- Table View
- List View
ENZYMES: Catalysis, Kinetics and Mechanisms
by N. S. PunekarThis enzymology textbook for graduate and advanced undergraduate students covers the syllabi of most universities where this subject is regularly taught. It focuses on the synchrony between the two broad mechanistic facets of enzymology: the chemical and the kinetic, and also highlights the synergy between enzyme structure and mechanism. Designed for self-study, it explains how to plan enzyme experiments and subsequently analyze the data collected. The book is divided into five major sections: 1] Introduction to enzymes, 2] Practical aspects, 3] Kinetic Mechanisms, 4] Chemical Mechanisms, and 5] Enzymology Frontiers. Individual concepts are treated as stand-alone chapters; readers can explore any single concept with minimal cross-referencing to the rest of the book. Further, complex approaches requiring specialized techniques and involved experimentation (beyond the reach of an average laboratory) are covered in theory with suitable references to guide readers. The book provides students, researchers and academics in the broad area of biology with a sound theoretical and practical knowledge of enzymes. It also caters to those who do not have a practicing enzymologist to teach them the subject.
Enzymes and Drugs
by Serge Kirkiacharian Julien DumondEnzyme dysfunction, an essential catalyst for the smooth running of biochemical reactions and the maintenance of vital processes, is at the root of many pathologies that have paved the way for the development of numerous drugs. Aimed at pharmacists, biologists, biochemists, doctors, veterinarians, medicinal chemists and students from a wide range of disciplines, Enzymes and Drugs brings together, for the first time, extensive documentation highlighting the relationships between a large number of drugs and enzymes. The book also highlights new prospects for therapeutic discoveries offered by enzyme targeting. Numerous applications have been developed thanks to strategies for studying enzyme inhibition or activation, as well as the development of allosteric effectors, presented with their advantages and disadvantages. Various rare diseases, known as "orphan" diseases, have resulted from enzyme deficiency or absence. For their treatment, the introduction of substitute enzymes has led to major therapeutic advances.
Enzymes and Their Inhibitors: Drug Development
by H. John Smith Claire SimonsFocusing on the development of enzyme inhibitors as therapeutic drugs, Enzymes and Their Inhibitors: Drug Development provides a concise overview of the chemistry of major types of enzymes and their inhibitors. The opening chapters introduce readers to the structure, functions, mechanisms, and kinetics of enzymes, including their use as disease mar
ENZYMES: Catalysis, Kinetics and Mechanisms
by Narayan S. PunekarThe second edition of the textbook Enzymes- Catalysis, Kinetics, and Mechanisms focuses on the two broad mechanistic facets of enzymology namely, the chemical and the kinetic. It endeavors to bring out the synergy between enzyme structures and mechanisms. Written with a self-study approach in mind, the emphasis is on how to begin experiments with an enzyme and subsequently analyze the data. The book is divided into six major sections– 1) Enzyme Catalysis – A Perspective, 2) Enzyme Kinetic Practice and Measurements, 3) Elucidation of Kinetic Mechanisms, 4) Chemical Mechanisms and Catalysis, 5) Exploiting Enzymes, and 6) An end piece on Frontiers in Enzymology. The individual concepts are treated as stand-alone short sections. In case the reader needs to use any one concept, it should be possible with minimal cross-referencing to the rest of the book. Further, the book presents specialized techniques and complex approaches that require involved experimentation in theory with suitable references to guide the reader. The book is proposed more as a textbook in a self-learning mode to students of modern biology, particularly those with limited exposure to quantitative aspects and organic chemistry.
Enzymes for Pollutant Degradation (Microorganisms for Sustainability #30)
by Sikandar I. Mulla R. N. BharagavaThis book is about different Enzymes from various sources that play an important role in the degradation of an array of pollutants with simultaneous generation of value-added products.This is an “Edited Book” which deals a comprehensive knowledge on the role of different microorganisms/their enzymes in the degradation of pollutants, wastewater treatment with simultaneous production of value added products. It also deals the current state, perspectives and various challenges associated with the microbial/enzymatic degradation of environmental pollutants.This book will provide a profound knowledge on the importance of microorganisms/their enzymes in the degradation of pollutants like pesticides, antibiotics, toxic/hazardous chemicals, endocrine disrupting chemicals/compounds with production of value-added products like bioplastics for the sustainable development of society. It covers various existing wastewater treatment approaches using microorganisms alone and /or in combination of other methods with their merits, demerits and future prospects.
Enzymes for Solving Humankind's Problems: Natural and Artificial Systems in Health, Agriculture, Environment and Energy
by José J. G. Moura Isabel Moura Luisa B. MaiaThis book presents specific key natural and artificial systems that are promising biocatalysts in the areas of health, agriculture, environment and energy. It provides a comprehensive account of the state of the art of these systems and outlines the significant progress made in the last decade using these systems to develop innovative, sustainable and environmentally friendly solutions. Chapters from expert contributors explore how natural enzymes and artificial systems tackle specific targets such as: climate change, carbon footprint and economy and carbon dioxide utilisation; nitrogen footprint and fixation and nitrous oxide mitigation; hydrogen production, fuel cells and energy from bacteria; biomass transformation and production of added-value compounds, as well as biosensors development. This book provides an important and inspiring account for the designing of new natural and artificial systems with enhanced properties, and it appeals not only to students and researchers working in the fields of energy, health, food and environment, but also to a wider audience of educated readers that are interested in these up-to-date and exciting subjects.Chapter “Carbon Dioxide Utilisation—The Formate Route” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Enzymes in Degradation of the Lignocellulosic Wastes
by Aparna B. Gunjal Neha N. Patil Sonali S. ShindeThis book offers valuable insights into the principles, mechanisms of action and applications of traditional and novel enzymes involved in the degradation of wastes. Enzymes are biological catalysts that play an important role in various biochemical reactions. The generation of value-added products by means of these biological processes is also discussed. This book covers the use of in silico and computational methods in understanding the biodegradation processes, and reveals the importance of enzymes in various biochemical reactions and kinetics. The book’s target audience includes undergraduate and graduate students, faculty members at colleges and universities, research students, scientists and industry professionals.
Enzymes in Detergency (Surfactant Science)
by Jan H. van Ee Onno Misset Erik J. BaasOffers an integrated overview of enzyme use in household detergents, from product development and manufacturing to safety and health-related issues. The text details the major types of enzymes, structure-function relationships, life cycle analyses, protein-engineering techniques, cleaning mechanisms, and past, present and future applications.
Enzymes in Environmental Management (SpringerBriefs in Environmental Science)
by Javid Ahmad Parray Mohammad Yaseen Mir A. K. HaghiEnzymes can help break down plastic waste and make it less harmful to the environment. They can also be used to treat various types of waste, including agricultural and food waste, and wastewater. Enzyme engineering is an important part of chemical biotechnology and helps to keep the environment clean. Making clean and renewable fuels is a priority, and many strategies are being developed to achieve this goal. However, food waste is still a major problem that can harm the environment because most disposal methods are not eco-friendly. This volume aims to inform readers about the latest developments in the use of enzymes for environmental management. This comprehensive resource provides a detailed overview of how enzymes can be used in various sectors to promote ecological sustainability. It covers the composition, properties, characterization, chemistry, and applications of different enzymes in emerging and eco-friendly approaches to waste treatment. It also highlights the latest advancements in sustainable technology and biotechnology enzymes. The book is divided into sections that feature various enzymes used for treating resistant pollutants in wastewater, enzymatically degrading synthetic plastics, and engineering enzymes to impact environmental sustainability positively. It also covers enzymes used in the valorization of waste, enzyme technology in biofuel production, and the recovery of enzymes from food waste. Each chapter presents the enzymes' chemical, physical, and biological attributes and reviews the recent research conducted in this emerging field. The authors hope this document will inspire scientists to explore novel chemical, material, and energy sources in the future and to continue developing innovative applications for enzymes in environmental management.
Enzymes in Food Technology: Improvements and Innovations
by Mohammed KuddusThe integration of enzymes in food processing is well known, and dedicated research is continually being pursued to address the global food crisis. This book provides a broad, up-to-date overview of the enzymes used in food technology. It discusses microbial, plant and animal enzymes in the context of their applications in the food sector; process of immobilization; thermal and operational stability; increased product specificity and specific activity; enzyme engineering; implementation of high-throughput techniques; screening of relatively unexplored environments; and development of more efficient enzymes. Offering a comprehensive reference resource on the most progressive field of food technology, this book is of interest to professionals, scientists and academics in the food and biotech industries.
Enzymes in Neurodegenerative Disorders: Mechanism and Therapeutic Potentials
by Bijo Mathew Della Grace Thomas ParambiThis book delves into the correlation between different enzymes and neurodegenerative disorders. It investigates the intricate processes that contribute to the decline of cognitive functions, memory impairment, and other incapacitating symptoms of Alzheimer's disease. The book examines the roles of diverse enzymes in Amyotrophic Lateral Sclerosis and their effects on the motor neurons, leading to muscle weakness, paralysis, and eventual fatality. Moreover, it examines the association between depression and the enzymes responsible, providing a fresh viewpoint on the biochemical foundation of this ailment. Lastly, the book explores the connection between enzymes and Parkinson's disease, discussing the mechanisms that cause the death of dopamine-producing neurons and the related symptoms. By examining the functions of various enzymes in Parkinson's disease, the book presents a distinct outlook on the intricate interplay between enzymes and several neurological conditions, imparting readers with a comprehensive understanding of the fundamental mechanisms that underlie these disorders.
Enzymes in Nonaqueous Solvents
by Evgeny N. VulfsonIn Enzymes in Nonaqueous Solvents: Methods and Protocols, leading chemists, biochemists, biotechnologists, and process engineers summarize for the first time a wide range of methods for executing enzymatic transformations under nonaqueous conditions. Each method includes detailed step-by-step instructions for its successful completion, a list of materials, and ancillary notes that explain the scientific basis of the procedure, as well as troubleshooting. Also provided are a generic description of key reactions, advice on biocatalyst preparation, discussion of reaction conditions, and instructions on bioreactor design. Comprehensive and state-of-the-art, Enzymes in Nonaqueous Solvents: Methods and Protocols offers today's synthetic chemists, biochemists, and process engineers all the essential information needed to carry out enzymatic reactions in nonaqueous media, as well as to successfully scale up to production quantities.
Enzymes in Textile Processing: Textile Industry, Enzymes, and SDGs (SDGs and Textiles)
by Muhammad ArshadThe book offers a comprehensive overview of low-capital cost technologies for enzyme manufacture and utilization in the textile industry with sustainable bioenergy from effluent. Enzymes produced from renewable sources to replace potentially harmful chemicals in textile products have been outlined in making the textile industry greener and eco-friendly. The current book also addresses the strategies to achieve sustainable development goals (SDGs) and sustainability education in the textile sector. In particular, the use of green enzymes to convert by-products from textile effluents into bioenergy has been highlighted. This book outfits academic researchers, industrial practitioners, and policymakers for the engagement of green enzymes as a step toward sustainable development goals in the textile industry.
Enzymes in the Environment: Activity, Ecology, and Applications (Books In Soils, Plants, And The Environment Ser. #Vol. 86)
by Richard G. Burns Richard P. DickThe need to understand the biological processes that are important for essential aquatic and terrestrial ecosystem function has prompted much research into the field of ecological enzymology. This book presents the two broad areas of application in a compilation of reviews by 21 international experts in their respective fields. The first explores e
Enzymes in the Valorization of Waste: Enzymatic Hydrolysis of Waste for Development of Value-added Products (Novel Biotechnological Applications for Waste to Value Conversion)
by Pradeep VermaEnzymes play a vital role in the enzymatic hydrolysis of waste for its conversion to useful value-added products. Enzymatic Hydrolysis of Waste for Development of Value-added Products focusses on the role of key enzymes such as cellulase, hemicellulases, amylases, and auxiliary enzymes (LMPOs), used in the hydrolysis step of the biorefinery setup. Further, it discusses the role of enzymes in the generation of reducing sugars and value-added compounds, with major emphasis on recent advances in the field. The mechanism, importance, type, evolution, and role of enzymes in hydrolysis constitute the crux of this volume, which is illustrated with examples and pertinent case studies. Features: • Explores the role of hydrolyzing enzymes in the breakdown and transformation of biomass hydrolysis. • Discusses the potential of auxiliary enzymes (LPMOs) for enhancing hydrolysis potential. • Covers recent developments in the field of enzymatic-assisted hydrolysis of waste for conversion of waste to value-added products. • Deliberates all possible products that can be generated from enzymatic hydrolysis of waste and their potential utilization. • Elucidates the limitations and advantages of enzyme-based hydrolysis and possible strategies for moving from the laboratory to large scale industries. This book is aimed at graduate students, researchers and related industry professionals in biochemical engineering, environmental science, wastewater treatment, biotechnology, applied microbiology, biomass-based biorefinery, biochemistry, green chemistry, sustainable development, waste treatment, enzymology, microbial biotechnology, and waste valorization.
Enzymes in the Valorization of Waste: Enzymatic Pretreatment of Waste for Development of Enzyme-based Biorefinery (Novel Biotechnological Applications for Waste to Value Conversion)
by Pradeep Verma"Enzymes in Valorization of waste: Enzymatic pre-treatment of waste for development of enzyme based biorefinery" focusses on the role of key delignifying enzymes (Laccase, MnP, LiP and LPMO’s) involved in biomass pre-treatment. The role of these enzymes such as hemicellulose, chitinases, and pectinases are discussed exhaustively including enzyme assisted recovery of high value phenolic compounds and value-added compounds generated during the pre-treatment process. All chapters cover broad topics and thematic areas associated with the pre-treatment step of biorefinery including enzyme mediated water treatment and its associated applications in biofuels, biorefineries and bioconversion. Features: Highlights mechanistic approach how the enzyme being able to regulate the delignification. Discusses advantages of the enzymatic delignification over other physical and chemical methods. Illustrates role of enzymes such as pectinase and chitinases and breaking down of biomass recalcitrance due to presence of pectin and chitin. Consolidates details on de-lignifying enzymes ((Laccase, MnP, LiP and LPMO’s) suitable in biomass pretreatment. Explores role of delignifying enzymes in high value phenolic compounds recovery during the enzymatic delignification. This book aims at Graduate students, Researchers and related Industry Professionals in Biochemical Engineering, Environmental Science, Wastewater Treatment, Biotechnology, Applied Microbiology, Biomass Based Biorefinery, Biochemistry, Green Chemistry, Sustainable Development, Waste Treatment, Enzymology, Microbial Biotechnology, and Waste Valorization.
Enzymes in the Valorization of Waste: Next-Gen Technological Advances for Sustainable Development of Enzyme based Biorefinery (Novel Biotechnological Applications for Waste to Value Conversion)
by Pradeep VermaEnzymes in the Valorization of Waste: Next-Gen Technological Advances for Sustainable Development of Enzyme-based Biorefinery focusses on key enzymes which are involved in the development of integrated biorefinery. It highlights the modern next-gen technologies for promoting the application of sustainable and greener enzymatic steps at industrial scale for the development of futuristic and self-sustainable "consolidated/integrated biorefinery/enzyme-based biorefinery." It also deals with technological advancement for improvement of enzyme yield or specificity, conversion capability, such as protein and metabolic engineering and advances in next generation technologies, and so forth. Features: • Explores all modern-day technologies that can potentially be used in enzyme-based biorefinery conversion of wastes to value-added products. • Covers technological, economic, and environmental assessments of enzyme-based biorefinery prospects. • Deliberates all possible products that can be generated from wastes including biofuel and essential chemicals. • Illustrates techniques for enhanced yield and properties to be used in various industrial applications. • Reviews advanced information of relevant sources and mechanism of enzymes. This book is aimed at graduate students, researchers and related industry professionals in biochemical engineering, environmental science, wastewater treatment, biotechnology, applied microbiology, biomass-based biorefinery, biochemistry, green chemistry, sustainable development, waste treatment, enzymology, microbial biotechnology, and waste valorization.
Enzymes of Molecular Biology
by Michael M. BurrellProvides key information on a wide range of enzymes commonly used as tools in molecular biology, helping to minimize the time a scientist spends researching the literature to get reactions to work efficiently and allowing the nonenzymologist to design an experiment. Each chapter gives background information on the enzyme selected and those parameters important in its use, describes both the source and application of the enzyme, and provides details on the size and structure of the protein. Specific parameters essential for achieving an optimized reaction are discussed, along with exemplary practical procedures an protocols.
Enzymes of Nucleic Acid Synthesis and Modification: Volume 2: RNA Enzymes
by Samson T. JacobThe First volume gives an overview of the enzymes involved in DNA synthesis and modification; the second volume deals with the RNA-enzymes. Although the major emphasis of the book is on eukaryotic enzymes, a separate chapter dealing with prokaryotic DNA repair enzymes has been included to discuss the major advances in this field in recent years. There are two separate chapters on RNA polymerases to provide a comprehensive coverage of the enzymes from lower eukaryotes, plants and higher eukaryotes.
Enzymes of Nucleic Acid Synthesis and Modification: Volume 1: DNA Enzymes
by Samson T. JacobThe First volume gives an overview of the enzymes involved in DNA synthesis and modification; the second volume deals with the RNA-enzymes. Although the major emphasis of the book is on eukaryotic enzymes, a separate chapter dealing with prokaryotic DNA repair enzymes has been included to discuss the major advances in this field in recent years. There are two separate chapters on RNA polymerases to provide a comprehensive coverage of the enzymes from lower eukaryotes, plants and higher eukaryotes.
Enzymology of Complex Alpha-Glucans
by Felix NitschkeGlycogen and Starch: So Similar, yet so Different. Both carbohydrates are central to the primary metabolism of a large part of the living kingdom. Generally, animals, fungi, and bacteria store glycogen, while plants largely rely on starch. This book provides a broad and current view on both glycogen and starch, in lower and higher organisms. Beside biochemistry, physiology and regulation of glycogen and starch metabolism, the reader can expect an insight into glycogen storage diseases, select methods and relevant techniques. While significant progress has been made in both fields, this volume emphasizes an opportunity of collaboration for researchers working on a major intersection of the living world.
Eosinophils: Methods and Protocols (Methods in Molecular Biology #2241)
by Garry M. WalshThis second edition of Eosinophils: Methods and Protocols updates several techniques from the first edition together with novel in vitro and in vivo-based methodologies. Written by internationally recognized expert authorities, this volume provides vital techniques from eosinophil purification to experimental modelling, with each technique spelled out in clear and straightforward terms, assuming no previous knowledge of the method and without necessitating sourcing additional information elsewhere. Written in the highly successful Methods in Molecular Biology format, chapters include introductions to their respective topics, lists of the essential materials and reagents, step-by-step, readily reproducible laboratory protocols, with tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Eosinophils: Methods and Protocols, Second Edition provides the practical means to extend our knowledge of eosinophil function in health and disease, underpinning research that may in turn lead to new hypotheses for future examinations into the role of this intriguing and enigmatic leukocyte.
EPA Environmental Engineering Sourcebook
by J. Russell BouldingThe U.S. Environmental Protection Agency (U.S. EPA) publishes several series of documents that provide up-to-date information about environmental site assessment and remediation. The EPA Environmental Engineering Sourcebook includes papers and bulletins that focus on remediation of soil and groundwater, making them available in a convenient form.This book compiles thirty-five documents- written by recognized leaders - on major methods and promising new techniques for hazardous waste treatment and site remediation. Each chapter evaluates the type of contaminant and site characteristics needed to select a technology for use at hazardous waste sites.The EPA Environmental Engineering Sourcebook presents EPA documents in an easy-to-use, concise format. It contains numerous graphs, charts and figures that make it an important resource for those involved in environmental protection, site remediation, and site assessment. FeaturesContains chapters written by recognized leadersExamines major methods as well as assesses new techniques for hazardous waste treatment and site remediationPresents information in an easy-to-use, concise formatEvaluates each type of contaminant and site characteristics for selecting technology at hazardous waste sites
EPFL Lectures on Conformal Field Theory in D ≥ 3 Dimensions
by Slava RychkovThis primer develops Conformal Field Theory (CFT) from scratch, whereby CFT is viewed as any conformally-invariant theory that describes a fixed point of a renormalization group flow in quantum field theory. The book is divided into four lectures: Lecture 1 addresses the physical foundations of conformal invariance, while Lecture 2 examines the constraints imposed by conformal symmetry on the correlation functions of local operators, presented using the so-called projective null cone - a procedure also known as the embedding formalism. In turn, Lecture 3 focuses on the radial quantization and the operator product expansion, while Lecture 4 offers a very brief introduction to the conformal bootstrap. Derived from course-based notes, these lectures are intended as a first point of entry to this topic for Master and PhD students alike.
Ephemeridenrechnung Schritt für Schritt: Sonnenaufgang und Co. bestimmen leicht gemacht
by Dieter RichterDas vorliegende Buch vermittelt die Grundkenntnisse der Ephemeridenrechnung. Ausgehend von den Kepler’schen Gesetzen erfolgt die Berechnung der Koordinaten der Planeten in der Bahnebene. Über eine Anzahl von Transformationen ermittelt man die Koordinaten im Horizontsystem und erhält damit die Winkel, die an einem Teleskop einzustellen sind, um einen bestimmten Planeten zu sehen. Dabei werden das Zweikörper- oder Kepler-Problem und die Berechnung weiterer Parameter, wie die Bahngeschwindigkeit und der Abstand der Planeten von der Sonne, geschlossen hergeleitet, ausführlich erklärt und am Beispiel einzelner Planeten vorgerechnet. Ergänzend dazu, und über das Zweikörperproblem hinausgehend, wird die Berechnung der Mondposition erläutert.Außerdem werden die wichtigsten Einflüsse auf die Planetenbahnen, die im Rahmen der Berechnung als Zweikörperproblem nicht berücksichtigt wurden, erklärt und deren Wirkung auf die Planeten abgeschätzt. Zum besseren Verständnis ist eine Reihe von Beispielen beschrieben und vorgerechnet, bei denen die erworbenen Kenntnisse angewendet werden.Das Buch wendet sich an Studierende der Naturwissenschaften, Physik, Astronomie und an Amateurastronomen sowie naturwissenschaftlich Interessierte, die schon immer einmal erfahren wollten, woher man denn weiß, wann die Sonne aufgeht..