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Molecular & Cell Biology For Dummies
by Rene Fester KratzYour insider guide to the stuff of life 3.8 billion years old and counting, there’s more than a little to know about the fundamentals of how life works. This friendly guide takes you from the primordial soup to the present, explaining how specialized cells have given rise to everything living, from the humblest amoeba to walking, talking human beings. Whether you’re enrolled in a cell or molecular biology course and need a straightforward overview, or are just curious about the latest advances, this fully updated edition is your all-access ticket to our inner world. Molecular & Cell Biology For Dummies decodes jargon and theories that can tax even the most devoted student. It covers everything from basic principles to how new technology, genetic testing, and microarray techniques are opening up new possibilities for research and careers. It also includes invaluable tips on how to prepare for—and ace—your exams! Explore the structure and function of the cells—and find out why cellular context is crucial to the study of disease Discover how molecular biology can solve world problems Understand how DNA determines traits and is regulated by cells Enhance your knowledge and results with online resources and study tips From microscopic details to macro concepts, this book has something for you.
Molecular & Cell Biology For Dummies
by Rene Fester KratzYour insider guide to the stuff of life 3.8 billion years old and counting, there’s more than a little to know about the fundamentals of how life works. This friendly guide takes you from the primordial soup to the present, explaining how specialized cells have given rise to everything living, from the humblest amoeba to walking, talking human beings. Whether you’re enrolled in a cell or molecular biology course and need a straightforward overview, or are just curious about the latest advances, this fully updated edition is your all-access ticket to our inner world. Molecular & Cell Biology For Dummies decodes jargon and theories that can tax even the most devoted student. It covers everything from basic principles to how new technology, genetic testing, and microarray techniques are opening up new possibilities for research and careers. It also includes invaluable tips on how to prepare for—and ace—your exams! Explore the structure and function of the cells—and find out why cellular context is crucial to the study of disease Discover how molecular biology can solve world problems Understand how DNA determines traits and is regulated by cells Enhance your knowledge and results with online resources and study tips From microscopic details to macro concepts, this book has something for you.
Molecular & Cell Biology of the Liver
by Albert V. LeBoutonMolecular and Cell Biology of the Liver features the latest research findings regarding liver structure and function. A unique feature of the book is the brief science reviews that are included in each chapter which provide essential background information to allow readers to better grasp the subject matter within a chapter. The book covers liver biology from the molecular level to groups of liver cells and explains how groups of hepatocytes interact in similar microenvironments. Other important cell types found in the liver are also examined. Illustrations ranging from electron micrographs to fully rendered drawings act as visual aids to help readers understand complex structural-functional interactions. Molecular and Cell Biology of the Liver will benefit hepatologists, gastroenterologists, cell biologists, anatomists, toxicologists, and other researchers interested in liver structure and function.
Molecular & Diagnostic Imaging in Prostate Cancer: Clinical Applications And Treatment Strategies (Advances in Experimental Medicine and Biology #1096)
by Heide SchattenThe second of two companion books which address the biology and clinical aspects of prostate cancer. This volume, Prostate Cancer: Molecular & Diagnostic Imaging and Treatment Stategies, discusses both classic and the most recent imaging approaches for detection, early diagnosis and treatment of prostate cancer. The companion title, Cell & Molecular Biology of Prostate Cancer, covers classic and modern cell and molecular biology as well as genetics, epigenetics, mitochondrial dysfunctions and apoptosis, cancer stem cells, angiogenesis, progression to metastasis, and treatment strategies including clinical trials related to prostate cancer. Taken together, these volumes form one comprehensive and invaluable contribution to the literature.
Molecular Advances in Insect Resistance of Field Crops: Modern and Applied Approaches
by Amarjit S. TandaBased on the understanding that tolerance to pest pressure increases with less crop stress, this book covers all aspects of the molecular mechanisms underlying insect resistance in field crops. Detailed descriptions, accompanied by numerous photographs and schematic drawings, are available for “hot topics” such as genetically engineered crops, crispr/cas9 system, insect pest resistance technology, host plant resistance, and other major breakthroughs. Specific case studies include, but not limit to, the use of insect resistant cultivars in IPMT programs, utilization of glucosinolate-myrosinase processes in oilseed crops, and role of genetic in rice breeding technology.
Molecular Analyses (Medical Genomics and Proteomics)
by Scott O. RogersDNA and RNA extraction methods from a variety of tissues and samples are now routine, including extraction from single cells. Many methods are now automated. Sequencing efficiency has reached the point where it is now possible to obtain gigabases of data, both quickly and inexpensively. Such methods permit the identification of gene versions, including those associated with disease (e.g. small nucleotide polymorphism analyses, or SNPs). The general public as well as clinicians can now access a wide variety of literature on the molecular bases of diseases, allowing them to better assess disease risks and treatments. This volume concentrates on medically-focused methods, and therefore the major audience will be medical professionals, students, and those involved in medically-related research endeavors. There are also papers in this volume dealing specifically with methods developed to analyze large sequence data sets. Many methods reviewed herein are more broadly applicable to other fields in biology, chemistry, bioinformatics, and bioengineering, and are intended for a broad readership. Key Features Summarizes nucleic acid extractions from a wide variety of tissues and cells Describes processes of nucleic acid preservation Reviews forensic sampling, detection of nucleic acids, and delivery of nucleic acids to multicellular organisms Provides essential guidance for sequencing, sequence analysis, database searches, and phylogenetic analyses Includes additional methods useful for analysis of nucleic acids and proteins Related Titles DeSalle, et al. Phylogenomics: A Primer (ISBN 978-0-3670-2849-7). Jennings, W. B. Phylogenomic Data Acquisition: Principles and Practice (ISBN 978-0-3678-6980-9). Wang, X. Next-Generation Sequencing Data Analysis (ISBN 978-1-4822-1788-9) Sung, W.-K. Algorithms for Next-Generation Sequencing (ISBN 978-0-3676-5797-0)
Molecular Analysis and Genome Discovery
by Ralph Rapley Stuart HarbronMolecular Analysis and Genome Discovery, Second Edition is a completely revised and updated new edition of this successful book. The text provides a comprehensive overview of recent developments in the fast moving field of molecular based diagnostics of disease markers. Key concepts and applications are provided alongside practical information on current techniques currently being researched and developed. Each chapter offers an up-to-date analysis of the subject encompassing the very latest technology platforms and is an essential reference for researchers in the field looking for an up-to-date overview of the subject. The book will also be an indispensable resource for those working in the biotechnology and pharmaceutical industries. New for this edition: chapters on Genotyping through Mutation Detection; Differential Gene Expression; Haplotyping and Molecular Profiling.
Molecular Applications in Cytology
by Fernando C. SchmittThis book is intended for practicing pathologists and cytopathologists, as well as for pathology trainees and cytotechnicians. It starts with a detailed description of the extremely important pre-analytical phase for molecular testing followed by a presentation of the key tests and their application in different organs, e.g. the lung or thyroid. Step-by-step instructions for the different assays, reporting and clinical integration of the test results are discussed. The authors help the reader to benefit from their experiences by providing a valuable tool for the implementation of these techniques in daily practice.Though the use of molecular techniques is well established in surgical biopsies, to date they are not widely used in connection with cytological material. However, in some fields like lung cancer or aspirates from the pancreas and biliary tract the only available material for diagnosis is the cytological preparation a fact that has created a need for the standardization of molecular techniques on cytology.
Molecular Applications of Quantum Defect Theory
by Ch JungenAs a consequence of new experimental techniques in optical and collision physics, such as multiphoton excitation and VUV radiation generation, quantum defect theory (QDT) has become more widely used as a theoretical tool for experimentalists. Drawing together a historical body of work that contains key research and review papers, Molecular Applica
Molecular Approaches for Sustainable Insect Pest Management
by OmkarThis book offers a range of environmentally benign molecular mechanisms which are safer alternative strategies for effective insect pest management. In modern era of biotechnology, there has been much advancement in the field of molecular biology, where many more techniques have evolved which can be helpful in the field of pest management too. Plant resistance, development of transgenic plants, and many more techniques are being considered the panacea to pest problems. On the other hand, there are wide spread concerns of the safety of biotechnological interventions with nontarget organisms including humans. While the world stands divided on the ethical issues of these approaches and the many safety concerns, scientists believe that well thought of biotechnological interventions are probably the only safest ways possible for reducing pest attacks on crops. It explores various techniques and aspects related to molecular pathways for crop pest control. This book is a useful resource for postgraduate students and researchers of agriculture sciences, plant pathology and plant physiology. It is also useful for policy planners in agriculture.
Molecular Approaches for the Detection of Fungal Phytopathogens
by Deepa Nagaraju Sreenivasa Marikunte Yanjarappa Charith Raj Adkar PurushothamaThis book discusses recent advancements and updates in the molecular diagnostics of fungal phytopathogens. The techniques covered in the seventeen chapters help in understanding the importance of early detection of fungal pathogens and their toxins in both post- and pre-harvest stages of crop production. Molecular Approaches for the Detection of Fungal Phytopathogens describes the fungal identification and isolation from different sources such as food, feed and cereals using molecular approaches. These include variants of polymerase chain reaction (PCR) involving: generic (genus and species) and gene-specific primers, RNA-sequence-based next-generation sequences, microarrays, serial analysis of gene expression, fluorescence in-situ hybridization, loop-mediated isothermal amplification, macroarrays, PCR-denaturing gradient gel electrophoresis, magnetic capture hybridization-PCR, nanotechnology, and immunoassays providing faster and more sensitive approaches than traditional methods that overcome challenges by developing novel disease control strategies.Features Explores various diagnostic strategies for phytopathogens Discusses early detection methods when fungal spores are low or there are no visible symptoms Provides a historical perspective and compares the traditional methods of detection with the current molecular techniques Describes details of the protocol of every technique mentioned Covers point-of-care testing for fungal pathogens and quality assurance for molecular testing in plant health
Molecular Approaches in Natural Resource Conservation and Management
by J. Andrew Dewoody John W. Bickham Charles H. Michler Krista M. Nichols Olin E. Rhodes Keith E. Woeste Jr.Recent advances in molecular genetics and genomics have been embraced by many in natural resource conservation. Today, several major conservation and management journals are now using "genetics" editors to deal solely with the influx of manuscripts that employ molecular data. The editors have attempted to synthesize some of the major uses of molecular markers in natural resource management in a book targeted not only at scientists but also at individuals actively making conservation and management decisions. To that end, the text features contributors who are major figures in molecular ecology and evolution - many having published books of their own. The aim is to direct and distill the thoughts of these outstanding scientists by compiling compelling case histories in molecular ecology as they apply to natural resource management.
Molecular Approaches in Plant Biology and Environmental Challenges (Energy, Environment, and Sustainability)
by Sunil Kumar Sudhir P. Singh Santosh Kumar Upadhyay Ashutosh PandeyThis book discusses molecular approaches in plant as response to environmental factors, such as variations in temperature, water availability, salinity, and metal stress. The book also covers the impact of increasing global population, urbanization, and industrialization on these molecular behaviors. It covers the natural tolerance mechanism which plants adopt to cope with adverse environments, as well as the novel molecular strategies for engineering the plants in human interest. This book will be of interest to researchers working on the impact of the changing environment on plant ecology, issues of crop yield, and nutrient quantity and quality in agricultural crops. The book will be of interest to researchers as well as policy makers in the environmental and agricultural domains.
Molecular Approaches to Soil, Rhizosphere and Plant Microorganism Analysis
by John E. Cooper J. R. RaoMicrobial ecologists from Europe, the US, and New Zealand critique many of the molecular techniques that are currently used to study soil and plant micro-organisms at the community, population, taxonomic, and functional group levels. They do not provide a bench manual, but do provide technical information on polymerase chain reaction sequences and experimental protocols. Among their topics are meta-genomics for studying soil microbial communities, and transcriptomics for determining gene expression in symbiotic root-fungus interactions.
Molecular Architectonics and Nanoarchitectonics (Nanostructure Science and Technology)
by Katsuhiko Ariga Thimmaiah GovindarajuThis book is the ultimate assembly of recent research activities on molecular architectonics and nanoarchitectonics by authors who are worldwide experts. The book proposes new ways of creating functional materials at the nano level using the concepts of molecular architectonics and nanoarchitectonics, which are expected to be the next-generation approaches beyond conventional nanotechnology. All the contents are categorized by types of materials, organic materials, biomaterials, and nanomaterials. For that reason, non-specialists including graduate and undergraduate students can start reading the book from any points they would like. Cutting-edge trends in nanotechnology and material sciences are easily visible in the contents of the book, which is highly useful for both students and experimental materials scientists.
Molecular Aspects of Aging: Understanding Lung Aging
by Mauricio Rojas Silke Meiners Claude Jourdan Le SauxMolecular Aspects of Aging: Understanding Lung Aging covers recent research in the mechanisms that contribute to cellular senescence. Covering universal themes in aging, such as the exhaustion of stem cells and subsequent loss of the regenerative refueling of organs as well as immunosenescence, this text illuminates new directions for research not yet explored in the still poorly investigated area of molecular mechanisms of lung aging. The molecular nature of general aging processes is explored with targeted coverage on how to analyze lung aging through experimental approaches.
Molecular Aspects of Hematologic Malignancies
by Malgorzata Dawidowska Tomasz Szczepanski Michal WittThis book provides a state-of-the-art approach to the molecular basis of hematologic diseases and its translation into improved diagnostics and novel therapeutic strategies. Several representative hemato-oncologic malignancies are analyzed in detail: acute lymphoblastic leukemia, acute myeloid leukemia, B-cell Non-Hodgkin lymphomas, multiple myeloma, chronic lymphocytic leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. Experts in the field describe the molecular methods applied for modern diagnostics and therapies, such as hematopoietic stem cell transplantation, donor recipient matching, banking of biological material, analyses of post-transplant chimerism, and minimal residual disease monitoring. The volume concludes with an extensive section comprising thorough step-by-step protocols of molecular techniques in hematology, all of them validated in the authors' own laboratories.
Molecular Aspects of Iron Metabolism in Pathogenic and Symbiotic Plant-Microbe Associations
by Dominique Expert Mark R. O'BrianIron plays a key role in biology as essential cofactor of numerous proteins. However, since it is only slightly soluble its bioavailability can be readily compromised under aerobic conditions. Moreover, due to its ability to catalyze the generation of free radicals, iron can also be toxic. Thus, it doesn't surprise that living organisms have developed sophisticated means for acquiring iron whilst tightly controlling the intracellular concentrations of this metal in response to environmental conditions. Also, the critical role of iron has long been acknowledged in host vertebrate-parasite relationships where both partners compete for the acquisition of this essential element and activate complex signaling cascades to control their iron homeostasis during infection. Following the great interest that the mechanisms regulating the acquisition of iron and the control of iron homeostasis have generated among researchers studying plant-pathogen and legume-rhizobia interactions, this book offers a comprehensive analysis of irons' various roles in the plant-microbial associations. The introductory chapter stresses the essentiality of iron in biological systems. The second chapter surveys the abundance of information on iron's pivotal role in microbial plant pathogenesis and defence. Finally, the third chapter reviews the advances in our understanding of iron metabolism in the rhizobia, soil bacteria able to establish a symbiotic association with legumes and carry out nitrogen fixation. Molecular Aspects of Iron Metabolism in Pathogenic and Symbiotic Plant-Microbe Associations is a valuable resource to microbiologists, pathologists and scientists interested in iron uptake and metabolism in microbial pathogenesis, rhizobia legume associations, and plant physiology and immunity.
Molecular Aspects of Plant-Pathogen Interaction
by Archana Singh Indrakant K. SinghThe book offers an integrated overview of plant–pathogen interactions. It discusses all the steps in the pathway, from the microbe–host-cell interface and the plant’s recognition of the microbe to the plant’s defense response and biochemical alterations to achieve tolerance / resistance. It also sheds light on the classes of pathogens (bacteria, fungus and viruses); effector molecules, such as PAMPs; receptor molecules like PRRs and NBS-LRR proteins; signaling components like MAPKs; regulatory molecules, such as phytohormones and miRNA; transcription factors, such as WRKY; defense-related proteins such as PR-proteins; and defensive metabolites like secondary metabolites. In addition, it examines the role of post-genomics, high-throughput technology (transcriptomics and proteomics) in studying pathogen outbreaks causing crop losses in a number of plants. Providing a comprehensive picture of plant-pathogen interaction, the updated information included in this book is valuable for all those involved in crop improvement.
Molecular Astrophysics
by A. G. TielensFocusing on the organic inventory of regions of star and planet formation in the interstellar medium of galaxies, this comprehensive overview of the molecular universe is an invaluable reference source for advanced undergraduates through to entry-level researchers. It includes an extensive discussion of microscopic physical and chemical processes in the universe; these play a role in the excitation, spectral characteristics, formation, and evolution of molecules in the gas phase and on grain surfaces. In addition, the latest developments in this area of molecular astrophysics provide a firm foundation for an in-depth understanding of the molecular phases of the interstellar medium. The physical and chemical properties of gaseous molecules, mixed molecular ices, and large polycyclic aromatic hydrocarbon molecules and fullerenes and their role in the interstellar medium are highlighted. For those with an interest in the molecular universe, this advanced textbook bridges the gap between molecular physics, astronomy, and physical chemistry.
Molecular Bases of Anesthesia (Handbooks in Pharmacology and Toxicology)
by Eric Moody and Phil SkolnickMolecular Bases of Anesthesia provides a clear overview of the state of knowledge about anesthetic mechanisms at the molecular level of occurrence and focusing on the latest state-of-the-art techniques that relate to how anesthetic drugs cause unconsciousness. With contributions by leading experts, this timely book includes chapters on how
Molecular Basics of Liquids and Liquid-Based Materials (Physical Chemistry in Action)
by Katsura Nishiyama Tsuyoshi Yamaguchi Toshiyuki Takamuku Norio YoshidaThis book sheds light on the molecular aspects of liquids and liquid-based materials such as organic or inorganic liquids, ionic liquids, proteins, biomaterials, and soft materials including gels. The reader discovers how the molecular basics of such systems are connected with their properties, dynamics, and functions. Once the use and application of liquids and liquid-based materials are understood, the book becomes a source of the latest, detailed knowledge of their structures, dynamics, and functions emerging from molecularity. The systems discussed in the book have structural dimensions varying from nanometers to millimeters, thus the precise estimation of structures and dynamics from experimental, theoretical, and simulation methods is of crucial importance. Outlines of the practical knowledge needed in research and development are helpfully included in the book.
Molecular Basis and Emerging Strategies for Anti-aging Interventions
by Syed Ibrahim Rizvi Ufuk ÇakatayThis book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging interventions, while also discussing the discovery of targets for geroprotective drugs. Although significant medical advances in the treatment and eradication of life-threatening conditions such as cardiovascular and infectious disease have been made over the past five decades, the prevalence of age-related disorders still remains high in older populations. Intervening into aging is the next frontier in contemporary medicine, and will be of increasing importance over time, as other sources of poor health are combated more and more successfully. Given the universal interest in anti-aging strategies, the book will appeal to a very broad audience. It addresses a diverse range of anti-aging interventions – including stem cells, autophagy, senolytics, anti-inflammatory methods, and telomerase induction – that will be of interest to scientists and researchers from various disciplines in the life sciences.
Molecular Basis of Aging (CRC Press Revivals)
by Alvaro Macieira-CoelhoUsing a new, integrative approach, Molecular Basis of Aging describes the aging phenomenon within mammalian organisms from the perspective of changes in information storage and coordination between hierarchical orders of structure. This unique approach provides the reader with a thorough insight into the evolution of molecular, cellular, tissue, and organ systems and processes in mammals. This informative volume contains up-to-date reviews of:
Molecular Basis of Developmental and Stem Cell Regulation: Classical Models Revised (Results and Problems in Cell Differentiation #72)
by Hisato KondohThis book provides a comprehensive overview of the molecular basis of developmental and stem cell regulation. It revisits some of the classical models of developmental biology and puts them in context with the findings of modern stem cell research and developmental biology. Biomedical research is embarking on a new era due to new tools, which are exemplified by stem cell technologies, single-cell transcriptome analysis, and live imaging at a single-cell resolution. Publications based on cutting-edge technologies do often not provide the readers with deep biological backgrounds. This causes the risk that precious data are reduced to highly specific descriptions without sufficient biological contexts.Contemporary developmental biology on the other hand as written in many textbooks, is to a significant extent based on conceptions backdated many decades ago, and is not necessarily supported by recent findings. Yet, the prevailing classical notions tend to mislead modern biomedical researches.This book not only presents current models for developmental processes but also reinterprets and re-evaluates classic observations, thus linking classical and modern worlds of developmental biology. Spanning from molecular mechanisms to highly embryological matters it provides a bridge between these different disciplines.Written for advanced students of developmental and stem cell biology, researchers and teaching scholars, this book provides a new road map to modern developmental biology and stem cell biology.