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Rohrleitungen 2: Einsatz, Verlegung, Berechnung, Rehabilitation
by Hans-Burkhard Horlacher Ulf HelbigAls Springer Reference bietet die nunmehr 3. Auflage des Fachbuchs Rohrleitungen 1 und 2 eine anspruchsvolle, wissenschaftlich fundierte Fakten- und Wissenssammlung, die sich auf den kompletten Bereich der Rohrleitungstechnologie erstreckt. Das Buch stellt eine unentbehrliche Hilfe zum konstruktiven Verständnis, zur Funktionsweise und zum Betrieb von Rohrleitungen aller Art dar. Band 2 versteht sich als Erweiterung zum Band Rohrleitung 1 und dessen Schwerpunkten zu den unterschiedlichen Rohrwerkstoffen, der Rohrherstellung oder den betriebswichtigen Rohrleitungskomponenten. Der Teil Rohrleitung 2 richtet den Fokus auf die verschiedenen praktischen Einsatzfelder von Rohrleitungen, deren Bemessung und Berechnung, die Verlegung und den Einbau sowie die Rehabilitation bzw. Sanierung von Altleitungen. Zahlreiche Abbildungen und Diagramme, Tabellen sowie Beispiele runden die Ausführungen ab.
Rohrleitungs- und Apparatebau
by Günter ScholzVon einem erfahrenen Praktiker geschrieben, liefert der Band sowohl das theoretische als auch das praktische Wissen für die Planung und Ausführung von Rohrleitungen und Versorgungsrohrnetzen für Hochdruckdampf, Heißwasser, Druckluft und Kühlwasser. Der Autor leitet die strömungstechnischen und konstruktiven Grundlagen sowie alle für den Rohrleitungs- und den Apparatebau erforderlichen Berechnungsverfahren her und demonstriert ihre Anwendung in vollständig durchgerechneten Beispielen. Das Buch enthält Tabellen mit Stoffwerten sowie Arbeitsdiagramme.
ROI in Public Health Policy
by Subhash Pokhrel Lesley Owen Kathryn Coyle Doug CoyleThe demand for return in investment (ROI) analyses in public health is on the rise as a ‘business case’ needs to be presented before a public health programme can be funded. This book explains the science behind ROI analyses and shows how policy makers can learn the art of understanding and using it in the context of public health. Using examples drawn from the NICE ROI Tools, business cases for various alternative policy options around smoking cessation, improving physical activity and reducing alcohol use are presented. In addition, several examples of real-world decision problems facing public health investors are discussed to address the usefulness of ROI evidence in public health policy making.
The Rojas File
by Luc Wyn Pierre MonteagudoBook description: Mystery and secrecy come to light after 5 decades in an exciting story which reveals the complot to hide the inventions and discoveries of Doctor Rojas, a key scientist behind the landing of mankind on the moon. In the middle of the “Cold War” and while he was working for NASA, Doctor Rojas met with a president, travelled to the former Soviet Union, took the fateful decision to agree to an interview in Washington D.C. and afterward, what happened? The parties involved claim not to have any knowledge of him, but the truth is that this story is based on real events. While the 50th anniversary of the first manned landing on the moon approaches, we are presented with this fascinating book, which consists of two parts For starters it’s a tribute to the posthumous memory of astrophysicist Héctor. R. Rojas, who was able to travel to the moon on secret NASA flights, and in the second part, the author presents his lifelong thoughts about the UFO phenomenon. Without a doubt it’s an exciting story, written in simple and direct language.
The Role of Antioxidants in Longevity and Age-Related Diseases
by Bee Ling Tan Mohd Esa NorhaizanThe average life expectancy has increased worldwide in the recent decades. This has presented new challenges as old age brings the onset of diseases such as cancer, neurodegenerative disorders, cardiovascular disease, type 2 diabetes, arthritis, osteoporosis, stroke, and Alzheimer’s disease. Studies and research have shown the potential preventive and therapeutic roles of antioxidants in aging and age-related diseases by inhibiting the formation or disrupting the propagation of free radicals and thus increasing healthy longevity, enhancing immune function, and decreasing oxidative stress. This has made an antioxidant rich diet of increasing importance in battling the detrimental effects of the aging process.“The Role of Antioxidants in Longevity and Age-Related Diseases” is the book that compiles research on antioxidants and their biological mechanisms that mediate age-related diseases. This book covers the major issues linked to antioxidants, aging, and age-related diseases, including changes in organ systems over the lifespan, age-related oxidative stress-induced redox imbalance, inflammaging, implications of inflammation in aging and age-related diseases, and the important role of antioxidant-rich foods in their prevention and treatment of various age-related diseases. For researchers seeking a comprehensive single source on antioxidants and their roles in aging and age-related diseases, this novel text provides an up-to-date overview.
Role of Autophagy and Reactive Oxygen Species in Cancer Treatment: Principles and Current Strategies (Cancer Drug Discovery and Development)
by Neeraj Mishra Ravinder Kumar KaundalAutophagy is a catabolic process that eliminates damaged and faulty cellular components via lysosomes. It responds to adverse circumstances like nutritional deficiency, hypoxia, and oxidative damage. Reactive oxygen species (ROS) cause oxidative stress, which is a multidimensional chemical that drives various pathophysiological diseases, including cancer. In addition, the autophagy process has a double role, first preventing tumour formation, but later fostering tumour progression. A growing body of research suggests that autophagy and ROS have a complex interplay in which they can either prevent cancer growth or enhance disease genesis. While a combination of autophagy inhibitor and cytotoxic medicines is now being used in cancer treatment, investigating the potential of autophagy inhibitors for overcoming resistance to different anticancer medications and how this relates to the control of cancer micro environmental stressors raises several questions. Autophagy's dual functions as a safeguarding and cytotoxic process have drawn attention to its significance in the development of cancer.
The Role of Bacteria in Urology
by Dirk Lange Ben ChewThe aim of this book is to educate clinicians and basic scientists in the multiple roles that bacteria have as causative as well as therapeutic agents in urologic disease. Within this scope, clinicians will be introduced and educated about the basic mechanisms of bacterial pathogenesis that lead to disease, as well as the non-pathogenic mechanisms that contribute to the prevention and treatment of patients. Conversely, basic scientists will be educated about the clinical implications of bacterial based therapeutics and infections. By combining the basic science and clinical views, this book will serve to bring both basic scientists and clinicians onto an even plain that may raise ideas for future collaborative research.
The Role of Bioactive Lipids in Cancer, Inflammation and Related Diseases (Advances in Experimental Medicine and Biology #1161)
by Kenneth V. Honn Darryl C. ZeldinThe Organizing Committee of the 15th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases compiled a group of junior investigators to provide reviews on the topics they presented at the Puerto Vallarta Bioactive Lipids conference, as part of the book series, Advances in Experimental Medicine and Biology (AEMB). The book in this series will be titled Bioactive Lipids in Cancer, Inflammation and Related Diseases. Topics range from all classes of lipids including prostaglandins, resolvins, spingolipids, P450-derived lipids, endocannabanoids and phospholipids. The focus includes physiology, cell biology, and structural studies in organisms from bacteria to humans and how these studies addressed the role of lipids in various disease i.e. cancer, inflammation, diabetes, obesity, cardiovascular disease and others.
The Role of Biotechnology in a Sustainable Food Supply
by Molly Jahn Marty Matlock Jennie Popp Nathan Kemper"This publication addresses the role of biotechnology in a sustainable food supply in the 21st century. What sets this book apart is the thread that connects the broad subject matters and diverse author group. The chapters focus on the challenges, opportunities, success stories, barriers and risks associated with biotechnology. Authors are experts from around the world with broad backgrounds, experiences, and points of view. They include experts in the international aid and development, leaders in the developments and use of biotechnology in food applications, experts in food safety and risk associated with the use of biotechnology, and leaders in cosidering social, political and ethical issues surrounding the use of technology. The greatest strength of this book is the experitise and professional respect held by our authors and their diversity"--
The Role of Biotechnology in Improvement of Livestock
by Muhammad Abubakar Ali Saeed Oguz KulThis book examines how biotechnology can improve livestock breeding and farming, and thereby also animal products. In the first chapters the reader will discover which techniques and approaches are currently used to improve animal breeding, animal health and the value of animal products. Particular attention is given to reproduction techniques, animal nutrition and livestock vaccines that not only enhance animal health but also have a significant effect on human health by ensuring safe food procurement and preventing zoonotic diseases. In addition, modern biotechnology can increase not only productivity but also the consistency and quality of animal food, fiber and medical products. In the second part of the book, issues such as how animal biotechnology could affect the environment and the important topic of animal waste management are explored. In the concluding chapter, the authors discuss future challenges related to animal biotechnology. This work will appeal to a wide readership, from scientists and professionals working in animal production, to those in farm animal management and veterinary science.
Role of Capsaicin in Oxidative Stress and Cancer
by Sanjay K. SrivastavaThis book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival pathways including PI3K/Akt and the involvement of intrinsic mitochondrial cell death pathway.
The Role Of Centrosema, Desmodium, And Stylosanthes In Improving Tropical Pastures
by Peter P Rotar Robert L Burt J. L. Walker M. W. SilveyThis integrated collection describes the importance of forage legumes for pasture development and improvement in the tropics and subtropics. Leading agronomists review the magnitude of the need for pasture improvement; tropical and subtropical soil and climate environments; reports of the successful use of legumes in pasture development in a wet and a dry tropical environment; and the scope of the problem in terms of area to be developed and development logistics required. Three legume genera, Centrosema, Desmodium, and Stylosanthes, are discussed in detail--information is presented on taxonomy, adaptation, distribution, productivity, and usefulness--and considerable emphasis is placed on Rhizobium germplasm resources for these genera. A concluding section of technical essays addresses special considerations in using tropical legumes in pasture development and presents a coordinated multidisciplinary approach to legume exploration and evaluation.
Role of Circular Economy in Resource Sustainability (Sustainable Production, Life Cycle Engineering and Management)
by Ming Xu Pezhman Ghadimi Michael D. GilchristThis book aims to provide academic and industrial applications advancing the critical role of circular economy principles in the sustainability of various resources. The latest research and practice in resource sustainability are shared, discussed, and promoted. The core competency of this book revolves around providing recent advances in sustainable consumption and production implementations, developed tools for environmental and sustainability assessment, technological advancements in resource and waste management/treatment, and advances in waste reduction, reuse, recycling, and recovery. Resources are defined broadly to include (1) physical resources: metals, non-metallic minerals, energy, and water (2) biological resources: food, forestry, land, ecological systems, etc., and (3) “misplaced” resources: air emissions, water pollutants, and solid waste. Finally, legislation, and policy implications and recommendations for resources sustainability are concluded.
The Role of Clinical Studies for Pets with Naturally Occurring Tumors in Translational Cancer Research: Workshop Summary
by Sharyl J. NassTraditional preclinical mouse models of cancer have been very useful for studying the biology of cancer, however they often lack key characteristics of human cancers. As a result, many novel drug candidates fail in human clinical trials despite evidence of drug efficacy in those preclinical models. Thus, researchers are seeking new approaches to augment preclinical knowledge before undertaking clinical trials for human patients. Recently, there has been renewed interest in comparative oncology - the study of naturally developing cancers in animals as models for human disease - as one way to improve cancer drug development and reduce attrition of investigational agents. Tumors that spontaneously develop in pet dogs and other companion animals as a result of normal aging share many characteristics with human cancers, such as histological appearance, tumor genetics, biological behavior, molecular targets, and therapeutic response. In June 2015 the Institute of Medicine hosted a workshop to examine the rationale and potential for integrating clinical trials for pet patients with naturally occurring cancers into translational cancer research and development. Participants discussed the research needs, strategies, and resources to support greater integration of clinical trials for pets with cancer into translational research pathways, and challenges and potential solutions for facilitating that integration. This report summarizes the presentations and discussions from the workshop.
The Role of Corporate Sustainability in Asian Development: A Case Study Handbook in the Automotive and ICT Industries (Advances in Business Ethics Research #7)
by Gilbert Lenssen, Jay Hyuk Rhee and Fabien MartinezThis book examines the challenges faced by seven multinational companies - Intel, Lenovo, Samsung Electronics, ZTE, BMW Hyundai Motor Company, Mahindra and Mahindra - in their endeavour to contribute to the economic, environmental and social development of Asia. The lessons learned from the examination of these business practices may directly contribute to an increase in the practice of sustainable management and may as such contribute to positive economic, environmental and social impact of companies in this region. The cases are highly relevant for management theoreticians seeking to deepen our understanding of corporate sustainability in an area where scholars, practitioners and policy-makers can expect new questions, problems and challenges in the years ahead. The book is also of high interest to policy review agencies, policy makers and welfare economists seeking to support the development of a comprehensive sustainability framework for managing social and environmental issues in the context of Asia.
The Role of Design, Construction, and Real Estate in Advancing the Sustainable Development Goals (Sustainable Development Goals Series)
by Thomas Walker Carmela Cucuzzella Sherif Goubran Rana GeithThis edited book brings together insights from scholars and practitioners from many different fields to uncover the role of the construction and real estate sectors and how they align with the Sustainable Development Goals (SDGs). It follows a lifecycle-based approach to the topic, addressing the design, construction, management, investment, and regulatory dimensions of projects in the area. It expands the reader’s understanding of the built environment beyond the design and construction phases, which enables the collection to explore the links and transitions between different project phases and uncover new methodologies that aim to tackle systemic sustainable development challenges. The chapters’ comprehensive coverage allows the collection to capitalize on the strengths and weaknesses of the building industry, highlight emerging trends, and uncover some critical gaps that need to be addressed to attain the 2030 vision. This puts into perspective the interconnected nature of the SDGs and highlights the importance of multi-stakeholder collaborations in achieving them.
The Role of Exergy in Energy and the Environment (Green Energy and Technology)
by Sandro Nižetić Agis PapadopoulosThis book is devoted to the analysis and applications of energy, exergy, and environmental issues in all sectors of the economy, including industrial processes, transportation, buildings, and services. Energy sources and technologies considered are hydrocarbons, wind and solar energy, fuel cells, as well as thermal and electrical storage. This book provides theoretical insights, along with state-of-the-art case studies and examples and will appeal to the academic community, but also to energy and environmental professionals and decision makers.
Role of Exosomes in Biological Communication Systems
by Faisal A. Alzahrani Islam M. SaadeldinThis book reviews the role of exosomes and extracellular vesicles in both normal and pathological conditions. It first explains isolation methods for exosomes, and analyzes their fine structure and biological functions. Further, it highlights exosomes’ role as the key regulator in embryonic-maternal communication, and in the pathogenesis of various diseases, including cancer and urogenital, infectious, and neurodegenerative diseases. Moreover, it reviews the latest advances in using stem-cell-derived exosomes as a cell-free strategy in regenerative medicine, as well as the potential of exosomal microRNA as a promising non-invasive biomarker and targetable factor in cancer diagnosis and treatment. Lastly, it explores the use of natural and synthetic exosomes as nano-vehicles for efficient drug delivery.
The Role of Experimentation in Building Future Naval Forces
by Committee for the Role of Experimentation in Building Future Naval ForcesThe Department of Defense is in the process of transforming the nation’s armed forces to meet the military challenges of the 21st century. Currently, the opportunity exists to carry out experiments at individual and joint service levels to facilitate this transformation. Experimentation, which involves a spectrum of activities including analyses, war games, modeling and simulation, small focused experiments, and large field events among other things, provides the means to enhance naval and joint force development. To assist the Navy in this effort, the Chief of Naval Operations (CNO) asked the National Research Council (NRC) to conduct a study to examine the role of experimentation in building future naval forces to operate in the joint environment. The NRC formed the Committee for the Role of Experimentation in Building Future Naval Forces to perform the study.
Role of Folliculo-luteal Function in Human Reproduction
by György SiklósiThis book is the first to explain fully the crucial role of folliculo-luteal function in recurrent miscarriage, unexplained infertility, preterm birth, intrauterine growth retardation, preeclampsia, random chromosomal abnormalities, and age-related reproductive disorders. In addition it describes treatments to avoid these conditions and proposes a novel method, "hormonal wedge resection", that can successfully cure infertility associated with polycystic ovary syndrome. Importantly, the conclusions drawn in this book are based on the therapeutic results observed in a representative patient population. The method developed by the author to quantitatively diagnose the hormonal insufficiency of ovulatory cycles (folliculo-luteal insufficiency, FLI) has made it possible to recognize the formerly unclear importance of this function in human reproduction. Folliculo-luteal function determines the conditions of placentation and thus the features of the developed placenta and the outcome of pregnancy. Different grades of FLI are associated with consequences of varying severity that can be prevented by normalization of folliculo-luteal function prior to conception. This book will be required reading for all obstetricians and gynecologists.
The Role of Fuels in Transforming Energy End-Use in Buildings and Industrial Processes (Synthesis Lectures on Engineering, Science, and Technology)
by Praveen Cheekatamarla Kyle Gluesenkamp Stephen Kowalski Zhenning Li Saad JajjaEnergy-efficient technologies are necessary to lower the carbon footprint for a transition towards clean energy in a sustainable manner. This book examines what role fuels have in the transformation of end-use in buildings and industrial processes. Energy-efficient technologies are necessary to lower the carbon footprint for a transition towards clean energy in a sustainable manner. Efficient utilization of primary energy resources, including renewables, to support the current and future energy needs while targeting grid resiliency, energy, and environmental security at an affordable cost is of significant value. The author analyzes heat pumps, fuel-driven thermal providers, and power systems configurations and looks at the sensitivity of the electrical grid's carbon intensity and tariff towards carbon footprint and energy costs compared with fuel-driven technologies. The role of low-carbon, zero-carbon, and carbon-negative fuels, such as power-to-gas (P2G), power-to-liquid (PtL), hydrogen, and biogas, in conjunction with polygeneration technologies, are discussed. This book also examines two different scenarios focused on the sensitivity of the pace of decarbonization of the electrical grid and fuel supply on operational energy-related carbon emissions.Compares electricity versus fuel as a primary energy sourceExplores the role of fuels in the decarbonization journey Examines the value proposition of currently available energy solutions
Role of Giant Honeybees in Natural and Agricultural Systems
by Dharam P. AbrolRole of Giant Honeybees in Natural and Agricultural Systems provides multidisciplinary perspective about the different facets of giant honeybees. Giant honeybees–Apis dorsata and Apis laboriosa are excellent pollinators of crops, fruits, and vegetables in cultivated and natural lanscapes. Their large size, long foraging range, and large work force make them the most spectacular of all honeybee species for crop pollination and honey production. Due to their decline, ecosystems and global food security are being threatened. This book is the first of its kind which deals in detail on varied aspects of giant honeybee biology, management, conservation strategies for protecting biodiversity and enhancing crop productivity. It aims to promote a large, diverse, sustainable, and dependable bee pollinator workforce that can meet the challenge for optimizing food production in 21st century. SALIENT FEATURES: Covers the latest information on various aspects of biology of giant honeybees and brings the latest advances together in a single volume for researchers and advanced level students Provides an excellent source of advanced study material for academics, researchers and students and programme planners Provides an excellent source of livelihood in mountainous areas and marginal farmers Deals with biology, management and conservation strategies for protecting biodiversity and enhancing crop productivity. Excellent pollinator of tropical and subtropical crops, fruits, vegetables, etc. less prone to diseases and enemies This book will be useful for pollination biologists, honeybee biologists, scientists working in agriculture, animal behavior, conservation, biology, ecology, entomologists, environmental biologists, etc.
The Role of GIS in COVID-19 Management and Control
by Esra OzdenerolGeographic Information System (GIS) is one of the most important tools to help us understand public health and many aspects of our lives. Because of COVID-19, GIS has been brought into the spotlight more than ever before. People and civic leaders worldwide are turning to maps and real-time surveillance data to make sense of what has been happening in the world and to get answers to important questions on every aspect of this pandemic. This book examines the role of GIS in managing and controlling the spread of COVID-19 through 12 global projects and a multidisciplinary approach. It explains the innovative uses of GIS not only limited to data organization and data access, but also how improved GIS tools are used to make decisions, plan, and communicate various measures of control in both local and full-scale outbreaks during the COVID-19 pandemic. Features: Provides cutting-edge GIS visualization, spatial temporal pattern, and hot spot tracking applications used for predictive modeling of COVID-19. Includes real-world case studies with broad geographic scope that reflect COVID-19 trends in cases, deaths, and vaccinations. Provides lifestyle segmentation analysis on the risk of transmission of COVID-19 and spatial patterns of vaccination hesitancy. Highlights real-world issues brought to light with the help of GIS, such as social discrimination, inequalities in women’s access to mental health care, and analyzes the risk of transmission due to vaccination hesitancy. Shows the use of GIS and spatial analysis in pandemic mapping, management, and control from masking and social distancing to testing site locations accounting for at-risk and vulnerable populations. Discusses facilitating policy making with GIS. Edited by a very talented medical geographer and GIS Professor Dr. Esra Ozdenerol, this book highlights key GIS capabilities and lessons learned during the COVID-19 response that can help communities prepare for the next crisis. It is a great resource for industry professionals and experts in health care, public health and safety, disaster management, and for students, academics, and researchers interested in applying GIS and spatial analysis to the study of COVID-19 and other pandemics.
The Role of Glycosylation in Health and Disease (Advances in Experimental Medicine and Biology #1325)
by Gordan Lauc Irena Trbojević-AkmačićGlycobiology is an emerging field of studying glycans (sugars) and glycoconjugates that are essentially involved in almost all biological processes, from fine-tuning glycoprotein function to protein-protein interactions, signaling, immune response, host-pathogen interactions, etc. However, due to structural complexity of glycans and analytical challenges this exciting field was lagging behind other areas of biology. With technological advancements growing number of glycans’ functions are being discovered and the study of glycans is becoming a cutting-edge discipline in basic and clinical research.Despite recent developments in glycobiology field, many aspects of glycosylation process still remain unknown, both in a healthy human organism and in pathological states. Human glycome is dynamic and changes with physiological triggers, immune challenges and disease. Atypical glycosylation is consequently a subject of disease biomarker research, and a target for therapeutic interventions. On the other hand, properties of glycosylated biotherapeutics are predominantly determined by their glycans.The Role of Glycosylation in Health and Disease provides a comprehensive overview of types and functions of glycans in a healthy human organism as well as their role in pathophysiology of different diseases and efficiency of glycosylated biotherapeutics. Written by the experts in the field, this book aims to bring glycobiology field closer to students, researchers in life sciences and professionals in biopharmaceutical industry.
The Role of Green Chemistry in Biomass Processing and Conversion
by Haibo Xie Nicholas GathergoodSets the stage for the development of sustainable, environmentally friendly fuels, chemicals, and materials Taking millions of years to form, fossil fuels are nonrenewable resources; it is estimated that they will be depleted by the end of this century. Moreover, the production and use of fossil fuels have resulted in considerable environmental harm. The generation of environmentally friendly energy from renewable sources such as biomass is therefore essential. This book focuses on the integration of green chemistry concepts into biomass processes and conversion in order to take full advantage of the potential of biomass to replace nonsustainable resources and meet global needs for fuel as well as other chemicals and materials. The Role of Green Chemistry in Biomass Processing and Conversion features contributions from leading experts from Asia, Europe, and North America. Focusing on lignocellulosic biomass, the most abundant biomass resource, the book begins with a general introduction to biomass and biorefineries and then provides an update on the latest advances in green chemistry that support biomass processing and conversion. Next, the authors describe current and emerging biomass processing and conversion techniques that use green chemistry technologies, including: Green solvents such as ionic liquids, supercritical CO2, and water Sustainable energy sources such as microwave irradiation and sonification Green catalytic technologies Advanced membrane separation technologies The last chapter of the book explores the ecotoxicological and environmental effects of converting and using fuels, chemicals, and materials from biomass. Recommended for professionals and students in chemical engineering, green chemistry, and energy and fuels, The Role of Green Chemistry in Biomass Processing and Conversion sets a strong foundation for the development of a competitive and sustainable bioeconomy. This monograph includes a Foreword by James Clark (University of York, UK).