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Applications of Mass Spectrometry in Microbiology: From Strain Characterization to Rapid Screening for Antibiotic Resistance
by Plamen Demirev Todd R. SandrinIn the last quarter century, advances in mass spectrometry (MS) have been at the forefront of efforts to map complex biological systems including the human metabolome, proteome, and microbiome. All of these developments have allowed MS to become a well-established molecular level technology for microorganism characterization. MS has demonstrated its considerable advantage as a rapid, accurate, and cost-effective method for microorganism identification, compared to conventional phenotypic techniques. In the last several years, applications of MS for microorganism characterization in research, clinical microbiology, counter-bioterrorism, food safety, and environmental monitoring have been documented in thousands of publications. Regulatory bodies in Europe, the US, and elsewhere have approved MS-based assays for infectious disease diagnostics. As of mid-2015, more than 3300 commercial MS systems for microorganism identification have been deployed worldwide in hospitals and clinical labs. While previous work has covered broader approaches in using MS to characterize microorganisms at the species level or above, this book focuses on strain-level and subtyping applications. In twelve individual chapters, innovators, leaders and practitioners in the field from around the world have contributed to a comprehensive overview of current and next-generation approaches for MS-based microbial characterization at the subspecies and strain levels. Chapters include up-to-date reference lists as well as web-links to databases, recommended software, and other useful tools. The emergence of new, antibiotic-resistant strains of human or animal pathogens is of extraordinary concern not only to the scientific and medical communities, but to the general public as well. Developments of novel MS-based assays for rapid identification of strains of antibiotic-resistant microorganisms are reviewed in the book as well. Microbiologists, bioanalytical scientists, infectious disease specialists, clinical laboratory and public health practitioners as well as researchers in universities, hospitals, government labs, and the pharmaceutical and biotechnology industries will find this book to be a timely and valuable resource.
Applications of Mathematics and Informatics in Science and Engineering (Springer Optimization and Its Applications #91)
by Nicholas J. DarasAnalysis, assessment, and data management are core competencies for operation research analysts. This volume addresses a number of issues and developed methods for improving those skills. It is an outgrowth of a conference held in April 2013 at the Hellenic Military Academy and brings together a broad variety of mathematical methods and theories with several applications. It discusses directions and pursuits of scientists that pertain to engineering sciences. It is also presents the theoretical background required for algorithms and techniques applied to a large variety of concrete problems. A number of open questions as well as new future areas are also highlighted. This book will appeal to operations research analysts, engineers, community decision makers, academics, the military community, practitioners sharing the current "state-of-the-art," and analysts from coalition partners. Topics covered include Operations Research, Games and Control Theory, Computational Number Theory and Information Security, Scientific Computing and Applications, Statistical Modeling and Applications, Systems of Monitoring and Spatial Analysis.
Applications of Membrane Computing in Systems and Synthetic Biology (Emergence, Complexity and Computation #7)
by Pierluigi Frisco Marian Gheorghe Mario J. Pérez-JiménezMembrane Computing was introduced as a computational paradigm in Natural Computing. The models introduced, called Membrane (or P) Systems, provide a coherent platform to describe and study living cells as computational systems. Membrane Systems have been investigated for their computational aspects and employed to model problems in other fields, like: Computer Science, Linguistics, Biology, Economy, Computer Graphics, Robotics, etc. Their inherent parallelism, heterogeneity and intrinsic versatility allow them to model a broad range of processes and phenomena, being also an efficient means to solve and analyze problems in a novel way. Membrane Computing has been used to model biological systems, becoming with time a thorough modeling paradigm comparable, in its modeling and predicting capabilities, to more established models in this area. This book is the result of the need to collect, in an organic way, different facets of this paradigm. The chapters of this book, together with the web pages accompanying them, present different applications of Membrane Systems to Biology. Deterministic, non-deterministic and stochastic systems paired with different algorithms and methodologies show the full potential of this framework. The book is addressed to researchers interested in applications of discrete biological models and the interplay between Membrane Systems and other approaches to analyze complex systems.
Applications of Metal-Organic Frameworks and Their Derived Materials
by Rajender Boddula Inamuddin Mohd Imran Ahamed Abdullah M. AsiriMetal–organic frameworks (MOFs) are porous crystalline polymers constructed by metal sites and organic building blocks. Since the discovery of MOFs in the 1990s, they have received tremendous research attention for various applications due to their high surface area, controllable morphology, tunable chemical properties, and multifunctionalities, including MOFs as precursors and self-sacrificing templates for synthesizing metal oxides, heteroatom-doped carbons, metal-atoms encapsulated carbons, and others. Thus, awareness and knowledge about MOFs and their derived nanomaterials with conceptual understanding are essential for the advanced material community. This breakthrough new volume aims to explore down-to-earth applications in fields such as biomedical, environmental, energy, and electronics. This book provides an overview of the structural and fundamental properties, synthesis strategies, and versatile applications of MOFs and their derived nanomaterials. It gives an updated and comprehensive account of the research in the field of MOFs and their derived nanomaterials. Whether as a reference for industry professionals and nanotechnologists or for use in the classroom for graduate and postgraduate students, faculty members, and research and development specialists working in the area of inorganic chemistry, materials science, and chemical engineering, this is a must-have for any library.
Applications of Metamaterials (Metamaterials Handbook)
by Filippo CapolinoThis book uses the first volume’s exploration of theory, basic properties, and modeling topics to develop readers’ understanding of applications and devices that are based on artificial materials. It explores a wide range of applications in fields including electronics, telecommunications, sensing, medical instrumentation, and data storage. The text also includes a practical user’s guide and explores key areas in which artificial materials have developed. It includes experts’ perspectives on current and future applications of metamaterials, to present a well-rounded view on state-of-the-art technologies.
Applications of Microfluidic Systems in Biology and Medicine (Bioanalysis #13)
by Manabu TokeshiThis book is the second edition of the one originally published in 2016, which focused on state-of-the-art microfluidic research in medical and biological applications. Similar to the first edition, beginners in the field —undergraduates, engineers, biologists, medical and pharmaceutical researchers—will easily learn to understand microfluidic-based medical and biological applications. Because a wide range of topics is summarized here, it also helps experts to learn more about fields outside their own specialties. In this second edition, significant revisions have been made to chapters covering technologies that have seen major advancements, such as acoustofluidics, protein crystallography, organ-on-a-chip systems, nanopore sensing, and paper-based microfluidics. In addition, the chapters on cancer diagnosis using exosomes and single-cell sequencing using droplet microfluidics, which are attracting attention as new technologies, have been newly added. Readers will be convinced that microfluidic devices have great potential for medical and biological applications.
Applications of Microscopy in Materials and Life Sciences: Proceedings of 12th Asia-Pacific Microscopy Conference (Springer Proceedings in Materials #11)
by Partha Ghosal C. Barry Carter Kutti Ragunath Vinothkumar Rajdeep SarkarThis book comprises the proceedings of the 12th International Conference on Asia-Pacific Microscopy Conference (APMC12) focusing on emerging opportunities and challenges in the field of materials sciences, life sciences and microscopy techniques. The contents of this volume include papers on aberration corrected TEM & STEM, SEM – FIB, ion beam microscopy, electron diffraction & crystallography, microscopy and imaging associated with bio-nanotechnology, medical applications, host-pathogen interaction, etc. This book will be beneficial to researchers, educators, and practitioners alike.
Applications of Modern Heuristic Optimization Methods in Power and Energy Systems (IEEE Press Series on Power Engineering)
by Kwang Y. Lee Zita A. ValeReviews state-of-the-art technologies in modern heuristic optimization techniques and presents case studies showing how they have been applied in complex power and energy systems problems Written by a team of international experts, this book describes the use of metaheuristic applications in the analysis and design of electric power systems. This includes a discussion of optimum energy and commitment of generation (nonrenewable & renewable) and load resources during day-to-day operations and control activities in regulated and competitive market structures, along with transmission and distribution systems. Applications of Modern Heuristic Optimization Methods in Power and Energy Systems begins with an introduction and overview of applications in power and energy systems before moving on to planning and operation, control, and distribution. Further chapters cover the integration of renewable energy and the smart grid and electricity markets. The book finishes with final conclusions drawn by the editors. Applications of Modern Heuristic Optimization Methods in Power and Energy Systems: Explains the application of differential evolution in electric power systems' active power multi-objective optimal dispatch Includes studies of optimization and stability in load frequency control in modern power systems Describes optimal compliance of reactive power requirements in near-shore wind power plants Features contributions from noted experts in the field Ideal for power and energy systems designers, planners, operators, and consultants, Applications of Modern Heuristic Optimization Methods in Power and Energy Systems will also benefit engineers, software developers, researchers, academics, and students.
Applications of Modern Physics in Medicine
by Mark Strikman Kevork Spartalian Milton W. ColeThe connections between modern physics and medical technologyMany remarkable medical technologies, diagnostic tools, and treatment methods have emerged as a result of modern physics discoveries in the last century—including X-rays, radiation treatment, laser surgery, high-resolution ultrasound scans, computerized tomography (CT) scans, and magnetic resonance imaging. This undergraduate-level textbook describes the fundamental physical principles underlying these technological advances, emphasizing their applications to the practice of modern medicine.Intended for science and engineering students with one year of introductory physics background, this textbook presents the medical applications of fundamental principles of physics to students who are considering careers in medical physics, biophysics, medicine, or nuclear engineering. It also serves as an excellent reference for advanced students, as well as medical and health researchers, practitioners, and technicians who are interested in developing the background required to understand the changing landscape of medical science. Practice exercises are included and solutions are available separately in an instructor's manual.Complete discussion of the fundamental physical principles underlying modern medicineAccessible exploration of the physics encountered in a typical visit to a doctorPractice exercises are included and solutions are provided in a separate instructor’s manual (available to professors)A companion website (modernphysicsinmedicine.com) presents supplementary materials
Applications of Monolithic Column and Isotope Dimethylation Labeling in Shotgun Proteome Analysis (Springer Theses)
by Fangjun WangIn this thesis, the author outlines the development of new monolithic columns and isotope dimethyl labeling strategies and their applications in high-performance proteome analyses. Though different types of monolithic columns have been widely developed for chromatography and electrophoresis separation, their application in proteomics for complex peptide mixtures separation is still a challenge. The author discusses the preparation of new monolithic columns and optimization of chromatography separation capability to improve coverage and accuracy of proteome analysis. Further, the author describes a novel online multidimensional chromatography system combined with automated online isotope labeling, which significantly improves the throughput, sensitivity and accuracy of quantitative proteomics. In addition to the development of new technologies, the author investigates the proteome and phosphoproteome expression changes of clinical hepatocellular carcinoma tissues and the hippocampi of mice with Alzheimer's disease. The work in this thesis has led to several publications in high-profile journals in the fields of analytical chemistry and proteome research.
Applications of Nanocomposites
by Ahalapitiya H. JayatissaIn this book, different applications of nanomaterials are described based on experiments, validations, and prototype manufacturing. It also covers synthesis, characterization, functionalization and coating of nanomaterials in various application-oriented investigations. The use of nanomaterials in energy storage, catalyst preparation and tribology are a few examples of improving the efficiency of future technologies. In addition, this book has also contributed to the nanomanufacturing of composites for automobile industries, glass industries, textiles and flexible electronics. This book provides knowledge on multiple related fields in applying nanomaterials, emphasizing the most updated literature, understanding applications, and consists of examples and illustrations so that readers can absorb the content rapidly.
Applications of Nanomaterials for Energy Storage Devices
by Bhaskar Bhattacharya Felipe Caballero-Briones Amit SaxenaElectrochemical energy storage devices are the prime interest of researchers and students. This book provides a comprehensive introduction to nanomaterials and their potential applications specifically for electrochemical devices (rechargeable batteries, supercapacitors and so forth) in a coherent and simple manner. It covers fundamental concepts of nanomaterials, chemical and physical methods of synthesis, properties, characterization methods, and related applications. Features: Introduces the evolution of nanoparticles in electrochemical energy storage devices. Provides the detailed information on step-by-step synthesis of nanoparticles. Discusses different characterization methods (structural, electrical, optical, and thermal). Includes the use of nanoparticles in various electrochemical devices. Aims to bridge the gap between the material synthesis and the real application. This book aims at Senior Undergraduate/Graduate students in Material Chemistry, Electrochemistry and Chemical Engineering, and Energy Storage.
Applications of Nanomaterials in Human Health
by Firdos Alam KhanThis book reviews the various applications of nanotechnology in human health. The introductory chapters focus on the classifications, types, synthesis, and characterization of various types of nanomaterials, while subsequent chapters highlight current applications of nanomaterials in the diagnosis and treatment of microbial and viral infections, and also in stem cell biology and regenerative medicine. Further, the book explores the potential role of nanomaterials in connection with neuronal differentiation, neuronal protection, and neurological diseases. It demonstrates the use of nanotechnology to diagnose and treat genetic disorders, as well as endocrine and metabolic syndrome diseases. It also discusses the ethics and the negative impacts of nanomaterials on human health. Lastly, it examines the intellectual property aspects and government regulations associated with the research, design, and commercialization of nanotechnology-based products. Given its scope, it offers a valuable resource for all researchers and professionals working with nanotechnology-based applications in human health.
Applications of Nanomaterials in Proteomics (Nanostructure Science and Technology)
by Nianrong Sun Chunhui Deng Xizhong ShenThis book provides a comprehensive and systematic overview of the latest advances in nanomaterials for proteomics, both theoretical and practical. Consisting of seven chapters, it first covers the synthesis methods, characterization, principles, and performance of functional nanomaterials in various branches of proteomics in detail. This is followed by the applications of nanomaterials for the separation and analysis of various proteins and peptides. Given its scope, the book appeals to a broad readership, including those active in proteomics and materials science; it can also serve as a reference book for students majoring in proteomics analysis.
Applications of Nanomaterials in Sensors and Diagnostics (Springer Series on Chemical Sensors and Biosensors #14)
by Adisorn TuantranontRecent progress in the synthesis of nanomaterials and our fundamental understanding of their properties has led to significant advances in nanomaterial-based gas, chemical and biological sensors. Leading experts around the world highlight the latest findings on a wide range of nanomaterials including nanoparticles, quantum dots, carbon nanotubes, molecularly imprinted nanostructures or plastibodies, nanometals, DNA-based structures, smart nanomaterials, nanoprobes, magnetic nanomaterials, organic molecules like phthalocyanines and porphyrins, and the most amazing novel nanomaterial, called graphene. Various sensing techniques such as nanoscaled electrochemical detection, functional nanomaterial-amplified optical assays, colorimetry, fluorescence and electrochemiluminescence, as well as biomedical diagnosis applications, e.g. for cancer and bone disease, are thoroughly reviewed and explained in detail. This volume will provide an invaluable source of information for scientists working in the field of nanomaterial-based technology as well as for advanced students in analytical chemistry, biochemistry, electrochemistry, material science, micro- and nanotechnology.
Applications of Nanotechnology for Green Synthesis (Nanotechnology in the Life Sciences)
by Inamuddin Abdullah M. AsiriTraditional methods in synthetic chemistry produce chemical waste and byproducts, yield smaller desired products, and generate toxic chemical substances, but the past two centuries have seen consistent, greener improvements in organic synthesis and transformations. These improvements have contributed to substance handling efficiency by using green-engineered forerunners like sustainable techniques, green processes, eco-friendly catalysis, and have minimized energy consumption, reduced potential waste, improved desired product yields, and avoided toxic organic precursors or solvents in organic synthesis. Green synthesis has the potential to have a major ecological and monetary impact on modern pharmaceutical R&D and organic chemistry fields. This book presents a broad scope of green techniques for medicinal, analytical, environmental, and organic chemistry applications. It presents an accessible overview of new innovations in the field, dissecting the highlights and green chemistry attributes of approaches to green synthesis, and provides cases to exhibit applications to pharmaceutical and organic chemistry. Although daily chemical processes are a major part of the sustainable development of pharmaceuticals and industrial products, the resulting environmental pollution of these processes is of worldwide concern. This edition discusses green chemistry techniques and sustainable processes involved in synthetic organic chemistry, natural products, drug syntheses, as well various useful industrial applications.
Applications of Nanotechnology in Biomedical Engineering
by Piyali Basak Pratik Das Suvendu Manna Tridib Kumar SinhaThis book presents recent advancements in nanotechnology-based innovations in the biomedical sciences and engineering fields, including nanoimaging, nano-delivery of drugs and genes, antimicrobial and antiviral coatings, nano-neutraceuticals, and nano-cosmetics. It covers a wide range of topics, which include nanosensors, nano-based coatings, and wound healing, as well as scope for new research and development. It is a guide to the state-of-the-art nanotechnological advancements in medical image processing and disease detection. Features are as follows: Covers industry-oriented applications of nanomaterials in the field of biomedical engineering Discusses development of nature-inspired nano-engineered nutraceuticals Reviews research on nano-coating to restrict biofilm formation and nosocomial infections Includes different aspects of both medical sciences and health sciences, ranging from medical imaging to cosmetics Explores micro-/nano-SMART devices for biomedical applications This book is aimed at researchers and graduate students in biomedical engineering, nanotechnology, and related areas.
Applications of Nanotechnology in Microbiology
by Ramesh S. Chaughule Anushree S. LokurThis book discusses the applications of nanotechnology in clinical microbiology, food microbiology, and green solutions of nanoparticles using microorganisms for a range of benefits. It describes nanotechnology’s rapid progress in the development of materials used in industry, medicine, drug delivery, and dentistry. The authors further explore how microbiology and nanotechnology separately have proven to be effective for human health solutions keeping an ecological and environmental balance. Domains covered include environmental microbiology, medical microbiology, food microbiology (to control food spoilage), biosynthesis of nanomaterials using microorganisms, water microbiology, nanofluidic devices for isolation and analysis of individual biomolecules such as DNA that can lead to a new detection scheme for cancer, and various fields such as pharmacy, clinical research, agriculture etc. This book will be essential reading to a wide range of scholars and researchers interested in microbiology along with nanotechnology applications for efficient solutions to cancer detection, biosensors, vaccines research, agriculture, wastewater management etc.
Applications of Neutron Scattering to Soft Condensed Matter
by Barbara J. GabrysNeutrons, which are a penetrating yet non destructive probe, are ideally suited to studying the structure, organisation and motion of molecules responsible for the physical properties of materials under a variety of conditions. Applications are in fields as diverse as colloid and polymer science, earth sciences, pharmaceutics, biology and engineeri
Applications of Numerical Methods in Molecular Spectroscopy
by Peter Pelikan Michal Ceppan Marek LiskaApplications of Numerical Methods in Molecular Spectroscopy provides a mathematical background, theoretical perspective, and review of spectral data processing methods. The book discusses methods of complex spectral profile separation into bands, factor analysis methods, methods of quantitative analysis in molecular spectroscopy and reflectance spectroscopy, and new data processing methods. Mathematical methods in special areas of molecular spectroscopy, such as color science, electron spin resonance, and nuclear magnetic resonance spectroscopies are also covered. The book will benefit researchers and postgraduate students in fields of chemistry, physics, and biology.
Applications of Organic and Printed Electronics: A Technology-Enabled Revolution (Integrated Circuits and Systems)
by Eugenio CantatoreOrganic and printed electronics can enable a revolution in the applications of electronics and this book offers readers an overview of the state-of-the-art in this rapidly evolving domain. The potentially low cost, compatibility with flexible substrates and the wealth of devices that characterize organic and printed electronics will make possible applications that go far beyond the well-known displays made with large-area silicon electronics. Since organic electronics are still in their early stage, undergoing transition from lab-scale and prototype activities to production, this book serves as a valuable snapshot of the current landscape of the different devices enabled by this technology, reviewing all applications that are developing and those can be foreseen.
Applications of Palaeontology: Techniques and Case Studies
by Robert Wynn JonesPalaeontology, the scientific study of fossils, has developed from a descriptive science to an analytical science used to interpret relationships between earth and life history. This book provides a comprehensive and thematic treatment of applied palaeontology, covering the use of fossils in the ordering of rocks in time and in space, in biostratigraphy, palaeobiology and sequence stratigraphy. Robert Wynn Jones presents a practical workflow for applied palaeontology, including sample acquisition, preparation and analysis, and interpretation and integration. He then presents numerous case studies that demonstrate the applicability and value of the subject to areas such as petroleum, mineral and coal exploration and exploitation, engineering geology and environmental science. Specialist applications outside of the geosciences (including archaeology, forensic science, medical palynology, entomopalynology and melissopalynology) are also addressed. Abundantly illustrated and referenced, Applications of Palaeontology provides a user-friendly reference for academic researchers and professionals across a range of disciplines and industry settings.
Applications of Palaeontology
by Robert Wynn JonesPalaeontology, the scientific study of fossils, has developed from a descriptive science to an analytical science used to interpret relationships between earth and life history. This book provides a comprehensive and thematic treatment of applied palaeontology, covering the use of fossils in the ordering of rocks in time and in space, in biostratigraphy, palaeobiology and sequence stratigraphy. Robert Wynn Jones presents a practical workflow for applied palaeontology, including sample acquisition, preparation and analysis, and interpretation and integration. He then presents numerous case studies that demonstrate the applicability and value of the subject to areas such as petroleum, mineral and coal exploration and exploitation, engineering geology and environmental science. Specialist applications outside of the geosciences (including archaeology, forensic science, medical palynology, entomopalynology and melissopalynology) are also addressed. Abundantly illustrated and referenced, Applications of Palaeontology provides a user-friendly reference for academic researchers and professionals across a range of disciplines and industry settings.
Applications of Paleoenvironmental Techniques in Estuarine Studies (Developments in Paleoenvironmental Research #Volume 20)
by Kaarina Weckström Krystyna M. Saunders Peter A. Gell C. Gregory SkilbeckThe aim of this edited volume is to introduce the scientific community to paleoenvironmental studies of estuaries, to highlight the types of information that can be obtained from such studies, and to promote the use of paleoenvironmental studies in estuarine management. <P><P> Readers will learn about the the application of different paleoecological approaches used in estuaries that develop our understanding of their response to natural and human influences. Particular attention is given to the essential steps required for undertaking a paleoecological study, in particular with regard to site selection, core extraction and chronological techniques, followed by the range of indicators that can be used. A series of case studies are discussed in the book to demonstrate how paleoecological studies can be used to address key questions, and to sustainably manage these important coastal environments in the future. This book will appeal to professional scientists interested in estuarine studies and/or paleoenvironmental research, as well as estuarine managers who are interested in the incorporation of paleoenvironmental research into their management programs.
Applications of Palynology in Stratigraphy and Climate Studies (Society of Earth Scientists Series)
by Bandana Samant Deepali ThakreThis book highlights the importance of palynology in understanding floral biodiversity, paleoclimate and depositional environments in deep time and recent sediments. It includes contributions from renowned Indian palynologists who work on the applied aspects of palynology. The book focuses on the significance of palynology in solving various geological problems, ranging from the Precambrian to the Recent. This book will be useful to graduate and postgraduate students, researchers, and academicians working in geology and botany, as well as international researchers interested in palynological research work in India.