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Radiology of the Chest and Related Conditions
by F W WrightThe book presents a comprehensive overview of the various disease processes affecting the chest and related abnormalities. It discusses biopsy and bronchography, as well as a variety of imaging techniques including radiography, fluoroscopy, tomography, and ultrasound.
Radiology of the Post Surgical Abdomen
by Damian J.M. Tolan John BrittendenA comprehensive description of the most common abdominal operations involving the gastrointestinal tract, pancreas, liver and genitourinary systems, illustrated with artists' drawings and images of normal post operative anatomy. The complications associated with each procedure will be in table format consisting of text alongside imaging examples. There will also be teaching points included. The book will be divided into nine chapters.
The Radiology Technologist's Handbook to Surgical Procedures
by AnthonyC AndersonIn the past several years, the rapid development of sophisticated imaging modalities has made radiology the fastest growing specialty in medicine. It is important for the radiologic technologist to keep pace with technology's advancements. The influx of freestanding outpatient facilities and the demands of insurance companies, HMOs and third party reimbursement have brought about change. Medical facilities have begun to call upon nurses, surgical technicians, and other non-radiologic personnel to assist with patient positioning during surgical procedures requiring imaging-creating a need for a concise, how-to guide to performing surgical procedures. The Radiology Technologist's Handbook to Surgical Procedures provides a quick reference for using fluoroscopic and x-ray equipment during surgical procedures. This book includes detailed descriptions and photographs taken in actual clinical settings.By using this manual as a foundation, the radiologic technologist will be able to master many of the operating room x-ray procedures.
Radiometry in Modern Scientific Experiments
by Pravilov AnatolyThe reader is provided with information about methods of calibration of light sources and photodetectors as well as responsiveness of spectral instruments ranging from near infrared to vacuum UV spectral, 1200 - 100 nm, and radiation intensities of up to several quanta per second in absolute and arbitrary units. The author describes for the first time original methods of measurements they created and draws upon over 40 years of experience in working with light sources and detectors to provide accurate and precise measurements. This book is the first to cover these aspects of radiometry and is divided into seven chapters that examine information about terminology, units, light sources and detectors, methods, including author's original ones, of absolute calibration of detectors, spectral instruments responsiveness, absolute measurements of radiation intensity of photoprocesses, and original methods of their study. Of interest to researchers measuring; luminescence spectra, light intensities from IR to vacuum UV, spectral range in wide-light intensity ranges, calibrate light sources and detectors, absolute or relative quantum yields of photoprocess determination.
Radiomics and Radiogenomics: Technical Basis and Clinical Applications (Imaging in Medical Diagnosis and Therapy)
by Ruijiang Li, Lei Xing, Sandy Napel and Daniel L. RubinRadiomics and Radiogenomics: Technical Basis and Clinical Applications provides a first summary of the overlapping fields of radiomics and radiogenomics, showcasing how they are being used to evaluate disease characteristics and correlate with treatment response and patient prognosis. It explains the fundamental principles, technical bases, and clinical applications with a focus on oncology. The book’s expert authors present computational approaches for extracting imaging features that help to detect and characterize disease tissues for improving diagnosis, prognosis, and evaluation of therapy response. This book is intended for audiences including imaging scientists, medical physicists, as well as medical professionals and specialists such as diagnostic radiologists, radiation oncologists, and medical oncologists. Features Provides a first complete overview of the technical underpinnings and clinical applications of radiomics and radiogenomics Shows how they are improving diagnostic and prognostic decisions with greater efficacy Discusses the image informatics, quantitative imaging, feature extraction, predictive modeling, software tools, and other key areas Covers applications in oncology and beyond, covering all major disease sites in separate chapters Includes an introduction to basic principles and discussion of emerging research directions with a roadmap to clinical translation
Radionanomedicine: Combined Nuclear And Nanomedicine (Biological and Medical Physics, Biomedical Engineering)
by Dong Soo LeeThis book describes radionanomedicine as an integrated medicine using exogenous and endogenous This book describes radionanomedicine as an integrated approach that uses exogenous and endogenous nanomaterials for in vivo and human applications. It comprehensively explains radionanomedicine comprising nuclear and nanomedicine, demonstrating that it is more than radionanodrugs and that radionanomedicine also takes advantage of nuclear medicine using trace technology, in which miniscule amounts of materials and tracer kinetic elucidate in vivo biodistribution. It also discusses exogenous nanomaterials such as inorganic silica, iron oxide, upconversion nanoparticles and quantum dots or organic liposomes labelled with radioisotopes, and radionanomaterials used for targeted delivery and imaging for theranostic purposes. Further, it examines endogenous nanomaterials i.e. extracellular vesicles labelled with radioisotopes, known as radiolabelled extracellular vesicles, as well as positron emission tomography (PET) and single photon emission computed tomography (SPECT), which elucidate the biodistribution and potential for therapeutic success.
Radionuclide Concentrations in Food and the Environment
by Leo M. L. Nollet Michael PoschlAs radiological residue, both naturally occurring and technologically driven, works its way through the ecosystem, we see its negative effects on the human population. Radionuclide Concentrations in Food and the Environment addresses the key issues concerning the relationship between natural and manmade sources of environmental radioactivity
Radionuclide Imaging of Infection and Inflammation: A Pictorial Case-Based Atlas
by Elena Lazzeri Alberto Signore Paola Anna Erba Napoleone Prandini Annibale Versari Giovanni D´Errico Giuliano MarianiThis atlas explores the latest advances in radionuclide imaging in the field of inflammatory diseases and infections, which now typically includes multimodality fusion imaging (e.g. in SPECT/CT and in PET/CT). In addition to describing the pathophysiologic and molecular mechanisms on which the radionuclide imaging of infection/inflammation is based, the clinical relevance and impact of such procedures are demonstrated in a collection of richly illustrated teaching cases, which describe the most commonly observed scintigraphic patterns, as well as anatomic variants and technical pitfalls. Special emphasis is placed on using tomographic multimodality imaging to increase both the sensitivity and specificity of radionuclide imaging.The aim of the second edition of this book is to update the first (published in 2013) by reflecting the changes in this rapidly evolving field. Particular attention is paid to the latest advances in the radionuclide imaging of infection and inflammation, including the expanding role of hybrid imaging with [18F]FDG PET/CT SPECT/CT, without neglecting new radiotracers proposed for the imaging of infection/inflammation. Written by respected experts in the field, the book will be an invaluable tool for residents in nuclear medicine, as well as for other specialists.
Radionuclides in the Environment
by David A. AtwoodNuclear energy is the one energy source that could meet the world's growing energy needs and provide a smooth transition from fossil fuels to renewable energy in the coming decades and centuries. It is becoming abundantly clear that an increase in nuclear energy capacity will, and probably must, take place.However, nuclear energy and the use of radionuclides for civilian and military purposes lead to extremely long-lived waste that is costly and highly problematic to deal with. Therefore, it is critically important ot understand the environmental implications of radionuclides for ecosystems and human health if nuclear energy is to be used to avoid the impending global energy crisis. The present volume of the EIC Books series addresses this critical need by providing fundamental information on environmentally significant radionuclides.The content of this book was developed in collaboration with many of the authors of the chapters. Given the enormity of the subject the Editor and the Authors had to be judicious in selecting the chapters that would appropriately encompass and describe the primary topics, particularly those that are of importance to the health of ecosystems and humans. The resulting chapters were chosen to provide this information in a book of useful and appropriate length. Each chapter provides fundamental information on the chemistry of the radionuclides, their occurrence and movement in the enivornment, separation and analyses, and the technologies needed for their remediation and mitigation. The chapters are structured with a common, systematic format in order to facilitate comparions between elements and groups of elements.About EIC BooksThe Encyclopedia of Inorganic Chemistry (EIC) has proved to be one of the defining standards in inorganic chemistry, and most chemistry libraries around the world have access either to the first of second print editon, or to the online version. Many readers, however, prefer to have more concise thematic volumes, targeted to their specific area of interest. This feedback from EIC readers has encouraged the Editors to plan a series of EIC Books, focusing on topics of current interest. They will appear on a regular basis, and will feature leading scholars in their fields. Like the Encyclopedia, EIC Books aims to provide both the starting research student and the confirmed research worker with a critical distillation of the leading concepts in inorganic and bioinorganic chemistry, and provide a structured entry into the fields covered.This volume is also available as part of Encyclopedia of Inorganic Chemistry, 5 Volume Set.This set combines all volumes published as EIC Books from 2007 to 2010, representing areas of key developments in the field of inorganic chemistry published in the Encyclopedia of Inorganic Chemistry. Find out more.
Radionuclides in the Environment
by Clemens Walther Dharmendra K. GuptaThis book provides extensive and comprehensive information to researchers and academicians who are interested in radionuclide contamination, its sources and environmental impact. It is also useful for graduate and undergraduate students specializing in radioactive-waste disposal and its impact on natural as well as manmade environments. A number of sites are affected by large legacies of waste from the mining and processing of radioactive minerals. Over recent decades, several hundred radioactive isotopes (radioisotopes) of natural elements have been produced artificially, including 90Sr, 137Cs and 131I. Several other anthropogenic radioactive elements have also been produced in large quantities, for example technetium, neptunium, plutonium and americium, although plutonium does occur naturally in trace amounts in uranium ores. The deposition of radionuclides on vegetation and soil, as well as the uptake from polluted aquifers (root uptake or irrigation) are the initial point for their transfer into the terrestrial environment and into food chains. There are two principal deposition processes for the removal of pollutants from the atmosphere: dry deposition is the direct transfer through absorption of gases and particles by natural surfaces, such as vegetation, whereas showery or wet deposition is the transport of a substance from the atmosphere to the ground by snow, hail or rain. Once deposited on any vegetation, radionuclides are removed from plants by the airstre am and rain, either through percolation or by cuticular scratch. The increase in biomass during plant growth does not cause a loss of activity, but it does lead to a decrease in activity concentration due to effective dilution. There is also systemic transport (translocation) of radionuclides within the plant subsequent to foliar uptake, leading the transfer of chemical components to other parts of the plant that have not been contaminated directly.
Radiopharmaceutical Therapy
by Lisa Bodei Jason S. Lewis Brian M. ZeglisThis book covers foundational topics in the emerging field of radiopharmaceutical therapy. It is divided into three sections: fundamentals, deeper dives, and special topics. In the first section, the authors examine the field from a bird’s-eye view, covering topics including the history of radiopharmaceutical therapy, the radiobiology of radiopharmaceutical therapy, and the radiopharmaceutical chemistry of both metallic and non-metallic radionuclides. The second section provides a more in-depth look at specific radiotherapeutics. Chapters include broader discussions of the different platforms for radiopharmaceutical therapy as well as more focused case studies covering individual radiotherapeutics. The third and final section explores a number of areas for further study, including medical physics, artificial intelligence, in vivo pretargeting, theranostic imaging, and the regulatory review process for radiotherapeutics.This book is the first of its kind and is useful for a broad audience of scientists, researchers, physicians, and students across a range of fields, including biochemistry, cancer biology, nuclear medicine, radiology, and radiation oncology.
Radiopharmaceuticals: Chemistry and Pharmacology
by Adrian D. NunnThis timely resource compares single-photon emission tomography (SPECT), used mainly withTechnetium and iodine for routine clinical examinations, and positron emission tomography(PET) , employing short-lived radionuclides of carbon, oxygen, nitrogen, and fluorine in researchinvestigations.Presenting the logic behind why one approach is better than another in various circumstances,Radio pharmaceuticals details the use of radiolabelled substrates in measuring the effect of diseaseand drugs on regional metabolism and receptor concentration/occupancy .. . discusses factorsaffecting the selective retention of small metal complexes by various tissues .. . analyzes the interactionof small exogenous metal complexes with enzymes in vivo and the critical role of stereochemistry. . . explores the use of radio labelled compounds in the study of neuroactive compounds,neurotransmitters, enzyme inhibitors, and substrates in vivo .. . covers the design and pharmacologyof radiolabelled drugs as probes of site of action , selectivity and specificity, and pharmacokineticsin vivo .. . and more.Extensively referenced with over l 050 bibliographic citations, Radiopharmaceuticals is a state-ofthe-art guide for pharmacists; organic, medicinal , and radiopharmaceutical chemists; pharmacokineticists;nuclear medicine physicians and technologists; neurochemists; and governmentregulatory personnel .
Radiopharmaceuticals: Introduction to Drug Evaluation and Dose Estimation
by Ph.D., Lawerence WilliamsNanoengineering, energized by the desire to find specific targeting agents, is leading to dramatic acceleration in novel drug design. However, in this flurry of activity, some issues may be overlooked. This is especially true in the area of determining dosage and evaluating the effects of multiple agents designed to target more than one site of met
Radiopharmaceuticals and Brain Pathophysiology Studied with Pet and Spect: Studied With Pet And Spect (Routledge Revivals)
by M. Diksic Richard C. RebaFirst published in 1991, this book covers three major areas essential to in vivo biochemical studies with PET and SPECT: synthesis of radiopharmaceuticals, biological modeling, and clinical applications. The book emphasizes advances in the synthesis of radiopharmaceuticals used in PET and SPECT studies of brain flow and oxidatative metabolism, in addition to biological modeling. The most widely used 2-deoxyglucose/2-fluorodeoxyglucose models are discussed, as well as models used in the quantitation of brain receptors. Other topics include a possible model for converting 6-[18F] fluorodopa images into the quantitative rate of dopamine synthesis, evaluations of technetium- and iodine-labeled blood flow tracers, and possibilities for using SPECT to measure other pathophysiological variables. This book will be a valuable reference source to students and specialists interested in these in vivo measurements.
Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine
by Richard J. Kowalsky Kara D. WeathermanAs with previous editions of this textbook, Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine, Fourth Edition, provides a comprehensive introduction to radiopharmaceuticals and their applications in nuclear medicine. With the increasing emphasis on PET and the expanding role of theranostics, the nuclear medicine community continues to grow as evidenced by the development of several new radiopharmaceuticals and technologies for diagnostic and therapeutic applications in recent years. The book is intended for use in courses taught in the disciplines of nuclear pharmacy, nuclear medicine technology, and nuclear medicine. The chapter topics are of moderate depth and breadth and are referenced to the primary literature. As such, this textbook has become a useful resource for professional practitioners in these disciplines and for those preparing for specialty board examination.
Radioprotectors: Chemical, Biological, and Clinical Perspectives
by Edward A. Bump Kamal MalakerIt is essential to minimize damage to normal tissues during radiation therapy and many strategies have been employed in finding the best methods for radioprotection. This book integrates chemical, biological, and clinical perspectives on these strategies and developments, providing a comprehensive treatise. It emphasizes new concepts in radioprotection, aiming to inspire further basic science and clinical progress in radioprotector research. Radioprotectors: Chemical, Biological, and Clinical Perspectives includes the following topics:Early research on radioprotectorsWR-2721, an aminothiol prodrug, as a radioprotectorNew results with naturally occurring thiolsNitroxides as effective radioprotectors in vitro and in vivoRadioprotection observed with radical scavengers or antioxidantsBone marrow radioprotection with cytokines and biological modifiersMultiple mechanisms of altering radiation response by eicosanoidsVascular response to radiation and the importance of vascular damage to normal tissue Modifiers of radiation-induced apoptosisSurvey of clinical trials with radioprotectorsRadiation biologists and oncologists, cancer researchers, and toxicologists will benefit from the findings discussed and strategies for future research.
Radiotheranostics - A Primer for Medical Physicists I: Physics, Chemistry, Biology and Clinical Applications (ISSN)
by Cari Borrás Michael G. StabinThis book covers scientific, clinical, and educational aspects of radiotheranostics in cancer control. Setting the framework, the first volume defines radiotheranostics and describes the history of radionuclide therapy and theranostics, and the biology of cancer. It examines the clinical applications of unconjugated radionuclides, such as ¹³¹I and ²²³Ra, and of radionuclide-conjugated cancer-specific vectors: peptides, small molecules, antibodies, and nanoparticles; introduces clinical trials and drug development; and reviews epidemiological studies and the adverse effects of radionuclide therapy – both radiation injuries and chemical toxicity. It presents the chemistry and physics of radionuclide production, discusses radioactivity measurements and traceability, and addresses important instrumentation aspects: calibration, quantitative imaging, and quality control. Volume I concludes with guidance on the education, training, and competence of a radiotheranostic multidisciplinary team and summarizes the principal physics characteristics of theranostics today – including many to be expanded in the second volume – while offering a glimpse into tomorrow. This volume provides the foundations for the more advanced second volume, which explores dosimetric and radiation safety, aiming to empower medical physicists and demonstrate to the cancer community how to improve cancer control and yield increased patient survival times.It will be a valuable reference for medical and health physicists with basic knowledge of nuclear medicine.Key Features• Provides a comprehensive introduction to the topic, presenting readers with thorough treatment in a cohesive two-volume book.• Presents a rigorous approach while remaining accessible to students and trainees in the field.• Contains consistent and extensive references to allow readers to delve deeper into the subject.
Radiotherapy and Clinical Radiobiology of Head and Neck Cancer (Series in Medical Physics and Biomedical Engineering)
by Loredana G. Marcu Iuliana Toma-Dasu Alexandru Dasu Claes MerckeCommon factors that lead to treatment failure in head and neck cancer are the lack of tumour oxygenation, the accelerated division of cancer cells during treatment, and radioresistance. These tumour-related challenges and possible ways to overcome them are covered in this book, authored by three medical physicists and a clinical oncologist who explain how different radiobiological findings have led to the development of various treatment techniques for head and neck cancer. <P><P>Novel treatment techniques as supported by current scientific evidence are comprehensively explored, as well as the major challenges that arise in the retreatment of patients who have already undergone a form of radiotherapy for primary head and neck cancer. <P><P>Features: <li>Uses an interdisciplinary approach, encompassing clinical aspects of radiotherapy, radiation biology, and medical physics <li>Applies content by relating all radiobiological characteristics to their respective clinical implications <li>Explains the radiobiological rationale for all previous and current clinical trials for head and neck cancer
Radiotherapy in Skin Cancer: A Practical Guide on Indications and Techniques
by Kurian Jones Joseph Michael J. Veness Elizabeth Barnes Agata RembielakRadiotherapy is one of the major treatment modalities utilised for the management of patients diagnosed with skin cancer. This book describes the indications and the various radiotherapy techniques used to treat skin cancer. The technical details of radiotherapy are well addressed and serve as a practical reference to those clinicians involved in managing these patients. The authors are all leading radiation oncologists from the major cancer centers in the USA, Canada, UK & Australia. Skin Radiotherapy is an essential resource for practicing medical professionals such as radiation oncologists, dermatologists, radiation therapists and residents preparing for board examinations.
Radiotherapy Treatment Planning: Linear-Quadratic Radiobiology
by J. Donald Chapman Alan E. NahumUnderstand Quantitative Radiobiology from a Radiation Biophysics PerspectiveIn the field of radiobiology, the linear-quadratic (LQ) equation has become the standard for defining radiation-induced cell killing. Radiotherapy Treatment Planning: Linear-Quadratic Radiobiology describes tumor cell inactivation from a radiation physics perspective and of
Radiotracers in Drug Development
by Graham Lappin Simon TempleAlthough there are numerous books on drug metabolism, Radiotracers in Drug Development is unique in explaining how radiotracers are used to elucidate a drug's absorption, distribution, metabolism, and excretion (ADME). Covering traditional and recent technologies and applications, the book takes a strong industrial approach, discussing the b
Radium and the Secret of Life
by Luis A. CamposBefore the hydrogen bomb indelibly associated radioactivity with death, many chemists, physicians, botanists, and geneticists believed that radium might hold the secret to life. Physicists and chemists early on described the wondrous new element in lifelike terms such as “decay” and “half-life,” and made frequent references to the “natural selection” and “evolution” of the elements. Meanwhile, biologists of the period used radium in experiments aimed at elucidating some of the most basic phenomena of life, including metabolism and mutation. From the creation of half-living microbes in the test tube to charting the earliest histories of genetic engineering, Radium and the Secret of Life highlights previously unknown interconnections between the history of the early radioactive sciences and the sciences of heredity. Equating the transmutation of radium with the biological transmutation of living species, biologists saw in metabolism and mutation properties that reminded them of the new element. These initially provocative metaphoric links between radium and life proved remarkably productive and ultimately led to key biological insights into the origin of life, the nature of heredity, and the structure of the gene. Radium and the Secret of Life recovers a forgotten history of the connections between radioactivity and the life sciences that existed long before the dawn of molecular biology.
The Radium Girls: The Scary but True Story of the Poison that Made People Glow in the Dark
by Kate MooreExplore the unbelievable true story of America's glowing girls and their fight for justice in the young readers edition of the New York Times and USA Today bestseller The Radium Girls. This enthralling new edition includes all-new material, including a glossary, timeline, and dozens of bonus photos.Amid the excitement of the early twentieth century, hundreds of young women spend their days hard at work painting watch dials with glow-in-the-dark radium paint. The painters consider themselves lucky—until they start suffering from a mysterious illness. As the corporations try to cover up a shocking secret, these shining girls suddenly find themselves at the center of a deadly scandal.The Radium Girls: Young Readers Edition tells the unbelievable true story of these incredible women, whose determination to fight back saved countless lives.This new edition of the national bestseller is perfect for:Educators looking for history books for kids ages 9 to 12, nonfiction books for kids, biographies for kids, and real stories around the industrial revolution, chemistry, and scienceParents, educators, and librarians looking for stories about strong women, inspiring books for girls, childrens books about women in history, and famous women books for girlsYoung readers who want to read one of the most inspiring and shocking narratives of the early 20th century
Radon in Ground Water
by National Water Well Assoc.This new book focuses on sampling and analysis, radon and radium in water supply wells, predictive models, geologic and hydrogeologic controls that influence radon occurrence, monitoring radon and other radioactivity from geologic sources and mining impacts on occurrence of radioactivity in ground water. Also discussed are occurrence, testing, treatment, and reduction of radon from groundwater. Because the most severe health hazard from indoor radioactivity results from inhalation of short-lived radioactive decay products of radon, the EPA scheduled a major conference early in 1987 on Radon, Radium, and Other Radioactivity in Ground Water-Hydrogeologic Impact and Application to Indoor Airborne Contamination. The result is this book.
The Radon Transform and Local Tomography
by Alexander G. Ramm Alex I. KatsevichOver the past decade, the field of image processing has made tremendous advances. One type of image processing that is currently of particular interest is "tomographic imaging," a technique for computing the density function of a body, or discontinuity surfaces of this function. Today, tomography is widely used, and has applications in such fields as medicine, engineering, physics, geophysics, and security. The Radon Transform and Local Tomography clearly explains the theoretical, computational, and practical aspects of applied tomography. It includes sufficient background information to make it essentially self-contained for most readers.