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Scaffolding In Tissue Engineering
by Peter X. Ma Jennifer ElisseeffThe growing interest in scaffolding design and increasing research programs dedicated to regenerative medicine corroborate the need for Scaffolding in Tissue Engineering. While certain books and journal articles address various aspects in the field, this is the first current, comprehensive text focusing on scaffolding for tissue engineering.
Scalable Innovation: A Guide for Inventors, Entrepreneurs, and IP Professionals
by Eugene Shteyn Max ShteinInnovation is a primary source of economic growth, and yet only one idea out of 3,000 becomes a successful product or service. Scalable Innovation: A Guide for Inventors, Entrepreneurs, and IP Professionals introduces a model for the innovation process, helping innovators to understand the nature and timing of opportunities and risks on the path to
Scalable Pattern Recognition Algorithms
by Pradipta Maji Sushmita PaulThis book addresses the need for a unified framework describing how soft computing and machine learning techniques can be judiciously formulated and used in building efficient pattern recognition models. The text reviews both established and cutting-edge research, providing a careful balance of theory, algorithms, and applications, with a particular emphasis given to applications in computational biology and bioinformatics. Features: integrates different soft computing and machine learning methodologies with pattern recognition tasks; discusses in detail the integration of different techniques for handling uncertainties in decision-making and efficiently mining large biological datasets; presents a particular emphasis on real-life applications, such as microarray expression datasets and magnetic resonance images; includes numerous examples and experimental results to support the theoretical concepts described; concludes each chapter with directions for future research and a comprehensive bibliography.
Scalar Boson Decays to Tau Leptons: in the Standard Model and Beyond (Springer Theses)
by Cécile CaillolThis thesis presents a study of the scalar sector in the standard model (SM), as well as various searches for an extended scalar sector in theories beyond the SM (BSM). The first part of the thesis details the search for an SM Higgs boson decaying to taus, and produced by gluon fusion, vector boson fusion, or associated production with a vector boson, leading to evidence for decays of the Higgs boson to taus. In turn, the second part highlights several searches for an extended scalar sector, with scalar boson decays to taus. In all of the analyses presented, at least one scalar boson decays to a pair of taus. The results draw on data collected by the Compact Muon Solenoid (CMS) detector during proton–proton collisions with a center-of-mass energy of 7 or 8 TeV.
Scalar Fields in Numerical General Relativity: Inhomogeneous Inflation and Asymmetric Bubble Collapse (Springer Theses)
by Katy CloughThis book explores the use of numerical relativity (NR) methods to solve cosmological problems, and describes one of the first uses of NR to study inflationary physics. NR consists in the solution of Einstein’s Equation of general relativity, which governs the evolution of matter and energy on cosmological scales, and in systems where there are strong gravitational effects, such as around black holes. To date, NR has mainly been used for simulating binary black hole and neutron star mergers like those detected recently by LIGO. Its use as a tool in fundamental problems of gravity and cosmology is novel, but rapidly gaining interest. In this thesis, the author investigates the initial condition problem in early universe cosmology – whether an inflationary expansion period could have “got going” from initially inhomogeneous conditions – and identifies criteria for predicting the robustness of particular models. State-of-the-art numerical relativity tools are developed in order to address this question, which are now publicly available.
Scalar Mismatches in Metropolitan Water Governance: A Comparative Study of São Paulo and Mexico City (Water Governance - Concepts, Methods, and Practice)
by Francine van den BrandelerThe book provides insights into the particular nature of water-related challenges in metropolitan regions of the Global South and the “scalar mismatches” that prevent their sustainable and inclusive development. It argues for the adoption of a metropolitan water governance approach to assess these challenges, including the drivers and institutions that shape these, and the policy instruments at river basin and urban scales that aim to address these. The cases of Mexico City and São Paulo, as two mega-cities with a wide ranging of water-related challenges, present lessons to other fast growing urban agglomerations on the variety of possible responses as well as obstacles to their effectiveness that receive little attention.
Scale Formation in Heat Exchangers
by Mohammad Varnaseri Seyed Mohsen PeyghambarzadehThis book brings together a wide range of current research to create a holistic understanding of fouling. It draws upon practical and laboratory experiences spanning many years. While offering an overview of various fouling types, the book's emphasis is on crystallization fouling, a facet seldom addressed in the existing literature. Furthermore, this book goes beyond theory by providing practical examples for heat exchanger design, incorporating the pivotal consideration of fouling's impact. It focuses especially on calcium salts such as calcium carbonate and calcium sulfate.Fouling formation represents a ubiquitous challenge across diverse industrial sectors, spanning oil, gas, petrochemicals, food, pharmaceuticals, and power generation. This encroaching fouling, prevalent within heating equipment, not only jeopardizes the integrity of machinery but also significantly saps energy resources. Consequently, extensive research efforts have been undertaken to comprehensively explore fouling formation through both experimental and theoretical avenues across various heating apparatuses. The book's mission is to facilitate a broader comprehension of crystallization fouling research, revealing the various factors influencing this form of fouling. Additionally, it critiques prior research endeavors, identifying their strengths and weaknesses while pinpointing potential avenues for future investigation
Scale Invariance
by Dick HenriksenBringing the concepts of dimensional analysis, self-similarity, and fractal dimensions together in a logical and self-contained manner, this book reveals the close links between modern theoretical physics and applied mathematics. The author focuses on the classic applications of self-similar solutions within astrophysical systems, with some general theory of self-similar solutions, so as to provide a framework for researchers to apply the principles across all scientific disciplines. He discusses recent advances in theoretical techniques of scaling while presenting a uniform technique that encompasses these developments, as well as applications to almost any branch of quantitative science. The result is an invaluable reference for active scientists, featuring examples of dimensions and scaling in condensed matter physics, astrophysics, fluid mechanics, and general relativity, as well as in mathematics and engineering.
Scale Theory: A Nondisciplinary Inquiry
by Joshua DiCaglioA pioneering call for a new understanding of scale across the humanities How is it possible that you are—simultaneously—cells, atoms, a body, quarks, a component in an ecological network, a moment in the thermodynamic dispersal of the sun, and an element in the gravitational whirl of galaxies? In this way, we routinely transform reality into things already outside of direct human experience, things we hardly comprehend even as we speak of DNA, climate effects, toxic molecules, and viruses. How do we find ourselves with these disorienting layers of scale? Enter Scale Theory, which provides a foundational theory of scale that explains how scale works, the parameters of scalar thinking, and how scale refigures reality—that teaches us how to think in terms of scale, no matter where our interests may lie. Joshua DiCaglio takes us on a fascinating journey through six thought experiments that provide clarifying yet provocative definitions for scale and new ways of thinking about classic concepts ranging from unity to identity. Because our worldviews and philosophies are largely built on nonscalar experience, he then takes us slowly through the ways scale challenges and reconfigures objects, subjects, and relations. Scale Theory is, in a sense, nondisciplinary—weaving together a dizzying array of sciences (from nanoscience to ecology) with discussions from the humanities (from philosophy to rhetoric). In the process, a curious pattern emerges: attempts to face the significance of scale inevitably enter terrain closer to mysticism than science. Rather than dismiss this connection, DiCaglio examines the reasons for it, redefining mysticism in terms of scale and integrating contemplative philosophies into the discussion. The result is a powerful account of the implications and challenges of scale, attuned to the way scale transforms both reality and ourselves.
Scale-Sensitive Governance of the Environment
by Paul Opdam Nico Polman Frans Padt Catrien TermeerSensitivity to scales is one of the key challenges in environmental governance. Climate change, food production, energy supply, and natural resource management are examples of environmental challenges that stretch across scales and require action at multiple levels. Governance systems are typically ill-equipped for this task due to organisational and jurisdictional specialisation and short-term planning horizons. Further to this, scientific knowledge is fragmented along disciplinary lines and research traditions in academia and research institutions. State-of-the-art, Scale-Sensitive Governance of the Environment addresses these challenges by establishing the foundation for a new, trans-disciplinary research field. It brings together and reframes a variety of disciplinary approaches, using the idea of scales to create a conceptual and methodological basis for scale-sensitive governance of the environment from both a natural and social science perspective. This volume presents new visions, methods and innovative applications of thinking and decision making across scales in space and time to develop a holistic view on the subject. It is unique in providing: F analysis on how spatial, temporal, and governance scales are constructed, politically and scientifically defined, institutionalized in governance practices, and strategically used in policy discourses F details on how current environmental governance practices can be enriched by the use of theory on scale, with specific research themes to show the benefits of recognizing scales in empirical research F insightful case studies drawn from countries in the Americas, Eastern and Southern Africa, Europe, and South and Southeastern Asia, covering a wide range of environmental topics including biodiversity, climate change, commodities (tea and palm oil), cultural landscapes, energy, forestry, natural resource management, pesticides, urban development, and water management. With its comprehensive coverage of scale and scaling issues and convergence of widely different scientific approaches, this book is essential for environmental scientists, policy makers and planners, also conservation biologists and ecologists who are involved in modeling climate change impacts and sustainability. This reference will also benefit students of environmental studies, and all those who seek a response to the urgent environmental governance challenges for the decades ahead.
Scale-Up and Optimization in Preparative Chromatography: Principles and Biopharmaceutical Applications (Chromatographic Science Ser. #Vol. 88)
by Anurag S. RathorePresenting guidelines to predict and improve separation system performance, this book contains numerous case studies illustrating the practice of scale-up principles in process development. It offers solutions to limitations that occur in real-world purification schemes; methods to model, optimize, and characterize nonlinear separation processes; data comparisons from all stages of production; and industrial separation schemes for products such as synthetic molecules, antibody fragments, IgG, growth factors, and plasmid DNA. The book covers external constraints, separation economics, correlations for transport and kinetic phenomena, and the configuration and parameters of column design.
Scale-up: Modellübertragung in der Verfahrenstechnik
by Marko ZlokarnikDie Übertagung von Verfahren aus dem Labor-bzw. dem Techni-kumsmaßstab in den industriellen maßstab einer Produktiosanlage ist eine der wichtigsten ingenieurstechnischen Aufgaben in der chemischen Industrie. Die einzige zuverlässige Methode dazu basiert auf der Darstellung von Versuchsergebnissen im zutreffenden dimensions-analytischen Raum, der sich als maßstabsinvariant erweist. Das Buch ist in zwei Teile gegliedert: In der ersten Hälfte werden die vertiefte mathematische Vorkenntnisse dieses Themengebiet näherzubringen. Diskutiert werden die Grundlagen der Dimensionsanalyse, die Behandlung von temperaturabhängigen und von rheologischen Stoffwerten und die Modellübertragung bei Nichtverfügbarkeit von Modellstoffsystemen, sowie bei partieller Ähnlichkeit/ All dies wird dem leser anhand von 20 modernen Beispielen aus der heutigen verfahrenstechnischcen Praxis illustriert, der sich mit 25 in dieser Auflage neu hinzugekommenen Übungsaufgaben sein Verständnis aktive erarbeiten und anhand der Lösungen kontrollieren kann. Im zweitem Teil des Buches werden die einzelnen verfahrenstechnischen Grundoperationen aus den Bereichen mechanische, thermische und chemische Verfahrenstechnik aus der Sicht der Dimensionsanalyse und der Modellübertragung beispielhaft behandelt, und es werden für jede Operation die Maßstabsübertragungsregeln vorgestellt und diskutiert. Das vorliegende Buch wendet sich dementsprechend an Studenten wie auch bereits auf dem gebiet tätige Ingenieure, Chemiker und Verfahrenstechniker.
Scale: The Universal Laws of Growth, Innovation, Sustainability, and the Pace of Life in Organisms, Cities, Economies, and Companies (Santa Fe Institute Studies On The Sciences Of Complexity)
by Geoffrey WestFrom one of the most influential scientists of our time, a dazzling exploration of the hidden laws that govern the life cycle of everything from plants and animals to the cities we live in.Visionary physicist Geoffrey West is a pioneer in the field of complexity science, the science of emergent systems and networks. The term “complexity” can be misleading, however, because what makes West’s discoveries so beautiful is that he has found an underlying simplicity that unites the seemingly complex and diverse phenomena of living systems, including our bodies, our cities and our businesses. Fascinated by aging and mortality, West applied the rigor of a physicist to the biological question of why we live as long as we do and no longer. The result was astonishing, and changed science: West found that despite the riotous diversity in mammals, they are all, to a large degree, scaled versions of each other. If you know the size of a mammal, you can use scaling laws to learn everything from how much food it eats per day, what its heart-rate is, how long it will take to mature, its lifespan, and so on. Furthermore, the efficiency of the mammal’s circulatory systems scales up precisely based on weight: if you compare a mouse, a human and an elephant on a logarithmic graph, you find with every doubling of average weight, a species gets 25% more efficient—and lives 25% longer. Fundamentally, he has proven, the issue has to do with the fractal geometry of the networks that supply energy and remove waste from the organism’s body. West’s work has been game-changing for biologists, but then he made the even bolder move of exploring his work’s applicability. Cities, too, are constellations of networks and laws of scalability relate with eerie precision to them. Recently, West has applied his revolutionary work to the business world. This investigation has led to powerful insights into why some companies thrive while others fail. The implications of these discoveries are far-reaching, and are just beginning to be explored. Scale is a thrilling scientific adventure story about the elemental natural laws that bind us together in simple but profound ways. Through the brilliant mind of Geoffrey West, we can envision how cities, companies and biological life alike are dancing to the same simple, powerful tune.
Scale: The Universal Laws of Life and Death in Organisms, Cities and Companies
by Geoffrey WestGeoffrey West's research centres on a quest to find unifying principles and patterns connecting everything, from cells and ecosystems to cities, social networks and businesses.Why do organisms and ecosystems scale with size in a remarkably universal and systematic fashion?Is there a maximum size of cities? Of animals and plants? What about companies?Can scale show us how to create a more sustainable future?By applying the rigour of physics to questions of biology, visionary physicist Geoffrey West found that despite the riotous diversity in the sizes of mammals, they are all, to a large degree, scaled versions of each other. This speaks to everything from how long we can expect to live to how many hours of sleep we need. He then made the even bolder move of exploring his work's applicability to cities and to the business world. These investigations have led to powerful insights about the elemental natural laws that bind us together in profound ways, and how all complex systems are dancing to the same simple tune, however diverse and unrelated they may seem.
Scale: The Universal Laws of Life and Death in Organisms, Cities and Companies
by Geoffrey WestGeoffrey West's research centres on a quest to find unifying principles and patterns connecting everything, from cells and ecosystems to cities, social networks and businesses.'An absolutely riveting read . . . groundbreaking' Marcus du Sautoy'This book will expand your thinking from three dimensions to four' Nassim Nicholas Taleb'Scale is a firework display of popular science' Niall Ferguson'This is an important and original book, of immense scope' Lord Martin Rees, Astronomer RoyalScale addresses big, urgent questions about global sustainability, population explosion, urbanization, ageing, cancer, human lifespans and the increasing pace of life, but also encourages us to question the world around us. Why can we live for 120 years but not for a thousand? Why does the pace of life continually increase? Why do mice live for just two or three years and elephants for up to 75? Why do companies behave like mice, and are they all destined to die? Do cities, companies and human beings have natural, pre-determined lifespans? Are we just a fascinating experiment in natural selection that is ultimately doomed to fail? And what is the origin of the magic number 4 that seems to determine much of physiology and life-history from birth to death?Read by Bruce Mann(p) 2017 Penguin Random House
Scale: Understanding the Environment
by Cristian SuteanuThis book provides up-to-date, in-depth and accessible information on the concept of scale, and focuses on its applications in geography, Earth science, environmental science, and other fields in which the environment plays a significant role. Although the book presents methods and applications as a response to practical challenges, it is primarily concept-centered: it identifies a set of distinct, yet related notions of “scale”, analyzing and elucidating their evolving meanings in a systematic way. Concepts are defined with a focus on their practical operational applicability, and the introduction of methods is supported by concrete examples. The book links theoretical insights to illustrating applications, involving a broad range of themes, from maps, fractals, and chaos theory to fine art and literature. It approaches the subject in a spatial, temporal, and spatio-temporal context, including a wide diversity of spatial features from Earth and other planets, as well as time series and space-time patterns. This monograph is expected to be useful especially because in practice the various scale-focused concepts are not neatly separated and immiscible. It is therefore helpful for scholars in physical and human geography, Earth and environmental sciences, and other fields, to benefit from a clear conceptual framework that distinguishes and illuminates the various scale-related concepts and their interconnections. Selected chapters can also support a deeper understanding of the concept of scale for graduate and undergraduate students in geography, the natural sciences, and the humanities. Information on recommended additional literature and comments about specific sources offer a guide to further reading on the topics addressed in the book.
Scales (Learn About)
by Eric GeronLet's learn all about the different types of animal coverings!Which animals have scales? Fish! Did you know that some birds, reptiles, and mammals can also have scales? Discover all the incredible ways scales help animals survive. With amazing photos and lively text, this book explains how scales help animals stay warm or cool, move, protect themselves, and more! Get ready to learn all about scales!ABOUT THE SERIES:Animals have different body coverings for different reasons. Some animals use their coverings to keep warm or stay cool, others use them for protection, and can either stand out or blend in. Some animals even use their coverings to move! This vibrant new set of Learn About books gives readers a close-up look at five different animal coverings, from fur and feathers to skin, scales, and shells. Each book is packed with photographs and fun facts that explore how each covering suits the habitat, diet, survival, and life cycle of various animals in the natural world.
Scaling Impact: Finance and Investment for a Better World
by Kusisami HornbergerThe global challenges confronting us — climate change, poverty, inequality, and many others — can feel overwhelming. Those of us who believe in market-based solutions to these challenges get even more disheartened when we regularly see our existing capitalist system failing us, often causing more harm than good. Many examples show how the capitalist tools of finance and investment can and make real, positive impact. Approaches like blended finance and impact investing can help accelerate progress against the world’s biggest remaining collective challenges. Yet use of these improved capitalist approaches remains far too subscale. Blended finance and impact investing remain 15 to 200 times smaller than traditional approaches to finance and investment. How can we continue to make capitalism work better by scaling these approaches and others? This book looks at how we can start making these necessary changes using strategies, structures, and practices that take advantage of capitalism's strengths. Its goal is to demonstrate how a reimagined financial system can be more inclusive and accountable to all. By shifting away from extractive, short-term practices in the name of shareholder primacy, we can move toward a system that values the role of all stakeholders.
Scaling Laws in Dynamical Systems (Nonlinear Physical Science)
by Edson Denis LeonelThis book discusses many of the common scaling properties observed in some nonlinear dynamical systems mostly described by mappings. The unpredictability of the time evolution of two nearby initial conditions in the phase space together with the exponential divergence from each other as time goes by lead to the concept of chaos. Some of the observables in nonlinear systems exhibit characteristics of scaling invariance being then described via scaling laws. From the variation of control parameters, physical observables in the phase space may be characterized by using power laws that many times yield into universal behavior. The application of such a formalism has been well accepted in the scientific community of nonlinear dynamics. Therefore I had in mind when writing this book was to bring together few of the research results in nonlinear systems using scaling formalism that could treated either in under-graduation as well as in the post graduation in the several exact programs but no earlier requirements were needed from the students unless the basic physics and mathematics. At the same time, the book must be original enough to contribute to the existing literature but with no excessive superposition of the topics already dealt with in other text books. The majority of the Chapters present a list of exercises. Some of them are analytic and others are numeric with few presenting some degree of computational complexity.
Scaling Methods in Soil Physics
by Yakov Pachepsky David E. Radcliffe H. Magdi SelimThe scaling issue remains one of the largest problems in soil science and hydrology. This book is a unique compendium of ideas, conceptual approaches, techniques, and methodologies for scaling soil physical properties. Scaling Methods in Soil Physics covers many methods of scaling that will be useful in helping scientists across a range of soil-rel
Scaling Relations in Experimental Ecology
by Gardner Robert H. W. Michael Kemp John E. Petersen Victor S. KennedyThis book discusses the impact of recent advances in the theory of "scaling relationships" and identifies critical issues that must be considered if experimental results are used to understand the temporal and spatial scales of actual ecosystems.
Scaling in Ecology with a Model System (Monographs in Population Biology #118)
by Aaron M. Ellison Nicholas J. GotelliA groundbreaking approach to scale and scaling in ecological theory and practiceScale is one of the most important concepts in ecology, yet researchers often find it difficult to find ecological systems that lend themselves to its study. Scaling in Ecology with a Model System synthesizes nearly three decades of research on the ecology of Sarracenia purpurea—the northern pitcher plant—showing how this carnivorous plant and its associated food web of microbes and macrobes can inform the challenging question of scaling in ecology.Drawing on a wealth of findings from their pioneering lab and field experiments, Aaron Ellison and Nicholas Gotelli reveal how the Sarracenia microecosystem has emerged as a model system for experimental ecology. Ellison and Gotelli examine Sarracenia at a hierarchy of spatial scales—individual pitchers within plants, plants within bogs, and bogs within landscapes—and demonstrate how pitcher plants can serve as replicate miniature ecosystems that can be studied in wetlands throughout the United States and Canada. They show how research on the Sarracenia microecosystem proceeds much more rapidly than studies of larger, more slowly changing ecosystems such as forests, grasslands, lakes, or streams, which are more difficult to replicate and experimentally manipulate.Scaling in Ecology with a Model System offers new insights into ecophysiology and stoichiometry, demography, extinction risk and species distribution models, food webs and trophic dynamics, and tipping points and regime shifts.
Scaling up SDGs Implementation: Emerging Cases from State, Development and Private Sectors (Sustainable Development Goals Series)
by Godwell Nhamo Vuyo Mjimba Gbadebo O. A. OdularuThis volume challenges global leaders and citizenry to do more in order to resource the implementation of the 2030 Agenda for Sustainable Development (AfSD) and its 17 interwoven Sustainable Development Goals (SDGs). Starting from the concept ‘we cannot manage what we cannot measure’, the book presents some cases showing how to draw national level baselines for the domestication and localisation of the SDGs seeking to provide a clear roadmap towards achieving the 2030 AfSD. Scaling up SDGs Implementation is targeted at the United Nations, national and state governments, sub-national governments, the corporate sector and civil society, including higher education institutes, labour groups, non-governmental organisations and youth movements. The book is cognizant of these institutions’ common, but differentiated responsibilities and capabilities within their socio-political, environmental and economic conditions. The book presents case studies of how the corporate sector has been scaling up SDGs implementation, from the tourism sector, insurance, to the aviation and agricultural sectors. To make sure that no one is left behind, the volume includes cases on solutions for pressing environmental and socio-economic problems ranging from cooperatives in Brazil to the conservation of springs in Zimbabwe. The matter of finding synergies between the climate SDG and the Paris Agreement’s Nationally Determined Contributions (NDCs) is elaborated at length. Lastly, the book discusses how institutions of higher education remain critical pillars in SDGs scaling up, with cases of curriculum re-orientation in South Africa to the rolling out of the Women’s University in Africa. In this context, this volume challenges every global citizen and organization to invest every effort into making the implementation of the SDGs a success as we welcome the second four to five year segment down the road to the year 2030.
Scaling-up Solutions for Farmers: Technology, Partnerships and Convergence
by Tapas Bhattacharyya K. V. Raju Suhas P. WaniThis book provides a unique account of cross-sectoral innovations through efficient partnerships based on the hands-on experience of internationally renowned contributors specialised in the field of Science of Delivery. The challenges and lessons learned from large development initiatives based in Asia, and from the work undertaken by international research institutions, such as the FAO, are brought together in this book to benefit development agencies, policy makers, corporates, post graduate students, farmers’ organizations, and those involved in supplying agricultural inputs and/or buying agricultural produce, particularly in developing countries within Asia and Africa. Through a number of case studies the book describes how the consortium approach of capacity building for equitable and efficient benefits, collective action, and convergence, will benefit millions of small farm-holders in different regions of Asia
Scaling: Why is animal size so important?
by Knut Schmidt-NielsenThis book is about the importance of animal size. We tend to think of animal function in chemical terms and talk of water, salts, proteins, enzymes, oxygen, energy, and so on. We should not forget, however, that physical laws are equally important, for they determine rates of diffusion and heat transfer, transfer of force and momentum, the strength of structures, the dynamics of locomotion, and other aspects of the functioning of animal bodies. Physical laws provide possibilities and opportunities for an organism, yet they also impose constraints, setting limits to what is physically possible. This book aims to give an understanding of these rules because of their profound implications when we deal with animals of widely different size and scale. The reader will find that the book raises many questions. Remarkable and puzzling information makes it read a little like a detective story, but the last chapter, instead of giving the final solution, neither answers all questions nor provides one great unifying principle.