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Applied Metallomics: From Life Sciences to Environmental Sciences
by Yu-Feng Li Hongzhe SunApplied Metallomics A groundbreaking survey of a field that unites the sciences The metallome of a cellular compartment, such as an enzyme, is the variety and arrangement of its metal ions. Metallomics is the multidisciplinary study of the metallome and its many important interactions with biological molecules and systems. It exists at the intersection of biochemistry and materials science, offering crucial insights into biological processes in which iron, for instance, plays a pivotal role. Applied Metallomics is an up-to-the-minute overview of research developments in metallomics, offering both analysis and applications in a vast array of scientific and industrial areas. Moving freely between material science, environmental science, health science, and more, it offers a comprehensive survey of this interdisciplinary research area. As the field of metallomics continues to develop and its applications expand, this book will only be a need of the hour Applied Metallomics readers will also find: Detailed treatment of nanometallomics, environmetallomics, agrometallomics, and many more Coverage of machine learning and artificial intelligence techniques with applications in metallomics An author team with vast international research experiences Applied Metallomics is ideal for researchers in many areas touched by metallomics, that include chemistry, biochemistry, biotechnology, bioinorganic chemistry, and more.
Applied Metallurgy and Corrosion Control: A Handbook for the Petrochemical Industry (Indian Institute of Metals Series)
by Amiya Kumar LahiriThis book serves as a comprehensive resource on metals and materials selection for the petrochemical industrial sector. The petrochemical industry involves large scale investments, and to maintain profitability the plants are to be operated with minimum downtime and failure of equipment, which can also cause safety hazards. To achieve this objective proper selection of materials, corrosion control, and good engineering practices must be followed in both the design and the operation of plants. Engineers and professional of different disciplines involved in these activities are required to have some basic understanding of metallurgy and corrosion. This book is written with the objective of servings as a one-stop shop for these engineering professionals. The book first covers different metallic materials and their properties, metal forming processes, welding, and corrosion and corrosion control measures. This is followed by considerations in material selection and corrosion control in three major industrial sectors, oil & gas production, oil refinery, and fertilizers. The importance of pressure vessel codes as well as inspection and maintenance repair practices have also been highlighted. The book will be useful for technicians and entry level engineers in these industrial sectors. Additionally, the book may also be used as primary or secondary reading for graduate and professional coursework.
Applied Methods for Agriculture and Natural Resource Management: A Festschrift in Honor of Richard E. Howitt (Natural Resource Management and Policy #50)
by Siwa Msangi Duncan MacEwanThis book assesses recent developments in the analysis of agricultural policy and water resource management, and highlights the utility and theoretical rigor of quantitative methods for modeling agricultural production, market dynamics, and natural resource management. In diverse case studies of the intersection between agriculture, environmental quality and natural resource sustainability, the authors analyze economic behavior - both at aggregate as well as at individual agent-level - in order to highlight the practical implications for decision-markers dealing with environmental and agricultural policy. The volume also addresses the challenges of doing robust analysis with limited data, and discusses the appropriate empirical approaches that can be employed. The studies in this book were inspired by the work of Richard E. Howitt, Emeritus Professor of Agricultural Economics at the University of California at Davis, USA, whose career has focused on the application of robust empirical methods to address concrete policy problems.
Applied Microbiology
by Sanjai SaxenaThe book is oriented towards undergraduates science and engineering students; postgraduates and researchers pursuing the field of microbiology, biotechnology, chemical - biochemical engineering and pharmacy. Various applications of microorganisms have been covered broadly and have been appropriately reflected in depth in 12 different chapters. The book begins with an insight to the diverse niche of microorganisms which have been explored and exploited in development of various biotechnological products and green processes. Further, how these microorganisms have been genetically modified to improve the desired traits for achieving optimal production of microbially derived products is discussed in the second chapter. Major route of production of microbially derived products and processes is through fermentation technology and therefore due emphasis on different aspects of fermentation technology has been given in the subsequent chapter. The development and deployment of biopesticides and biofertilizers which find tremendous application have been separately discussed under agricultural applications. Application of microbes for the removal of pollutants, recovery of metals and oils has also been discussed under environmental applications. The role of microbial systems in development of fermented foods and beverages have also been discussed in Chapter 6. The application of microbes in production of commodity chemicals and fine chemicals has also been discussed in separate chapters. A chapter has been dedicated to the tremendous applications of microbially produced enzymes in different industrial sectors. Another unique facet of this book is explaining the different methods by which desired traits of microorganisms have been improved for their efficacious and economical exploitation in the industry. A chapter is dedicated to exploitation of microorganisms in development of vaccines for human and veterinary use. Finally, the last chapter discusses the role of immobilization in optimization of industrial processes and development of microbial biosensors for industrial applications. Thus, this book is a holistic approach providing information on the present applications of microorganisms.
Applied Microbiology and Molecular Biology in Oilfield Systems: Proceedings from the International Symposium on Applied Microbiology and Molecular Biology in Oil Systems (ISMOS-2), 2009
by Torben Lund Skovhus Corinne WhitbyApplied Microbiology and Molecular Biology in Oil Field Systems addresses the major problems microbes cause in oil fields, (e.g. biocorrosion and souring) and how beneficial microbial activities may be exploited (e.g. MEOR and biofuels). The book describes theoretical and practical approaches to specific Molecular Microbiological Methods (MMM), and is written by leading authorities in the field from both academia and industry. The book describes how MMM can be applied to faciliate better management of oil reservoirs and downstream processes. The book is innovative in that it utilises real industrial case studies which gives useful technical and scientific information to researchers, engineers and microbiologists working with oil, gas and petroleum systems.
Applied Microbiology in Intensive Care Medicine
by Nissar Shaikh Arshad Hussain ChandaThis book covers microbiological features of the diseases that require intensive care support, including iatrogenic and hospital-acquired infections. The knowledge will assist in the early diagnosis and treatment of bacterial, viral, and fungal infections requiring critical care admission to improve patient outcomes. All microbiological and therapeutic concerns and management of infectious disorders of all human body systems, from the brain to the musculoskeletal system, are addressed. It also describes practical and descriptive ways to prevent, diagnose, and manage various known and forthcoming healthcare-associated illnesses, ranging from MRSA to VRE and others. Applied Microbiology in Intensive Care Medicine will benefit not only intensive and critical care practitioners but also infectious disease practitioners and physicians, surgeons, intensivists, clinical pharmacists, nurses, and technicians in intensive care units.
Applied Microphotonics (Optical Science and Engineering)
by Wes R. Jamroz Roman Kruzelecky Emile I. HaddadAs the limits of electrical performance come within sight, photons are poised to take over for the electron. But the search continues for the materials, topologies, and fabrication technologies capable of producing photonic devices at a reasonable speed and cost. Taking a fundamentallook at the development of photonic technology from the macro- to the microscale, Applied Microphotonics introduces the major principles and technologies underlying the field.Following an overview of historical and commercial driving forces, the authors briefly review the underlying physics, emphasizing the practical and design implications for photonic systems. This general discussion lays the foundation for the remainder of the book, where the authors first introduce the photonic node and then discuss each subsystem in detail, including transmitters, couplers and switches, multiplexers and demultiplexers, receivers, amplifiers, and compensators. The following chapters explore new technologies such as photonic band gap structures, materials and fabrication processes, integration methodologies, and advanced devices such as photonic computers. The book concludes with a brief introduction to quantum photonics and a forward look at potential directions of photonics. Applied Microphotonics encapsulates the recent push toward all-optical networks and devices with an applications-oriented perspective. It is ideal for newcomers to the field as well as anyone curious to know how photonic technology can benefit their own field.
Applied Molecular Biotechnology: The Next Generation of Genetic Engineering
by Muhammad Sarwar Khan Iqrar Ahmad Khan Debmalya BarhApplied Molecular Biotechnology: The Next Generation of Genetic Engineering explains state-of-the-art advances in the rapidly developing area of molecular biotechnology, the technology of the new millennium. Comprised of chapters authored by leading experts in their respective fields, this authoritative reference text:Highlights the latest omics-ba
Applied Multidimensional Systems Theory
by Nirmal K. BoseRevised and updated, this concise new edition of the pioneering book on multidimensional signal processing is ideal for a new generation of students. Multidimensional systems or m-D systems are the necessary mathematical background for modern digital image processing with applications in biomedicine, X-ray technology and satellite communications. Serving as a firm basis for graduate engineering students and researchers seeking applications in mathematical theories, this edition eschews detailed mathematical theory not useful to students. Presentation of the theory has been revised to make it more readable for students, and introduce some new topics that are emerging as multidimensional DSP topics in the interdisciplinary fields of image processing. New topics include Groebner bases, wavelets, and filter banks.
Applied Multiple Regression/Correlation Analysis for the Behavioral Sciences Third Edition
by Jacob Cohen Patricia Cohen Stephen G. West Leona S. AikenA textbooks for behavioral scientists in statistics.
Applied Multivariate Statistics with R (Statistics for Biology and Health)
by Daniel ZeltermanNow in its second edition, this book brings multivariate statistics to graduate-level practitioners, making these analytical methods accessible without lengthy mathematical derivations. Using the open source shareware program R, Dr. Zelterman demonstrates the process and outcomes for a wide array of multivariate statistical applications. Chapters cover graphical displays; linear algebra; univariate, bivariate and multivariate normal distributions; factor methods; linear regression; discrimination and classification; clustering; time series models; and additional methods. He uses practical examples from diverse disciplines, to welcome readers from a variety of academic specialties. Each chapter includes exercises, real data sets, and R implementations. The book avoids theoretical derivations beyond those needed to fully appreciate the methods. Prior experience with R is not necessary.New to this edition are chapters devoted to longitudinal studies and the clustering of large data. It is an excellent resource for students of multivariate statistics, as well as practitioners in the health and life sciences who are looking to integrate statistics into their work.
Applied Muscle Biology and Meat Science
by Richard J. McCormick Min DuKnowledge of muscle biology is continuing to expand in the animal and food sciences industry, especially the understanding of the mechanisms that control skeletal muscle development, growth, and their impacts on meat production and quality. Applied Muscle Biology and Meat Science provides agriculturalists with state-of-the-art information and a platform to further explore this specialized topic. It also gives novices a comprehensive knowledge base in applied muscle biology and meat science. Many existing problems in meat science and production are due to a lack of understanding of the underlying biological mechanisms of the livestock. Careful to avoid gory processing details, the text focuses on biological changes and the appropriate manage
Applied Mycology: Entrepreneurship with Fungi (Fungal Biology)
by Amritesh Chandra ShuklaFungi are an important link in the food webs of all ecosystems. They have immense potential and comprise a myriad of useful bioactive compounds. Fungi feature in a wide range of diverse processes and applications in modern agriculture, the food science industry, and the pharmaceutical industry. In the food and drink arena, the role of fungi is historically important in the form of mushrooms and in fermented foods as yeasts for baking and brewing. These roles are supplemented by the use of fungal food processing enzymes and additives, and more recently in the development of protein-based foodstuffs from fungi. Additionally, they are used in the formulation of biofertilizers and biopesticides used as biostimulants and bioprotectants of crops. The practical use of newer techniques such as genetic recombination and robotics have revolutionized the modem agricultural biotechnology industry, and have created an enormous range of possible further applications of fungal products.Myco-materials created from mycelia (the root-like parts of fungi) are gaining attention as a sustainable alternative for a wide range of materials. They are being used as insulation, sustainable packaging, foam inserts, and even "eco-leather.” In fact, mycelium bricks are pound-for-pound stronger than concrete. In addition, medicinal uses of fungal species have been historically recorded as important agents in the pharmaceutical sciences. The potential for myco-materials seems limitless. The field of mycology and its application has become an increasingly important component in the education of industrial biotechnology. This book on applied mycology provides information helpful for developing entrepreneurial opportunities with fungi. This volume explains both the basic science and the applications of mycology and bio-resource technology with special emphasis on entrepreneurial applications. It offers a complete, one-stop resource for those interested in microbiology, food and agricultural science, medical mycology, and for those in industrial biotechnology.
Applied Myrmecology: A World Perspective (Westview Studies In Insect Biology)
by Robert K Vander MeerAnts have always fascinated the nature observer. Reports from ancient Egypt and Mesopotamia indicate that ants interested humans long ago. Myrmecology as a science had its beginning in the last century with great naturalists like Andre, Darwin, Emery, Escherich, Fabre, Fields, Forel, Janet, Karawaiew, McCook, Mayr, Smith, Wasmann and Wheeler. They studied ants as an interesting biological phenomenon, with little thought of the possible beneficial or detrimental effects ants could have on human activities (see Wheeler 1910 as an example). When Europeans began colonizing the New World, serious ant problems occurred. The first reports of pest ants came from Spanish and Portuguese officials of the fifteenth and sixteenth centuries in Trinidad, The West Indies, Central America and South America. Leaf-cutting ants were blamed for making agricultural development almost impossible in many areas. These ants, Atta and Acromyrmex species, are undoubtedly the first ants identified as pests and may be considered to have initiated interest and research in applied myrmecology (Mariconi 1970).
Applied Neurogenomics (Neuromethods #97)
by Kewal K. JainThis detailed volume reflects the considerable new developments that have taken place in the area of applied neurogenomics, particularly with the rapid progress in next generation sequencing. Beginning with an introduction to the technologies relevant to neurogenomics with an emphasis on next generation sequencing, the book also covers detailed methods relevant to the genomics of neurodegenerative diseases, particularly Alzheimer's disease and Huntington's disease, targeted sequencing of psychiatric disorders, as well as the role of genomics in the development of personalized neurology. Written in the popular Neuromethods series format, chapters provide the kind of practical description and implementation advice necessary to consistently produce successful results in the lab. Timely and convenient, Applied Neurogenomics serves as an invaluable reference for researchers working in this expanding, dynamic field.
Applied Neuropsychology of Attention: Theory, Diagnosis and Rehabilitation
by Michel Leclercq Peter ZimmermannThe concept of attention in academic psychology has been treated with varying degrees of importance over the years. From playing a key role in the 19th century, it was discarded in the first half of the 20th century, as clinical psychologists claimed it was superfluous to the essential subconscious processes of the mind, and experimental psychologists thought it was not a scientific term. Applied Neuropsychology of Attention aims to review the considerable developments in the field of attention over the last 20 years as it makes its comeback.This collection of essays forms a comprehensive overview of this crucial component of human cognitive function. The book begins with an explanation of the essential theoretical concepts and definitions. Aspects of diagnosis are then discussed as the assessment and impairments of attention are reviewed in normal ageing and in specific neurological categories. Victims of brain injury and patients with cerebrovascular or neurodegenerative diseases are considered. A critical analysis of existing practices in cognitive rehabilitation is given and a review of the techniques and methodologies used for treating attentional disturbances brings the book to a conclusion.Leclercq and Zimmermann have compiled a book of cutting-edge research which provides an effective framework to detect, analyse and understand the nature of attention deficit. The book will be invaluable to clinicians, mental health specialists and all academic psychologists in the field.
Applied NMR Spectroscopy for Chemists and Life Scientists
by Oliver Zerbe Simon JurtFrom complex structure elucidation to biomolecular interactions - this applicationoriented textbook covers both theory and practice of modern NMR applications.Part one sets the stage with a general description of NMR introducing important parameters such as the chemical shift and scalar or dipolar couplings. Part two describes the theory behind NMR, providing a profound understanding of the involved spin physics, deliberately kept shorter than in other NMR textbooks, and without a rigorous mathematical treatment of all the physico-chemical computations. Part three discusses technical and practical aspects of how to use NMR. Important phenomena such as relaxation, exchange, or the nuclear Overhauser effects and the methods of modern NMR spectroscopy including multidimensional experiments, solid state NMR, and the measurement of molecular interactions are the subject of part four. The final part explains the use of NMR for the structure determination of selected classes of complex biomolecules, from steroids to peptides or proteins, nucleic acids, and carbohydrates.For chemists as well as users of NMR technology in the biological sciences.
Applied Non-Linear Dynamical Systems (Springer Proceedings in Mathematics & Statistics #93)
by Jan AwrejcewiczThe book is a collection of contributions devoted to analytical, numerical and experimental techniques of dynamical systems, presented at the International Conference on Dynamical Systems: Theory and Applications, held in Å ódź, Poland on December 2-5, 2013. The studies give deep insight into both the theory and applications of non-linear dynamical systems, emphasizing directions for future research. Topics covered include: constrained motion of mechanical systems and tracking control; diversities in the inverse dynamics; singularly perturbed ODEs with periodic coefficients; asymptotic solutions to the problem of vortex structure around a cylinder; investigation of the regular and chaotic dynamics; rare phenomena and chaos in power converters; non-holonomic constraints in wheeled robots; exotic bifurcations in non-smooth systems; micro-chaos; energy exchange of coupled oscillators; HIV dynamics; homogenous transformations with applications to off-shore slender structures; novel approaches to a qualitative study of a dissipative system; chaos of postural sway in humans; oscillators with fractional derivatives; controlling chaos via bifurcation diagrams; theories relating to optical choppers with rotating wheels; dynamics in expert systems; shooting methods for non-standard boundary value problems; automatic sleep scoring governed by delay differential equations; isochronous oscillations; the aerodynamics pendulum and its limit cycles; constrained N-body problems; nano-fractal oscillators and dynamically-coupled dry friction.
Applied Nonautonomous and Random Dynamical Systems: Applied Dynamical Systems (SpringerBriefs in Mathematics)
by Tomás Caraballo Xiaoying HanThis book offers an introduction to the theory of non-autonomous and stochastic dynamical systems, with a focus on the importance of the theory in the Applied Sciences. It starts by discussing the basic concepts from the theory of autonomous dynamical systems, which are easier to understand and can be used as the motivation for the non-autonomous and stochastic situations. The book subsequently establishes a framework for non-autonomous dynamical systems, and in particular describes the various approaches currently available for analysing the long-term behaviour of non-autonomous problems. Here, the major focus is on the novel theory of pullback attractors, which is still under development. In turn, the third part represents the main body of the book, introducing the theory of random dynamical systems and random attractors and revealing how it may be a suitable candidate for handling realistic models with stochasticity. A discussion of future research directions serves to round out the coverage.
Applied Numerical Methods for Partial Differential Equations (Texts in Applied Mathematics #78)
by Carl L. GardnerThe aim of this book is to quickly elevate students to a proficiency level where they can solve linear and nonlinear partial differential equations using state-of-the-art numerical methods. It covers numerous topics typically absent in introductory texts on ODEs and PDEs, including: Computing solutions to chaotic dynamical systems with TRBDF2 Simulating the nonlinear diffusion equation with TRBDF2 Applying Newton’s method and GMRES to the nonlinear Laplace equation Analyzing gas dynamics with WENO3 (1D Riemann problems and 2D supersonic jets) Modeling the drift-diffusion equations with TRBDF2 and PCG Solving the classical hydrodynamic model (electro-gas dynamics) with WENO3 and TRBDF2 The book features 34 original MATLAB programs illustrating each numerical method and includes 93 problems that confirm results discussed in the text and explore new directions. Additionally, it suggests eight semester-long projects. This comprehensive text can serve as the basis for a one-semester graduate course on the numerical solution of partial differential equations, or, with some advanced material omitted, for a one-semester junior/senior or graduate course on the numerical solution of ordinary and partial differential equations. The topics and programs will be of interest to applied mathematicians, engineers, physicists, biologists, chemists, and more.
Applied Numerical Methods with MATLAB for Engineers and Scientists
by Steven C. ChapraApplied Numerical Methods with MATLAB is written for students who want to learn and apply numerical methods in order to solve problems in engineering and science. As such, the methods are motivated by problems rather than by mathematics. That said, sufficient theory is provided so that students come away with insight into the techniques and their shortcomings. McGraw-Hill's Connect, is also available as an optional, add on item. Connect is the only integrated learning system that empowers students by continuously adapting to deliver precisely what they need, when they need it, how they need it, so that class time is more effective. Connect allows the professor to assign homework, quizzes, and tests easily and automatically grades and records the scores of the student's work. Problems are randomized to prevent sharing of answers an may also have a "multi-step solution" which helps move the students' learning along if they experience difficulty.
Applied Optics and Optical Design, Part One
by A. E. Conrady"For the optical engineer it is an indispensable work." -- Journal, Optical Society of America"As a practical guide this book has no rival." -- Transactions, Optical Society"A noteworthy contribution," -- Nature (London)Part I covers allordinary ray-tracing methods, together with the complete theory of primary aberrations and as much of higher aberration as is needed for the design of telescopes, low-power microscopes and simple optical systems. Chapters: Fundamental Equations, Spherical Aberration, Physical Aspect of Optical Images, Chromatic Aberration, Design of Achromatic Object-Glasses, The Optical Sine Theorem, Trigonometric Tracing of Oblique Pencils, General Theory of Perfect Optical Systems, and Ordinary Eyepieces.Part II extends the coverage to the systematic study and design of practically all types of optical systems, with special attention to high-power microscope objectives and anastigmatic photographic objectives. Edited and completed from the author s manuscript by Rudolf Kingslake, Director of Optical Design, Eastman Kodak Company. Chapters: Additional Solutions by the Thin-Lens Method , Optical Path Differences, Optical Path Differences at an Axiallmage Point, Optical Tolerances, Chromatic Aberration as an Optical Path Difference, The Matching Principle and the Design of Microscope Objectives, Primary Aberrations of Oblique Pencils, Analytical Solutions for Simple Systems with Remote Stop, Symmetrical Photographic Objectives, and Unsymmetrical Photographic Objectives.
Applied Optics and Optical Design, Part Two (Dover Books on Physics)
by A. E. Conrady"For the optical engineer it is an indispensable work." -- Journal, Optical Society of America"As a practical guide this book has no rival." -- Transactions, Optical Society"A noteworthy contribution," -- Nature (London)This two-volume paperback republication of A. E. Conrady's classic work presents his complete system of optical design. The only work of its kind in English, this set leads the reader step by step from the fundamental concepts of geometrical and physical optics up to the point where he can design the simpler optical systems without aid. It remains the only detailed work on the subject written with the needs of the practical designer and the self-taught constantly in mind. For most of the text, no mathematics above trigonometry is needed; occasional sections require some calculus and analytical geometry.Part I covers all ordinary ray-tracing methods, together with the complete theory of primary aberrations and as much of higher aberration as is needed for the design of telescopes, low-power microscopes and simple optical systems. Chapters: Fundamental Equations, Spherical Aberration, Physical Aspect of Optical Images, Chromatic Aberration, Design of Achromatic Object-Glasses, Extra-Axial Image Points, The Optical Sine Theorem, Trigonometric Tracing of Oblique Pencils, General Theory of Perfect Optical Systems, and Ordinary Eyepieces.Part II extends the coverage to the systematic study and design of practically all types of optical systems, with special attention to high-power microscope objectives and anastigmatic photographic objectives. Edited and completed from the author's manuscript by Rudolf Kingslake, Director of Optical Design, Eastman Kodak Company. Chapters: Additional Solutions by the Thin-Lens Method, Optical Path Differences, Optical Path Differences at an Axial Image Point, Optical Tolerances, Chromatic Aberration as an Optical Path Difference, The Matching Principle and the Design of Microscope Objectives, Primary Aberrations of Oblique Pencils, Analytical Solutions for Simple Systems with Remote Stop, Symmetrical Photographic Objectives, and Unsymmetrical Photographic Objectives.
Applied Optics Fundamentals and Device Applications: Nano, MOEMS, and Biotechnology
by Mark A. MentzerHow does the field of optical engineering impact biotechnology? Perhaps for the first time, Applied Optics Fundamentals and Device Applications: Nano, MOEMS, and Biotechnology answers that question directly by integrating coverage of the many disciplines and applications involved in optical engineering, and then examining their applications in nanobiotechnology. Written by a senior U.S. Army research scientist and pioneer in the field of optical engineering, this book addresses the exponential growth in materials, applications, and cross-functional relevance of the many convergent disciplines making optical engineering possible, including nanotechnology, MEMS, (MOEMS), and biotechnology. Integrates Coverage of MOEMS, Optics, and Nanobiotechnology—and Their Market Applications Providing an unprecedented interdisciplinary perspective of optics technology, this book describes everything from core principles and fundamental relationships, to emerging technologies and practical application of devices and systems—including fiber-optic sensors, integrated and electro-optics, and specialized military applications. The author places special emphasis on: Fiber sensor systems Electro-optics and acousto-optics Optical computing and signal processing Optical device performance Thin film magnetic memory MEMS, MOEMS, nano- and bionanotechnologies Optical diagnostics and imaging Integrated optics Design constraints for materials, manufacturing, and application space Bridging the technology gaps between interrelated fields, this reference is a powerful tool for students, engineers and scientists in the electrical, chemical, mechanical, biological, aerospace, materials, and optics fields. Its value also extends to applied physicists and professionals interested in the relationships between emerging technologies and cross-disciplinary opportunities. Author Mark A. Mentzer is a pioneer in the field of optical engineering. He is a senior research scientist at the U.S. Army Research Laboratory in Maryland. Much of his current work involves extending the fields of optical engineering and solid state physics into the realm of biochemistry and molecular biology, as well as structured research in biophotonics.
Applied Organic Chemistry: Reaction Mechanisms and Experimental Procedures in Medicinal Chemistry
by Surya K. DeAn indispensable guide for all synthetic chemists who want to learn about the most relevant reactions and reagents employed to synthesize important heterocycles and drugs! The synthesis of natural products, bioactive compounds, pharmaceuticals, and drugs is of fundamental interest in modern organic chemistry. New reagents and reaction methods towards these molecules are being constantly developed. By understanding the mechanisms involved and scope and limitations of each reaction applied, organic chemists can further improve existing reaction protocols and develop novel efficient synthetic routes towards frequently used drugs, such as Aspirin or Penicillin. Applied Organic Chemistry provides a summary of important (name) reactions and reagents applied in modern organic chemistry and drug synthesis. It covers rearrangement, condensation, olefination, metathesis, aromatic electrophilic substitutions, Pd-catalyzed C-C bond forming reactions, multi-component reactions, as well as oxidations and reductions. Each chapter is clearly structured, providing valuable information on reaction details, step-by-step mechanism, experimental procedures, applications, and (patent) references. By providing mechanistic information and representative experimental procedures, this book is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry. Hot Topic: Reviews important classes of organic reactions (incl. name reactions) and reagents in medicinal chemistry. Useful: Provides information on reaction details, common reagents, and functional group transformations used to synthesize natural products, bioactive compounds, drugs, and pharmaceuticals, e.g. Aspirin, Penicillin. Unique: For every reaction the mechanism is explained step by step, and representative experimental procedures are given, unlike most books in this area. User-friendly: Chapters are clearly structured making it easy for the reader to compare different reactions. Applied Organic Chemistry is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry.