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Lung Inflammation in Health and Disease, Volume II (Advances in Experimental Medicine and Biology #1304)
by Yong-Xiao WangLung diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma. Each year, tens of millions of people develop and can die from lung infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for some patients. Current treatment options for lung disease are neither always effective, nor condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases is not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung disease, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, and students with new perspectives and concepts. The editors hope these books will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.
Lung Innate Immunity and Inflammation: Methods and Protocols (Methods in Molecular Biology #1809)
by Scott Alper William J. JanssenThis detailed book explores methods to isolate, characterize, and investigate key lung innate immune cells. Beginning with an overview, the volume then continues with methods for creating in vitro and in vivo model systems to study inflammatory lung diseases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Lung Innate Immunity and Inflammation: Methods and Protocols aims to be a guidebook and will be of value and interest to researchers investigating innate immunity and inflammation in the lung as well as other organs and tissues.
Lung Stem Cell Behavior
by Ahmed El-HashashThis book reviews stem cell behavior in the lung as it relates to regenerative medicine and stem cell therapeutics. Topics ranging from basic developmental mechanisms of various types of lung stem cells through the identification and properties of stem cell behavior and their potential applications in lung repair and regeneration, are discussed by an expert in the field. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in understanding of developmental lung stem cell biology and behavior and their potential applications. Lung Stem Cell Behavior is essential reading for researchers in stem cell biology and regenerative medicine, patient advocates, undergraduate students, graduate students, and clinicians interested in cellular therapy and tissue engineering therapies.
Lung Stem Cells in the Epithelium and Vasculature
by Amy Firth Jason X.-J. YuanThis book covers the identification and role of endogenous lung stem cells in health and disease, particularly the most recent advances. In addition, it discusses the rapidly growing field of stem cells and cell therapy as it relates to lung biology and disease as well as ex vivo lung bioengineering. Such approaches may provide novel therapeutic approaches for lung diseases. Human pluripotent stem cell differentiation to model the pulmonary epithelium and vasculature is also discussed. World-recognized scientists who specialize in studying both the lung epithelium and pulmonary vasculature contribute the chapters. Topics covered include: stem cell niches in the lung, the role of progenitor cells in fibrosis and asthma, iPSC in modeling lung disease, vascular repair by endothelial progenitor cells and circulating fibrocytes in pulmonary vascular remodeling. This volume of the Stem Cell Biology and Regenerative Medicine series is essential reading for researchers and clinicians interested in stem cells, lung biology and regenerative medicine. It is also an invaluable resource for advanced students studying cell biology, regenerative medicine and lung physiology.
Lung Surfactants: Basic Science and Clinical Applications (Lung Biology in Health and Disease)
by Knud Erik SkoubyIntegrating basic and clinical research on the biophysical and physiological functions of pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on surfactant-related lung disease. Manage neonatal respiratory distress syndrome (RDS), acute respiratory distress syndrome (ARDS), and acute lung injury more effecti
The Lupin Genome (Compendium of Plant Genomes)
by Karam B. Singh Lars G. Kamphuis Matthew N. NelsonThis book on lupin genomics primarily focuses on the narrow-leafed lupin (NLL), and details the genomic resources that have been developed and how they are currently being used to help advance both fundamental and applied research on NLL in areas ranging from its domestication to plant–microbe interactions and syntenic relationships between NLL and other legume crops. It also reports on genomic efforts being pursued with regard to other lupin crops.Lupins are important ecological ‘engineers’: they can colonise and thrive in low-nutrient soils due to their ability to fix atmospheric nitrogen in symbiosis with bacteria and efficiently take up phosphorous. Recently, lupins have attracted considerable interest, not only because of their value for sustainable farming as a break crop, but also as a potential ‘super food’ for fighting major health issues in connection with diabetes and obesity.Narrow-leafed lupin is the main grain legume crop, grown primarily in Australia, and was therefore selected for the development of a reference lupin genome and associated genomic resources. Its genome has recently been sequenced with a focus on the gene-rich space, which has advanced the development of new breeding tools for the improvement of NLL and related lupin crops.
Lupus The Facts
by Graham HughesThis easy-to-read book explains Lupus. How does Lupus affect people? What can be done if someone develops lupus?
Lust und Liebe - alles nur Chemie? (Erlebnis Wissenschaft)
by Gabriele Froböse Rolf FroböseHinter dem Titel des Bandes verbirgt sich mehr als bloß die Analyse von Aphrodisiaka oder Potenzmitteln. Großhirnrinde, Hypophyse oder körpereigene Opiate: Sie alle sind beteiligt, wenn Verliebte sich küssen oder ein junger Mann seinem ersten Rendezvous entgegenfiebert. Dieses unterhaltsame Buch wirft einen Blick hinter die molekularen Kulissen des aufregendsten aller Gefühle. Die Liebe schlägt nicht nur Verliebte in ihren Bann. Dass auch Chemiker manch faszinierende Erkenntnis zu diesem Phänomen vermitteln können, belegt dieses Buch eindrucksvoll. Ihren wissenschaftlichen Streifzug durch Amors Reich beginnt das Autorenduo (das übrigens auch ein Autorenpaar ist) mit einer Geschichte: Zwei Verliebte treffen sich wieder, nachdem sie sich eine Weile nicht gesehen haben. Was geschieht in ihren Köpfen? Wie lassen sich ihre Verhaltensweisen und Reaktionen chemisch beschreiben? Im Anschluss widmen sich die beiden Wissenschaftsjournalisten ausführlich der "Mentalität" der Liebe: Sie gehen der Frage nach, wie sie im menschlichen Gehirn repräsentiert wird. Auch den "Dialog der Düfte" entschlüsseln sie und fragen nach den physiologischen Hintergründen von Zärtlichkeit und Treue. Sie erklären, wie Moleküle unsere Emotionen steuern, und belegen, dass sich Verliebte wirklich gut "riechen" können. Nicht nur Chemiker dürfte interessieren, was das Buch über die "Wirkstoffe der Liebe" zu berichten weiß. Mal ergründet es die Funktionsweise körpereigener Opiate, dann wenden sich die Autoren den Aphrodisiaka zu oder referieren den Stand der Dinge in Sachen Potenzmittel. Die Fortsetzung der kleinen Liebesgeschichte vom Anfang sowie ein Sach- und Personenregister beschließen den Band.
La luz en la oscuridad: Los agujeros negros, el universo y nosotros
by Heino FalckeUn viaje extraordinario a los límites del tiempo, el espacio y la mente humana, de la mano de Heino Falcke, galardonado con la Medalla Henry Draper 2021. El 10 de abril de 2019 un equipo internacional de astrónomos liderados por el profesor Heino Falcke maravilló al mundo publicando la primera imagen de un agujero negro. Por fin la comunidad científica conseguía la prueba irrefutable de lo que Einstein había predicho en su teoría de la relatividad acerca de estos fenómenos hacía más de cien años. Sin embargo, las implicaciones de este hallazgo van más allá: si bien son objetos relativamente simples de definir, los agujeros negros plantean algunos de los interrogantes más complejos sobre la naturaleza del espacio, del tiempo, y, por último, de nuestra existencia. En este libro, Falcke no solo nos narra la emocionante historia de esta proeza científica, sino que da un paso más intentando responder a las grandes preguntas filosóficas que este hito plantea: ¿existe algo más allá de la nada?, ¿puede la ciencia explicar lo inexplicable?, ¿cuál es el origen de nuestra existencia y qué sentido tiene nuestro paso por el mundo? Para Heino Falcke, la astrofísica y la metafísica, la razón y la fe, no tienen por qué excluirse mutuamente. La luz en la oscuridad es un poderoso alegato a favor de la ciencia que nos habla de lo que sabemos pero también de los misterios que quedan por resolver.
La luz revelada: Del telescopio de Galileo a la extrañeza cuántica
by Serge HarocheCómo la luz iluminó nuestra comprensión del universo,por el premio Nobel de Física Serge Haroche. ¿Qué es la luz, ese fenómeno que ha iluminado y fascinado a la humanidad desde el principio de los tiempos? Serge Haroche traza el panorama de lo que sabemos hoy sobre ella, cómo lo aprendimos y hasta qué punto todo ello revolucionó nuestra vida. Al rastrear la historia de la ciencia de la luz desde Galileo hasta nuestros días, Haroche nos enseña también cómo nació la teoría de la relatividad y de dónde proviene la física cuántica. Revive desde dentro, como teórico y experimentador, esta fascinante aventura científica trazando reveladoras conexiones entre la óptica, la mecánica, la electricidad y el magnetismo, para mostrarnos el papel esencial que ha desempeñado la luz en el nacimiento de la física moderna y en nuestra representación del universo.
Lyapunov Functionals and Stability of Stochastic Functional Differential Equations
by Leonid ShaikhetStability conditions for functional differential equations can be obtained using Lyapunov functionals. Lyapunov Functionals and Stability of Stochastic Functional Differential Equations describes the general method of construction of Lyapunov functionals to investigate the stability of differential equations with delays. This work continues and complements the author's previous book Lyapunov Functionals and Stability of Stochastic Difference Equations, where this method is described for difference equations with discrete and continuous time. The text begins with both a description and a delineation of the peculiarities of deterministic and stochastic functional differential equations. There follows basic definitions for stability theory of stochastic hereditary systems, and the formal procedure of Lyapunov functionals construction is presented. Stability investigation is conducted for stochastic linear and nonlinear differential equations with constant and distributed delays. The proposed method is used for stability investigation of different mathematical models such as: * inverted controlled pendulum; * Nicholson's blowflies equation; * predator-prey relationships; * epidemic development; and * mathematical models that describe human behaviours related to addictions and obesity. Lyapunov Functionals and Stability of Stochastic Functional Differential Equations is primarily addressed to experts in stability theory but will also be of interest to professionals and students in pure and computational mathematics, physics, engineering, medicine, and biology.
Lyapunov Stability of Transformation Semigroups (Latin American Mathematics Series)
by Victor H. Rocha Josiney A. SouzaThis book presents recent research results on Lyapunov stability and attraction for semigroup actions in a pedagogical format, providing the reader with numerous modern ideas and mathematical formulations for dynamical concepts in the transformation group theory. In recent decades, many fundamental concepts of dynamical systems have been extended to the general framework of transformation semigroups. Limit sets, attractors, isolated invariant sets, prolongational limit sets, and stable sets now have semigroup theoretical analogues. This monograph consolidates recent advancements in this field in a way that makes it accessible to graduate students. An effort was made to relate the presented results to important recurrence notions, for contextual clarity. A rudimentary understanding of group theory and topology, including the concepts of semigroup action, orbit, fiber bundle, compactness, and connectedness, is a prerequisite for reading this text. As a valuable resource for research projects and academic dissertations on topological dynamics, geometry, and mathematical analysis, this work can potentially open new avenues for further research.
The Lychee Biotechnology
by Manoj Kumar Vivek Kumar Ram Prasad Ajit VarmaThis book provides systematic information on the lychee and modern tools to promote its sustainable growth and development. Including dedicated chapters on the evolution and diversification of the lychee, it highlights its genetic makeup and reciprocal exogenous factors, addressing the narrow genetic pool and lack of natural biodiversity. It also discusses issues related to post-harvest losses and robust approaches at the commercial level. Further, the book offers insights on in vitro propagation methods and prospective transgenic approaches for selected lychee cultivars. Chapters on the production of bioactive compounds and their enhancement through genetic transformation and elicitation are also included, reflecting the latest advances in the field of lychee biotechnology. Lastly, the book explores the use of molecular marker techniques to achieve the desired improvements in fruit trees' medicinal and aesthetic value.
Lycium Barbarum and Human Health
by Raymond Chuen-Chung Chang Kwok-Fai SoThis book seeks to unravel the mysteries of wolfberry, and systematically introduces its mechanisms in preventing aging-associated diseases, such as cardiovascular diseases, inflammation, liver and neurodegenerative diseases. Wolfberry, the dried fruit of Lycium barbarum, is an anti-aging herbal medicine. There have been numerous reports investigating the underlying mechanisms of its anti-aging effects and its role in preventing pathological changes in many aging-associated diseases. Its holistic effects on the body can attenuate liver toxicity and combat the spread of cancer; it also prevents degeneration in the central nervous system, and can even positively affect the skin. As such, wolfberry has become a very popular food supplement around the world. This book will serve as an excellent reference source for researchers and graduate students studying herbal medicine and aging-associated diseases, while also providing insights for the pharmaceutical industry with regard to developing potential drugs for these diseases.
Lycopene: Nutritional, Medicinal and Therapeutic Properties
by Victor R. Preedy Ronald R. WatsonTomatoes have become a dietary staple for humans in many parts of the world. The characteristic deep red color of the ripe tomato fruit and related products is mainly due to lycopene. Lycopene is the predominant carotenoid in tomatoes, followed by a-carotene, b-carotene, g-carotene, and phytoene, as well as by several other minor carotenoids. Tomat
Lyman-alpha as an Astrophysical and Cosmological Tool: Saas-Fee Advanced Course 46. Swiss Society for Astrophysics and Astronomy (Saas-Fee Advanced Course #46)
by Matthew Hayes Mark Dijkstra J. Xavier Prochaska Masami OuchiThe hydrogen Lyman-alpha line is of utmost importance to many fields of astrophysics. This UV line being conveniently redshifted with distance to the visible and even near infrared wavelength ranges, it is observable from the ground, and provides the main observational window on the formation and evolution of high redshift galaxies. Absorbing systems that would otherwise go unnoticed are revealed through the Lyman-alpha forest, Lyman-limit, and damped Lyman-alpha systems, tracing the distribution of baryonic matter on large scales, and its chemical enrichment.We are living an exciting epoch with the advent of new instruments and facilities, on board of satellites and on the ground. Wide field and very sensitive integral field spectrographs are becoming available on the ground, such as MUSE at the ESO VLT. The giant E-ELT and TMT telescopes will foster a quantum leap in sensitivity and both spatial and spectroscopic resolution, to the point of being able, perhaps, to measure directly the acceleration of the Hubble flow. In space, the JWST will open new possibilities to study the Lyman-alpha emission of primordial galaxies in the near infrared. As long as the Hubble Space Telescope will remain available, the UV-restframe properties of nearby galaxies will be accessible to our knowledge. Therefore, this Saas-Fee course appears very timely and should meet the interest of many young researchers.
Lyme Disease: Why It’s Spreading, How It Makes You Sick, and What to Do about It (A Johns Hopkins Press Health Book)
by Alan G. BarbourA world-renowned Lyme disease expert explains everything you need to know if you live, work, or play in areas with the ticks that carry disease.Once restricted to small forested areas in the northeast and north-central United States, Lyme disease is now a common infection in North America and Europe. The Centers for Disease Control and Prevention estimate that more than 300,000 new cases occur each year in the United States. Misunderstandings over symptoms and treatment increase the public's concerns about the disease—which, if not properly treated, can become chronic and debilitating. An expert on tick-borne diseases, Alan G. Barbour explains the course of illness that results from infection, diagnosis and treatment options, and steps that can be taken to avoid a tick bite in the first place. The ticks that transmit Lyme disease may also transmit other disease-causing pathogens, and these other infections are considered as well. Drawing on real case histories of individuals with Lyme disease—or illnesses that may be mistaken for Lyme disease—Barbour explains: The biology of the spirochete, Borrelia burgdorferi, that causes Lyme disease The role of animals such as mice that carry the infection The life cycle of the ticks that transmit the infection The importance of deer in perpetuating the cycle The basics of diagnostic laboratory tests and how test results are interpreted How antibiotics are used in treating Lyme diseaseInfected ticks are abundant in the woods, in walking trails, and in the shrubs and tall grass where suburban lawns meet wooded areas. Barbour stresses preventing disease through community-wide ecology projects and individual and household protection. While it may be difficult to escape infection, understanding the danger, the symptoms, and the treatment goes a long way toward preventing long-term health consequences. Featuring a list of reliable web sites and a glossary of terms, Lyme Disease is an invaluable resource for everyone who is at risk of the disease or is involved in preventing and treating it.
The Lymnaeidae: A Handbook on Their Natural History and Parasitological Significance (Zoological Monographs #7)
by Maxim V. Vinarski Antonio A. VázquezThe Lymnaeidae (also known as ‘pond snails’) are a species-rich and globally distributed family of freshwater snails, many species of which are known to be hosts of parasitic trematodes (such as the liver fluke, Fasciola hepatica). Written by world-leading experts in the field, this book covers a wealth of topics ranging from the phylogeny and taxonomy of lymnaeid snails to their relationships with helminths and their impact on public and veterinary health. It provides an overview of the species richness, evolution, ecology, biogeography and fossil record of the family. A considerable number of chapters are devoted to the economic and medical importance of lymnaeids, their involvement in the transmission of fascioliasis and other zoonotic diseases. Special chapters deal with the molecular and morphological identification of the Lymnaeidae, their rearing in the laboratory and experimental approaches to their study. This contributed volume is aimed at experts and practitioners in various disciplines: Invertebrate zoology, evolutionary biology, biogeography, aquatic ecology, parasitology, epidemiology and public health. It is also useful for university lecturers, undergraduate and postgraduate students.
LYMPH & LONGEVITY: The Untapped Secret to Health
by Dr Gerald M LemoleThe lymphatic system has been one of the most misunderstood systems in our bodies. Until now.Cardiothoracic surgeon Dr. Gerald M. Lemole explains why a healthy lymphatic flow aids our bodies in reducing toxins that contribute to disease and injury. In ten short chapters, Dr. Lemole demystifies the lymphatic system, describes how powerful it is and shows how to maintain a healthy lymph system to combat specific diseases and health problems - from heart disease to cognitive function to weight management.Featuring sidebars with charts and graphs that illustrate basic principles, Lymph & Longevity also includes menus, recipes and information on supplements, as well as basic yoga and meditation guides.Illuminating, informative, and practical this essential guide is timelier now than ever as we continue to work to protect ourselves and our communities against COVID-19 and other viruses.
Lymph & Longevity: The Untapped Secret to Health
by M.D. Gerald LemoleLearn how you can boost your immune system and help prevent virtually every major medical condition—including cancer, heart disease, neurological disorders, GI issues, and obesity—by keeping your lymph system healthy, as explained by renowned cardiologist Gerald Lemole.The lymphatic system serves as our body&’s maintenance department and has a direct effect on our cardiovascular, neurological, and immune systems. It has also been one of the most misunderstood systems. Until now. At last, renowned cardiothoracic surgeon and pioneer in the study of lymph Gerald Lemole explains in straightforward language why the lymphatic system is the key factor in longevity and disease prevention, and how improving lymphatic flow can help our bodies eliminate the toxins and waste products that contribute to injury, inflammation, and disease. In ten short chapters he demystifies the lymphatic system, describes how powerful it is, and shows how to maintain a healthy lymph system to combat specific diseases and health problems—from heart disease to cognitive function to weight management. Featuring sidebars with charts and graphs that illustrate basic principles, Lymph & Longevity also includes flow-friendly menus, recipes, and information on supplements, as well as basic yoga and meditation guides. Illuminating, informative, and practical this essential guide is more timely now than ever as we continue to work to protect ourselves and our communities against Covid-19 and other viruses.
Lymphangiogenesis: Methods and Protocols (Methods in Molecular Biology #1846)
by Guillermo Oliver Mark L. KahnThis volume discusses the latest tools, techniques, and animal models designed to study the processes of lymphatic vascular formation in vivo and in vitro and its functions in health and disease. The chapters in the book cover topics such as genetics lineage tracing of lymphatic endothelial cells in mice; characterization of zebrafish facial lymphatics; imaging lymphatics in mouse lungs; effects of fluid shear stress of lymphatic endothelial cells; and single cell mRNA sequencing of the mouse brain vasculature. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Lymphangiogenesis: Methods and Protocols is a valuable resource to aid researchers with applying new approaches to answer their questions in this developing field.
Lymphatic Transport of Drugs
by William N. CharmanLymphatic Transport of Drugs provides a thorough review of the determinants that affect the uptake and delivery of drugs and xenobiotics to the lymphatics. Factors affecting the transport and delivery of lipophilic drugs through the lymph after oral administration, lymphatic transport of polar drugs and macromolecules after gastrointestinal dosing, transport of drugs into the lymph after parenteral administration, and particulate drug delivery systems are among the topics examined in this volume. Lymphatic Transport of Drugs is primarily intended for pharmaceutical scientists who are attempting to alter the delivery of current therapeutic agents through formulation of prodrugs, as well as for researchers designing new drugs for lymph delivery.
Lymphocyte Immunization Therapy (LIT) in Reproductive Failures: New Horizons
by Mohan Raut Mugdha RautRecurrent Miscarriages (RM) & Implantation Failure (IF) have remained an enigma to clinicians and researchers. Even after ruling out all possible causative factors, 50-60% cases still remain “Unexplained’. A majority of these so called “Unexplained” cases are now found to have immunological basis.This book is going into the Immunological aspects of these clinical dilemmas, demystifying the role of Immunology and Immunotherapy in RM and IF. The authors have been working in the field of Reproductive Immunology and Immunotherapy for the last 25 years and they have come out with this book combining the international studies with their own experience. The purpose of writing this book is to provide a comprehensive treatise about Immunotherapy, so that it can become an acceptable modality of treatment in cases where it is needed and is effective.The book discusses the basics in Reproductive Immunology. The immunological changes occurring during pregnancy, the role of Cell mediated Immunity (T cells), Humoral Immunity including cytokines is explained. The normal immunological mechanisms protecting the embryo are highlighted and how these mechanisms are disturbed leading to RM and IF, is also explained.The first and the most discussed method of Immunotherapy is Lymphocyte Immunization Therapy (LIT). The book has given a complete overview of LIT, describing how it created euphoria when it was first introduced, how it gradually went into disrepute and how it is now making a comeback. As the authors have personal experience of LIT, the book gives a detailed and complete information about this active form of immunotherapy.The book has a special section on case studies where the authors have given some clinical case reports (including some of their own), who were treated for immunological factor in RM/IF and were treated with Immunotherapy. These cases can be a useful guide to the readers.The book will be useful not only for undergraduate and postgraduate students but also for clinicians in their practice and for researchers for review of developments in the field.
Lymphoma: Methods and Protocols (Methods in Molecular Biology #2865)
by Ralf KüppersThis detailed volume expands upon the previous edition with key methods currently used in lymphoma research, partly specific for lymphoma research but often adaptable to the study of other cancers. New chapters explore the latest approaches for single cell B cell and T cell receptor sequencing, multiplexed immunophenotyping of lymphoma tissue samples, genetic manipulation and extended culture of human germinal center B cells, genetic mouse models of lymphomas, establishment of patient-derived xenograft models of lymphomas, and more. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-day, Lymphoma: Methods and Protocols, Third Edition serves as a valuable resource for hematologists, hematopathologists, and scientists interested in a variety of topics in cancer research, human genetics, and immunology.
Lymphoma
by Robert Marcus John W. Sweetenham Michael E. Williams Robert Marcus John W. SweetenhamMajor advances have occurred in the diagnosis and treatment of lymphoma in recent years. Our understanding of the molecular biology and genetics of the disease has increased exponentially, and significant imaging developments have resulted in earlier and more accurate diagnosis. The new edition of this landmark text places these advances in the context of daily clinical practice. Each chapter has been updated to reflect recent developments, including new treatment agents such as immunomodulatory drugs and the next generation of antibodies, and the increasing prognostic role of PET scanning. Results from recent large-scale clinical trials are presented, and pathology and cytogenetics are integrated into discussion of each disease entity, enabling the reader to review all the key diagnostic information in one place. Featuring many color illustrations, and written and edited by leading authorities in the field, Lymphoma provides all the information you need to diagnose and manage these complex disorders.