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Don't Unplug: How Technology Saved My Life and Can Save Yours Too
by Chris DancyChris Dancy, the world's most connected person, inspires readers with practical advice to live a happier and healthier life using technologyIn 2002, Chris Dancy was overweight, unemployed, and addicted to technology. He chain-smoked cigarettes, popped pills, and was angry and depressed. But when he discovered that his mother kept a record of almost every detail of his childhood, an idea began to form. Could knowing the status of every aspect of his body and how his lifestyle affected his health help him learn to take care of himself? By harnessing the story of his life, could he learn to harness his own bad habits? With a little tech know-how combined with a healthy dose of reality, every app, sensor, and data point in Dancy's life was turned upside down and examined. Now he's sharing what he knows. That knowledge includes the fact that changing the color of his credit card helps him to use it less often, and that nostalgia is a trigger for gratitude for him. A modern-day story of rebirth and redemption, Chris' wisdom and insight will show readers how to improve their lives by paying attention to the relationship between how we move, what we eat, who we spend time with, and how it all makes us feel. But Chris has done all the hard work: Don't Unplug shows us how we too can transform our lives.
Doom with a View: Historical and Cultural Contexts of the Rocky Flats Nuclear Weapons Plant
by Kristen IversenTucked up against the Rocky Mountains, just west of Denver, sits the remnants of one of the most notorious nuclear weapons sites in North America: Rocky Flats. With a history of environmental catastrophes, political neglect, and community-wide health crises, this site represents both one of the darkest and most controversial chapters in our nation's history, and also a conundrum on repurposing lands once considered lost. As the crush of encroaching residential areas close in on this site and the generation of Rocky Flats workers passes on, the memory of Rocky Flats is receding from the public mind; yet the need to responsibly manage the site, and understand the consequences of forty years of plutonium production and contamination, must be a part of every decision for the land's future.
The Doomsday Calculation: How an Equation that Predicts the Future Is Transforming Everything We Know About Life and the Universe
by William PoundstoneFrom the author of Are You Smart Enough to Work at Google?, a fascinating look at how an equation that foretells the future is transforming everything we know about life, business, and the universe.In the 18th century, the British minister and mathematician Thomas Bayes devised a theorem that allowed him to assign probabilities to events that had never happened before. It languished in obscurity for centuries until computers came along and made it easy to crunch the numbers. Now, as the foundation of big data, Bayes' formula has become a linchpin of the digital economy.But here's where things get really interesting: Bayes' theorem can also be used to lay odds on the existence of extraterrestrial intelligence; on whether we live in a Matrix-like counterfeit of reality; on the "many worlds" interpretation of quantum theory being correct; and on the biggest question of all: how long will humanity survive?The Doomsday Calculation tells how Silicon Valley's profitable formula became a controversial pivot of contemporary thought. Drawing on interviews with thought leaders around the globe, it's the story of a group of intellectual mavericks who are challenging what we thought we knew about our place in the universe. The Doomsday Calculation is compelling reading for anyone interested in our culture and its future.
The Doomsday Handbook
by Alok JhaWe live in a world positively teeming with threats and apocalyptic scenarios. Many of them are familiar: terrorism, deadly viruses, global warming and war, but many others most of us can't even imagine: self-replicating nanobots that can devour an entire planet, high-energy experiments that threaten to suck the Earth into a mini black hole, and even super-sophisticated scientific contraptions that can put an end to the entire universe.
The Doomsday Lobby
by James T. BennettFederal patronage of science was never contemplated by the framers of the Constitution, but they did seek to "promote the Progress of Science and useful Art" by granting inventors patent rights. However, direct subvention to scientists and scientific organizations was not considered appropriate activity of the central government. In the 19th Century, American science was funded almost entirely through private investors. Since WWII, however, the federal government has become the primary patron of American science. From the race-to-space in the 1950s to current furor over global warming, Bennett traces the subtle and not-so-subtle ways in which government has co-opted scientific research and reinforced a culture in which challengers to proscribed wisdom are frozen out. Citing original documents and media reports, Bennett offers a compelling, entertaining, and thought-provoking perspective on political influence on scientific research and its implications for a democratic society. "During the Nineteenth Century, almost entirely on private funding, American science grew from practically nothing to world class. Now, however, over fifty percent of American science is funded by the federal government. Dr. Bennett traces the path, "crisis" after "crisis," by which American science became practically an arm of the federal government. His tale is a cautionary one, warning against future "crisis mongers" who would extend the government's already majority control of American science even further. His warning is a timely one, and it should be heeded." Joseph P. Martino, author of Science Funding: Politics and Porkbarrel "Bennett's latest book offers a challenging interpretation of the rise of the American federal science establishment since World War II. Focusing primarily on the growth of the space program, Bennett argues that crisis, real or imagined, is the source of state power and state funding for science. The Doomsday Lobby offers what no doubt will be viewed as a controversial contribution to the history of American science policy, and more broadly to an understanding of the role of the state in society." James D. Savage, Professor of Politics, University of Virginia, and author of Funding Science in America
The Doomsday Machine: The High Price of Nuclear Energy, the World's Most Dangerous Fuel
by Martin Cohen Andrew McKillopToday, there are over one hundred nuclear reactors operating in our backyards, from Indian Point in New York to Diablo Canyon in California. Proponents claim that nuclear power is the only viable alternative to fossil fuels, and due to rising energy consumption and the looming threat of global warming, they are pushing for an even greater investment. Here, energy economist Andrew McKillop and social scientist Martin Cohen argue that the nuclear power dream being sold to us is pure fantasy. Debunking the multilayered myth that nuclear energy is cheap, clean, and safe, they demonstrate how landscapes are ravaged in search of the elusive yellowcake to fuel the reactors, and how energy companies and politicians rarely discuss the true costs of nuclear power plants - from the subsidies that build the infrastructure to the unspoken guarantee that the public will pick up the cleanup cost in the event of a meltdown, which can easily top $100 billion dollars.
The Doomsday Vault (Everwhen School of Time Travel (and Other Odd Sciences))
by Thomas WheelerFrom the screenwriter of Academy Award–nominated Puss in Boots and Puss in Boots: The Last Wish comes an inventive middle grade adventure about an interdimensional school for time travelers perfect for fans of the Spy School and Mr. Lemoncello&’s Library series.When Bertie Wells accidentally creates a black hole in his bedroom in the year 1878, the last thing he expects is for a grown-up to step out. Darla Marconi comes with an offer: Bertie is invited to attend the EverWhen School of Time Travel and Other Odd Sciences. Not exactly thrilled at the idea, but not exactly having anything better to do, Bertie agrees. And that was only the first weird thing to happen to him that day. Thankfully, he's not alone—144 years in the future, math whiz Zoe Fuentes just accepted the same invitation, and 550 years in the past, Amelia da Vinci (yes, that da Vinci) has also decided to attend. Transported to 2024 for their first semester of school, these three must team up and work together in order to survive the year, including weathering a time paradox, solving the case of a disappearing dean, and uncovering the truth behind a shady intergalactic secret society. At least time is on their side!
Dopamine: Endocrine and Oncogenic Functions
by Nira Ben-JonathanDopamine is a small molecule traditionally regarded as a brain-derived neuronal modulator implicated in many neurological and psychiatric disorders. Outside the brain, dopamine fulfills all the criteria of a circulating hormone which affects normal and abnormal functions of multiple organs and regulatory systems and is also involved in many aspects of cancer formation and progression. This book provides a much needed systematic account of dopamine as an endocrine and autocrine/paracrine hormone and fills a major gap in the overall understanding of the production, distribution and actions of this very important molecule. Key Features: Explores the many different faces of dopamine as autocrine, paracrine and endocrine molecule Documents the adverse effects of antipsychotics on dopamine functions Reviews the many ways dopamine affects the cardiovascular, renal and reproductive systems Provides updates on receptor oligomerization and signaling Examines the role of dopamine in tumorigenesis Related Titles Jones, S. ed. Dopamine - Glutamate Interactions in the Basal Ganglia (ISBN 978-0-3673-8197-4) Luo, L. Principles of Neurobiology (ISBN 978-0-8153-4494-0) Sidhu, A. et al., eds. Dopamine Receptors and Transporters (ISBN 978-0-8247-0854-2)
Dopamine
by Nadine KabbaniDopamine, a catecholamine transmitter, plays a number of vital physiological roles in the brain and body, and, in recent years, studies on the role of dopamine in disease have opened new avenues of research and discovery. In Dopamine: Methods and Protocols, experts and key figures within the field provide detailed protocols on leading approaches in the study of dopamine within biological systems. Divided into sections on cellular/biochemical, imaging, genetics, and electrophysiology, this collections includes protocols for bioluminescence and fluorescence imaging, receptor immunoprecipitation and proteomic analysis, creation and characterization of a mouse model of Parkinson's disease, real time measurement of dopamine in the brain, and modeling signal transduction in silico. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective subjects, lists of materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and convenient, Dopamine: Methods and Protocols serves as an ideal guide for students and experts alike, as well as for anyone interested in exploring the vast and crucial field of dopamine research.
Dopamine and Sleep
by Jaime M. Monti S. R. Pandi-Perumal S. ChokrovertyThis book offers a comprehensive but highly readable compilation of papers on the role of dopamine in sleep and sleep disorders. Leading experts in sleep medicine, psychiatry and neuroendocrinology provide a broad perspective on the field, from established theories to the latest research advances. Accordingly, it represents an interdisciplinary, cutting-edge guide for sleep disorder specialists, sleep researchers, psychiatrists, neurologists, pulmonologists, psychologists, and behavioral sleep medicine specialists.
Dopamine - Glutamate Interactions in the Basal Ganglia
by Susan JonesThe basal ganglia are involved in complex brain functions, from voluntary movement control to learning and reward processing, and they are implicated in numerous neurological and psychiatric disorders. Information from the cerebral cortex and thalamus is conveyed to basal ganglia nuclei via glutamate release, while dopamine from the midbrain is rel
Dopamine in the Gut
by Jin-Xia ZhuDopamine is widely present in the central and peripheral nervous systems, as well as in non-nervous systems. Parkinson's disease is well recognized as a dopaminergic neurodegenerative disorder, and affected patients often show early signs of gastrointestinal disorders at initial stages of the disease. Apart from the changes that occur in emotion, movement behaviors, learning and memory, metabolism etc., dopamine has also been demonstrated to play very crucial roles in the functional regulation of peripheral organs such as the heart, blood vessels, kidneys, and gut. Most recently, dopamine function in the gut has received enormous attention. Not only does dopamine regulate gut motility, ion transport, and mucosal barrier, but it is becoming more pertinent that more than 60% of dopamine in the body stems from the gut, which has not yet been properly addressed and substantially explored. Therefore, this book will discuss the brain-gut axis by providing novel and significant insight into the essence of gut-derived dopamine in mammals. It aims to inspire further research on dopaminergic regulation of gut function and disease genesis.
Dopamine Nation: Finding Balance in the Age of Indulgence
by Dr Anna LembkeAll around us people are looking at their phones too much, eating too much, drinking too much. Our world is addicted to fleeting distracting pleasures that get us nowhere. Dr Anna Lembke provides a clear way back to a balanced life.This audiobook is about pleasure. It's also about pain. Most importantly, it's about how to find the delicate balance between the two, and why now more than ever finding balance is essential. We're living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting... The increased numbers, variety, and potency is staggering. The smartphone is the modern-day hypodermic needle, delivering digital dopamine 24/7 for a wired generation. As such we've all become vulnerable to compulsive overconsumption.In Dopamine Nation, Dr. Anna Lembke, psychiatrist and author, explores the exciting new scientific discoveries that explain why the relentless pursuit of pleasure leads to pain...and what to do about it. Condensing complex neuroscience into easy-to-understand metaphors, Lembke illustrates how finding contentment and connectedness means keeping dopamine in check. The lived experiences of her patients are the gripping fabric of her narrative. Their riveting stories of suffering and redemption give us all hope for managing our consumption and transforming our lives. In essence, Dopamine Nation shows that the secret to finding balance is combining the science of desire with the wisdom of recovery.'Dr Anna Lembke is a whiz on why we get hooked on things - and how we can enjoy pleasurable things in healthier doses.' - The Guardian(P) 2021 Penguin Random House Audio
Dopamine Nation: Finding Balance in the Age of Indulgence
by Dr. Anna LembkeINSTANT NEW YORK TIMES and LOS ANGELES TIMES BESTSELLER&“Brilliant . . . riveting, scary, cogent, and cleverly argued.&”—Beth Macy, author of Dopesick,as heard on Fresh AirThis book is about pleasure. It&’s also about pain. Most important, it&’s about how to find the delicate balance between the two, and why now more than ever finding balance is essential. We&’re living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting . . . The increased numbers, variety, and potency is staggering. The smartphone is the modern-day hypodermic needle, delivering digital dopamine 24/7 for a wired generation. As such we&’ve all become vulnerable to compulsive overconsumption. In Dopamine Nation, Dr. Anna Lembke, psychiatrist and author, explores the exciting new scientific discoveries that explain why the relentless pursuit of pleasure leads to pain . . . and what to do about it. Condensing complex neuroscience into easy-to-understand metaphors, Lembke illustrates how finding contentment and connectedness means keeping dopamine in check. The lived experiences of her patients are the gripping fabric of her narrative. Their riveting stories of suffering and redemption give us all hope for managing our consumption and transforming our lives. In essence, Dopamine Nation shows that the secret to finding balance is combining the science of desire with the wisdom of recovery.
Dopamine Nation: Finding Balance in the Age of Indulgence
by Dr Anna Lembke'Her stories have the power to transform your life' Lori Gottlieb, bestselling author of Maybe You Should Talk to Someone 'Radically changes the way we think about mental illness, pleasure, pain, reward and stress' Daniel Levitin, bestselling author of The Organized MindTHE NEW YORK TIMES AND SUNDAY TIMES BESTSELLER We are a wired generation. In these fast-paced times we are constantly bombarded by high-reward, high-dopamine stimuli. From texting to social media, food to drugs, gambling to shopping, we have become addicted to fleeting and distracting pleasures that are making us sick.In Dopamine Nation, psychiatrist and bestselling author Dr Anna Lembke reveals why our relentless pursuit of pleasure leads to pain and what we can do about it. Bringing together cutting-edge neuroscience with the gripping real life experiences from her clinical practice, Lembke explores how contentment and connectedness are essential tools in keeping dopamine in check. This is an essential book for anyone wanting to find a balance for a happier life.
Dopamine Receptor Technologies
by Mario TiberiTo foster a better understanding of dopamine receptor functionality, this detailed volume creates an interface between updated classical methods and new emerging technologies heretofore not available to new or seasoned researchers. Divided in five sections dedicated to experimental approaches investigating different facets of dopaminergic signal transduction, Dopamine Receptor Technologies covers epigenetic and post-transcriptional analysis, computational and biochemical techniques, visualization and imaging methods, molecular and cell biological tools, as well as behavioral assessment. The book, as a part of the popular Neuromethods series, provides insightful step-by-step protocols and methodological reviews that readers will find useful. Practical and versatile, Dopamine Receptor Technologies seeks to aid researchers in developing new pharmacological tools to improve our knowledge of in vivo roles played by each receptor subtype and the synthesis of prospective lead compounds for drug discovery.
The Dopamine Receptors
by Kim NeveAs sites of action for drugs used to treat schizophrenia and Parkinson's disease, dopamine receptors are among the most validated drug targets for neuropsychiatric disorders. Dopamine receptors are also drug targets or potential targets for other disorders such as substance abuse, depression, Tourette's syndrome, and attention deficit hyperactivity disorder. Updated from the successful first edition, "The Dopamine Receptors" serves as a reference work on dopamine receptors while also highlighting the areas of research that are most active today. To achieve this goal, authors have written chapters that set a broad area of research in its historical context, rather than focusing on the research output of their own laboratories.
Dopamine Receptors and Transporters: Function, Imaging and Clinical Implication, Second Edition
by Anita Sidhu Marc Laruelle Philippe Vernier"Details the function, characterization, and physiology of various dopamine receptor/transporter systems and explores their role in etiology, diagnosis, and disease management."
Dopants and Defects in Semiconductors
by Matthew D. McCluskey Eugene E. HallerPraise for the First Edition "The book goes beyond the usual textbook in that it provides more specific examples of real-world defect physics … an easy reading, broad introductory overview of the field" ―Materials Today "… well written, with clear, lucid explanations …"―Chemistry World This revised edition provides the most complete, up-to-date coverage of the fundamental knowledge of semiconductors, including a new chapter that expands on the latest technology and applications of semiconductors. In addition to inclusion of additional chapter problems and worked examples, it provides more detail on solid-state lighting (LEDs and laser diodes). The authors have achieved a unified overview of dopants and defects, offering a solid foundation for experimental methods and the theory of defects in semiconductors. Matthew D. McCluskey is a professor in the Department of Physics and Astronomy and Materials Science Program at Washington State University (WSU), Pullman, Washington. He received a Physics Ph.D. from the University of California (UC), Berkeley. Eugene E. Haller is a professor emeritus at the University of California, Berkeley, and a member of the National Academy of Engineering. He received a Ph.D. in Solid State and Applied Physics from the University of Basel, Switzerland.
Doping in Conjugated Polymers (Polymer Science and Plastics Engineering)
by Pradip KarAn A-to-Z of doping including its definition, its importance, methods of measurement, advantages and disadvantages, properties and characteristics—and role in conjugated polymers The versatility of polymer materials is expanding because of the introduction of electro-active behavior into the characteristics of some of them. The most exciting development in this area is related to the discovery of intrinsically conductive polymers or conjugated polymers, which include such examples as polyacetylene, polyaniline, polypyrrole, and polythiophene as well as their derivatives. "Synmet" or "synthetic metal" conjugated polymers, with their metallic characteristics, including conductivity, are of special interest to researchers. An area of limitless potential and application, conjugated polymers have sparked enormous interest, beginning in 2000 when the Nobel Prize for the discovery and development of electrically conducting conjugated polymers was awarded to three scientists: Alan J. Heeger, Alan G. MacDiarmid, and Hideki Shirakawa. Conjugated polymers have a combination of properties—both metallic (conductivity) and polymeric; doping gives the conjugated polymer's semiconducting a wide range of conductivity, from insulating to low conducting. The doping process is a tested effective method for producing conducting polymers as semiconducting material, providing a substitute for inorganic semiconductors. Doping in Conjugated Polymers is the first book dedicated to the subject and offers a comprehensive A-to-Z overview. It details doping interaction, dopant types, doping techniques, and the influence of the dopant on applications. It explains how the performance of doped conjugated polymers is greatly influenced by the nature of the dopants and their level of distribution within the polymer, and shows how the electrochemical, mechanical, and optical properties of the doped conjugated polymers can be tailored by controlling the size and mobility of the dopants counter ions. The book also examines doping at the nanoscale, in particular, with carbon nanotubes. Readership The book will interest a broad range of researchers including chemists, electrochemists, biochemists, experimental and theoretical physicists, electronic and electrical engineers, polymer and materials scientists. It can also be used in both graduate and upper-level undergraduate courses on conjugated polymers and polymer technology.
Doping in Sports
by Peter Hemmersbach Detlef ThiemeDoping in sports and the fight against it has gained increasing attention in recent years. The pharmacological basis for a possible performance enhancement in competitive sport through the administration of prohibited substances and methods as well as the analytical disclosure of such practices are comprehensively covered in 21 contributions by outstanding and distinctive authors.
Doping of Carbon Nanotubes
by Sergey Bulyarskiy Alexandr SaurovThis book addresses the control of electronic properties of carbon nanotubes. It presents thermodynamic calculations of the formation of impurities and defects in the interaction of nanotubes with hydrogen, oxygen, nitrogen and boron, based on theoretical models of the formation of defects in carbon nanotubes. It is shown that doping and adsorption lead to changes in the electronic structure of the tubes as well as to the appearance of impurity states in the HOMO-LUMO gap. The book presents examples of specific calculations for doping of carbon nanotubes with oxygen, hydrogen, nitrogen and boron, together with numerous experimental results and a comparison with the author's thermodynamic calculations. Possible directions of the technological processes of optimization are pointed out, as well as the perspectives of p-n-transition creation with the help of carbon nanotube arrays. The results presented were derived from the physics of the processes and a theoretical model of the technological processes. Though a wealth of empirical information on doping nanotubes has been accumulated in the scientific literature, what is lacking is a theoretical model for their analysis. As such, the book develops a thermodynamic model of the self-organization of structural elements in multicomponent systems - including carbon nanotubes, clusters and precipitates in condensed matter - and subsequently adapts it to the doping of carbon nanotubes. This approach allows readers to gain a far deeper understanding of the processes of doping carbon nanotubes.
Doppler-Effekt und Rotverschiebung: Klassische Theorie und Einsteinsche Effekte (essentials)
by Helmut Günther Volker MüllerDer Doppler-Effekt ist die Frequenzänderung von Wellen bei einer Relativgeschwindigkeit von Sender und Empfänger. So wird die Sirene einer Feuerwehr bei einer Vorbeifahrt deutlich tiefer. Der klassische Doppler-Effekt erlaubt es, den Bewegungszustand des Trägermediums der Wellen zu bestimmen. Für Licht im Vakuum ist die relativistische Gangverzögerung einer bewegten Uhr zu berücksichtigen. Die Frequenzverschiebung hängt dann nur von der Relativgeschwindigkeit ab. Es gibt keinen Bewegungszustand des Vakuums. Der Leser wird in die Lichtausbreitung in Gravitationsfeldern eingeführt. Die Autoren demonstrieren, dass Licht von kompakten Quellen eine gravitative Rotverschiebung erfährt und dass um Schwarze Löcher eine unendliche Rotverschiebung zu beobachten ist. Der Leser erfährt, warum im Kosmos zusätzlich eine kosmologische Rotverschiebung auftritt.
Doppler Radar Physiological Sensing
by Byung-Kwon Park Olga Boric-Lubecke Victor M. Lubecke Aditya Singh Amy D. DroitcourPresents a comprehensive description of the theory and practical implementation of Doppler radar-based physiological monitoring This book includes an overview of current physiological monitoring techniques and explains the fundamental technology used in remote non-contact monitoring methods. Basic radio wave propagation and radar principles are introduced along with the fundamentals of physiological motion and measurement. Specific design and implementation considerations for physiological monitoring radar systems are then discussed in detail. The authors address current research and commercial development of Doppler radar based physiological monitoring for healthcare and other applications. Explains pros and cons of different Doppler radar architectures, including CW, FMCW, and pulsed Doppler radar Discusses nonlinear demodulation methods, explaining dc offset, dc information, center tracking, and demodulation enabled by dc cancellation Reviews advanced system architectures that address issues of dc offset, spectrum folding, motion interference, and range resolution Covers Doppler radar physiological measurements demonstrated to date, from basic cardiopulmonary rate extractions to more involved volume assessments Doppler Radar Physiological Sensing serves as a fundamental reference for radar, biomedical, and microwave engineers as well as healthcare professionals interested in remote physiological monitoring methods. Olga Boric-Lubecke, PhD, is a Professor of Electrical Engineering at the University of Hawaii at Manoa, and an IEEE Fellow. She is widely recognized as a pioneer and leader in microwave radar technologies for non-contact cardiopulmonary monitoring, and in the design of integrated circuits for biomedical applications. Victor M. Lubecke, PhD, is a Professor of Electrical Engineering at the University of Hawaii at Manoa. He is an emeritus IEEE Distinguished Microwave Lecturer and has over 25 years of experience in research and development of devices and methods for radio-based remote sensing systems. Amy Droitcour, PhD, has spent ten years developing radar-based vital signs measurement technology through her dissertation research and leading product development as CTO of Kai Medical. She currently serves as Senior Vice President of R&D at Wave 80 Biosciences. Byung-Kwon-Park, PhD, is a senior research engineer at the Mechatronics R&D Center in Korea. Aditya Singh, PhD, is currently a postdoctoral researcher at the University of Hawaii Neuroscience and MRI research Program.
Doppler Ultrasound in Obstetrics and Gynecology
by Dev Maulik Christoph C. LeesExpanded and updated edition highlighting current standards and breakthroughs in the technology of Doppler ultrasound Includes latest advances in 3D and color doppler and 4D fetal echocardiography Includes more than 500 illustrations, including more than 150 in color