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Metabolomics and Systems Biology in Human Health and Medicine
by Baljit Ubhi Mahon Maguire Reza Salek Jacqueline Wood Luigi Atzori Jonathan Swann Lee Roberts Aalim Welji Julian Griffin Daniel DiasThe metabolomics and systems biology approach to research can be applied to many disciplines. This book provides a solid introduction to medical metabolomics and systems biology, and demonstrates how they have been applied to studies in medicine and human health, including nutrition and pathogenic microorganisms. Following core themes of diagnosis, pathology and aetiology of disease, this book provides a reference for health care professionals interested in how to use metabolomics for medical research.
Metabolomics in Practice
by Michael Lämmerhofer Wolfram WeckwerthUnlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation. By systematically covering the entire workflow, from sample preparation to data processing, the insight and advice offered here helps to clear the hurdles in setting up and running a successful analysis, resulting in high-quality data from every experiment.Based on more than a decade of practical experience in developing, optimizing and validating metabolomics approaches as a routine technology in the academic and industrial research laboratory, the lessons taught here are highly relevant for all systems-level approaches, whether in systems biology, biotechnology, toxicology or pharmaceutical sciences.From the Contents:* Sampling and Sample Preparation in Microbial Metabolomics* Tandem Mass Spectrometry Hyphenated with HPLC and UHPLC for Targeted Metabolomics* GC-MS, LC-MS, CE-MS and Ultrahigh Resolution MS (FTICR-MS) in Metabolomics * NMR-based metabolomics analysis* Potential of Microfluidics and Single Cell Analysis in Metabolomics * Data Processing in Metabolomics* Validation and Measurement Uncertainty in Metabolomic Studies* Metabolomics and its Role in the Study of Mammalian Systems and in Plant Sciences* Metabolomics in Biotechnology and Nutritional Metabolomicsand more.
Metabolomics, Proteomes and Gene Editing Approaches in Biofertilizer Industry
by Sukhminderjit Kaur Vagish Dwibedi Pramod Kumar Sahu Gurvinder Singh KocherThis edited book covers the major aspects of plant growth promoting bacteria and mechanisms underlining the phenotype in rhizobacteria. This book guides the researchers about the potential of plant growth promoting bacteria to be used as biofertilizers. The process of biofertilizer development and the process of testing its efficacy for commercial use and the potency is elaborated in this volume using suitable figures. The information in this book regarding the secretion of various secondary metabolites responsible for nutrient management is helpful for designing bioformulations that assist plant growth. This book provides substantial number of evidences that underlines the genomic basis of nutrient management by microbes. Essential information is provided regarding the genomic and proteomic background of the biofertilizers. The chapters in the book are divided into three sections. The first section of the book includes chapter 1-5 outlining the importance of rhizobacteria in elevating the nutrient levels in soil and augmenting the biotic and abiotic stress. Second section of the book includes chapter 6-11 elaborating the details about the biofertilizer, types of biofertilizer available and techniques involved in mass production of biofertilizers. Section third covers chapters from 12-15 providing the explicit information about metabolomics and proteomics basis of plant growth development. This collective work is distinct as it has focus on diverse emerging technologies which are high-throughput, scalable and applicable to different countries regardless of their socio-economic conditions. This book can improve the current state of knowledge and invoke researchers and innovators to take ahead the current inter-disciplinary knowledge into technologies that are readily available and effectively minimize hazards associated with chemical fertilizer.
Metabolomics, Proteomics and Gene Editing Approaches in Biofertilizer Industry: Volume II
by Pramod Kumar Sahu Vagish Dwibedi Sukhminderjit KaurBiofertilizer refers to the live or latent microbial inoculants capable of enhancing plant growth through direct and indirect mechanisms. This book covers strategies for harnessing the integrated technologies, omics, proteomics, and metabolomics for the development of potential novel biofertilizers. Modern techniques for enhancing the efficacy and quality of biofertilizers has been discussed in detail. Increasing crop productivity poses a great challenge due to increasing global population and researchers are looking for solutions to this using sustainable approaches. Biofertilizers play an imperative role in enhancing yield production in crops and this book covers detailed account of biofertilizers on a single platform. It also provides guidance on sustainable ways of increasing crop production and helps in generating ideas to formulate collaboration between public and private sectors for future innovation in the field of biofertilizers.This book is especially designed for the research graduates, young researchers and scholars who are directly involved in the research-related activities of the biofertilizers. It can also be useful to professors, lecturers, biotechnologists, biofertilizer production specialists and other stakeholders associated with strain improvement for biofertilizer development.
Metabolomics Tools for Natural Product Discovery: Methods and Protocols
by Daniel Anthony Dias Ute RoessnerClassical natural product chemistry is transitioning to modern day metabolomics as a result of the advent of comprehensive analytical platforms and sensitive analytical instrumentation. Therefore, it is worthwhile to summarize recent developments with current analytical platforms and highlight how metabolomics is being integrated into this classical field to dereplicate and profile natural product extracts. Metabolomics Tools for Natural Product Discoveries: Methods and Protocols aims to unite diverse and recently developed methodologies and protocols in order to identify bioactive secondary metabolites for the purpose of drug discovery. Some topics covered in this volume include applications for the extraction of selected natural products from less common sources such as bryophytes and hard corals, various biological assays, comprehensive applications and strategies for GC-MS, LC-MS, and NMR, as well as protocols and strategies for the structure elucidation of isolated natural products. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible Metabolomics Tools for Natural Product Discoveries: Methods and Protocols seeks to serve both professionals and research students with its well-honed methodologies for natural product isolation, biomarker discovery, dereplication, biological assays, and comprehensive metabolomic platforms available for high-throughput analyses.
Metabonomics
by Jacob T. BjerrumThis volume on metabonomics provides detailed information on the procedures involved in nuclear magnetic resonance (NMR) spectroscopy, gas chromatography-mass spectrometry (GS-MS), liquid chromatography-mass spectrometry (LC-MS), and capillary electrophoresis-mass spectrometry (CE-MS). Chapters focus on technologies and chemometrics, generation of metabonomics data, extraction of meaningful information from data, drug development, toxicology, diagnostics, and describing metabonomics as an essential part of systems biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Metabotropic GPCRs: TGR5 and P2Y Receptors in Health and Diseases
by Senthilkumar Rajagopal Murugavel PonnusamyThis book will provide current understandings about two ubiquitously expressed metabotropic GPCRs, G-coupled purinoreceptor type 2 (P2Y) and Takeda G-protein-coupled bile acid receptor 5 (TGR5). G protein coupled receptors (GPCRs) are the largest family of proteins implicated in majority of cellular responses. The two receptor sub-families play a central role in many physiological functions as well as in many pathological conditions. This book offers up-to-date information on the physiological functions, signaling pathways and regulatory mechanisms of P2Y and TGR5 receptors. In addition, this book provides a comprehensive overview about the abnormalities of P2Y/TGR5 receptors and their contribution in the development and progression of pathological conditions. It also covers the currently available natural, chemical and pharmacological agents targeting these two receptor families and their therapeutic implications in P2Y and TGR5 associated disorders. This book is a valuable source for beginners and researchers to follow the rapidly progressing field of these two GPCR subfamily members.
Metacognition and Cognitive Neuropsychology: Monitoring and Control Processes
by Giuliana Mazzoni Thomas O. NelsonControl processes are those mental functions that allow us to initiate, monitor, and prioritize mental activities. They are crucial to normal mental functioning. A better understanding of the nature of control processes and their deficits is important for clinical work and for an adequate theory of consciousness. Previously, control processes have been examined within the frameworks of two parallel but independent paradigms: those of cognitive psychology and of neuropsychology. Cognitive psychologists have stressed the theoretical and empirical nature of normal unimpaired control processes; neuropsychologists have focused on the relationships between damage to specific functional areas of the brain and deficits in specific control processes. Both have contributed extensively to our understanding of control processes. However, they have tended to operate independently, with little if any cross-talk between disciplines, despite the potential benefits such dialogue is likely to generate. This book represents the first attempt to synthesize cognitive and neuropsychological perspectives on control processes. It contains state-of-the-art reports on various aspects of control processes by experts from both disciplines.
Metacognition in Science Education
by Anat Zohar Yehudit Judy DoriWhy is metacognition gaining recognition, both in education generally and in science learning in particular? What does metacognition contribute to the theory and practice of science learning? Metacognition in Science Education discusses emerging topics at the intersection of metacognition with the teaching and learning of science concepts, and with higher order thinking more generally. The book provides readers with a background on metacognition and analyses the latest developments in the field. It also gives an account of best-practice methodology. Expanding on the theoretical underpinnings of metacognition, and written by world leaders in metacognitive research, the chapters present cutting-edge studies on how various forms of metacognitive instruction enhance understanding and thinking in science classrooms. The editors strive for conceptual coherency in the various definitions of metacognition that appear in the book, and show that the study of metacognition is not an end in itself. Rather, it is integral to other important constructs, such as self-regulation, literacy, the teaching of thinking strategies, motivation, meta-strategies, conceptual understanding, reflection, and critical thinking. The book testifies to a growing recognition of the potential value of metacognition to science learning. It will motivate science educators in different educational contexts to incorporate this topic into their ongoing research and practice.
Metacommunity Ecology, Volume 59
by Mathew A. Leibold Jonathan M. ChaseMetacommunity ecology links smaller-scale processes that have been the provenance of population and community ecology—such as birth-death processes, species interactions, selection, and stochasticity—with larger-scale issues such as dispersal and habitat heterogeneity. Until now, the field has focused on evaluating the relative importance of distinct processes, with niche-based environmental sorting on one side and neutral-based ecological drift and dispersal limitation on the other. This book moves beyond these artificial categorizations, showing how environmental sorting, dispersal, ecological drift, and other processes influence metacommunity structure simultaneously.Mathew Leibold and Jonathan Chase argue that the relative importance of these processes depends on the characteristics of the organisms, the strengths and types of their interactions, the degree of habitat heterogeneity, the rates of dispersal, and the scale at which the system is observed. Using this synthetic perspective, they explore metacommunity patterns in time and space, including patterns of coexistence, distribution, and diversity. Leibold and Chase demonstrate how these processes and patterns are altered by micro- and macroevolution, traits and phylogenetic relationships, and food web interactions. They then use this scale-explicit perspective to illustrate how metacommunity processes are essential for understanding macroecological and biogeographical patterns as well as ecosystem-level processes.Moving seamlessly across scales and subdisciplines, Metacommunity Ecology is an invaluable reference, one that offers a more integrated approach to ecological patterns and processes.
Metagenomic Data Analysis (Methods in Molecular Biology #2649)
by Suparna MitraThis volume describes different sequencing methods, pipelines and tools for metagenome data analyses. Chapters guide readers through quality control of raw sequence data, metagenomics databases for bacterial annotations such Greengenes, SILVA, RDP and GTDB, guide to 16S rRNA microbiome analysis and pipelines such as mothur, DADA2, QIIME2 , whole genome shotgun metagenomics data analyses pipeline using MEGAN and DIAMOND, web service such as PATRIC, RDP, mothur, Kaiju, PhyloPythiaS, MG-RAST, WebMGA, MicrobiomeAnalyst, WHAM!, METAGENassist and MGnify: EBI-Metagenomics, MG-RAST Metagenomics Analysis. Then the chapters inform the readers regarding Third-generation sequencing (TGS) approaches as MinION sequencing and teaches use of Ubuntu Linux Virtual Machine configuration, clinical and environmental resistomes, use of FISH techniques and designing FISH probes, protocols for viral metagenomics, and comprehensive guideline for microbiome analysis using most used R packages. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and methods, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Metagenomic Data Analysis: Methods and Protocols aims to be comprehensive guide for researchers to specialize in the metagenomics field.
Metagenomic Systems Biology: Integrative Analysis of the Microbiome
by Shailza SinghThe book serves as an amalgamation of knowledge and principles used in the area of systems and synthetic biology, and targets inter-disciplinary research groups. The readers from diversified areas would be benefited by the valuable resources and information available in one book. Microbiome projects with efficient data handling can fuel progress in the area of microbial synthetic biology by providing a ready to use plug and play chassis. Advances in gene editing technology such as the use of tailor made synthetic transcription factors will further enhance the availability of synthetic devices to be applied in the fields of environment, agriculture and health. The different chapters of the book reviews a broad range of topics, including food microbiome in ecology, use of microbiome in personalized medicine, machine learning in biomedicine. The book also describes ways to harness and exploit the incredible amounts of genomic data. The book is not only limited to medicine but also caters to the needs of environmentalists, biochemical engineers etc. It will be of interest to advanced students and researchers in life sciences, computational biology, microbiology and other inter-disciplinary areas.
Metagenomics
by Rolf Daniel Wolfgang R. StreitMetagenomics has proven to be a powerful tool for exploring the ecology, metabolic profiling, and comparison of complex microbial communities as well as its important applications in the mining of metagenomes for genes encoding novel biocatalysts and drug molecules for bioindustries. In Metagenomics: Methods and Protocols, expert researches provide an overview and introduction to basic methods commonly used in laboratories that have a strong background in microbial metagenomics. The book attempts to address all of the working steps involved in this crucial field, beginning with DNA isolation from soils and marine samples and continuing with the construction and screening of libraries, along with key advise involving bioinformatic tools available to analyze large metagenomic sequence data sets. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Metagenomics: Methods and Protocols serves as a very complete guide to available screening protocols for all major biocatalysts in order to allow for the easy setup of these screens in any microbiology lab.
Metagenomics
by Wolfgang R. Streit Rolf DanielThis second edition explores up-to-date tools in various function-based technologies currently used in metagenomics. The chapters in this book discuss all of the working steps involved in these technologies, such as: DNA isolation from soils and marine samples followed by the construction and screening of libraries for diverse enzymes and biomolecules; current methods used to isolate DNA and construct large- and small-insert libraries from terrestrial and marine habitats; methods for establishing metagenome libraries in none-E. coli hosts; new molecular tools used for function-driven mining of metagenomic DNA; and screening protocols for a wide array of different genes encoding enzymes with relevance to biotechnology and ecology. Metagenomics: Methods and Protocols, Second Edition also provides detailed screening protocols for phosphatases, poly-hydroxyalkanoate, metabolism-related enzymes, stereoselective hydrolases, and microbial signals for the discovery of secondary metabolites. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Metagenomics: Methods and Protocols, Second Edition is a collection of up-to-date metagenome protocols and tools for the recovery of numerous major types of biocatalysts, and allows researchers to easily setup these screens in any microbiology laboratory.
Metagenomics: Methods and Protocols (Methods in Molecular Biology #2555)
by Wolfgang R. Streit Rolf DanielThis volume provides up-to-date and novel techniques for various screening technologies currently used in metagenomics and related areas. Starting with DNA/RNA isolation from environmental samples, the book continues by delving into areas such as current methods used to isolate DNA and construct metagenomic libraries, establishment of metagenome libraries in non-E. coli hosts, and topics like function-driven mining of metagenomic DNA, screening and analyzing protocols for a wide array of different genes encoding enzymes, bacterial viruses and much more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Metagenomics: Methods and Protocols, Third Edition provides a comprehensive collection of up-to-date metagenome protocols and tools for the recovery of many major types of biocatalysts and allows for the easy setup of these screens in microbiology laboratories.
Metagenomics and Microbial Ecology: Techniques and Applications
by Surajit De Mandal Amrita Kumari Panda Nachimuthu Senthil Kumar Satpal Singh Bisht Fengliang JinMicroorganisms comprise the greatest genetic diversity in the natural ecosystem, and characterization of these microbes is an essential step towards discovering novel products or understanding complex biological mechanisms. The advancement of metagenomics coupled with the introduction of high-throughput, cost-effective NGS technology has expanded the possibilities of microbial research in various biological systems. In addition to traditional culture and biochemical characteristics, omics approaches (metagenomics, metaproteomics, and metatranscriptomics) are useful for analyzing complete microbial communities and their functional attributes in various environments. Metagenomics and Microbial Ecology: Techniques and Applications explores the most recent advances in metagenomics research in the landscape of next-generation sequencing technologies. This book also describes how advances in sequencing technologies are used to study invisible microbes as well as the relationships between microorganisms in their respective environments. Features: Covers a wide range of concepts, investigations, and technological advancement in metagenomics at the global level. Highlights the novel and recent approaches to analyze microbial diversity and its functional attributes. Features a range of chapters that present an introduction to the field and functional insight into various ecosystems.
Metagenomics of the Human Body
by Karen E. NelsonThe book brings a completely different perspective than available books by combining the information gained from the human genome with that derived from parallel metagenomic studies, and new results from investigating the effects of these microbes on the host immune system. Although there are a number of books that focus on the human genome that are currently available, there are no books that bring to the forefront the mix of the human genome and the genomes and metagenomes of the microbial species that live within and on us.
Metagenomics: Techniques, Applications, Challenges and Opportunities
by Reena Singh Chopra Chirag Chopra Neeta Raj SharmaThis book summarizes the various areas of research in metagenomics and their potential applications in medicine, the environment and biotechnology. The book presents the recent advances in theoretical, methodological and applied aspects of metagenomics and highlights their applications in the fields of environmental microbial forensics, bioremediation, drug-discovery and agriculture. In addition, the book discusses various metagenomics approaches used for understanding the microbial physiology and biochemistry. Lastly the book describes a range of bioinformatics tools and computational methods for metagenomics analysis as well as the functional diversity and dynamics of microbial communities colonizing the human skin.
Metagovernance for Sustainability: A Framework for Implementing the Sustainable Development Goals (Routledge Studies in Sustainable Development)
by Louis MeulemanThe 17 Sustainable Development Goals (SDGs) which were adopted by the United Nations in September 2015 are universally applicable in all 193 UN Member States and connect the big challenges of our time, such as hunger and poverty, climate change, health in an urbanised environment, sustainable energy, mobility, economic development and environmental degradation. Sustainability has the characteristics of a ‘wicked problem’, for which there are no one-size-fits-all solutions. This book tests the hypothesis that the implementation of sustainable development, and in particular the 2015 SDGs, requires tailor-made metagovernance or ‘governance of governance’. This is necessary to develop effective governance and high quality and inclusive public administration and to foster policy and institutional coherence to support implementing the SDGs. Based on the growing literature on governance and metagovernance, and taking into account the specificities of societal factors such as different values and traditions in different countries, the book presents a framework for the design and management of SDG implementation. It shows how hierarchical, network and market governance styles can be combined and how governance failure can be prevented or dealt with. The book presents an overview of fifty ‘shades of governance’ which differ for each governance style, and a sketch of a concrete method to apply sustainability metagovernance. Metagovernance for Sustainability is relevant to academic and practitioner fields across many disciplines and problem areas. It will be of particular interest to scholars, students and policy-makers studying Sustainable Development, Governance and Metagovernance, Public Management and Capacity Building.
A Metaheuristic Approach to Protein Structure Prediction: Algorithms And Insights From Fitness Landscape Analysis (Emergence, Complexity And Computation Ser. #31)
by Nanda Dulal Jana Swagatam Das Jaya SilThis book introduces characteristic features of the protein structure prediction (PSP) problem. It focuses on systematic selection and improvement of the most appropriate metaheuristic algorithm to solve the problem based on a fitness landscape analysis, rather than on the nature of the problem, which was the focus of methodologies in the past. Protein structure prediction is concerned with the question of how to determine the three-dimensional structure of a protein from its primary sequence. Recently a number of successful metaheuristic algorithms have been developed to determine the native structure, which plays an important role in medicine, drug design, and disease prediction. This interdisciplinary book consolidates the concepts most relevant to protein structure prediction (PSP) through global non-convex optimization. It is intended for graduate students from fields such as computer science, engineering, bioinformatics and as a reference for researchers and practitioners.
Metaheuristics for Resource Deployment under Uncertainty in Complex Systems
by Panos M. Pardalos Qi Zhang Chen Chen Shuxin Ding Bin XinMetaheuristics for Resource Deployment under Uncertainty in Complex Systems analyzes how to set locations for the deployment of resources to incur the best performance at the lowest cost. Resources can be static nodes and moving nodes while services for a specific area or for customers can be provided. Theories of modeling and solution techniques are used with uncertainty taken into account and real-world applications used. The authors present modeling and metaheuristics for solving resource deployment problems under uncertainty while the models deployed are related to stochastic programming, robust optimization, fuzzy programming, risk management, and single/multi-objective optimization. The resources are heterogeneous and can be sensors and actuators providing different tasks. Both separate and cooperative coverage of the resources are analyzed. Previous research has generally dealt with one type of resource and considers static and deterministic problems, so the book breaks new ground in its analysis of cooperative coverage with heterogeneous resources and the uncertain and dynamic properties of these resources using metaheuristics. This book will help researchers, professionals, academics, and graduate students in related areas to better understand the theory and application of resource deployment problems and theories of uncertainty, including problem formulations, assumptions, and solution methods.
Metahuman: Unleashing Your Infinite Potential
by Deepak ChopraIs it possible to venture beyond daily living and experience heightened states of awareness? In his latest book, Deepak Chopra says that higher consciousness is available here and now. “Metahuman helps us harvest peak experiences so we can see our truth and mold the universe’s chaos into a form that brings light to the world.”—Dr. Mehmet Oz, Attending Physician, New York–Presbyterian, Columbia University New York Times bestselling author Deepak Chopra unlocks the secrets to moving beyond our present limitations to access a field of infinite possibilities. How does one do this? By becoming metahuman. To be metahuman, however, isn’t science fiction and is certainly not about being a superhero. To be metahuman means to move past the limitation constructed by the mind and enter a new state of awareness where we have deliberate and concrete access to peak experiences that can transform people’s lives from the inside out. Humans do this naturally—to a point. For centuries the great artists, scientists, writers, and many so-called ordinary people have gone beyond the everyday physical world. But if we could channel these often bewildering experiences, what would happen? Chopra argues we would wake up to experiences that would blow open your body, mind, and soul. Metahuman invites the reader to walk the path here and now. Waking up, we learn, isn’t just about mindfulness or meditation. Waking up, to become metahuman, is to expand our consciousness in all that we think, say, and do. By going beyond, we liberate ourselves from old conditioning and all the mental constructs that underlie anxiety, tension, and ego-driven demands. Waking up allows life to make sense as never before. To make this as practical as possible, Chopra ends the book with a 31-day guide to becoming metahuman. Once you wake up, he writes, life becomes transformed, because pure consciousness—which is the field of all possibilities—dawns in your life. Only then does your infinite potential become your personal reality.Advance praise for Metahuman“Our world is preoccupied with material progress, yet too often we overlook the miracle of our very existence. In this remarkable book, Deepak Chopra reminds us not to be distracted by the idols of our age but to marvel at the deep truths of being. Metahuman is a handbook to becoming fully alive.”—Arthur C. Brooks, PhD, Professor, Harvard Kennedy School; author of Love Your Enemies
Metakaolin and Fly Ash as Mineral Admixtures for Concrete
by Leonid Dvorkin Vadim Zhitkovsky Yuri Ribakov Nataliya LushnikovaThe book deals with modern theoretical concepts related to the impact of fly ash and metakaolin admixtures on structure formation processes of concrete. Results of the effect of fly ash, metakaolin and their composition on properties of self-compacting and self-leveling concrete are presented. Based on mathematical models, obtained using mathematical experiments planning methodology, the impact of the main factors and their combination on workability, strength and other properties that determine efficiency and durability of concrete are analyzed. Using calculated dependencies, a methodology for designing optimal compositions of concrete containing active mineral admixtures and superplasticizers is proposed. Features of industrial production of concrete for the proposed compositions are discussed. The book is intended for specialists working in the production of concrete and reinforced concrete products and elements. It can also be used by construction engineers to design compositions of cost-effective self-compacting and self-leveling concrete as well as to determine the rational direction of using technogenic raw materials like ash and metakaolin.
Metal Additive Manufacturing
by Ehsan Toyserkani Dyuti Sarker Osezua Obehi Ibhadode Farzad Liravi Paola Russo Katayoon TaherkhaniMETAL ADDITIVE MANUFACTURING A comprehensive review of additive manufacturing processes for metallic structures Additive Manufacturing (AM)—also commonly referred to as 3D printing—builds three-dimensional objects by adding materials layer by layer. Recent years have seen unprecedented investment in additive manufacturing research and development by governments and corporations worldwide. This technology has the potential to replace many conventional manufacturing processes, enable the development of new industry practices, and transform the entire manufacturing enterprise. Metal Additive Manufacturing provides an up-to-date review of all essential physics of metal additive manufacturing techniques with emphasis on both laser-based and non-laser-based additive manufacturing processes. This comprehensive volume covers fundamental processes and equipment, governing physics and modelling, design and topology optimization, and more. The text adresses introductory, intermediate, and advanced topics ranging from basic additive manufacturing process classification to practical and material design aspects of additive manufacturability. Written by a panel of expert authors in the field, this authoritative resource: Provides a thorough analysis of AM processes and their theoretical foundations Explains the classification, advantages, and applications of AM processes Describes the equipment required for different AM processes for metallic structures, including laser technologies, positioning devices, feeder and spreader mechanisms, and CAD software Discusses the opportunities, challenges, and current and emerging trends within the field Covers practical considerations, including design for AM, safety, quality assurance, automation, and real-time control of AM processes Includes illustrative cases studies and numerous figures and tables Featuring material drawn from the lead author’s research and professional experience on laser additive manufacturing, Metal Additive Manufacturing is an important source for manufacturing professionals, research and development engineers in the additive industry, and students and researchers involved in mechanical, mechatronics, automatic control, and materials engineering and science.
Metal-Air and Metal-Sulfur Batteries: Fundamentals and Applications (Electrochemical Energy Storage and Conversion)
by Vladimir Neburchilov and Jiujun ZhangMetal–air and metal–sulfur batteries (MABs/MSBs) represent one of the most efficient-energy storage technologies, with high round trip efficiency, a long life cycle, fast response at peak demand/supply of electricity, and decreased weight due to the use of atmospheric oxygen as one of the main reactants. This book presents an overview of the main MABs/MSBs from fundamentals to applications. Recent technological trends in their development are reviewed. It also offers a detailed analysis of these batteries at the material, component, and system levels, allowing the reader to evaluate the different approaches of their integration. The book provides a systematic overview of the components, design, and integration, and discusses current technologies, achievements, and challenges, as well as future directions. Each chapter focuses on a particular battery type including zinc–air batteries, lithium–air batteries, aluminum–air batteries, magnesium–air batteries, lithium–sulfur batteries, and vanadium–air redox flow batteries, and metal–sulfur batteries. Features the most recent advances made in metal–air/metal–sulfur batteries. Describes cutting-edge materials and technology for metal–air/metal–sulfur batteries. Includes both fundamentals and applications, which can be used to guide and promote materials as well as technology development for metal–air/metal–sulfur batteries. Provides a systematic overview of the components, design, and integration, and discusses current technologies, achievements, and challenges, as well as future directions. Covers a variety of battery types in depth, such as zinc–air batteries, lithium–air batteries, aluminum–air batteries, magnesium–air batteries, lithium–sulfur batteries, vanadium–air redox flow batteries, and metal–sulfur batteries.