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Aptamers for Medical Applications: From Diagnosis to Therapeutics
by Yiyang DongThis book outlines comprehensively the main medical uses of aptamers, from diagnosis to therapeutics in fourteen chapters. Pioneering topics covered include aptamer pharmaceuticals, aptamers for malign tumors, aptamers for personalized therapeutics and aptamers for point-of-care testing. The book offers an essential guide for medical scientists interested in developing aptamer-based schemes for better theranostics. It is therefore of interest for not only academic researchers, but also practitioners and medical researchers in various fields of medical science, medical research and bio-analytical chemistry.
Aptamers in Biotechnology (Advances in Biochemical Engineering/Biotechnology #174)
by Katharina Urmann Johanna-Gabriela WalterThis book reviews the development, characterization and applications of aptamers in different areas of biotechnology ranging from therapeutics to diagnostics and protein purification. Hailed as chemical antibodies, these single-stranded nucleic acid receptors were predicted to supersede antibodies in traditional assays, such as ELISA, within a short time. While this has yet to happen, readers will find in this book a deep insight into the progress of aptamer technology and a critical discussion about the limitations that need to be overcome in order to find wider acceptance and use outside of the still relatively small aptamer-community. This book covers all aspects of aptamer generation and application for the aptamer-experienced reader and curious novice alike, with the addition of an industry perspective on the future of aptamer-use in biotechnology.
Aptamers Selected by Cell-SELEX for Theranostics
by Weihong Tan Xiaohong FangThis edited volume describes cell-SELEX as the fundamental tool used to generate aptamer molecules for a wide range of applications in molecular medicine, bioanalysis and chemical biology. Easily integrated into the natural heterogeneous cell matrix, aptamers can be effectively used in theranostics, bioanalysis, environment detection and biomedical studies. The book gathers reviews that reflect the latest advances in the field of aptamers and consists in fourteen chapters demonstrating essential examples of these aptamers and aptamer-nanomaterial assemblies, depending on the types of applications and biological systems. It also includes a separate chapter on the utilization of aptamers in real clinics and what will be required to achieve this significant goal. The book will be both appealing and useful to a broad audience, including biologists, bioscientists, and clinicians whose interests range from chemistry and biomedical engineering to cell and molecular biology and biotechnology. Weihong Tan is a Distinguished Professor of Chemistry and Biomedical Engineering at Hunan University, China and also a University of Florida Distinguished Professor and V. T. and Louis Jackson Professor of Chemistry at the University of Florida, USA. Xiaohong Fang is a Professor at the Institute of Chemistry, Chinese Academy of Sciences, China.
Aptasensors for Food Safety: Fundamentals and Applications
by Raju Khan Ayushi Singhal Rajan Sharma Y. S RajputThis reference book provides updated knowledge on fundamentals and applications of aptasensorsin food science. It discusses aptamer selection strategies including Systematic Evolution of Ligandsthrough EXponential enrichment (SELEX), Capture SELEX, Cell SELEX, and GO SELEX strategiesfor aptasensor design involving well-studied and newly emerged nanomaterials, food analysisfocusing on its safety, aptasensing techniques relevant to detection of food pathogens, pesticides,veterinary drug residues, toxins, heavy metals, allergens, and future perspectives of aptamers infood science and technology. The book focuses on recent developments in aptasensors and their usein detection of contaminants in food. The book is an excellent resource for R&D organizationsdedicated to the development of biosensors in general and aptasensors in particular for the detectionof environmental contaminants in the food supply chain. Also, the contents of the book willbe useful to researchers, postgraduate students, analytical chemists, food scientists, and regulatoryauthorities.
Aptasensors for Point-of-Care Diagnostics: Fundamentals and Biomedical Applications
by Arpana PariharThe design and fabrication of aptamer-based biosensors for point-of-care testing of disease diagnostic and prognostic is an upthrust and interdisciplinary area of research. This book covers the design and development of novel cost-effective aptamer-based biosensors for disease diagnostic and prognostic including an understanding of health care management in terms of timely updates of disease situations in a particular geographical area. It also discusses the scaling up and market trend of aptamer-based devices for extension of research from lab to market, and end users. Features: Explains the design and fabrication of aptasensors-based diagnostic devices. Includes novel approaches and comprehensive technology overview for diagnosis management towards early-stage detection of various biomarkers associated with several health conditions. Demonstrates possible benefits of combined diagnostics and therapeutic possibilities using aptamer-based point-of-care technologies devices. Discusses emerging implications and recent advances of biosensing platforms for designing and developing aptamer-based point-of-care testing (POCT) devices. Explores aptamer-based approach to develop advanced platforms for medical applications and open arena for state-of-the-art future research. This book is aimed at researchers and graduate students in biomedical engineering, diagnostics, nanobiotechnology, and materials science.
Apun: The Arctic Snow
by Matthew SturmThere are some twenty-five words for “snow” in the Inupiaq language. Each word denotes a different kind of snow—fresh powder snow, hard pack, soft snow, very wet snow, or just snow. Such fine distinction is reasonable, for over the centuries, Natives of the Arctic have had to rely on their knowledge of the snow to survive. Now Matthew Sturm has prepared an educational children’s book designed to teach a new generation of Arctic residents the importance of Arctic snow cover. Fully illustrated to demonstrate the cycle of the snow cover, Apun covers each phase of the “snow year.” Geared towards grades 3–4, this is a must read for elementary science classes.
AQA A Level Biology Student Book 1 (AQA A level Science #22)
by Pauline Lowrie Mark SmithExam Board: AQALevel: AS/A-levelSubject: BiologyFirst Teaching: September 2015First Exam: June 2016AQA ApprovedDevelop students' experimental, analytical and evaluation skills with contemporary and topical biology examples, practical assessment guidance and differentiated end of topic questions, with this AQA Year 1 student book (includes AS-level).- Provides support for all 12 required practicals with plenty of activities and data analysis guidance- Develops understanding with engaging and contemporary examples to help students apply their knowledge, analyse data and evaluate findings- Gives detailed guidance and examples of method with a dedicated 'Maths in Biology' chapter and mathematical support throughout to consolidate learning- Offers regular opportunities to test understanding with Test Yourself Questions, Differentiated End of Topic Questions and Stretch and Challenge Questions- Supports exam preparation with synoptic questions, revision tips and skills- Develops understanding with free online access to 'Test yourself' answers and an extended glossary.
AQA A Level Biology Student Book 2
by Mark Smith Pauline LowrieExam Board: AQALevel: AS/A-levelSubject: BiologyFirst Teaching: September 2015First Exam: June 2017Develop students' experimental, analytical and evaluation skills with contemporary and topical biology examples, practical assessment guidance and differentiated end of topic questions, with this AQA Year 2 student book.- Provides support for all 12 required practicals with plenty of activities and data analysis guidance- Develops understanding with engaging and contemporary examples to help students apply their knowledge, analyse data and evaluate findings- Gives detailed guidance and examples of method with a dedicated 'Maths in Biology' chapter and mathematical support throughout to consolidate learning- Offers regular opportunities to test understanding with Test Yourself Questions, Differentiated End of Topic Questions and Stretch and Challenge Questions- Supports exam preparation with synoptic questions, revision tips and skills-Develops understanding with free online access to 'Test yourself' answers and an extended glossary.
AQA A Level Biology Student Book 2
by Mark Smith Pauline LowrieExam Board: AQALevel: AS/A-levelSubject: BiologyFirst Teaching: September 2015First Exam: June 2017Develop students' experimental, analytical and evaluation skills with contemporary and topical biology examples, practical assessment guidance and differentiated end of topic questions, with this AQA Year 2 student book.- Provides support for all 12 required practicals with plenty of activities and data analysis guidance- Develops understanding with engaging and contemporary examples to help students apply their knowledge, analyse data and evaluate findings- Gives detailed guidance and examples of method with a dedicated 'Maths in Biology' chapter and mathematical support throughout to consolidate learning- Offers regular opportunities to test understanding with Test Yourself Questions, Differentiated End of Topic Questions and Stretch and Challenge Questions- Supports exam preparation with synoptic questions, revision tips and skills-Develops understanding with free online access to 'Test yourself' answers and an extended glossary.
AQA A-level Biology Student Guide: Practical Biology
by Jo OrmisherEnsure your students get to grips with the core practicals and develop the skills needed to succeed with an in-depth assessment-driven approach that builds and reinforces understanding; clear summaries of practical work with sample questions and answers help to improve exam technique in order to achieve higher grades.Written by an experienced teacher, this Student Guide for practical Biology:- Help students easily identify what they need to know with a concise summary of required practical work examined in the A-level specifications.- Consolidate understanding of practical work, methodology, mathematical and other skills out of the laboratory with exam tips and knowledge check questions, with answers in the back of the book.- Provide plenty of opportunities for students to improve exam technique with sample answers, examiners tips and exam-style questions. - Offer support beyond the Student books with coverage of methodologies and generic practical skills not focused on in the textbooks.
AQA A-level Biology Student Guide 3: Topics 5 and 6
by Pauline LowrieWritten by experienced teacher Pauline Lowrie, this Student Guide for Biology:- Identifies the key content you need to know with a concise summary of topics examined in the A-level specifications- Enables you to measure your understanding with exam tips and knowledge check questions, with answers at the end of the guide- Helps you to improve your exam technique with sample answers to exam-style questions- Develops your independent learning skills with content you can use for further study and research
AQA A-level Biology Student Guide 4: Topics 7 and 8
by Pauline LowrieWritten by experienced teacher Pauline Lowrie, this Student Guide for Biology:-Identifies the key content you need to know with a concise summary of topics examined in the A-level specifications-Enables you to measure your understanding with exam tips and knowledge check questions, with answers at the end of the guide-Helps you to improve your exam technique with sample answers to exam-style questions-Develops your independent learning skills with content you can use for further study and research
AQA A-level Biology Student Guide: Practical Biology
by Jo OrmisherExam Board: AQALevel: AS/A-levelSubject: BiologyFirst Teaching: September 2015First Exam: June 2016Ensure your students get to grips with the core practicals and develop the skills needed to succeed with an in-depth assessment-driven approach that builds and reinforces understanding; clear summaries of practical work with sample questions and answers help to improve exam technique in order to achieve higher grades.Written by an experienced teacher, this Student Guide for practical Biology:- Help students easily identify what they need to know with a concise summary of required practical work examined in the A-level specifications.- Consolidate understanding of practical work, methodology, mathematical and other skills out of the laboratory with exam tips and knowledge check questions, with answers in the back of the book.- Provide plenty of opportunities for students to improve exam technique with sample answers, examiners tips and exam-style questions. - Offer support beyond the Student books with coverage of methodologies and generic practical skills not focused on in the textbooks.
AQA A Level Biology (Year 1 and Year 2)
by Pauline Lowrie Mark SmithDevelop experimental, analytical and evaluation skills with topical biology examples, practical assessment guidance and differentiated end-of-topic questions in this updated, all-in-one textbook for Years 1 and 2.Written for the AQA A-level Biology specification, this revised textbook will: - Provide support for all 12 required practicals with plenty of activities and data analysis guidance.- Develop understanding with engaging and contemporary examples to help you apply your knowledge, analyse data and evaluate findings.- Give detailed guidance on the mathematical skills needed with support throughout, examples of method and a dedicated 'Developing mathematical skills' chapter.- Offer regular opportunities to test understanding with 'Test yourself' questions, differentiated end-of-topic questions and 'Stretch and challenge' questions.- Support exam preparation with synoptic questions, revision tips and skills.- Develop understanding with free online access to 'Test yourself' answers, 'Practice' questionanswers and extended glossaries*.
AQA A Level Biology (Year 1 and Year 2)
by Pauline Lowrie Mark SmithDevelop experimental, analytical and evaluation skills with topical biology examples, practical assessment guidance and differentiated end-of-topic questions in this updated, all-in-one textbook for Years 1 and 2.Written for the AQA A-level Biology specification, this revised textbook will: - Provide support for all 12 required practicals with plenty of activities and data analysis guidance.- Develop understanding with engaging and contemporary examples to help you apply your knowledge, analyse data and evaluate findings.- Give detailed guidance on the mathematical skills needed with support throughout, examples of method and a dedicated 'Developing mathematical skills' chapter.- Offer regular opportunities to test understanding with 'Test yourself' questions, differentiated end-of-topic questions and 'Stretch and challenge' questions.- Support exam preparation with synoptic questions, revision tips and skills.- Develop understanding with free online access to 'Test yourself' answers, 'Practice' questionanswers and extended glossaries*.
AQA A Level Chemistry Student Book 1
by Nora Henry Teresa Quigg Alyn G. McFarlandAQA ApprovedHelp students to apply and develop their knowledge, progressing from basic concepts to more complicated Chemistry, with worked examples, practical activities and mathematical support throughout- Provides support for all 12 required practicals with activities that introduce practical work and other experimental investigations in Chemistry- Offers detailed examples to help students get to grips with difficult concepts such as Physical Chemistry calculations- Mathematical skills are integrated throughout the book and all summarised in one chapter for easy reference- Allows you to easily measure progression with Differentiated End of Topic questions and Test Yourself Questions- Develops understanding with free online access to Test yourself Answers, an Extended Glossary, Learning Outcomes and Topic SummariesAQA A-level Chemistry Year 1 includes AS-level.
AQA A Level Chemistry Student Book 1
by Alyn G. McFarland Teresa Quigg Nora HenryExam Board: AQALevel: AS/A-levelSubject: ChemistryFirst Teaching: September 2015First Exam: June 2016AQA ApprovedHelp students to apply and develop their knowledge, progressing from basic concepts to more complicated Chemistry, with worked examples, practical activities and mathematical support throughout- Provides support for all 12 required practicals with activities that introduce practical work and other experimental investigations in Chemistry- Offers detailed examples to help students get to grips with difficult concepts such as Physical Chemistry calculations- Mathematical skills are integrated throughout the book and all summarised in one chapter for easy reference- Allows you to easily measure progression with Differentiated End of Topic questions and Test Yourself Questions-Develops understanding with free online access to 'Test yourself' answers and an extended glossary.AQA A-level Chemistry Year 1 includes AS-level.
AQA A Level Chemistry Student Book 1
by Alyn G. McFarland Teresa Quigg Nora HenryExam Board: AQALevel: AS/A-levelSubject: ChemistryFirst Teaching: September 2015First Exam: June 2016AQA ApprovedHelp students to apply and develop their knowledge, progressing from basic concepts to more complicated Chemistry, with worked examples, practical activities and mathematical support throughout- Provides support for all 12 required practicals with activities that introduce practical work and other experimental investigations in Chemistry- Offers detailed examples to help students get to grips with difficult concepts such as Physical Chemistry calculations- Mathematical skills are integrated throughout the book and all summarised in one chapter for easy reference- Allows you to easily measure progression with Differentiated End of Topic questions and Test Yourself Questions-Develops understanding with free online access to 'Test yourself' answers and an extended glossary.AQA A-level Chemistry Year 1 includes AS-level.
AQA A Level Chemistry Student Book 2
by Nora Henry Alyn G. McfarlandAQA Approved'Mathematical skills are integrated throughout the text and the examples provide clear and logical stages in working. The dedicated mathematics in Chemistry section provides a very useful revision tool when a student wants to be sure they are at ease with all the types of mathematical calculation they may be asked to carry out.' A. Popperwell, Science TeacherHelp students to apply and develop their knowledge, progressing from basic concepts to more complicated Chemistry, with worked examples, practical activities and mathematical support throughout. - Provides support for all 12 required practicals with activities that introduce practical work and other experimental investigations in Chemistry- Offers detailed examples to help students get to grips with difficult concepts such as Physical Chemistry calculations- Mathematical skills are integrated throughout the book and all summarised in one chapter for easy reference- Allows you to easily measure progression with Differentiated End of Topic questions and Test Yourself Questions- Develops understanding with free online access to Test yourself Answers, an Extended Glossary, Learning Outcomes and Topic Summaries
AQA A Level Chemistry Student Book 2
by Alyn G. McFarland Nora HenryExam Board: AQALevel: AS/A-levelSubject: ChemistryFirst Teaching: September 2015First Exam: June 2017AQA ApprovedHelp students to apply and develop their knowledge, progressing from basic concepts to more complicated Chemistry, with worked examples, practical activities and mathematical support throughout. - Provides support for all 12 required practicals with activities that introduce practical work and other experimental investigations in Chemistry- Offers detailed examples to help students get to grips with difficult concepts such as Physical Chemistry calculations- Mathematical skills are integrated throughout the book and all summarised in one chapter for easy reference- Allows you to easily measure progression with Differentiated End of Topic questions and Test Yourself Questions- Develops understanding with free online access to 'Test yourself' answers and an extended glossary.
AQA A Level Chemistry Student Book 2
by Alyn G. McFarland Nora HenryExam Board: AQALevel: AS/A-levelSubject: ChemistryFirst Teaching: September 2015First Exam: June 2017AQA ApprovedHelp students to apply and develop their knowledge, progressing from basic concepts to more complicated Chemistry, with worked examples, practical activities and mathematical support throughout. - Provides support for all 12 required practicals with activities that introduce practical work and other experimental investigations in Chemistry- Offers detailed examples to help students get to grips with difficult concepts such as Physical Chemistry calculations- Mathematical skills are integrated throughout the book and all summarised in one chapter for easy reference- Allows you to easily measure progression with Differentiated End of Topic questions and Test Yourself Questions- Develops understanding with free online access to 'Test yourself' answers and an extended glossary.
AQA A-level Chemistry Student Guide: Practical Chemistry
by Nora HenryEnsure your students get to grips with the core practicals and develop the skills needed to succeed with an in-depth assessment-driven approach that builds and reinforces understanding; clear summaries of practical work with sample questions and answers help to improve exam technique in order to achieve higher grades.Written by experienced teachers Tim Waite and Amber Waite, this Student Guide for practical Chemistry:- Help students easily identify what they need to know with a concise summary of required practical work examined in the A-level specifications.- Consolidate understanding of practical work, methodology, mathematical and other skills out of the laboratory with exam tips and knowledge check questions, with answers in the back of the book.- Provide plenty of opportunities for students to improve exam technique with sample answers, examiners tips and exam-style questions. - Offer support beyond the Student books with coverage of methodologies and generic practical skills not focused on in the textbooks.
AQA A-level Chemistry Student Guide 3: Physical chemistry 2
by Nora Henry Alyn G. McfarlandWritten by experienced examiners Alyn McFarland and Nora Henry, this Student Guide for Chemistry:- Helps students identify what they need to know with a concise summary of the topics examined in the AS and A-level specifications- Consolidates understanding with tips and knowledge check questions- Provides opportunities to improve exam technique with sample answers to exam-style questions- Develops independent learning and research skills- Provides the content for generating individual revision notes
AQA A-level Chemistry Student Guide: Practical Chemistry
by Nora HenryExam Board: AQALevel: AS/A-levelSubject: ChemistryFirst Teaching: September 2015First Exam: June 2016Ensure your students get to grips with the core practicals and develop the skills needed to succeed with an in-depth assessment-driven approach that builds and reinforces understanding; clear summaries of practical work with sample questions and answers help to improve exam technique in order to achieve higher grades.Written by experienced author Nora Henry, this Student Guide for practical Chemistry:- Help students easily identify what they need to know with a concise summary of required practical work examined in the A-level specifications.- Consolidate understanding of practical work, methodology, mathematical and other skills out of the laboratory with exam tips and knowledge check questions, with answers in the back of the book.- Provide plenty of opportunities for students to improve exam technique with sample answers, examiners tips and exam-style questions. - Offer support beyond the Student books with coverage of methodologies and generic practical skills not focused on in the textbooks.
AQA A Level Chemistry (Year 1 and Year 2)
by Alyn G. McFarland Nora Henry Teresa QuiggDevelop and learn to apply your knowledge, progressing from basic concepts to more complicated Chemistry, with worked examples, practical activities and mathematical support in this updated, all-in-one textbook for Years 1 and 2.Written for the AQA A-level Chemistry specification, this revised textbook will:- Provide support for all 12 required practicals with activities that introduce practical work and other experimental investigations in Chemistry.- Offer detailed examples to help you get to grips with difficult concepts such as physical chemistry calculations.- Helps to improve mathematical skills with support throughout, examples of method and a dedicated 'Maths for chemistry' chapter.- Allow you to easily measure progression with differentiated end-of-topic questions and 'Test yourself' questions.- Develop understanding with free online access to 'Test yourself' answers, 'Practice' question answers and extended glossaries*.