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Heroes & Villains: Inside the minds of the greatest warriors in history
by Frank McLynnIn the history of warfare, an elite group of men have attained almost legendary status through their courage, ambition and unrivalled military genius. But many of these same men possessed deep personal character flaws. In Heroes & Villains, acclaimed historian Frank McLynn focuses on six of the most powerful and magnetic leaders of all time: Spartacus, Attila the Hun, Richard the Lionheart, Cortés, Tokugawa Ieyasu and Napoleon. How did these mortal men rise to positions of seemingly invincible power? What were the motives, the personal strengths and often weaknesses that drove them to achieve what no one else dared? In six powerful portraits, McLynn brilliantly evokes the critical moments when each of these warriors proved themselves in battle, changing their own lives, the destiny of their people and, in some cases, the history of the world. We discover what drove Spartacus to take on the might of Rome against seemingly impossible odds, and how the young Napoleon rose to power in dramatic fashion at the Siege of Toulon. Heroes & Villains is more than a collection of individual biographies. By examining the complex psychologies of these extraordinary men, McLynn builds up a convincing profile of the ultimate warrior. Accompanying a major BBC television series, this brilliant book takes us into the minds of the greatest warriors in history.
Heroes of Environmental Diplomacy: Profiles in Courage
by Felix DoddsToday more than ever, when the world is beset by environmental, social, healthcare and economic challenges, we need courage in our politics, both nationally and globally. This book tells the stories, some for the first time, of twelve individuals who made heroic contributions to protecting our planet through ground-breaking international treaties. Can individuals change the world? Today, when impersonal forces and new technologies seem to be directing our lives and even our entire planet in ways we cannot control, this question feels more relevant than ever before. This book argues that we can all make a difference. It tells inspiring stories of individuals who have had a global impact that is beyond dispute, as well as others who have brought about change that is understated or hard to measure, where the scale of the impact will only become clear in years to come. While some are scientists, others are politicians, diplomats, activists, and even businesspeople. However, they all share the qualities of perseverance, patience, a willingness to innovate or try new approaches, and the endurance to continue over years, even decades, to pursue their goal. Drawing on interviews and the inside stories of those involved, each chapter follows one or more of these heroic individuals, a list which includes Luc Hoffmann, Mostafa Tolba, Maria Luiza Ribeiro Viotti, Raul Oyuela Estrada, Barack Obama and Paula Caballero. Presenting an uplifting and gripping narrative, this book is an invaluable resource for students, scholars, activists and professionals who are seeking to understand how consensus is reached in these global meetings and how individuals can have a genuine impact on preserving our planet and reinforcing the positive message that global cooperation can actually work.
Heroes of the Space Age: Incredible Stories of the Famous and Forgotten Men and Women Who Took Humanity to the Stars
by Rod PyleA NASA insider tells the exciting story of the people, some well-known but many unrecognized, who were responsible for so many daring space missions.Award-winning science writer Rod Pyle profiles the remarkable pilots, scientists, and engineers whose work was instrumental in space missions to every corner of our solar system and beyond. Besides heralded names like Neil Armstrong, John Glenn, and Gene Kranz, the author highlights some of the "hidden figures" who played crucial roles in the success of NASA, Soviet, and international space exploration. For example, Valentina Tereshkova was the first woman to travel into space, aboard Soviet spacecraft Vostok 6. American Margaret Hamilton was an accomplished mathematician and one of the first female software engineers to design programs for spaceflight, software that proved critical to the success of the moon landing. And Pete Conrad, "salty sailor of the skies," flew twice in the Gemini programs, landed on the moon in Apollo 12, and was the commander of the first crew to visit America's new Skylab space station--its first ever--in 1973.Complemented by many rarely-seen photos and illustrations, these stories of the highly talented and dedicated people, many of whom worked tirelessly behind the scenes, will fascinate and inspire.
Heroic Animals: 100 Amazing Creatures Great and Small
by Clare BaldingBobbie the Wonder dog crossed more than 2,500 miles of plains, desert and mountains to find his way home - and became the inspiration for Lassie. Cher Ami the pigeon, despite being shot twice, delivered a message that saved the lives of 194 soldiers in 1918.Trakr the police dog spent two days exhaustively searching Ground Zero and found the last survivor of the 9/11 attacks.Ever since Alexander the Great named a city after the horse who saved his life in battle (and another after his dog), human history wouldn't be the same without the awe-inspiring tales of amazing animals.Now BAFTA-winning presenter, no. 1 bestselling author and all-round national treasure Clare Balding picks out the most heroic and heartwarming (and sometimes hilarious) animals from history and tells their stories. From Simon the sea cat to Greyfriars Bobby's 14-year vigil over his master's grave, to the elephant that saved a small girl and Paul the World-Cup-predicting octopus, Heroic Animals brings to life incredible feats and moving moments which highlight the timeless special bond between human and animal.
Heroic Animals: 100 Amazing Creatures Great and Small
by Clare BaldingBobbie the Wonder dog crossed more than 2,500 miles of plains, desert and mountains to find his way home - and became the inspiration for Lassie. Cher Amithe pigeon, despite being shot twice, delivered a message thatsaved the lives of 194 soldiers in 1918.Trakr the police dog spent two days exhaustively searching Ground Zero and found the last survivor of the 9/11 attacks.Ever since Alexander the Great named a city after the horse who saved his life in battle (and another after his dog), human history wouldn't be the same without the awe-inspiring tales of amazing animals.Now BAFTA-winning presenter, no. 1 bestselling author and all-round national treasure Clare Balding picks out the most heroic and heartwarming (and sometimes hilarious) animals from history and tells their stories. From Simon the sea cat to Greyfriars Bobby's 14-year vigil over his master's grave, to the elephant that saved a small girl and Paul the World-Cup-predicting octopus, Heroic Animals brings to life incredible feats and moving moments which highlight the timeless special bond between human and animal.
Heroic Animals: 100 Amazing Creatures Great and Small
by Clare Balding100 of the most heroic, inspirational (and sometimes hilarious) animals from history, brought to life by national treasure, Clare Balding.Bobbie the Wonder dog crossed more than 2,500 miles of plains, desert and mountains to find his way home - and became the inspiration for Lassie. Cher Ami the pigeon, despite being shot twice, delivered a message that saved the lives of 194 soldiers in 1918.Trakr the police dog spent two days exhaustively searching Ground Zero and found the last survivor of the 9/11 attacks.Ever since Alexander the Great named a city after the horse who saved his life in battle (and another after his dog), human history wouldn't be the same without the awe-inspiring tales of amazing animals.Now BAFTA-winning presenter, no. 1 bestselling author and all-round national treasure Clare Balding picks out the most heroic and heartwarming (and sometimes hilarious) animals from history and tells their stories. From Simon the sea cat to Greyfriars Bobby's 14-year vigil over his master's grave, to the elephant that saved a small girl and Paul the World-Cup-predicting octopus, Heroic Animals brings to life incredible feats and moving moments which highlight the timeless special bond between human and animal.(P)2020 Hodder & Stoughton Limited
Heroines of Horticulture: A Celebration of Women Who Shaped North America's Gardening Heritage
by Stefan WhiteA celebration and a salute to 100 brave, determined, creative women over the past few centuries who have shaped North America’s heritage and landscapes through their horticulture work and contributions. Through tales of invention, creativity, dogged research, innovation, perspiration, and inspiration spanning from the early 1700s to the mid-1980s, Heroines of Horticulture offers readers insight into 100 influential women who met and overcame obstacles to contribute a horticulture legacy that has helped shape the land that surrounds us today in North America. Many of the featured women are unknown or forgotten figures of horticulture history, making this book an overdue opportunity to acknowledge their work and celebrate their achievements that have left a lasting legacy. Profiles include the following: Martha Danielle Logan (1704–1779): An early American botanist who was instrumental in seed exchanges between Britain and the North American colonies. She wrote an influential gardening advice column and was a major collector of plants endemic to the Carolinas. Annie Linda Jack (1839–1912): The first Canadian professional female garden writer. Upon her marriage, she had stipulated for 1 acre of land to be devoted to any department of horticulture she chose, the profits to be her own pocket money. She wrote about her experiences in the Rural New Yorker, under the title "A Woman's Acre." The American horticulturalist Liberty Hyde Bailey referred to Annie Linda Jack's garden as "one of the most original gardens I know." Mary Gibson Henry (1884–1967): An American botanist and plant collector from Lower Merion Township, Pennsylvania, near Philadelphia, who also served as president of the American Horticultural Society. The daylily Hymenocallis henryae is named in her honor. Nelva Weber (1908–1990): An American landscape architect who wrote extensively about landscape design. She opened her practice in 1945 in New York City. Prior to that, she worked on the Palisades Parkway with C. C. Combs. She was also employed by the architecture firm Shaw Maess & Murphy and later as a designer on city parks for the New York City Parks Department. And many more Heroines of Horticulture is the perfect addition to the shelves and coffee tables of gardening enthusiasts and women’s history and feminist history readers and makes a great gift for anyone with a love of gardening or landscape design and history.
Herpes Simplex Virus Protocols
by Alasdair R. Maclean S. Moira BrownAn outstanding collection of state-of-the-art experimental methods for herpes virology. These procedures range from the more biological in vivo maneuvers to the purely molecular, and are described in detail by selected experts to ensure reproducibility. Most of the protocols rely on the herpes simplex virus as prototype, so that it then becomes relatively easy to extrapolate and make the necessary modifications required for application to other herpesviruses, especially members of the alpha group, such as PRV and EHV.
Herpetological Osteopathology
by Bruce M. Rothschild Hans-Peter Schultze Rodrigo PellegriniAs scientific analysis of testable hypotheses has replaced the speculative approach to study of bone disease in recent and fossil amphibians and reptiles, the field has advanced from simply reporting observations to analyzing their implications. This process is predicated upon a reproducible data base which explains/diagnoses the nature of bony alterations and a secure review of the literature. Thereby hangs the rub. The herpetological literature are difficult to access (let alone read) and are scattered through many prominent and eclectic journals and in the lay literature. While older diagnoses often have not stood the test of time, the clarity of report descriptions usually allows confident identification of the underlying pathology.
Herpetology: An Introductory Biology of Amphibians and Reptiles
by Laurie J. Vitt Janalee P. CaldwellThe fourth edition of the textbook Herpetology covers the basic biology of amphibians and reptiles, with updates in nearly every conceptual area. Not only does it serve as a solid foundation for modern herpetology courses, but it is also relevant to courses in ecology, behavior, evolution, systematics, and morphology. Examples taken from amphibians and reptiles throughout the world make this book a useful herpetology textbook in several countries. Naturalists, amateur herpetologists, herpetoculturists, zoo professionals, and many others will find this book readable and full of relevant natural history and distributional information. Amphibians and reptiles have assumed a central role in research because of the diversity of ecological, physiological, morphological, behavioral, and evolutionary patterns they exhibit. This fully revised edition brings the latest research to the reader, ranging over topics in evolution, reproduction, behavior and more, allowing students and professionals to keep current with a quickly moving field.
Herrera's 'Plasmogenia' and Other Collected Works
by Juli Peretó Henderson James Cleaves Antonio Lazcano Ismael Ledesma Mateos Alicia Negrón-Mendoza Ervin SilvaThis book collects three outstanding examples of the work of Mexican biologist Alfonso Luis Herrera (1868-1943), a pioneer in experimental origins of life research. Two of the collected works appear here in English for the first time. Herrera's works represent the attempt to deal experimentally with the issue of an autotrophic origin of life, a possibility that was widely accepted prior to Alexander I. Oparin's ideas regarding the possibility of organic synthesis and the origin of life in an early Earth environment. An active promoter of Darwinian ideas in Latin America, Herrera was also among the first 20th century researchers to attempt to "create life in a test tube. " This collection shows the remarkable prescience of researchers in Mexico with regards to laboratory approaches to the problem of the origin of life. It also includes a modern commentary by researchers actively engaged in research in prebiotic evolution and the origins of life, and deeply concerned with the historical development of ideas in these fields. The list includes H. James Cleaves, Antonio Lazcano, Alicia Negrón-González and Juli Peretó, who discuss in detail the relevance of Herrera's ideas to modern theory and their historical context. The book will expose modern readers and researchers to currents of thinking that have been lost, largely to time and language inaccessibility, of a seminal early theoretical biologist.
Herschel at the Cape: Diaries and Correspondence of Sir John Herschel, 1834-1838
by David S. Evans Terence J. Deeming Betty Hall Evans Stephen GoldfarbSir John Herschel, one of the founders of Southern Hemisphere astronomy, was a man of extraordinarily wide interests. He made contributions to botany, geology, and ornithology, as well as to astronomy, chemistry, and mathematics. Throughout his scientific career he kept a diary, recording his public and private life. The diaries from 1834 to 1838, years spent making astronomical observations at the Cape of Good Hope, are reproduced in this book and prove to be much more than an ordinary scientist''s logbook. They present personal and social history, literary commentaries, the results of close observations of nature and numerous scientific experiments, the excitement of travel, political intrigues, gossip, and philosophical reflections--all interpreted through an alert and versatile mind. In the present transcription, the material has been enriched with selected correspondence of Sir John and his wife Lady Herschel (neé Margaret Brodie Stewart). Sir John devoted his working time at the Cape primarily to a systematic observation of the southern sky, complementing his earlier "sweeping" of the northern sky at Slough, England. He later became one of the founders of photography, but at the Cape he used a simple optical device, the camera lucida, in the production of numerous landscape drawings. Many of these, along with reproductions of sketches contained in the diaries and botanical drawings made by Sir John and Lady Herschel, are used to illustrate this book. Sir John was also a leading spirit in the foundation of the educational system of the Cape and a supporter of exploratory expeditions into the interior. As the son of Sir William Herschel, in his day the most famous British astronomer and the discoverer of the planet Uranus, Sir John was already celebrated when he arrived from England. Every individual of note, resident at the Cape or visiting, went to see him. He was supported in his work by his wife, who ran an enormous establishment and bore a huge family, but who nevertheless found time to travel in the country round the western Cape with him and to assist in his observations. The diaries and letters are supplemented by especially valuable editorial notes that provide much needed and highly interesting information concerning persons and events mentioned and described by Sir John. All the original manuscript material used in this volume is held by the Harry Ransom Center at the University of Texas at Austin. Sir John''s camera lucida drawings are from the South African Public Library in Cape Town. Sir John Herschel, one of the founders of Southern Hemisphere astronomy, was a man of extraordinarily wide interests. He made contributions to botany, geology, and ornithology, as well as to astronomy, chemistry, and mathematics. Throughout his scientific career he kept a diary, recording his public and private life. The diaries from 1834 to 1838, years he spent making astronomical observations at the Cape of Good Hope, are reproduced in this book and prove to be much more than an ordinary scientist''s logbook. They present personal and social history, literary commentaries, the results of close observations of nature and numerous scientific experiments, the excitement of travel, political intrigues, gossip, and philosophical reflections - all interpreted through an alert and versatile mind. In the present transcription, the material has been enriched with selected correspondence of Sir John and his wife Lady Herschel (née Margaret Brodie Stewart). Sir John devoted his working time at the Cape primarily to a systematic observation of the southern sky, complementing his earlier "sweeping" of the northern sky at Slough, England. He later became one of the founders of photography, but at the Cape he used a simple optical device, the camera lucida, in the production of numerous landscape drawings. Many of these, along with reproductions of sketches contained in the diaries and botanical drawings made by Sir John and Lady Herschel, are used to illustrate this book. Sir John was also a leading figure i...
Hersenen Hacking Geheimen
by Stephen MilesGeheimen die de professionals gebruiken om hun hersens te optimaliseren! Hersenen Hacking Geheimen: leren versnellen en op hetzelfde moment IQ, productiviteit, geheugen en focus verhogen Geheimen die de professionals gebruiken om hun Hersenen te optimaliseren! Met tientallen jaren aan beproefde strategieën laat dit e-boek u de snelste en meest effectieve manier zien om uw geheugen te upgraden. U leert hoe U de cognitie kunt verbeteren en het IQ kunt stimuleren in slechts een paar uur. Niet alleen dat, maar u zult meer gefocust zijn, meer en meer energie bereiken dan ooit tevoren. Wilt u weten hoe de beste en slimste ter wereld op zulke hoge niveaus presteren? Zelfs als u slechts een gemiddelde intelligentie hebt, kunt u ook de geheimen om dit soort prestaties te bereiken leren. In deze gids leert u beproefde technieken om uw geheugen te verbeteren. Wat is inbegrepen: - Efficiënt en snel trainingsprogramma. Productiviteit verhogen - Vergroot het geheugen. - meer focus - Verhoog de algehele intelligentie. + Veel meer! Als je je hersenen op de best mogelijke manier wilt trainen, dan is dit boek iets voor u.
Herwig Schopper: Scientist and Diplomat in a Changing World (Springer Biographies)
by James Gillies Herwig SchopperThis open access book is both a memoir and a biography. Born in Czechoslovakia in 1924, Herwig Schopper is one of the few people able to bear witness to 100 years of European history. His career has taken him from research to management to diplomacy, with a major part devoted to, and inspired by, CERN. Herwig enjoyed a rich childhood, spending his summers at his grandparent’s hotel on the Adriatic coast. It is there that he developed an interest in physics though eavesdropping on holidaying professors from Budapest and Belgrade who conversed in German. His youthful idyll was shattered by the annexation of the Sudetenland, which lead to him serving in the Luftwaffe signals corps. Working as a translator for the British administration in Hamburg after the war, he also enrolled at the University and was soon granted leave to travel outside Germany for his research. So began a long string of professional relationships with leading scientists of the day: Lise Meitner, Otto Frisch, Bob Wilson, Chien Shiung Wu, Masatoshi Koshiba and Sam Ting to name but a few. Herwig came to consider them all as friends. Through his long career, Herwig has played a leading role in institutions from Erlangen to Karlsruhe, and from DESY, where he was director from 1973 to 1980, to CERN, where he served as Director-General from 1981 to 1988. Since its foundation CERN has had two major missions: to conduct first-class scientific research and to foster peaceful relations between nations. Following this example Herwig has played a key role in pioneering the deployment of science for peace, notably through the SESAME laboratory in the Middle East. This book gives a full account of Herwig’s rich and varied life and concludes with his reflections on the challenges that society faces today.
Hesitant Fuzzy Decision Making Methodologies and Applications
by Zeshui Xu Huchang LiaoThis book offers a comprehensive and systematic introduction to the latest research on hesitant fuzzy decision-making theory. It includes six parts: the hesitant fuzzy set and its extensions, novel hesitant fuzzy measures, hesitant fuzzy hybrid weighted aggregation operators, hesitant fuzzy multiple-criteria decision-making with incomplete weights, hesitant fuzzy multiple criteria decision-making with complete weights information, and the hesitant fuzzy preference relation based decision-making theory. These methodologies are implemented in various fields such as decision-making, medical diagnosis, cluster analysis, service quality management, e-learning management and environmental management. A valuable resource for engineers, technicians, and researchers in the fields of fuzzy mathematics, operations research, information science, management science and engineering, it can also be used as a textbook for postgraduate and senior undergraduate students.
Het Rojas Dossier
by Luc Wyn Pierre MonteagudoBoekbeschrijving Dit is het verhaal van een wonderkind genaamd Hector Rafael, dat op basis van zijn ijzeren wil om tegenslag te overwinnen, een vooraanstaande NASA-astrofysicus en belangrijke wetenschapper werd bij de komst van de mens op de maan. Tijdens de Koude Oorlog stelde astrofysicus Héctor R. Rojas aan het ministerie van Buitenlandse Zaken een wetenschappelijk samenwerkingsproject voor tussen Venezuela en de Verenigde Staten om kennis te democratiseren en de wetenschap te onderwijzen die destijds op de Latijns-Amerikaanse en Europese universiteiten bekend was. Wat gebeurde er daarna? De feiten zijn verborgen gebleven achter een mantel van mysterie en geheimhouding, tot vandaag. Wat was de beslissing van Het Agentschap? Wat deden de betrokken regeringen? Wat zegt de door Kissinger ondertekende memo? Dompel jezelf onder in dit fascinerende verhaal en ontdek de oplossing van het raadsel.
Heteroaromatic Lipoxin A4 Analogues
by Colm DuffyIn this thesis Colm Duffy reviews the chemistry and biology of stable lipoxin analogues. Colm has prepared for the first time ever a pyridine-containing LXA4 analogue in enantiomerically pure form. Biological evaluation determined that both epimers at the benzylic position suppress key cytokines known to be involved in inflammatory disease, with the (R)-epimer proving most efficacious. Moreover the author developed an excellent route to a related thiophene-containing analogue that also showed interesting biological activity. Both routes have inspired further work in the synthesis of further heteroaromatic analogues for biological evaluation.
Heterocycles as Chiral Auxiliaries in Asymmetric Synthesis (Topics in Heterocyclic Chemistry #55)
by Manfred BraunThe series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.
Heterocycles from Carbenes and Nitrenes: Methods, Reactions and Synthetic Applications (Topics in Heterocyclic Chemistry #59)
by Michael P. Doyle Xinfang XuThis book provides researchers in the fields of organic chemistry, organometallic chemistry and homogeneous catalysis with an overview of recent developments in the applications of reactions involving carbene and nitrene intermediates directed to the synthesis of heterocyclic compounds. Multiple pathways through which diverse heterocyclic compounds are accessed occur from a variety of carbene and nitrene precursors through C-H/X-H insertions, cycloadditions, ylide transformations, rearrangements, and cascade reactions. Catalytic processes that form metallo-carbenes and nitrenes offer unparalleled chemo-, regio-, and stereo-selectivities. Insights are provided into the scope of these methodologies and the inherent control of catalyst ligands on reaction selectivities.
Heterocycles in Life and Society
by Alan R. Katritzky Anatoly Soldatenkov Alexander F. PozharskiiHeterocycles in Life and Society is an introduction to the chemistry of heterocyclic compounds, focusing on their origin and occurrence in nature, biochemical significance and wide range of applications. Written in a readable and accessible style, the book takes a multidisciplinary approach to this extremely important area of organic chemistry.Topics covered include an introduction to the structure and properties of heterocycles; the key role of heterocycles in important life processes such as the transfer of hereditary information, how enzymes function, the storage and transport of bioenergy, and photosynthesis; applications of heterocycles in medicine, agriculture and industry; heterocycles in supramolecular chemistry; the origin of heterocycles on primordial Earth; and how heterocycles can help us solve 21st century challenges. For this second edition, Heterocycles in Life and Society has been completely revised and expanded, drawing on a decade of innovation in heterocyclic chemistry. The new edition includes discussions of the role of heterocycles in nanochemistry, green chemistry, combinatorial chemistry, molecular devices and sensors, and supramolecular chemistry. Impressive achievements include the creation of various molecular devices, the recording and storage of information, the preparation of new organic conductors, and new effective drugs and pesticides with heterocyclic structures. Much new light has been thrown on various life processes, while the chemistry of heterocycles has expanded to include new types of heterocyclic structures and reactions, and the use of heterocyclic molecules as ionic liquids and proton sponges.Heterocycles in Life and Society is an essential guide to this important field for students and researchers in chemistry, biochemistry, and drug discovery, and scientists at all levels wishing to expand their scientific horizon.
Heterocycles in Natural Product Synthesis
by Krishna C. Majumdar Shital K. ChattopadhyayFilling a gap on the market, this handbook and ready reference is unique in its discussion of the usefulness of various heterocyclic systems in the synthesis of natural products. Clearly structured for easy access to the information, each chapter is devoted to a certain class of heterocycle, providing a tabular presentation of the natural products to be covered containing the particular heterocyclic ring system along with their biological profile, occurrence and most important physical properties, backed by the appropriate references. In addition, the application of the heterocyclic system to the synthesis of natural products ic covered in detail. Of great interest to organic, natural products, medicinal and biochemists, as well as those working in the pharmaceutical and agrochemical industry.
Heterocycles via Cross Dehydrogenative Coupling: Synthesis and Functionalization
by Ananya Srivastava Chandan K. JanaThis book discusses the developments in the synthesis and functionalization of different heterocycles based on the formation of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds using cross-dehydrogenative coupling (CDC). Consisting of 13 chapters, the book systematically describes the advances in the synthesis and functionalization of nitrogen, oxygen, and sulfur-containing heterocycles. It also discusses the various mechanistic pathways to help readers gain an in-depth understanding of the CDC reactions of heterocycles. Lastly, in order to promote green chemistry, it addresses a range of metal-free CDC reactions of heterocycles – an area that has attracted significant attention in both academic and industrial research.
Heterocycles: Synthesis, Catalysis, Sustainability, and Characterization
by Teresa M.V.D. Pinho e Melo Marta PineiroA must-read handbook on heterocycle chemistry with a focus on sustainability Heterocycles feature prominently in our daily life—they are essential for pharmaceuticals, agrochemicals, and fine chemicals. More, numerous natural, bioactive products contain heterocyclic compounds. As a result, heterocyclic chemistry continues to be one of the most important areas of study in organic chemistry. Heterocycles provides an important reference on a wide range of topics relating to heterocyclic chemistry, with a heavy emphasis on sustainable methods and greener syntheses. The book describes state-of-the-art synthetic methods, such as photochemical reactions, dearomatization reactions, organocatalysis, transition metal catalysis, and biocatalysis. It also covers: Sustainable methods, like flow chemistry, mechanochemistry, and multicomponent synthesis Strategies for the synthesis of heterocyclic macrocycles and medium-sized rings Characterization of heterocyclic compounds Heterocycles is a useful reference for organic chemists, natural products chemists, catalytic chemists, and medicinal chemists in academia and industry.
Heterocyclic Chemistry (Fifth Edition)
by John A. Joule Keith MillsThis book has so closely matched the requirements of its readership over the years that it has become the first choice for chemists worldwide. Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, the vast majority of organic work done in the pharmaceutical and agrochemical industries is heterocyclic chemistry. The fifth edition of Heterocyclic Chemistry maintains the principal objective of earlier editions - to teach the fundamentals of heterocyclic reactivity and synthesis in a way that is understandable to second- and third-year undergraduate chemistry students. The inclusion of more advanced and current material also makes the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds in industry. Fully updated and expanded to reflect important 21st century advances, the fifth edition of this classic text includes the following innovations: Extensive use of colour to highlight changes in structure and bonding during reactions Entirely new chapters on organometallic heterocyclic chemistry, heterocyclic natural products, especially in biochemical processes, and heterocycles in medicine New sections focusing on heterocyclic fluorine compounds, isotopically labeled heterocycles, and solid-phase chemistry, microwave heating and flow reactors in the heterocyclic context Essential teaching material in the early chapters is followed by short chapters throughout the text which capture the essence of heterocyclic reactivity in concise resumés suitable as introductions or summaries, for example for examination preparation. Detailed, systematic discussions cover the reactivity and synthesis of all the important heterocyclic systems. Original references and references to reviews are given throughout the text, vital for postgraduate teaching and for research scientists. Problems, divided into straightforward revision exercises, and more challenging questions (with solutions available online), help the reader to understand and apply the principles of heterocyclic reactivity and synthesis.