 18, suddenly drops dead of a heart attack, and Kyle learns of other genetically modified kids who've also died on their eighteenth birthdays, he's suddenly motivated--to save his own life. Like Connor and all the rest, Kyle was conceived at the Genesis Innovations Laboratory, where the mysterious Dr. Mueller conducted experiments on them. The clock's ticking as Kyle searches for answers: who was Dr. Mueller really, and what did he do to cause their hearts to stop at eighteen? He must unravel the clues quickly, before, he too, becomes another perfect, blue-eyed corpse.
The Deadly Dinner Party & Other Medical Detective Stories
by Jonathan A. EdlowPicking up where Berton Roueché's The Medical Detectives left off, The Deadly Dinner Party presents fifteen edge-of-your-seat, real-life medical detective stories written by a practicing physician. Award-winning author Jonathan Edlow, M. D. , shows the doctor as detective and the epidemiologist as elite sleuth in stories that are as gripping as the best thrillers. In these stories a notorious stomach bug turns a suburban dinner party into a disaster that almost claims its host; a diminutive woman routinely eats more than her football-playing boyfriend but continually loses weight; a young executive is diagnosed with lung cancer, yet the tumors seem to wax and wane inexplicably. Written for the lay person who wishes to better grasp how doctors decipher the myriad clues and puzzling symptoms they often encounter, each story presents a very different case where doctors must work to find the accurate diagnosis before it is too late. Edlow uses his unique ability to relate complex medical concepts in a writing style that is clear, engaging and easily understandable. The resulting stories both entertain us and teach us much about medicine, its history and the subtle interactions among pathogens, humans, and the environment.
Deadly Feasts: Tracking the Secrets of a Terrifying New Plague
by Richard RhodesRichard Rhodes follows virus hunters on three continents as they track the emergence of a deadly new brain disease that first kills cannibals in New Guinea, then cattle and young people in Britain and France -- and that has already been traced to food animals in the United States. In a new Afterword for the paperback, Rhodes reports the latest U. S. and worldwide developments of a burgeoning global threat.
Deadly Glow: The Radium Dial Worker Tragedy
by Ross MullnerDeadly Glow: The Radium Dial Worker Tragedy
Deadly Outbreaks: How Medical Detectives Save Lives Threatened by Killer Pandemics, Exotic Viruses, and Drug-Resistant Parasites
by Alexandra LevittDespite advances in health care, infectious microbes continue to be a formidable adversary to scientists and doctors. Vaccines and antibiotics, the mainstays of modern medicine, have not been able to conquer infectious microbes because of their amazing ability to adapt, evolve, and spread to new places. Terrorism aside, one of the greatest dangers from infectious disease we face today is from a massive outbreak of drug-resistant microbes.Deadly Outbreaks recounts the scientific adventures of a special group of intrepid individuals who investigate these outbreaks around the world and figure out how to stop them. Part homicide detective, part physician, these medical investigators must view the problem from every angle, exhausting every possible source of contamination. Any data gathered in the field must be stripped of human sorrows and carefully analyzed into hard statistics.Author Dr. Alexandra Levitt is an expert on emerging diseases and other public health threats. Here she shares insider accounts she's collected that go behind the alarming headlines we've seen in the media: mysterious food poisonings, unexplained deaths at a children's hospital, a strange neurologic disease afflicting slaughterhouse workers, flocks of birds dropping dead out of the sky, and drug-resistant malaria running rampant in a refugee camp. Meet the resourceful investigators--doctors, veterinarians, and research scientists--and discover the truth behind these cases and more.
Deadly Predators (Readers)
by Melissa StewartCome face-to-face with sharks, wolves, tigers, and many more predators in this gripping new addition to the National Geographic Kids Reader series. Amazing animal photos will wow kids as they discover how predators hunt, raise their young, and contribute to the food chain. This Level 2 reader is written in easy-to-grasp text and will help kids understand who rules in the wild!
A Deadly Wandering
by Matt RichtelA landmark exploration of the vast and expanding impact of technology, rivetingly told through the lens of a deadly collisionOne of the year's most original and masterfully reported books, A Deadly Wandering by Pulitzer Prize-winning New York Times journalist Matt Richtel interweaves the cutting-edge science of attention with the tensely plotted story of a mysterious car accident and its aftermath to answer some of the defining questions of our time: What is technology doing to us? Can our minds keep up with the pace of change? How can we find balance? Through Richtel's beautifully constructed narrative, a complex and far-reaching topic becomes intimate and urgent--an important call to reexamine our own lives.On the last day of summer, an ordinary Utah college student named Reggie Shaw fatally struck two rocket scientists while texting and driving along a majestic stretch of highway bordering the Rocky Mountains. Richtel follows Reggie from the moment of the tragedy, through the police investigation, the state's groundbreaking prosecution (at the time there was little precedent to guide the court), and ultimately, Reggie's wrenching admission of responsibility. Richtel parallels Reggie's journey with leading-edge scientific findings regarding human attention and the impact of technology on our brains--showing how these devices, now thoroughly embedded into all aspects of our lives, play to our deepest social instincts and prey on parts of the brain that crave stimulation, creating loops of compulsion, even addiction. Remarkably, today Reggie is a leading advocate who has helped spark a national effort targeting distracted driving, and the arc of his story provides a window through which Richtel pursues actionable solutions to help manage this crisis individually and as a society. A propulsive read filled with fascinating scientific detail, riveting narrative tension, and rare emotional depth, A Deadly Wandering is a book that can change--and save--lives.
Dealing with Aging Process Facilities and Infrastructure
by CcpsExamines the concept of aging process facilities and infrastructure in high hazard industries and highlights options for dealing with the problem while addressing safety issues This book explores the many ways in which process facilities, equipment, and infrastructure might deteriorate upon continuous exposure to operating and climatic conditions. It covers the functional and physical failure modes for various categories of equipment and discusses the many warning signs of deterioration. Dealing with Aging Process Facilities and Infrastructure also explains how to deal with equipment that may not be safe to operate. The book describes a risk-based strategy in which plant leaders and supervisors can make more informed decisions on aging situations and then communicate them to upper management effectively. Additionally, it discusses the dismantling and safe removal of facilities that are approaching their intended lifecycle or have passed it altogether. Filled with numerous case studies featuring photographs to illustrate the positive and negative experiences of others who have dealt with aging facilities, Dealing with Aging Process Facilities and Infrastructure covers the causes of equipment failures due to aging and their consequences; plant management commitment and responsibility; inspection and maintenance practices for managing life cycle; specific aging asset integrity management practices; and more. Describes symptoms and causal mechanisms of aging in various categories of process equipment Presents key considerations for making informed risk-based decisions regarding the repair or replacement of aging process facilities and infrastructure Discusses practices for managing process facility and infrastructure life cycle Includes examples and case histories of failures related to aging Dealing with Aging Process Facilities and Infrastructure is an important book for industrial practitioners who are often faced with the challenge of managing process facilities and infrastructure as they approach the end of their useful lifecycle.