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The Mekong Delta System
by Claudia Kuenzer Fabrice G. RenaudThis book about the Mekong Delta presents a unique collection of state-of-the-art contributions by international experts from different scientific disciplines about the characteristics and pressing water-related challenges of the Mekong Delta in Vietnam. The Mekong Delta belongs to one of the areas, which are to expect the largest challenges concerning environmental change and climate change induced sea level rise . The Delta acts as the "rice bowl" of Southeast Asia and is home to over 17 Million people, who need to cope with ecologic as well as socio-economic changes linked to the rapid economic development of the country. Annual floods, severe droughts, salt water intrusion, degrading water quality, tropical cyclones, hydrologic changes due to hydropower projects in the upstream of the Mekong, coastal erosion, and the loss of biodiversity are some of the problems in the region. Heterogeneous resource management responsibilities, and the fact that the Mekong - and thus also the Delta - is influenced by six countries aggravate the situation. Integrated water resources management and fostered cooperation and information exchange are pressing needs for the sustainable development of the Delta.
Melanin Chemistry Explored by Quantum Mechanics: Investigations for Mechanism Identification and Reaction Design
by Ryo Kishida Susan Meñez Aspera Hideaki KasaiThis book discusses recent advances in theoretical–computational studies on the biosynthesis of melanin pigment (melanogenesis). These advances are being driven by the development of high-performance computers, new experimental findings, and extensive work on medical applications involving the control of pigmentation and the treatment of challenging dermatological diseases. Understanding the elementary processes involved in chemical reactions at the atomic scale is important in biochemical reaction design for effective control of the pigmentary system. Accordingly, the book focuses on the elementary steps involved in melanogenesis, which crucially affect the composition of the resulting melanin pigment by means of competitive reactions. The book also addresses reactions analogous to melanogenesis, with a focus on o-quinone reactions, which are especially important for understanding melanogenesis-associated cytotoxicity.
Melanin-Concentrating Hormone and Sleep: Molecular, Functional And Clinical Aspects
by S. R. Pandi-Perumal Pablo Torterolo Jaime M. MontiThis book offers a compilation of papers on the role of melanin-concentrating hormone (MCH) in sleep, sleep disorders and neuroendocrine functions. Leading experts in sleep medicine, psychiatry and neuroendocrinology provide a broad perspective on the field, from the anatomical structure and physiology of the MCH system to the connection with other systems influencing sleep and diseases like anxiety and depression. The potential of MCHR-1 antagonists as anxiolytic/antidepressant drugs is also reviewed. The book will represent an interdisciplinary guide for sleep disorder specialists, sleep researchers, psychiatrists, neurologists, psychologists, and behavioral sleep medicine specialists.
Melanins and Melanosomes: Biosynthesis, Structure, Physiological and Pathological Functions
by Patrick A. Riley Jan BorovanskyThe surface pigmentation of vertebrates is controlled by specialized cells able to synthesize a variety of pigments collectively known as melanins. Recent research has shown that melanins are produced not only in the skin but also in many other sites such as the eye, inner ear, muscles, etc., - where they are engaged in some unanticipated roles. The details of the synthetic pathway, the complexities of its regulation and biological significance that have been unravelled in recent research comprise a fascinating story and are of key importance in understanding the nature of diseases, including malignant melanoma one of the most rapidly spreading cancers.
Melanins: Functions, Biotechnological Production, and Applications
by Guillermo GossetThis book provides an up-to-date overview of the biological functions of melanins, their biotechnological production, and their industrial applications. The melanins form a group of polymeric pigments found in most organisms. These natural products are generated by the oxidation of phenolic and indolic molecules yielding melanins, which include eumelanin, pheomelanin, pyomelanin, and the allomelanins. These pigments have diverse biological functions, including photoprotection, thermoregulation, antioxidation, virulence, and metal ion sequestration. Melanins have physicochemical properties that have proven useful in the optical, electronic, material, agriculture, cosmetic, pharmaceutical, and medical industries. The chapters in this book provide an in-depth analysis of the current issues and challenges in this field. Topics covered include the properties, biogenesis, and evolution of melanosomes. The book also addresses the synthesis and industrial production of melanins by microorganisms. The metabolic pathways for the synthesis of several types of polymeric pigments in microorganisms and their role in pathogenesis are reviewed. The large-scale production and purification of melanins to provide this product for industrial applications is a formidable challenge. Two chapters present and discuss the state-of-the-art used for the generation of microbial melanin-production strains and the processes for the biotechnological synthesis and purification of these pigments. Melanins are polymers that can interact with metals, a chapter reviews this capacity in the context of technological applications, including electrochemical energy storage and metal recovery. These polymers are materials having favorable characteristics for photonic applications, including UV blocking and broadband absorption. The current advances in the application of these pigments in optically active materials are presented and discussed.
The Melanotropic Peptides: Volume III: Mechanisms of Action and Biomedical Applications
by M.E. HadleyThe three volumes on "The Melanotropic Peptides" are the outcome of a conference of the same name that was held in Tucson, Arizona, from October 11-12, 1986. Volume III discusses the known mechanisms of action of the two melanotropic peptides, and concludes with a discussion of the possible biomedical applications of the melanotropins.
The Melanotropic Peptides: Volume I: Source, Synthesis, Chemistry, Secretion, Circulation and Metabolism
by M.E. HadleyThe three volumes on "The Melanotropic Peptides" are the outcome of a conference of the same name that was held in Tucson, Arizona, from October 11-12, 1986. The format of the three volumes provides a complete coverage of what is known about the Melanotropic Peptides. Volume I provides information on the source, synthesis, chemistry, mechanism of secretion, control of secretion, and the circulation and metabolism of the melanotropic peptides.
The Melanotropic Peptides: Volume II: Biological Roles
by M.E. HadleyThe three volumes on "The Melanotropic Peptides" are the outcome of a conference of the same name that was held in Tucson, Arizona, from October 11-12, 1986. Volume II disdcusses the diverse putative physiologial roles of MSH and MCH. A concluding chapter of this volume provides a discussion of the possible evolutionary relationships between MSH and MCH in the control of color change.
Melatonin: Methods and Protocols (Methods in Molecular Biology #2550)
by Ralf Jockers Erika CeconThis volume covers the latest techniques that study the synthesis of melatonin, its receptor function, and its effects at the cellular and systemic level. The chapters are organized into three parts. Part One describes methods for the detection of melatonin and its biological derivatives in various biological samples, the manipulation of melatonin synthesis by the pineal gland in animals, and the principal source of melatonin in mammals. Part Two explores methods to measure the biological effects and consequences of melatonin binding to high-affinity G protein-coupled receptors. Part Three describes methods to measure the physiological effects that are regulated by melatonin in animals, particularly in rodent models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and thorough, Melatonin: Methods and Protocols is a valuable resource for any researcher interested in investigating melatonin, from its production to its mechanisms of action and systemic effects.
Melatonin: Phytomelatonin in normal and challenging environments (Plant in Challenging Environments #4)
by Soumya Mukherjee Francisco J. CorpasThe new edited volume on phytomelatonin and its diverse roles in plants under a challenging environment shall be an important reference book with updated information and future perspectives on the involvement of this biomolecule in stress resilience in plants. Investigations on different aspects of melatonin in plants have undergone a prolific surge in the last decade. In view of such a considerable volume of investigations in melatonin, the proposed new volume will collate its role in different aspects of plants signaling, growth and metabolism. In this context, it has been important to understand its function as a stress priming molecule that executes associative synergistic relation with various other plant growth regulators (viz. nitric oxide, hydrogen sulfide, inorganic ions, and enzymes). Thus, crop management under diverse stressful environments can be better achieved by elucidating our current understanding of the role of melatonin and its interplay with various plant metabolites. The book shall provide a collation of recent advancements in genomic, transcriptomic, and metabolomic approaches to decipher the molecular mechanisms of melatonin signaling and its agronomic importance in plants.
Melatonin: Biosynthesis, Physiological Effects, and Clinical Applications
by Russel J. Reiter Hing-Sing YuMelatonin: Biosynthesis, Physiological Effects, and Clinical Applications provides a thorough review of recent advances in major areas of melatonin research. The book is arranged in a logical sequence, beginning with the history of melatonin and then proceeding to cover its biochemistry and secretion, physiological effects, and clinical significance. New findings and current concepts are emphasized, and a significant amount of previously unpublished data are included. The book will be an important reference for neurobiologists, cell biologists, ophthalmologists, endocrinologists, neuroendocrinologists, reproductive biologists, psychiatrists, and other researchers and clinicians interested in melatonin.
Melatonin: Therapeutic Value and Neuroprotection
by Venkatramanujan Srinivasan Gabriella Gobbi Samuel D. Shillcutt Sibel SuzenThere is growing interest in the field of melatonin research regarding its neurobiological mechanisms as well as its repercussions in clinical practice. Melatonin: Therapeutic Value and Neuroprotection explores melatonin's neuroprotective effects and discusses the therapeutic potential of melatonin and melatonin agonists in treating neurodegenerati
Melatonin in Plants: A Pleiotropic Molecule for Abiotic Stresses and Pathogen Infection
by Ravinder Kumar Muhammad Ahsan Altaf Milan Kumar Lal Rahul Kumar TiwariThis edited book highlights the multifunctional role of the ubiquitous molecule, melatonin in crop plants. The major focus of this edition is to provide a comprehensive insight into the key focus is on Melatonin mediated alleviation of abiotic stresses and pathogens infection. The inception of melatonin as an animal hormone and the subsequent discovery of its multifaceted function in the animal system has revolutionized the research on this penial hormone. During the last decade, the discovery, quantification and functional studies of melatonin as phytohormone has emerged at a rapid pace. Recently, this phyto-protectant has become an integral component of lab and field-based research on the mitigation of adverse effects of climate-driven abiotic stresses and postharvest biology and technology.The book explores melatonin mediated management of various abiotic stresses such as drought, salinity, heat and cold temperature. The book also focuses on role of melatonin in heavy metal stress, viral, bacterial, and fungal diseases, and, also contains chapter on melatonin facilitated nutrient use efficiency in plants. This book is of interest to postharvest industries, horticulturists, scientists, researchers, and students.
Melatonin in Plants: A Regulator for Plant Growth and Development
by Ravinder Kumar Muhammad Ahsan Altaf Milan Kumar Lal Rahul Kumar TiwariThis book highlights the multifunctional role of the ubiquitous molecule, melatonin, in crop plants. The major focus of this edition is to provide detailed insights into morphophysiological, biochemical, and molecular responses of melatonin in the growth and development of the plant. The inception of melatonin as an animal hormone and the subsequent discovery of its multifaceted function in the animal system has triggered the research on this pineal gland hormone. During the last decade, the discovery, quantification and functional studies of melatonin as phytohormone has emerged at a rapid pace. Recently, this phyto-protectant has become an integral component of lab and field-based research on the mitigation of adverse effects of climate-driven abiotic stresses and postharvest biology and technology.The book explores various biosynthetic pathways and detection of melatonin covering its role in flowering, fruit development, photosynthesis, respiration, hormonal crosstalk, post-harvest biology and reactive oxygen species and nitrogen cycles. This book is of high interest to postharvest industries, horticulturists, scientists, researchers, and students.
Melatonin in Plants: Role in Plant Growth, Development, and Stress Response (Plant Life and Environment Dynamics)
by Anket Sharma Golam Jalal AhammedThis edited book compiles multifaceted functions of melatonin in plant growth, development, and stress response. The main focus of the book is to address the recent most developments in the arena of melatonin-mediated regulation of stress tolerance. Plants are continuously challenged by both biotic and abiotic stressors, which have negative impacts on growth and development. Stimulation of exogenous cues and endogenous signals can help plants to better withstand biotic and abiotic stresses. Melatonin is an important biologically active compound that acts as a multifunctional signaling molecule and regulates key physiological and biochemical processes. Currently, researchers all over the globe have been exploring the in-depth mechanisms of melatonin-modulated regulation of plant biology using various advanced molecular techniques. These recent advancements in melatonin research have possible applications in plant stress management as well as developing stress-tolerant crop varieties. This book is of interest to university teachers, researchers, plant scientists, industry professionals, and policymakers on a global scale.It also serves as a reading material for undergraduate and graduate students of agriculture, forestry, plant biology, and environmental sciences.
Melia and Jo
by Billy AronsonMelia and Jo will be to STEAM what Rosie Revere is to STEM. Melia is scientific and loves to create things in her backyard laboratory, but something is missing. Her inventions just aren&’t quite right. Enter Jo, her new friend with an artistic spirit. When you add the arts to sciences, something magical happens! This whimsically illustrated picture book is the perfect introduction to the benefits of STEAM-focused curriculum.
Mellin-Barnes Integrals: A Primer on Particle Physics Applications (Lecture Notes in Physics #1008)
by Ievgen Dubovyk Janusz Gluza Gábor SomogyiIn this book, the authors discuss the Mellin-Barnes representation of complex multidimensional integrals. Experiments frontiered by the High-Luminosity Large Hadron Collider at CERN and future collider projects demand the development of computational methods to achieve the theoretical precision required by experimental setups. In this regard, performing higher-order calculations in perturbative quantum field theory is of paramount importance. The Mellin-Barnes integrals technique has been successfully applied to the analytic and numerical analysis of integrals connected with virtual and real higher-order perturbative corrections to particle scattering. Easy-to-follow examples with the supplemental online material introduce the reader to the construction and the analytic, approximate, and numeric solution of Mellin-Barnes integrals in Euclidean and Minkowskian kinematic regimes. It also includes an overview of the state-of-the-art software packages for manipulating and evaluating Mellin-Barnes integrals. The book is meant for advanced students and young researchers to master the theoretical background needed to perform perturbative quantum field theory calculations.
Melodías de otros lugares: El tejedor del tiempo - Libro 1
by Cédric FrantzEl equinoccio de primavera se acerca y el invierno está llegando a su fin en Jantival. Kalaen, de once años, lleva una vida ejemplar en su casa familiar. Apasionado por la ciencia y la música, descubre talentos innatos: tiene una percepción inusual del mundo que le rodea. Sus dones extrasensoriales incluso lograron impresionar a su vecino, el anciano alquimista y mago Falchron. Kalaen le tiene un respeto especial y secretamente desea seguir sus pasos. Durante una expedición en el bosque, hace un encuentro inusual y trae a la aldea un objeto misterioso. Con Falchron, intentan entonces desvelar los secretos de esta reliquia que parece datar de tiempos inmemoriales. ¿Cuál es la función de este extraño artefacto? ¿Lograrán descubrirlo? ¿Descubrirán las memorias del tiempo o escucharán el presagio de su fin?
Melt-Quenched Nanocrystals
by null A. M. Glezer null I. E. PermyakovaMelt quenching-the method of quenching from the liquid state-provides new opportunities for producing advanced materials with a unique combination of properties. In the process of melt quenching, attainment of critical cooling rates can produce specific structural states of the material. Nanocrystalline materials produced by melt quenching are clas
Melt Rheology and its Applications in the Plastics Industry
by Jian Wang John M DealyThis is the second edition of Melt Rheology and its Role in Plastics Processing, although the title has changed to reflect its broadened scope. Advances in the recent years in rheometer technology and polymer science have greatly enhanced the usefulness of rheology in the plastics industry. It is now possible to design polymers having specific molecular structures and to predict the flow properties of melts having those structures. In addition, rheological properties now provide more precise information about molecular structure. This book provides all the information that is needed for the intelligent application of rheology in the development of new polymers, the determination of molecular structure and the correlation of processability with laboratory test data. Theory and equations are limited to what is essential for the use of rheology in the characterization of polymers, the development of new plastics materials and the prediction of plastics processing behavior. The emphasis is on information that will be of direct use to practitioners. Extensive references are provided for those wishing to pursue certain issues in greater depth. While the primary audience is applied polymer scientists and plastics engineers, the book will also be of use to postgraduate students in polymer science and engineering and as a text for a graduate course.
Meltdown: Stories of nuclear disaster and the human cost of going critical
by Joel LevyMeltdown investigates and recreates the dramatic events behind the most notorious nuclear accidents in history, as well as those shrouded in secrecy. Combining human tragedy with intriguing science, each account reveals new aspects of humanity's complex relationship with nuclear power and the ongoing struggle to harness and control it. From the pioneers of Los Alamos who got up close and personal with the cores of atomic bombs, to the hapless engineers in Soviet fuel-processing plants who unwittingly mixed up a disaster in a bucket, and from the terrifying impact of a tsunami at Fukushima to the mystery of the recent Russian incident, Meltdown explores the past and future of this extraordinary and potentially lethal source of infinite power.
Meltdown: Stories of nuclear disaster and the human cost of going critical
by Joel LevyMeltdown investigates and recreates the dramatic events behind the most notorious nuclear accidents in history, as well as those shrouded in secrecy. Combining human tragedy with intriguing science, each account reveals new aspects of humanity's complex relationship with nuclear power and the ongoing struggle to harness and control it. From the pioneers of Los Alamos who got up close and personal with the cores of atomic bombs, to the hapless engineers in Soviet fuel-processing plants who unwittingly mixed up a disaster in a bucket, and from the terrifying impact of a tsunami at Fukushima to the mystery of the recent Russian incident, Meltdown explores the past and future of this extraordinary and potentially lethal source of infinite power.
Meltdown: Stories of nuclear disaster and the human cost of going critical
by Joel LevyMeltdown investigates and recreates the dramatic events behind the most notorious nuclear accidents in history, as well as those shrouded in secrecy. Combining human tragedy with intriguing science, each account reveals new aspects of humanity's complex relationship with nuclear power and the ongoing struggle to harness and control it. From the pioneers of Los Alamos who got up close and personal with the cores of atomic bombs, to the hapless engineers in Soviet fuel-processing plants who unwittingly mixed up a disaster in a bucket, and from the terrifying impact of a tsunami at Fukushima to the mystery of the recent Russian incident, Meltdown explores the past and future of this extraordinary and potentially lethal source of infinite power.
Meltdown: Stories of nuclear disaster and the human cost of going critical
by Joel LevyMeltdown investigates and recreates the dramatic events behind the most notorious nuclear accidents in history, as well as those shrouded in secrecy. Combining human tragedy with intriguing science, each account reveals new aspects of humanity's complex relationship with nuclear power and the ongoing struggle to harness and control it. From the pioneers of Los Alamos who got up close and personal with the cores of atomic bombs, to the hapless engineers in Soviet fuel-processing plants who unwittingly mixed up a disaster in a bucket, and from the terrifying impact of a tsunami at Fukushima to the mystery of the recent Russian incident, Meltdown explores the past and future of this extraordinary and potentially lethal source of infinite power.
Melting Away, Pioneer Edition (Explorer Books)
by Glen PhelanNIMAC-sourced textbook <P><P>Learn about why the Earth is heating up and how people can slow the global warming.