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Noncoding RNAs and Bone
by Ye Tian Airong QianThe book provides an in-depth and comprehensive overview of the essential role of non-coding RNAs (ncRNAs) in bone formation. In combination with researches from multiple scholars in this field, the book reviews the mechanisms of ncRNA-related bone diseases, as well as the potential applications of RNA synthesis technology in bone disorder treatments. This volume covers the following topics: 1) basic introduction of non-coding RNA and bone development, how 2) microRNAs and 3) long noncoding RNAs (LncRNAs) regulate bone formation, 4) how ncRNAs and the corresponding pathways participate in bone metabolism diseases, 5) RNA synthesis technology and the possible RNA therapies in bone disease. Researchers and students in the fields of human genetics, human physiology, developmental biology and biomedical engineering, as well as professionals and scientists in Orthopedics, will particularly find this book helpful.
Noncommutative Geometry and Particle Physics (Mathematical Physics Studies)
by Walter D. van SuijlekomThis book provides an introduction to noncommutative geometry and presents a number of its recent applications to particle physics. In the first part, we introduce the main concepts and techniques by studying finite noncommutative spaces, providing a “light” approach to noncommutative geometry. We then proceed with the general framework by defining and analyzing noncommutative spin manifolds and deriving some main results on them, such as the local index formula. In the second part, we show how noncommutative spin manifolds naturally give rise to gauge theories, applying this principle to specific examples. We subsequently geometrically derive abelian and non-abelian Yang-Mills gauge theories, and eventually the full Standard Model of particle physics, and conclude by explaining how noncommutative geometry might indicate how to proceed beyond the Standard Model. The second edition of the book contains numerous additional sections and updates. More examples of noncommutative manifolds have been added to the first part to better illustrate the concept of a noncommutative spin manifold and to showcase some of the key results in the field, such as the local index formula. The second part now includes the complete noncommutative geometric description of particle physics models beyond the Standard Model. This addition is particularly significant given the developments and discoveries at the Large Hadron Collider at CERN over the last few years. Additionally, a chapter on the recent progress in formulating noncommutative quantum theory has been included. The book is intended for graduate students in mathematics/theoretical physics who are new to the field of noncommutative geometry, as well as for researchers in mathematics/theoretical physics with an interest in the physical applications of noncommutative geometry.
Noncontact Atomic Force Microscopy
by Ernst Meyer Seizo Morita Franz J. Giessibl Roland WiesendangerThis book presents the latest developments in noncontact atomic force microscopy. It deals with the following outstanding functions and applications that have been obtained with atomic resolution after the publication of volume 2: (1) Pauli repulsive force imaging of molecular structure, (2) Applications of force spectroscopy and force mapping with atomic resolution, (3) Applications of tuning forks, (4) Applications of atomic/molecular manipulation, (5) Applications of magnetic exchange force microscopy, (6) Applications of atomic and molecular imaging in liquids, (7) Applications of combined AFM/STM with atomic resolution, and (8) New technologies in dynamic force microscopy. These results and technologies are now expanding the capacity of the NC-AFM with imaging functions on an atomic scale toward making them characterization and manipulation tools of individual atoms/molecules and nanostructures, with outstanding capability at the level of molecular, atomic, and subatomic resolution. Since the publication of vol. 2 of the book Noncontact Atomic Force Microscopy in 2009 the noncontact atomic force microscope, which can image even insulators with atomic resolution, has achieved remarkable progress. The NC-AFM is now becoming crucial for nanoscience and nanotechnology.
Noncovalent Forces
by Steve ScheinerComputational methods, and in particular quantum chemistry, have taken the lead in our growing understanding of noncovalent forces, as well as in their categorization. This volume describes the current state of the art in terms of what we now know, and the current questions requiring answers in the future. Topics range from very strong (ionic) to very weak (CH--π) interactions. In the intermediate regime, forces to be considered are H-bonds, particularly CH--O and OH--metal, halogen, chalcogen, pnicogen and tetrel bonds, aromatic stacking, dihydrogen bonds, and those involving radicals. Applications include drug development and predictions of crystal structure.
Noncovalent Functionalization of Carbon Nanotubes
by Claudia BackesIn this thesis, Claudia Backes guides the reader through her multidisciplinary research into the non-covalent functionalization of carbon nanotubes in water. Although one of the most remarkable materials of the 21st century, carbon nanotubes often have limited application because of their intrinsically low solubility and polydispersity. The author shows that rational surfactant design is a powerful tool for chemists because it can unmask the key to solubilization and allow us to tailor nanotube surface and optical properties in a fully reversible fashion. Aspects of organic, physical and analytical chemistry, as well as colloidal sciences are covered in this outstanding work which brings us one step closer to exploiting this super-material to its full potential.
Nondestructive Assay of Nuclear Materials for Safeguards and Security
by Martyn T. Swinhoe William H. Geist Peter A. SantiThis open access book describes the nondestructive assay techniques that are used for the measurement of nuclear material (primarily uranium and plutonium) for nuclear material accountancy purposes. It is a substantial revision to the so-called PANDA manual that has been a standard reference since its publication in 1991. The book covers the origin and interactions of gamma rays and neutrons as they affect nuclear measurements and also describes the theory and practice of calorimetry. The book gives a description of many instruments based on these techniques that are applied in the field. Although the basic physics has not changed since PANDA was first published, the last thirty years have seen many advances in analysis methods, instrumentation, and applications. The basic descriptions of the origin and interactions of radiation have been updated and include newer references. There have been extensive revisions of the description of gamma detection methods, attenuation correction procedures, and analysis methods, including for the measurement of uranium enrichment and the determination of plutonium isotopic composition. Extensive revisions and additions have also been made to the description of neutron detectors and to the explanation of neutron coincidence techniques. The chapter on neutron multiplicity techniques is a new addition to this edition. The applications of gamma and neutron techniques have been completely overhauled to remove obsolete systems and to include many current applications. The values of, and references to, nuclear data have been updated. This updated edition is an essential reference for academic researchers and practitioners in the field. This is an open access book.
Nondestructive Biomarkers in Vertebrates
by Cristina Fossi Claudio LeonzioNondestructive Biomarkers in Vertebrates presents an innovative approach for hazard assessment in vertebrates based on nondestructive rather than destructive methods. The book reviews the state of the art and defines the development and validation procedure of this new strategy. Biological materials, such as blood samples, epithelial tissue, eggs, feathers, and feces that can be obtained without stress or damage to the animal are suggested. Certain traditional studies (blood esterases, blood chemistry, mixed function oxidases, porphyrins, DNA damage, and cytological changes) can be performed on these specimens, along with new tests requiring only very small samples. This approach is developed to benefit protected, threatened species whose existence cannot be further jeopardized by the use of destructive methods. This volume will be particularly useful to ecotoxicologists, wildlife protection personnel, environmental consultants, and conservationist organizations.
Nondestructive Evaluation of Food Quality
by Shyam N. JhaNumerous works on non-destructive testing of food quality have been reported in the literature. Techniques such as Near InfraRed (NIR) spectroscopy, color and visual spectroscopy, electronic nose and tongue, computer vision (image analysis), ultrasound, x-ray, CT and magnetic resonance imaging are some of the most applied for that purpose and are described in this book. Aspects such as theory/basics of the techniques, practical applications (sampling, experimentation, data analysis) for evaluation of quality attributes of food and some recent works reported in literature are presented and discussed. This book is particularly interesting for new researchers in food quality and serves as an updated state-of-the-art report for those already familiar with the field.
Nondestructive Quality Assessment Techniques for Fresh Fruits and Vegetables
by Mohammad Shafiur Rahman Pankaj B. PathareThis book describes the various techniques for nondestructive quality assessment of fruits and vegetables. It covers the methods, measurements, operation principles, procedures, data analysis, and applications for implementing these techniques.The book presents the details of nondestructive approaches focusing on the present-day trends and existing future opportunities in the fresh food supply chain. First, it overviews different nondestructive techniques in food quality detection. Then it presents nondestructive methods: monochrome computer vision, imaging techniques, biospeckle laser technique, Fourier Transform Infrared (FTIR) Spectroscopy, hyperspectral imaging, Raman spectroscopy, near infrared (NIR) spectroscopy, X-ray computed tomography, ultrasound, acoustic emission, chemometrics, electronic nose and tongue. Selected applications of each method are also introduced. As a result, readers gain a better understanding of how to use nondestructive methods and technologies to detect the quality of fresh fruits and vegetables.With a wide range of interesting topics, the book will benefit readers including postharvest & food scientists/technologists, industry personnel and researchers involved in fresh produce quality detection. The book can also serve as a readily accessible reference material for postgraduate students.
Nondestructive Testing and Evaluation of Fiber-Reinforced Composite Structures
by Shuncong Zhong Walter NsengiyumvaThis book presents a detailed description of the most common nondestructive testing(NDT) techniques used for the testing and evaluation fiber-reinforced composite structures, during manufacturing and/or in service stages. In order to facilitate the understanding and the utility of the different NDT techniques presented, the book first provides some information regarding the defects and material degradation mechanisms observed in fiber-reinforced composite structures as well as their general description and most probable causes. It is written based on the extensive scientific research and engineering backgrounds of the authors in the NDT and structural health monitoring (SHM) of structural systems from various areas including electrical, mechanical, materials, civil and biomedical engineering. Pursuing a rigorous approach, the book establishes a fundamental framework for the NDT of fiber-reinforced composite structures, while emphasizing on the importance of technique’s spatial resolution, integrated systems analysis and the significance of the influence stemming from the applicability of the NDT and the physical parameters of the test structures in the selection and utilization of adequate NDT techniques.The book is intended for students who are interested in the NDT of fiber-reinforced composite structures, researchers investigating the applicability of different NDT techniques to the inspections of structural systems, and NDT researchers and engineers working on the optimization of NDT systems for specific applications involving the use of fiber-reinforced composite structures.
Nondestructive Testing of Materials and Structures
by Mehmet Ali Taşdemir Oral Büyüköztürk Oğuz Güneş Yılmaz AkkayaCondition assessment and characterization of materials and structures by means of nondestructive testing (NDT) methods is a priority need around the world to meet the challenges associated with the durability, maintenance, rehabilitation, retrofitting, renewal and health monitoring of new and existing infrastructures including historic monuments. Numerous NDT methods that make use of certain components of the electromagnetic and acoustic spectrum are currently in use to this effect with various levels of success and there is an intensive worldwide research effort aimed at improving the existing methods and developing new ones. The knowledge and information compiled in this book captures the current state of the art in NDT methods and their application to civil and other engineering materials and structures. Critical reviews and advanced interdisciplinary discussions by world-renowned researchers point to the capabilities and limitations of the currently used NDT methods and shed light on current and future research directions to overcome the challenges in their development and practical use. In this respect, the contents of this book will equally benefit practicing engineers and researchers who take part in characterization, assessment and health monitoring of materials and structures.
Nonequilibrium Atmospheric Pressure Plasma Jets: Fundamentals, Diagnostics, and Medical Applications
by XinPei Lu Stephan Reuter Mounir Laroussi DaWei LiuNonequilibrium atmospheric pressure plasma jets (N-APPJs) generate plasma in open space rather than in a confined chamber and can be utilized for applications in medicine. This book provides a complete introduction to this fast-emerging field, from the fundamental physics, to experimental approaches, to plasma and reactive species diagnostics. It provides an overview of the development of a wide range of plasma jet devices and their fundamental mechanisms. The book concludes with a discussion of the exciting application of plasmas for cancer treatment. The book provides details on experimental methods including expert tips and caveats. covers novel devices driven by various power sources and the impact of operating conditions on concentrations and fluxes of the reactive species. discusses the latest advances including theory, modeling, and simulation approaches. gives an introduction, overview and details on state of the art diagnostics of small scale high gradient atmospheric pressure plasmas. covers the use of N-APPJs for cancer applications, including discussion of destruction of cancer cells, mechanisms of action, and selectivity studies. XinPei Lu is a Chair Professor in the School of Electrical and Electronic Engineering at Huazhong University of Science and Technology. Stephan Reuter is currently Visiting Professor at Université Paris-Saclay. In a recent Alexander von Humboldt research fellowship at Princeton University, he performed ultrafast laser spectroscopy on cold plasmas. Mounir Laroussi is Professor of Electrical and Computer Engineering and director of the Plasma Engineering and Medicine Institute at Old Dominion University. He is a Fellow of IEEE and recipient of an IEEE Merit Award. DaWei Liu is Professor in the School of Electrical and Electronic Engineering at Huazhong University of Science and Technology.
Nonequilibrium Dynamics of Collective Excitations in Quantum Materials (Springer Theses)
by Edoardo BaldiniThis book studies the dynamics of fundamental collective excitations in quantum materials, focusing on the use of state-of-the-art ultrafast broadband optical spectroscopy. Collective behaviour in solids lies at the origin of several cooperative phenomena that can lead to profound transformations, instabilities and phase transitions. Revealing the dynamics of collective excitations is a topic of pivotal importance in contemporary condensed matter physics, as it provides information on the strength and spatial distribution of interactions and correlation. The experimental framework explored in this book relies on setting a material out-of-equilibrium by an ultrashort laser pulse and monitoring the photo-induced changes in its optical properties over a broad spectral region in the visible or deep-ultraviolet. Collective excitations (e.g. plasmons, excitons, phonons…) emerge either in the frequency domain as spectral features across the probed range, or in the time domain as coherent modes triggered by the pump pulse. Mapping the temporal evolution of these collective excitations provides access to the hierarchy of low-energy phenomena occurring in the solid during its path towards thermodynamic equilibrium. This methodology is used to investigate a number of strongly interacting and correlated materials with an increasing degree of internal complexity beyond conventional band theory.
Nonequilibrium Green's Functions Approach to Inhomogeneous Systems
by Karsten Balzer Michael BonitzThis book offers a self-contained introduction to non-equilibrium quantum particle dynamics for inhomogeneous systems, including a survey of recent breakthroughs pioneered by the authors and others. The approach is based on real-time Green's functions.
Nonequilibrium Many-Body Theory of Quantum Systems
by Gianluca Stefanucci Robert Van LeeuwenThe Green's function method is one of the most powerful and versatile formalisms in physics, and its nonequilibrium version has proved invaluable in many research fields. This book provides a unique, self-contained introduction to nonequilibrium many-body theory. Starting with basic quantum mechanics, the authors introduce the equilibrium and nonequilibrium Green's function formalisms within a unified framework called the contour formalism. The physical content of the contour Green's functions and the diagrammatic expansions are explained with a focus on the time-dependent aspect. Every result is derived step-by-step, critically discussed and then applied to different physical systems, ranging from molecules and nanostructures to metals and insulators. With an abundance of illustrative examples, this accessible book is ideal for graduate students and researchers who are interested in excited state properties of matter and nonequilibrium physics.
Nonequilibrium Molecular Dynamics
by Billy D. Todd Peter J. DaivisWritten by two specialists with over twenty-five years of experience in the field, this valuable text presents a wide range of topics within the growing field of nonequilibrium molecular dynamics (NEMD). It introduces theories which are fundamental to the field - namely, nonequilibrium statistical mechanics and nonequilibrium thermodynamics - and provides state-of-the-art algorithms and advice for designing reliable NEMD code, as well as examining applications for both atomic and molecular fluids. It discusses homogenous and inhomogenous flows and pays considerable attention to highly confined fluids, such as nanofluidics. In addition to statistical mechanics and thermodynamics, the book covers the themes of temperature and thermodynamic fluxes and their computation, the theory and algorithms for homogenous shear and elongational flows, response theory and its applications, heat and mass transport algorithms, applications in molecular rheology, highly confined fluids (nanofluidics), the phenomenon of slip and how to compute it from basic microscopic principles, and generalized hydrodynamics.
Nonequilibrium Phase Transitions in Driven Vortex Matter: The Reversible-Irreversible Transition, Dynamical Ordering, and Kibble-Zurek Mechanism (Springer Theses)
by Shun MaegochiThis book presents experimental studies of nonequilibrium phase transitions induced by ac and dc forces in collectively interacting systems—a superconducting vortex system with random pinning. It first shows that a phase transition from reversible to irreversible flow occurs by increasing vortex density as well as amplitude of ac shear, which is indicative of the universality of the reversible-irreversible transition. Two distinct flow regimes are also found in the reversible phase. Next, the book presents new methods for dc driven experiments—transverse mode-locking and transverse current-voltage measurements—and provides convincing evidence of the second-order dynamical transition from disordered plastic to anisotropically ordered smectic flow. Lastly it reports on the first experimental demonstration of the Kibble-Zurek mechanism for the nonequilibrium phase transition.The experimental results indicate that both the reversible-irreversible transition and the dynamical ordering transition belong to the directed percolation universality class which is one of the fundamental classes of nonequilibrium phase transitions. Hence, the findings will be generalized to other nonequilibrium systems and stimulate research on nonequilibrium physics.
Nonequilibrium Processes in Catalysis
by Oleg V. KrylovNonequilibrium Processes in Catalysis presents modern ideas and experimental data (e.g., molecular beams, laser technique) on adsorption and catalysis, the mechanism of energy exchange in the processes of particles interaction with a surface, and the lifetimes of excited particles on a surface. Previously unpublished theoretical information regarding the principle of chemoenergetical stimulation accounting for the acceleration of one reaction at the expense of reactant excitation in another is provided, and new ideas about nonequilibrium surface diffusion are explored. Examples of the formation of nonequilibrium dissipative structures in catalysis are presented, including auto-oscillations, auto-waves, multiplicity of kinetic regimes, nonequilibrium phase transition, and decelerated electron exchange between solid and adsorbed species. The book also describes new experimental methods for studying nonequilibrium and quick processes in catalysis. Nonequilibrium Processes in Catalysis will benefit physicists involved with surface science, chemists involved with adsorption and catalysis, engineers, vacuum scientists, physical chemists, materials chemists, students, and others interested in these processes.
Nonequilibrium Statistical Mechanics of Heterogeneous Fluid Systems
by Andrei G. BashkirovThere is a wide variety of heterogeneous fluid systems that possess interphase surfaces. This monograph is devoted to pioneering studies in nonequilibrium statistical mechanics of such systems. Starting from the Liouville equation, the equations of surface hydrodynamics are derived with allowance for discontinuities of thermodynamic parameters of interphase boundaries. Brownian motion of a large solid particle in a fluid and nucleation are treated as results of fluctuations of flows across particle surfaces. With the use of the Gibbs method, a shock wave in a gas is considered as a sort of an interphase surface, and the surface tension of a shock front is introduced for the first time.
Nonequilibrium Statistical Mechanics: An Introduction with Applications
by Biman BagchiNonequilibrium statistical mechanics (NESM), practically synonymous with time-dependent statistical mechanics (TDSM), is a beautiful and profound subject, vast in scope, diverse in applications, and indispensable in understanding the changing natural phenomena we encounter in the physical, chemical and biological world. Although time dependent phenomena have been studied from antiquity, the modern subject, the nonequilibrium statistical mechanics, has its genesis in Boltzmann’s 1872 classic paper that aimed at extending Maxwell’s kinetic theory of gases by including intermolecular interactions. Subsequent development of the subject drew upon the seminal work of Einstein and Langevin on Brownian motion, Rayleigh and Stokes on hydrodynamics, and on the works of Onsager, Prigogine, Kramers, Kubo, Mori, and Zwanzig. One major goal of this book is to develop and present NESM in an organized fashion so that students can appreciate and understand the flow of the subject from postulates to practical uses. This book takes the students on a journey from fundamentals to applications, mostly using simple mathematics, and fundamental concepts. With the advent of computers and computational packages and techniques, a deep intuitive understanding can allow the students to tackle fairly complex problems, like proteins in lipid membranes or solvation of ions in electrolytes used in batteries. The subject is still evolving rapidly, with forays into complex biological events, and materials science. Nonequilibrium Statistical Mechanics: An Introduction with Applications is, thus, an introductory text that aims to provide students with a background and skill essential to study and understand time-dependent (relaxation) phenomena. It will allow students to calculate transport properties like diffusion and conductivity. The book also teaches the methods to calculate reaction rate on a multi-dimensional energy surface, in another such application. For a beginner in the field, especially for one with an aim to study chemistry and biology, and also physics, one major difficulty faced is a lack of organization of the available study material. Since NESM is a vast subject with many different theoretical tools, the above poses a problem. This book lays the foundations towards understanding time- dependent phenomena in a simple and systematic fashion. It is accessible to students and researchers who have basic training in physics and mathematics. The book can be used to teach advanced undergraduates. Some involved topics, like the projection operator technique and mode coupling theory, are more suitable for Ph.D. level.
Nonequilibrium Statistical Physics: A Modern Perspective
by Roberto Livi Paolo PolitiStatistical mechanics has been proven to be successful at describing physical systems at thermodynamic equilibrium. Since most natural phenomena occur in nonequilibrium conditions, the present challenge is to find suitable physical approaches for such conditions: this book provides a pedagogical pathway that explores various perspectives. The use of clear language, and explanatory figures and diagrams to describe models, simulations and experimental findings makes the book a valuable resource for undergraduate and graduate students, and also for lecturers organizing teaching at varying levels of experience in the field. Written in three parts, it covers basic and traditional concepts of nonequilibrium physics, modern aspects concerning nonequilibrium phase transitions, and application-orientated topics from a modern perspective. A broad range of topics is covered, including Langevin equations, Levy processes, directed percolation, kinetic roughening and pattern formation.
Nonhuman DNA Typing: Theory and Casework Applications (International Forensic Science and Investigation)
by Heather Miller CoyleThe association of a suspect with the victim or crime scene through DNA evidence is one of the most powerful statements of complicity in a crime imaginable. No category of evidence has ever had the complete capacity to convict or exonerate an accused so absolutely in the eyes of the public. With the discriminatory powers of DNA and the variety of D
Nonhuman Humanitarians: Animal Interventions in Global Politics
by Benjamin MeichesExamining the appearance of nonhuman animals laboring alongside humans in humanitarian operations Both critical and mainstream scholarly work on humanitarianism have largely been framed from anthropocentric perspectives highlighting humanity as the rationale for providing care to others. In Nonhuman Humanitarians, Benjamin Meiches explores the role of animals laboring alongside humans in humanitarian operations, generating new ethical possibilities of care in humanitarian practice.Nonhuman Humanitarians examines how these animals not only improve specific practices of humanitarian aid but have started to transform the basic tenets of humanitarianism. Analyzing case studies of mine-clearance dogs, milk-producing cows and goats, and disease-identifying rats, Nonhuman Humanitarians ultimately argues that nonhuman animal contributions problematize foundational assumptions about the emotional and rational capacities of humanitarian actors as well as the ethical focus on human suffering that defines humanitarianism.Meiches reveals that by integrating nonhuman animals into humanitarian practice, several humanitarian organizations have effectively demonstrated that care, compassion, and creativity are creaturely rather than human and that responses to suffering and injustice do not—and cannot—stop at the boundaries of the human.
Nonhuman Primate Models For Human Diseases
by W. Richard DukelowWhile research has enabled us to better understand the nonhuman primates, they have repaid that by repaid that by providing medical scientists with important tools for the study of human biomedical problems. This book is about those research tools. The book was designed by identifying areas of human medical research that are under intensive research study today. Authors were then selected based on their expertise at using nonhuman primates as models for the human condition. Each was asked to use as comparative an approach as models for the human condition. Each was asked to use a comparative an approach as possible, to provide the reader with knowledge relating to the usefulness of various nonhuman primate species to each specific research area.
Noninvasive Instrumentation and Measurement in Medical Diagnosis
by Robert B. NorthropNoninvasive medical diagnosis (NIMD) is as old as medical practice itself. From the earliest healers' observations of odors, skin color, and breath sounds to today's wealth of technologies, the basics remain the same and keep the role of NIMD essential to effective medical care. Noninvasive Instrumentation and Measurement in Medical Diagnos