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Analysis of Enzyme Reaction Kinetics (Enzyme Reaction Engineering)
by F. Xavier MalcataComprehensively introduces readers to modelling of rate of enzymatic reactions, including effects of physicochemical parameters Analysis of Enzyme Reaction Kinetics is the second set in a unique eleven-volume collection on Enzyme Reactor Engineering. It describes rate expressions pertaining to enzymatic reactions, including modulation by physicochemical factors, as well as tools for prediction and control of how fast substrates are transformed to products. Volume 1 details rate expressions mathematically derived from mechanistic postulates, and is complemented by appropriate statistical approaches to fit them to experimental data. Volume 2 discusses the effects of physical and chemical parameters upon the rates of both enzyme-catalyzed and enzyme-deactivation reactions. Starting with basic concepts and historical perspectives, the first volume introduces readers to the mathematics of rate expressions. It then goes on to cover kinetic features and the many forms of Michaelis & Menten’s-type rate expressions (single and multiple enzymes, autocatalysis, single and multiple substrates, multiphasic systems, etc.), and concludes with the statistical analysis of rate expressions – including the assessment of data, fitting of models to data, and generation of data themselves. The second volume introduces readers to physicochemical modulation of reaction rate – starting with basic concepts, and looking specifically at temperature-, mechanical force-, pH- and compound-driven effects: both unimodal and bimodal deactivation are considered. Analysis of Enzyme Reaction Kinetics 2V Set is a comprehensive work for those studying or working with enzyme reactions, or practitioners involved in the control of reactors. SERIES INFORMATION Enzyme Reactor Engineering is organized into four major sets: Enzyme Reaction Kinetics and Reactor Performance; Analysis of Enzyme Reaction Kinetics; Analysis of Enzyme Reactor Performance; and Mathematics for Enzyme Reaction Kinetics and Reaction Performance.
Analysis of Epidemiologic Data Using R (Synthesis Lectures on Mathematics & Statistics)
by Robert HirschThis book addresses the description and analysis of occurrence data frequently encountered in epidemiological studies. With the occurrence of Covid-19, people have been exposed to the analysis and interpretation of epidemiological data. To be informed consumers of this information, people need to understand the nature and analysis of these data. Effort is made to emphasize concepts rather than mathematics. Subjects range from description of the frequencies of disease to the analysis of associations between the occurrence of disease and exposure. Those analyses begin with simple associations and work up to complex relationships that involve the control of extraneous characteristics. Analyses rely on the statistical software R, which is freeware in wide use by professional epidemiologists and other scientists.
Analysis of Excitation and Ionization of Atoms and Molecules by Electron Impact (Springer Series on Atomic, Optical, and Plasma Physics #60)
by Afzal Chaudhry Hans KleinpoppenThe content of this book describes in detail the results of the present measurements of the partial and total doubly differential cross sections for the multiple-ionization of rare gas atoms by electron impact. These measurements show, beside other trends, the role of Auger transitions in the production of multiply ionized atoms in the region where the incident electron energy is sufficient to produce inner shell ionization. Other processes like Coster-Kronig transitions and shake off also contribute towards increasing the charge of the ions. The incident electron having energy of 6 keV, for example, in a collision with xenon atom can remove up to nine electrons! (*) X-ray-ion coincidence spectroscopy of the electron xenon atom collisions is also described. The present measurements of doubly differential cross sections for the dissociative and non-dissociative ionization of hydrogen, sulfur dioxide and sulfur hexa fluoride molecular gases by electron impact are also described in the text of this book. The results of the measurements for sulfur dioxide molecule show how this major atmospheric pollutant can be removed from the atmosphere by electron impact dissociation of this molecule. The present results of the measurements for sulfur hexa fluoride give an insight into the dissociation properties of this molecular gas, which is being so widely used as a gaseous insulator in the electrical circuits. The book also describes the present measurements of the polarization parameters of the fluorescence radiation emitted by the electron-impact-excited atoms of sodium and potassium. In these investigations the target atoms are polarized, therefore, the measurements of the polarization parameters give information about the electron atom interaction in terms of the interference, direct and exchange interaction channels.
Analysis of Genetic Association Studies (Statistics for Biology and Health)
by Gang Zheng Xiaofeng Zhu Yaning Yang Robert C. ElstonAnalysis of Genetic Association Studies is both a graduate level textbook in statistical genetics and genetic epidemiology, and a reference book for the analysis of genetic association studies. Students, researchers, and professionals will find the topics introduced in Analysis of Genetic Association Studies particularly relevant. The book is applicable to the study of statistics, biostatistics, genetics and genetic epidemiology. In addition to providing derivations, the book uses real examples and simulations to illustrate step-by-step applications. Introductory chapters on probability and genetic epidemiology terminology provide the reader with necessary background knowledge. The organization of this work allows for both casual reference and close study.
Analysis of Growth Factor Signaling in Embryos (Methods in Signal Transduction Series)
by Malcolm Whitman Amy K. SaterDevelopmental biologists have been driven to investigate growth factor signaling in embryos in order to understand the regulatory mechanisms underlying a given developmental process. Thus, it is critical to explore the technical methods and experimental designs for growth factor signaling in embryos.Focusing on specific pathways or pathway comp
Analysis of Hydrogeochemical Vulnerability (Springer Hydrogeology)
by Robyn Hannigan Constantin MoraruThis monograph instructs the reader on how to analyze the hydrogeochemical vulnerability. It introduces notions of geochemical signals, points of migration of pollutants in the unsaturated zone, and new hydrogeochemical classifications. Three test sites in the USA, Germany, and Moldova are described as case studies accompanied by illustrative data. The authors presuppose for future readers only the background mathematics and elementary knowledge of hydrogeology. The presented methodology is both for local and regional assessments. It is simple, does not need implication of high qualification specialists and can be applied to test the groundwater quality. The book is useful for undergraduate, graduate, master, and PhD students as well as water quality specialists, ecologists and geology professionals.
Analysis of Kinetic Reaction Mechanisms
by Tamás Turányi Alison S. TomlinChemical processes in many fields of science and technology, including combustion, atmospheric chemistry, environmental modelling, process engineering, and systems biology, can be described by detailed reaction mechanisms consisting of numerous reaction steps. This book describes methods for the analysis of reaction mechanisms that are applicable in all these fields. Topics addressed include: how sensitivity and uncertainty analyses allow the calculation of the overall uncertainty of simulation results and the identification of the most important input parameters, the ways in which mechanisms can be reduced without losing important kinetic and dynamic detail, and the application of reduced models for more accurate engineering optimizations. This monograph is invaluable for researchers and engineers dealing with detailed reaction mechanisms, but is also useful for graduate students of related courses in chemistry, mechanical engineering, energy and environmental science and biology.
Analysis of Membrane Lipids (Springer Protocols Handbooks)
by Rajendra Prasad Ashutosh SinghThis book provides a timely overview of analytical tools and methodological approaches for studying membrane lipids. It outlines the ground-breaking advances that have been made over the last two decades in high-throughput lipidomics, and in studying lipid-protein interactions, signalling pathways and the regulation of lipid metabolism.This user-friendly laboratory handbook is an ideal companion for membrane biologists, researchers, students, and clinicians alike. It is also well suited for teaching biochemistry, microbiology and biotechnology courses, making it a must-have for everyone whose work involves lipid research.
Analysis of Multifactorial Diseases
by T. Bishop P. ShamAnalysis of Multifactorial Diseases examines the evidence of genetic factors that increase susceptibility to a range of complex diseases and describes the approaches taken to identify these genes. It reviews the successes and failures and examines whether there are any general conclusions to be drawn from this current range of approaches.
Analysis of Nanoplastics and Microplastics in Food (Food Analysis & Properties)
by Leo M. L. Nollet and Khwaja Salahuddin SiddiqiThe world’s ever increasing use of plastics has created large areas of floating plastic waste in the oceans—so-called plastic soup. This floating plastic debris is gradually fragmenting into smaller particles which eventually become microplastics, and even nanoplastics. Analysis of Nanoplastics and Microplastics in Food compiles data on nanoplastics and microplastics in food. To date, there is some data on this, particularly for the marine environment. Fish show high concentrations, but because microplastics are mostly present in the stomach and intestines, they are usually removed and consumers are not exposed. But in crustaceans and bivalve molluscs like oysters and mussels, the digestive tract is consumed, so there is some exposure. Microplastics have also been reported in honey, beer, and table salt. Key Features: Discusses sampling and analysis of nano- and microplastics Details the impacts of plastic residues in diverse compartments of the environment Includes a discussion of microplastics in freshwater Discusses interactions of microplastics and POPs This book brings to light the reality—and dangers—of microplastics in food. Pollutants like polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs) can accumulate in microplastics. Some studies suggest that, after consuming microplastics in food, these substances may transfer into tissues. So, it is important to estimate the average intake. Since engineered nanoparticles (from different types of nanomaterials) can enter human cells, this reality can pose consequences for human health. Also available in the Food Analysis and Properties Series: Mass Spectrometry Imaging in Food Analysis, edited by Leo M. L. Nollet (ISBN: 978-1-138-37069-2) Proteomics for Food Authentication, edited by Leo M. L. Nollet and Semih Ӧtleş (ISBN: 978-0-367-20505-8) Food Aroma Evolution: During Food Processing, Cooking, and Aging, edited by Matteo Bordiga and Leo M. L. Nollet (ISBN: 978-1-138-33824-1) For a complete list of books in this series, please visit our website at: www.crcpress.com/Food-Analysis--Properties/book-series/CRCFOODANPRO
Analysis of Neural Data (Springer Series in Statistics)
by Robert E. Kass Uri T. Eden Emery N. BrownContinual improvements in data collection and processing have had a huge impact on brain research, producing data sets that are often large and complicated. By emphasizing a few fundamental principles, and a handful of ubiquitous techniques, Analysis of Neural Data provides a unified treatment of analytical methods that have become essential for contemporary researchers. Throughout the book ideas are illustrated with more than 100 examples drawn from the literature, ranging from electrophysiology, to neuroimaging, to behavior. By demonstrating the commonality among various statistical approaches the authors provide the crucial tools for gaining knowledge from diverse types of data. Aimed at experimentalists with only high-school level mathematics, as well as computationally-oriented neuroscientists who have limited familiarity with statistics, Analysis of Neural Data serves as both a self-contained introduction and a reference work.
Analysis of Neurogenic Disordered Discourse Production: From Theory to Practice
by Anthony Pak KongAnalysis of Neurogenic Disordered Discourse Production provides a comprehensive review and discussion of aphasia and its related disorders, their corresponding clinical discourse symptoms that speech-language pathologists and related healthcare professionals should address, and the different methods of discourse elicitation that are research- and clinically-oriented. Contemporary issues related to disordered/clinical discourse production are covered, and discussions of various treatment options in relation to discourse symptoms are included. Finally, the manifestation of discourse symptoms as a function of speakers’ bilingual/multilingual status and specific considerations related to clinical assessment and intervention are explored. Readers who want to learn the background and techniques of discourse analysis, refresh their knowledge of discourse production, update their knowledge of assessment and treatment of discourse production, and learn about contemporary issues of discourse annotation and analysis using existing computer software will find this book a valuable tool. With its comprehensive coverage, it offers a thorough understanding of the nature, assessment, and remediation of discourse deficits in aphasia and related disorders. Readers will also benefit from examples throughout the book that connect theory to real-life contexts of discourse production.
Analysis of Neurogenic Disordered Discourse Production: Theories, Assessment and Treatment
by Anthony Pak-Hin KongAnalysis of discourse production among speakers with acquired communication disorders is an important and necessary clinical procedure. This book provides a comprehensive review and discussion of aphasia and its related disorders, their corresponding clinical discourse symptoms that speech-and-language pathologists should address, and the different methods of discourse elicitation that are clinically and research oriented. This edition has been thoroughly updated throughout to include the latest research, including advances in word retrieval and discourse production, cognitive and multicultural aspects of disordered discourse production, application of technology to understand and evaluate spoken discourse, and evidence-based intervention of discourse impairments. Contemporary issues related to disordered/clinical discourse elicitation are added. Recent advancement in discourse analysis is covered and discussions of various treatment options of discourse symptoms are provided. Finally, the manifestation of discourse symptoms as a function of speakers’ multilingual/multi-cultural status and specific considerations related to clinical assessment and remediation are explored. As the only introductory text to include comprehensive coverage of basic knowledge of neurogenic disordered discourse, it is a must-read for students, clinicians, and researchers in various fields. Readers will also benefit from plenty of examples that provide a connection between the theoretical contents presented in the text and application to real-life contexts of discourse production.
Analysis of Oceanic Waters and Sediments
by Thomas Roy CromptonThe presence of concentrations of organic substances and cations in seawater is a matter of increasing concern to the water industry, environmentalists and the general public alike. It poses a threat of possible health hazards for humans, fish and crustacea. Until fairly recently, the analysis of seawater was limited to a number of major constituen
Analysis of Pesticides in Food and Environmental Samples, Second Edition
by Jose L. TadeoThis book provides a critical overview of analytical methods used for the determination of pesticide residues and other contaminants in food and environmental samples by modern instrumental analysis. It contains up-to-date material including recent trends in sample preparation, general methods used for pesticide analysis and quality assurance aspects, and chromatographic and immunoassay methods. The rest of the book describes particular analytical methods used for the determination of pesticides in food and soil, water and air. In addition, the levels of these chemicals found in food, their regulatory aspects and the monitoring of pesticides in the environment are described.
Analysis of Pesticides in Water: Volume I: Significance, Principles, Techniques, and Chemistry of Pesticides
by Alfred S.Y. ChauThis book, collected by Mr. Chau and Dr. Afghan, is devoted to the broad and important topic of pesticides. It examines important facets such as the significance of the problem, the chemistry of pesticides, and principles and techniques. It will provide excellent reference material for producers, users and testing agencies.
Analysis of Pesticides in Water: Volume II: Chlorine-and Phosphorus- Containing Pesticides
by Alfred S.Y. ChauThis book, collected by Mr. Chau and Dr. Afghan, is devoted to the broad and important topic of pesticides. It examines important facets such as the significance of the problem, the chemistry of pesticides, and principles and techniques. It will provide excellent reference material for producers, users and testing agencies.
Analysis of Piezoelectric Semiconductor Structures
by Jiashi YangThis book presents the mechanics of piezoelectric semiconductor structures where the main electromechanical coupling of interest is the interaction between mechanical fields and semiconduction. This volume stands as the first full book treatment of this multi-physical subject from the mechanics angle. The analysis of piezoelectric semiconductor structures and devices is an emerging and rapidly growing interdisciplinary area involving materials, electronics, and solid mechanics. It has direct applications in the new area of piezotronics and piezo-phototronics. The book is theoretical, beginning with a phenomenological framework and progressing to include solutions to problems fundamental to the theory and application. Dr. Yang illustrates how in piezoelectric semiconductors, mechanical fields interact with semiconduction through the piezoelectrically produced electric fields by mechanical loads. This provides the foundation of piezotronic and piezo-phototronic devices in which semiconduction is induced, affected, manipulated, or controlled by mechanical fields. Also discussing composite structures of piezoelectric dielectrics and nonpiezoelectric semiconductors as well as thermal effects, the book is an ideal basic reference on the topic for researchers.
Analysis of Post-Translational Modifications and Proteolysis in Neuroscience (Neuromethods #114)
by Jennifer Elizabeth Grant Hong LiThis volume highlights proteomics studiesof quantitative PTM changes in both peripheral and central nervous systemproteomes utilizing the most recent advances in mass spectrometry. Chaptersinclude practical information pertaining to the fundamentals of samplepreparation, liquid chromatography, and tandem mass spectrometry instrumentalanalysis and will elucidate best practices in the interpretation of data usingmodern bioinformatics approaches. Written for the popular Neuromethods series,chapters include the kind of detail and key implementation advice that ensuressuccessful results in the laboratory. Authoritativeand practical, Analysis of Post-Translational Modifications andProteolysis in Neuroscience aims to ensure successful resultsin the further study of this vital field.
Analysis of Protein Post-Translational Modifications by Mass Spectrometry
by Richard D. Unwin John R. GriffithsCovers all major modifications, including phosphorylation, glycosylation, acetylation, ubiquitination, sulfonation and and glycation Discussion of the chemistry behind each modification, along with key methods and references Contributions from some of the leading researchers in the field A valuable reference source for all laboratories undertaking proteomics, mass spectrometry and post-translational modification research
Analysis of Quantised Vortex Tangle (Springer Theses)
by Alexander John TaylorIn this thesis, the author develops numerical techniques for tracking and characterising the convoluted nodal lines in three-dimensional space, analysing their geometry on the small scale, as well as their global fractality and topological complexity---including knotting---on the large scale. The work is highly visual, and illustrated with many beautiful diagrams revealing this unanticipated aspect of the physics of waves. Linear superpositions of waves create interference patterns, which means in some places they strengthen one another, while in others they completely cancel each other out. This latter phenomenon occurs on 'vortex lines' in three dimensions. In general wave superpositions modelling e. g. chaotic cavity modes, these vortex lines form dense tangles that have never been visualised on the large scale before, and cannot be analysed mathematically by any known techniques.
Analysis of Samples of Clinical and Alimentary Interest with Paper-based Devices (Springer Theses)
by Emilia Witkowska NeryThis book presents two main sets of paper-basedanalytical systems. The first set is a platform for the analysis of glucose,cholesterol and uric acid in biological samples, and the second set is a cutting-edgeelectronic tongue system for the analysis of beverages (mineral water, beer,wine). This thesis also provides an extensive review of 33 methods ofenzyme immobilization on paper which have been evaluated to enhance the storagestability of the proposed system for biomarker detection. From a practical perspective, this thesis coversa diverse set of topics related to paper-based sensing, including colorimetricand electrochemical detection methods, different sets of architecture(spot-tests, lateral and tangential flow assays), methods of fabrication (waxprinting, cutting, impregnation with polymers), measurements instationary and flow conditions as well computer modeling of proposed systemsand sophisticated data analysis using chemometric techniques. This book isuseful for PhD students working in this or a related field who require detailedinformation about methodology and background to this research.
The Analysis of Starlight: Two Centuries of Astronomical Spectroscopy
by John B. HearnshawFirst published in 1987, this is the story of the analysis of starlight by astronomical spectroscopy. Beginning with Joseph Fraunhofer's discovery of spectral lines in the early nineteenth century, this new edition continues the story through to the year 2000. In addition to the key discoveries, it presents the cultural and social history of stellar astrophysics by introducing the leading astronomers and their struggles, triumphs and disagreements. Basic concepts in spectroscopy and spectral analysis are included, so both observational and theoretical aspects are described, in a non-mathematical framework. This new edition covers the final decades of the twentieth century, with its major advances in stellar astrophysics: the discovery of extrasolar planets, new classes of stars and the observation of the ultraviolet spectra of stars from satellites. The in-depth coverage makes it essential reading for graduate students working in stellar spectroscopy, professional and amateur astronomers, and historians of science.
Analysis of Survival Data with Dependent Censoring: Copula-Based Approaches (SpringerBriefs in Statistics)
by Takeshi Emura Yi-Hau ChenThis book introduces readers to copula-based statistical methods for analyzing survival data involving dependent censoring. Primarily focusing on likelihood-based methods performed under copula models, it is the first book solely devoted to the problem of dependent censoring. <P><P> The book demonstrates the advantages of the copula-based methods in the context of medical research, especially with regard to cancer patients’ survival data. Needless to say, the statistical methods presented here can also be applied to many other branches of science, especially in reliability, where survival analysis plays an important role. <P> The book can be used as a textbook for graduate coursework or a short course aimed at (bio-) statisticians. To deepen readers’ understanding of copula-based approaches, the book provides an accessible introduction to basic survival analysis and explains the mathematical foundations of copula-based survival models.
Analysis of the Electric Dipole Moment in the R-parity Violating Supersymmetric Standard Model (Springer Theses)
by Nodoka YamanakaIn this thesis the author discusses the phenomenology of supersymmetric models by means of experimental data set analysis of the electric dipole moment. There is an evaluation of the elementary processes contributing to the electric dipole moments within R-parity-violating supersymmetry, which call for higher-order perturbative computations. A new method based on linear programming is developed and for the first time the non-trivial parameter space of R-parity violation respecting the constraints from existing experimental data of the electric dipole moment is revealed. As well, the impressive efficiency of the new method in scanning the parameter space of the R-parity-violating sector is effectively demonstrated. This new method makes it possible to extract from the experimental data a more reliable constraint on the R-parity violation.