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Fractured Rock Hydraulics
by Fernando Olavo FrancissUniquely devoted to hard and fractured rock hydraulics, this advanced-level introduction provides tools to solve practical engineering problems. Chapter I covers the fundamentals of fractured rock hydraulics under a tensor approach. Chapter II presents some key concepts about approximate solutions. Chapter III discuss a few data analysis techniques
Fractured Rock Hydrogeology (ISSN)
by John M. SharpUnderstanding of groundwater flow and solute transport in fractured rocks is vital for analysis of water resources, water quality and environmental protection, geotechnical and engineering projects, and geothermal energy production. This book includes theoretical and practical analyses using numerical modelling, geochemistry, isotopes, aquifer tests, laboratory tests, field mapping, geophysics, geological analyses, and some unique combinations of these types of investigation. Current water resource and geotechnical problems and the techniques now used are also discussed. Aimed at practicing hydrogeologists, engineers, ecologists, resource managers, students and earth scientists.
Fractured Tide
by Leslie LutzLost meets Stranger Things in this eerie, immersive YA thriller, thrusting seventeen-year-old Sia into a reality where the waters in front of her and the jungle behind her are as dangerous as the survivors alongside her. Sia practically grew up in the water scuba diving, and wreck dives are run of the mill. Take the tourists out. Explore the reef. Uncover the secrets locked in the sunken craft. But this time … the dive goes terribly wrong.Attacked by a mysterious creature, Sia&’s boat is sunk, her customers are killed, and she washes up on a deserted island with no sign of rescue in sight. Waiting in the water is a seemingly unstoppable monster that is still hungry. In the jungle just off the beach are dangers best left untested. When Sia reunites with a handful of survivors, she sees it as the first sign of light.Sia is wrong.Between the gulf of deadly seawater in front of her and suffocating depth of the jungle behind her, even the island isn&’t what it seems.Haunted by her own mistakes and an inescapable dread, Sia&’s best hope for finding answers may rest in the center of the island, at the bottom of a flooded sinkhole that only she has the skills to navigate. But even if the creature lurking in the depths doesn&’t swallow her and the other survivors, the secrets of their fractured reality on the island might.Fractured Tide:Is and eerie and immersive YA thriller told through journal entries from a daughter to her fatherUnfolds through the eyes of a narrator who keeps you guessing until the final pagesIs a gripping mix of suspense and horror; perfect for readers ages 13 and up
Fractured: Book Two in the Slated Trilogy (Slated #2)
by Teri TerryPerfect for fans of the dystopian settings of The Hunger Games and Divergent, the gripping second installment of the Slated trilogy is a riveting psychological thriller set in a future where violent teens have their memory erased as an alternative to jail. Kyla has been Slated—her personality wiped blank, her memories lost to her forever. Or so she thought. She shouldn’t be able to remember anything. But increasingly she can—and she’s discovering that there are a lot of dark secrets locked away in her memories. When a mysterious man from her past comes back into her life and wants her help, she thinks she’s on her way to finding the truth. But this new knowledge lands her in the middle of a tug-of-war between two dangerous adversaries, and despite her misgivings about both of them, she’s forced to choose a side for her own protection.
Fragile Beginnings
by Adam WolfbergThis is a gripping medical narrative that brings readers into the complex world of newborn intensive care, where brilliant but imperfect doctors do all they can to coax life into their tiny, injured patients. Dr. Adam Wolfberg--journalist, physician specializing in high-risk pregnancies, and father to a child born weighing under two pounds--describes his daughter Larissa's precipitous birth at six months, which left her tenuously hanging on to life in an incubator. Ultrasound had diagnosed a devastating hemorrhage in her brain that doctors reasoned would give her only a 50 percent chance of having a normal IQ. As they make decisions about live-saving care in the first hours of a premature infant's life, doctors and parents must grapple with profound ethical and scientific questions: Who should be saved? How aggressively should doctors try to salvage the life of a premature baby, who may be severely neurologically and physically impaired? What will that child's quality of life be like after millions of dollars are spent saving him or her? Wolfberg explores the fits and starts of physicians, government policy makers, and lawyers who have struggled over the years to figure out the best way to make these wrenching decisions. Through Larissa's early hospital course and the struggle to decide what is best for her, Wolfberg examines the limitations of newborn intensive-care medicine, neuroplasticity, and decision making at the beginning of life. Featuring high-profile scientific topics and explanatory medical reporting, this is the first book to explore the profound emotional and ethical issues raised by advancing technology that allows us to save the lives of increasingly undeveloped preemies.
Fragment-Based Drug Discovery and X-Ray Crystallography
by Thomas G. Davies Marko HyvönenIntroduction to Fragment-Based Drug Discovery, by Daniel A. Erlanson Fragment Screening Using X-Ray Crystallography, by Thomas G. Davies and Ian J. Tickle Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening, by Stephen Roughley, Lisa Wright, Paul Brough, Andrew Massey and Roderick E. Hubbard Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors, by Daniel F. Wyss, Yu-Sen Wang, Hugh L. Eaton, Corey Strickland, Johannes H. Voigt, Zhaoning Zhu and Andrew W. Stamford Combining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery, by Michael Hennig, Armin Ruf and Walter Huber Targeting Protein-Protein Interactions and Fragment-Based Drug Discovery, by Eugene Valkov, Tim Sharpe, May Marsh, Sandra Greive and Marko Hyvönen Fragment Screening and HIV Therapeutics, by Joseph D. Bauman, Disha Patel and Eddy Arnold Fragment-Based Approaches and Computer-Aided Drug Discovery, by Didier Rognan
Fragmentation Processes: Topics in Atomic and Molecular Physics
by Colm T. WhelanRevolutionary advances in experimental techniques and spectacular increases in computer power over recent years have enabled researchers to develop a much more profound understanding of the atomic few-body problem. One area of intense focus has been the study of fragmentation processes. Covering the latest research in the field, this edited text is the first to provide a focussed and systematic treatment of fragmentation processes, bringing together contributions from a range of leading experts. As well as tackling the more established electron-impact ionization processes, (e,2e), this book also guides the reader through topics such as molecular fragmentation, ion-atom collisions and multi-photon processes. Combining a broad range of topics with an equal mix of theoretical and experimental discussion, this is an invaluable text for graduate students and researchers in atomic collisions, laser physics and chemistry.
Fragmentation: Toward Accurate Calculations on Complex Molecular Systems
by Mark S. GordonFragmentation: Toward Accurate Calculations on Complex Molecular Systems introduces the reader to the broad array of fragmentation and embedding methods that are currently available or under development to facilitate accurate calculations on large, complex systems such as proteins, polymers, liquids and nanoparticles. These methods work by subdividing a system into subunits, called fragments or subsystems or domains. Calculations are performed on each fragment and then the results are combined to predict properties for the whole system. Topics covered include: Fragmentation methods Embedding methods Explicitly correlated local electron correlation methods Fragment molecular orbital method Methods for treating large molecules This book is aimed at academic researchers who are interested in computational chemistry, computational biology, computational materials science and related fields, as well as graduate students in these fields.
Fragments of Fullerenes and Carbon Nanotubes
by Harold W. Kroto Lawrence T. Scott Marina A. PetrukhinaThis book is the first of its kind to reflect upon the intense and rapidly growing interest in open geodesic polyaromatic molecules, specifically focusing on their synthesis and reactivity in metal binding reactions. The book broadly covers all aspects related to the fullerene fragment chemistry: current synthetic techniques, description of the available members of this new family (which has grown to more than two dozens members, with none being available commercially), molecular geometry and trends in the solid state packing, as well as extensions into physical properties and new buckybowl-based molecules and materials. It covers fundamental research related to a new class of hydrocarbons, namely open geodesic polyarenes that map onto the surfaces of fullerenes (and referred to as fullerene fragments or buckybowls.
Fragrances in the Environment (The Handbook of Environmental Chemistry #128)
by Vera Homem Nuno RatolaThis book offers a comprehensive and authoritative review of the key environmental areas and compartments where fragrances have been found and discusses the current challenges of their presence and potential hazards. The book starts with a chapter devoted to the manufacturing and characterization of the most relevant types of fragrances, and their emissions to the environment. Subsequent chapters cover topics such as fragrances’ toxic effects on the environment, their major routes of exposure, behaviour, and fate in different environmental matrices. Particular attention is given to ecotoxicological issues and the environmental impact of fragrances in wastewater treatment plants, surface waters, marine environments, soils, remote areas, and air. In this book, readers will find valuable insights into the bioaccessibility and availability of synthetic musks in seafood and the corresponding human exposure and health risks. The book also outlines the most promising analytical methods used for fragrance detection and quantification, and it discusses the risks and future trends in this field. Written by a multidisciplinary team of expert contributors, and considering its scope, this book is an essential tool not only for scholars and researchers in academia and industry but also for other stakeholders and decision-makers interested in the field of fragrances and their ecotoxicology, as well as environmental impacts.
Fragrant
by Mandy AftelThe "Alice Waters of American natural perfume" (indieperfume.com) celebrates our most potent sense, through five rock stars of the fragrant world. Mandy Aftel is widely acclaimed as a trailblazer in natural perfumery. Over two decades of sourcing the finest aromatic ingredients from all over the world and creating artisanal fragrances, she has been an evangelist for the transformative power of scent. In Fragrant, through five major players in the epic of aroma, she explores the profound connection between our sense of smell and the appetites that move us, give us pleasure, make us fully alive. Cinnamon, queen of the Spice Route, touches our hunger for the unknown, the exotic, the luxurious. Mint, homegrown the world over, speaks to our affinity for the familiar, the native, the authentic. Frankincense, an ancient incense ingredient, taps into our longing for transcendence, while ambergris embodies our unquenchable curiosity. And exquisite jasmine exemplifies our yearning for beauty, both evanescent and enduring. In addition to providing a riveting initiation into the history, natural history, and philosophy of scent, Fragrant imparts the essentials of scent literacy and includes recipes for easy-to-make fragrances and edible, drinkable, and useful concoctions that reveal the imaginative possibilities of creating with--and reveling in--aroma. Vintage line drawings make for a volume that will be a treasured gift as well as a great read.
Frailty and Cardiovascular Diseases: Research into an Elderly Population (Advances in Experimental Medicine and Biology #1216)
by Nicola VeroneseThis book aims to clarify the potential association between frailty and cardiovascular disease in older people. Covering the biological as well as the clinical point of view, it allows researchers and clinicians to discover the significance of this topic. The contributions cover the most important aspects in the potential relationship between frailty and cardiovascular disease. In particular, authoritative authors in this field have clarified the definition and the epidemiology of frailty and cardiovascular disease in older people. A large part of the volume is dedicated to the biological mechanisms of frailty and cardiovascular disease, trying to find those in common between these two conditions. Since this book is dedicated to both researchers and clinicians, we have proposed some chapters to the importance of comprehensive geriatric assessment in the evaluation and treatment of cardiovascular diseases and frailty. In this regard, the importance of geriatric evaluation in cardiac surgery for older people is well covered. Finally, the importance of cardiac rehabilitation and physical exercise is summarized, being, actually, the most important treatments for both frailty and cardiovascular disease. Written by many well-known and widely published experts in their respective fields, this book will appeal to a wide readership such as researchers in the field and clinicians, especially suited in geriatric medicine and cardiology who, every day, face frail older patients.
Frame Theory in Data Science (Advances in Science, Technology & Innovation)
by Zhihua Zhang Palle E. JorgensenThis book establishes brand-new frame theory and technical implementation in data science, with a special focus on spatial-scale feature extraction, network dynamics, object-oriented analysis, data-driven environmental prediction, and climate diagnosis. Given that data science is unanimously recognized as a core driver for achieving Sustainable Development Goals of the United Nations, these frame techniques bring fundamental changes to multi-channel data mining systems and support the development of digital Earth platforms. This book integrates the authors' frame research in the past twenty years and provides cutting-edge techniques and depth for scientists, professionals, and graduate students in data science, applied mathematics, environmental science, and geoscience.
Frames of Meaning: The Social Construction of Extraordinary Science (Routledge Library Editions: History & Philosophy of Science)
by H M Collins & PinchOriginally published in 1982. Taking a radical interpretation of the Kuhnian concept of paradigm incommensurability, the authors begin by discussing the difficulties of gaining access to the ideas of communities with different rational categories, and then define the subject area of parapsychology, offering a review of the relevant literature. After exploring parapsychology’s compatibility with science, physics, psychology and quantum theory, the authors move on from this predominantly theoretical framework, and devote the middle section to an empirical study of metal bending. They conclude with an examination of the results, analyse diverse interpretations and investigate the consequences for the idea of scientific revolution.
Framing Animals as Epidemic Villains: Histories of Non-Human Disease Vectors (Medicine and Biomedical Sciences in Modern History)
by Christos LynterisThis book takes a historical and anthropological approach to understanding how non-human hosts and vectors of diseases are understood, at a time when emerging infectious diseases are one of the central concerns of global health. The volume critically examines the ways in which animals have come to be framed as ‘epidemic villains’ since the turn of the nineteenth century. Providing epistemological and social histories of non-human epidemic blame, as well as ethnographic perspectives on its recent manifestations, the essays explore this cornerstone of modern epidemiology and public health alongside its continuing importance in today’s world. Covering diverse regions, the book argues that framing animals as spreaders and reservoirs of infectious diseases – from plague to rabies to Ebola – is an integral aspect not only to scientific breakthroughs but also to the ideological and biopolitical apparatus of modern medicine. As the first book to consider the impact of the image of non-human disease hosts and vectors on medicine and public health, it offers a major contribution to our understanding of human-animal interaction under the shadow of global epidemic threat.
Framing in Sustainability Science: Theoretical and Practical Approaches (Science for Sustainable Societies)
by Takashi Mino Shogo KudoThis open access book offers both conceptual and empirical descriptions of how to “frame” sustainability challenges. It defines “framing” in the context of sustainability science as the process of identifying subjects, setting boundaries, and defining problems. The chapters are grouped into two sections: a conceptual section and a case section. The conceptual section introduces readers to theories and concepts that can be used to achieve multiple understandings of sustainability; in turn, the case section highlights different ways of comprehending sustainability for researchers, practitioners, and other stakeholders. The book offers diverse illustrations of what sustainability concepts entail, both conceptually and empirically, and will help readers become aware of the implicit framings in sustainability-related discourses. In the extant literature, sustainability challenges such as climate change, sustainable development, and rapid urbanization have largely been treated as “pre-set,” fixed topics, while possible solutions have been discussed intensively. In contrast, this book examines the framings applied to the sustainability challenges themselves, and illustrates the road that led us to the current sustainability discourse.
Fran the Fire Ant
by Chris Jones Danny ResnerFran is a fire ant with a very important job—she’s a nurse ant! When the nest’s queen lays eggs, it’s the nurse ants’ job to raise the eggs into larvae and pupae so they grow up to become healthy worker ants to help build and run the nest.
Francis Bacon
by Perez ZagorinFrancis Bacon (1561-1626), commonly regarded as one of the founders of the Scientific Revolution, exerted a powerful influence on the intellectual development of the modern world. He also led a remarkably varied and dramatic life as a philosopher, writer, lawyer, courtier, and statesman. Although there has been much recent scholarship on individual aspects of Bacon's career, Perez Zagorin's is the first work in many years to present a comprehensive account of the entire sweep of his thought and its enduring influence. Combining keen scholarly and psychological insights, Zagorin reveals Bacon as a man of genius, deep paradoxes, and pronounced flaws. The book begins by sketching Bacon's complex personality and troubled public career. Zagorin shows that, despite his idealistic philosophy and rare intellectual gifts, Bacon's political life was marked by continual careerism in his efforts to achieve advancement. He follows Bacon's rise at court and describes his removal from his office as England's highest judge for taking bribes. Zagorin then examines Bacon's philosophy and theory of science in connection with his project for the promotion of scientific progress, which he called "The Great Instauration." He shows how Bacon's critical empiricism and attempt to develop a new method of discovery made a seminal contribution to the growth of science. He demonstrates Bacon's historic importance as a prophetic thinker, who, at the edge of the modern era, predicted that science would be used to prolong life, cure diseases, invent new materials, and create new weapons of destruction. Finally, the book examines Bacon's writings on such subjects as morals, politics, language, rhetoric, law, and history. Zagorin shows that Bacon was one of the great legal theorists of his day, an influential philosopher of language, and a penetrating historian. Clearly and beautifully written, the book brings out the richness, scope, and greatness of Bacon's work and draws together the many, colorful threads of an extraordinarily brilliant and many-sided mind.
Francis Bacon: De La Magia A La Ciencia (Routledge Library Editions: History & Philosophy of Science #Vol. 606)
by Paolo RossiOriginally published in 1968. This volume discusses Francis Bacon’s thought and work in the context of the European cultural environment that influenced Bacon’s philosophy and was in turn influenced by it. It examines the influence of magical and alchemical traditions on Bacon and his opposition to these traditions, as well as illustrating the naturalist, materialist and ethico-political patterns in Bacon’s allegorical interpretations of fables.
Francis Bacon’s Skeptical Recipes for New Knowledge
by Jagdish HattiangadiThe book sets an ambitious goal. It devises a new account of scientific methodology that makes it possible to explain how scientists manage, at least occasionally, to find true models of reality. The new methods may be contrasted with all those currently available that employ “coherence theories” of knowledge. Under this designation are grouped positions that can seem very different (such as those of Poincaré, Duhem, Popper, Hempel, Quine, Kuhn, and Feyerabend) but are united by the idea that the most general statements of science are merely hypotheses. They may be conjectures, opinions, conventions, posits, paradigms, or even myths. The most we can claim to know from such generalities is that they are internally consistent and coherent with empirical data. Consistency is insufficient to establish the truth of a conceptual system because many different systems, perhaps an infinite number, can be logically consistent and cohere with recorded data. Such is the well-known problemof the empirical under-determination of theories. Francis Bacon’s Skeptical Recipes for New Knowledge suggests a new methodology that solves this fundamental problem of knowledge.
Francis Crick: Discoverer of the Genetic Code
by Matt RidleyFrancis Crick--the quiet genius who led a revolution in biology by discovering, quite literally, the secret of life--will be bracketed with Galileo, Darwin, and Einstein as one of the greatest scientists of all time. In his fascinating biography of the scientific pioneer who uncovered the genetic code--the digital cipher at the heart of heredity that distinguishes living from non-living things--acclaimed bestselling science writer Matt Ridley traces Crick's life from middle-class mediocrity in the English Midlands through a lackluster education and six years designing magnetic mines for the Royal Navy to his leap into biology at the age of thirty-one and its astonishing consequences. In the process, Ridley sheds a brilliant light on the man who forever changed our world and how we understand it.
Francis Galton: Pioneer of Heredity and Biometry
by Michael BulmerIf not for the work of his half cousin Francis Galton, Charles Darwin's evolutionary theory might have met a somewhat different fate. In particular, with no direct evidence of natural selection and no convincing theory of heredity to explain it, Darwin needed a mathematical explanation of variability and heredity. Galton's work in biometry—the application of statistical methods to the biological sciences—laid the foundations for precisely that. This book offers readers a compelling portrait of Galton as the "father of biometry," tracing the development of his ideas and his accomplishments, and placing them in their scientific context.Though Michael Bulmer introduces readers to the curious facts of Galton's life—as an explorer, as a polymath and member of the Victorian intellectual aristocracy, and as a proponent of eugenics—his chief concern is with Galton's pioneering studies of heredity, in the course of which he invented the statistical tools of regression and correlation. Bulmer describes Galton's early ambitions and experiments—his investigations of problems of evolutionary importance (such as the evolution of gregariousness and the function of sex), and his movement from the development of a physiological theory to a purely statistical theory of heredity, based on the properties of the normal distribution. This work, culminating in the law of ancestral heredity, also put Galton at the heart of the bitter conflict between the "ancestrians" and the "Mendelians" after the rediscovery of Mendelism in 1900. A graceful writer and an expert biometrician, Bulmer details the eventual triumph of biometrical methods in the history of quantitative genetics based on Mendelian principles, which underpins our understanding of evolution today.
Francis Of Assisi And His "canticle Of Brother Sun" Reassessed
by Brian MoloneyBringing the skills of a literary historian to the subject, Brian Moloney considers the genesis of Saint Francis of Assisi's Canticle of Brother Sun to show how it works as a carefully composed work of art. The study examines the saint's life and times, the structure of the poem, the features of its style, and the range of its possible meanings.
Francis Watkins and the Dollond Telescope Patent Controversy (Science, Technology and Culture, 1700-1945)
by Brian Gee edited by McConnellFrancis Watkins was an eminent figure in his field of mathematical and optical instrument making in mid-eighteenth century London. Working from original documents, Brian Gee has uncovered the life and times of an optical instrument maker, who - at first glance - was not among the most prominent in his field. In fact, because Francis Watkins came from a landed background, the diversification of his assets enabled him to weather particular business storms - discussed in this book - where colleagues without such an economic cushion, were pushed into bankruptcy or forced to emigrate. He played an important role in one of the most significant legal cases to touch this profession, namely the patenting of the achromatic lens in telescopes. The book explains Watkins's origins, and how and why he was drawn into partnership with the famous Dollond firm, who at that point were Huguenot incomers. The patent for the achromatic telescope has never been satisfactorily explained in the literature, and the author has gone back to the original legal documents, never before consulted. He teases out the problems, lays out the evidence, and comes to some interesting new conclusions, showing the Dollonds as hard-headed and ruthless businessmen, ultimately extremely successful. The latter part of the book accounts for the successors of Francis Watkins, and their decline after over a century of successful business in central London.
Franciscans and the Elixir of Life: Religion and Science in the Later Middle Ages (The Middle Ages Series)
by Zachary A. MatusOne of the major ambitions of medieval alchemists was to discover the elixir of life, a sovereign remedy capable not only of healing the body but of transforming it. Given the widespread belief that care for the body came at the cost of care for the soul, it might seem surprising that any Franciscan would pursue the elixir, but those who did were among its most outspoken and optimistic advocates. They believed they could distill a substance that would purify, transmute, and ennoble the human body as well as the soul. In an age when Christians across Europe were seeking material evidence for their faith and corporeal means of practicing their devotion, alchemy, and the elixir in particular, offered a way to bridge the terrestrial and the celestial.Framed as a history around science, Franciscans and the Elixir of Life focuses on alchemy as a material practice and investigates the Franciscan discourses and traditions that shaped the pursuit of the elixir, providing a rich examination of alchemy and religiosity. Zachary A. Matus makes new connections between alchemy, ritual life, apocalypticism, and the particular commitment of the Franciscan Order to the natural world, shedding new light on the question of why so many people claimed to have made, seen, or used alchemical compounds that could never have existed.