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Extreme Particle Acceleration in Microquasar Jets and Pulsar Wind Nebulae with the MAGIC Telescopes (Springer Theses)
by Alba Fernández BarralThis exhaustive work sheds new light on unsolved questions in gamma-ray astrophysics. It presents not only a complete introduction to the non-thermal Universe, but also a description of the Imaging Atmospheric Cherenkov technique and the MAGIC telescopes. The Fermi-LAT satellite and the HAWC Observatory are also described, as results from both are included. The physics section of the book is divided into microquasars and pulsar wind nebulae (PWNe), and includes extended overviews of both. In turn, the book discusses constraints on particle acceleration and gamma-ray production in microquasar jets, based on the analyses of MAGIC data on Cygnus X-1, Cygnus X-3 and V404 Cygni. Moreover, it presents the discovery of high-energy gamma-ray emissions from Cygnus X-1, using Fermi-LAT data. The book includes the first joint work between MAGIC, Fermi-LAT and HAWC, and discusses the hypothetical PWN nature of the targets in depth. It reports on a PWN population study that discusses, for the first time, the importance of the surrounding medium for gamma-ray production, and in closing presents technical work on the first Large-Size-Telescope (LST; CTA Collaboration), along with a complete description of the camera.
Extreme physics
by Jeff Colvin Jon LarsenMost matter in the Universe, from the deep interior of planets to the core of stars, is at high temperature or high pressure compared to the matter of our ordinary experience. This book offers a comprehensive introduction to the basic physical theory on matter at such extreme conditions and the mathematical modeling techniques involved in numerical simulations of its properties and behavior. Focusing on computational modeling, the book discusses topics such as the basic properties of dense plasmas; ionization physics; the physical mechanisms by which laser light is absorbed in matter; radiation transport in matter; the basics of hydrodynamics and shock-wave formation and propagation; and numerical simulation of radiation-hydrodynamics phenomenology. End-of-chapter exercises allow the reader to test their understanding of the material and introduce additional physics, making this an invaluable resource for researchers and graduate students in this broad and interdisciplinary area of physics.
Extreme Science: The Highway of Light and Other Man-Made Wonders
by Peter Jedicke Scientific AmericanThese 34 Scientific American selections from 1995-1999 explore extreme construction projects (e.g., the world's longest suspension bridge and tallest buildings); and developments in transportation by air, space, sea, and road. Includes illustrations and suggested reading.
Extreme Science: Chasing the Ghost Bat
by Peter Jedicke Scientific AmericanFrom the pages of Scientific American comes the latest information and explorations into the bizarre realm of the natural world, including:-Our oldest relatives and the discovery of missing links-Strange predators, from flesh-eating chimps to the lethal Komodo dragon-Strange plant life, such as the carnivorous Venus's flytrap and the Voodoo lily-Extinct monsters, and giant, flightless, flesh-eating birds-Mysterious denizens of the deep, such as the giant squid and the slime hag-Insect oddities: fire ants, singing caterpillars, and Africanized bees
Extreme Science: Transplanting Your Head And Other Feats of the Future
by Peter Jedicke The Editors of Scientific AmericanFrom the pages of Scientific American comes the latest information and explorations into the futuristic world of biotechnology. -Recent breakthroughs in human longevity and life extension -Tissue engineering and the regeneration of limbs and organs -Biochemistry, from transgenic crops to biological warfare -The results and ramifications of the Human Genome Project -The current and future state of cloning and artificial wombs -Radical biotech: head transplants, artificial intelligence, and virtual senses
Extreme States of Matter
by Vladimir E. FortovWith its many beautiful colour pictures, this book gives fascinating insights into the unusual forms and behaviour of matter under extremely high pressures and temperatures. These extreme states are generated, among other things, by strong shock, detonation and electric explosion waves, dense laser beams, electron and ion beams, hypersonic entry of spacecraft into dense atmospheres of planets and in many other situations characterized by extremely high pressures and temperatures. Written by one of the world's foremost experts on the topic, this book will inform and fascinate all scientists dealing with materials properties and physics and also serve as an excellent introduction to plasma-, shock-wave and high-energy-density physics for students and newcomers seeking an overview. This second edition is thoroughly revised and expanded, in particular with new material on high energy-density physics, nuclear explosions and other nuclear transformation processes.
Extreme States of Matter in Strong Interaction Physics: An Introduction (Lecture Notes in Physics #841)
by Helmut SatzThis book is a course-tested primer on the thermodynamics of strongly interacting matter – a profound and challenging area of both theoretical and experimental modern physics. Analytical and numerical studies of statistical quantum chromodynamics provide the main theoretical tool, while in experiments, high-energy nuclear collisions are the key for extensive laboratory investigations. As such, the field straddles statistical, particle and nuclear physics, both conceptually and in the methods of investigation used. The book addresses, above all, the many young scientists starting their scientific research in this field, providing them with a general, self-contained introduction that highlights the basic concepts and ideas and explains why we do what we do. Much of the book focuses on equilibrium thermodynamics: first it presents simplified phenomenological pictures, leading to critical behavior in hadronic matter and to a quark-hadron phase transition. This is followed by elements of finite temperature lattice QCD and an exposition of the important results obtained through the computer simulation of the lattice formulation. It goes on to clarify the relationship between the resulting critical behavior due to symmetry breaking/restoration in QCD, before turning to the QCD phase diagram. The presentation of bulk equilibrium thermodyamics is completed by studying the properties of the quark-gluon plasma as a new state of strongly interacting matter. The final chapters of the book are devoted to more specific topics that arise when nuclear collisions are considered as a tool for the experimental study of QCD thermodynamics. This second edition includes a new chapter on the hydrodynamic evolution of the medium produced in nuclear collisions. Since the study of flow for strongly interacting fluids has gained ever-increasing importance over the years, it is dealt with it in some detail, including comments on gauge/gravity duality. Moreover, other aspects of experimental studies are brought up to date, such as the search for critical behavior in multihadron production, the calibration of quarkonium production in nuclear collisions, and the relation between strangeness suppression and deconfinement.
Extreme Survivors: Animals That Time Forgot (How Nature Works #0)
by Kimberly Ridley<p>Selected for the 2018 Bank Street College of Education Best STEM Children’s Books of the Year <p>What do the goblin shark, horseshoe crab, the “indestructible” water bear, and a handful of other bizarre animals have in common? <p>They are all “extreme survivors,” animals that still look much like their prehistoric ancestors from millions of years ago. <p>Meet ten amazing animals that appear to have changed little in more than 100 million years. They are the rare exceptions to the rule. <p>More than 99 percent of all life forms have gone extinct during the 3.6-billion-year history of life on Earth. Other organisms have changed dramatically, but not our extreme survivors. Evolution may have altered their physiology and behavior, but their body plans have stood the test of time. <p>How have these living links with Earth’s prehistoric past survived? The search for answers is leading scientists to new discoveries about the past—and future—of life on Earth. The survival secrets of some of these ancient creatures could lead to new medicines and treatments for disease. <p>Written in a lively, entertaining voice, Extreme Survivors provides detailed life histories and strange “survival secrets” of ten ancient animals and explains evolution and natural selection. Extensive back matter includes glossary, additional facts and geographic range for each organism and a geologic timeline of Earth. <p><B>F&P Level V </B> <P><P><i>Advisory: Bookshare has learned that this book offers only partial accessibility. We have kept it in the collection because it is useful for some of our members. To explore further access options with us, please contact us through the Book Quality link. Benetech is actively working on projects to improve accessibility issues such as these.</i>
Extreme Tissue Engineering
by Robert A. BrownHighly Commended at the BMA Book Awards 2013Extreme Tissue Engineering is an engaging introduction to Tissue Engineering and Regenerative Medicine (TERM), allowing the reader to understand, discern and place into context the mass of scientific, multi-disciplinary data currently flooding the field. It is designed to provide interdisciplinary, ground-up explanations in a digestible, entertaining way, creating a text which is relevant to all students of TERM regardless of their route into the field.Organised into three main sections: chapters 1 to 3 introduce and explain the general problems; chapters 4 to 6 identify and refine how the main factors interact to create the problems and opportunities we know all too well; chapters 7 to 9 argue us through the ways we can use leading-edge (extreme) concepts to build our advanced solutions.Students and researchers in areas such as stem cell and developmental biology, tissue repair, implantology and surgical sciences, biomaterials sciences and nanobiomedicine, bioengineering, bio-processing and monitoring technologies - from undergraduate and masters to doctoral and post-doctoral research levels - will find Extreme Tissue Engineering a stimulating and inspiring text.Written in a fluid, entertaining style, Extreme Tissue Engineering is introductory yet challenging, richly illustrated and truly interdisciplinary.
Extreme Tribology: Fundamentals and Challenges
by Ahmed AbdelbaryTribology is an unfamiliar term for many, but is experienced by all. It is the science of friction, wear and lubrication of contacting surfaces in relative motion. The aim of this book is to introduce the fundamentals of tribology as well as its challenges in extreme operating conditions. The book comprises a historical background and an introduction to familiarize both undergraduate and postgraduate readers with such an important topic. It addresses a comprehensive coverage of classical tribology of solid contacts, friction mechanics, wear mechanisms and lubrication technologies. The tribology of polymer composites, MEMS and NEMS are explored. In addition, tribology of automotive components is presented, as are tribological applications in many practical situations.Various test methods used in evaluating wear are reviewed. Diverse techniques applied in predicting wear behavior by mathematical models, FE modeling and ANN approach are discussed. The book reviews key features of extraordinary conditions associated with, but not limited to, harsh environments, severe sliding and poor lubrication challenges. A basic understanding of failure modes in tribological systems is covered. The state-of-the-art research on tribology under these extreme conditions is extensively discussed, which will be of interest to researchers. The book highlights solutions for extreme tribology problems and provides an overview of various factors affecting tribosystems in harsh conditions.
Extreme Waves
by Craig B. SmithWaves are hypnotic and beautiful. They can also be great fun. But Hurricanes Katrina and Rita taught us that they can be powerful and deadly while the 2004 tsunami proved that some waves are absolutely devastating. Science is the best tool for understanding and predicting the most extreme waves. Where do waves come from? Why are some big and some small? From winter to summer, the nature of the beach changes, sculpted by the tireless energy of waves. Most waves are simply rhythmic expressions of Earth's movement through space and the changes they bring to our shorelines are gradual. But given the right weather conditions and combination of natural forces, waves can wreak havoc. These are extreme waves, waves that can stretch 100-feet high--posing an imminent threat to large sea vessels and coastal structures. There are even waves that have stripped trees from mountains as they surged to an estimated 1,700 feet high. But even smaller waves are dangerous to ships and coastlines. Indeed, the lessons of the 2004 Bay of Bengal tsunami and the damage wrought by recent tidal surges in New Orleans underscore the need for better tracking and prediction of extreme waves. Extreme Waves is a fascinating history of waves. Covering both the headline stories as well as incidents that are less well-known but equally startling Craig Smith, author and amateur sailor, will have you riveted from the first chapter to the last.
Extreme Waves and Shock-Excited Processes in Structures and Space Objects: Volume II (Modeling of Extreme Waves in Technology and Nature)
by Shamil U. GalievThe theory of waves is generalized on cases when waves change medium in which they appear and propagate. A reaction of structural elements and space objects to the dynamic actions of the different nature, durations, and intensities is studied. It considers the effects of transitions in the state and phase equations of media on the formation and propagation of extreme waves as a result of power, thermal, or laser pulsed action. The influence of cavitation and cool boiling of liquids, geometric and physical nonlinearity of walls on containers’ strength, and the formation of extreme waves is studied. The theory can be also used to optimize impulse technology, in particular, in the optimization of explosive processing of sheet metal by explosion in a liquid. This book was written for researchers and engineers, as well as graduate students in the fields of thermal fluids, aerospace, nuclear engineering, and nonlinear waves.
Extreme Weather for Kids: Lessons and Activities All About Hurricanes, Tornadoes, Blizzards, and More!
by Matthew CappucciExtreme Weather for Kids is a whirlwind ride through the wild world of weather, written in accessible language and complemented by vivid descriptions and imagery. Designed to harness children’s natural curiosity, this action-packed introduction to meteorology incorporates first-hand accounts from inside Mother Nature’s most dramatic moments. For each phenomenon introduced, explanatory text, informative illustrations, sidebars, and asides allow readers to explore at their own pace. Along with storm-chasing reports and photos from in the field, each chapter includes a step-by-step hands-on activity for engaging with the science. What is the polar vortex? And why does a disrupted “polar vortex” lead to extreme cold air outbreaks across Europe, Asia, and North America? Among the many “in case you were wondering” questions addressed: - How strong can a hurricane get? - What’s the biggest tornado to have ever happened? - How large can hail get? - Is “thunders now” real? How does it form? - How thick is lightning? And how powerful is it? - Where can I find “fossilized lightning?” - Can it snow in the desert? - What are “solar storms?” - What makes the northern (and southern) lights? Weather is one of the most accessible sciences there is. Everyone experiences it in some way or another, and learning the basics behind it naturally sparks interest in other sciences. That’s why Extreme Weather for Kids also teaches the basic principles of scientific observation while placing a key emphasis on safety. Extreme Weather for Kids is sure to awaken the joy of learning rain or shine.
Extremes: Life, Death and the Limits of the Human Body
by Kevin FongIn anaesthetist Dr Kevin Fong's television programmes he has often demonstrated the impact of extremes on the human body by using his own body as a 'guinea pig'. So Dr Fong is well placed to share his experience of the sheer audacity of medical practice at extreme physiological limits, where human life is balanced on a knife edge. Through gripping accounts of extraordinary events and pioneering medicine, Dr Fong explores how our body responds when tested by the extremes of heat and cold, vacuum and altitude, age and disease. He shows how science, technology and medicine have taken what was once lethal in the world and made it survivable. This is not only a book about medicine, but also about exploration in its broadest sense - and about how, by probing the very limits of our biology, we may ultimately return with a better appreciation of how our bodies work, of what life is, and what it means to be human.
Extremes (Darwin College Lectures #31)
by Duncan Needham Julius WeitzdörferHumanity is confronted by and attracted to extremes. Extreme events shape our thinking, feeling, and actions; they echo in our politics, media, literature, and science. We often associate extremes with crises, disasters, and risks to be averted, yet extremes also have the potential to lead us towards new horizons. Featuring essays by leading intellectuals and public figures arising from the 2017 Darwin College Lectures, this volume explores 'extreme' events, from the election of President Trump, the rise of populism, and the Brexit referendum, to the 2008 financial crisis, the Syrian war, and climate change. It also celebrates 'extreme' achievements in the realms of health, exploration, and scientific discovery. A fascinating, engaging, and timely collection of essays by renowned scholars, journalists, and intellectuals, this volume challenges our understanding of what is normal and what is truly extreme, and sheds light on some of the issues facing humanity in the twenty-first century.
Extremes and Recurrence in Dynamical Systems
by Valerio Lucarini Ana De Freitas Jorge De Freitas Davide Faranda Mark Holland Matthew Nicol Mike Todd Sandro Vaienti Jeroen WoutersPresents recent advances on the theory of extreme values that result from investigations of dynamical systems applications Written by a team of international experts, Extremes and Recurrence in Dynamical Systems presents a unique point of view on the mathematical theory of extremes and how it relates to applications in the natural and social sciences. Featuring an interdisciplinary approach to new concepts in pure and applied mathematical research, the book skillfully combines the areas of statistical mechanics, probability theory, measure theory, dynamical systems, statistical inference, geophysics, and software application. Emphasizing statistical mechanics, the book introduces robust theoretical embedding for the application of extreme value theory and modeling through dynamical systems. Extremes and Recurrence in Dynamical Systems also features: A careful examination of how a dynamical system can be taken as a generator of stochastic processes Discussions on the applications of statistical inference in the theoretical and heuristic use of extremes Several examples of analysis of extremes in a physical and geophysical context A final summary of the main results presented with a discussion of forthcoming research guidelines An appendix with software Matlab® and Octave programming language to help readers to develop further understanding of the presented concepts Extremes and Recurrence in Dynamical Systems is ideal for academics and practitioners in pure and applied mathematics, probability theory, statistics, chaos, theoretical and applied dynamical systems, statistical mechanics, geophysical fluid dynamics, geosciences and complexity science.
Extremes in Atmospheric Processes and Phenomenon: Assessment, Impacts and Mitigation (Disaster Resilience and Green Growth)
by Pallavi Saxena Anuradha Shukla Anil Kumar GuptaThis edited book first gives an overview of issues in the studies of atmospheric sciences and then elaborates on extreme events in air pollution, their assessment, impacts, and mitigation strategies. It covers general overview of factors governing in atmosphere that lead to air pollution, description about recent and hazardous air pollution episodes, emergencies and extremes in atmospheric sciences, impact studies on living organisms and atmosphere related to emergencies and possible remedies/mitigation strategies which may also include green growth strategies for management. Increase in anthropogenic activities from different sources results in very high concentrations of air pollutants in the atmospheres and they lead to cause disturbance in seasonal cycles and atmospheric phenomena, ecological imbalance and change in the quality of air. These impacts are the major cause of short-term or long-term effects on living and non-living systems. In the recent years, several instances of extremes atmosphere and air pollution related emergencies causing accidental episodes, fog, smog, health related, heat and cold wave etc. are experienced. This book brings the attention on such issues in atmospheric sciences and discuss the disaster preparedness and management plus emergencies. This book is valuable reading material for students in Environmental Science, Biological Science, Medical Science, Policy Planning, Disaster Management and Agriculture. It’s useful for environmental consultants, researchers and other professionals involved in air quality, plant, humans and disasters related research.
Extremist Propaganda in Social Media: A Threat to Homeland Security
by Michael ErbschloeExtremist Propaganda in Social Media: A Threat to Homeland Security presents both an analysis of the impact of propaganda in social media and the rise of extremism in mass society from technological and social perspectives. The book identifies the current phenomenon, what shall be dubbed for purposes of this book "Blisstopian Societies"—characterized in the abiding "ignorance is bliss" principle—whereby a population is complacent and has unquestioning acceptance of a social doctrine without challenge and introspection. In these subcultures, the malleable population self-select social media content, "news," and propaganda delivery mechanisms. By doing so, they expose themselves only to content that motivates, reinforces, and contributes to their isolation, alienation, and self-regulation of the social groups and individuals. In doing this, objective news is dismissed, fake—or news otherwise intended to misinform—reinforces their stereotyped beliefs about society and the world around them. This phenomenon is, unfortunately, not "fake news," but a real threat to which counterterror, intelligence, Homeland Security, law enforcement, the military, and global organizations must be hyper-vigilant of, now and into the foreseeable future. Chapters cite numerous examples from the 2016 political election, the Russia investigation into the Trump Campaign, ISIS, domestic US terrorists, among many other examples of extremist and radicalizing rhetoric. The book illustrates throughout that this contrived and manufactured bliss has fueled the rise and perpetuation of hate crimes, radicalism, and violence in such groups as ISIS, Boko Haram, Neo-Nazis, white separatists, and white supremacists in the United States—in addition to perpetuating ethnic cleansing actions around the world. This dynamic has led to increased political polarization in the United States and abroad, while furthering an unwillingness and inability to both compromise or see others’ perspectives—further fomenting insular populations increasing willing to harm others and do violence. Extremist Propaganda in Social Media relates current Blisstopian practices to real-world hate speech and violence, connecting how such information is consumed by groups and translated into violent action. The book is an invaluable resources for those professionals that require an awareness of social media radicalization including: social media strategists, law enforcement, Homeland Security professionals, military planners and operatives—anyone tasked with countering combat such violent factions and fringes in conflict situations.
Extremophile Fishes
by Rüdiger Riesch Michael Tobler Martin PlathThis book summarizes the key adaptations enabling extremophile fishes to survive under harsh environmental conditions. It reviews the most recent research on acidic, Antarctic, cave, desert, hypersaline, hypoxic, temporary, and fast-flowing habitats, as well as naturally and anthropogenically toxic waters, while pointing out generalities that are evident across different study systems. Knowledge of the different adaptations that allow fish to cope with stressful environmental conditions furthers our understanding of basic physiological, ecological, and evolutionary principles. In several cases, evidence is provided for how the adaptation to extreme environments promotes the emergence of new species. Furthermore, a link is made to conservation biology, and how human activities have exacerbated existing extreme environments and created new ones. The book concludes with a discussion of major open questions in our understanding of the ecology and evolution of life in extreme environments.
Extremophile Mikroorganismen: Von Der Anpassung Zur Anwendung
by Andreas StolzDieses Buch gibt einen aktuellen Überblick über die Lebensräume und Lebensweisen extremophiler Mikroorganismen. In neun kompakten Kapiteln beleuchtet der Autor die Anpassungsfähigkeit extremophiler Mikroorganismen. Pro Kapitel wird wird ein extremer Lebensraum und seine Bewohner beschrieben und spannende Fragen beantwortet wie: Welche Typen lebensfeindlicher Gebiete auf der Erde können besiedelt werden? Welche Arten von Organismen sind hierzu befähigt? Welche Anpassungen haben sich entwickelt, damit diese Organismen in Umgebungen überleben können, die als lebensfeindlich gelten? Welche Hinweise gibt es zur Entstehung und Entwicklung der ersten Lebensformen in extremen Habitaten und kann man die Erkenntnisse über irdische Extremophile zur Abschätzung der Wahrscheinlichkeit außerirdischen Lebens nutzen? Dem Leser wird so ein Einstieg in dieses moderne Gebiet der Biologie ermöglicht. Der Autor zeigt in verschiedenen Beispielen unterschiedlichste Anwendungsmöglichkeiten extremophiler Organismen in der Biotechnologie auf. Hierbei reicht das Spektrum vom Einsatz der DNA-Polymerasen aus (hyper-)thermophilen Mikroorganismen für die Polymerase-Kettenreaktion, eine der wichtigsten Techniken der Biotechnologie, bis zum Einsatz acidophiler Mikroorganismen zur Gewinnung von Kupfer und Gold. Für Studierende und Wissenschaftler, die sich für die Vielfalt und Anpassungsfähigkeit von Mikroorganismen und deren Potenzial für die Biotechnologie und Industrie interessieren, ist dieses einführende Lehrbuch eine Bereicherung.
Extremophiles: General and Plant Biomass Based Biorefinery
by Pratibha DheeranThis book, Extremophiles: General and Plant Biomass Based Biorefinery, explores the potential of extremophiles in industries and biomass based biorefinery. The book sheds light on diversity and various applications of thermophiles, psychrophiles, halophiles, alkaliphiles and acidophiles for the production of value-added products including biofuels, extremozymes, etc. The chapters comprehensively emphasize the utility of extremophiles in sustainable biorefinery bioprocesses. This book is an integrated source of literature for scientists, engineers, academicians, and students working in the area of extremophiles, microbial technology and biorefinery.
Extremophiles: Wastewater and Algal Biorefinery
by Pratibha Dheeran Sachin KumarThis book ‘Extremophiles: Wastewater and Algal Biorefinery’ explores the potential of extremophiles/extremotolerant organisms in wastewater treatment, biorefining of algal biomass and in the treatment of industrial waste effluent. The book provides a holistic overview about the current status of extremophiles in waste water treatment and various industrial processes. The chapters comprehensively cover the scientific and research findings on various industrial applications of extremophiles such as biofuels, extremozymes, electricity generation, biofilms, microbial corrosion and waste water treatment etc. This book is an integrated source of literature for the scientists, engineers, academicians, and students working in the area of extremophiles, microbial technology and biorefinery.
Extremophiles: From Biology to Biotechnology
by Ravi V. Durvasula D. V. Subba RaoHighly recommended by CHOICE, Oct 2018 Key features: Couples studies of marine extremophile biology/genomics and extremophile culture for biotechnological applications with the latest advances in bio-prospecting and bio-product development Includes practical experiments that a laboratory can use to replicate extreme habitats for research purposes Presents latest advances in extremophile genomics to give the reader a better understanding of the regulatory mechanisms of extremophiles Offers insights into the production of commercially important extremozymes, carotenoids, bioactive compounds and secondary metabolites of medicinal value Extremophiles are nature’s ultimate survivors, thriving in environments ranging from the frozen Antarctic to abyssal hot hydrothermal vents. Their lifeforms span bacteria to fishes, and are categorized as halophiles from hypersaline environments, acidophiles from acidic waters, psychrophiles from cold habitats, and thermophiles from warm waters. Extremophiles: From Biology to Biotechnology comprehensively covers the basic biology, physiology, habitats, secondary metabolites for bioprospecting, and biotechnology of these extreme survivors. The chapters focus on the novel genetic and biochemical traits that lend these organisms to biotechnological applications. This unique guide serves as a resource for biotechnologists who wish to explore extremophiles for their commercial potential, as well as a valuable reference for teaching undergraduate, graduate and postgraduate students.
Extremophiles
by Om V. SinghExplores the utility and potential of extremophiles in sustainability and biotechnologyMany extremophilic bio-products are already used as life-saving drugs. Until recently, however, the difficulty of working with these microbes has discouraged efforts to develop extremophilic microbes as potential drug reservoirs of the future. Recent technological advances have opened the door to exploring these organisms anew as sources of products that might prove useful in clinical and environmental biotechnology and drug development.Extremophiles features outstanding articles by expert scientists who shed light on broad-ranging areas of progress in the development of smart therapeutics for multiple disease types and products for industrial use. It bridges technological gaps, focusing on critical aspects of extremolytes and the mechanisms regulating their biosynthesis that are relevant to human health and bioenergy, including value-added products of commercial significance as well as other potentially viable products.This groundbreaking guide:Introduces the variety of extremophiles and their extremolytes including extremozymesProvides an overview of the methodologies used to acquire extremophilesReviews the literature on the diversity of extremophilesOffers tools and criteria for data interpretation of various extremolytes/extremozymesDiscusses experimental design problems associated with extremophiles and their therapeutic implicationsExplores the challenges and possibilities of developing extremolytes for commercial purposesExplains the FDA's regulations on certain microbial bio-products that will be of interest to potential industrialistsExtremophiles is an immensely useful resource for graduate students and researchers in biotechnology, clinical biotechnology, microbiology, and applied microbiology.
EXTREMOPHILES as Astrobiological Models
by Joseph Seckbach Helga Stan-LotterThe data in this book are new or updated, and will serve also as Origin of Life and evolutionary studies. Endospores of bacteria have a long history of use as model organisms in astrobiology, including survival in extreme environments and interplanetary transfer of life. Numerous other bacteria as well as archaea, lichens, fungi, algae and tiny animals (tardigrades, or water bears) are now being investigated for their tolerance to extreme conditions in simulated or real space environments. Experimental results from exposure studies on the International Space Station and space probes for up to 1.5 years are presented and discussed. Suggestions for extaterrestrial energy sources are also indicated.