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The End of Breast Cancer: A Virus and the Hope for a Vaccine
by Kathleen T.Can a mouse virus cause breast cancer in women? Answering that question has become Dr. Kathleen Ruddy's life’s work. The End of Breast Cancer is the landmark book that gives an extraordinary glimpse into the history of breast cancer research, and the findings that support the theory that the virus that causes breast cancer in mice, and has also been found in rats, cats, dogs, and monkeys plays a significant role in 40-94% of human breast cancer. Researchers contend that we are one step away from having final proof of this. Once we know the cause, then we can move forward to develop a preventative vaccine. The first and only breast cancer specialist to compile this encyclopedic research in one volume, Dr. Ruddy writes: “If there’s a virus that causes breast cancer, and a safe and effective vaccine that can prevent this disease, we need to know about it now, not in another 100 years.” The End of Cancer represents the culmination of Ruddy’s research findings and the breakthroughs that are happening every day to unravel the mystery. We may well witness in our lifetimes the eradication of breast cancer.
The End of Epidemics: The Looming Threat to Humanity and How to Stop It
by Dr Jonathan D. Quick Bronwyn Fryer"Dr. Quick’s urgent message makes one hope that this book will reach a huge audience and that its exhortations will be acted on everywhere." - Meredith Wadman, The Wall Street JournalA leading doctor offers answers on the one of the most urgent questions of our time: How do we prevent the next global pandemic?The 2014 Ebola epidemic in Liberia terrified the world—and revealed how unprepared we are for the next outbreak of an infectious disease. Somewhere in nature, a killer virus is boiling up in the bloodstream of a bird, bat, monkey, or pig, preparing to jump to a human being. This not-yet-detected germ has the potential to wipe out millions of lives over a matter of weeks or months. That risk makes the threat posed by ISIS, a ground war, a massive climate event, or even the dropping of a nuclear bomb on a major city pale in comparison. In The End of Epidemics, Harvard Medical School faculty member and Chair of the Global Health Council Dr. Jonathan D. Quick examines the eradication of smallpox and devastating effects of influenza, AIDS, SARS, and Ebola. Analyzing local and global efforts to contain these diseases and citing firsthand accounts of failure and success, Dr. Quick proposes a new set of actions which he has coined “The Power of Seven,” to end epidemics before they can begin. These actions include:- Spend prudently to prevent disease before an epidemic strikes, rather than spending too little, too late- Ensure prompt, open, and accurate communication between nations and aid agencies, instead of secrecy and territorial disputes- Fight disease and prevent panic with innovation and good science Practical and urgent, The End of Epidemics is crucial reading for citizens, health professionals, and policy makers alike.
The End of Everything: (Astrophysically Speaking)
by Katie MackFrom one of the most dynamic rising stars in astrophysics, an accessible and eye-opening look at five ways the universe could end, and the mind-blowing lessons each scenario reveals about the most important concepts in cosmology.We know the universe had a beginning. With the Big Bang, it expanded from a state of unimaginable density to an all-encompassing cosmic fireball to a simmering fluid of matter and energy, laying down the seeds for everything from black holes to one rocky planet orbiting a star near the edge of a spiral galaxy that happened to develop life as we know it. But what happens to the universe at the end of the story? And what does it mean for us now? Dr. Katie Mack has been contemplating these questions since she was a young student, when her astronomy professor informed her the universe could end at any moment, in an instant. This revelation set her on the path toward theoretical astrophysics. Now, with lively wit and humor, she takes us on a mind-bending tour through five of the cosmos&’s possible finales: the Big Crunch, Heat Death, the Big Rip, Vacuum Decay (the one that could happen at any moment!), and the Bounce. Guiding us through cutting-edge science and major concepts in quantum mechanics, cosmology, string theory, and much more, The End of Everything is a wildly fun, surprisingly upbeat ride to the farthest reaches of all that we know.
The End of Final Causes in Biology
by Lucas John MixThis book provides a straightforward introduction to teleology in biology, the work it did and the work it can do. Informed by history and philosophy, it focuses on scientific concerns. Seventeenth, eighteenth, and nineteenth century biologists proposed a menagerie of biological “actors” to explain power without appealing to Aristotelian vegetable souls and final causes. Three constraints on teleology narrowed the field, selecting among the various actors as they mutated and recombined. Methodological naturalism, local adaptation, and blind chance each represent a significant philosophical advance in biology. Kant, Darwin, and the Modern Synthesis provided a new teleology, grounded in natural selection, an etiological recursion of form and function, and the details of carbon chemistry on Earth. They naturalized teleology, but they also finalized nature, shifting conceptions about the world and science. Understanding these links – historical, philosophical, and theoretical – sets the stage for new work moving forward.
The End of Fun (An Enemy Novel #7)
by Charlie HigsonEveryday Reality is a Drag?.FUN¿-the latest in augmented reality-is fun but it's also frustrating, glitchy, and dangerously addictive . Just when everyone else is getting on, 17-year-old Aaron O'Faolain wants off.But first he has to complete his Application for Termination, and in order to do that he has to deal with his History-not to mention the present, including his grandfather's suicide and a series of clues that may (or may not) lead to buried treasure. As he attempts to unravel the mystery, Aaron is sidetracked again . . . and again. Shadowed by his virtual "best friend," Homie, Aaron struggles with love, loss, dog bites, community theater, wild horses, wildfires, and the fact (deep breath) that actual reality can sometimes surprise you.Sean McGinty's strikingly profound debut unearths a world that is eerily familiar, yet utterly original. Discover what it means to come to the end of fun.
The End of Fun (An Enemy Novel #7)
by Sean McGintyEveryday Reality is a Drag?.FUN¿-the latest in augmented reality-is fun but it's also frustrating, glitchy, and dangerously addictive . Just when everyone else is getting on, 17-year-old Aaron O'Faolain wants off.But first he has to complete his Application for Termination, and in order to do that he has to deal with his History-not to mention the present, including his grandfather's suicide and a series of clues that may (or may not) lead to buried treasure. As he attempts to unravel the mystery, Aaron is sidetracked again . . . and again. Shadowed by his virtual "best friend," Homie, Aaron struggles with love, loss, dog bites, community theater, wild horses, wildfires, and the fact (deep breath) that actual reality can sometimes surprise you.Sean McGinty's strikingly profound debut unearths a world that is eerily familiar, yet utterly original. Discover what it means to come to the end of fun.
The End of Gender: Debunking the Myths about Sex and Identity in Our Society
by Debra SohInternational sex researcher, neuroscientist, and columnist Debra Soh debunks popular gender myths in this research-based, scientific examination of the many facets of gender identity.Is our gender something we&’re born with, or are we conditioned by society? In The End of Gender, neuroscientist and sexologist Dr. Debra Soh uses a research-based approach to address this hot-button topic, unmasking popular misconceptions about the nature vs. nurture debate and exploring what it means to be a woman or a man in today&’s society. Both scientific and objective, and drawing on original research and carefully conducted interviews, Soh tackles a wide range of issues, such as gender-neutral parenting, gender dysphoric children, and and the neuroscience of being transgender. She debates today&’s accepted notion that gender is a social construct and a spectrum, and challenges the idea that there is no difference between how male and female brains operate. The End of Gender is a conversation-starting work that will challenge what you thought you knew about gender, identity, and everything in between. Timely, informative, and provocative, it will arm you with the facts you need to come to your own conclusions about gender identity and its place in the world today.
The End of Genetics: Designing Humanity's DNA
by David B. GoldsteinAn urgent plea for a broader understanding and awareness of the unconsidered dangers of new genetic technologies Since 2010 it has been possible to determine a person&’s genetic makeup in a matter of days at an accessible cost for many millions of people. Along with this technological breakthrough there has emerged a movement to use this information to help prospective parents &“eliminate preventable genetic disease.&” As the prospect of systematically excluding the appearance of unwanted mutations in our children comes within reach, David B. Goldstein examines the possible consequences from these types of choices. Engaging and accessible, this clarion call for responsible and informed stewardship of the human genome provides an overview of what we do and do not know about human genetics and looks at some of the complex, yet largely unexplored, issues we must be most careful about as we move into an era of increasing numbers of parents exercising direct control over the genomes of their children.
The End of Life as We Know It: Ominous News From the Frontiers of Science
by Michael Guillen"It's happening this second. Scientists are re-imagining and re-engineering the world forever. With brutal honesty and engaging story-telling, Michael Guillen gives us a clear-eyed look at a future that is already here. Consider this unsettling, brilliantly written, must-read book your official wake up call." -- ERIC METAXAS, #1 national bestselling author of Bonhoeffer: Pastor, Martyr, Prophet, Spy "Michael Guillen has tackled an important subject in The End of Life as We Know It... This book is a sobering look at where we could be headed. A fascinating read." -- DAVID LIMBAUGH, bestselling author of Jesus is Risen and The True Jesus In all aspects of life, humans are crossing lines of no return. Modern science is leading us into vast uncharted territory—far beyond the invention of nuclear weapons or taking us to the moon.Today, in labs all over the world, scientists are performing experiments that threaten to fundamentally alter the practical character and ethical color of our everyday lives. In The End of Life as We Know It: Ominous News from the Frontiers of Science, bestselling author and Emmy award winning science journalist Michael Guillen takes a penetrating look at how the scientific community is pushing the boundaries of morality, including: • Scientists who detached the head of a Russian man from his crippled, diseased body, and stitching it onto a healthy new donated body. • Fertility experiments aimed at allowing designer babies to be conceived with the DNA from three or more biological parents. • The unprecedented politicization of science – for example, in the global discussion about climate change that is pitting “deniers” against “alarmists” and inspiring Draconian legislation, censorship, and legal prosecutions. • The integration of Artificial Intelligence into communications and the economy. The End of Life as We Know It takes us into labratories and boardrooms where these troubling advances are taking place and asks the question no scientists seem to be asking: What does this mean for the future of humanity? PREVIOUS PRAISE FOR MICHAEL GUILLEN: “Guillen succeeds triumphantly…He writes with extraordinary grace and clarity.” — CHRISTOPHER LEHMANN-HAUPT, The New York Times “Guillen knows how to tell a story.” — Wall Street Journal “Michael Guillen is ‘Winsomely brilliant.’” — ERIC METAXAS, #1 national bestselling author of Bonhoeffer: Pastor, Martyr, Prophet, Spy “Michael Guillen bridges the seeming gap between science and faith better than anyone I know.” — CAL THOMAS, Syndicated and USA Today columnist/Fox News contributor
The End of Memory: A Natural History of Aging and Alzheimer's
by Jay IngramAn illuminating biography of "the plague of the twenty-first century" and scientists' efforts to understand and, they hope, prevent it, The End of Memory is a book for those who want to find out the true story behind an affliction that courses through families and wreaks havoc on the lives of millions.It is a wicked disease that robs its victims of their memories, their ability to think clearly, and ultimately their lives. For centuries, those afflicted by Alzheimer's disease have suffered its debilitating effects while family members sit by, watching their loved ones disappear a little more each day until the person they used to know is gone forever. The disease was first described by German psychologist and neurologist Alois Alzheimer in 1906. One hundred years and a great deal of scientific effort later, much more is known about Alzheimer's, but it still affects millions around the world, and there is no cure in sight.In The End of Memory, award-winning science author Jay Ingram writes a biography of this disease that attacks the brains of patients. He charts the history of the disease from before it was noted by Alois Alzheimer through to the twenty-first century, explains the fascinating science of plaques and tangles, recounts the efforts to understand and combat the disease, and introduces us to the passionate researchers who are working to find a cure.
The End of Night: Searching for Natural Darkness in an Age of Artificial Light
by Paul BogardA deeply panoramic tour of the night, from its brightest spots to the darkest skies we have left. A starry night is one of nature's most magical wonders. Yet in our artificially lit world, three-quarters of Americans' eyes never switch to night vision and most of us no longer experience true darkness. In THE END OF NIGHT, Paul Bogard restores our awareness of the spectacularly primal, wildly dark night sky and how it has influenced the human experience across everything from science to art. From Las Vegas' Luxor Beam--the brightest single spot on this planet--to nights so starlit the sky looks like snow, Bogard blends personal narrative, natural history, science, and history to shed light on the importance of darkness--what we've lost, what we still have, and what we might regain--and the simple ways we can reduce the brightness of our nights tonight.
The End of Physics: The Myth of a Unified Theory
by David LindleyThe history of physics and its reinterpretation.
The End of Pink (American Poets Continuum)
by Kathryn NuernbergerWinner of the 2015 James Laughlin Award, Kathryn Nuernberger's The End of Pink is populated by strange characters—Bat Boy, automatons, taxidermied mermaids, snake oil salesmen, and Benjamin Franklin—all from the annals of science and pseudoscience. Equal parts fact and folklore, these poems look to the marvelous and the weird for a way to understand childbirth, parenthood, sickness, death, and-of course—joy.
The End of Rationality and Selfishness: A Story on the Asymmetry, Uncertainty and the Evolution of Cooperation
by Rui-Wu WangThis book reviews the antinomy of rationality and selfishness raised from egoism, though rationality and selfishness are understood as basic evolutionary dynamics of humans and other organisms in both classical economics and evolutionary biology. Based on the research and a comparison with human’s social cooperative behavior, the author presents his belief that the social cooperative system, in its essence, cooperation and conflict are of uncertain stochasticity resulting from their intrinsic asymmetric interaction between cooperative partners. The book then discusses limitations of Newton’s methodology of monism in both biology and social science. The understanding of the asymmetric and uncertain characteristics found in cooperation system needs perspective of quantum physics of pluralism. At the end of the book, the author undertakes a review of consistency of Newtonian and monism philosophy and the links between quantum physics and pluralism philosophy.
The End of Science: Facing The Limits Of Knowledge In The Twilight Of The Scientific Age
by John HorganIn The End of Science, John Horgan makes the case that the era of truly profound scientific revelations about the universe and our place in it is over. Interviewing scientific luminaries such as Stephen Hawking, Francis Crick, and Richard Dawkins, he demonstrates that all the big questions that can be answered have been answered, as science bumps up against fundamental limits. The world cannot give us a "theory of everything,” and modern endeavors such as string theory are "ironic” and "theological” in nature, not scientific, because they are impossible to confirm. Horgan’s argument was controversial in 1996, and it remains so today, still firing up debates in labs and on the internet, not least because--as Horgan details in a lengthy new introduction--ironic science is more prevalent than ever. Still, while Horgan offers his critique, grounded in the thinking of the world’s leading researchers, he offers homage, too. If science is ending, he maintains, it is only because it has done its work so well.
The End Of Science
by John HorganThis provocative bestseller explores the entire scientific landscape through the eyes of the world's leading scholars and sheds light on what the future of science is and what science holds for the future as a civilization. Noam Chomsky, Stephen Hawking, Karl Popper and others give their candid reflections on everything from the implications of chaos theory to the existence of God, challenging some of the most basic assumptions about the world.
The End of Sex and the Future of Human Reproduction
by Henry T. GreelyWithin 40 years many people will stop having sex for reproduction. After IVF and preimplantation genetic diagnosis, parents will pick embryos for implantation, gestation, and birth. It will be easy, safe, lawful, and free, Henry Greely predicts. He explains the new technologies and sets out the deep ethical and legal challenges facing humanity.
The End of Stress: Four Steps to Rewire Your Brain
by Don Joseph GoeweyRid yourself of stress and live a richly beautiful life filled with the joy you deserve! Using a simple method, The End of Stress shows you how to change your brain&’s default reaction from stress, anxiety, and depression to calm, creativity, and happiness. Have you been struggling with your levels of stress, unable to escape it completely? It&’s not your fault. We were brought up in a fear-based, shame-based culture that wired our brains&’ default systems to stress and fear—triggering all sorts of stress reactions that sabotage happiness, compromise health, and block our potential to flourish. If ignored too long, long-term stress can become deadly, resulting in a build-up of toxic stress hormones in your body, shrinking your brain mass and lowering optimum brain function, depressing your emotional set point, and shortening your lifespan. There&’s now proof that the deadly long-term effects of stress are reversable and The End of Stress provides four steps to better achieve success and happiness. This specific shift literally rewires the brain to deliver the full measure of intelligence, creativity, and emotional balance that enables you to thrive instead of struggle. The End of Stress: Four Steps to Rewire Your Brain guides you through an evidence-based process that achieves this powerful shift. This book is designed as a workshop-in-a-book, supported by a website of tools, audio files, and materials that can help create a new and healthier you!
The End of the Beginning: Cancer, Immunity, And The Future Of A Cure
by Michael KinchA fascinating history of our understanding and the treatment of cancer by one of the leading figures in the field—who is also a pioneer on the cusp of a breakthrough. For the first time since a 5th century Greek physician gave the name “cancer” (karkinos, in Greek) to a deadly disease first described in Egyptian Papyri, the medical world is near a breakthrough that could allow even the most conservative doctors and pragmatic patients to use the other “c word” – cure – in the same sentence as cancer. A remarkable series of events has brought us to this point, thanks in large part to a new ability to more efficiently harness the extraordinary power of the human immune. The End of the Beginning is a remarkable history of cancer treatment and the evolution of our understanding of its dynamic interplay with the immune system. Through Michael Kinch’s personal experience as a cancer researcher at Washington University and the head of the oncology program at a leading biotechnology company, we witness the incredible accumulation of breakthrough science and its rapid translation into life-saving technologies that have begun to dramatically increase the quality and quantity of life for cancer patients. Expanding upon Kinch’s own remarkable projects to encompass the vaccines being deployed to eliminate cervical cancer, the development of cancer-specific “smart bombs” in the form of monoclonal antibodies, cellular therapies, and checkpoint inhibitors—The End of the Beginning reveals the incredible transformation of cancer treatment happening today. Kinch details the remarkable history of people, science, technology and disease and presents thrilling next-generation technologies that hold the promise to eliminate cancer for some, and perhaps ultimately, for all.
End of the Earth: Voyages to Antarctica
by Peter Matthiessen"Matthiessen chronicles two voyages into the frozen seas that surround a landmass larger than the continental United States, most of it buried under eternal snow and ice as much as three miles deep. Ninety percent of the world's fresh water is locked in this immense ice cap, a remote region profoundly important to our environment. The author addresses the subject with authority and passion, discussing everything from global warming and the ozone layer to the vital role of krill, the teeming crustacean that is the cornerstone of the marine food chain." "Nature lovers - birders especially - will be fascinated by descriptions of more than half of the penguin species and an astonishing array of seabirds, from tiny storm-petrels to magnificent albatrosses, which may soar for years without alighting on land; here too are close encounters with whales, leopard seals, and elephant seals, and elusive creatures such as the oceanic orca. There are also remarkable descriptions of the seldom seen polar rookeries where thousands of emperor penguins stand motionless for months at a time, brooding their giant eggs through the long, cold darkness of Antarctic winter."--BOOK JACKET.
The End of the Long Summer: Why We Must Remake Our Civilization to Survive On A Volatile Earth
by Dianne DumanoskiFor the past twelve thousand years, Earth’s stable climate has allowed human civilization to flourish. But this long benign summer is an anomaly in the Earth’s history and one that is rapidly coming to a close. The radical experiment of our modern industrial civilization is now disrupting our planet’s very metabolism; our future hinges in large part on how Earth responds. Climate change is already bearing down, hitting harder and faster than expected. The greatest danger is not extreme yet discrete weather events, such as Hurricane Katrina or the calamitous wildfires that now plague California, but profound and systemic disruptions on a global scale. Contrary to the pervasive belief that climate change will be a gradual escalator ride into balmier temperatures, the Earth’s climate system has a history of radical shifts–dramatic shocks that could lead to the collapse of social and economic systems. The question is no longer simply how can we stop climate change, but how can we as a civilization survive it. The guiding values of modern culture have become dangerously obsolete in this new era. Yet as renowned environmental journalist Dianne Dumanoski shows, little has been done to avert the crisis or to prepare human societies for a time of growing instability. In a work of astonishing scope, Dumanoski deftly weaves history, science, and culture to show how the fundamental doctrines of modern society have impeded our ability to respond to this crisis and have fostered an economic globalization that is only increasing our vulnerability at this critical time. She exposes the fallacy of banking on a last-minute technological fix as well as the perilous trap of believing that humans can succeed in the quest to control nature. Only by restructuring our global civilization based on the principles that have allowed Earth’s life and our ancestors to survive catastrophe——diversity, redundancy, a degree of self-sufficiency, social solidarity, and an aversion to excessive integration——can we restore the flexibility needed to weather the trials ahead. In this powerful and prescient book, Dumanoski moves beyond now-ubiquitous environmental buzzwords about green industries and clean energy to provide a new cultural map through this dangerous passage. Though the message is grave, it is not without hope. Lucid, eloquent, and urgent,The End of the Long Summerdeserves a place alongside transformative works such asSilent SpringandThe Fate of the Earth. From the Hardcover edition.
End of the Megafauna: The Fate Of The World's Hugest, Fiercest, And Strangest Animals
by Peter Schouten Ross D MacPheeThe fascinating lives and puzzling demise of some of the largest animals on earth. Until a few thousand years ago, creatures that could have been from a sci-fi thriller—including gorilla-sized lemurs, 500-pound birds, and crocodiles that weighed a ton or more—roamed the earth. These great beasts, or “megafauna,” lived on every habitable continent and on many islands. With a handful of exceptions, all are now gone. What caused the disappearance of these prehistoric behemoths? No one event can be pinpointed as a specific cause, but several factors may have played a role. Paleomammalogist Ross D. E. MacPhee explores them all, examining the leading extinction theories, weighing the evidence, and presenting his own conclusions. He shows how theories of human overhunting and catastrophic climate change fail to account for critical features of these extinctions, and how new thinking is needed to elucidate these mysterious losses. Along the way, we learn how time is determined in earth history; how DNA is used to explain the genomics and phylogenetic history of megafauna—and how synthetic biology and genetic engineering may be able to reintroduce these giants of the past. Until then, gorgeous four-color illustrations by Peter Schouten re-create these megabeasts here in vivid detail.
The End of the River: Dams, Drought and Déjà Vu on the Rio São Francisco
by Brian Harvey&“[Harvey] may have created a new literary genre: science travel writing . . . travelogue, autobiography, history, and even fantasy romp alongside the biology&” (Quill & Quire). When biologist Brian Harvey saw a thousand fish blundering into a Brazilian dam, he asked the obvious: What&’s going to happen to them? The End of the River is the story of his long search for an answer. Harvey takes readers from a fisheries patrol boat on the Fraser River to the great Tsukiji fish market in Japan, with stops in the Philippines, Thailand, and assorted South American countries. Finally, in the arid outback of northeast Brazil, against a backdrop of a multi-billion-dollar river project nobody seems to want, he finds a small-scale answer to his simple question. In recounting his journey, he populates his story with characters both real and imagined, human and otherwise—a six-foot endangered catfish; a Canadian professor with a weakness for Thai bar girls; a chain-smoking Brazilian with a passion for her river; a drug-addled stick-up artist. The End of the River is about fishermen, fish farmers, and fish cops; there are scientists and shysters as well as a few Colombian narcotráficos and some very drunk, very hairy Brazilian men in thongs. From the founder of the World Fisheries Trust, Harvey introduces a new kind of writing about the environment, as far off the beaten track as you can get in a Land Rover driven by a female Colombian biologist whose favorite expression is &“No hay via!&”—meaning, &“no road!&” &“[A] freewheeling and vividly written essay on the mysteries and longings of what it is to be human in a world of cynicism and loss—and more significantly, what it is to be hopeful, to persevere, in the search for redemption and beauty . . . A brilliant and instructive book . . . recalls the travel writing of one of Harvey&’s heroes, Sir Richard Burton.&” —The Globe and Mail (Toronto)
The End of Time: The Maya Mystery of 2012
by Anthony AveniDecember 21, 2012. The Internet, bookshelves, and movie theaters are full of prophecies, theories, and predictions that this date marks the end of the world, or at least the end of the world as we know it. Whether the end will result from the magnentic realignment of the north and south poles, bringing floods, earthquakes, death, and destruction; or from the return of alien caretakers to enlighten or enslave us; or from a global awakening, a sudden evolution of Homo sapiens into non-corporeal beings—theories of great, impending changes abound. In The End of Time, award-winning astronomer and Maya researcher Anthony Aveni explores these theories, explains their origins, and measures them objectively against evidence unearthed by Maya archaeologists, iconographers, and epigraphers. He probes the latest information astronomers and earth scientists have gathered on the likelihood of Armageddon and the oft-proposed link between the Maya Long Count cycle and the precession of the equinoxes. He then expands on these prophecies to include the broader context of how other cultures, ancient and modern, thought about the “end of things” and speculates on why cataclysmic events in human history have such a strong appeal within American pop culture.
End Times: A Brief Guide to the End of the World
by Bryan WalshWhat is going to cause our extinction?How can we save ourselves and our future?End Times answers the most important questions facing humankindEnd Times is a compelling work of skilled reportage that peels back the layers of complexity around the unthinkable-and inevitable-end of humankind. From asteroids and artificial intelligence to volcanic supereruption to nuclear war, 15-year veteran science reporter and TIME editor Bryan Walsh provides a stunning panoramic view of the most catastrophic threats to the human race.In End Times, Walsh examines threats that emerge from nature and those of our own making: asteroids, supervolcanoes, nuclear war, climate change, disease pandemics, biotechnology, artificial intelligence, and extraterrestrial intelligence. Walsh details the true probability of these world-ending catastrophes, the impact on our lives were they to happen, and the best strategies for saving ourselves, all pulled from his rigorous and deeply thoughtful reporting and research.Walsh goes into the room with the men and women whose job it is to imagine the unimaginable. He includes interviews with those on the front lines of prevention, actively working to head off existential threats in biotechnology labs and government hubs. Guided by Walsh's evocative, page-turning prose, we follow scientific stars like the asteroid hunters at NASA and the disease detectives on the trail of the next killer virus.Walsh explores the danger of apocalypse in all forms. In the end, it will be the depth of our knowledge, the height of our imagination, and our sheer will to survive that will decide the future.