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Human Nature and the Evolution of Society
by Stephen K. SandersonIf evolution has changed humans physically, has it also affected human behavior? Drawing on evolutionary psychology, sociobiology, and human behavioral ecology, Human Nature and the Evolution of Society explores the evolutionary dynamics underlying social life. In this introduction to human behavior and the organization of social life, Stephen K. Sanderson discusses traditional subjects like mating behavior, kinship, parenthood, status-seeking, and violence, as well as important topics seldom included in books of this type, especially gender, economies, politics, foodways, race and ethnicity, and the arts. Examples and research on a wide range of human societies, both industrial and nonindustrial, are integrated throughout. With chapter summaries of key points, thoughtful discussion questions, and important terms defined within the text, the result is a broad-ranging and comprehensive consideration of human society, thoroughly grounded in an evolutionary perspective.
Human Nature and the Evolution of Society
by Stephen K. SandersonIf evolution has changed humans physically, has it also affected human behavior? Drawing on evolutionary psychology, sociobiology, and human behavioral ecology, Human Nature and the Evolution of Society explores the evolutionary dynamics underlying social life. In this introduction to human behavior and the organization of social life, Stephen K. Sanderson discusses traditional subjects like mating behavior, kinship, parenthood, status-seeking, and violence, as well as important topics seldom included in books of this type, especially gender, economies, politics, foodways, race and ethnicity, and the arts. Examples and research on a wide range of human societies, both industrial and nonindustrial, are integrated throughout. With chapter summaries of key points, thoughtful discussion questions, and important terms defined within the text, the result is a broad-ranging and comprehensive consideration of human society, thoroughly grounded in an evolutionary perspective.
Human Nature As Capacity
by Nigel RapportWhat is it to be human? What are our specifically human attributes, our capacities and liabilities? Such questions gave birth to anthropology as an Enlightenment science. This book argues that it is again appropriate to bring "the human" to the fore, to reclaim the singularity of the word as central to the anthropological endeavor, not on the basis of the substance of a human nature - "To be human is to act like this and react like this, to feel this and want this" - but in terms of species-wide capacities: capabilities for action and imagination, liabilities for suffering and cruelty. The contributors approach "the human" with an awareness of these complexities and particularities, rendering this volume unique in its ability to build on anthropology's ethnographic expertise.
Human Nature in an Age of Biotechnology
by Tamar SharonNew biotechnologies have propelled the question of what it means to be human - or posthuman - to the forefront of societal and scientific consideration. This volume provides an accessible, critical overview of the main approaches in the debate on posthumanism, and argues that they do not adequately address the question of what it means to be human in an age of biotechnology. Not because they belong to rival political camps, but because they are grounded in a humanist ontology that presupposes a radical separation between human subjects and technological objects. The volume offers a comprehensive mapping of posthumanist discourse divided into four broad approaches--two humanist-based approaches: dystopic and liberal posthumanism, and two non-humanist approaches: radical and methodological posthumanism. The author compares and contrasts these models via an exploration of key issues, from human enhancement, to eugenics, to new configurations of biopower, questioning what role technology plays in defining the boundaries of the human, the subject and nature for each. Building on the contributions and limitations of radical and methodological posthumanism, the author develops a novel perspective, mediated posthumanism, that brings together insights in the philosophy of technology, the sociology of biomedicine, and Michel Foucault's work on ethical subject constitution. In this framework, technology is neither a neutral tool nor a force that alienates humanity from itself, but something that is always already part of the experience of being human, and subjectivity is viewed as an emergent property that is constantly being shaped and transformed by its engagements with biotechnologies. Mediated posthumanism becomes a tool for identifying novel ethical modes of human experience that are richer and more multifaceted than current posthumanist perspectives allow for. The book will be essential reading for students and scholars working on ethics and technology, philosophy of technology, poststructuralism, technology and the body, and medical ethics.
Human-Nature Interactions: Exploring Nature’s Values Across Landscapes
by Ieva Misiune Daniel Depellegrin Lukas Egarter ViglThis edited volume aims to widen the discussion about the diversity of human-nature relationships and valuation methods and to stimulate new perspective that are needed to build a more sustainable future, especially in face of ongoing socio-environmental changes. Conceptual and empirical approaches, including qualitative, quantitative, and mixed methodologies have been used to highlight the importance of an integrative understanding of socio-ecological systems, where healthy ecosystems underpin the quality of life and societal activities largely drive environmental changes. Readers will obtain a comprehensive overview of the many and diverse ways the relationships between people and nature can be characterized. This includes understanding how people assign values to nature, discuss how human-nature interactions are shaped and provide examples of how these values and interactions can be systematically assessed across different land systems in Europe and beyond. This open access book is produced by internationally recognized scientists in the field but written in an accessible format to be of interest to a large audience, including prospective students, lecturers, young professionals and scientists embarking to the interdisciplinary field of socio-ecological research and environmental valuation.
The Human Nature of Birds: A Scientific Discovery with Startling Implications
by Theodore X. BarberA provocative new study of birds, humans, and the deepest prejudices of Western science--developed from six years of independent research by a behavioral scientist. In the spirit of the New York Times bestseller The Hidden Life of Dogs. Color photos.
Human Natures: Genes, Cultures, and the Human Prospect
by Paul R. EhrlichThe Bell Curve, The Moral Animal, The Selfish Gene -- these and a host of other books and articles have made a seemingly overwhelming case that our genes determine our behavior. Now, in a new book that is sure to stir controversy, one of the world's leading evolutionary biologists shows why most of those claims of genetic destiny cannot be true, and explains how the arguments often stem from a fundamental misunderstanding of evolution itself."You can't change human nature," the saying goes. But you can, Stanford biologist Paul Ehrlich shows us in Human Natures, and in fact, evolution is the story of those changing natures. He makes a compelling case that "human nature" is not a single, unitary entity, but is as diverse as humanity itself, and that changes in culture and other environmental variations play as much of a role in human evolution as genetic changes. We simply don't have enough genes to specify behavior at the level that is often asserted.Never has knowledge of our evolutionary past been more important to our future. Developing intelligent strategies for antibiotic use, pest control, biodiversity protection -- and even for establishing more equitable social arrangements -- all depend on understanding evolution and how it works. Using personal anecdote, vivid example, and stimulating narrative, Ehrlich guides us through the thicket of controversies over what science can and cannot say about the influence of our evolutionary past on everything from race to religion, from sexual orientation to economic development.A major work of synthesis and scholarship, Human Natures gives us the fruit of a lifetime's thought and research on evolution and environment by a modern master of scientific understanding. Ehrlich's innovative vision lights the way to a fresh view of human nature and evolution, bringing insight and clarity to urgent questions of where we are as a species, and where we may be headed.
Human Neural Stem Cells: From Generation to Differentiation and Application (Results and Problems in Cell Differentiation #66)
by Leonora BuzanskaThis book summarizes early pioneering achievements in the field of human neural stem cell (hNSC) research and combines them with the latest advances in stem cell technology, including reprogramming and gene editing. The powerful potential of hNSC to generate and repair the developing and adult CNS has been confirmed by numerous experimental in vitro and in vivo studies. The book presents methods for hNSC derivation and discusses the mechanisms underlying NSC in vitro fate decisions and their in vivo therapeutic mode of action.The long-standing dogma that the human central nervous system (CNS) lacks the ability to regenerate was refuted at the end of the 20th century, when evidence of the presence of neurogenic zones in the adult human brain was found. These neurogenic zones are home to human neural stem cells (hNSCs), which are capable of self-renewing and differentiating into neurons, astrocytes and oligodendrocytes. NSCs isolated from human CNS have a number of clinical advantages, especially the innate potential to differentiate into functional neural cells. Nevertheless, their full clinical exploitation has been hindered by limited access to the tissue and low expansion potential. The search for an alternative to CNS sources of autologous, therapeutically competent hNSCs was the driving force for the many studies proving the in vitro plasticity of different somatic stem cells to generate NSCs and their functional progeny. Now the era of induced pluripotent stem cells has opened entirely new opportunities to achieve research and therapeutic goals with the aid of hNSCs.
Human Neuroanatomy
by James R. AugustineHuman Neuroanatomy: An Introduction, 2nd Edition is a comprehensive overview of the anatomy of the human brain and spinal cord. The book is written at a level to be of use as a text for advanced students and a foundational reference for researchers, clinicians in the field. Building on the foundations of first edition, this revision looks to increase user-friendliness and clinical applicability through improved figures and the addition of illustrative case studies. Written by James R. Augustine, with decades of experience teaching and researching in the field, Human Neuroanatomy, authoritatively covers this fundamental area of study within the neurosciences.
Human Ocular Microbiome: Bacteria, Fungi and Viruses in the Human Eye
by S. ShivajiThis book provides an integrated review of the human ocular microbiome. It documents the discovery of ocular surface microbes by the conventional cultivable method and next generation sequencing technologies in both healthy and diseased (keratitis, uveitis, endophthalmitis, blepharitis, conjunctivitis etc.) eyes. The book further discusses the confounding factors that influence the microbiome, mycobiome and virome. The chapters cover niche-specificity with reference to skin, eyelid- margin, hands etc. It highlights the concept of core genera, dysbiosis and discriminating genera and covers the functional relevance of the dysbiotic microbiome, mycobiome and virome with respect to ocular diseases. The book includes topics on the relevance of molecular mechanisms, including quorum-sensing and mucin metabolism to ocular disorders, such as dry eye; and, microbiome-based therapies for treating of ocular disorders like vernal keratoconjunctivitis. The book is essential for microbiologists studying the human eye, ophthalmologists treating eye infection and trauma. It also caters to students of medical microbiology and medicine.
The Human Odyssey: Navigating the Twelve Stages of Life
by Thomas Armstrong"This is truly a major contribution — brilliant, beguiling, and as broad in concept as it is deep." — Jean Houston, PhD, author of The Possible HumanThomas Armstrong, Ph.D., an award-winning educator and expert on human development, offers a cross-cultural view of life's entire journey, from before birth to death to the possibilities of an afterlife. Dr. Armstrong cites both clinical research and anecdotal evidence in a comprehensive view of the challenges and opportunities we face at every stage of our development. His accessible narrative incorporates elements of history, literature, psychology, spirituality, and science in a fascinating guide to understanding our past as well as our future."I loved the tone, the pacing, the sense of audience, and especially the richness of the associations . . . It's a book that one would like to keep around — a guidebook even." — John Kotre Ph.D., co-author of Seasons of Life: The Dramatic Journey from Birth to Death "The Human Odyssey is superb, magnificent, astonishing, unique, engrossing, eminently readable, informative, enjoyable, entertaining, profound. What else? I could go on. I hadn't expected anything like so remarkable a book." — Joseph Chilton Pearce, author of The Crack in the Cosmic Egg and Magical Child "I have read through The Human Odyssey. It is in many ways impressive. I also think that it has great commercial potential. Many people will find attractive your dual focus on the scientific and the soul/spiritual dimensions." — Howard Gardner, Ph.D., The John H. and Elizabeth A. Hobbs Professor in Cognition and Education at the Harvard Graduate School of Education, author of Frames of Mind "I extend my congratulations to you for this monumental undertaking and wish you the very best for your impressive efforts." — Marian Diamond, Ph.D. Professor, Department of Integrative Biology, University of California, Berkeley; co-author of Magic Trees of the Mind; pioneer researcher into the effect of the environment on brain development; dissected Einstein's brain "I very much enjoyed The Human Odyssey. Your breadth of sources is remarkable, and you have put them all together in a smooth and integrative way. I think it will be informative for people, and also inspiring for them to make their stages of life more meaningful. Overall, this is an impressive tour de force." — Arthur Hastings, Ph.D., Professor and Director, William James Center for Consciousness Studies, Institute of Transpersonal Psychology; Past President, Association of Transpersonal Psychology "Extraordinary. I hope that it is read by many people." — Laura Huxley, widow of Aldous Huxley, founder of Children: Our Ultimate Investment, and author of This Timeless Moment, and The Child of Your Dreams "A wonderful and encyclopedic summary of human development." — Allan B. Chinen, M.D., Clinical Professor of Psychiatry, University of California, San Francisco; author of Once Upon a Mid-Life: Classic Stories and Mythic Tales to Illuminate the Middle Years and In the Ever After: Fairy Tales and the Second Half of Life "Absolutely remarkable. The Human Odyssey is written with lively scholarship and contains great depth and breadth, a wide range of fascinating materials, and many useful resources. It's a kind of 'everything book.'" — George Leonard, "the granddaddy of the consciousness movement" (Newsweek) and author of The Transformation and The Ultimate Athlete"The Human Odyssey provides readers with a fresh approach to developmental psychology. Dr. Armstrong has included a spiritual dimension of human growth that is lacking from most accounts but which is essential for a complete understanding of the human condition. It is a splendid, brilliant work." — Stanley Krippner, Ph.D., former president of the Association for Humanistic Psychology, author of Personal Mythology: The Psychology of Your Evolving Self, and co-editor of The Psychological Impact of War Trauma on Civilians: An International Perspective "An integral approach to human development, from birth to death, that provides practical information for all who
Human Origins: What Bones and Genomes Tell Us About Ourselves
by Rob Desalle Ian TattersallEver since the recognition of the Neanderthals as an archaic form of human in the mid-nineteenth century, the fossilized bones of extinct humans have been used by paleoanthropologists to explore human origins. These bones tell the story of how the earliest humans first emerged in Africa some 6 to 7 million years ago. The bones also reveal that as humans became anatomically and behaviorally more modern, they swept out of Africa in waves into Asia, Europe, and finally into the New World. Even as paleoanthropologists continued to make important discoveries, experts in genetics were looking at the human species from a very different angle. In 1953 James Watson and Francis Crick first envisioned the double helix structure of DNA, the basic building block of all life. In the 1970s it was shown that humans share 98.7 percent of their genes with the great apes--that in fact genetically we are more closely related to chimpanzees than chimpanzees are to gorillas. And most recently the entire human genome has been mapped--we now know where each of the genes are located on the DNA strands that make up our chromosomes. In Human Origins: What Bones and Genomes Tell Us about Ourselves, two of the worlds foremost scientists, geneticist Rob DeSalle and paleoanthropologist Ian Tattersall, show how research into the human genome confirms what fossil bones have told us about human origins. This unprecedented integration of the fossil and genomic records provides the most complete understanding possible of humanity's place in nature, its emergence from the rest of the living world, and the evolutionary processes that have molded human populations to be what they are today.
Human Origins: 7 million years and counting (Instant Expert Ser.)
by New ScientistWhere did we come from? Where are we going?Homo sapiens is the most successful, the most widespread and the most influential species ever to walk the Earth. In the blink of an evolutionary eye we have spread around the globe, taken control of Earth's biological and mineral resources, transformed the environment, discovered the secrets of the universe and travelled into space.Yet just 7 million years ago, we were just another species of great ape making a quiet living in the forests of East Africa. We do not know exactly what this ancestor was like, but it was no more likely than a chimpanzee or gorilla to sail across the ocean, write a symphony, invent a steam engine or ponder the meaning of existence. How did we get from there to here?Human Origins recounts the most astonishing evolutionary tale ever told. Discover how our ancestors made the first tentative steps towards becoming human, how we lost our fur but gained language, fire and tools, how we strode out of Africa, invented farming and cities and ultimately created modern civilisation - perhaps the only one of its kind in the universe. Meet your long-lost ancestors, the other humans who once shared the planet with us, and learn where the story might end. ABOUT THE SERIESNew Scientist Instant Expert books are definitive and accessible entry points to the most important subjects in science; subjects that challenge, attract debate, invite controversy and engage the most enquiring minds. Designed for curious readers who want to know how things work and why, the Instant Expert series explores the topics that really matter and their impact on individuals, society, and the planet, translating the scientific complexities around us into language that's open to everyone, and putting new ideas and discoveries into perspective and context.
Human Origins: 7 million years and counting (New Scientist Instant Expert)
by New ScientistWhere did we come from? Where are we going?Homo sapiens is the most successful, the most widespread and the most influential species ever to walk the Earth. In the blink of an evolutionary eye we have spread around the globe, taken control of Earth's biological and mineral resources, transformed the environment, discovered the secrets of the universe and travelled into space.Yet just 7 million years ago, we were just another species of great ape making a quiet living in the forests of East Africa. We do not know exactly what this ancestor was like, but it was no more likely than a chimpanzee or gorilla to sail across the ocean, write a symphony, invent a steam engine or ponder the meaning of existence. How did we get from there to here?Human Origins recounts the most astonishing evolutionary tale ever told. Discover how our ancestors made the first tentative steps towards becoming human, how we lost our fur but gained language, fire and tools, how we strode out of Africa, invented farming and cities and ultimately created modern civilisation - perhaps the only one of its kind in the universe. Meet your long-lost ancestors, the other humans who once shared the planet with us, and learn where the story might end. ABOUT THE SERIESNew Scientist Instant Expert books are definitive and accessible entry points to the most important subjects in science; subjects that challenge, attract debate, invite controversy and engage the most enquiring minds. Designed for curious readers who want to know how things work and why, the Instant Expert series explores the topics that really matter and their impact on individuals, society, and the planet, translating the scientific complexities around us into language that's open to everyone, and putting new ideas and discoveries into perspective and context.
Human Origins: 7 million years and counting (New Scientist Instant Expert)
by New ScientistThe story of how our ancestors made the first tentative steps towards becoming human, how we lost our fur but gained language, fire and tools, and how we strode out of Africa, invented farming and cities and ultimately created modern civilisation.Where did we come from? Where are we going?Homo sapiens is the most successful, the most widespread and the most influential species ever to walk the Earth. In the blink of an evolutionary eye we have spread around the globe, taken control of Earth's biological and mineral resources, transformed the environment, discovered the secrets of the universe and travelled into space.Yet just 7 million years ago, we were just another species of great ape making a quiet living in the forests of East Africa. We do not know exactly what this ancestor was like, but it was no more likely than a chimpanzee or gorilla to sail across the ocean, write a symphony, invent a steam engine or ponder the meaning of existence. How did we get from there to here?Human Origins recounts the most astonishing evolutionary tale ever told. Discover how our ancestors made the first tentative steps towards becoming human, how we lost our fur but gained language, fire and tools, how we strode out of Africa, invented farming and cities and ultimately created modern civilisation - perhaps the only one of its kind in the universe. Meet your long-lost ancestors, the other humans who once shared the planet with us, and learn where the story might end. ABOUT THE SERIESNew Scientist Instant Expert books are definitive and accessible entry points to the most important subjects in science; subjects that challenge, attract debate, invite controversy and engage the most enquiring minds. Designed for curious readers who want to know how things work and why, the Instant Expert series explores the topics that really matter and their impact on individuals, society, and the planet, translating the scientific complexities around us into language that's open to everyone, and putting new ideas and discoveries into perspective and context.(P)2018 Hodder & Stoughton Limited
Human Origins: 7 million years and counting (Instant Expert)
by New ScientistWhere did we come from? Where are we going?Homo sapiens is the most successful, the most widespread and the most influential species ever to walk the Earth. In the blink of an evolutionary eye we have spread around the globe, taken control of Earth's biological and mineral resources, transformed the environment, discovered the secrets of the universe and travelled into space.Yet just 7 million years ago, we were just another species of great ape making a quiet living in the forests of East Africa. We do not know exactly what this ancestor was like, but it was no more likely than a chimpanzee or gorilla to sail across the ocean, write a symphony, invent a steam engine or ponder the meaning of existence. How did we get from there to here?The Story of Human Origins recounts the most astonishing evolutionary tale ever told.Discover how our ancestors made the first tentative steps towards becoming human, how we lost our fur but gained language, fire and tools, how we strode out of Africa, invented farming and cities and ultimately created modern civilization - perhaps the only one of its kind in the Universe. Meet your long-lost ancestors, the other humans who once shared the planet with us, and learn where the story might end.
Human Osteology
by Tim D. WhiteHuman Osteology, Second Edition is designed for students and professionals who wish to advance their osteological skills in terms of accurately identifying human skeletal remains, however isolated and fragmentary. These remains can then be used to deduce information about the original lives of the deceased individuals. This book is an essential text for courses on the human skeleton, as well as a basic reference and field manual for professional osteologists and anatomists, forensic scientists, paleontologists, and archaeologists. Human Osteology, Second Edition includes nearly a decade of advances in osteological research since the first edition. Each chapter has been strengthened and updated, including a new chapter on molecular osteology and four new case studies drawn from more recent research. This edition also includes a valuable guide to electronic resources in osteology.
Human Paleoneurology
by Emiliano BrunerThe book presents an integrative review of paleoneurology, the study of endocranial morphology in fossil species. The main focus is on showing how computed methods can be used to support advances in evolutionary neuroanatomy, paleoanthropology and archaeology and how they have contributed to creating a completely new perspective in cognitive neuroscience. Moreover, thanks to its multidisciplinary approach, the book addresses students and researchers approaching human paleoneurology from different angles and for different purposes, such as biologists, physicians, anthropologists, archaeologists and computer scientists. The individual chapters, written by international experts, represent authoritative reviews of the most important topics in the field. All the concepts are presented in an easy-to-understand style, making them accessible to university students, newcomers and also to anyone interested in understanding how methods like biomedical imaging, digital anatomy and computed and multivariate morphometrics can be used for analyzing ontogenetic and phylogenetic changes according to the principles of functional morphology, morphological integration and modularity.
Human Paleontology and Prehistory
by Assaf Marom Erella HoversThe aim of the book is to present original and though-provoking essays in human paleontology and prehistory, which are at the forefront of human evolutionary research, in honor of Professor Yoel Rak (a leading scholar in paleoanthropology). The volume presents a collection of original papers contributed by many of Yoel's friends and colleagues from all over the globe. Contributions from experts around the globe fall roughly into three broad categories: Reflections on some of the broad theoretical questions of evolution, and especially about human evolution; the early hominins, with special emphasis on Australopithecus afarensis and Paranthropus; and the Neanderthals, that contentious group of our closest extinct relatives. Within and across these categories, nearly every paper addresses combinations of methodological, analytical and theoretical questions that are pertinent to the whole human evolutionary time span. This book will appeal most to scholars and advanced students in paleoanthropology, human paleontology and prehistoric archaeology.
Human Papillomavirus (HPV)-Associated Oropharyngeal Cancer
by Daniel L. Miller M. Sharon StackHead and neck squamous cell carcinoma (HNSCC), the sixth most prevalent cancer worldwide, remains a very difficult disease to treat and cure despite intensive investigation into molecular etiologies and tumor progression pathways. Due to public health efforts encouraging smoking cessation, the overall incidence of HNSCC has decreased in recent years in many countries. In contrast, the incidence of oropharyngeal squamous cell carcinoma (OPSCC) has increased significantly, and this subtype of HNSCC is commonly associated with human papillomavirus (HPV) infection. Moreover, individuals with HPV-positive OPSCC are generally younger and are frequently non-smokers, suggesting that HPV-associated OPSCC represents a distinct biologic entity. This volume summarizes the spectrum of current HPV-associated OPSCC research from the fundamental basic science to translational surgery and treatment approaches. Chapters are contributed by authoritative leaders in the fields of research and clinical care. Initial chapters address epidemiology, behavioral correlates of HPV infection, and racial disparities in oropharyngeal cancer. This is followed by chapters detailing HPV virology with focus on viral transformation, viral replication, and host response to viral infection. The molecular biology of HPV-associated OPSCC is investigated in chapters detailing alterations in signaling networks and unique mutational profiles of human tumors. Clinical presentation, surgical perspectives, and treatment paradigms specific to HPV-associated OPSCC conclude the volume. This comprehensive volume provides an up-to-date overview of both scientific discovery and clinical management of this emerging public health problem.
Human Parasites: Diagnosis, Treatment, Prevention
by Heinz MehlhornThe new edition of this textbook provides an up-to-date overview of the most important parasites in humans and their potential vectors. Climate change and globalization steadily favor the opportunities for parasites to thrive. These challenges call for the latest information on pathogen transmission routes and timely preventive measures.For each parasite, this book offers a concise summary in eleven sections:1. Naming2. Geographic distribution and epidemiology3. Morphology, biology and life cycle4. Disease symptoms5. Diagnosis6. Infection pathways7. Prophylaxis8. Incubation period9. Prepatency10. Patency11. Therapeutic optionsNumerous tables, diagrams and over 200 colorful illustrations highlight the main aspects of parasitic infestations and present suitable control measures. Moreover, 60 questions help to test readers’ theoretical knowledge of the field. Readers can additionally download the free Springer Nature Flashcards App and benefit from the digital study questions.In short, this work is highly recommended for anyone looking to delve into the field of human parasitology. It is intended for students of biology and human medicine, medical doctors, pharmacists and laboratory staff alike. Furthermore, persons who plan to visit or live longer in endemic regions will find essential information on necessary preventive and control measurements.
The Human Past: World Prehistory and the Development of Human Societies
by Chris ScarreTextbook on humans, from 6 million years ago to early civilizations.
Human Pathobiochemistry: From Clinical Studies to Molecular Mechanisms
by Toshitaka Oohashi Hirokazu Tsukahara Francesco Ramirez Chad L. Barber Fumio OtsukaThis textbook uses a case-study approach to present the core principles of biochemistry and molecular biology in the context of human disease to students who will be involved in patient care. The 29 clinical cases have been carefully selected to cover key scientific concepts and some common, and other not so common, diseases. While the principal focus is on topics relating to metabolic disease, further subjects such as connective tissue disorders, neurological disorders, auto-inflammatory disorders, infective diseases, and cancer are also addressed. Each chapter provides a specific patient report that includes the natural history, pertinent clinical laboratory data, physical findings, subsequent diagnosis, and therapy. This is followed by a comprehensive discussion of the normal biochemical processes and reactions pertaining to the case, along with the pathophysiological mechanisms of the disease. Graphical diagrams are provided in each chapter for ease of comprehension.
Human Performance and Situation Awareness Measures
by Valerie GawronThis book was developed to help researchers and practitioners select measures to be used in the evaluation of human/machine systems. The book begins with an overview of the steps involved in developing a test to measure human performance. This is followed by a definition of human performance and a review of human performance measures. Another section defines situational awareness with reviews of situational awareness measures. For both the performance and situational awareness sections, each measure is described, along with its strengths and limitations, data requirements, threshold values, and sources of further information. To make this reference easier to use, extensive author and subject indices are provided. <P><P>Features <li>Provides a short engineering tutorial on experimental design <li>Offers readily accessible information on human performance and situational awareness (SA) measures <li>Presents general description of the measure <li>Covers data collection, reduction, and analysis requirements <li>Details the strengths and limitations or restrictions of each measure, including proprietary rights or restrictions
Human Performance Modification
by Board on Behavioral, Cognitive, and Sensory Sciences Division of Behavioral and Social Sciences and Education National Research Council Division on Engineering and Physical Sciences Committee on Assessing Foreign Technology Development in Human Performance ModificationThe development of technologies to modify natural human physical and cognitive performance is one of increasing interest and concern, especially among military services that may be called on to defeat foreign powers with enhanced warfighter capabilities. Human performance modification (HPM) is a general term that can encompass actions ranging from the use of "natural" materials, such as caffeine or khat as a stimulant, to the application of nanotechnology as a drug delivery mechanism or in an invasive brain implant. Although the literature on HPM typically addresses methods that enhance performance, another possible focus is methods that degrade performance or negatively affect a military force's ability to fight. Advances in medicine, biology, electronics, and computation have enabled an increasingly sophisticated ability to modify the human body, and such innovations will undoubtedly be adopted by military forces, with potential consequences for both sides of the battle lines. Although some innovations may be developed for purely military applications, they are increasingly unlikely to remain exclusively in that sphere because of the globalization and internationalization of the commercial research base. Based on its review of the literature, the presentations it received and on its own expertise, the Committee on Assessing Foreign Technology Development in Human Performance Modification chose to focus on three general areas of HPM: human cognitive modification as a computational problem, human performance modification as a biological problem, and human performance modification as a function of the brain-computer interface. Human Performance Modification: Review of Worldwide Research with a View to the Future summarizes these findings.