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Endless Novelties of Extraordinary Interest: The Voyage of H.M.S. Challenger and the Birth of Modern Oceanography
by Doug MacdougallA gripping tale of exploration aboard H.M.S. Challenger, an expedition that laid the foundations for modern oceanography From late 1872 to 1876, H.M.S. Challenger explored the world’s oceans. Conducting deep sea soundings, dredging the ocean floor, recording temperatures, observing weather, and collecting biological samples, the expedition laid the foundations for modern oceanography. Following the ship’s naturalists and their discoveries, earth scientist Doug Macdougall engagingly tells a story of Victorian-era adventure and ties these early explorations to the growth of modern scientific fields. In this lively story of discovery, hardship, and humor, Macdougall examines the work of the expedition’s scientists, especially the naturalist Henry Moseley, who rigorously categorized the flora and fauna of the islands the ship visited, and the legacy of John Murray, considered the father of modern oceanography. Macdougall explores not just the expedition itself but also the iconic place that H.M.S. Challenger has achieved in the annals of ocean exploration and science.
The Endless Quest: Helping America's Farm Workers
by Philip L Martin David A MartinA work which traces the development of US Government programmes designed to help migrant farm workers, showing how the programmes operate today and explaining why they are failing to remedy the problems they were designed to solve.
Endless Universe: Beyond the Big Bang
by Paul J. Steinhardt Neil TurokThe first serious challenge to the widely accepted 'Big Bang' model of the universe. According to 'Big Bang' theory, space and time sprang into existence fifteen billion years ago: a super-heated fireball of near infinite density that expanded at phenomenal speed. As it continued to expand, it cooled and condensed to create the galaxies, stars and planets we see today. But the theory has always had flaws and they have become increasingly difficult to reconcile. Why is the distribution of matter and ra...
The Endless Web: Fascial Anatomy and Physical Reality
by R. Louis Schultz Rosemary Feitis Ronald Thompson Diana SallesThe result of more than two decades of research and practice, The Endless Web presents in clear, readable language a comprehensive guide to understanding and working effectively with the myofascial system, the 'packing material' of the body. Myofascia is a flexible network of tissue that surrounds, cushions, and supports muscles, bones, and organs. It also acts as a riverbed containing the flow of interstitial fluid, and is a critical influence on the immune and hormonal systems. In daily life, this connective tissue is an underlying determinant of movement quality, modd, alertness, and general well-being. The Endless Web is a fully illustrated guide to understanding how myofascia works, it supportive role within the body's anatomy, and how gentle manipulation of the myofascial tissue is central to lasting therapeutic intervention and how it can be integrated into any bodywork practice.
Endlessly Green
by Savita HiremathEndlessly Green looks at the history, the science and the art of composting and sustainable waste management through a kaleidoscope of philosophical, moral and ethical intricacies. The author digs into her rich pool of experiential learnings and raw inputs gathered through a decade of research, legwork and fearless execution. This engaging field guide equips community volunteers, activists, students, SWM practitioners and professionals with practical inputs on segregation, composting and organic gardening/farming, making sustainability imaginable in a concrete jungle. In doing so, it helps individuals discover the possibilities of bringing about a change in their environment by engaging their own environmental sensibilities. Endlessly Green is an extraordinary celebration of things small and significant and the fight against waste, culminating in a replicable and scalable end-to-end solution.
Endlich Biochemie verstehen
by Jonathan Wolf MuellerDieses Buch beantwortet brennende Fragen nach dem (molekularen) Sinn des Lebens und macht Lust auf mehr. Was ist es denn „was die Welt, im Innersten zusammenhält“. Das Buch ist als Lehrbuch konzipiert und macht übergeordnete Konzepte der Biochemie mit einfachen Bildern begreifbar. Die Konzepte oder spannenden Fragen der Kapitel werden mit viel Witz und über einfache Eselsbrücken den Studierenden näher gebracht.
EndNote 1-2-3 Easy!: Reference Management for the Professional
by Abha Agrawal Majid RasouliThis book is intended for healthcare professionals, biomedical researchers, health policy experts, and graduate students who frequently write and publish scientific manuscripts in peer reviewed journals. This new edition updates earlier versions with an emphasis on the most currently available Clarivate Analytics software application EndNote X9, a widely used reference management software. For first-time users of EndNote X9, this book is a comprehensive and well-illustrated instruction manual for getting started, including detailed instructions on installation, creating reference libraries, and ultimately creating complete and accurate citation-based bibliographies necessary to achieve successful peer reviewed publications. There is also a full chapter devoted to careful guidance for the growing practice of citing references from online internet sources. For existing “power users” of current and earlier versions of EndNote, this book provides quick and easy access to a comprehensive compendium of nuanced and advanced features of this powerful software, with an emphasis on providing greater ease and control in coordinating and curating research materials and bibliographies with research collaborators and scientific writing teams. The authors have also added new, state-of-the-art “how-to” guidance on a variety of methods of using EndNote, including PubMed, Google Scholar, Web of Science, Scopus and others. Like many legacy software systems, Clarivate Analytics has also begun to offer an online “desktop” version of EndNote, a topic which is now also covered in Chapter 10 (EndNote Online) of this new edition.
EndNote 1-2-3 Easy!: Reference Management for the Professional
by Abha Agrawal Majid RasouliThis book is intended for students, academics, authors, and research-oriented professionals to store, organize, and manage their references for research papers, theses, dissertations, journal articles, and other publications. Its purpose is to educate readers about effective use of information technology in reference management - the process of storing, managing, retrieving and citing scientific references. It also provides step-by-step instruction on using EndNote, a popular reference management software. Since the publication of the third edition, substantial changes have taken place in the field of reference management. EndNote has released a new version – EndNote 20. The web-based knowledge databases such as Web of Science Core Collection, Scopus, and Google Scholar are also being used far more frequently. The fourth edition of EndNote 1-2-3 Easy! incorporates updated instructions and screenshots to ensure that the readers continue to find this a user-friendly book providing accurate and reliable information. For first-time users of EndNote 21, this book is a comprehensive and well-illustrated instruction manual for getting started, including detailed instructions on installation, creating reference libraries, and ultimately creating complete and accurate citation-based bibliographies necessary to achieve successful peer reviewed publications. For existing “power users” of current and earlier versions of EndNote, this book provides quick and easy access to a comprehensive compendium of nuanced and advanced features of this powerful software, with an emphasis on providing greater ease and control in coordinating and curating research materials and bibliographies with research collaborators and scientific writing teams.
(Endo)symbiotic Methanogenic Archaea
by Johannes H. HacksteinThis updated monograph deals with methanogenic endosymbionts of anaerobic protists, in particular ciliates and termite flagellates, and with methanogens in the gastrointestinal tracts of vertebrates and arthropods. Further chapters discuss the genomic consequences of living together in symbiotic associations, the role of methanogens in syntrophic degradation, and the function and evolution of hydrogenosomes, hydrogen-producing organelles of certain anaerobic protists. Methanogens are prokaryotic microorganisms that produce methane as an end-product of a complex biochemical pathway. They are strictly anaerobic archaea and occupy a wide variety of anoxic environments. Methanogens also thrive in the cytoplasm of anaerobic unicellular eukaryotes and in the gastrointestinal tracts of animals and humans. The symbiotic methanogens in the gastrointestinal tracts of ruminants and other “methanogenic” mammals contribute significantly to the global methane budget; especially the rumen hosts an impressive diversity of methanogens. This makes this updated volume an interesting read for scientists and students in Microbiology and Physiology.
Endocannabinoid Signaling
by Mauro MaccarroneThisvolume encompasses all major methodologies to interrogate endocannabinoidsystems (ECS) and endocannabinoids (eCBs) signaling. With increasing interesttowards the manifold activities of eCBs, this book discusses the chemical,biochemical, and molecular biological assays, and activity of distinct elementsof the ECS. These include membrane, nuclear receptors, biosynthetic andhydrolytic enzymes, and membrane transporters and oxidative enzymes. Written inthe highly successful Methods in Molecular Biology series format,chapters include introductions to their respective topics, lists of thenecessary materials and reagents, step-by-step, readily reproducible laboratoryprotocols, and tips on troubleshooting and avoiding known pitfalls. Timely and cutting edge, Endocannabinoid Signaling: Methods and Protocolsis a valuable resource and will help chemists, drug designers, biochemists,molecular biologists, cell biologists, pharmacologists, and (electro)physiologists navigate the mare magnum of endocannabinoid research.
Endocannabinoid Signaling: Methods and Protocols (Methods in Molecular Biology #2576)
by Mauro MaccarroneThis second edition provides new and updated chapters detailing all major elements of the ECB system. Chapters guide readers through identification of drug targets, electrophysiology, computational chemistry, and machine learning. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Endocannabinoid Signaling: Methods and Protocols, Second Edition is a valuable resource for all researchers interested in learning more about this important and developing field.
endoCANNABINOIDS
by Roger G Sorensen Mary E. Abood Nephi StellaThis book is intended as a scientific resource for cannabinoid researchers carrying out animal and human experiments, and for those who are interested in learning about future directions in cannabinoid research. Additionally, this book may be of value to investigators currently working outside the field of cannabinoid research who have an interest in learning about these compounds and their atypical cannabinoid signalling. This book provides insight into the potential medical application of cannabinoids and their therapeutic development for the treatment of human disease.
Endocrine and Metabolic Disorders: Clinical Lab Testing Manual, Fourth Edition
by Robert F. Dons Frank H. Wians Jr.Bottom Line Information to Effectively Diagnose DisordersThe diagnosis, management, and clinical testing associated with old, traditional, and new endocrine disorders have seen numerous advances during the past 10 years since the publication of the previous edition of this bestselling resource. Updating its classic predecessor in content and format
Endocrine Disrupters: Hazard Testing and Assessment Methods
by Peter MatthiessenEnables researchers to assess the effects of endocrine disrupters as well as comply with new environmental regulations Endocrine disrupters are chemicals—both man-made and natural—that interfere with the body's endocrine system, potentially resulting in adverse developmental, reproductive, neurological, and immune effects. In recent years, a number of regulatory authorities around the world have drafted or enacted legislation that requires the detection and assessment of the effects of endocrine disrupters on both humans and wildlife. In response, this book provides comprehensive, up-to-date information on the latest tested and proven methods used to detect and assess the environmental hazards posed by endocrine-disrupting chemicals. Endocrine Disrupters is divided into chapters covering each major taxon as well as chapters dedicated to hazard assessment and regulation. The book covers testing methods for all the vertebrate groups and several invertebrate phyla, including: Crustaceans and mollusks Insects Fish Amphibians and reptiles Birds and mammals Moreover, the book emphasizes practical, ethical testing methods that combine sensitivity, efficiency, statistical power, and reasonable cost. Each chapter is written by one or more international experts in ecotoxicology, offering readers step-by-step guidance for implementing each method based on the latest research and the authors' firsthand laboratory experience. Furthermore, all the chapters have been subjected to a rigorous peer review and edited in light of the reviewers' comments. References at the end of each chapter guide readers to the literature in the field. Endocrine Disrupters is recommended for scientists who need to test chemicals for possible endocrine-disrupting properties. It is also recommended for regulatory authorities who need to decide whether particular chemicals can be safely marketed.
Endocrine Disrupters in Wastewater and Sludge Treatment Processes
by Jason W. Birkett John N. LesterEndocrine Disrupting Chemicals (EDCs) have been shown to produce changes in the endocrine system of organisms, leading to increases in cancers and abnormalities in reproductive structure and function. This book presents research on the endocrine-disrupting effects of sewage and industrial effluents, covering the sources, fate, and transport of EDCs
Endocrine Disrupting Chemicals-induced Metabolic Disorders and Treatment Strategies (Emerging Contaminants and Associated Treatment Technologies)
by Muhammad Zaffar Hashmi Muhammad Sajid Hamid Akash Kanwal RehmanThis volume offers a detailed and comprehensive analysis of Endocrine Disrupting Chemicals (EDCs), covering their occurrence, exposure to humans and the mechanisms that lead to the parthogenesis of EDCs-induced metabolic disorders. The book is divided into three parts. Part I describes the physiology of the human endocrine system, with special emphasis on various types of metabolic disorders along with risk factors that are responsible for the development of these disorders. Part II addresses all aspects of EDCs, including their role in the induction of various risk factors that are responsible for the development of metabolic disorders. Part III covers up-to-date environmental regulatory considerations and treatment strategies that have been adopted to cure and prevent EDCs-induced metabolic disorders. This section will primarily appeal to clinicians investigating the causes and treatment of metabolic disorders. The text will also be of interest to students and researchers in the fields of Environmental Pharmacology and Toxicology, Environmental Pollution, Pharmaceutical Biochemistry, Biotechnology, and Drug Metabolism/Pharmacokinetics.
Endocrine Disruption Modeling (QSAR in Environmental and Health Sciences)
by James DevillersUses Computational Tools to Simulate Endocrine Disruption PhenomenaEndocrine Disruption Modeling provides a practical overview of the current approaches for modeling endocrine activity and the related potential adverse effects they may induce on environmental and human health. Based on the extensive research of an international panel of contributor
Endocrine Disruptors and Puberty
by Andrea C. Gore Evanthia Diamanti-KandarakisEndocrine disruption represents one of the most controversial environmental issues of our time. Mounting evidence stemming from more than 10 years of experimental, epidemiological and clinical studies has transformed the once generally discounted subject of endocrine disruptors into an issue of tremendous concern not only within the scientific community but among society as a whole. Following initial evidence from basic research, endocrine disruption in humans has now emerged as a major medical challenge. In this respect, puberty, a crucial developmental stage, has been definitively identified as a key window of vulnerability with regard to endocrine disruptors. Written by leading authorities in the field, Endocrine Disruptors and Puberty offers an engaging and comprehensive overview of this fascinating and rapidly growing problem. An indispensable resource for all clinicians and scientists interested in this challenging endocrinologic topic, Endocrine Disruptors and Puberty is a timely contribution that will help navigate a path toward understanding the problem and developing solutions.
Endocrine Pathology (Encyclopedia of Pathology)
by Stefano La Rosa Silvia UccellaThis encyclopedia volume covers the complete field of endocrine pathology – from Acidophil Stem Cell Adenoma to Waterhouse-Friderichsen syndrome. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.
Endocrine Toxicology (Target Organ Toxicology Series)
by J. Charles Eldridge James T. StevensWith contributions by international experts in academia, chemical manufacturing, government research laboratories, regulatory agencies, and private consulting, this guide explores the potentially damaging influence of environmental agents on the endocrine system. It examines endocrine toxicology's increased importance in environmental safety issues
Endocrine Toxicology (Target Organ Toxicology Series)
by John A. Thomas Howard D. ColbyThis text presents a range of topics from the molecular events surrounding hormone actions to epidemiologic studies of the effects of environmental and occupational chemicals on reproductive organs. The endocrine systems covered include the adrenal cortex, thyroid and parathyroid, gonads, and the endocrine pancreas. Of particular importance are the
Endocrinology of Social Relationships
by Peter T. Ellison Peter B. GrayIn social relationships―whether between mates, parents and offspring, or friends―we find much of life’s meaning. But in these relationships, so critical to our well-being, might we also detect the workings, even directives, of biology? This book, a rare melding of human and animal research and theoretical and empirical science, ventures into the most interesting realms of behavioral biology to examine the intimate role of endocrinology in social relationships. <P><P>The importance of hormones to reproductive behavior―from breeding cycles to male sexual display―is well known. What this book considers is the increasing evidence that hormones are just as important to social behavior. Peter Ellison and Peter Gray include the latest findings―both practical and theoretical―on the hormonal component of both casual interactions and fundamental bonds. The contributors, senior scholars and rising scientists whose work is shaping the field, go beyond the proximate mechanics of neuroendocrine physiology to integrate behavioral endocrinology with areas such as reproductive ecology and life history theory. Ranging broadly across taxa, from birds and rodents to primates, the volume pays particular attention to human endocrinology and social relationships, a focus largely missing from most works of behavioral endocrinology.
Endocytosis and Signaling (Progress in Molecular and Subcellular Biology #57)
by Christophe Lamaze Ian PriorThis book focuses on the context dependency of cell signaling by showing how the endosomal system helps to structure and regulate signaling pathways. The location and concentration of signaling nodes regulate their activation cycles and engagement with distinct effector pathways. Whilst many cell signaling pathways are initiated from the cell surface, endocytosis provides an opportunity for modulating signaling networks’ output. In this book, first a series of reviews describe the endocytic and endosomal system and show how these subcellular platforms sort and regulate a wide range of signaling pathway components and phenotypic outputs. The book then reviews the latest scientific insights into how endocytic trafficking and subcellular location modulate a set of major pathways that are essential to normal cellular function and organisms’ development.
Endocytosis in Plants
by Jozef ŠamajEndocytosis is a fundamental cellular process by means of which cells internalize extracellular and plasma membrane cargos for recycling or degradation. It is important for the establishment and maintenance of cell polarity, subcellular signaling and uptake of nutrients into specialized cells, but also for plant cell interactions with pathogenic and symbiotic microbes. Endocytosis starts by vesicle formation at the plasma membrane and progresses through early and late endosomal compartments. In these endosomes cargo is sorted and it is either recycled back to the plasma membrane, or degraded in the lytic vacuole. This book presents an overview of our current knowledge of endocytosis in plants with a main focus on the key molecules undergoing and regulating endocytosis. It also provides up to date methodological approaches as well as principles of protein, structural lipid, sugar and microbe internalization in plant cells. The individual chapters describe clathrin-mediated and fluid-phase endocytosis, as well as flotillin-mediated endocytosis and internalization of microbes. The book was written for a broad spectrum of readers including students, teachers and researchers.
Endogenous ADP-Ribosylation
by Friedrich Koch-NolteThis volume gathers the latest exciting findings on ADP-ribosylation from renowned experts in the field. It includes ten chapters, organized into the following three thematic sections: · Evolution and detection of endogenous ADP-ribosylation · ADP-ribosylation by the ARTC family of ADP-ribosyltransferases (R-S-E ARTs) · ADP-ribosylation by the ARTD family of ADP-ribosyltransferases (H-Y-E ARTs) The book will provide readers a better understanding of ADP-ribosylating toxins and their endogenous relatives. This provides a basis for developing novel toxin-neutralizing drugs and drugs targeting endogenous ADP-ribosyltransferase relatives.