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Policy Issues in the Development and Adoption of Biomarkers for Molecularly Targeted Cancer Therapies: Workshop Summary
by Sharyl J. NassA long-held goal in oncology has been to develop therapies that target the specific abnormalities in each patient's cancer rather than simply treating cancers based on the tissue of origin. In the past decade, advances in technology have enabled researchers to relatively quickly and inexpensively determine, in minute detail, the genetic makeup of tumors. Although relatively few targeted cancer therapies are currently available in the clinic and it is not yet clear whether all cancers are driven by genetic changes that can be targeted, there is widespread optimism in the cancer community that this new ability to assess the genetic abnormalities in tumors will ultimately lead to better cancer treatments and improved patient outcomes. "Policy Issues in the Development and Adoption of Biomarkers for Molecularly Targeted Cancer Therapies" is the summary of a workshop convened in November 2014 by the Institute of Medicine's National Cancer Policy Forum to discuss recent trends in the development and implementation of molecularly targeted cancer therapies and explore potential policy actions to address specific challenges. This report highlights the presentations and discussions at the workshop.
Policy Legitimacy, Science and Political Authority: Knowledge and action in liberal democracies (The Earthscan Science in Society Series)
by Michael Heazle John KaneVoters expect their elected representatives to pursue good policy and presume this will be securely founded on the best available knowledge. Yet when representatives emphasize their reliance on expert knowledge, they seem to defer to people whose authority derives, not politically from the sovereign people, but from the presumed objective status of their disciplinary bases. This book examines the tensions between political authority and expert authority in the formation of public policy in liberal democracies. It aims to illustrate and better understand the nature of these tensions rather than to argue specific ways of resolving them. The various chapters explore the complexity of interaction between the two forms of authority in different policy domains in order to identify both common elements and differences. The policy domains covered include: climate geoengineering discourses; environmental health; biotechnology; nuclear power; whaling; economic management; and the use of force. This volume will appeal to researchers and to convenors of post-graduate courses in the fields of policy studies, foreign policy decision-making, political science, environmental studies, democratic system studies, and science policy studies.
Policy Network Ties in the Dynamic Process of Environmental Conflict Resolution: Uncovering the Evolution of Environmental Governance (Environment & Policy #60)
by Seunghoo LimExtensive previous research has investigated environmental conflict management issues in networked settings and the design of policy networks, but the emergence and evolution of self-organizing policy networks are still not fully understood. Especially misunderstood is the problem of how the multiple motivations or incentives of competing policy actors in conflictual situations affect their structures of interaction, as this issue has not been studied systematically. This book aims to address the following research questions: how do policy stakeholders cope strategically with collective action or environmental conflict resolution? How do they utilize or maintain formal and informal policy networks to resolve problems effectively? What motivates them to engage or be involved in collaborative or conflictual networks? What influences their networking or their decisions on partner selection for conflict resolution? This book consists of four studies. The goal of the first study is to examine the form of a policy network by focusing on how policy networks emerge and evolve at the micro-level to solve collective action dilemmas endemic to decentralized and democratized policy decision-making processes, particularly in the environmental conflict resolution arena. The goal of the second study is to examine the main policy actors and structural characteristics of network governance evolution in the dynamic process of environmental conflict resolution. The goal of the third study is to highlight the role of policy tie formality in the evolution of multiplex ties in the environmental conflict resolution process. The goal of the fourth study is to demonstrate the relationships between patterns of interactions among policy actors and their modified and adjusted strategic behaviours within policy networks and across advocacy coalitions.
Policy-Oriented Technology Assessment Across Europe: Expanding Capacities
by Lars Klüver Rasmus Øjvind Nielsen Marie Louise JørgensenPolicy-Oriented Technology Assessment Across Europe.
Policy-Oriented Technology Assessment Across Europe: Expanding Capacities
by Lars Klüver Rasmus Øjvind Nielsen Marie Louise JørgensenThis book is open access under a CC-BY license. Policy-making to address grand challenges faces greater complexity than any previous project of modernization. Future scenarios are haunted by uncertainty and there is real ambivalence as to the values that policy should strive for. In this situation decision-makers look to research and innovation to provide answers and solutions. But neither can the great transitions ahead be planned by science, nor will conventional methods of innovation bring such transitions about. A turn to interactive governance is therefore underway with policy-makers and citizens becoming increasingly involved in processes of deliberating futures. Technology Assessment (TA) is the art of structuring such processes. TA goes beyond traditional expert policy analysis by systematically combining a multi-disciplinary evidence base with participatory approaches to policy deliberation. TA thus seeks to act as a hub for serious and transparent dialogue between policy, industry, science, and society about the challenges ahead and the available options for overcoming them responsibly. This volume offers an up-to-date account of the expansion of technology assessment capacities across new European member states. The contributions of this volume are written by leading European researchers and practitioners in technology assessment (TA) and are based on the PACITA (Parliaments and Civil Society in Technology Assessment) project.
Polio: An American Story
by David M. OshinskyAll who lived in the early 1950s remember the fear of polio and the elation felt when a successful vaccine was found. Now David Oshinsky tells the gripping story of the polio terror and of the intense effort to find a cure, from the March of Dimes to the discovery of the Salk and Sabin vaccines - and beyond. Here is a remarkable portrait of America in the early 1950s, using the widespread panic over polio to shed light on our national obsessions and fears. Drawing on newly available papers of Jonas Salk, Albert Sabin and other key players, Oshinsky paints a suspenseful portrait of the race for the cure, weaving a dramatic tale centered on the furious rivalry between Salk and Sabin. Indeed, the competition was marked by a deep-seated ill will among the researchers that remained with them until their deaths. The author also tells the story of Isabel Morgan, perhaps the most talented of all polio researchers, who might have beaten Salk to the prize if she had not retired to raise a family. As backdrop to this feverish research, Oshinsky offers an insightful look at the National Foundation for Infantile Paralysis, which was founded in the 1930s by FDR and Basil O'Connor. The National Foundation revolutionized fundraising and the perception of disease in America, using "poster children" and the famous March of Dimes to raise hundreds of millions of dollars from a vast army of contributors (instead of a few well-heeled benefactors), creating the largest researchand rehabilitation network in the history of medicine. The polio experience also revolutionized the way in which the government licensed and tested new drugs before allowing them on the market, and the way in which the legal system dealt with manufacturers' liability for unsafe products. Finally, and perhaps most tellingly, Oshinsky reveals that polio was never the raging epidemic portrayed by the media, but in truth a relatively uncommon disease. But in baby-booming America - increasingly suburban, family-oriented, and hygiene-obsessed - the specter of polio, like the specter of the atomic bomb, soon became a cloud of terror over daily life. Both a gripping scientific suspense story and a provocative social and cultural history, Polio opens a fresh window onto postwar America.<P><P> Pulitzer Prize Winner
The Polio Pioneer: Dr. Jonas Salk and the Polio Vaccine
by Linda Elovitz MarshallA SYDNEY TAYLOR NOTABLE BOOK • Learn about the importance of vaccines and the scientific process through the fascinating life of world-renowned scientist Jonas Salk, whose pioneering discoveries changed the world forever.Dr. Jonas Salk is one of the most celebrated doctors and medical researchers of the 20th century. The child of immigrants who never learned to speak English, Jonas was struck by the devastation he saw when the soldiers returned from battle after WWII. Determined to help, he worked to become a doctor and eventually joined the team that created the influenza vaccine. But Jonas wanted to do more. As polio ravaged the United States--even the president was not immune!--Jonas decided to lead the fight against this terrible disease. In 1952, Dr. Jonas Salk invented the polio vaccine, which nearly eliminated polio from this country. For the rest of his life, Dr. Salk continued to do groundbreaking medical research at the Salk Institute, leaving behind a legacy that continues to make the world a better place every day.This compelling picture book biography sheds light on Dr. Salk's groundbreaking journey and the importance of vaccination.
The Polish Climate in the European Context: An Historical Overview
by Jacek Majorowicz Marek Kejan Rajmund Przybylak Rudolf BrázdilReconstruction of the climate variability of the past 500 years is a topic of great scientific interest not only in global terms, but also at regional and local levels. This period is interesting on account of the increasing influence of anthropogenic forcing and its overlap with natural factors. The Polish Climate in the European Context: An Historical Overview summarises the results of research into climate variability based on a combination of instrumental, documentary, dendrochronological and borehole data from Poland. The first part of the book provides a Central European perspective of research in these fields, which forms the general background for a presentation of the state of the art of climatic change studies in Poland during the past 500 years (Part 2). This is followed by a selection of papers dealing mainly with different aspects of climate variability in Poland and Central Europe (Part 3). "This book is a valuable tool integrating Polish, Central and Eastern European climate research into the global context. It is, as such, a must for climate researchers worldwide." (Gaston Demarée, Royal Meteorological Institute of Belgium) "This volume marks a significant step forward in our understanding of European climatic history." (Christian Pfister, University of Bern)
Polish River Basins and Lakes – Part I: Hydrology and Hydrochemistry (The Handbook of Environmental Chemistry #86)
by Ewa Korzeniewska Monika HarniszThis book offers a comprehensive review of the current environmental conditions and chemical changes in Polish surface waters. Poland is situated in an area that was covered by glaciations in the distant past. The subsequent periods of glacial advance and retreat produced a continuous rejuvenation of the landscape, and the discharge of surplus water from this area was constantly transformed by morphological, climatic and hydrological changes. Written by expert contributors, the book’s respective chapters address the impact of current climatic conditions on the functioning of surface water reservoirs in Poland, while also exploring the country’s hydrographic and hydrological network and the trophic state of its rivers and lakes, their eutrophication and threats. Particular attention is paid to sources of pollution, above all, the chemical pollution of water and sediments. Together with the companion book Polish River Basins and Lakes – Part II: Biological Status and Water Management, it provides students, environmental chemists, biologists, geologists, hydrologists and surface waters managers with authoritative information on Poland’s current environmental status.
Political Agroecology: Advancing the Transition to Sustainable Food Systems (Advances in Agroecology)
by Manuel González de Molina Paulo Frederico Petersen Francisco Garrido Peña Francisco Roberto CaporalPolitical Agroecology is the first book to offer a systematic and articulated reflection on Political Agroecology from the Agroecological perspective. It defines the disciplinary field responsible for designing and producing actions, institutions and regulations aimed at achieving agrarian sustainability. In short, it aims to build a political theory that makes the scaling-up of agroecological experiences possible, turning them into the foundation of a new and alternative food regime. The book proposes theoretical, practical and epistemological foundations of a new theoretical and practical field of work for agroecologists: Political Agroecology. It establishes a framework for a common agroecological strategy, covering the different levels of collective action and the different instruments with which it can be developed. This will be essential reading for agroecologists, environmentalists, farming and food communities, and an ideal textbook for advanced agroecology courses in universities. Key features: Offers a unique state of the art on this fundamental new topic: Political Agroecology Presents a complete introduction to the political and institutional aspects of Agroecology, covering the whole food system Offers an important tool for searching agrarian sustainability Provides a broad epistemological, theoretical and methodological focus, exploring the connection between the different levels and scales involved in agroecological theory and practice
Political Biology: Science and Social Values in Human Heredity from Eugenics to Epigenetics
by M. MeloniThis book explores the socio-political implications of human heredity from the second half of the nineteenth century to the present postgenomic moment. It addresses three main phases in the politicization of heredity: the peak of radical eugenics (1900-1945), characterized by an aggressive ethos of supporting the transformation of human society via biological knowledge; the repositioning, after 1945, of biological thinking into a liberal-democratic, human rights framework; and the present postgenomic crisis in which the genome can no longer be understood as insulated from environmental signals. In Political Biology, Maurizio Meloni argues that thanks to the ascendancy of epigenetics we may be witnessing a return to soft heredity - the idea that these signals can cause changes in biology that are themselves transferable to succeeding generations. This book will be of great interest to scholars across science and technology studies, the philosophy and history of science, and political and social theory.
Political Biology: Science and Social Values in Human Heredity from Eugenics to Epigenetics
by Maurizio MeloniPolitical Biology.
Political Deference in a Democratic Age: British Politics and the Constitution from the Eighteenth Century to Brexit
by Catherine MarshallThis book explores the concept of deference as used by historians and political scientists. Often confused and judged to be outdated, it shows how deference remains central to understanding British politics to the present day. This study aims to make sense of how political deference has functioned in different periods and how it has played a crucial role in legitimising British politics. It shows how deference sustained what are essentially English institutions, those which dominated the Union well into the second half of the twentieth century until the post-1997 constitutional transformations under New Labour. While many dismiss political and institutional deference as having died out, this book argues that a number of recent political decisions – including the vote in favour of Brexit in June 2016 – are the result of a deferential way of thinking that has persisted through the democratic changes of the twentieth century. Combining close readings of theoretical texts with analyses of specific legal changes and historical events, the book charts the development of deference from the eighteenth century through to the present day. Rather than offering a comprehensive history of deference, it picks out key moments that show the changing nature of deference, both as a concept and as a political force.
Political Descent: Malthus, Mutualism, and the Politics of Evolution in Victorian England
by Piers J. HaleHistorians of science have long noted the influence of the nineteenth-century political economist Thomas Robert Malthus on Charles Darwin. In a bold move, Piers J. Hale contends that this focus on Malthus and his effect on Darwin’s evolutionary thought neglects a strong anti-Malthusian tradition in English intellectual life, one that not only predated the 1859 publication of the Origin of Species but also persisted throughout the Victorian period until World War I. Political Descent reveals that two evolutionary and political traditions developed in England in the wake of the 1832 Reform Act: one Malthusian, the other decidedly anti-Malthusian and owing much to the ideas of the French naturalist Jean Baptiste Lamarck. These two traditions, Hale shows, developed in a context of mutual hostility, debate, and refutation. Participants disagreed not only about evolutionary processes but also on broader questions regarding the kind of creature our evolution had made us and in what kind of society we ought therefore to live. Significantly, and in spite of Darwin’s acknowledgement that natural selection was "the doctrine of Malthus, applied to the whole animal and vegetable kingdoms,” both sides of the debate claimed to be the more correctly "Darwinian. ” By exploring the full spectrum of scientific and political issues at stake, Political Descent offers a novel approach to the relationship between evolution and political thought in the Victorian and Edwardian eras.
Political Ecology: A Critical Engagement with Global Environmental Issues
by Tor A. Benjaminsen Hanne SvarstadThis textbook introduces political ecology as an interdisciplinary approach to critically examine land and environmental issues. Drawing on discourse and narrative analysis, Marxist political economy and insights from natural science, the book points at similarities, differences and inter-connections between environmental governance in the global North and South. A wide range of carefully curated case studies are presented, with a particular focus on Africa and Norway. Key themes of power, justice and environmental sustainability run through all chapters. The authors challenge established views and leading discourses and present research findings that may surprise readers. Chapters cover topics including wildlife conservation, climate change and conflicts, land grabbing, the effects of population growth on the environment, jihadism in the African Sahel, bioprospecting, feminist political ecology, and struggles around carbon mitigation within a fossil fuel-based economy. This introductory text provides tools and examples for both undergraduate and postgraduate students to better understand on-going struggles about some of the world’s most urgent challenges.
Political Ecology: Deconstructing Capital and Territorializing Life
by Enrique LeffThis book offers a conceptual framework for the critical understanding of the present socio-environmental conflicts. It reflects on the evolution of subject and thought, a shift in environmental thinking triggered by the development of eco-territorial conflicts and the social responses given to the environmental question. Bringing together 40 years of the authors writing and research, the book explores the transition from ecological economics and historical materialism to ecological Marxism. It unpacks the forging of political ecology from value theory in political economy, to ecological distribution and ecologies of difference; a transition to an environmental rationality grounded in the ontology of diversity, a politics of difference and an ethics of otherness. This evolution in thinking gives consistency to a theoretical discourse able to respond to the territorial conflicts generated by the radicalization of the environmental question as a key social issue of our times. The book is a call to respond to the urgent challenge of reversing the tendency towards the entropic death of the planet and to building a sustainable world order.
Political Ecology
by Paul RobbinsThis fully updated new edition introduces the core concepts, central thinkers, and major works of the burgeoning field of political ecology.Explores the key arguments and contemporary explanatory challenges facing the sub-disciplineProvides the first full history of the development of political ecology over the last century and its theoretical underpinningsConsiders the major challenges facing the field now and for the futureStudy boxes introduce key figures in the development of the discipline and summarize their most important worksFully updated to include recent events, such as the Gulf of Mexico Oil Spill, as well as both urban and rural examples, from the developed and underdeveloped world
Political Ecology
by Karl Zimmerer Thomas J. BassettThis volume offers a unique, integrative perspective on the political and ecological processes shaping landscapes and resource use across the global North and South. Twelve carefully selected case studies demonstrate how contemporary geographical theories and methods can contribute to understanding key environment-and-development issues and working toward effective policies. Topics addressed include water and biodiversity resources, urban and national resource planning, scientific concepts of resource management, and ideas of nature and conservation in the context of globalization. Giving particular attention to evolving conceptions of nature-society interaction and geographical scale, an introduction and conclusion by the editors provide a clear analytical focus for the volume and summarize important developments and debates in the field.
A Political Ecology of Forest Conservation in India: Communities, Wildlife and the State (Routledge Studies in Conservation and the Environment)
by Amrita SenThis book critically explores the political ecology of human marginalization, wildlife conservation and the role of the state in politicizing conservation frameworks, drawing on examples from forests in India. The book specifically demonstrates the nuances within human-environmental linkages, by showing how environmental concerns are not only ecological in content but also political. In India a large part of the forests and their surrounding areas were inhabited far before they were designated as protected areas and inviolate zones, with the local population reliant on forests for their survival and livelihoods. Thus, socioecological conflicts between the forest dependents and official state bodies have been widespread. This book uses a political ecology lens to explore the complex interplay between current norms of forest conservation and environmental subjectivities, illustrating contemporary articulation of forest rights and the complex mediations between forest dependents and different state and non-state bodies in designing and implementing regulatory standards for wildlife and forest protection. It foregrounds the issues of identity, migration and cultural politics while discussing the politics of conservation. Through a political ecology approach, the book not only is human-centric but also makes significant use of the role of non-humans in foregrounding the conservation discourse, with a particular focus on tigers. The book will be of great interest to students and academics studying forest conservation, human–wildlife interactions and political ecology.
Political Ecology of Industrial Crops (Earthscan Food and Agriculture)
by Abubakari AhmedThis book employs a political ecology lens to unravel how industrial crops catalyse ecological, agrarian, socioeconomic, and institutional transformation. Using the conceptual tools and perspectives of political ecology, namely multi-scalar analysis and attention to marginalisation, social difference, and discourses and narratives, this volume provides a critical and comprehensive assessment of the transformative power of industrial cropping systems. It presents a truly international overview by drawing on a range of case studies from the global South, including soybeans in South America, cashew nuts in Guinea Bissau, cotton in India, maize in China, jatropha in Ghana, sugarcane in Peru and Eswatini, and oil palm in Ghana and Peru. The unique case studies are put into perspective with chapters introducing the key concepts of political ecology and critical dimensions of industrial cropping systems related to large-scale land acquisitions, land grabbing, and marginal land. The individual chapters employ different approaches all rooted in political ecology, thus offering a rich overview of how the field engages with such cropping systems. Overall, this volume contains valuable propositions for improving current policies and practices in industrial crop settings in both developed and developing countries. Through its comprehensive and interdisciplinary outlook, this volume will be of great interest to students and scholars of political ecology, agrarian studies, development studies, and ecological economics.
Political Economy and International Order in Interwar Europe (Palgrave Studies in the History of Economic Thought)
by Alexandre M. Cunha Carlos Eduardo SuprinyakStandard histories of European integration emphasize the immediate aftermath of World War II as the moment when the seeds of the European Union were first sown. However, the interwar years witnessed a flurry of concern with the reconstruction of the world order, generating arguments that cut across the different social sciences, then plunged in a period of disciplinary soul-searching and feverish activism. Economics was no exception: several of the most prominent interwar economists, such as F. A. Hayek, Jan Tinbergen, Lionel Robbins, François Perroux, J. M. Keynes and Robert Triffin, contributed directly to larger public discussions on peace, order and stability. This edited volume combines these different strands of historical narrative into a unified framework, showing how political economy was integral to the interwar literature on international relations and, conversely, how economists were eager to incorporate international politics into their own concerns. The book brings together a group of scholars with varied disciplinary backgrounds, whose combined perspectives allow us to explore three analytical layers. The first part studies how different forms of economic knowledge, from economic programming to international finance, were used in the quest for a stable European order. The second part focuses on the existence of conflicting expectations about the role of social scientific knowledge, either as a source of technical solutions or as an input for enlightened public discussion. The third part illustrates how certain ideas and beliefs found concrete expression in specific institutional settings, which amplified their political leverage. The three parts are enclosed by an introductory essay, laying out the broad topics explored in the volume, and a substantial postscript tying all the historical threads together.
The Political Economy Of Agricultural Trade And Policy: Toward A New Order For Europe And North America
by Hans J Michelmann Jack C Stabler Gary StoreyThis book presents a descriptive analysis of the political economy of the European Community, the U.S. and Canada. It describes the structural changes and the crises in agriculture and focuses on impact of GATT on agricultural policy and trade in the post-Second World War era.
Political Economy of China’s Climate Policy (Research Series on the Chinese Dream and China’s Development Path)
by Jiahua PanThis book covers major advances in China’s climate policy over the past decade and presents theoretical approaches to climate justice and low-carbon transformation from a Chinese perspective. It analyzes the political economy of China’s climate policy, and subsequently addresses the following major aspects: carbon emissions and human rights, equity and carbon budgets, economic analysis of low-carbon transformation, economics of adaptation to climate change, and international climate regime building.
The Political Economy of Climate Change Adaptation
by Benjamin K. Sovacool Björn-Ola LinnérDrawing on concepts in political economy, political ecology, justice theory, and critical development studies, the authors offer the first comprehensive, systematic exploration of the ways in which adaptation projects can produce unintended, undesirable results.This work is on the Global Policy: Next Generation list of six key books for understanding the politics of global climate change.
The Political Economy of Coal: Obstacles to Clean Energy Transitions (Environment for Development)
by Michael JakobThis volume provides an overview of the political economy of coal in diverse country contexts. Coal is the largest source of greenhouse gas emissions globally, accounting for about 40 percent of energy-related CO2 emissions. Continued construction of coal-fired power plants could make the climate targets of the Paris Agreement infeasible to achieve. In spite of sharply declining costs for renewable energy sources, many countries still heavily rely on coal to meet their energy demand. The predominance of coal can only be adequately understood in light of the political factors that determine energy policy formulation. To this end, this edited volume assembles a wide variety of case studies exploring the political economy of coal for across the globe. These includes industrial and developing nations, coal importers and exporters as well as countries that are either substantial coal users, are just beginning to ramp up their capacities, or have already initiated a coal phase-out. Importantly, all case studies are structured along a unifying framework that focuses on the central actors driving energy policy formulation, their main objectives as well as the context that determines to what extent they can influence policy making. This large set of comparable studies will permit drawing conclusions regarding key similarities as well as differences driving coal use in different countries. This book will be of great interest to students and scholars of energy, climate change, resource management, and sustainable development. It will also appeal to practitioners and policymakers involved in sustainable development.