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Developing Bioinformatics Computer Skills
by Per Jambeck Cynthia GibasBioinformatics--the application of computational and analytical methods to biological problems--is a rapidly evolving scientific discipline. Genome sequencing projects are producing vast amounts of biological data for many different organisms, and, increasingly, storing these data in public databases. Such biological databases are growing exponentially, along with the biological literature. It's impossible for even the most zealous researcher to stay on top of necessary information in the field without the aid of computer-based tools. Bioinformatics is all about building these tools. Developing Bioinformatics Computer Skills is for scientists and students who are learning computational approaches to biology for the first time, as well as for experienced biology researchers who are just starting to use computers to handle their data. The book covers the Unix file system, building tools and databases for bioinformatics, computational approaches to biological problems, an introduction to Perl for bioinformatics, data mining, and data visualization. Written in a clear, engaging style, Developing Bioinformatics Computer Skills will help biologists develop a structured approach to biological data as well as the tools they'll need to analyze the data.
Developing Biomedical Devices
by Giuseppe Andreoni Massimo Barbieri Barbara ColomboDuring the past two decades incredible progress has been achieved in the instruments and devices used in the biomedical field. This progress stems from continuous scientific research that has taken advantage of many findings and advances in technology made available by universities and industry. Innovation is the key word and in this context legal protection and intellectual property rights (IPR) are of crucial importance. This book provides students and practitioners with the fundamentals for designing biomedical devices and explains basic design principles. Furthermore, as an aid to the development of devices and products for healthcare, it presents a brief description of the human body, covering anatomy and physiology, that will assist the reader in understanding the origin of biosignals, their significance and the technology to be used in their measurement. Issues concerning IPR and protections are also fully discussed, with examples and opportunities for IPR exploitation.
Developing Capacities for Teaching Responsible Science in the MENA Region
by National Research Council Division on Earth and Life Studies Committee on Developing a Framework for an International Faculty Development Project on Education About Research in the Life Sciences with Dual Use Potential Board on Life Science The World Academy of SciencesSpurred on by new discoveries and rapid technological advances, the capacity for life science research is expanding across the globe--and with it comes concerns about the unintended impacts of research on the physical and biological environment, human well-being, or the deliberate misuse of knowledge, tools, and techniques to cause harm. This report describes efforts to address dual use issues by developing institutes around the world that will help life sciences faculty learn to teach about the responsible conduct of science. Based on the successful National Academies Summer Institute for Undergraduate Biology Education and on previous NRC reports on effective methods for teaching about dual use issues, the report's authoring committee designed a general framework for the faculty institutes and chose the Middle East-North Africa (MENA) region to test a prototype faculty institute. In September 2012, the first Institute was held in Aqaba, Jordan, bringing together 28 participants from Algeria, Egypt, Jordan, Libya, and Yemen to engage with effective, evidence-based teaching methods, develop curricular materials for use in their own classrooms, and become community leaders on dual use and related topics. Developing Capacities for Teaching Responsible Science in the MENA Region: Refashioning Scientific Dialogue offers insights from the institute that will help in the design and implementation of future programs in the MENA region, and in other parts of the world.
Developing Climate Resilient Grain and Forage Legumes
by Harsh Nayyar Kadambot H. M. Siddique Uday C Jha Shiv Kumar AgrawalThis edited book covers all aspects of grain legumes including negative impact of abiotic and biotic stresses under the changing global climate. It discusses the role of various subject disciplines ranging from plant breeding, genetics, plant physiology, molecular biology, and genomics to high-throughput phenotyping and other emerging technologies for sustaining global grain and fodder legume production to alleviate impending global food crises. The book offers strategies to ensure plant-based dietary protein security across the globe. It covers all major commercial legume crops used as food, feed and fodder. This book is targeted to graduate and postgraduate students, researchers, progressive farmers and policymakers to inform them of the importance of cultivating grain and fodder legumes for future global food and nutritional security and for maintaining sustainable ecosystem.
Developing Climate-Resilient Crops: Improving Global Food Security and Safety (Footprints of Climate Variability on Plant Diversity)
by Shah FahadDeveloping Climate-Resilient Crops: Improving Global Food Security and Safety is timely, as the world is gradually waking up to the fact that a global food crisis of enormous proportions is brewing. Climate change is creating immense problems for agricultural productivity worldwide, resulting in higher food prices. This book elucidates the causative aspects of climate modification related to agriculture, soil, and plants, and discusses the relevant resulting mitigation process and also how new tools and resources can be used to develop climate-resilient crops. Features: Addresses the limits of the anthropogenic global warming theory advocated by the Intergovernmental Panel on Climate Change Presents the main characters (drought tolerance, heat tolerance, water-use efficiency, disease resistance, nitrogen-use efficiency, nitrogen fixation, and carbon sequestration) necessary for climate-resilient agriculture Delivers both theoretical and practical aspects, and serves as baseline information for future research Provides valuable resource for those students engaged in the field of environmental sciences, soil sciences, agricultural microbiology, plant pathology, and agronomy Highlights factors that are threatening future food production
Developing Critical Thinking in Physics: The Apprenticeship of Critique (Contributions from Science Education Research #7)
by Laurence Viennot Nicolas DécampThis book promotes the effective implementation and development of critical analysis in physics. It focuses on explanatory texts concerning subjects typically dealt with in secondary or higher education and addressed in an academic or popular context. It highlights the general difficulties and obstacles inherent in teaching physics and shows how some tools can help to combine successful criticism and better understanding. The book examines the main reasons to call a text into question and looks at risk factors such as simplifications, story-like explanations and visual analogies. It takes inventory of the benefits and limits of critical analysis and discusses the complex links between conceptual mastery and critical attitude. The book ends by offering tools to activate critical thinking and ways for educators to guide students towards productive critical analysis.
Developing Insights in Cartilage Repair
by Pieter J. Emans Lars PetersonThis comprehensive book discusses cartilage repair and all its aspects. These aspects vary from basic insights in cartilage biology and regeneration via MRI, to results of existing cartilage repair techniques and upcoming novel approaches. Fundamental cartilage biology is the topic covered within the first chapters of the book. These chapters not only provide an insight in healthy, damaged and regenerative cartilage but also describe developments in gene therapy and methods to enhance chondrogenesis of stemcells and prevent hypertophic differentiation. There is a huge progress in the possibilities of MR imaging of both healthy, damaged and regenerative cartilage. These developments not only enable better monitoring of cartilage repair but may also unravel the pathophysiology of the development of cartilage defects. Different cartilage repair techniques (e. g. allografts, autologous chondrocytes transplantation [ACT], microfracture), there technical aspects (e. g. developments towards an total arthroscopic approach), pitfalls, and outcomes are reported in the following chapters. In these chapters factors important for the results of cartilage repair such as meniscal repair, patient factors are described. Finally, an overview of novel cartilage repair techniques such as minced cartilage, denovo cartilage and more areas are discussed in this comprehensive addition to the literature.
Developing Modular-Oriented Simulation Models Using System Dynamics Libraries
by Christian K. Karl William IbbsThis SpringerBrief introduces the development and practical application of a module-oriented development framework for domain specific system-dynamic libraries (SDL approach), which can be used in the simulation of multi-causal and dynamic relationships on different levels of an industry, as an example the construction industry. Multidisciplinary research and development teams, scientists from different domains as well as practitioners can develop SDL units from varying perspectives based on this approach. For example, the explanation of the risk situation of a company, the identification and evaluation of project risks, endangered operational procedures on various functional levels, or to improve the understanding of the decision making process in detail. This book is an excellent source for researchers, programmers and practitioners. It enables the development of suitable simulation systems from the beginning and demonstrates that it is possible to connect the development of simulation models and daily work. It provides advanced-level students from different domains with a comprehensive overview and clear understanding of a new and valuable modeling technique.
Developing Novel Spinning Methods to Fabricate Continuous Multifunctional Fibres for Bioapplications (Springer Theses)
by Azadeh MirabediniThis book describes the development of three dimensional electroactive fibres using a novel coaxial wet-spinning approach from organic conductors in combination with non-conducting hydrogel polymers. This book also presents the characterization and evaluation of multiaxial biofibres in terms of mechanical, physical, electrochemical and biological properties, and explores their use in a diverse range of applications including implantable electrodes, drug delivery systems and energy-storage systems.In the first chapter, the author highlights the significance of engineering three dimensional fibres, introduces the involved hydrogels and organic conductors with emphasis on their biomedical application, and collects some of the previously established methods for fabrication of biofibres. In the second chapter, particular attention is given to the overall experimental fabrication methods and characterization analyses conducted in the work. Chapters three to five present the main findings of this work, in which readers will discover how novel hybrid hydrogel fibres with an inner core of chitosan and alginate were prepared and characterized, how graphene was incorporated into coaxial wet-spun biofibres, and how one-dimensional triaxial fibres were developed using a novel coaxial wet-spinning fibre production method and applied as potential battery devices. In the final chapter of this work, the author summarizes the main achievements of the work and outlines some recommendations for future research.
Developing Nucleon Self-Energies to Generate the Ingredients for the Description of Nuclear Reactions (Springer Theses)
by Mack C. AtkinsonThis thesis develops the dispersive optical model into a tool that allows for the assessment of the validity of nuclear reaction models, thereby generating unambiguous removal probabilities of nucleons from valence orbits using the electron-induced proton knockout reaction. These removal probabilities document the substantial quantitative degree in which nuclei deviate from the independent-particle model description. Another outcome reported within is the prediction for the neutron distribution of Ca-40, Ca-48, and Pb-208. The neutron radii of these nuclei have direct relevance for the understanding of neutron stars and are currently the subject of delicate experiments. Unlike other approaches, the current method is consistent with all other relevant data and describes nuclei beyond the independent-particle model. Finally, a new interpretation of the saturation probabilities of infinite nuclear matter is proposed suggesting that the semi-empirical mass formula must be supplemented with a better extrapolation from nuclei to infinite matter.
Developing Reflective Judgment
by Patricia M. King Karen Strohm KitchenerHow do students learn to reason and think about complex issues? This book fills a critical gap in our understanding of along-neglected facet of the critical thinking process: reflective judgment. Drawing on extensive cross-sectional and longitudinal research, King and Kitchener detail the series of stages that lay the foundation for reflective thinking, and they trace the development of reflective judgment through adolescence and adulthood. The authors also describe the implications of the Reflective Judgment Model for working with students in the classroom and beyond--encouraging educators to think differently about interactions with their students and to create ways of more effectively promoting the ability to make reflective judgments.
Developing Scaffolds in Evolution, Culture, and Cognition
by Linnda R. Caporael James R. Griesemer William C. Wimsatt"Scaffolding" is a concept that is becoming widely used across disciplines. This book investigates common threads in diverse applications of scaffolding, including theoretical biology, cognitive science, social theory, science and technology studies, and human development. Despite its widespread use, the concept of scaffolding is often given short shrift; the contributors to this volume, from a range of disciplines, offer a more fully developed analysis of scaffolding that highlights the role of temporal and temporary resources in development, broadly conceived, across concepts of culture, cognition, and evolution. The book emphasizes reproduction, repeated assembly, and entrenchment of heterogeneous relations, parts, and processes as a complement to neo-Darwinism in the developmentalist tradition of conceptualizing evolutionary change. After describing an integration of theoretical perspectives that can accommodate different levels of analysis and connect various methodologies, the book discusses multilevel organization; differences (and reciprocality) between individuals and institutions as units of analysis; and perspectives on development that span brains, careers, corporations, and cultural cycles. Contributors: Colin Allen, Linnda R. Caporael, James Evans, Elihu M. Gerson, Simona Ginsburg, James R. Griesemer, Christophe Heintz, Eva Jablonka, Sanjay Joshi, Shu-Chen Li, Pamela Lyon, Sergio F. Martinez, Christopher J. May, Johann Peter Murmann, Stuart A. Newman, Jeffrey C. Schank, Iddo Tavory, Georg Theiner, Barbara Hoeberg Wimsatt, William C. Wimsatt
Developing Scaffolds in Evolution, Culture, and Cognition (Vienna Series in Theoretical Biology #17)
by Linnda R. Caporael James R. Griesemer William C. WimsattEmpirical and philosophical perspectives on scaffolding that highlight the role of temporal and temporary resources in development across concepts of culture, cognition, and evolution."Scaffolding" is a concept that is becoming widely used across disciplines. This book investigates common threads in diverse applications of scaffolding, including theoretical biology, cognitive science, social theory, science and technology studies, and human development. Despite its widespread use, the concept of scaffolding is often given short shrift; the contributors to this volume, from a range of disciplines, offer a more fully developed analysis of scaffolding that highlights the role of temporal and temporary resources in development, broadly conceived, across concepts of culture, cognition, and evolution.The book emphasizes reproduction, repeated assembly, and entrenchment of heterogeneous relations, parts, and processes as a complement to neo-Darwinism in the developmentalist tradition of conceptualizing evolutionary change. After describing an integration of theoretical perspectives that can accommodate different levels of analysis and connect various methodologies, the book discusses multilevel organization; differences (and reciprocality) between individuals and institutions as units of analysis; and perspectives on development that span brains, careers, corporations, and cultural cycles.ContributorsColin Allen, Linnda R. Caporael, James Evans, Elihu M. Gerson, Simona Ginsburg, James R. Griesemer, Christophe Heintz, Eva Jablonka, Sanjay Joshi, Shu-Chen Li, Pamela Lyon, Sergio F. Martinez, Christopher J. May, Johann Peter Murmann, Stuart A. Newman, Jeffrey C. Schank, Iddo Tavory, Georg Theiner, Barbara Hoeberg Wimsatt, William C. Wimsatt
Developing Senior Navy Leaders
by Bruce Newsome Lawrence M. Hanser Herbert J. Shukiar Louis W. MillerCould U.S. Navy officers be better prepared to become flag officers? This study examines the kinds of expertise required for successful performance in Navy flag billets, and whether recent pools of officers possess this experience. The authors also examine Navy trends over the past decade to identify the types of expertise likely to become more important for Navy leaders in the future.
Developing Strategies For Rangeland Management: A Report Prepared By The Committee On Developing Strategies For Rangeland Management
by Mary KoppalIn a two-year study, the National Academy of Sciences' Committee on Developing Strategies for Rangeland Management examined at length the scientific, political, economic, legal, and social issues arising from the BLM's stewardship role. This book, reporting the findings and recommendations of the NAS committee, contains over eighty professional papers presented at workshops designed to assess forage allocation, inventory of rangeland resources, impact of grazing intensity and specialized grazing systems on the use and value of rangeland, manipulative range improvements, application of socioeconomic techniques to range management decision making, and political and legal aspects of range management.
Developing Sustainability Competences Through Pedagogical Approaches: Experiences from International Case Studies (Strategies for Sustainability)
by Rodrigo Lozano Maria Barreiro-GenThis book is aimed at developing sustainability competences through pedagogical approaches by comparing 15 case studies from 12 countries in 4 continents (Africa, America, Australia, and Europe) analysing how Sustainable Development (SD) is being taught in their courses, which competences are being developed, and which pedagogical approaches are being used to develop the competences. The book brings together practice-based original research on the connection between developing sustainability competences and the pedagogical approaches used, utilizing a framework aimed at helping educators in creating and updating their courses to provide a more complete, holistic, and systemic sustainability education to future leaders, decision makers, educators, and change agents. Compared to previous works addressing SD in education, which often mostly cover tools for improving the sustainability of campus operations, this approach uses assessment tools to uniquely focus on how courses and programmes (i.e. curricula) incorporate SD. Through the case studies, readers will learn about how the 3 major groups of pedagogical approaches have been used: (1) Universal, meaning broadly applicable pedagogies that have been used in many disciplines and contexts; (2) Community and social justice, which are pedagogies developed specifically for use in addressing social justice and community-building; and (3) Environmental education, which are pedagogies emerging from environmental sciences and environmental education practices.
Developing Sustainable Agriculture in Pakistan
by Iqrar Ahmad Khan Muhammad Sarwar KhanAgriculture plays a pivotal role in the economy and development of Pakistan providing food to consumers, raw materials to industries, and a market for industrial goods. Unfortunately, agricultural production is stagnant due to several barriers including a fixed cropping pattern, reliance on a few major crops, a narrow genetic pool, poor seed quality, and a changing climate. In addition, the high cost of production, weak phytosanitary compliance mechanisms, and a lack of cold chain facilities makes Pakistan agriculturally uncompetitive in export markets. Despite all these issues, agriculture is the primary industry in Pakistan and small farmers continue to dominate the business. Small farmers grow crops for subsistence under a fixed cropping pattern and a holistic approach is required to develop agriculture to improve the livelihoods of the rural populace. This book presents an exhaustive look at agriculture in Pakistan. Chapters provide critical analyses of present trends, inadequacies in agriculture, strategic planning, improvement programs and policies while keeping in view the natural resources, plant- and animal-related agricultural production technologies, input supplies, population planning, migration and poverty, and balanced policies on finance, credit, marketing, and trade.
Developing Synthetic Transport Systems
by Alexey Melkikh Maria SutorminaUnderstanding the general laws of an effective system for the transport of substances in cells is an important goal of systems and synthetic biology and will help us to answer why the transport subsystem of a cell is arranged as it is. In addition, the construction of models for optimizing transport systems is of considerable importance in the early stages in the development of a functioning protocell. The aim of this book is to describe the latest techniques for the calculation of the optimal parameters of the transport subsystem of a cell at its maximum efficiency. The book will describe linear and nonlinear programming, dynamic programming, game theory for models of ion transport in different types of cells (e.g. mammalian cells, bacteria, plants and fungi).
Developing The Environment: Problems & Management
by C J BarrowThis book presents a comprehensive overview of global environmental problems - past, present and future - examining their roots and implications and suggesting, where possible, ways in which they might be mitigated or avoided by careful management.
Developing a Cybersecurity Immune System for Industry 4.0
by Sergei PetrenkoCyber immune systems try to mimic the adaptive immune system of humans and animals because of its capability to detect and fend off new, unseen pathogens. Today's current cyber security systems provide an effective defense mechanism against known cyber-attacks but are not so good when it comes to defending against unknown attacks. This book describes the possible development and organization of self-healing computing based on cyber immunity techniques and aimed at working in the new realm of Industry 4.0. Industry 4.0 is the trend towards automation and data exchange in manufacturing technologies and processes which include cyber-physical systems (CPS), the internet of things (IoT), industrial internet of things (IIOT), cloud computing, cognitive computing and artificial intelligence. The book describes the author’s research and development of cyber-immunity systems that will prevent the destruction of critical information infrastructure by future unknown cyber-attacks and thus avoid the significant or catastrophic consequences of such attacks.The book is designed for undergraduate and post-graduate students, for engineers in related fields as well as managers of corporate and state structures, chief information officers (CIO), chief information security officers (CISO), architects, and research engineers in the field of cybersecurity.This book contains four chapters1. Cyber Immunity Concept of the Industry 4.0; 2. Mathematical Framework for Immune Protection of Industry 4.0; 3. Trends and prospects of the development of Immune Protection of Industry 4.0; 4. From detecting cyber-attacks to self-healing Industry 4.0;
Developing a Model of Islamic Psychology and Psychotherapy: Islamic Theology and Contemporary Understandings of Psychology (Routledge Research in Psychology)
by Abdallah RothmanAt a time when there is increasing need to offer psychotherapeutic approaches that accommodate clients’ religious and spiritual beliefs, and acknowledge the potential for healing and growth offered by religious frameworks, this book explores psychology from an Islamic paradigm and demonstrates how Islamic understandings of human nature, the self, and the soul can inform an Islamic psychotherapy. Drawing on a qualitative, grounded theory analysis of interviews with Islamic scholars and clinicians, this unique volume distils complex religious concepts to reconcile Islamic theology with contemporary notions of psychology. Chapters offer nuanced explanations of relevant Islamic tradition and theological sources, consider how this relates to Western notions of psychotherapy and common misconceptions, and draw uniquely on first-hand data to develop a new theory of Islamic psychology. This, in turn, informs an innovative and empirically driven model of practice that translates Islamic understandings of human psychology into a clinical framework for Islamic psychotherapy. An outstanding scholarly contribution to the modern and emerging discipline of Islamic psychology, this book makes a pioneering contribution to the integration of the Islamic sciences and clinical mental health practice. It will be a key resource for scholars, researchers, and practicing clinicians with an interest in Islamic psychology and Muslim mental health, as well as religion, spirituality and psychology more broadly.
Developing a National STEM Workforce Strategy: A Workshop Summary
by Engineering Medicine Policy Joe Alper Board on Higher Education Workforce National Academies of Sciences Global Affairs Planning Committee for the National Summit on Developing a STEM Workforce StrategyThe future competitiveness of the United States in an increasingly interconnected global economy depends on the nation fostering a workforce with strong capabilities and skills in science, technology, engineering, and mathematics (STEM). STEM knowledge and skills enable both individual opportunity and national competitiveness, and the nation needs to develop ways of ensuring access to high-quality education and training experiences for all students at all levels and for all workers at all career stages. The National Science Foundation (NSF) holds a primary responsibility for overseeing the federal government’s efforts to foster the creation of a STEM-capable workforce. As part of its efforts in this endeavor, NSF’s Directorate on Education and Human Resources asked the National Academies of Sciences, Engineering, and Medicine to convene a workshop that would contribute to NSF’s preparation of a theoretical and evidence-based STEM Workforce Development R&D Core Framework. Participants discussed research themes, identified gaps and emerging research opportunities, and recommended refinements in the goals of the framework. This report summarizes the presentations and discussions from the workshop.
Developing a Research Strategy for Suicide Prevention in the Department of Defense: Status of Current Research, Prioritizing Areas of Need, and Recommendations for Moving Forward
by Terri Tanielian Rajeev Ramchand Phoenix Voorhies Nicole K. Eberhart Christopher Guo Eric Pedersen Terrance Dean SavitskyTo support U. S. Department of Defense (DoD) efforts to create a unified, comprehensive strategic plan for suicide prevention research, a RAND study cataloged studies funded by DoD and other entities, examined whether current research maps to DoD's strategic research needs, and provided recommendations to encourage better alignment and narrow the research-practice gap when it comes to disseminating findings to programs serving military personnel.
Developing a Research and Restoration Plan for Arctic-Yukon-Kuskokwim (Western Alaska) Salmon
by Committee on Review of Arctic-Yukon-Kuskokwim (Western Alaska) Research Restoration Plan for SalmonRecent declines in the abundance of salmon in the Arctic-Yukon-Kuskokwim (AYK) region of western Alaska have created hardships for the people and communities who depend on this resource. In 2002, the AYK Sustainable Salmon Initiative (SSI) was created to undertake research to understand the reasons for this decline and to help support sustainable management in the region. This book makes recommendations for developing the research that the AYK SSI science plan should be based on, and relates the development of a restoration plan to the results of that research.