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Human Ring Chromosomes: A Practical Guide for Clinicians and Families
by Peining Li Thomas LiehrThis book presents chromosome-wise clinical cases following an evidence-based protocol, in addition to providing the scientific background on the mechanisms of human ring chromosome (RC) formation. Presence of RCs in a genome can lead to several rare genetic diseases. This book, edited by the leading experts Prof. Peining Li and Prof. Thomas Liehr, is the first comprehensive book on this topic.Over the past 60 years, banding cytogenetics, fluorescence in situ hybridization, chromosome microarray analysis, and whole genome sequencing have been used to diagnose cases with a RC. Ring syndrome of sever growth retardation and variable intellectual disability has been considered a common clinical feature for all RCs. Clinical heterogeneity of chromosome-specific deletion and duplication syndromes, gene-related organ and tissue defects, cancer predisposition to different types of tumors, and reproduction failure has been reported in the literature. However, the cases of RCs reportedin the literature account for less than 1% of its real occurrence. Current diagnostic practice lacks laboratory standards for analyzing cellular behavior and genomic imbalances of RCs to evaluate its compound effects on patients. The under-representation of clinical cases and the lack of comprehensive diagnostic analysis make challenging to establish accurate clinico-cytogenomic correlations. Given recent advances in genomic technology and organized efforts from peer experts, standardized cytogenomic diagnosis and evidence-based clinical management could be envisioned for all patients with RCs.Furthermore, supernumerary small ring chromosomes and the patient’s perspective are addressed—the latter by including family stories of RC-carrier relatives. Acquired RCs in various cancers are also discussed, as well as the potential role of RCs in research applications like iPSC cellular modeling and genomic editing.This book is a valuable reference for clinical geneticists, personnel in cytogenetics and molecular genetics laboratories, genetic counselors, and researchers in related fields.
Human Risk Assessment: The Role Of Animal Selection And Extrapolation
by M. V. Roloff; A. G. E. Wilson; W. E. Ribelin; W. P. Ridley; F. A. RueckerThis book explores the factors which are critical in the selection of an appropriate animal species for toxicology studies and the subsequent extrapolation of the data to humans. It provides some future directions for risk assessment activities at the Environmental Protection Agency.
Human-Robot Interaction: Evaluation Methods and Their Standardization (Springer Series on Bio- and Neurosystems #12)
by Céline Jost Brigitte Le Pévédic Tony Belpaeme Cindy Bethel Dimitrios Chrysostomou Nigel Crook Marine Grandgeorge Nicole MirnigThis book offers the first comprehensive yet critical overview of methods used to evaluate interaction between humans and social robots. It reviews commonly used evaluation methods, and shows that they are not always suitable for this purpose. Using representative case studies, the book identifies good and bad practices for evaluating human-robot interactions and proposes new standardized processes as well as recommendations, carefully developed on the basis of intensive discussions between specialists in various HRI-related disciplines, e.g. psychology, ethology, ergonomics, sociology, ethnography, robotics, and computer science. The book is the result of a close, long-standing collaboration between the editors and the invited contributors, including, but not limited to, their inspiring discussions at the workshop on Evaluation Methods Standardization for Human-Robot Interaction (EMSHRI), which have been organized yearly since 2015. By highlighting and weighing good and bad practices in evaluation design for HRI, the book will stimulate the scientific community to search for better solutions, take advantages of interdisciplinary collaborations, and encourage the development of new standards to accommodate the growing presence of robots in the day-to-day and social lives of human beings.
Human-Robot Interactions in Future Military Operations (Human Factors in Defence)
by Florian JentschSoldier-robot teams will be an important component of future battle spaces, creating a complex but potentially more survivable and effective combat force. The complexity of the battlefield of the future presents its own problems. The variety of robotic systems and the almost infinite number of possible military missions create a dilemma for researchers who wish to predict human-robot interactions (HRI) performance in future environments. Human-Robot Interactions in Future Military Operations provides an opportunity for scientists investigating military issues related to HRI to present their results cohesively within a single volume. The issues range from operators interacting with small ground robots and aerial vehicles to supervising large, near-autonomous vehicles capable of intelligent battlefield behaviors. The ability of the human to 'team' with intelligent unmanned systems in such environments is the focus of the volume. As such, chapters are written by recognized leaders within their disciplines and they discuss their research in the context of a broad-based approach. Therefore the book allows researchers from differing disciplines to be brought up to date on both theoretical and methodological issues surrounding human-robot interaction in military environments. The overall objective of this volume is to illuminate the challenges and potential solutions for military HRI through discussion of the many approaches that have been utilized in order to converge on a better understanding of this relatively complex concept. It should be noted that many of these issues will generalize to civilian applications as robotic technology matures. An important outcome is the focus on developing general human-robot teaming principles and guidelines to help both the human factors design and training community develop a better understanding of this nascent but revolutionary technology. Much of the research within the book is based on the Human Research and Engineering Directorate (HRED), U.S. Army Research Laboratory (ARL) 5-year Army Technology Objective (ATO) research program. The program addressed HRI and teaming for both aerial and ground robotic assets in conjunction with the U.S. Army Tank and Automotive Research and Development Center (TARDEC) and the Aviation and Missile Development Center (AMRDEC) The purpose of the program was to understand HRI issues in order to develop and evaluate technologies to improve HRI battlefield performance for Future Combat Systems (FCS). The work within this volume goes beyond the research results to encapsulate the ATO's findings and discuss them in a broader context in order to understand both their military and civilian implications. For this reason, scientists conducting related research have contributed additional chapters to widen the scope of the original research boundaries.
The Human Scaffold: How Not to Design Your Way Out of a Climate Crisis (Great Transformations #2)
by Josh BersonHumanity has precipitated a planetary crisis of resource consumption—a crisis of stuff. So ingrained is our stuff-centric view that we can barely imagine a way out beyond substituting a new portmanteau of material things for the one we have today.In The Human Scaffold, anthropologist Josh Berson offers a new theory of adaptation to environmental change. Drawing on niche construction, evolutionary game theory, and the enactive view of cognition, Berson considers cases in the archaeology of adaptation in which technology in the conventional sense was virtually absent. Far from representing anomalies, these cases exemplify an enduring feature of human behavior that has implications for our own fate.The time has come to ask what the environmental crisis demands of us not as consumers but as biological beings. The Human Scaffold offers a starting point.
Human Scent Evidence (Forensic Science Techniques Ser.)
by Paola A. Prada Allison M. Curran Kenneth G. FurtonDuring the last decade, scientific studies have supported using human scent as a biometric tool and indicator of the presence or absence of an individual at a crime scene. This book focuses on some of these recent advances in the use of human scent as forensic evidence. It examines theories of human odor production, the legal significance of results, and canine scent work from multiple search categories as described in the Scientific Working Group on Dog and Orthogonal detector Guidelines (SWGDOG). It also explores current trends in scent collection techniques, including devices, materials, and storage protocols.
Human Settlements: Urbanization, Smart Sector Development, and Future Outlook (Advances in 21st Century Human Settlements)
by Giuseppe T. CirellaThe answers to the questions of why and how people live where they live as well as how they maintain and integrate with one another are fundamental human settlement issues rooted in history and culture. Human settlements are historically linked to resource availability, fortification, and the mythos of civilizations. Cities play a central role in redefining the interface between human beings and nature. They have revolutionized the human experience by taming natural surroundings and building environments that are human-centric—often narrowing human life outside the experience of wilderness or the untamed. This book is divided into three parts, it examines urban development trends, explores perspectives in energy efficiency and agriculture security, and considers policy development and future scenarios in human-nature relations. It is a compendium of multidisciplinary work that challenges the directions of modernity and offers reference to alternatives. Authors come from a diverse background and international context to address common overarching theories facing current geography-specific problems. An interconnected overtone of the book attempts to link accelerated urbanization and settlement location to how societies are maintained and integrated. Human settlements are shaped by human ecology and the relationship between humans and their interaction with their environment. Two sectors central to human survival are specifically explored: energy and agriculture. Cutting-edge, smart development looks at the latest findings that reflect the on-going debate facing these sectors. A human settlement metric is envisioned in terms of the past, present, and future. This book is a unique attempt to combine a rethinking about human settlements for scientists, policy-makers, public officials, and people committed to improving urban life, society-wide. Possible agents to resolving human settlement problems include international cooperation and various mechanisms that interlace the international community. Methodological and applied aspects of sustainable management focus on topics such as adaptive knowledge sharing, renewable energy, climate change, agricultural planning, and policy development. An emphasis on scientific and technological advancement, from a bottom-up mapping of society, elucidates a better understanding of the role of knowledgeable societies in which need is considered alongside how such need can be sustained—advancing towards a more promising future.
Human Sexuality
by Roger R. HockHelp each student develop a sexual philosophy based on choice, awareness, and responsibility Human Sexuality presents a relatable overview of the discipline that inspires students to think critically about the sexual world and their place in it. By taking an interpersonal approach and encouraging each student to develop a personal sexual philosophy, author Roger Hock helps students connect the material covered to their real-life decisions and behaviors, boosting engagement with the course. Sensitivity to diverse groups – not only in terms of race and ethnicity, but also in terms of sexual orientation, age, sexual knowledge, and sexual experience – allows all students to feel as comfortable and open about sexual topics as possible. The Fourth Edition includes updated data as well as coverage of contemporary issues that dominate today's headlines to ensure currency and relevancy.
Human Sexuality: Making Informed Decisions
by David Knox Mark A Whatley Caroline SchachtProvides an understanding of the human reproductive system, the various factors that influence the sexual decisions that every individual make and guides us to making the right sexual decision putting into consideration all the outcomes/consequences of every option. The book lets us know we have a deliberate choice to make in a relationship, a healthy choice for both the body and mind.
Human Sexuality Today (6th Edition)
by Bruce M. KingThe sixth edition of Human Sexuality Today provides students with the information they need to make responsible decisions and helps them feel comfortable about themselves while learning about their sexuality.
The Human Side of Cancer: Living with Hope, Coping with Uncertainty
by Sheldon Lewis Jimmie C. HollandFor more than twenty years, Dr. Holland has pioneered the study of psychological problems of cancer patients and their families -- whom she calls "the real experts." In The Human Side of Cancer, she shares what she has learned from all of them about facing this life-threatening illness and what truly helps along the cancer journey. This book is the next best thing to sitting in Dr. Holland's office and talking with her about the uncertainty and anxiety elicited by this disease. And it is a book that inspires hope -- through stories of the simple courage of ordinary people confronting cancer.
Human Space Exploration (World Book's Solar System and Space Exploration Library)
by Karen Ingebretsen"Introduction to space exploration, providing to primary and intermediate grade students information on astronauts, space shuttles, and space stations. Includes fun facts, glossary, resource list and index."--Provided by publisher.
Human Spatial Navigation
by Arne D. Ekstrom Hugo J. Spiers Véronique D. Bohbot R. Shayna RosenbaumThe first book to comprehensively explore the cognitive foundations of human spatial navigationHumans possess a range of navigation and orientation abilities, from the ordinary to the extraordinary. All of us must move from one location to the next, following habitual routes and avoiding getting lost. While there is more to learn about how the brain underlies our ability to navigate, neuroscience and psychology have begun to converge on some important answers. In Human Spatial Navigation, four leading expertstackle fundamental and unique issues to produce the first book-length investigation into this subject. Opening with the vivid story of Puluwat sailors who navigate in the open ocean with no mechanical aids, the authors begin by dissecting the behavioral basis of human spatial navigation. They then focus on its neural basis, describing neural recordings, brain imaging experiments, and patient studies. Recent advances give unprecedented insights into what is known about the cognitive map and the neural systems that facilitate navigation. The authors discuss how aging and diseases can impede navigation, and they introduce cutting-edge network models that show how the brain can act as a highly integrated system underlying spatial navigation. Throughout, the authors touch on fascinating examples of able navigators, from the Inuit of northern Canada to London taxi drivers, and they provide a critical lens into previous navigation research, which has primarily focused on other species, such as rodents. An ideal book for students and researchers seeking an accessible introduction to this important topic, Human Spatial Navigation offers a rich look into spatial memory and the neuroscientific foundations for how we make our way in the world.
Human Species: An Introduction to Biological Anthropology Ninth Edition
by John RelethfordIn its ninth edition, The Human Species continues to provide a comprehensive approach to biological anthropology, especially the relationship between biology and culture, behavior in an evolutionary context, and humans as a species within the primate order. With its lively narrative and emphasis on the most current topics and findings in the field, The Human Species explores the major questions that concern biological anthropologists about our species.
The Human Spirit: Beginnings from Genesis to Science
by Marjorie O’Rourke BoyleIn this volume, Marjorie O’Rourke Boyle probes significant concepts of the human spirit in Western religious culture across more than two millennia, from the book of Genesis to early modern science. The Human Spirit treats significant interpretations of human nature as religious in political, philosophical, and physical aspects by tracing its historical subject through the Priestly tradition of the Hebrew Bible and the writings of the apostle Paul among the Corinthians, the innovative theologians Augustine and Aquinas, the reformatory theologian Calvin, and the natural philosopher and physician William Harvey. Boyle analyzes the particular experiences and notions of these influential authors while she contextualizes them in community. She shows how they shared a conviction, although distinctly understood, of the human spirit as endowed by or designed by a divine source of everything animate.An original and erudite work that utilizes a rich and varied array of primary source material, this volume will be of interest to intellectual and cultural historians of religion, philosophy, literature, and medicine.
The Human Spirit: Beginnings from Genesis to Science
by Marjorie O’Rourke BoyleIn this volume, Marjorie O’Rourke Boyle probes significant concepts of the human spirit in Western religious culture across more than two millennia, from the book of Genesis to early modern science. The Human Spirit treats significant interpretations of human nature as religious in political, philosophical, and physical aspects by tracing its historical subject through the Priestly tradition of the Hebrew Bible and the writings of the apostle Paul among the Corinthians, the innovative theologians Augustine and Aquinas, the reformatory theologian Calvin, and the natural philosopher and physician William Harvey. Boyle analyzes the particular experiences and notions of these influential authors while she contextualizes them in community. She shows how they shared a conviction, although distinctly understood, of the human spirit as endowed by or designed by a divine source of everything animate.An original and erudite work that utilizes a rich and varied array of primary source material, this volume will be of interest to intellectual and cultural historians of religion, philosophy, literature, and medicine.
Human Stress and the Environment
by Allen H. RoseFirst published in 1994. This volume is devoted to a study of the relationship between stress and health. The aim of this work is to present an account of this complex and difficult problem, without the sensationalism often associated with modern environmental remedies.
The Human Superorganism: How the Microbiome Is Revolutionizing the Pursuit of a Healthy Life
by Rodney Dietert"Eyeopening... Fascinating... may presage a paradigm shift in medicine." --Kirkus Reviews (starred review)"Teeming with information and big ideas... Outstanding."--Booklist (starred review)The origin of asthma, autism, Alzheimer's, allergies, cancer, heart disease, obesity, and even some kinds of depression is now clear. Award-winning researcher on the microbiome, professor Rodney Dietert presents a new paradigm in human biology that has emerged in the midst of the ongoing global epidemic of noncommunicable diseases. The Human Superorganism makes a sweeping, paradigm-shifting argument. It demolishes two fundamental beliefs that have blinkered all medical thinking until very recently: 1) Humans are better off as pure organisms free of foreign microbes; and 2) the human genome is the key to future medical advances. The microorganisms that we have sought to eliminate have been there for centuries supporting our ancestors. They comprise as much as 90 percent of the cells in and on our bodies--a staggering percentage! More than a thousand species of them live inside us, on our skin, and on our very eyelashes. Yet we have now significantly reduced their power and in doing so have sparked an epidemic of noncommunicable diseases--which now account for 63 percent of all human deaths. Ultimately, this book is not just about microbes; it is about a different way to view humans. The story that Dietert tells of where the new biology comes from, how it works, and the ways in which it affects your life is fascinating, authoritative, and revolutionary. Dietert identifies foods that best serve you, the superorganism; not new fad foods but ancient foods that have made sense for millennia. He explains protective measures against unsafe chemicals and drugs. He offers an empowering self-care guide and the blueprint for a revolution in public health. We are not what we have been taught. Each of us is a superorganism. The best path to a healthy life is through recognizing that profound truth.From the Hardcover edition.
Human Sustainable Cities: Towards the SDGs and Green, Just, Smart and Inclusive Transitions
by Voula MegaThis book argues that accelerating action toward sustainability for and by cities and their inhabitants can make a huge difference to humanity’s endeavor to recover from current crises and build a sustainable future. It sheds light on cutting-edge concepts and actions toward sustainability that can taken by and for cities and with citizens. In this book, author Voula Mega takes the reader on a journey inside and across cities and highlights efforts toward a paradigmatic shift that reconciles human systems with nature. Leadership, education, innovation, trust and citizen empowerment all play a crucial role for the co-invention of a new model that balances human well-being, sustainable prosperity and the future of the planet. Building on robust evidence and inspired by best practices, Human Sustainable Cities offers compelling messages and convincing advice to all stakeholders who are striving to overcome crises, speed up the path toward resilience and preparedness and bounce forward better.
The Human Swarm: How Our Societies Arise, Thrive, and Fall
by Mark W. MoffettThe epic story and ultimate big history of how human society evolved from intimate chimp communities into the sprawling civilizations of a world-dominating species <P><P>If a chimpanzee ventures into the territory of a different group, it will almost certainly be killed. But a New Yorker can fly to Los Angeles--or Borneo--with very little fear. <P><P>Psychologists have done little to explain this: for years, they have held that our biology puts a hard upper limit--about 150 people--on the size of our social groups. But human societies are in fact vastly larger. How do we manage--by and large--to get along with each other? <P><P>In this paradigm-shattering book, biologist Mark W. Moffett draws on findings in psychology, sociology and anthropology to explain the social adaptations that bind societies. He explores how the tension between identity and anonymity defines how societies develop, function, and fail. <P><P>Surpassing Guns, Germs, and Steel and Sapiens, The Human Swarm reveals how mankind created sprawling civilizations of unrivaled complexity--and what it will take to sustain them.
Human Systems Interactions: FOSS Science Resources
by Lawrence Hall of Science University of California at BerkeleyNIMAC-sourced textbook
Human T-Lymphotropic Viruses
by Claudio CasoliWhile HIV-1 continues to be well-researched, this detailed volume draws attention to other members of the Retrovirus family, namely the Human T-lymphotropic Viruses (HTLVs), featuring the most updated technical information about HTLV determination and the methods to investigate their interaction with the host immune system and interfering pathogens. The contents include essential aspects of epidemiology and virus transmission, novel and robust methodologies for studying the effects of trans-activating regulatory HTLVs' proteins, the latest techniques for genotyping and gene expression analysis, as well as cellular phenotype and dynamics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Human T-Lymphotropic Viruses: Methods and Protocols serves as an ideal guide to an area of study that is very much worthy of further research.
Human Temperature Control: A Quantitative Approach
by Eugene H. WisslerThe principal objective of this book is to provide information needed to define human thermal behavior quantitatively. Human thermal physiology is defined using mathematical methods routinely employed by physicists and engineers, but seldom used by physiologists. Major sections of the book are devoted to blood flow, sweating, shivering, heat transfer within the body, and heat and mass transfer from skin and clothing to the environment. Simple algebraic models based on experimental data from a century of physiological investigation are developed for bodily processes. The book offers an invaluable source of information for physiologists and physical scientists interested in quantitative approaches to the fascinating field of human thermoregulation.
Human Tissue in the Realist Novel, 1850-1895 (Palgrave Studies in Literature, Science and Medicine)
by Ben MooreThis Pivot engages with current debates about anthropocentrism and the Anthropocene to propose a reappraisal of the realist novel in the second half of the nineteenth century. Through three case studies, it argues for ‘human tissue’ as a conceptual tool for reading that brings together biology, literature and questions of layering. This new approach is shown to be especially salient to the Victorian period, when the application of ‘tissue’ to biology first emerges. The book is distinctive in bringing together theoretical concerns around realism and the Anthropocene – two major topics in literary criticism – and presenting a new methodology to approach this conjunction, demonstrated through original readings of Charles Kingsley, George Eliot, and Emile Zola and two English-language writers he influenced (George Moore and Vernon Lee).
Human Toxicology of Pesticides (Routledge Revivals)
by Fina P. Kaloyanova M. A. El BatawiFirst Published in 1991, this book conducts a systematic analysis of existing information regarding the toxicological effects of pesticides on humans. The book identifies the negative health effects related to exposure to pesticides and the biological changes required to undertake biological monitoring. The book also discusses the importance and magnitude of the problem for different kinds of pesticide applications in different parts of the world, explains the toxicodynamics and clinical picture of acute and chronic intoxications resulting from exposure to different groups of pesticides and selected individual substances, and evaluates existing methods and limitations for assessing human exposure to pesticides. Pesticide manufacturers, occupational health professionals, epidemiologists, environmentalists, government agencies and others concerned with the effects of pesticides on human populations should consider this book essential reading.