- Table View
- List View
Development Planning: A Strategic Approach to Future Air Force Capabilities
by Committee on Improving the Effectiveness Efficiency of U.S. Air Force Pre-Acquisition Development PlanningThe development and application of technology has been an essential part of U. S. airpower, leading to a century of air supremacy. But that developmental path has rarely been straight, and it has never been smooth. Only the extraordinary efforts of exceptional leadership - in the Air Forces and the wider Department of Defense, in science and in industry - have made the triumphs of military airpower possible. "Development Planning" provides recommendations to improve development planning for near-term acquisition projects, concepts not quite ready for acquisition, corporate strategic plans, and training of acquisition personnel. This report reviews past uses of development planning by the Air Force, and offers an organizational construct that will help the Air Force across its core functions. Developmental planning, used properly by experienced practitioners, can provide the Air Force leadership with a tool to answer the critical question, Over the next 20 years in 5-year increments, what capability gaps will the Air Force have that must be filled? Development planning will also provide for development of the workforce skills needed to think strategically and to defectively define and close the capability gap. This report describes what development planning could be and should be for the Air Force.
Development Practice in Eastern and Southern Africa: Lived Experiences from the Trenches
by Tshilidzi Madzivhandila Sepo Hachigonta Joseph Francis Joseph Kamuzhanje Oluwatoyin Dare Kolawole Shirley DeWolfThis book is a rare collection of reflective and reflexive stories that reveal how seasoned academics, agents of grassroots social change, leaders and journalists transformed and shaped the development landscape in eastern and southern Africa. Whereas practical experiences are crucial assets and resources for shaping the academic environment and development practice landscape, most of the existing literature recommended as key learning materials in tertiary institutions is rarely in synch with the practical realities of development practice. The shared individual lived experiences from academic endeavours and fieldwork provide hands-on tools for students and emerging practitioners who might be involved in or are currently facilitating development work. The thrust of the book, therefore, is to demystify the day-to-day experiences of development practitioners while contributing to learning pathways or strategies for achieving viable solutions to the myriad of challenges, which grassroots communities face. The relevance of the book as a crucial resource for students pursuing development-oriented degree programmes in colleges and universities is obvious. Without any doubt, the compilation will be handy in the implementation of diverse development-oriented transformation agenda at academic, programming and policy levels.
Development, Regeneration and Plasticity of the Autonomic Nervous System
by I. A. Hendry C. E. HillEach volume in the Autonomic Nervous System series deals with a different area of autonomic control in health and disease. This, the second volume, provides an overview on the nature of the factors that exert constraints on the differentiation and maturation of the autonomic nervous system. Subjects covered include: development of autonomic neurones; molecules affecting nerve growth and survival; regeneration after injury; and the degree to which the wiring of the nervous system is rigid or fixed.
Development Strategies and Biodiversity: Darwinian Fitness and Evolution in the Anthropocene (Fascinating Life Sciences)
by David Costantini Valeria MarascoDevelopment is a complex and highly dynamic process involving the cross talk among genes, maternal effects and environmental circumstances. Widespread evidence from plant to animal species show that variation in developmental conditions can modulate life history trajectories and influence key traits, such as growth, reproduction, and senescence. These effects are not limited to a single generation but can also be passed on future generations. This book aims to bring together studies of early life effects from the fields of evolutionary biology, global change biology, and biomedicine to synthesise and improve current knowledge of the mechanisms involved, and how variation in early life conditions translates into Darwinian fitness outcomes. Relying on examples of organisms’ responses to the ongoing and future environmental challenges of the Anthropocene, this book takes a novel approach to address the adaptive meaning of early life effects. The book has a broad scientific approach, targeting eco-evolutionary biologists, behavioural biologists, eco-physiologists, eco-toxicologists, as well as epidemiologists and biomedical scientists.
Developmental and Reproductive Toxicology: A Practical Approach
by Ronald D. HoodCompletely revised and updated, Developmental and Reproductive Toxicology: A Practical Approach, Second Edition draws together valuable information typically scattered throughout the literature, plus some not previously published, into one complete resource. In addition to the traditional aspects of developmental toxicity testing, the book covers e
Developmental Approaches to Human Evolution
by Julie Boughner Campbell RolianDevelopmental Approaches to Human Evolution encapsulates the current state of evolutionary developmental anthropology. This emerging scientific field applies tools and approaches from modern developmental biology to understand the role of genetic and developmental processes in driving morphological and cognitive evolution in humans, non-human primates and in the laboratory organisms used to model these changes. Featuring contributions from well-established pioneers and emerging leaders, this volume is designed to build research momentum and catalyze future innovation in this burgeoning field. The book's broad research scope encompasses soft and hard tissues of the head and body, including the skeleton, special senses and the brain. Developmental Approaches to Human Evolution is an invaluable resource on the mechanisms of primate and vertebrate evolution for scholars across a wide array of intersecting disciplines, including primatology, paleoanthropology, vertebrate morphology, evolutionary developmental biology and health sciences.
Developmental Behavioral Neuroscience: The Minnesota Symposia on Child Psychology, Volume 24 (Minnesota Symposia on Child Psychology Series #Vol. 24)
by Megan R. Gunnar Charles A. NelsonThis volume provides an introduction to current research on the relation between brain development and the development of cognitive, linguistic, motor, and emotional behavior. At least two audiences will benefit from this book: psychologists interested in brain development, and neuroscientists interested in behavioral development. Although each chapter is content-oriented, the volume as a whole provides a well integrated summary of the latest findings from developmental behavioral neuroscience.
Developmental Biology
by Scott F. Gilbert Michael J. F. BarresiA classic gets a new coauthor and a new approach: Developmental Biology, Eleventh Edition, keeps the excellent writing, accuracy, and enthusiasm of the Gilbert Developmental Biology book, streamlines it, adds innovative electronic supplements, and creates a new textbook for those teaching Developmental Biology to a new generation. Several new modes of teaching are employed in the new Gilbert and Barresi textbook. The videos explaining development--as well as those from Mary Tyler's Vade Mecum--are referenced throughout the book, and several other valuable new elements have been added.
Developmental Biology and Cancer
by Gisele M. Hodges Charles RowlattThis book addresses possible analogies between cancer and developmental biology. An international group of experts provides a multidisciplinary approach, allowing biological or clinical scientists involved with cancer research to integrate specific information from diverse areas.Five concepts of cancer are presented, and developmental biology is reviewed at five levels. These are integrated in discussions of failure in organisation as a basis of cancer and its control. The book will be a valuable reference for both newcomers as well as experienced biological and clinical scientists.
Developmental Biology in Prokaryotes and Lower Eukaryotes
by Tomás González Villa Trinidad de Miguel Bouzas‘Developmental biology’ is widely understood as processes, which mainly concern embryonic animal development and differentiation of cells and tissue. It is also often defined as the timeline for the evolutionary developmental biology of eukaryotic multicellular higher organisms, i.e., plants and animals. The development of prokaryotes and lower eukaryotes in contrary has been neglected for a long time, which was the motivation for publishing this book. This book highlights one of Darwin's most important findings: Evolution is a creative, but not a conscious process. It also illustrates that this concept does not only apply to multicellular higher organisms, but affects every form of life.The reader shall find complex biochemical and genetic pathways of bacteria, yeasts or protozoa, comparable to those exhibited by plants or animals. The molecular mechanisms of dramatic genome rearrangements, recombination and horizontal gene transfer that are responsible for evolutionary adaptations are discussed. Additionally, the book covers bacteria of the genera Myxobacteriales and Caulobacterales, which are able to develop tissue-like cellular organization. The morphogenesis of entomopathogenic fungi and the endosymbiont theory are also addressed. The book is a useful introduction to the field for junior scientists, interested in bacteriology, protistology and fungal development. It is also an interesting read for advanced scientists, giving them a broader view of the field beyond their area of specialization.
Developmental Biology of Peripheral Lymphoid Organs
by Peter BaloghThe human immune system is a complex network of tissues and organs dispersed throughout the body. Immunology, as one of the most rapidly evolving fields in bio¬medical research, has to date covered the essential cellular and molecular events neces¬sary for immune responses to occur. However, it has paid relatively little attention to important developmental processes underlying the formation of the tissues themselves that carry out immune responses in humans and other mammalians. In contrast to the thymus and bone marrow that are the sole tissues for generating mature leukocytes for antigen recognition and han¬dling in humans and most mammalian species, the peripheral lymphoid tissues where adaptive immune responses are focused display broad tissue distribution and possess diverse archi¬tectural characteristics. These organs develop prior to the individual's exposure to external antigens, and despite their similar functions, their varied appearances indicate a substantial complexity of tissue ontogeny. This volume presents a comprehensive overview of the developmental features of the major peripheral lymphoid organs, thus examining the connection between immunological functionality and structural characteristics utilizing a developmental approach, for an audience ranging from undergraduate students to senior researchers in immunology, histology and clinical medicine.
Developmental Biology of the Sea Urchin and Other Marine Invertebrates
by David J. Carroll Stephen A. StrickerIn Developmental Biology of the Sea Urchin and Other Marine Invertebrates: Methods and Protocols, expert researchers in the field detail many of the methods which are now used to study sea urchins and other marine invertebrates in the laboratory. These include methods and protocols on imaging, other useful experimental tools for cell, developmental biology research, variety of molecular biological methods, and strategies for utilizing the sea urchin genome. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Developmental Biology of the Sea Urchin and other Marine Invertebrates: Methods and Protocols seeks to aid scientists in the further study into sea urchins and other marine invertebrates.
Developmental Biology of the Sea Urchin and Other Marine Invertebrates: Methods and Protocols (Methods in Molecular Biology #2219)
by David J. Carroll Stephen A. StrickerThis detailed second edition presents a wide variety of marine invertebrate model systems, from cephalochordata to holothurians, along with novel experimental protocols for taking advantage of their unique properties. The techniques range from culturing the organisms to modifying their DNA. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Developmental Biology of the Sea Urchin and Other Marine Invertebrates: Methods and Protocols, Second Edition is an ideal guide for researchers working with these versatile organisms and for furthering our understanding of fundamental biological questions.
Developmental Biology Protocols, Volume I
by Rocky S. Tuan Cecilia W. LoDrawing on state-of-the-art cellular and molecular techniques as well as new and sophisticated imaging and information technologies, this comprehensive, three-volume collection of cutting-edge protocols provides readily reproducible methods for studying and analyzing the events of embryonic development. Volume 1 (ISBN: 089603-574-3) contains techniques for establishing and characterizing several widely used experimental model systems, for the study of developmental patterns and morphogenesis, and for the examination of embryo structure and function. There are also step-by-step methods for the analaysis of cell lineage, the production and use of chimeras, and the experimental and molecular manipulation of embryos, including the application of viral vectors. Volume 2 (ISBN: 0-89603-575-1) describes state-of-the-art methods for the study of organogenesis, the analysis of abnormal development and teratology, the screening and mapping of novel genes and mutations, and the application of transgenesis, including the production of transgenic animals and gene knockouts. No less innovative, volume 3 (ISBN: 0-89603-576-X) introduces powerful techniques for the manipulation of developmental gene expression and function, the analysis of gene expression, the characterization of tissue morphogenesis and development, the in vitro study of differentiation and development, and the genetic analysis of developmental models of diseases. Highly practical and richly annotated, the three volumes of Developmental Biology Protocols describe multiple experimental systems and details techniques adopted from the broadest array of biomedical disciplines.
Developmental Biology Protocols, Volume II
by Rocky S. Tuan Cecilia W. LoDrawing on state-of-the-art cellular and molecular techniques as well as new and sophisticated imaging and information technologies, this comprehensive, three-volume collection of cutting-edge protocols provides readily reproducible methods for studying and analyzing the events of embryonic development. Volume 1 (ISBN: 089603-574-3) contains techniques for establishing and characterizing several widely used experimental model systems, for the study of developmental patterns and morphogenesis, and for the examination of embryo structure and function. There are also step-by-step methods for the analaysis of cell lineage, the production and use of chimeras, and the experimental and molecular manipulation of embryos, including the application of viral vectors. Volume 2 (ISBN: 0-89603-575-1) describes state-of-the-art methods for the study of organogenesis, the analysis of abnormal development and teratology, the screening and mapping of novel genes and mutations, and the application of transgenesis, including the production of transgenic animals and gene knockouts. No less innovative, volume 3 (ISBN: 0-89603-576-X) introduces powerful techniques for the manipulation of developmental gene expression and function, the analysis of gene expression, the characterization of tissue morphogenesis and development, the in vitro study of differentiation and development, and the genetic analysis of developmental models of diseases. Highly practical and richly annotated, the three volumes of Developmental Biology Protocols describe multiple experimental systems and details techniques adopted from the broadest array of biomedical disciplines.
Developmental Biology Protocols, Volume III
by Cecilia W. Lo Rocky S. TuanDrawing on state-of-the-art cellular and molecular techniques as well as new and sophisticated imaging and information technologies, this comprehensive, three-volume collection of cutting-edge protocols provides readily reproducible methods for studying and analyzing the events of embryonic development. Volume 1 (ISBN: 089603-574-3) contains techniques for establishing and characterizing several widely used experimental model systems, for the study of developmental patterns and morphogenesis, and for the examination of embryo structure and function. There are also step-by-step methods for the analaysis of cell lineage, the production and use of chimeras, and the experimental and molecular manipulation of embryos, including the application of viral vectors. Volume 2 (ISBN: 0-89603-575-1) describes state-of-the-art methods for the study of organogenesis, the analysis of abnormal development and teratology, the screening and mapping of novel genes and mutations, and the application of transgenesis, including the production of transgenic animals and gene knockouts. No less innovative, volume 3 (ISBN: 0-89603-576-X) introduces powerful techniques for the manipulation of developmental gene expression and function, the analysis of gene expression, the characterization of tissue morphogenesis and development, the in vitro study of differentiation and development, and the genetic analysis of developmental models of diseases. Highly practical and richly annotated, the three volumes of Developmental Biology Protocols describe multiple experimental systems and details techniques adopted from the broadest array of biomedical disciplines.
Developmental Disorders of the Brain: Neuropsychological, Neuropsychiatric And Evolutionary Perspectives (Brain, Behaviour and Cognition)
by Nicole J. Rinehart John L. Bradshaw Peter G. EnticottDevelopmental Disorders of the Brain: Brain and Behaviour addresses disabilities that occur or have their roots in the early, developmental phase of life which are of utmost concern to parents, siblings, carers and teachers. This text describes the latest clinical and behavioral findings of disorders which largely or entirely involve the frontostriatal (basal ganglia) system including Tourette's, Obsessive-Compulsive and Attention-Deficit-Hyperactivity disorders, Schizophrenia, Autism, gambling and addiction, depression, and Conduct, Developmental Motor Co-ordination, and language disorders. Examples of disorders involving the frontocerebellar are also described such as Asperger's disorder, Williams, Fragile X, and Cerebellar Cognitive Affective syndromes, and Friedreich Ataxia. This book also discusses the relevant anatomy, physiology and pathology, and some of the major functions mediated by affected or relevant structures, together with accounts of the latest recording, brain imaging and stimulating techniques related to these kinds of disorders. Covering both frontostriatal and frontocerebellar, systems which control and direct normal behavior, and which can fail with often distressing consequences during development, as well as addressing behavioural, clinical, pathophysiological and technical aspects, this text is vital to understanding, diagnosis and management of developmental disorders of the brain. This text will be of great interest to clinicians, researchers, teachers and parents.
Developmental Dysplasia of the Hip: From Early Sonographic Diagnosis to Effective Treatment
by Joseph O’Beirne Konstantinos ChlapoutakisThis book is a reference source containing all the relevant information about Developmental Dysplasia of the Hip (DDH), for people who practice or utilize hip sonography for the early detection and treatment of DDH. It aims at improving the population screening for DDH, thus contributing to the elimination of the disorder and its devastating consequences. What makes this book different from existing literature is the fact that, apart from the (updated) information about the disorder (including development, pathophysiology, etiology, pathogenesis, risk factors etc.) and a short technical guidance, the reader will find all relevant knowledge to organize training and set up screening. This includes analysis of the rationale behind universal sonographic screening, a comparative presentation of the sonographic techniques, teaching course structure / management and setting up a screening service, including audit, quality control of the scans etc. Special chapters about radiological diagnosis, imaging the consequences of non-diagnosis or maltreatment of the disorder, clinical management of DDH cases and shaping the future of hip sonography, are also provided. The book will be of interest to any medical doctor, but in particular to those working in the fields of radiology, pediatrics, orthopedics or general medicine, sonographers performing hip scans, or specialist nurses dealing with DDH.
Developmental Genetics and Plant Evolution (Systematics Association Special Volumes)
by Quentin C. B. Cronk Richard M. Bateman Julie A. HawkinsA benchmark text, Developmental Genetics and Plant Evolution integrates the recent revolution in the molecular-developmental genetics of plants with mainstream evolutionary thought. It reflects the increasing cooperation between strongly genomics-influenced researchers, with their strong grasp of technology, and evolutionary morphogenetists and sys
Developmental Genomics of Ascidians
by Noriyuki SatohThe simplicity and lack of redundancy in their regulatory genes have made ascidians one of the most useful species in studying developmental genomics. In Developmental Genomics of Ascidians, Dr. Noriyuki Satoh explains the developmental genomics of ascidians, stresses the simplicity of Ciona developmental system, and emphasizes single-cell level analyses. This book actively accentuates the advantages of using ascidians as model organisms in an up-and-coming field of developmental genomics.
Developmental Neurobiology
by Lynne BianchiDevelopmental Neurobiology tells the extraordinary process of neural development by showing how the scientific discoveries were made and how the hypotheses evolved over time. Each chapter explores the specific mechanisms of development while highlighting the key experiments and methods used to make those discoveries—including descriptions of, and experiments utilizing, both invertebrate and vertebrate animal models. This distinctive approach provides the essential facts while strengthening the reader’s appreciation of the scientific method. Discussions of neurodevelopmental disorders and therapeutic approaches to them will captivate those interested in the more clinical aspects of the field. With its clear illustrations and easy-to-follow writing style, Developmental Neurobiology presents an accessible approach to neural development for undergraduate students.
Developmental Neuropsychology: A Clinical Approach
by Vicki Anderson Elisabeth Northam Jacquie WrennallThis book addresses key issues in child neuropsychology but differs from other books in the field in its emphasis on clinical practice rather than research issues. Although research findings are presented, they are described with emphasis on what is relevant for assessment, treatment and management of pediatric conditions. The authors have chosen to focus on a number of areas. First, the text examines the natural history of childhood CNS insult, highlighting studies where children have been followed over time to determine the impact of injury on ongoing development. Second, processes of normal and abnormal cerebral and cognitive development are outlined and the concepts of brain plasticity and the impact of early CNS insult discussed. Finally, using a number of common childhood CNS disorders as examples, the authors develop a model which describes the complex interaction among biological, psychosocial and cognitive factors in the brain injured child.The text will be of use on advanced undergraduate courses in developmental neuropsychology, postgraduate clinical training programmes, and for professionals working with children in clinical psychology, clinical neuropsychology, and in educational and rehabilitation contexts.
Developmental Neuropsychology: A Clinical Approach (Brain, Behaviour and Cognition)
by Vicki Anderson Elisabeth Northam Jacquie WrennallThis fully updated edition of Developmental Neuropsychology: A Clinical Approach addresses key issues in child neuropsychology with a unique emphasis on evidence-informed clinical practice rather than research issues. Although research findings are presented, they are described with emphasis on what is relevant for assessment, treatment and management of paediatric conditions. The authors focus on a number of areas. First, the text examines the natural history of childhood central nervous system (CNS) insult, highlighting studies where children have been followed over time to determine the impact of injury on ongoing development. Second, processes of normal and abnormal cerebral and cognitive development are outlined and the concepts of brain plasticity and the impact of early CNS insult discussed. Third, using a number of common childhood CNS disorders as examples, the authors develop a model which describes the complex interaction among biological, psychosocial and cognitive factors in the brain-injured child. Finally, principles of evidence-based assessment, diagnosis and intervention are discussed. The text will be of use on advanced undergraduate courses in developmental neuropsychology, postgraduate clinical training programmes and for professionals working with children in clinical psychology, clinical neuropsychology and educational and rehabilitation contexts. The text is also an important reference for those working in paediatric research.
Developmental Neurotoxicology Research: Principles, Models, Techniques, Strategies, and Mechanisms
by Cheng Wang William Slikker Jr.This book describes how systems biology, pharmacogenomic and behavioral approaches, as applied to neurodevelopmental toxicology, provide a structure to arrange information in a biological model. Authors review and discuss approaches that can be used as effective tools to dissect mechanisms underlying pharmacological and toxicological phenomena associated with the exposure to drugs or environmental toxicants during development. This book presents cross-cutting research tools and animal models, along with applications to the studies associated with potential anesthetic-induced developmental neurotoxicity; the developmental basis of adolescent or adult onset of disease; risk assessment of methyl mercury and its effects on neurodevelopment; challenges in the field to identify environmental factors of relevance to autism; and the strategy and progress of epilepsy research.
Developmental Origins of Health and Disease: From Biological Basis to Clinical Significance (Advances in Experimental Medicine and Biology #1012)
by Takeo Kubota Hideoki FukuokaThis book addresses the developmental origins of health and disease (DOHaD), a new medical concept that demonstrates that various adult diseases start in the fetal period. It discusses our current understanding of the molecular mechanisms of DOHaD, including gene body epigenetics and non-coding RNA, and comprehensively examines diseases such type 2 diabetes, a well known as standard DOHaD-associated disease, as well as non-alcoholic fatty liver disease, hypertension and neurodevelopmental disorders. It argues that most adult diseases start at a very early stage, such as in the fetal and neonatal periods, and that earlier prevention and intervention would result in better outcomes for adult diseases such as type 2 diabetes and cardiac disorders, which are increasing in both developed and developing countries. The book appeals to obstetricians and pediatricians, as well as physicians who treat adult patients, wanting to understand the origins of diseases.