- Table View
- List View
Genes and DNA: A Beginner's Guide to Genetics and Its Applications
by Charlotte OmotoCovering newsworthy aspects of contemporary biology—gene therapy, the Human Genome Project, DNA testing, and genetic engineering—as well as fundamental concepts, this book, written specifically for nonbiologists, discusses classical and molecular genetics, quantitative and population genetics—including cloning and genetic diseases—and the many applications of genetics to the world around us, from genetically modified foods to genetic testing. With minimal technical terminology and jargon, Genes and DNA facilitates conceptual understanding. Eschewing the organization of traditional genetics texts, the authors have provided an organic progression of information: topics are introduced as needed, within a broader framework that makes them meaningful for nonbiologists. The book encourages the reader to think independently, always stressing scientific background and current facts.
Genes and DNA: A Beginner's Guide to Genetics and Its Applications
by Omoto Charlotte K. Paul F. LurquinCovering newsworthy aspects of contemporary biology-gene therapy, the Human Genome Project, DNA testing, and genetic engineering-as well as fundamental concepts, this book, written specifically for nonbiologists, discusses classical and molecular genetics, quantitative and population genetics-including cloning and genetic diseases-and the many applications of genetics to the world around us, from genetically modified foods to genetic testing. With minimal technical terminology and jargon, Genes and DNA facilitates conceptual understanding. Eschewing the organization of traditional genetics texts, the authors have provided an organic progression of information: topics are introduced as needed, within a broader framework that makes them meaningful for nonbiologists. The book encourages the reader to think independently, always stressing scientific background and current facts.
Genes And Future People
by Walter GlannonAdvances in genetic technology in general and medical genetics in particular will enable us to intervene in the process of human biological development which extends from zygotes and embryos to people. This will allow us to control to a great extent the identities and the length and quality of the lives of people who already exist, as well as those we bring into existence in the near and distant future. Genes and Future People explores two general philosophical questions, one metaphysical, the other moral: (1) How do genes, and different forms of genetic intervention (gene therapy, genetic enhancement, presymptomatic genetic testing of adults, genetic testing of preimplantation embryos), affect the identities of the people who already exist and those we bring into existence? and (2) How do these interventions benefit or harm the people we cause to exist in the near future and those who will exist in the distant future by satisfying or defeating their interest in having reasonably long and disease-free lives?Genes and Future People begins by explaining the connection between genes and disease, placing genetic within a framework of evolutionary biology. It then discusses such topics as how genes and genetic intervention influence personal identity, what genetic testing of individuals and the knowledge resulting from it entails about responsibility to others who may be at risk, as well as how gene therapy and genetic enhancement can affect the identities of people and benefit or harm them. Furthermore, it discusses various moral aspects of cloning human beings and body parts. Finally, it explores the metaphysical and moral implications of genetic manipulation of the mechanisms of aging to extend the human life span. The aim Genes and Future People is to move philosophers, bioethicists, and readers in general to reflect on the extent to which genes determine whether we are healthy or diseased, our identities as persons, the quality of our lives, and our moral obligations to future generations of people.
Genes and Signal Transduction in Multistage Carcinogenesis
by Nancy H. ColburnThis book describes the identification and characterization of genetic loci that determine susceptibility to liver, mammary, or skin carcinogenesis in rodents. It focuses on protein kinases and phospholipases, and stress-related signal transduction.
Genes and the Bioimaginary: Science, Spectacle, Culture
by Deborah Lynn SteinbergGenes and the Bioimaginary examines the dramatic rise and contemporary cultural apotheosis of 'the gene'. The book traces not only the genetification of modern life but is also a journey through the complex relationship between science and culture. At the heart of this book are three interlinked questions. The first concerns the paradigmatic transformations of the 'genetics revolution': how can we understand the impact of genes on social arenas as diverse as law and agriculture, politics and medicine, genealogy and jurisprudence? Second, how has the language of genes come to pervade public discourse - as much a trope of personal narrative as of the popular imaginary? And third, how can we gain critical purchase not only on the conditions and consequences of a particular science, but on its projective seductions, the terms of its persuasion, and the dilemmas and anxieties provoked in its wake? Through a series of illuminating case studies ranging from 'gay genes' to 'Jew genes', to genes for crime; from CSI to the Innocence Project, from genetics (post)racial imaginary to its phantasies of redemption, the book examines the emergence of the gene as a pre-eminent locus of both scientific and social explanation, and as a powerful object of spectacle, projective phantasy and attachment. Genes and the Bioimaginary makes a distinctive contribution to our understanding of how knowledge comes to be not only powerful, but plausible.
Genes and the Environment
by Roy H. BurdonGenes and the Environment is concerned with genes and how their structures and activities can be influenced by current relevant environmental adversitises. The book aims to provide a brief, integrated coverage at a biochemical and molecular biological level of the various effects that environmental factors can have on our genes, and those of other
Genes, Brains, and Human Potential: The Science and Ideology of Intelligence
by Ken RichardsonFor countless generations people have been told that their potential as humans is limited and fundamentally unequal. The social order, they have been assured, is arranged by powers beyond their control. More recently the appeal has been to biology, specifically the genes, brain sciences, the concept of intelligence, and powerful new technologies. Reinforced through the authority of science and a growing belief in bio-determinism, the ordering of the many for the benefit of a few has become more entrenched. Yet scientists are now waking up to the influence of ideology on research and its interpretation. In Genes, Brains, and Human Potential, Ken Richardson illustrates how the ideology of human intelligence has infiltrated genetics, brain sciences, and psychology, flourishing in the vagueness of basic concepts, a shallow nature-versus-nurture debate, and the overhyped claims of reductionists. He shows how ideology, more than pure science, has come to dominate our institutions, especially education, encouraging fatalism about the development of human intelligence among individuals and societies. Genes, Brains, and Human Potential goes much further: building on work being done in molecular biology, epigenetics, dynamical systems, evolution theory, and complexity theory, it maps a fresh understanding of intelligence and the development of human potential. Concluding with an upbeat message for human possibilities, this synthesis of diverse perspectives will engender new conversations among students, researchers, and other interested readers.
Genes, Cells and Brains
by Hilary Rose Steven RoseOur fates lie in our genes and not in the stars, said James Watson, co-discoverer of the structure of DNA. But Watson could not have predicted the scale of the industry now dedicated to this new frontier. Since the launch of the multibillion-dollar Human Genome Project, the biosciences have promised miracle cures and radical new ways of understanding who we are. But where is the new world we were promised?In Genes, Cells, and Brains, feminist sociologist Hilary Rose and neuroscientist Steven Rose take on the bioscience industry and its claims. Examining the rivalries between public and private sequencers,the establishment of biobanks, and the rise of stem cell research, they ask why the promised cornucopia of health benefits has failed to emerge. Has bioethics simply become an enterprise? As bodies become increasingly commodified, perhaps the failure to deliver on these promises lies in genomics itself.
Genes, Determinism and God
by Denis AlexanderOver the past centuries the pendulum has constantly swung between an emphasis on the role of either nature or nurture in shaping human destiny, a pendulum often energised by ideological considerations. In recent decades the flourishing of developmental biology, genomics, epigenetics and our increased understanding of neuronal plasticity have all helped to subvert such dichotomous notions. Nevertheless, the media still report the discovery of a gene 'for' this or that behaviour, and the field of behavioural genetics continues to extend its reach into the social sciences, reporting the heritability of such human traits as religiosity and political affiliation. There are many continuing challenges to notions of human freedom and moral responsibility, with consequent implications for social flourishing, the legal system and religious beliefs. In this book, Denis Alexander critically examines these challenges, concluding that genuine free will, often influenced by genetic variation, emerges from an integrated view of human personhood derived from contemporary biology.
Genes, Environments and Interactions: Evolutionary and Quantitative Genetics Brought Up-to-date
by José M Álvarez-CastroGenetic effects are the core concepts from which quantitative genetics and the evolutionary synthesis emerged. The groundbreaking theory of genetic effects was first proposed over a century ago. This book revises that theory, both conceptually and mathematically, and brings it up-to-date. The theory here compiled is supplemented with non-previously-published developments covering the broadest spectrum of simultaneously multiallelic and multilocus architectures with autosomal and sex-linked lociArbitrary interactions (dominance, gene-gene, gene-environment, gene-sex, and parent-of-origin interactions) are accounted forBoth effects of allele substitutions from the reference of individual genotypes and in the context of populations are worked outPopulations are considered regardless of any departures from equilibrium frequencies (including both departures from Hardy-Weinberg, departures from linkage equilibrium, and non-random associations between/among genes and environments)All developments are derived under the same mathematical framework, so that transformations of genetic effects between different contexts are easily allowed In brief, this book enables novel applications to current empirical paradigms (like gene-mapping and genomic prediction) while adhering to the classical conceptualization of genetic effects and variance decomposition that let quantitative genetics and the evolutionary synthesis flourish. All relevant concepts are carefully clarified and discussed from a historical perspective. The theoretical developments presented in the book are illustrated by built-in cases and applications with real data. Reassuringly, the adequacy of the theory here presented is corroborated based on the fundamentals of model development.
Genes, Genesis, and God: Values and Their Origins in Natural and Human History
by Holmes Rolston IIIHolmes Rolston challenges the sociobiological orthodoxy that would naturalize science, ethics, and religion. The book argues that genetic processes are not blind, selfish, and contingent, and that nature is therefore not value-free. The author examines the emergence of complex biodiversity through evolutionary history. Especially remarkable in this narrative is the genesis of human beings with their capacities for science, ethics, and religion. A major conceptual task of the book is to relate cultural genesis to natural genesis. There is also a general account of how values are created and transmitted in both natural and human cultural history. The book is written by one of the most well-respected figures in the philosophy of biology and religion.
Genes, Genomes and Society: From Farming to Gene Editing and Beyond
by Röbbe WünschiersWith CRISPR/Cas gene editing tools in hand, we are currently experiencing a new dimension in genetic engineering. But where should the journey lead? Should we treat diseases or better repair them genetically? Will the new genetic engineering, combined with modern reproductive biology, lead to designer babies? And: May we allow a liberalization of these techniques as citizen science? New methods can precisely alter the genetic material - and they leave no traces. This gene and genome surgery thrives on increasing knowledge about the mode of action of genes, those trait-giving regions in the genome. This knowledge is being applied in practice, particularly in the breeding of more resistant and higher-yielding crops. And what about us? The author shows that gene variants have long been associated not only with diseases, but also with nutritional preferences or intelligence. Therapeutic and optimization options are close at hand. What effect does the environment have on the expression of genetic material? Genes can be shaped during a person's lifetime by the environment, nutrition or experiences and thus passed on to their offspring in a modified form. So, does society have a new form of long-term responsibility for (epi)genetic integrity? In this vividly and comprehensibly written book, the author explains the state of genetic engineering without assuming too much prior knowledge and invites an open dialogue on this ambivalent topic. Get your own idea of the fascinating yet intimidating possibilities of genetic engineering. Where do you stand on the issue? With the help of this book, you have the chance to form a differentiated opinion. This book is a translation of the original German 1st edition Generation Gen-Schere by Röbbe Wünschiers, published by Springer Fachmedien Wiesbaden GmbH, part of Springer Nature in 2019. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). The text was subsequently revised by the author. Springer Nature works continuously to further the development of tools for the production of books and on the related technologies to support the authors.
Genes, Giants, Monsters, and Men
by Joseph P. FarrellConsider the possibility that the history of the human race is not as simple as what has been taught in classroom textbooks. Consider the possibility that the evolutionary scientific explanation for mankind has ignored critical facts that are buried deep within the fossils and mankind's DNA. Consider the possibility that the religious stories that have often been the core basis for mankind's understanding of where it belongs in the history of creation may actually reveal a planet occupied with tyrannical giants and an elite highly intelligent race bent on genetic mutation.As horrifying as such possibilities are, Genes, Giants, Monsters, and Men sets forth a plausible theory revealing a hidden history of mankind and a possible reason that it has remained veiled for hundreds of thousands of years. With his well-documented style and breathtaking conclusions, Dr. Joseph P. Farrell pulls back the veil and takes the reader on an odyssey behind the mysterious history and myths of the human race.Joseph P. Farrell is a recognized scholar whose credentials include a PhD in philosophy from the University of Oxford. His literary contribution is a veritable resumé unto itself covering such fields as Nazi Germany, sacred literature, physics, finances, the Giza pyramids, and music theory. A renowned researcher with an eye to assimilate a tremendous amount of background material, Farrell is able to condense the best scholastic research in publication and draw insightful new conclusions on complex and controversial subjects.
Genes, Girls, and Gamow
by James D. WatsonIn the years following his and Francis Crick's towering discovery of DNA, James Watson was obsessed with finding two things: RNA and a wife. Genes, Girls, and Gamow is the marvelous chronicle of those pursuits. Watson effortlessly glides between his heartbreaking and sometimes hilarious debacles in the field of love and his heady inquiries in the field of science. He also reflects with touching candor on some of science's other titans, from fellow Nobelists Linus Pauling and the incorrigible Richard Feynman to Russian physicist George Gamow, who loved whiskey, limericks, and card tricks as much as he did molecules and genes. What emerges is a refreshingly human portrait of a group of geniuses and a candid, often surprising account of how science is done.From the Trade Paperback edition.
Genes in Development: Re-reading the Molecular Paradigm
by Eva M. Neumann-Held Christoph Rehmann-SutterIn light of scientific advances such as genomics, predictive diagnostics, genetically engineered agriculture, nuclear transfer cloning, and the manipulation of stem cells, the idea that genes carry predetermined molecular programs or blueprints is pervasive. Yet new scientific discoveries--such as rna transcripts of single genes that can lead to the production of different compounds from the same pieces of dna--challenge the concept of the gene alone as the dominant factor in biological development. Increasingly aware of the tension between certain empirical results and interpretations of those results based on the orthodox view of genetic determinism, a growing number of scientists urge a rethinking of what a gene is and how it works. In this collection, a group of internationally renowned scientists present some prominent alternative approaches to understanding the role of dna in the construction and function of biological organisms. Contributors discuss alternatives to the programmatic view of dna, including the developmental systems approach, methodical culturalism, the molecular process concept of the gene, the hermeneutic theory of description, and process structuralist biology. None of the approaches cast doubt on the notion that dna is tremendously important to biological life on earth; rather, contributors examine different ideas of how dna should be represented, evaluated, and explained. Just as ideas about genetic codes have reached far beyond the realm of science, the reconceptualizations of genetic theory in this volume have broad implications for ethics, philosophy, and the social sciences. Contributors. Thomas Brglin, Brian C. Goodwin, James Griesemer, Paul Griffiths, Jesper Hoffmeyer, Evelyn Fox Keller, Gerd B. Mller, Eva M. Neumann-Held, Stuart A. Newman, Susan Oyama, Christoph Rehmann-Sutter, Sahotra Sarkar, Jackie Leach Scully, Gerry Webster, Ulrich Wolf
Genes, Polymorphisms, and the Making of Societies: A Genetic Perspective of the Divergence between East and West (Revised and Extended Edition)
by Hippokratis KiarisOur genes determine to a large extent who we are and why we are different from others. In this book, Hippokratis Kiaris explores how various genetic polymorphisms in different ethnic populations may affect the development of distinct cultures and eventual
Genes, Technology, and Apocalypse: An Epilogue for Humanity
by Yochai AtariaThis book offers a critique of a certain contemporary discourse in popular science that consists of (1) identifying the origins and therefore essential nature of Homo Sapiens; and (2) identifying the nature of technology. The author’s critique is that this double gesture generates a deterministic worldview – man is evil and technology has its own necessity – that operates to exonerate humanity from responsibility to the horrors of the 20th century, epitomized in Auschwitz and Hiroshima, for example. The author situates this operation within what he identifies as an “apocalyptical-eschatological state of mind”. Yochai Ataria explains that the dynamics of technology and the quest for the first human are the two central vectors shaping both scientific and popular discourse today, highlighting the importance of understanding the deep connection between the two.
Genesis: The Scientific Quest for Life's Origin
by Robert M. HazenLife on Earth arose nearly 4 billion years ago, bursting forth from air, water, and rock. Though the process obeyed all the rules of chemistry and physics, the details of that original event pose as deep a mystery as any facing science. How did non-living chemicals become alive? While the question is (deceivingly) simple, the answers are unquestionably complex. Science inevitably plays a key role in any discussion of life's origins, dealing less with the question of why life appeared on Earth than with where, when, and how it emerged on the blasted, barren face of our primitive planet. Astrobiologist Robert Hazen has spent many years dealing with the fundamental questions of life's genesis. As an active research scientist, he is down deep in all the messy details that science has to offer on the subject, tracing the inexorable sequence of events that led to the complicated interactions of carbonbased molecules. As he takes us through the astounding process of emergence, we are witness to the first tentative steps toward life--from the unfathomable abundance of carbon biomolecules synthesized in the black vacuum of space to the surface of the Earth to deep within our planet's restless crust. We are privy to the breathtaking drama that rapidly unfolds as life prevails. The theory of emergence is poised to answer a multitude of questions--even as it raises the possibility that natural processes exist beyond what we now know, perhaps beyond what we even comprehend. Genesis tells the tale of transforming scientific advances in our quest for life's origins. Written with grace, beauty, and authority, it goes directly to the heart of who we are and why we are here.
Genesis: Artificial Intelligence, Hope, and the Human Spirit
by Henry A. Kissinger Eric Schmidt Craig MundieIn his final book, the late Henry Kissinger joins forces with two leading technologists to mount &“a profound exploration&” (Walter Isaacson) of the epochal challenges and opportunities presented by the revolution in Artificial Intelligence: a breakthrough that dramatically empowers people in all walks of life while also raising urgent questions about the future of humanity. As it absorbs data, gains agency, and intermediates between humans and reality, AI (Artificial Intelligence) will help us to address enormous crises, from climate change to geopolitical conflicts to income inequality. It might well solve some of the greatest mysteries of our universe and elevate the human spirit to unimaginable heights. But it will also pose challenges on a scale and of an intensity that we have never seen—usurping our power of independent judgment and action, testing our relationship with the divine, and perhaps even spurring a new phase in human evolution. The last book of elder statesman Henry Kissinger, written with technologists Craig Mundie and Eric Schmidt, Genesis charts a course between blind faith and unjustified fear as it outlines an effective strategy for navigating the age of AI.
Genesis: The Story of How Everything Began
by Guido TonelliA breakout bestseller in Italy, now available for American readers for the first time, Genesis: The Story of How Everything Began is a short, humanistic tour of the origins of the universe, earth, and life—drawing on the latest discoveries in physics to explain the seven most significant moments in the creation of the cosmos.Curiosity and wonderment about the origins of the universe are at the heart of our experience of the world. From Hesiod’s Chaos, described in his poem about the origins of the Greek gods, Theogony, to today’s mind-bending theories of the multiverse, humans have been consumed by the relentless pursuit of an answer to one awe inspiring question: What exactly happened during those first moments?Guido Tonelli, the acclaimed, award-winning particle physicist and a central figure in the discovery of the Higgs boson (the “God particle”), reveals the extraordinary story of our genesis—from the origins of the universe, to the emergence of life on Earth, to the birth of human language with its power to describe the world. Evoking the seven days of biblical creation, Tonelli takes us on a brisk, lively tour through the evolution of our cosmos and considers the incredible challenges scientists face in exploring its mysteries. Genesis both explains the fundamental physics of our universe and marvels at the profound wonder of our existence.
Genesis: The Ultimate Origin Story
by Guido TonelliWhat if the ancient Greeks were right, and the universe really did spring into being out of chaos and the void? How could we know? And what must its first moments have been like?To answer these questions, scientists are delving into all the hidden crevices of creation. Armed with giant telescopes and powerful particle accelerators, they probe the subtle mechanisms by which our familiar world came to be, and try to foretell the manner in which it will end.The result of all this collective effort is a complex story, stranger at times than even our most ancient creation myths. But its building blocks give us the power to work marvels our predecessors could scarcely comprehend. In Genesis, the CERN physicist and bestselling author Guido Tonelli sets out to do justice to that great story.
Genesis: The Deep Origin Of Societies
by Edward O. WilsonForming a twenty-first-century statement on Darwinian evolution, one shorn of “religious and political dogma,” Edward O. Wilson offers a bold work of scientific thought and synthesis. Asserting that religious creeds and philosophical questions can be reduced to purely genetic and evolutionary components, and that the human body and mind have a physical base obedient to the laws of physics and chemistry, Genesis demonstrates that the only way for us to fully understand human behavior is to study the evolutionary histories of nonhuman species. Of these, Wilson demonstrates that at least seventeen—among them the African naked mole rat and the sponge- dwelling shrimp—have been found to have advanced societies based on altruism and cooperation. Whether writing about midges who “dance about like acrobats” or schools of anchovies who protectively huddle “to appear like a gigantic fish,” or proposing that human society owes a debt of gratitude to “postmenopausal grandmothers” and “childless homosexuals,” Genesis is a pithy yet path-breaking work of evolutionary theory, braiding twenty-first-century scientific theory with the lyrical biological and humanistic observations for which Wilson is known.
Genesis and Development of a Scientific Fact
by Ludwik Fleck; edited by Thaddeus J. Trenn and Robert K. Merton; translated by Fred Bradley and Thaddeus J. TrennOriginally published in German in 1935, this monograph anticipated solutions to problems of scientific progress, the truth of scientific fact and the role of error in science now associated with the work of Thomas Kuhn and others. Arguing that every scientific concept and theory—including his own—is culturally conditioned, Fleck was appreciably ahead of his time. And as Kuhn observes in his foreword, "Though much has occurred since its publication, it remains a brilliant and largely unexploited resource." "To many scientists just as to many historians and philosophers of science facts are things that simply are the case: they are discovered through properly passive observation of natural reality. To such views Fleck replies that facts are invented, not discovered. Moreover, the appearance of scientific facts as discovered things is itself a social construction, a made thing. A work of transparent brilliance, one of the most significant contributions toward a thoroughly sociological account of scientific knowledge."—Steven Shapin, Science
Genesis and Development of a Scientific Fact
by Thaddeus J. Trenn Robert K. Merton Fred BradleyOriginally published in German in 1935, this monograph anticipated solutions to problems of scientific progress, the truth of scientific fact and the role of error in science now associated with the work of Thomas Kuhn and others. Arguing that every scientific concept and theory--including his own--is culturally conditioned, Fleck was appreciably ahead of his time. And as Kuhn observes in his foreword, "Though much has occurred since its publication, it remains a brilliant and largely unexploited resource." "To many scientists just as to many historians and philosophers of science facts are things that simply are the case: they are discovered through properly passive observation of natural reality. To such views Fleck replies that facts are invented, not discovered. Moreover, the appearance of scientific facts as discovered things is itself a social construction, a made thing. A work of transparent brilliance, one of the most significant contributions toward a thoroughly sociological account of scientific knowledge."--Steven Shapin, Science.