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Development: Mechanisms of Change (Darwin College Lectures #29)
by Torsten Krude Sara T. BakerThis volume collects essays from prominent intellectuals and public figures based on talks given at the 2015 Darwin College Lectures on the theme of 'development'. The writers are world-renowned experts in such diverse fields as architecture, astronomy, biology, climate science, economy, psychology, sports and technology. Development includes contributions from developmental biologist and Nobel laureate John B. Gurdon, Olympic gold medallist Katherine Grainger, astronomer and cosmologist Richard Ellis, developmental psychologist Bruce Hood, former Met Office Chief Scientist Julia Slingo, architect Michael Pawlyn, development economist Ha-Joon Chang and serial entrepreneur Hermann Hauser. While their perspectives and interpretations of development vary widely, their essays are linked by a common desire to describe and understand how things change, usually in the direction of ever-increasing complexity. Written with the lay reader in mind, this interdisciplinary book is a must-read for anybody interested in the mechanisms underlying the changes we see in the world around us.
Development Across The Life Span (Eighth Edition)
by Robert S. FeldmanA compelling blend of lifespan development research and applications Development Across the Life Span provides a chronological overview of human development from the moment of conception through death, examining both the traditional areas of the field and more recent innovations. Author Robert Feldman focuses on how developmental findings can be can be applied meaningfully and practically, helping students to recognize the relevance of the discipline to their own lives. Thoroughly updated with the latest data and contemporary examples, the Eighth Edition better engages students in key concepts via recent news items, timely world events, and contemporary uses of lifespan development. Personalize learning with MyPsychLab MyPsychLab is an online homework, tutorial, and assessment program designed to work with this text to engage students and improve results. Within its structured environment, students practice what they learn, test their understanding, and pursue a personalized study plan that helps them better absorb course material and understand difficult concepts.
Development and Application of Biomarkers (Protein Science)
by Roger L. LundbladFirst introduced to biomedical research in 1980, the term biomarker has taken on a life of its own in recent years and has come to mean a number of things. A comprehensive assessment of biomarkers, this book covers the history and current status of the application of biomarkers in diagnostics and prognostics. It explores the technology used for the study of biomarkers, and the validation of biomarkers including a comparison of the various technologies used to identify and measure biomarkers. The editors emphasize the technology underlying biomarkers and the translation of basic science to clinical laboratory technology, including the commercial development of biomarkers. The book also covers proteomics and proteomic technologies and their applications in the identification of biomarkers.
Development and Applications of Free Electron Lasers
by Jia Chen Hai-Cang Ren Xie Jialin Ming-han YeProvides a comprehensive overview of the field of free electron lasers. Each chapter is based on a graduate-level lecture given by an internationally-known expert in the field, and is self-contained, beginning with introductory background material and culminating in an in-depth discussion of the author's current research. Written with both the student physicist and the active researcher in mind, this book is sure to be an invaluable reference for graduate students and professionals alike.
Development and Applications of Negative Ion Sources (Springer Series on Atomic, Optical, and Plasma Physics #110)
by Vadim DudnikovThis book describes the development of sources of negative ions and their application in science and industry. It describes the physical foundations and implementation of the key methods of negative ion production and control, such as charge exchange, thermionic emission, secondary emission (sputtering) and surface-plasma sources, as well as the history of their development. Following on from this essential foundational material, the book goes on to explore transport of negative ion beams, and beam-plasma instabilities. With exposition accessible at the graduate level, and a comprehensive bibliography, this book will appeal to all students and researchers whose work concerns ion sources and their applications to accelerators, beam physics, storage rings, cyclotrons, and plasma traps.
Development and Applications of Negative Ion Sources (Springer Series on Atomic, Optical, and Plasma Physics #125)
by Vadim DudnikovThis book describes the development of sources of negative ions and their application in science and industry. It describes the physical foundations and implementation of the key methods of negative ion production and control, such as charge exchange, thermionic emission, plasma volume, secondary emission (sputtering) and surface-plasma sources, as well as the history of their development. Following on from this essential foundational material, the book goes on to explore transport of negative ion beams, and beam-plasma instabilities. Now in its second edition, the book has been substantially expanded and updated to address the many developments since it was first published, most importantly the development and investigation of cesiated surfaces with work function ~1.2-1.3 eV in conditions close to discharges in surface plasma sources. The book also includes a new chapter on development of conversion targets for high-energy neutral beam injectors, covering gas targets, plasma targets and photon targets for efficient conversion of high energy negative ion beams to neutral beams.With exposition accessible at the graduate level, and a comprehensive bibliography, this book will appeal to all students and researchers whose work concerns ion sources and their applications to accelerators, beam physics, storage rings, cyclotrons, and plasma traps.
Development and Characterization of a Dispersion-Encoded Method for Low-Coherence Interferometry
by Christopher TaudtThis Open Access book discusses an extension to low-coherence interferometry by dispersion-encoding. The approach is theoretically designed and implemented for applications such as surface profilometry, polymeric cross-linking estimation and the determination of thin-film layer thicknesses. During a characterization, it was shown that an axial measurement range of 79.91 µm with an axial resolution of 0.1 nm is achievable. Simultaneously, profiles of up to 1.5 mm in length were obtained in a scan-free manner. This marked a significant improvement in relation to the state-of-the-art in terms of dynamic range. Also, the axial and lateral measurement range were decoupled partially while functional parameters such as surface roughness were estimated. The characterization of the degree of polymeric cross-linking was performed as a function of the refractive index. It was acquired in a spatially-resolved manner with a resolution of 3.36 x 10-5. This was achieved by the development of a novel mathematical analysis approach.
Development and Evaluation of Drugs: From Laboratory through Licensure to Market
by Chi Jen Lee Cheng-Hsiung Lu Lucia H. LeeSince its initial publication in 1993, Development and Evaluation of Drugs from Laboratory through Licensure to Market has been used as a textbook and reference for scientists in biomedical research, industry, and regulatory agencies. Updated and expanded, this second edition examines recent advances in scientific and regulatory approaches as well
Development and Quantification of Sustainability Indicators (Environmental Footprints And Eco-design Of Products And Processes)
by Subramanian Senthilkannan MuthuThis book highlights various methods for quantifying sustainability indicators using different indices. To date, numerous sustainability indicators encompassing either all three pillars (economic, environmental and social) or individual or joint indicators (e.g. environmental and social) have been developed and quantified. In addition to commonly developed indicators, which can be utilized for any industrial sector, sector-specific sustainability indicators are frequently used. Behind each indicator developed, there is a unique scientific model, method or assessment technique. This book explores and elaborates on such indicators, and on associated details such as the concept, development methodology, assessment technique, and applications of each indicator.
Development and Reproduction in Humans and Animal Model Species
by Werner A. Mueller Monika Hassel Maura GrealyThis book describes human development including sexual reproduction and stem cell research with the development of model organisms that are accessible to genetic and experimental analysis in readily understandable texts and 315 multi-colored graphics. The introductory account of model organisms selected from the entire animal kingdom presents general principles, which are then outlined in subsequent chapters devoted to, for example, sexual development; genes controlling development and their contemporary molecular-analysis methods; production of clones and transgenic animals; development of the nervous and circulatory systems; regenerative medicine and ageing. Finally the evolution of developmental toolkits and novelties is discussed including the genetic basis of the enlargement of the human forebrain. Separate boxes are devoted to controversial questions such as the benefits and problems of prenatal diagnostics or the construction of ancient body plans.
Development and Testing of Hand Exoskeletons (Springer Theses)
by Matteo BianchiThis book describes the development of portable, wearable, and highly customizable hand exoskeletons to aid patients suffering from hand disabilities. It presents an original approach for the design of human hand motion assistance devices that relies on (i) an optimization-based kinematic scaling procedure, which guarantees a significant adaptability to the user’s hands motion, and (ii) a topology optimization-based design methodology, which allowed the design of a lightweight, comfortable device with a high level of performance. The book covers the whole process of hand exoskeleton development, from establishing a new design strategy, to the construction and testing of hand exoskeleton prototypes, using additive manufacturing techniques. As such, it offers timely information to both researchers and engineers developing human motion assistance systems, especially wearable ones.
Development and Testing of Vehicle Software and its Influence on Sustainable Transport
by Antonio Colmenar-Santos David Borge-Diez Pedro-Miguel Ortega-CabezasThis book evaluates the contributions of the electronic control unit software of an electric vehicle on sustainability and society, such as the reduction of emissions during a product design and the improvements in the vehicle. A sustainable transport model is proposed, demonstrating its economic viability. By validating software in a more efficient way and adding new functionalities to the software to enhance driving efficiency, energy consumption can be significantly reduced. Therefore, software validation and development have a significant impact on sustainability. This book offers innovative validation solutions based on artificial intelligence techniques to reduce validation time and emissions. The impact of driving efficiency on sustainable transport models is studied in detail, making proposals to be considered in the current environmental policies under discussion within the European Union in order to improve the sustainability of transport models. Vehicles are becoming sophisticated electronic systems due to the fact that they are integrating a significant number of electronic control units. This trend will certainly continue in the year to come. Consequently, software validation techniques are a key element for car manufacturers in order to ensure the quality of the vehicle. This book contributes to these efforts.
Development and Uses of Biofortified Agricultural Products
by Gary S. Bañuelos Zhi-Qing LinAlthough ending world hunger remains the most important goal, increasingly the focus is on simultaneously improving world malnutrition. Paradoxically, nutritionally important trace elements essential for human health are both deficient and over-abundant in soils in many regions of the world. Using a multidisciplinary approach, Development and Uses
Development Cooperation Policy in Forestry from an Analytical Perspective
by Peter AurenhammerAny reader eager to gain a comprehensive insight into forest development policy, praxis and reality shouldn't miss this excellent publication. Hard to find a comparable reading where the author is digging as deep into Forest Development Policy. The author discovered numerous highly relevant theories as well as inspiring cases about forests and people from around the world, focusing on 'change' rather than 'development' and on the role of various actors in creating or preventing 'change'. The exciting results uncover reality and lead to inspiring discussions on concepts of development cooperation. All individual theoretical arguments and empirical proofs are well based and shed light into the political process of Forest Development Policy. The book is an essential contribution to scholarly debate and research on forestry in the South, and its relations to development cooperation, for both, readers with theoretical and practice related interests.
Development in E-waste Management: Sustainability and Circular Economy Aspects
by Biswajit Debnath Abhijit Das Potluri Anil Chowdary Siddhartha BhattacharyyaThis book concerns the developments in the field of e-waste management with a particular focus on urban mining, sustainability, and circular economy aspects. It explains e-waste recycling technologies, supply chain aspects, and e-waste disposal in IT industries, including health and environmental effects of e-waste recycling processes, and associated issues, challenges, and solutions. Further, it describes the economic potential of resource recovery from e-waste. Features: Covers recent developments in e-waste management Explores technological advances, such as nanotech from e-waste, MREW, fungal biotech, and so forth Reviews electronic component recycling aspects Discusses the implementation of circular economy in the e-waste sector Includes urban mining and sustainability aspects of e-waste This book is aimed at graduate students and researchers in environmental engineering, waste management, urban mining, circular economy, waste processing, electronics, and telecommunication engineering, electrical and electronics engineering, and chemical engineering.
Development, Inclusion and Sustainability: Issues and Perspectives (Sustainable Development Goals Series)
by Abhinav Alakshendra Amrita Datta Bhim ReddyThis book addresses the overarching theme of promoting inclusive and sustainable development through twelve contributions that discuss perspectives from emerging economies and policies for a better world. The contributions are divided into four sections -- Employment and Livelihoods; Capabilities and Mobilities; Sustainable and Inclusive Urbanization; and Perspectives for Policies. The first section contains two chapters that deal with employment and labour markets. In the second section, there are four contributions that discuss capabilities (education and health) and their roles in intergenerational mobility, contributing to poverty reduction and inclusive development. The third section comprises of four chapters concerning various aspects of urbanisation in diverse empirical contexts. And the last section consists of two contributions providing policy perspectives. The volume is thus a diverse mix of empirical research and provides critical insights into the Global South’s development process. It is an important reference for all those concerned with sustainable and inclusive development.
Development of 15 Micron Cutoff Wavelength HgCdTe Detector Arrays for Astronomy (Springer Theses)
by Mario CabreraThis thesis describes advances in the understanding of HgCdTe detectors. While long wave (15 μm) infrared detectors HgCdTe detectors have been developed for military use under high background irradiance, these arrays had not previously been developed for astronomical use where the background irradiance is a billion times smaller. The main pitfall in developing such arrays for astronomy is the pixel dark current which plagues long wave HgCdTe. The author details work on the success of shorter wavelength development at Teledyne Imaging Sensors, carefully modeling the dark current–reverse bias voltage curves of their 10 μm devices at a temperature of 30K, as well as the dark current–temperature curves at several reverse biases, including 250 mV. By projecting first to 13 and then 15 μm HgCdTe growth, values of fundamental properties of the material that would minimize tunneling dark currents were determined through careful modeling of the dark current-reverse bias voltage curves, as well as the dark current-temperature curves. This analysis was borne out in the 13 μm parts produced by Teledyne, and then further honed to produce the necessary parameters for the 15 μm growth. The resulting 13 μm arrays are being considered by a number of ground-based astronomy research groups.
Development of a New Heterocycle-Forming Reaction and Kinetic Resolution with N-Heterocyclic Carbenes (Springer Theses)
by Yinli WangIn this book, the author focuses on exploring new organocatalytic transformations under operationally simple and environmentally friendly reaction conditions. Two new types of catalytic reactions promoted by N-heterocyclic carbenes (NHCs) are described. The oxa- and azacycle-forming reactions of sulfonylalkynols and sulfonylalkynamides are broadly considered to be a new type of activation mode in NHC chemistry, wherein the bond formation with internal O- and N-nucleophiles occurs at the γ-position of the propargyl sulfones with 1,2-sulfonyl migration. The resulting oxa- and azacycles are core structures in many biologically significant compounds and medicinally important agents. In addition, the book develops the chiral NHC-catalyzed kinetic resolution of α-hydroxy carboxylic acid derivatives based on chiral recognition of the substrate–cocatalyst complex. In this carboxylate cocatalyst-assisted chiral acylation, the reaction rate acceleration and selectivity enhancement are interpreted in terms of the reversible complexation of the substrate and carboxylate cocatalyst, which is verified by control experiments and measured using analytical methods. The findings described here reveal a promising new aspect of not only NHC catalysis but also identifying novel catalysis systems.
Development of a Numerical Simulation Method for Rocky Body Impacts and Theoretical Analysis of Asteroidal Shapes (Springer Theses)
by Keisuke SugiuraThis book describes numerical simulations of collisions between asteroids, based on a unique numerical code developed by the author. The code accurately solves the elastic dynamic equations and describes the effects of fracture and friction, which makes it possible to investigate the shapes of impact outcomes produced by asteroid collisions and subsequent gravitational accumulation of fragments.The author parallelizes the code with high parallelization efficiency; accordingly, it can be used to conduct high-resolution simulations with the aid of supercomputers and clarify the shapes of small remnants produced through the catastrophic destruction of asteroids. The author demonstrates that flat asteroids can only be produced by impacts involving objects with similar mass and low velocity, which suggests that the flat asteroids in our solar system were created in the planet formation era and have kept their shapes until today. The author also shows that asteroid collisions under certain conditions can produce the extremely elongated shape of an interstellar minor body, 1I/‘Oumuamua. In brief, the book offers a comprehensive investigation of asteroid impacts and shapes, making it a uniquely valuable resource.
Development of a Sub-glacial Radio Telescope for the Detection of GZK Neutrinos
by Thomas MeuresThe goal of the project presented in this book is to detect neutrinos created by resonant interactions of ultrahigh energy cosmic rays on the CMB photon field filling the Universe. In this pioneering first analysis, the author puts forward much of the analysis framework, including calibrations of the electronic hardware and antenna geometry, as well as the development of algorithms for event reconstruction and data reduction. While only two of the 37 stations planned for the Askaryan Radio Array were used in this assessment of 10 months of data, the analysis was able to exclude neutrino fluxes above 10 PeV with a limit not far from the best current limit set by the IceCube detector, a result which establishes the radio detection technique as the path forward to achieving the massive volumes needed to detect these ultrahigh energy neutrinos.
Development of Advanced Nano-Optics: For Miniaturized Optical Set-Ups and Instrumentation
by A. Guillermo BracamonteThis book discusses advanced nano-optics, from proof of concepts to real applications in devices and miniaturized instrumentation. It covers various themes and topics within nanochemistry and physics that produce enhanced optical and smart responsive materials.Development of Advanced Nano-Optics is about the development of nano-optics with advanced nanochemistry control in order to adjust physical phenomena towards new advanced and enhanced properties and related applications. It explores the development of various physical phenomena, such as the generation of high-frequency electromagnetic fields in the near field show, that have an effect in the far field. The author discusses nano-optoelectronics, light scattering nano-optics, quantum nano-optics, and advances in nanospectroscopy. He also presents proof of concepts from nanochemistry and nano-optics towards advanced applications in nanotechnology and the life sciences. Nano-optical materials in microdevices and miniaturized instrumentation are also presented and discussed.This book is written for a wide range of readers, from undergraduate students to advanced researchers, academics, and practising engineers in industry working in the fields of optics, miniaturized instrumentation, and materials.
The Development of Agricultural Science in Northern Italy in the Late Eighteenth and Early Nineteenth Century (Italian and Italian American Studies)
by Martino Lorenzo FagnaniThe late eighteenth century and subsequent Napoleonic Era witnessed a turning point in the establishment of agricultural science as a well-defined discipline in northern Italy. In this book, Martino Lorenzo Fagnani traces these developments by reviewing the correspondence of naturalists and agriculturists as well as the research plans of universities, academies, societies, institutes, and governments. He explores the establishment of a broad knowledge network encompassing all of Europe while also investigating the reasons behind the exchange of seeds, the establishment of spaces for experimentation such as scientific gardens and experimental fields, and the organization of specialized journals and monographs. This work represents an important contribution to the historiography of Italian agricultural science, filling a significant gap in our knowledge of related developments.
The Development of an Aquatic Habitat Classification System for Lakes
by W.D.N. BuschIn the context of freshwater fisheries changing their strategies from the regulation of harvest and the enhancement of populations, to the creation and protection of habitats and the management of ecosystems, moves toward establishing an aquatic habitat classification system. Eight papers, from the February 1988 Symposium on the Classification and Inventory of Great Lakes Aquatic Habitats (the last in a series of Great Lakes Symposia), propose various classification approaches, most using a limited number of physical, chemical, and/or biological variables to produce some form of index. They also include overviews and summaries of the classification process.
Development of an Efficient Modelling Approach to Support Economically and Socially Acceptable Flood Risk Reduction in Coastal Cities: Can Tho City, Mekong Delta, Vietnam (IHE Delft PhD Thesis Series)
by Hieu Quang NgoFlooding is one of the most frequently occurring and damaging natural disasters worldwide. Quantitative flood risk management (FRM) in the modern context demands statistically robust approaches (e.g. probabilistic) due to the need to deal with complex uncertainties. However, probabilistic estimates often involve ensemble 2D model runs resulting in large computational costs.Additionally, modern FRM necessitates the involvement of a broad range of stakeholders via co-design sessions. This makes it necessary for the flood models, at least at a simplified level, to be understood by and accessible to non-specialists. This study was undertaken to develop a flood modelling system that can provide rapid and sufficiently accurate estimates of flood risk within a methodology that is accessible to a wider range of stakeholders for a coastal city – Can Tho city, Mekong Delta, Vietnam. A web-based hydraulic tool, Inform, was developed based on a simplified 1D model for the entire Mekong Delta, flood hazard and damage maps, and estimated flood damages for the urban centre of Can Tho city (Ninh Kieu district), containing the must-have features of a co-design tool (e.g. inbuilt input library, flexible options, easy to use, quick results, user-friendly interface). Inform provides rapid flood risk assessments with quantitative information (e.g. flood levels, flood hazard and damage maps, estimated damages) required for co-designing efforts aimed at flood risk reduction for Ninh Kieu district in the future.
Development of an Ultrafast Low-Energy Electron Diffraction Setup
by Max GuldeThis book presents an Ultrafast Low-Energy Electron Diffraction (ULEED) system that reveals ultrafast structural changes on the atomic scale. The achievable temporal resolution in the low-energy regime is improved by several orders of magnitude and has enabled the melting of a highly-sensitive, molecularly thin layer of a polymer crystal to be resolved for the first time. This new experimental approach permits time-resolved structural investigations of systems that were previously partially or totally inaccessible, including surfaces, interfaces and atomically thin films. It will be of fundamental importance for understanding the properties of nanomaterials so as to tailor their properties.