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Polyamines

by Robert A. Casero Jr. Anthony E. Pegg

Recently, important new findings in the polyamine field and a variety of new experimental systems have revolutionized the study of these ubiquitous cellular components, essential for normal growth and development. In Polyamines: Methods and Protocols, leading researchers contribute an extensive collection of up-to-date laboratory techniques for the further pursuit of polyamine study. The volume delves into vital subjects such as neoplasia studies with animal models and human patients, therapeutic roles for polyamine inhibitors and analogs, polyamine metabolism and oxidative damage, polyamines as regulators of critical ion channels, as well as polyamine transport systems and polyamine-responsive genes. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and expert notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Polyamines: Methods and Protocols provides a key resource for all scientists pursuing the study of this dynamic and significant aspect of cellular biology.

Polyamines

by Tomonobu Kusano Hideyuki Suzuki

This book covers key topics in polyamine research from a range of organisms, including plants, mammals, and prokaryotes such as bacteria and archaea. The book provides an introduction to general concepts in the field of polyamine research, as well as more detailed information. With the availability of genome sequence data from a broad range of organisms, the evolution of the genes involved in polyamine metabolism is discussed. The mode of action of polyamines has been shown to be dependent on cation channels, and this mechanism is described in the book. The origin of polyamine transporters (from bacteria, yeasts, and plants) is described. The various effects of polyamines on growth and survival are also documented. The book details the mechanisms of polyamine homeostasis and the role of polyamine molecules as precursors of secondary metabolites such as plant alkaloids and toxins derived from spiders and wasps. The role of polyamines in longevity and disease is discussed. A link between polyamine contents and cancer progression is reported, as is the use of polyamine metabolites as diagnostic markers in the initial stages of cancer. Moreover, a novel approach that utilizes the polyamine pathway of a parasite as a drug target in African sleeping sickness is described. Therefore, this book is a valuable resource, both as a textbook for undergraduate and graduate students and also as a reference book for front-line polyamine researchers.

Polyamines in Fungi: Their Distribution, Metabolism, and Role in Cell Differentiation and Morphogenesis

by Laura Valdes-Santiago José Ruiz-Herrera

It was not until recent years that the study of polyamines, their mechanisms of synthesis, and the roles they play in metabolism have flourished, becoming a fertile field of intense research. Polyamines in Fungi: Their Distribution, Metabolism, and Role in Cell Differentiation and Morphogenesis provides a complete overview of its topic. It is the f

Polyampholytes in Advanced Polymer Science and Emerging Technologies (Emerging Materials and Technologies)

by Sarkyt E. Kudaibergenov

Polyampholytes are unique polymers containing acid/base and/or anionic/cationic groups in the main or side chains. Water-soluble and water-swelling polyampholytes exhibit properties that provide broad potential as structural biomaterials, drug delivery and chemo-mechanical systems, biosensors, energy storage devices, supercapacitors, and actuators, among others. This monograph reviews the innovative studies in this field over the past two decades, with the aim to analyze and systematize the literature in the context of emerging technologies. Offers a multidisciplinary perspective covering polyampholytes, polybetaines, and polyzwitterions in nanotechnology, biotechnology, medicine, catalysis, environment protection, and oil industry applications Demonstrates a wide range of applications for these materials with enough depth to provide critical fundamental knowledge for new researchers in the field Discusses polyampholyte-protected and gel-immobilized metal nanoparticles and enzymes that catalyze reactions of hydrolysis, decomposition, hydrogenation, and oxidation of various substrates in batch-type and continuous flow–type reactors Highlights the remaining persistent challenges in the development and application of these materials This book will appeal to readers who conduct materials research for biomedical, water treatment, and environmental remediation applications.

Polyarenes II

by Yao-Ting Wu Jay S. Siegel

Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.

Polybutilene Therephthalate (PBT), Synthesis and Properties

by M.A. Mikitaev T.A. Borukaev

This volume gives an analysis of recent achievements in the field of synthesis, structural investigations, and properties of polybutilene therephthalate (PBT). Furthermore, the mechanism of PBT synthesis by equilibrium polycondensation reaction is described together with the used reagents, catalysts, and stabilizers.

Polycomb Group Proteins

by Chiara Lanzuolo Beatrice Bodega

This volume presents the most recent technologies used in the Polycomb Group Proteins (PcG) field. Chapters detail state-of-the-art methods, creating a unique and comprehensive reference source for investigating Polycomb function in the nucleus. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Polycomb Group Proteins: Method and Protocols aims to ensure successful results in the further study of this vital field.

Polycomb Group Proteins: Methods and Protocols (Methods in Molecular Biology #2655)

by Chiara Lanzuolo Federica Marasca

This volume explores the latest technologies used in the Polycomb Group of proteins field and helps scientists--working on PcG proteins--investigate all functions of PcG proteins in diverse cellular contexts. The chapters in this book cover topics such the distribution of histone marks by CUT&Tag in Drosophila embryos; Co-IP in mammalian cells; replication timing of gene loci in different cell cycle phases; STORM and electronmicroscopy and relative data analysis; and polycomb mediated epigenetic modification in spheroids. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Polycomb Group Proteins: Methods and Protocols, Second Edition is a valuable tool for all researchers looking to expand their knowledge of this developing field.

Polycondensation

by Hans Kricheldorf

This book reports on origin and history of polycondensation chemistry beginning in the first half of the 19th century. Furthermore, history and inventors of the most important polycondensates, such as Nylons, PET or polycarbonates, are described. The classical theory of step-growth polymerizations is discussed in the light of the latest experimental and theoretical results. Particular emphasis is laid on the role of cyclization reactions. Special categories of polycondensation processes are discussed in more detail: syntheses of hyperbranched and multicyclic polymers, non-stoichiometric polycondensations, interfacial polycondensations, solid state polycondensations, condensative chain polymerizations etc.

Polycyclic Arenes and Heteroarenes

by Qian Miao

The first book of its kind to focus on the chemistry of this promising class of molecules. Edited by an innovator in the field, who has gathered an international team of well-established experts, this is a comprehensive overview of the rapidly developing field of polycyclic (hetero)arenes, specifically highlighting on their molecular design and the latest synthetic procedures, as well as chemical and physical properties. Each chapter is dedicated to a specific compound class, the first eight covering polycyclic arenes, including both planar and non-planar conjugated molecules, while chapters nine to twelve deal with polycylic heteroarenes according to the heteroatoms, namely N, B, S and P. Important current and emergent applications in the field are also discussed, ranging from molecular sensors to electronic devices. The result is an essential reference for researchers in synthetic and physical organic chemistry, supramolecular chemistry, and materials science.

Polycyclic Aromatic Hydrocarbons: Environmental Behavior and Toxicity in East Asia

by Kazuichi Hayakawa

This book reviews Polycyclic Aromatic Hydrocarbons (PAHs) and Nitropolycyclic Aromatic Hydrocarbons (NPAHs) contamination in the context of environmental pollution in Asia. It is comprised of the following sections: 1. Fundamental Chemistry and General Characteristics; 2. Analytical Methods; 3. Emission Source and Atmospheric Behavior; 4. Atmospheric Polycyclic Aromatic Hydrocarbons and PM2.5; 5. Polycyclic Aromatic Hydrocarbons in Marine Environments; 6. Metabolic Activation/Toxicities; and 7. Environmental Standards and Guidelines. This volume concentrates on the Far East due to the massive consumption of coal and petroleum in China, which has led to considerable levels of air pollution. High concentration of atmospheric PM2.5 in Beijing have been reported since January 2013 and exposure to such high concentrations may cause respiratory, cardiac and lung diseases. Gathering contributions from international experts, this volume provides a valuable reference guide for global researchers and students interested in learning from the East Asian experience.

Polycyclic Aromatic Hydrocarbons

by Huizhong Shen

This thesis presents a comprehensive analysis of the globalhealth impacts of polycyclic aromatic hydrocarbons (PAHs) in ambient air,conducted on the basis of a high-resolution emission inventory, global chemicaltransport modeling, and probabilistic risk assessment. One of the mainstrengths of the thesis is the concentration downscaling process, whichprovides a linkage between emissions and exposure concentrations at acomparatively high resolution. Moreover, by focusing on individual susceptibility,the thesis proposes an instrumental revision of current risk assessmentmethodology and argues that, if individual susceptibility were not taken intoconsideration, the overall risk would be underestimated by 55% and theproportion of highly vulnerable populations would be underestimated by morethan 90%.

Polycystic Kidney Disease (Methods in Signal Transduction Series)

by Jinghua Hu Yong Yu

This volume focuses on the investigatory methods applied to autosomal dominant polycystic kidney disease (ADPKD), one of the most common human genetic diseases. ADPKD is caused by mutations in PKD1 and TRPP2, two integral membrane proteins that function as receptor/ion channels in primary cilia of tubular epithelial cells. Thus, ADPKD belongs to ciliopathies, a group of disorders caused by abnormal cilia formation or function. This proposed book will cover the state-of-the-art methods ranging from molecular biology, biochemistry, electrophysiology, to tools in model animal studies. Key Features Explores the role of cilia in polycystic kidney disease Focuses on myriad state-of-the-art methods and techniques Reviews specific mutations integral to this autosomal genetic disease Includes discussions of model systems

Polyelectrolytes

by Visakh P. M. Oguz Bayraktar Guillermo Alfredo Picó

This book offers a valuable reference source to graduate and post graduate students, engineering students, research scholars polymer engineers from industry. The book provides the reader with current developments of theoretical models describing the thermodynamics polyelectrolytes as well as experimental findings. A particular emphasis is put on the rheological description of polyelectrolyte solutions and hydrogels.

Polyembryonic Insects: An Extreme Clonal Reproductive Strategy (Entomology Monographs)

by Kikuo Iwabuchi

This book provides an overview of our current understanding of polyembryony in insects. The study of polyembronic insects has advanced considerably over the last several decades.The book shows the exciting potential of polyembryonic insects and their impact on life sciences. It describes the mechanisms of polyembryogenesis; tissue-compatible invasion of the host, which is the first case of compatible cellular interaction between phylogenetically distant organisms without rejection; the sex differences in defense; and the environmental regulation of caste structure. The first book devoted to polyembryony in insects, it draws on the author’s research on polyembryonic wasps from 1990 to the present day, covering various topics such as polyembryogenesis in vitro, host-parasite interaction, sex differences in soldier function/humoral toxic factor, and the transcription analysis of polyembryogenesis.It is intended not only for researchers in the field of entomology, parasitology, ontogeny, reproductive biology, developmental biology, sociobiology, and evolutionary developmental biology (Evo-Devo), but also for postgraduate students in these fields.

Polyester Films: Materials, Processes and Applications

by Miko Cakmak Jehuda Greener

This volume presents a comprehensive review of key aspects of polyester film technology, ranging from first principles to practical applications Bringing together world-class experts to review the state-of-the-art of key materials and processing elements of polyester film technology, Polyester Films covers a wide range of topics with direct utility to students, practitioners, business managers and researchers, in academia and industry. Topics covered in this volume include survey of optical and physical properties, microlayer coextrusion, polyester ionomers, polyester blends, biomedical applications and recycling . In particular, the text focuses on novel design and application of polyester films, such as those used in the production of flat panel displays, flexible electronics, and barrier films. The overriding objective of the book is to scope the multitude of options available to material and product designers in manipulating the properties of polyester films to meet specific performance and product criteria. These options include synthetic modifications (copolymerization), physical enhancements (blending), and process upgrades (tenter-frame changes, coextrusion, and coating). Edited by two highly qualified material scientists with extensive experience in academia and industry, Polyester Films covers topics such as: Historical review of polyester film technology Overview of physical performance and applications of key polyester films, especially PET and PEN Synthetic options available for manipulating the structure and properties of polyesters, with special focus on polyester ionomers Main blending options available to enhance the performance of commodity polyesters Rheo-optical properties of polyester films and corresponding testing methodology Micro-layer coextrusion technology as applied to modify the performance of polyester films Bio-medical applications Polyester recycling, with special focus on upcyclingWith an interdisciplinary approach covering the performance of real-life products and components, Polyester Films is an essential resource for researchers and engineers in academia and industry working in physics, material science, chemistry and process engineering. This volume should also be invaluable for graduate students and early-career researchers in similar fields.

Polyether Antibiotics: Naturally Occurring Acid Ionophores--Volume 2: Chemistry

by J. W. Westley

This collection of essays will stimulate the use of ionophores in different research areas. It includes information on potential breakthroughs in the halogenated derivatives of lasalocid and ethers of antibiotic A204A, polyethers and analytical techniques used to unravel their complex structures.

Polyethylene-Based Biocomposites and Bionanocomposites (Thermoplastic Bionanocomposites Series)

by Visakh. P. M. Sigrid Lüftl

Biodegradable polymers have experienced a growing interest in recent years for applications in packaging, agriculture, automotive, medicine, and other areas. One of the drivers for this development is the great quantity of synthetic plastic discarded improperly in the environment. Therefore, R&D in industry and in academic research centers, search for materials that are reprocessable and biodegradable. This unique book comprises 12 chapters written by subject specialists and is a state-of-the-art look at all types of polyethylene-based biocomposites and bionanocomposites. It includes deep discussion on the preparation, characterisation and applications of composites and nanocomposites of polyethylene-based biomaterials such as cellulose, chitin, starch, soy protein, PLA, casein, hemicellulose, PHA and bacterial cellulose.

Polyethylene-Based Blends, Composites and Nanocomposities

by Visakh P. M. María José Morlanes

The book focusses on the recent technical research accomplishments in the area of polyethylene-based blends, composites and nanocomposites by looking at the various aspects of processing, morphology, properties and applications. <P><P> In particular, the book details the important developments in areas such as the structure-properties relationship of polyethylene; modification of polyethylene with radiation and ion implantation processes; stabilization of irradiated polyethylene by the introduction of antioxidants; reinforcement of polyethylene through carbon-based materials as additives; characterization of carbon-based polyethylenes composites, polyethylene-based blends with thermoplastic and thermoset; characterization of polyethylene-based thermoplastic and thermoset blends; polyethylene-based blends with natural rubber and synthetic rubber; characterization of polyethylene-based natural rubber and synthetic rubber blends; characterization of polyethylene-based composites.

Polyextremophiles: Life Under Multiple Forms of Stress

by Aharon Oren Helga Stan-Lotter Joseph Seckbach

Many Microorganisms and some macro-organisms can live under extreme conditions. For example, high and low temperature, acidic and alkaline conditions, high salt areas, high pressure, toxic compounds, high level of ionizing radiation, anoxia and absence of light, etc. Many organisms inhabit environments characterized by more than one form of stress (Polyextremophiles). Among them are those who live in hypersaline and alkaline, hot and acidic, cold/hot and high hydrostatic pressure, etc. Polyextremophiles found in desert regions have to copy with intense UV irradiation and desiccation, high as well as low temperatures, and low availability of water and nutrients. This book provides novel results of application to polyextremophiles research ranging from nanotechnology to synthetic biology to the origin of life and beyond.

Polyfluorinated Chemicals and Transformation Products

by Thomas P. Knepper Frank T. Lange

Due to their unparalleled effectiveness and efficiency, polyfluorinated chemicals (PFC) have become essential in numerous technical applications. However, many PFCs brought to market show limited biodegradability, and their environmental persistence combined with toxic and bioaccumulative potential have become a matter of concern in some instances. This volume highlights the synthesis of PFCs, focusing on substances with improved application and environmental properties, which are a challenge for synthetic chemists. Further, modern mass spectrometric techniques for the detection and identification of biotransformation products of PFCs are described. The sorption and leaching behavior of PFC in soil is also addressed in order to predict their fate in the environment. Several contributions discuss the monitoring of PFCs in European surface, ground and drinking waters, treatment options for PFC removal from drinking water, occurrence in food, and the human biomonitoring of PFCs.

Polyhydroxyalkanoates: Microbial Biodiversity, Biowastes, and Bioprocesses

by Vipin Chandra Kalia

This book highlights microbial biodiversity, biowastes, and innovative bioprocesses that contribute to creating these environmentally friendly biopolymers. The chapters discuss key concepts such as the occurrence and biosynthesis of natural and synthetic biopolymer composites, recent advances in using engineered E. coli and Pseudomonas as microbial factories revolutionizing biopolymer production, and the challenges and opportunities presented by cyanobacterial PHA research. Additionally, it investigates green synthesis methods that convert lignocellulosic biomass into PHAs and examines various feedstocks like sugar- and starch-rich waste for fermentation substrates. Researchers in biotechnology, environmental science, materials engineering, and related fields will find this book indispensable. It offers a comprehensive overview of current R&D activities to achieve sustainable PHA production. The book provides both theoretical perspectives and practical case studies, offers a wealth of knowledge to guide readers’ exploration of biopolymer production, making it a must-read for anyone dedicated to advancing eco-friendly materials science.

Polyhydroxyalkanoates: Agriculture, Industry, and Environment

by Vipin Chandra Kalia

This book overviews the sustainable production and diverse applications of Polyhydroxyalkanoates (PHAs), with a special focus on agriculture, industry, and the environment. It provides a comprehensive overview of the latest strategies to overcome production challenges and enhance commercial feasibility. By exploring the potential of cost-effective raw materials and genetically engineered microbes, this volume highlights innovative approaches to ferment biowastes efficiently. The book also examines how blending different PHAs and modifying their chemical structures can expand their applications, making it a must-read for those interested in biotechnological advancements. Key concepts covered include the development of biosensors, bio-indicators, and biofuels, as well as the role of biopolymers in environmental bioremediation. The chapters are organized to provide insights into technological bioprocesses that can be translated into globally competitive business proposals. Readers will discover contributions from renowned scholars who probe critical questions about sustainable PHA production and its applications in various industries. This book is essential for researchers, scholars, and practitioners in biotechnology, environmental science, and agricultural engineering. It offers valuable information for those looking to develop eco-friendly solutions and sustainable business models. Whether you are an academic or a professional in the field, this volume provides the latest research and practical insights to help you stay ahead in the rapidly evolving landscape of biopolymers.

Polyhydroxyalkanoates: Biomedical Sector

by Vipin Chandra Kalia

This book provides an in-depth analysis of recent developments in microbial diversity, molecular biology, and biotechnology related to PHA production. PHAs are highlighted as unique biopolymers that are biocompatible, bioresorbable, biodegradable, versatile, and sustainable—qualities that make them strong contenders for various biomedical applications. The chapters cover essential topics such as microbial production of PHAs from biowastes, co-digestion processes to enhance their physio-chemical properties, and challenges related to regulatory approvals and commercialization. Readers will learn about the diverse range of medical applications for PHAs including tissue engineering scaffolds, drug delivery systems, implants, anti-osteoporosis treatments, and memory enhancers. The book also addresses how these biopolymers can be fine-tuned for specific medical uses through advanced bioengineering techniques. Particular attention is given to the potential translation of these technologies into globally competitive business ventures. The volume provides expert analyses on how governmental funding agencies can identify prospective scientific R&D areas. For society at large, this book offers novel concepts about the eco-friendly and economic benefits of PHAs. Researchers in biotechnology, molecular biology, biomedical engineering, and related fields will find this book indispensable. This volume is part of a series dedicated to exploring the vast potential of bioplastics across various sectors. It serves as an essential guide for researchers aiming to achieve sustainable polyhydroxyalkanoate production while addressing critical questions about their practical applications in medicine.

Polyhydroxyalkanoates Biopolymers: Production Strategies (SpringerBriefs in Molecular Science)

by Geeta Gahlawat

This book focuses on both production and extraction aspects of Polyhydroxyalkanoates (PHAs) for their commercialization purpose. PHAs have broad range of applications in packaging, food, agriculture and pharmaceutical industries. Until now literature reports have discussed either production strategies or extraction protocols. But for commercialization purpose both issues need to be addressed. This book highlights other copolymers of PHAs which have much better physico-mechanical properties such as elasticity and strength than polyhydroxybutyrate (PHB). Finally efficient product recovery protocols and process optimization strategies including renewable substrates, high cell density cultivations, genetic engineering and mathematical modeling are discussed in detail in order to outline the progress made so far in the area of economic biopolymer production. The primary audience will be scholars, researchers and professors working in colleges, universities, research institutes and government organizations.

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