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Post-Transcriptional Gene Regulation (Methods in Molecular Biology #2404)
by Erik DassiThis volume presents the most recent advances in techniques for studying the post-transcriptional regulation of gene expression (PTR). With sections on bioinformatics approaches, expression profiling, the protein and RNA interactome, the mRNA lifecycle, and RNA modifications, the book guides molecular biologists toward harnessing the power of this new generation of techniques, while also introducing the data analysis skills that these high-throughput techniques require. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Post-Transcriptional Gene Regulation, Third Edition serves as a versatile resource for researchers studying post-transcriptional regulation by both introducing the most recent techniques and providing a comprehensive guide to their implementation. Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Post-Transcriptional Gene Regulation
by Jeffrey WiluszThis volume strives to present current technical approaches to most aspects of post-transcriptional control and provide the reader with a useful and versatile laboratory bench resource. With chapters split into sections covering bioinformatics, fundamental aspects of the study of RNA biology, and techniques for specific aspects of RNA biology, the expert authors have filled the book with invaluable tricks of the trade, perfected in their laboratories.
Post-Translational Modification of Proteins: Tools for Functional Proteomics (Methods in Molecular Biology #1934)
by Christoph KannichtThe majority of all proteins undergo co- and/or post-translational modifications, crucially altering physical and chemical properties, folding, conformation distribution, stability, activity, and, consequently, the function of the proteins. In Post-Translational Modifications of Proteins: Tools for Functional Proteomics, Third Edition this important area of research is brought up-to-date by the leading scientists in the field. This compilation of detailed protocols focuses on protein function, proteome research and characterization of pharmaceutical proteins, while following the successful format of the Methods in Molecular Biology series. Each chapter provides a brief introduction to the topic, step-by-step laboratory protocols, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and cutting edge, Post-Translational Modifications of Proteins: Tools for Functional Proteomics, Third Edition serves as practical guide for researchers working in the field of protein structure-function relationships and the rapidly growing field of proteomics, as well as scientists in the pharmaceutical industries.
Post-Translational Modifications in Health and Disease
by Cecilio J. VidalPost-translational modifications serve many different purposes in several cellular processes such as gene expression, protein folding and transport to appropriate cell compartment, protein-lipid and protein-protein interactions, enzyme regulation, signal transduction, cell proliferation and differentiation, protein stability, recycling and degradation. Although several-hundred different modifications are known, the significance of many of them remains unknown. The enormous versatility of the modifications which frequently alter the physico-chemical properties of the respective proteins represents an extraordinary challenge in understanding their physiological role. Since essential cellular functions are regulated by protein modifications, an improvement of current understanding of their meaning might allow new avenues to prevent and/or alleviate human and animal diseases.
Post-translational Modifications of Proteins
by John J. Harding M. James CrabbePost-Translational Modifications of Proteins discusses several important topics of interest to researchers and students in protein chemistry and biochemistry, including the occurrence and function of hydroxylated residues and the three enzymes required for their formation; the damaging effects of reactions between sugars and proteins; ADP-riboosylation of proteins outside the nucleus; and Monod, Wyman, and Changeux's concerted model for allosteric control of enzyme activity exemplified by studies on glycogen phosphorylase. The application of Fast Atom Bombardment Mass Spectometry (FAB-MS) to studies on the structure and biosynthesis of various oligosaccharide moieties in protein is examined, and the understanding of the structural diversity and function of glycoprotein oligosaccharides is discussed in this volume.
Post-Traumatic Stress Disorder and the Earnings of Military Reservists
by David S. Loughran Paul HeatonAn investigation of the effects of having symptoms of post-traumatic stress disorder (PTSD) on the labor market earnings of reservists in the years following deployment.
Post-Truth Imaginations: New Starting Points for Critique of Politics and Technoscience (History and Philosophy of Technoscience)
by Kjetil RommetveitThis book engages with post-truth as a problem of societal order and for scholarly analysis. It claims that post-truth discourse is more deeply entangled with main Western imaginations of knowledge societies than commonly recognised. Scholarly responses to post-truth have not fully addressed these entanglements, treating them either as something to be morally condemned or as accusations against which scholars have to defend themselves (for having somehow contributed to it). Aiming for wider problematisations, the authors of this book use post-truth to open scholarly and societal assumptions to critical scrutiny. Contributions are both conceptual and empirical, dealing with topics such as: the role of truth in public; deep penetrations of ICTs into main societal institutions; the politics of time in neoliberalism; shifting boundaries between fact – value, politics – science, nature – culture; and the importance of critique for public truth-telling. Case studies range from the politics of nuclear power and election meddling in the UK, over smart technologies and techno-regulation in Europe, to renewables in Australia. The book ends where the Corona story begins: as intensifications of Modernity’s complex dynamics, requiring new starting points for critique.
Post Un-Lock: From Territorial Vulnerabilities to Local Resilience (The Urban Book Series)
by Grazia Brunetta Patrizia Lombardi Angioletta VogheraThis open access book builds a framework that holds together numerous open issues in territorial planning: from the understanding of territorial, landscape, environmental and climatic dynamics to the analysis of local vulnerabilities, to the use of modern survey techniques to support planning. What is the role of urban and regional planning in achieving the sustainable development goals of our communities considering the major issues posed by the COVID-19 pandemic in urban planning? And how do these medium- and long-term objectives interact with the needs that the emergency has given rise to? Post Un-Lock—from territorial vulnerabilities to local resilience—aims to provide the reader with a useful key to understand how the COVID-19 pandemic can be seen as a catalyst for a restart based on the concepts of sustainability and resilience. In fact, the COVID-19 experience evidences the need to propose a planning system able to integrate multiple scales according to an interdisciplinary approach focused on in-depth knowledge of the territorial risks and vulnerabilities. Besides, with the contribution of the new technologies, it is able to rethink spaces on a neighbourhood scale, conceived as a "local resilience unit" that ensures the population high standards of safety, liveability, and accessibility to proximity services. In this view, planning is increasingly concerned about social aspects and the well-being of communities, supported by indicators and evaluation tools. With the proposal of the concept of local resilience unit, Post Un-Lock takes a step forward towards the definition of a new paradigm of local planning and a topic for urban regeneration.
Postbiotics (Methods and Protocols in Food Science)
by Dhanasekaran DharumaduraiThis volume details preparations, separations, identification, analysis of postbiotics types and mechanism, uses of postbiotics in health, pharma, aquacultures, and the food industry. Divided into five sections chapters provide methods on antimicrobials, antibiofilm, anti-inflammatory, antiallergies, antiobesity, meurotransmitter activity, dietary supplementation and Immunomodulatory activity of postbiotics, postbiotics as biopreservatives , and as well as food packing material. . Written in the format of the Methods and Protocols in Food Science series, chapters list necessary materials and methods for readily reproducible protocols. Authoritative and cutting-edge, Postbiotics aims to be a foundation for future studies and to be a source of inspiration for new investigations in the field.
The Postcranial Anatomy of Australopithecus afarensis
by Yohannes Haile-Selassie Denise F. SuThis volume describes a 3. 6 million-years-old partial skeleton of Australopithecus afarensis from the Woranso-Mille, central Afar, Ethiopia. This specimen is the first adult partial skeleton to be recovered since Lucy's (A. L. 288-1) discovery in 1974. It is older than Lucy by 400,000 years and sheds light on the paleobiology of early Australopithecus afarensis, particularly the morphology of the shoulder girdle and thoracic shape, which are thus far poorly understood and actively debated. The fauna associated with the partial skeleton tells us enormously about Au. afarensis paleoecology and give us another piece of the puzzle regarding habitat availability and use for Au. afarensis outside the Hadar region where it has been well-known for the last four decades.
The Postgenomic Condition: Ethics, Justice, & Knowledge after the Genome
by Jenny ReardonNow that we have sequenced the human genome, what does it mean? In The Postgenomic Condition, Jenny Reardon critically examines the decade after the Human Genome Project, and the fundamental questions about meaning, value and justice this landmark achievement left in its wake. Drawing on more than a decade of research—in molecular biology labs, commercial startups, governmental agencies, and civic spaces—Reardon demonstrates how the extensive efforts to transform genomics from high tech informatics practiced by a few to meaningful knowledge beneficial to all exposed the limits of long-cherished liberal modes of knowing and governing life. Those in the American South challenged the value of being included in genomics when no hospital served their community. Ethicists and lawyers charged with overseeing Scottish DNA and data questioned how to develop a system of ownership for these resources when their capacity to create things of value—new personalized treatments—remained largely unrealized. Molecular biologists who pioneered genomics asked whether their practices of thinking could survive the deluge of data produced by the growing power of sequencing machines. While the media is filled with grand visions of precision medicine, The Postgenomic Condition shares these actual challenges of the scientists, entrepreneurs, policy makers, bioethicists, lawyers, and patient advocates who sought to leverage liberal democratic practices to render genomic data a new source of meaning and value for interpreting and caring for life. It brings into rich empirical focus the resulting hard on-the-ground questions about how to know and live on a depleted but data-rich, interconnected yet fractured planet, where technoscience garners significant resources, but deeper questions of knowledge and justice urgently demand attention.
Postgenomics: Perspectives on Biology after the Genome
by Hallam Stevens Sarah S. RichardsonTen years after the Human Genome Project's completion the life sciences stand in a moment of uncertainty, transition, and contestation. The postgenomic era has seen rapid shifts in research methodology, funding, scientific labor, and disciplinary structures. Postgenomics is transforming our understanding of disease and health, our environment, and the categories of race, class, and gender. At the same time, the gene retains its centrality and power in biological and popular discourse. The contributors to Postgenomics analyze these ruptures and continuities and place them in historical, social, and political context. Postgenomics, they argue, forces a rethinking of the genome itself, and opens new territory for conversations between the social sciences, humanities, and life sciences.Contributors. Russ Altman, Rachel A. Ankeny, Catherine Bliss, John Dupré, Michael Fortun, Evelyn Fox Keller, Sabina Leonelli, Adrian Mackenzie, Margot Moinester, Aaron Panofsky, Sarah S. Richardson, Sara Shostak, Hallam Stevens
Postharvest: An Introduction to the Physiology and Handling of Fruit and Vegetables (Cabi Publishing Ser.)
by Ron Wills John GoldingCompletely updated, this broad-based introductory level textbook covers the key concepts and practical technologies to slow the deterioration of harvested produce, including handling, packaging, transport, temperature management and the control of pests and diseases. The book retains the high quality colour section and the content has been revised to reflect up-to-date information on the key issues of effective postharvest handling. New to the sixth edition: - Discussion of issues important to consumers and the impact of trends in convenience marketing on the quality of fresh-cut produce - Coverage of sustainability in terms of both energy used by technologies and non-synthetic disease and pest control systems - Greater consideration given to pre-harvest factors that influence quality - Additional information about the health benefits of plant antioxidant properties and a discussion of 'superfoods' This new edition is an invaluable resource for students of horticulture, plant physiology and food science, and industry personnel involved with the transportation, warehousing, marketing and retailing of fresh produce.
Postharvest Biology and Nanotechnology (New York Academy of Sciences)
by Gopinadhan Paliyath Jayasankar Subramanian Loong-Tak Lim K. S. Subramanian Avtar K. Handa Autar MattooA comprehensive introduction to the physiology, biochemistry, and molecular biology of produce growth, paired with cutting-edge technological advances in produce preservation Revised and updated, the second edition of Postharvest Biology and Nanotechnology explores the most recent developments in postharvest biology and nanotechnology. Since the publication of the first edition, there has been an increased understanding of the developmental physiology, biochemistry, and molecular biology during early growth, maturation, ripening, and postharvest conditions. The contributors—noted experts in the field—review the improved technologies that maintain the shelf life and quality of fruits, vegetables, and flowers. This second edition contains new strategies that can be implemented to remedy food security issues, including but not limited to phospholipase D inhibition technology and ethylene inhibition via 1-MCP technology. The text offers an introduction to technologies used in production practices and distribution of produce around the world, as well as the process of sencescence on a molecular and biochemical level. The book also explores the postharvest value chain for various produce, quality evaluation techniques, and the most current nanotechnology applications. This important resource: • Expands on the first edition to explore in-depth postharvest biology with emphasis on developments in nanotechnology • Contains contributions from leaders in the field • Includes the most recent advances in postharvest biology and technology, including but not limited to phospholipase D and 1-MCP technology • Puts the focus on basic science as well as technology and practical applications • Applies a physiology, biochemistry, and biotechnology approach to the subject Written for crop science researchers and professionals, horticultural researchers, agricultural engineers, food scientists working with fruits and vegetables, Postharvest Biology and Nanotechnology, Second Edition provides a comprehensive introduction to this subject, with a grounding in the basic science with the technology and practical applications.
Postharvest Biology and Technology of Temperate Fruits
by Mohammad Maqbool Mir Shabir Ahmad Mir Manzoor Ahmad ShahThis edited volume provides insight into temperate fruits, with an emphasis on postharvest physiology, storage, packaging and technologies for maintaining fruit quality. Chapters are devoted to individual fruits and focus on fundamental issues such as methods for maintaining or enhancing quality, minimizing postharvest losses, and recommended technologies to boost demand. Contributions come from experts in the field, making this a key reference for all aspects of postharvest management of temperate fruits.The volume is unique in its focus on the biodiversity, nutritional and health benefits, and postharvest technologies for shelf life enhancement of temperate fruits. Contributing authors address the postharvest biology and technology of individual temperate fruits such as plum, cherry, peach, apricot, apple, pear, quince, loquat, kiwi, persimmon and berries. There has been tremendous growth in the research and development of new techniques to maintain the quality of temperate fruits from farm to table. Contributions from experts in the field cover these recent advances, providing up-to-date and relevant information for researchers, postharvest/fruit technologists, food scientists, postgraduate students, and others working in the industry.
Postharvest Handling and Diseases of Horticultural Produce
by Dinesh SinghPostharvest Handling and Diseases of Horticultural Produce describes all the postharvest techniques, handling, pre-cooling, postharvest treatment, edible coating and storage of the horticultural produce available to handle perishable horticultural food commodities, covering the areas of horticulture, agricultural process engineering, postharvest technology, plant pathology and microbiology. Postharvest diseases of major fruits and vegetables, with their causal agents, are described. The integrative strategies for management of postharvest diseases include effectively inhibiting the growth of pathogens, enhancing the resistance of hosts and improving environmental conditions, with results that are favourable to the host and unfavourable to the pathogen growth including biotechnological approaches. Adopting a thematic style, chapters are organized by type of treatment, with sections devoted to postharvest risk factors and their amelioration. The chapters are written by experts in the fields of plant pathology, horticulture, food science etc., and core insights into identifying and utilizing appropriate postharvest options for minimizing postharvest losses and enhancing benefits to end-users are provided. Features Presents the most recent developments in the field of postharvest handling technologies and diseases in a single volume Includes postharvest diseases of cut flowers, fruits, vegetables and tuber crops. Appropriate for students, researchers and professionals Written by experts and can be used as a reference resource
Postharvest Handling of Horticultural Crops
by Raju L. Bhardwaj Yogesh Kumar Sharma Latika VyasThis book covers the importance of post-harvest technology in horticultural crops, fruit growth, development and post harvest physiology, fruit maturity indices, harvesting of fruits and vegetables, initial handling of fruits and vegetable after harvesting, precooling of horticulture produce, transportation, etc.. It is a rich source of modern engineering technologies for income generating concept for agro based industries. The book is specially dedicated to the sub sector of the fruits and vegetables plants dealing with the fresh primary product from the product reception following the harvesting up-to the storage and before launches it to the market. This book will serves as a comprehensive guide for all the people who focuses on post harvest management skills.Note: T&F does not sell or distribute the hardback in India, Pakistan, Nepal, Bhutan, Bangladesh and Sri Lanka.
Postharvest Nanotechnology for Fresh Horticultural Produce: Innovations and Applications (Innovations in Postharvest Technology Series)
by Radhakrishnan E. K. Ashitha Jose Sunil PareekFood scarcity and insecurity is an alarming issue throughout the world. Postharvest loss due to both mechanical damage and microbial spoilage significantly influences the shelf life and hence the availability of agricultural produce. Once initiated, the microbial spoilage can make bulk quantity of a given agricultural product unacceptable for human consumption, and several methods have already been used to try to manage this. Considering the limited success of the available methods, there is increasing interest in exploring nanotechnological methods. These methods are being considered for both the development of various platforms for antimicrobial/barrier packaging applications that minimize the contact of agricultural produce with the external environment, and also for design sensors to ensure food safety and quality. The impact of various nano-systems developed through material engineering on the shelf-life enhancement and storage of fresh horticultural produce will have revolutionary effects on post-harvest management in the coming years. Hence, Postharvest Nanotechnology for Fresh Horticultural Produce has been edited to advance understanding of material development, intelligent selection of nanomaterials to ensure the nontoxic nature, and future perspectives of nanotechnology on postharvest produce. This includes various types of nanoparticles exploited for the postharvest management, their mechanism of action, varied applications and material engineering, along with natural products including essential oils and plant bioactives, modelling of various tailor-made materials to meet the required properties of the packed food, advancements in the nanotechnological applications for the minimally processed food, and the toxicity concerns. Key Features: · Describes advances in nanotechnology for postharvest management · Includes extensive details on the applications of material engineering for post-harvest applications using nanotechnology and future aspects · Provides extensive data on the types of nanomaterials used and the fabrication methods employed for the design of tailor-made products for the post-harvest management This book reviews the current scientific advancements and future prospects of the nanotechnological interventions in meeting the quality and quantity standards of the horticultural produce and minimally processed food and will be a valuable reference for beginners, researchers, subject experts, and industrialists.
Postharvest Pathology: Next Generation Solutions to Reducing Losses and Enhancing Safety (Plant Pathology in the 21st Century #11)
by Davide Spadaro Samir Droby Maria Lodovica GullinoThe book will address selected topics in postharvest pathology aiming at highlighting recent development in the science, technology and control strategies of postharvest diseases to reduce losses and enhance safety of harvested agricultural products. Topics will include: 1) Introduction: Perspectives and challenges in postharvest pathology 2) Elucidating host-pathogen interactions 3) Next generation technologies for management and detection of postharvest pathogens 4) Food safety in postharvest pathology 5) Alternative postharvest diseases control strategies 6) Chemical control of postharvest diseases
Postharvest Physiology and Handling of Horticultural Crops
by İbrahim KahramanoğluThe increase in global population compels growers to use excessive fertilizers to enhance agricultural production. Excessive fertilizer use may also negatively affect the nutritional quality and preservation of horticultural products, reducing the shelf life and overall quality of fruits and vegetables. Postharvest Physiology and Handling of Horticultural Crops contains fundamental information that helps readers understand postharvest physiology of fresh fruits and vegetables, and presents an in-depth analysis of the harmful impacts of agrochemicals. The book presents readers with eco-friendly, innovative techniques used to handle the fruits and vegetables during storage and through supply chains helping to better preserve them. Features · Describes available technologies to eliminate and minimize microbial infection for maintaining postharvest quality and safety of fresh produce. · Explores and discusses approaches, technologies, and management practices necessary to maintain products’ storage quality by ensuring food safety and nutrition retention. · Provides practical applications of latest developments in disinfection applications, smart packaging, nano-enabled applications, advances in fresh-cut products, light illumination and edible coatings. · Presents an in-depth discussion of the harmful impacts of agrochemicals and aims to introduce new, eco-friendly and innovative technologies to the readers. With chapters written by experts in the field of postharvest fruit and vegetable preservation, this book provides information on the use of biomaterials in food preservation and provides practical information for students, teachers, professors, scientists, farmers, food packers and sellers; as well as entrepreneurs engaged in the fresh food preservation industry.
Postharvest Physiology and Pathology of Vegetables
by Jerry A. Bartz Jeffrey K. BrechtFocusing exclusively on postharvest vegetable studies, this book covers advances in biochemistry, plant physiology, and molecular physiology to maximize vegetable quality. The book reviews the principles of harvest and storage; factors affecting postharvest physiology, calcium nutrition and irrigation control; product quality changes during handling and storage; technologies to improve quality; spoilage factors and biocontrol methods; and storage characteristics of produce by category. It covers changes in sensory quality such as color, texture, and flavor after harvest and how biotechnology is being used to improve postharvest quality.
Postharvest Plant Pathology
by N.G. RavichandraThe purpose of the book Postharvest Plant Pathology is to provide its readers recent developments and updated comprehensive information on postharvest pathogens & diseases of major crops. This book explicates the fundamental aspects of postharvest diseases of crops and is conveniently divided into ten chapters, providing the latest information on the concept & types of postharvest diseases, economically significant postharvest pathogens & diseases of major crops, factors governing postharvest diseases, storage conditions, food safety issues, quiescence in post harvest pathogens, detailed & recent information on major mycotoxins, various approaches of postharvest disease management, integrated management strategies, biochemical & molecular aspects of postharvest diseases, apart from which, an exclusive chapter for discussing the postharvest nematode diseases and their management is also furnished.Note: T&F does not sell or distribute the hardback in India, Pakistan, Nepal, Bhutan, Bangladesh and Sri Lanka. This title is co-published with NIPA.
Postharvest Technology of Horticultural Crops
by Priya Awasthi Subhash Chandra Singh Rohit KumarThis book is an informative introduction to the post-harvest technology of horticultural crops, and their conservation and management. The different post-harvest handling operations including storage aspects are also covered. Innovative processing technologies like high-pressure processing, irradiation, cold plasma technique and ohmic heating are also discussed in the book.
Posthuman Property and Law: Commodification and Control through Information, Smart Spaces and Artificial Intelligence
by Jannice KällThis book analyses the phenomenon of digitally mediated property and considers how it problematises the boundary between human and nonhuman actors. The book addresses the increasingly porous border between personhood and property in digitized settings and considers how the increased commodification of knowledge makes visible a rupture in the liberal concept of the property owning, free, person. Engaging with the latest work in posthumanist and new materialist theory, it shows, how property as a concept as well as a means for control, changes fundamentally under advanced capitalism. Such change is exemplified by the way in which data, as an object of commodification, is extracted from human activities yet is also directly used to affectively control – or nudge – humans. Taking up a range of human engagements with digital platforms and coded architectures, as well as the circulation of affects through practices of artificial intelligence that are employed to shape behaviour, the book argues that property now needs to be understood according to an ecology of human as well as nonhuman actors. The idea of posthuman property, then, offers both a means to critique property control through digital technologies, as well as to move beyond the notion of the self-owning, object-owning, human. Engaging the most challenging contemporary technological developments, this book will appeal to researchers in the areas of Law and Technology, Legal Theory, Intellectual Property Law, Legal Philosophy, Sociology of Law, Sociology, and Media Studies.
Posthuman Spiritualities in Contemporary Performance: Politics, Ecologies and Perceptions
by Silvia BattistaThis book provides an interpretative analysis of the notion of spirituality through the lens of contemporary performance and posthuman theories. The book examines five performance/artworks: The Artist is Present (2010) by Marina Abramović; The Deer Shelter Skyscape (2007) by James Turrell; CAT (1998) by Ansuman Biswas; Journey to the Lower World by Marcus Coates (2004); and the work with pollen by Wolfgang Laib. Through the analysis of these works the notion of spirituality is grounded in materiality and embodiment allowing the conceptual juxtaposition of spirit and matter to introduce the paradoxical as the guiding thread of the narrative of the book. Here, the human is interrogated and negotiated with/within a plurality of other living organisms, intangible existences and micro and macrocosmic ecologies. Silence, meditation, shamanic journeys, reciprocal gazing, restraint, and contemplation are analyzed as technologies used to manipulate perception and adventure into the multilayered condition of matter.