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Geothermie
by Ingrid Stober Kurt BucherNach einer Einführung in die Grundlagen der Geothermie werden die wichtigsten thermischen und hydraulischen Parameter in ihrer Bedeutung behandelt. Das nunmehr bereits in der 2., überarbeiteten und aktualisierten Auflage vorliegende Buch gibt einen Überblick über alle derzeit verfügbaren Nutzungssysteme der oberflächennahen und tiefen Geothermie und betrachtet diese bezüglich ihrer Effizienz und potentieller Umweltauswirkungen. Im Detail besprochen werden Planung, Bau und Betrieb von Erdwärmesonden, von hydrothermalen Anlagen und von EGS-Systemen. Spezielle Kapitel sind der Hydraulik, d.h. der Durchführung und Auswertung hydraulischer Tests, und der Hydrochemie, d.h. dem Themenbereich Lösung und Fällung, gewidmet. Mit diesem Buch wird erstmalig die Geothermie in ihrer vollen Breite abgedeckt.
Geotourism Potential of Georgia, the Caucasus: History, Culture, Geology, Geotourist Routes and Geoparks (Geoheritage, Geoparks and Geotourism)
by Irakli Gamkrelidze Avtandil Okrostsvaridze Kakhaber Koiava Ferando MaisadzeGeorgia’s territory represents a real “natural geological laboratory,” exposing magmatic, metamorphic and sedimentary rocks, ranging from the Neoproterozoic to the Quaternary. After a brief presentation of Georgia’s history and culture, the authors present the stratigraphy, rock types of individual tectonic zones of Georgia, their tectonic structure and paleotectonic reconstructions of the Caucasus.This book describes the three main geotourism routes of Georgia meticulously: 1. Tbilisi-Pasanauri-Kazbegi (along the Georgian Military Road), 2. Tbilisi-Zugdidi-Mestia-Ushguli and 3. Tbilisi-Khashuri-Vardzia, which cross different parts of Fold Systems of the Greater and Lesser Caucasus and Transcaucasian Intermountain area.The following potential geoparks are described in this book: 1. Sataplia dinosaur footprints together with Sataplia and Prometheus caves; 2. Tskaltubo resort-town and mineral water deposit; 3. Borjomi resort-town and mineral water deposit; 4. Kazbegi Quaternary volcanoes and Keli volcanic highland;5. Dariali Paleozoic granitoid massif; 6. Dmanisi hominids site and the Mashavera gorge basaltic flow; 7. Dashbashi canyon; 8.Uplistsikhe rock-cut town and Kvakhvreli cave complex; 9.Udabno - Upper Miocene marine and continental deposits and David Gareja monastery complex;10. Dedoplistskaro - Vashlovani protected areas and mud volcanoes.
Geriatric Imaging
by Ali Guermazi Giuseppe Guglielmi Wilfred C. PehIn the elderly, the coexistence of various diseases, the presence of involutional and degenerative changes, and the occurrence of both physical and cognitive problems represent "the norm." It is therefore important to know how to distinguish the healthy elderly from those in need of treatment as a sound basis for avoiding overdiagnosis and overtreatment. This aspect is a central theme in Geriatric Imaging, which covers a wide range of applications of different imaging techniques and clearly explains both the potential and the limitations of diagnostic imaging in geriatric patients. Individual sections are devoted to each major region or system of the body, and a concluding section focuses specifically on interventional procedures. The book, written by recognized experts in the field, is superbly illustrated and will be an ideal resource for geriatricians, radiologists, and trainees.
Geriatric Neuropsychology: Practice Essentials (Studies on Neuropsychology, Neurology and Cognition)
by Shane S. Bush Thomas A. MartinThe text provides a lifespan developmental approach to neuropsychology. It addresses the many issues in neuropsychological assessment that differ between younger and older adults. It describes the symptoms, neuropathology, diagnostic considerations, and treatment options of common neurological disorders associated with aging. It also addresses special considerations related to geriatric neuropsychology, such as ethical issues, family systems issues, decision-making capacity, cultural consideration, and medical/medication/substance use issues. Additionally, a list of resources for the elderly and their families is also provided.
Geriatric Rehabilitation: From Bedside to Curbside (Rehabilitation Science in Practice Series)
by K. Rao PoduriGeriatric Rehabilitation addresses the fact that this is an age in which individuals have increasing longevity, better health care, education and expectations of health care which present new, increasing and even radical challenges to health care providers. The care of our older patients in rehabilitation settings demands the broad understanding of the key differences in strategies to care for older adults. The combined skills embraced in rehabilitation and geriatrics are presenting unprecedented opportunities for both fields to make substantive and even ground-breaking improvements in the lives of millions of older adults who entrust their lives to us. Rarely in one’s medical career are such opportunities so evident and achievable. Geriatric Rehabilitation edited by Dr. K. Rao Poduri, MD. FAAPMR draws on a distinguished group of authors who are the front-line providers of care to the older adults. This book presents the full spectrum of the unique care needs of older patients who need the combined skills of physical medicine and geriatrics. It provides an easily accessible means of acquiring and improving these new skills for all those involved in geriatric care.
Germ Cell Development: Methods and Protocols (Methods in Molecular Biology #2770)
by Marco Barchi Massimo De FeliciThis detailed volume explores techniques for the isolation, purification, and establishment of in vitro germ cell (GS) systems at different stages of development in a variety of organisms, including chickens, mice, rats, and humans. The book additionally describes cutting-edge analytic and informatic tools to study germ cell development at the single cell level and meiotic recombination. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Germ Cell Development: Methods and Protocols provides new insight into the understanding of basic biological aspects of germ cell biology, as well as the opportunity for in vitro manipulation of germ cells for toxicology studies and for genetic intervention.
Germ Cell Development in C. elegans
by Tim SchedlGerm cells in sexually reproducing metazoa, through the germline lineage, are the route by which genetic material and cytoplasmic constituents are passed from one generation to the next in the continuum of life. Chapters in this book review germ cell development in the model organism Caenorhabditis elegans, discussing the biology, the genetics and the molecular mechanisms for various processes, as well as drawing comparisons with other organisms. Processes discussed include specification of germ cell fate, meiosis, gametogenesis, environmental/ physiological controls, epigenetics and translational control, fertilization and the oocyte-to-embryo transition. This book thus provides a comprehensive picture of the germline lineage and the continuum of life for the worm.
Germ Cell Protocols, Volume 1: Sperm and Oocyte Analysis
by Heide SchattenGerm cell research has produced enormous advances in recent years and more recently has entered into an explosive phase of new discoveries with the introduction of transgenic technologies and nuclear cloning. In Germ Cell Protocols, expert laboratory investigators describe in step-by-step detail a series of powerful techniques for the molecular and genetic analysis of germ cells in a variety of different reproductive systems. Chosen for their proven success in advancing our understanding of germ cells, these methods cover sperm and egg activation, motility, fertilization, nuclear development, nuclear cloning, the molecular characterization of specific events, and the imaging of cell structures. Volume 1: Sperm and Oocyte Analysis focuses on sperm cells, oocyte analysis, oocyte maturation, fertilization, and preparation techniques. Highlights include in vitro maturation and fertilization of human, porcine, and canine oocytes; the cryopreservation of sperm cells; establishment of an in vitro spermatogenesis system; visualization of sperm accessory structures; and motility assays of spermatozoa. Each readily reproducible protocol is described in step-by-step detail and contains an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. An accompanying second volume, Molecular Embryo Analysis, Live Imaging, Transgenesis, and Cloning, contains methods for molecular egg analysis, live egg imaging, nuclear cloning, oocyte preservation, and nuclear transfer. <P><P> Comprehensive and cutting-edge, Germ Cell Protocols offers both novice and established researchers a gold-standard collection of hard-to-find methods for high impact research, diverse procedures that are easy-to-follow, well-illustrated, and allow a cross-species transfer of knowledge from lower vertebrates to higher mammalian systems.
Germ Cell Protocols,Volume 2: Molecular Embryo Analysis, Live Imaging, Transgenesis, and Cloning
by Heide SchattenGerm cell research has produced enormous advances in recent years and more recently has entered into an explosive phase of new discoveries with the introduction of transgenic technologies and nuclear cloning. In Germ Cell Protocols, expert laboratory investigators describe in step-by-step detail a series of powerful techniques for the molecular and genetic analysis of germ cells in a variety of different reproductive systems. Chosen for their proven success in advancing our understanding of germ cells, these methods cover sperm and egg activation, motility, fertilization, nuclear development, nuclear cloning, the molecular characterization of specific events, the imaging of cell structures, and the cryopreservation of germ cells. Volume 2: Molecular Embryo Analysis, Live Imaging, Transgenesis, and Cloning focuses on molecular egg analysis, live egg imaging, nuclear cloning, oocyte cryopreservation, and nuclear transfer. Highlights include the identification and characterization of Oct-4, germline chromatin silencing by RNAi, cDNA subtraction and cloning in the field of trophoblast/placental development, and selective ablation. There are also methods for PCR-based cloning, differentiating embryonic stem cells into embryonic bodies, live imaging of mammalian embryos using multiphoton microscopy, and the cloning of pig, cattle, rabbit, and mouse oocytes. Each readily reproducible protocol is described in step-by-step detail and contains an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. An accompanying earlier volume, Sperm and Oocyte Analysis, focuses on sperm cells, oocyte analysis, oocyte maturation, fertilization, and preparation techniques.<P><P> Comprehensive and cutting-edge, Germ Cell Protocols offers both novice and established researchers a gold-standard collection of hard-to-find methods for high impact research, diverse procedures that are easy-to-follow, well-illustrated, and allow a cross-species transfer of knowledge from lower vertebrates to higher mammalian systems.
The Germ Code
by Jason TetroSince the dawn of the human race, germs have been making us sick. Whether the ailment is a cold, the flu, diabetes, obesity or certain cancers, the likely cause is germs. Our ancient enemies have four families - bacteria, viruses, fungi, and protozoa - and many names: Ebola, E. coli, salmonella, norovirus, gonorrhea. . . Human beings are engaged in a "war on germs," in which we develop ever-more sophisticated weapons and defensive strategies. But it is a war we can never win. Our best plan for staying as healthy is to choose our battles carefully, and try to co-exist with germs as best we can. The Germ Code is a wise, witty and wonderfully readable guide to our relationship with these infinitesimal but infinitely powerful creatures. Microbiologist Jason Tetro takes us outside the lab and shows the enormous influence of germs upon humanity's past, present and future. He unlocks the mysteries of "the germ code" to reveal how these organisms have exploited our every activity and colonized every corner of the earth. From his own research and personal experience, Tetro relates how the most recent flu pandemic happened, how others may have been averted and how more may come about if we aren't careful. He also explains that not every germ is our foe, and offers advice on harnessing the power of good germs to stay healthy and make our planet a better place. The Germ Code is a fascinating journey through an unseen world, an essential manual to living in harmony with germs and a life-enhancing (as well as life-saving!) good read.
The Germ Files
by Jason TetroDoes for microbiology what Dr. Joe Schwarcz's Brain Fuel did for chemistry: informs and entertains with accessible mini-essays.Jason Tetro, author of The Germ Code, is back with a very different book but the same message: microbes are amazing, they deserve our respect and we should learn to live with them in harmony. The way we feel, think, look and even interact with the world is affected by the germs in and around us. Despite their reputation for making us ill, germs also keep us alive and healthy. They even offer us relationship advice: the millions of bacteria shared in a first kiss send the brain strong messages about compatibility. In a series of brief, brilliant essays, arranged into themes such as health, child care, sex and the environment, Jason Tetro is here again to advise us and amaze us about germs. They enjoy breast milk, and help look after our babies in return for it; feed them artificial sweeteners, though, and they're capable of showing their displeasure by making us put on weight. If we upset their balance, they can make us depressed or encourage us to drink too much and eat junk food. One way of maintaining that balance is for us to take probiotics--but do they really stay in the body long enough to do any good? Yes--so long as you choose the type that bribes the immune system with a selection of rich chemicals. Some items are purely fun, some are there to boggle the mind, some might just save your life. All are designed to improve our relations with germs for the benefit of human health and happiness.From the Trade Paperback edition.
Germ Hunter: A Story about Louis Pasteur
by Elaine Marie AlphinGrowing up in the 1830s, Louis Pasteur saw the horrifying effects of diseases like rabies and tuberculosis. Filled with curiosity and imagination, Pasteur began a lifelong search for answers to his many questions about diseases. Although many scientists disagreed with his unusual ideas, his discoveries made him famous. Through his dedication and insight, Pasteur saved millions of lives and laid the groundwork for future medical advancements.
Germ Theory: Medical Pioneers in Infectious Diseases (ASM Books)
by Robert P. GaynesGerm Theory: Medical Pioneers in Infectious Diseases,SECOND EDITION From the ancient worlds of Hippocrates and Avicenna to the early 20th century hospitals of Paul Ehrlich and Lillian Wald to the modern-day laboratories of François Barré-Sinoussi and Barry Marshall, Germ Theory brings to life the inspiring stories of medical pioneers whose work helped change the very fabric of our understanding of how we think about and treat infectious diseases. In beautifully crafted narratives, author Robert Gaynes describes and presents compelling stories, including How Edward Jenner, the pioneer of vaccination, faced down scores of naysayers How a chance discovery led Louis Pasteur to the idea that the virulence of microbes can be altered How scientists in France, the Netherlands, and Denmark produced penicillin during World War 2 while keeping their efforts hidden from the Nazis The second edition features three new chapters based on interviews with Nobel Laureates François Barré-Sinoussi and Barry Marshall, and former NIAID Director and medical advisor to seven U.S. presidents Anthony Fauci, detailing fascinating accounts from their careers, including their groundbreaking work in the areas of HIV, peptic ulcers, and COVID-19, respectively. Winner of a CHOICE Outstanding Academic Title award for its first edition, Germ Theory is required reading for anyone training or working in the field of infectious diseases or with an interest in microbes, the history of medicine, or how new discoveries can bring about paradigmatic shifts in thinking.
Germ Wars: The Politics of Microbes and America's Landscape of Fear
by Melanie ArmstrongThe United States government has spent billions of dollars to prepare the nation for bioterrorism despite the extremely rare occurrence of biological attacks in modern American history. Germ Wars argues that bioterrorism has emerged as a prominent fear in the modern age, arising with the production of new forms of microbial nature and the changing practices of warfare. In the last century, revolutions in biological science have made visible a vast microscopic world, and in this same era we have watched the rise of a global war on terror. Germ Wars demonstrates that these movements did not occur separately but are instead deeply entwined—new scientific knowledge of microbes makes possible new mechanisms of war. Whether to eliminate disease or create weapons, the work to harness and control germs and the history of these endeavors provide an important opportunity for investigating how biological natures shape modern life. Germ Wars aims to convince students and scholars as well as policymakers and activists that the ways in which bioterrorism has been produced have consequences for how people live in this world of unspecifiable risks.
German Political Thought and the Discourse of Platonism: Finding the Way Out of the Cave
by Paul BishopTaking Plato’s allegory of the cave as its starting-point, this book demonstrates how later European thinkers can be read as a reaction and a response to key aspects of this allegory and its discourse of enchainment and liberation. Focusing on key thinkers in the tradition of European (and specifically German) political thought including Kant, Marx, Hegel, Nietzsche, Heidegger, and the Frankfurt School, it relates them back to such foundational figures as Rousseau, Aristotle, and in particular Plato. All these thinkers are considered in relation to key passages from their major works, accompanied by an explanatory commentary which seeks to follow a conceptual and imagistic thread through the labyrinth of these complex, yet fascinating, texts. This book will appeal in particular to scholars of political theory, philosophy, and German language and culture.
German Rocketeers in the Heart of Dixie
by Dr Monique LaneyThis thought-provoking study by historian Monique Laney focuses on the U. S. government-assisted integration of German rocket specialists and their families into a small southern community soon after World War II. In 1950, Wernher von Braun and his team of rocket experts relocated to Huntsville, Alabama, a town that would celebrate the team, despite their essential role in the recent Nazi war effort, for their contributions to the U. S. Army missile program and later to NASA's space program. Based on oral histories, provided by members of the African American and Jewish communities, and by the rocketeers' families, co-workers, friends, and neighbors, Laney's book demonstrates how the histories of German Nazism and Jim Crow in the American South intertwine in narratives about the past. This is a critical reassessment of a singular time that links the Cold War, the Space Race, and the Civil Rights era while addressing important issues of transnational science and technology, and asking Americans to consider their country's own history of racism when reflecting on the Nazi past.
Germany: Geographies of Complexity (World Regional Geography Book Series)
by Olaf Kühne Florian WeberThis book addresses the highly differentiated spatial, social, cultural and demographic structure(s) of Germany, with a particular focus on the reciprocal relations between different levels of spatial development. The historical development of Germany serves as a background in order to provide context for the development of spatially relevant ideas and ideals (whether in relation to politics, landscape, or culture). In this regard, questions of divergence and convergence become highly salient. The book makes the complexity of spatial and social developments in Germany comprehensible. The neopragmatic approach adopted here allows bringing together different theoretical strands while providing a basis for independent regional geographic research at the same time. Beginning with an overview of the physical structures of Germany which provides the material point of departure for the societal development of Germany, key aspects of the German history are discussed. Particular attention is paid to the reciprocal influence between material substrate and notions of landscape. Here, specific ‘German’ trajectories of aesthetic and normative conceptions of landscape become clear. A common theme throughout the book are questions of divergence and of efforts towards convergence, which become evident when considering past and present economic, political, and demographic developments. Efforts to tackle current challenges, such as adapting to climate change and mitigating it, or securing raw materials, also become apparent. The complexity of spatial processes in Germany is illustrated in case study regions dealing with the challenges of structural change in traditional industrial regions (such as the Ruhr area), or e.g. efforts of Berlin to position and find itself as the capital of a unified Germany. Overall, the book shows how theory-driven regional geographic research can make spatiotemporal complexities tangible and comprehensible.
Germany's Ancient Pasts: Archaeology and Historical Interpretation since 1700
by Brent ManerIn Germany, Nazi ideology casts a long shadow over the history of archaeological interpretation. Propaganda, school curricula, and academic publications under the regime drew spurious conclusions from archaeological evidence to glorify the Germanic past and proclaim chauvinistic notions of cultural and racial superiority. But was this powerful and violent version of the distant past a nationalist invention or a direct outcome of earlier archaeological practices? By exploring the myriad pathways along which people became familiar with archaeology and the ancient past—from exhibits at local and regional museums to the plotlines of popular historical novels—this broad cultural history shows that the use of archaeology for nationalistic pursuits was far from preordained. In Germany’s Ancient Pasts, Brent Maner offers a vivid portrait of the development of antiquarianism and archaeology, the interaction between regional and national history, and scholarly debates about the use of ancient objects to answer questions of race, ethnicity, and national belonging. While excavations in central Europe throughout the eighteenth and nineteenth centuries fed curiosity about the local landscape and inspired musings about the connection between contemporary Germans and their “ancestors,” antiquarians and archaeologists were quite cautious about using archaeological evidence to make ethnic claims. Even during the period of German unification, many archaeologists emphasized the local and regional character of their finds and treated prehistory as a general science of humankind. As Maner shows, these alternative perspectives endured alongside nationalist and racist abuses of prehistory, surviving to offer positive traditions for the field in the aftermath of World War II. A fascinating investigation of the quest to turn pre- and early history into history, Germany’s Ancient Pasts sheds new light on the joint sway of science and politics over archaeological interpretation.
Germfree and Gnotobiotic Animal Models: Background and Applications
by Bernard S. WostmannThe germfree animal is reared in the laboratory to be bacteria free; its counterpart, the gnotobiotic animal, is exposed to select microorganisms. The need for such an animal model for use in biomedical studies was first expressed by Pasteur in the late 1800s. Subsequent development of germfree and gnotobiotic animals led to an explosion of studies on the effects of microflora and its components on the physiology and metabolism of the host. Germfree and Gnotobiotic Animal Models brings together the most notable points of early and recent studies and gives reference to the most pertinent literature.
Germinal Centers
by Dinis Pedro CaladoThis volume provides key methods and protocols from laboratories engaged in germinal centers (GC) research with the expectation of stimulating further research, and to aid scientists in the study of GC biology and pathology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Germinal Centers: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Germline Development
by Wai-Yee Chan Le Ann BlombergThe germline is unique in mammals as it is the only cell lineage that undergoes mitosis, meiosis, and differentiation, making these cells amenable to in-depth genomic and mechanistic studies. In Germline Development: Methods and Protocols, expert researchers provide a wide-ranging collection of techniques that can be applied to the study of both the male and female germline. As the techniques used for isolating and studying male and female germ cells are slightly dissimilar, the different technologies are grouped under two sections in this volume, namely, male germline and female germline. This collection brings the field of germline developmental studies together such that readers can find, in a single volume, techniques that allow the isolation of gonads with germ cells at different stages of development, the study of the genomics and epigenomics of germ cells, and an examination of the role of single genes in the developmental potential and function of germ cells. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and the avoidance of known pitfalls. Comprehensive and cutting-edge, Germline Development: Methods and Protocols serves as a comprehensive text to individuals, particularly researchers in reproductive and developmental biology, who are interested in studying cells of the germ lineage.
Germline Development in the Zebrafish: Methods and Protocols (Methods in Molecular Biology #2218)
by Roland DoschThis volume details a wide range of methods, ranging from beginner through advanced, used to further study zebrafish and fish germline.. Chapter guide readers through cultivating and manipulating germ cells, imaging of germline processes and the molecular analysis of their, protein, and RNA. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Germline Development in the Zebrafish: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Germline Stem Cells: Methods and Protocols (Methods in Molecular Biology #2677)
by Michael BuszczakThis third edition volume expands on the previous editions with new discussion on the latest techniques and model systems used to study germline stem cells. The chapters in this book cover topics such as analysis of the C. elegans germline stem cell pool; live imaging of the Drosophila testis stem cell niche; standardization of single-cell RNA-sequencing analysis workflow to study Drosophila ovary; 3D analysis of the intact mouse ovary; and derivation and primordial germ cell induction of intermediate pluripotent stem cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and practical, Germline Stem Cells: Methods and Protocols, Third Edition is a valuable resource for all researchers in the germ stem cell community interested in learning more about this developing field.
Germline Stem Cells
by Shree Ram Singh Steven X. HouIn this comprehensive and cutting-edge book, leading experts explore the parameters that define germline stem cells and the mechanisms that regulate the cell behavior in order to better isolate, characterize and maintain them. The volume begins by providing protocols for germline stem cell identification and regulation in model organisms, and concludes with detailed chapters covering current techniques involving in vitro culture and the applications of the cells.
Germs: Fact and Fiction, Friends and Foes
by Lesa Cline-RansomeCome meet the good, the bad, and the ugly—yes, germs!There’s so much to discover about germs. Did you know that germs make your stomach growl as they break down your food? Or that they can travel the world on anything from fleas and ticks to trains and buses? Told from the perspective of Sam the Salmonella, this informative picture book introduces young readers to helpful and harmful germs, exploring their discovery; the breakout of historic diseases; the invention of pasteurization, vaccination, and penicillin; and other fascinating details about the world of microscopic organisms. A Christy Ottaviano Book