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Positron Emission Tomography: Methods and Protocols (Methods in Molecular Biology #2729)
by Timothy H. Witney Adam J. ShuhendlerThis detailed volume explores key concepts and experimental design related to Positron Emission Tomography (PET) imaging that have revolutionized our understanding of human biology. The first part focuses on recent advances in radiotracer probe development to enable the detection of materials, from large macromolecules to complicated drug-like structures. The next section describes how key physiological and pathophysiological processes can be interrogated and quantifiably measured with this imaging technique. Finally, chapters examine important technological developments in the field that are revolutionizing the way these innovative PET probes are utilized in the clinic. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Positron Emission Tomography: Methods and Protocols serves as an ideal guide for researchers looking to use imaging to revolutionize the way we diagnose and treat disease.
Positron Profilometry: Probing Material Depths for Enhanced Understanding (SpringerBriefs in Materials)
by Jerzy DryzekThis book provides a comprehensive overview of positron profilometry, specifically focusing on the analysis of defect depth distribution in materials. Positron profilometry plays a crucial role in understanding and characterizing defects in a wide range of materials, including metals, semiconductors, polymers, and ceramics. By analyzing the depth distribution of defects, researchers can gain insights into various material properties, such as crystal structure, defect density, and diffusion behavior. The author's extensive research spanning a period of two decades has primarily centered on subsurface zones. These regions, located beneath the surface and subjected to various surface processes, play a crucial role in generating defect distributions. Three experimental techniques and their data analysis are described in detail: a variable-energy positron beam (VEP) called sometimes a slow positron beam, a technique called implantation profile depth scanning (DSIP), and a sequential etching (SET) technique. The usability of these techniques is illustrated by many examples of measurements by the author and others.
The Possibility of Life: Science, Imagination, and Our Quest for Kinship in the Cosmos
by Jaime Green*An NPR Science Friday Book Club Pick**A "Next Big Idea Book Club" Must Read**A Gizmodo New Release Pick for April**A BookRiot Science Book to Add to Your TBR**A Wired Book to Read for Spring*"A dazzling feat of imagination and synthesis."—Ed Yong, Pulitzer Prize winner and author of An Immense WorldA spellbinding exploration of alien life and the cosmos, examining how the possibility of life on other planets shapes our understanding of humanityOne of the most powerful questions humans ask about the cosmos is: Are we alone? While the science behind this inquiry is fascinating, it doesn&’t exist in a vacuum. It is a reflection of our values, our fears, and most importantly, our enduring sense of hope. In The Possibility of Life, acclaimed science journalist Jaime Green traces the history of our understanding, from the days of Galileo and Copernicus to our contemporary quest for exoplanets. Along the way, she interweaves insights from science fiction writers who construct worlds that in turn inspire scientists. Incorporating expert interviews, cutting-edge astronomy research, philosophical inquiry, and pop culture touchstones ranging from A Wrinkle in Time to Star Trek to Arrival, The Possibility of Life explores our evolving conception of the cosmos to ask an even deeper question: What does it mean to be human?
Possibility Theory for the Design of Information Fusion Systems (Information Fusion and Data Science)
by Basel Solaiman Éloi BosséThis practical guidebook describes the basic concepts, the mathematical developments, and the engineering methodologies for exploiting possibility theory for the computer-based design of an information fusion system where the goal is decision support for industries in smart ICT (information and communications technologies). This exploitation of possibility theory improves upon probability theory, complements Dempster-Shafer theory, and fills an important gap in this era of Big Data and Internet of Things.The book discusses fundamental possibilistic concepts: distribution, necessity measure, possibility measure, joint distribution, conditioning, distances, similarity measures, possibilistic decisions, fuzzy sets, fuzzy measures and integrals, and finally, the interrelated theories of uncertainty..uncertainty. These topics form an essential tour of the mathematical tools needed for the latter chapters of the book. These chapters present applications related to decision-making and pattern recognition schemes, and finally, a concluding chapter on the use of possibility theory in the overall challenging design of an information fusion system. This book will appeal to researchers and professionals in the field of information fusion and analytics, information and knowledge processing, smart ICT, and decision support systems.
Possible Health Effects of Exposure to Residential Electric And Magnetic Fields
by Committee on the Possible Effects of Electromagnetic Fields on Biologic SystemsCan the electric and magnetic fields (EMF) to which people are routinely exposed cause health effects? This volume assesses the data and draws conclusions about the consequences of human exposure to EMF. The committee examines what is known about three kinds of health effects associated with EMF: cancer, primarily childhood leukemia; reproduction and development; and neurobiological effects. This book provides a detailed discussion of hazard identification, dose-response assessment, exposure assessment, and risk characterization for each.Possible Health Effects of Exposure to Residential Electric and Magnetic Fields also discusses the tools available to measure exposure, common types of exposures, and what is known about the effects of exposure. The committee looks at correlations between EMF exposure and carcinogenesis, mutagenesis, neurobehavioral effects, reproductive and developmental effects, effects on melatonin and other neurochemicals, and effects on bone healing and stimulated cell growth.
Possible Knowledge: The Literary Forms of Early Modern Science
by Debapriya SarkarThe Renaissance, scholars have long argued, was a period beset by the loss of philosophical certainty. In Possible Knowledge, Debapriya Sarkar argues for the pivotal role of literature—what early moderns termed poesie—in the dynamic intellectual culture of this era of profound incertitude. Revealing how problems of epistemology are inextricable from questions of literary form, Sarkar offers a defense of poiesis, or literary making, as a vital philosophical endeavor.Working across a range of genres, Sarkar theorizes “possible knowledge” as an intellectual paradigm crafted in and through literary form. Sixteenth- and seventeenth-century writers such as Spenser, Bacon, Shakespeare, Cavendish, and Milton marshalled the capacious concept of the “possible,” defined by Philip Sidney as what “may be and should be,” to construct new theories of physical and metaphysical reality. These early modern thinkers mobilized the imaginative habits of thought constitutive to major genres of literary writing—including epic, tragedy, romance, lyric, and utopia—in order to produce knowledge divorced from historical truth and empirical fact by envisioning states of being untethered from “nature” or reality.Approaching imaginative modes such as hypothesis, conjecture, prediction, and counterfactuals as instruments of possible knowledge, Sarkar exposes how the speculative allure of the “possible” lurks within scientific experiment, induction, and theories of probability. In showing how early modern literary writing sought to grapple with the challenge of forging knowledge in an uncertain, perhaps even incomprehensible world, Possible Knowledge also highlights its most audacious intellectual ambition: its claim that while natural philosophy, or what we today term science, might explain the physical world, literature could remake reality. Enacting a history of ideas that centers literary studies, Possible Knowledge suggests that what we have termed a history of science might ultimately be a history of the imagination.
Possible Worlds
by J.B.S. HaldaneHaldane advanced genetics, population biology and evolutionary theory. This volume emphasizes important developments in natural sciences in the early-20th century. It describes Haldane's views on society, art, religion and economy as seen through the eyes of a politically alert major scientist.
Post 2030-Agenda and the Role of Space: The UN 2030 Goals and Their Further Evolution Beyond 2030 for Sustainable Development (Studies in Space Policy #17)
by Annette FroehlichThis book provides a deep insight to which extent further improvement should be envisaged to ensure and improve the sustainable development beyond 2030 (the Sustainable Development Goals is a set of 17 global goals with 169 associated targets which the state community adopted in 2015). As the world, its environment, economy and society is getting more and more technical advanced, it is of high interest to analyze how space and its various applications can support this development. Once the Goals of the “2030 Agenda for Sustainable Development” will be achieved new challenges are waiting. The analysis takes into account a proactive use of artificial intelligence for the development based on space infrastructure. Another important aspect revolves around the economic development which asks for further analysis of the cryptocurrencies relationship with space applications and how to use space based cryptocurrencies for development. Environment-wise the challenges for a sustainable development on Earth i.e. water supply, but also in outer space are requested ensuring a sustainable exploration and exploitation of space and its orbital resources. The book also highlights possible contributions of the post-2030 space industry to global economic development based on satellite technology and the enlargement of the scope of application of satellite data in administration and Justice to ensure development of effective, accountable and transparent institutions at all levels to promote growth, stability and security and peace on global level.
Post-Cold War Conflict Deterrence
by Naval Studies BoardDeterrence as a strategic concept evolved during the Cold War. During that period, deterrence strategy was aimed mainly at preventing aggression against the United States and its close allies by the hostile Communist power centers--the Union of Soviet Socialist Republics (USSR) and its allies, Communist China and North Korea. In particular, the strategy was devised to prevent aggression involving nuclear attack by the USSR or China. Since the end of the Cold War, the risk of war among the major powers has subsided to the lowest point in modern history. Still, the changing nature of the threats to American and allied security interests has stimulated a considerable broadening of the deterrence concept.Post-Cold War Conflict Deterrence examines the meaning of deterrence in this new environment and identifies key elements of a post-Cold War deterrence strategy and the critical issues in devising such a strategy. It further examines the significance of these findings for the U.S. Navy and Marine Corps. Quantitative and qualitative measures to support judgments about the potential success or failure of deterrence are identified. Such measures will bear on the suitability of the naval forces to meet the deterrence objectives. The capabilities of U.S. naval forces that especially bear on the deterrence objectives also are examined. Finally, the book examines the utility of models, games, and simulations as decision aids in improving the naval forces' understanding of situations in which deterrence must be used and in improving the potential success of deterrence actions.
Post-combustion CO2 Capture Technology: By Using the Amine Based Solvents (SpringerBriefs in Petroleum Geoscience & Engineering)
by Helei Liu Raphael Idem Paitoon TontiwachwuthikulThis book presents a comprehensive review of the latest information on all aspects of the post-combustion carbon capture process. It provides designers and operators of amine solvent-based CO2 capture plants with an in-depth understanding of the most up-to-date fundamental chemistry and physics of the CO2 absorption technologies using amine-based reactive solvents. Topics covered include the physical properties, chemical analysis, reaction kinetics, CO2 solubility, and innovative configurations of absorption and stripping columns as well as information on technology applications. This book also examines the post-build operational issues of corrosion prevention and control, solvent management, solvent stability, solvent recycling and reclaiming, intelligent monitoring and plant control including process automation. In addition, the authors discuss the recent insights into the theoretical basis of plant operation in terms of thermodynamics, transport phenomena, chemical reaction kinetics/engineering, interfacial phenomena, and materials. The insights provided help engineers, scientists, and decision makers working in academia, industry and government gain a better understanding of post-combustion carbon capture technologies.
Post-conflict Security, Peace and Development: Perspectives From Africa, Latin America, Europe And New Zealand (Springerbriefs In Environment, Security, Development And Peace Ser. #13)
by Christine Atieno Colin RobinsonThis book examines links between post-conflict security, peace and development in Africa, Latin America, Europe and New Zealand. Young peace researchers from the Global South (Uganda, Ivory Coast, Kenya, Brazil, Colombia) as well as from Italy and New Zealand address in case studies traumas in Northern Uganda, demobilisation and reintegration of ex-combatants in the Ivory Coast, economic and financial management of terrorism in Kenya, organised crime in Brazil, mental health issues in Colombia, macro realism in Europe and global defence reforms within the military apparatus since 1990. The book reviews linkages between regional stability, development and peace in post-conflict societies while adding on to the post 2015 international agenda and discusses linkages between peace, security and development.
Post-Disaster Governance in Southeast Asia: Response, Recovery, and Resilient Societies (Disaster Risk Reduction)
by Andri N. R. Mardiah Robert B. Olshansky Mizan B. F. BisriThis book aims to provide insight into how Southeast Asian countries have responded to disasters, recovered, and rebuilt. It investigates emergency response and disaster recovery cases at national levels and from regional perspectives. Recovery from great disasters poses great challenges to affected countries in terms of organization, financing, and opportunities for post-disaster betterment. Importantly, disasters are critical moments in which to achieve disaster risk reduction, especially in the context of climate change and Sustainable Development Goals. Insights from these cases can help other countries better prepare for response and recovery before the next disaster strikes. While the experiences of disaster risk reduction and climate change implementation in Southeast Asian countries have been well documented, tacit knowledge from emergency response and recovery from these countries has not been transformed into explicit knowledge. There are only a few books that integrate information and lessons from post-disaster governance in Southeast Asia as a region, and because of the importance of providing real and recent situations, this book will interest many policymakers, practitioners, and academics. The information presented here will lead to a better understanding of how to plan for future disasters and improve governance to ensure effective emergency response as well as encouraging a build back better and safer towards a more resilient and sustained recovery.
Post-Disaster Reconstruction and Change: Communities' Perspectives
by Jennifer E. Duyne Barenstein Esther LeemannSuccessful recovery following a disaster depends upon transcending the disciplinary divides of architecture, engineering, and planning and emphasizing the importance of community perspectives in the post-disaster reconstruction process. Effective results in community recovery mandate that we holistically examine the complex interrelationship betwee
Post-Dryout Heat Transfer (Multiphase Science And Technology Ser.)
by G.F. HewittThe study of post-dryout heat transfer has generated great interest because of its importance in determining maximum clad temperature in nuclear reactor loss-of-coolant accidents (LOCAs). An associated phenomenon, the deterioration of heat transfer in boiling, is significant to other industrial sectors. This book provides comprehensive coverage of post-dryout heat transfer, discussing such essential topics as post-dryout heat transfer in dispersed flow, interpretation and use of transient data in surface rewetting by reinstatement of flow or by reducing heat flux, rod bundles, two-phase flow occurrences in the post-dryout region, various methods for predicting ""inverted annular flow,"" and new experiments for measuring thermodynamic nonequilibrium with probes in the channel. The book also presents a basis for independent safety assessment of nuclear reactors and chemical plant systems where post-dryout heat transfer may occur. Post-Dryout Heat Transfer will be a useful reference for researchers and professionals in the nuclear and chemical production industries.
Post-Fire Management and Restoration of Southern European Forests
by Piermaria Corona Francisco Moreira Margarita Arianoutsou Jorge De las HerasIn spite of all the efforts made in fire prevention and suppression, every year about 45 000 forest fires occur in Europe, burning ca. 0.5 million hectares of forests and other rural lands. The management of these burned forests has been given much less attention than fire prevention or fire suppression issues, but the post-fire management of burned areas raises strong concerns (economic and social impacts, soil erosion and water quality, biodiversity loss, forest restoration). Although there are a few publications which address post-fire management, the focus of these has been either on general approaches to restoration or specific topics such as preventing post-fire soil erosion. This book is about the post-fire management of fire-prone forest types in southern Europe. It provides the first comprehensive overview of the topic, ranging from stand-level to landscape-level management, and from emergency actions to long-term restoration approaches.
Post-Genome Biology of Primates
by Hirohisa Hirai Hiroo Imai Yasuhiro GoIn 2001, first reports of the human draft genome were published. Since then, genomes of many other organisms have been sequenced, including several primate species: the chimpanzee, rhesus macaque, gorilla, orangutan, gibbon, baboon, marmoset, tarsier, galago, lemur, and more recently Neanderthals. In a new era of "post-genome biology", scientists now have the vast amount of information revealed by genome research to confront one of the most challenging, fundamental questions in primatology and anthropology: What makes us human? This volume comprises a collection of articles on a variety of topics relevant to primate genomes, including evolution, human origins, genome structure, chromosome genomics, and bioinformatics. The book covers the cutting-edge research in molecular primatology and provides great insights into the functional diversity of primates. This valuable collection will benefit researchers and students, including primatologists, anthropologists, molecular biologists, evolutionary biologists, and animal behaviorists.
Post-genomic Approaches in Cancer and Nano Medicine (River Publishers Series In Research And Business Chronicles: Biotechnology And Medicine Ser.)
by Kishore R Sakharkar Meena K Sakharkar Ramesh ChandraUnderstanding the molecular mechanisms of cancer is the key for transforming cancer medicine. A substantial proportion of human genes show alternative splicing and mis-regulation of Pre-mRNA splicing is seen in several cancers.This book further investigates these matters. The first few chapters provide an update on the role of genomics in understanding alternative splicing, and targets in cancer pathogenesis. Advances and prospects in applications of nanotechnology for cancer prevention, detection and treatment are a promising field of research. The subsequent chapters provide insights on how nanotechnology-based therapeutics are moving towards revolutionizing cancer and infectious disease treatment by minimizing toxicity and facilitating targeted delivery of drugs. Technical topics discussed in the book include: • Alternative splicing and cancer• Cancer imaging• Nanomaterials in infectious diseases• Nanomedicine in oxidative stress and cancer• Nanoparticle based drug delivery systems
Post-growth Politics: A Critical Theoretical and Policy Framework for Decarbonisation (Green Energy and Technology)
by Peter FergusonThis book uses a critical political economy approach to develop an historically and politically grounded set of strategies for states to move toward a post-growth, decarbonised global economy. It begins by examining the social and ecological costs of and limits to economic growth and determines that significant decarbonisation of the global economy can only be achieved if conventional growth-based economies are replaced by an alternative post-growth economy.Set apart from many other works in the field by its critical political economy approach to policy development, this book offers the reader three distinctive features. First, it places the analysis in historical context in order to demonstrate how the global political economy is constantly changing with respect to distributions of wealth, power and fundamental norms, and explores how states might harness and transform these contingent patterns in a post-growth direction. Second, the book is not only concerned with developing and advocating post-growth policies, but also with how these measures can be incorporated into the high-level domestic and international strategies pursued by states to ensure their political legitimacy and economic and geopolitical survival. Third, rather than proposing an idealised and politically naïve model of socioecological transformation, the proposed post-growth policy framework is highly cognisant of the geopolitical and international economic pressures facing states and demonstrates how these can be managed in the transition toward a post-growth economy.This book represents an invaluable resource for policymakers, academics, activists and students wishing to study or contribute to the transition to a post-growth, decarbonised economy.
Post-harvest Pathology: Plant Pathology in the 21st Century, Contributions to the 10th International Congress, ICPP 2013
by Maria Lodovica Gullino Dov PruskyThis collection of papers includes some of the presentation given at the International congress of Plant Pathology held in Beijing in 2013 in the session of Recent Development in Postharvest Pathology. Fruit production for human consumption is an important part of the market economy. Any waste during to spoilage and pest infestation, in the field and the postharvest phase, results in significant economic losses which are more pronounced as the losses occur closer to the time of produce sale. Careful handling of perishable produce is needed for the prevention of postharvest diseases at different stages during harvesting. Handling, transport and storage in order to preserve the high quality produce. The extent of postharvest losses varies markedly depending on the commodities and country estimated to range between 4 and 8% in countries where postharvest refrigeration facilities are well developed to 30% where facilities are minimal. Microbial decay is one of the main factors that determine losses compromising the quality of the fresh produce. For the development of an integrated approach for decay management, cultural, preharvest, harvest and postharvest practices should be regarded as essential components that influence the complex interactions between host, pathogen, and environmental conditions. Orchards practices including preharvest fungicide applications can also directly reduce the development of postharvest fruit decay. Among postharvest practices, postharvest fruit treatments with fungicide are the most effective means to reduce decay. Ideally, these fungicides protect the fruit from infections that occur before treatment, including pathogen causing quiescent infections, as well from infection that are initiated after treatment during postharvest handling, shipment and marketing. The implementation of these alternatives techniques often requires modifying currently used postharvest practices and development of new formulation for their applications. The present chapters deal with the newest report related to postharvest pathology in the world.
Post-harvest Pathology: 2 (Plant Pathology in the 21st Century)
by Dov Prusky Maria Lodovica GullinoAs a collection of papers that includes material presented at the 2008 International Congress for Plant Pathology, this text features research right at the leading edge of the field. The latest findings are particularly crucial in their implications for fruit production; an important market sector where in some areas up to 50 per cent of the crop can be lost after harvest. While post-harvest fruit treatments with fungicides are the most effective means to reduce decay, rising concerns about toxicity have led to the development of alternative approaches to disease control, including biological methods, the subject of three chapters of this book. With several new techniques requiring modification of current post-harvest practices, it is more important than ever to stay abreast of the latest information. Other chapters deal with the mechanisms of host fruit and vegetable resistance, fungal pathogenicity factors and their relationship with the host response, and a number of subjects related to disease assessments before harvest as well as their relationship to the postharvest treatment of fruits and vegetables. The book also includes several useful case studies of crops such as kiwifruit and peaches, where different approaches at the pre- and post-harvest levels are combined to good effect. With food production issues gaining an ever higher profile internationally, this text makes an important contribution to the debate.
Post-Harvest Processing, Packaging and Inspection of Frozen Shrimp: A Practical Guide
by Md. Abdul Hannan Kazi Ahsan Habib A. M. Shahabuddin Md. Ariful Haque Mohammad Bodrul MunirThe book is a practical guide for the various steps in the post-harvest technology of frozen shrimps. Shrimps are one of the most common and popular types of seafood consumed globally. The book discusses some of the most sought-after shrimps such as Penaeus monodon, P. vannamei, and Macrobrachium rosenbergii. Good-quality shrimp is a prerequisite for the seafood business as it is used for human consumption. Lack of proper knowledge in raw materials handling and post-harvest processing is the main obstacle in quality shrimp production. Complex business policy, commitment break in both parties (buyers and sellers), competition with other seafood-producing countries, and fluctuation of currency in international seafood market are the factors affecting international seafood business. This book closes this gap in literature and facilitates the production of excellent-quality exportable frozen shrimp through informed practices from experts. The book includes information about packaging of frozen shrimp, inspection, and shipment. It also compiles different mathematical calculations which are in practiced in the processing industries. The book is essential reading for professionals in the shrimp producing and processing industries. It is also useful for researchers in fisheries science, aquaculture, food technology, and food microbiology.
Post Mortem CT for Non-Suspicious Adult Deaths: An Introduction
by Ayeshea Shenton Peter Kralt S. Kim SuvarnaThis book is an ideal introduction to the specialty of post mortem computed tomography (PMCT). It will serve as a comprehensive yet accessible guide to the understanding and interpretation of whole-body studies for both hospital and community settings. Both normal post mortem appearances and findings associated with a wide range of diagnoses encountered in real cases from the coronial service are presented with the aid of numerous images. The coverage encompasses not only findings in all anatomic regions but also the imaging appearances in cases following targeted coronary angiography, attempted cardiopulmonary resuscitation and various special circumstances such as suicide. The inclusion of many practical tips and possible pitfalls will support the radiologist to become more confident when reporting PMCT, while for the more experienced practitioner the wealth of examples will serve as a useful resource. In addition to radiologists, the book will be of value for pathologists at all levels of experience and anyone needing to understand the role and limitations of PMCT.
Post-Oil Energy Technology: The World's First Solar-Hydrogen Demonstration Power Plant
by Bela G. LiptakA solution to the climate and energy crisisThe reversible fuel cell (RFC) described in this volume stores solar energy and thereby makes it continuously available. This can make the building of energy-free homes and all electric transportation a reality. The foldout drawing at the back of this book also describes the detailed design of the world’s first 1,000 megawatt solar-hydrogen power plant. How is this possible?Our planet receives more solar energy in an hour than humans use in a year. In fact, 5% of the Sahara could meet the total energy requirement of mankind. This energy can then be stored and transported in the form of hydrogen. Converting from an exhaustible energy economy to a clean, free, and inexhaustible oneIn this timely book, author Béla Lipták explains why a solar-hydrogen economy is technically feasible and cost-effective. He first outlines existing conservation technologies and renewable energy processes as well as evolving technologies, such as energy-free homes, roof shingle solar collectors, and RFCs. He goes on to discuss energy optimization techniques that could reduce the global energy consumption by one third and finally presents the detailed design of a full size solar-hydrogen power plant. It is time to harness the power of solar energyWith global energy consumption quadrupling in the last fifty years and atmospheric carbon dioxide reaching the highest level ever recorded, now is the time to prevent further damage to the planet and ensure the survival of human civilization. It is debatable how much time we have before our fossil and uranium deposits are exhausted. It is also debatable how much climate change we can live with or how much of our economic resources should be devoted to stabilizing and reversing mankind’s growing carbon footprint. What is not debatable is that our resources are exhaustible and that we must not give reason for our grandchildren to ask, "Why did you not act in time?".
The Post-Pandemic World: Sustainable Living on a Wounded Planet
by John Erik MeyerThe Covid-19 pandemic is a repeating biophysical shock yet one for which our current socio-economic structure was not prepared. Climate change, scarcity, depletion of natural resources, and the inevitable transition to renewable energy are one time events. Taken together, they present an existential threat to human society. This book is a guide to navigating these megatrends, which confront us now but whose consequences will unfold over decades. By presenting clear options on the path to a renewable energy future, this book gives readers a broad perspective as well as detailed, well-illustrated examples to weigh in making decisions which will secure stability and prosperity for their families, their communities and their nations.
Post-Transcriptional Gene Regulation
by Erik DassiThis volume aims to provide the most recent advances in techniques for studying gene expression regulation at the post-transcriptional level. Post-Transcriptional Gene Regulation, Second Edition is organized in six sections describing bioinformatics approaches for studying post-transcriptional regulation, various expression profiling approaches, protein-RNA interaction and non-coding RNA investigation techniques, methods for profiling RNA modifications, and other techniques such as alternative translation initiation or polyadenylation sites determination. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Post-Transcriptional Gene Regulation, Second Edition is a versatile resource to researchers studying post-transcriptional regulation, introducing the most recent techniques and providing a comprehensive guide to their implementation.