- Table View
- List View
Pseudocapacitors: Fundamentals to High Performance Energy Storage Devices (Engineering Materials)
by Ram K. GuptaThis book provides an overview of pseudocapacitive materials, including their fundamentals, synthetic methods, architectural enhancements to boost their properties, and emerging materials. It covers numerous strategies to enhance their performance, such as altering morphology, doping, introducing multivalent ions, designing devices, and utilizing emerging pseudocapacitive materials. The book also delves into fundamental approaches for fine-tuning the properties of pseudocapacitive materials and explores their applications in energy storage devices, with a specific focus on emerging pseudocapacitive materials and their utilization in energy storage devices.
Pseudogap and Precursor Superconductivity Study of Zn doped YBCO
by Ece UykurIn this thesis, the pseudogap and the precursor superconducting state, which are of great importance in clarifying the superconductivity mechanism in high-temperature cuprate superconductors, are investigated with a c-axis optical study in YBa2(Cu1-xZnx)3Oy. Testing was performed over a wide energy range with smaller temperature intervals for several Zn-substituted samples, as well as for several carrier-doping levels. A spectral weight (SW) analysis, in which the pseudogap behavior can be separated from the superconducting condensate with the SW transfer to the high-energy region, revealed that the pseudogap is not the precursor of the superconductivity (carriers moving to the high-energy region with pseudogap opening never contribute to the superconducting condensation). Moreover, the high-energy transfer continues even below Tc for the Zn-substituted samples (in which we weaken the superconductivity), which gives evidence to the coexistence of the pseudogap and the superconducting gap below Tc. On the other hand, the analysis of optical conductivity revealed that a precursor state to superconductivity can be defined at temperatures much higher than Tc. The superconducting carrier density (ns) was calculated for each temperature (above and below Tc) and the results confirmed the existence of ns at temperatures above Tc. The observed real superconducting condensate (ns) above Tc puts a serious constraint on the theory for high- Tc superconductivity. A theory based on an inhomogeneous superconducting state, in which a microscopically phase-separated state in a doped Mott insulator can be observed, is the most plausible candidate. This theory can explain the existence of ns and the observed temperature range for the precursor superconducting state. The results obtained show that the pseudogap coexists with superconductivity below Tc and is not the precursor of superconductivity. On the other hand, it is also possible to define a precursor superconducting state that is different than the pseudogap. The temperature range and the observed superconducting condensate in this state can be explained with the help of the inhomogeneous superconducting state.
Pseudogenes
by Laura PolisenoProviding a list of methods useful both to those who wish to study pseudogenes and to those who actually want to avoid their inadvertent detection, Pseudogenes: Functions and Protocols explores techniques involving pseudogenic DNA, RNA, and peptides/proteins, once believed to lack any functionality, but now known to be involved in complex regulatory circuits. After a few introductory chapters that overview the functions so far attributed to pseudogenes, this thorough volume delves into methods for pseudogene identification, for the detection of pseudogene transcription and translation, and for the study of the functions of pseudogenic RNA and proteins, as well as methods to avoid pseudogene detection when the focus of the research is their highly homologous parental counterparts. As part of the highly successful Methods in Molecular Biology series, chapters feature the kind of detailed descriptions and implementation advice that ensures successful results in the lab. Authoritative and practical, Pseudogenes: Functions and Protocols will contribute to the high interest of the scientific community toward pseudogenes, while stimulating the conception of pseudogene - centered research projects and providing experimental protocols that can facilitate their execution.
Pseudomonas: Molecular and Applied Biology
by Rachhpal S. KahlonThis book provides a conciseand comprehensive overview of the basic biology, genomics, biotechnologicalapplications and role of Pseudomonas in agriculture, environment andindustry. The Pseudomonas genus occupies a key position in medicine, theenvironment, agriculture and commercial biotechnology by virtue of its geneticdiversity, metabolic adaptability and versatility and the broad array ofecological niches that it inhabits. Pseudomonas aeruginosa, anopportunistic pathogen, is known for its multiple drug resistance and isassociated with cystic fibrosis and wound infections particularly in patientswith burn injuries. Pseudomonas syringae is a plant pathogen andis responsible for major crop losses in horticultural, vegetable and fieldcrops. Another species, P. fluorescens is known for promoting plantgrowth through the production of certain hormones and the biocontrol ofsoil-borne fungal diseases and insects. The ability to adapt to diverseand challenging environments and degrade recalcitrant compounds means that thegenus is widely exploited for bioremediation, while their genetic diversitycoupled with broad catalytic potential makes them valuable inbiotransformation, synthesis of high-value chiral compounds for biosynthesisand production of biopolymers and bio-surfactants widely used in medicine,agriculture and industry. The book serves as a readyreference and text book for graduate students, young field microbiologists andresearch scientists in academia, research institutes andindustry.
Pseudomonas
by Juan L. Ramos Alain FillouxThe five previous volumes of Pseudomonas series covered the biology of pseudomonads in a wide context, including the niches they inhabit, the taxonomic relations among members of this group, the molecular biology of gene expression in different niches and under different environmental conditions, the analysis of virulence traits in plants, animals and human pathogens as well as the determinants that make some strains useful for biotechnological applications and promotion of plant growth. Pseudomonas volume 6 is intended to collect new information on molecular microbiology, infection and biodiversity. This sixth volume covers the following topics: transcription regulation, virulence control, physiology and metabolism, bacteriology, microbial genetics and genomics. Pseudomonas volume 6 will be of use to researchers working on these bacteria, particularly those studying genomics, physiology, quorum sensing, life styles, metabolism etc. Advanced students in biology, medicine and agronomy will also find this volume a valuable reference during their studies.
Pseudomonas
by Juan-Luis Ramos Johanna B. Goldberg Alain FillouxPseudomonas volume 7 collects some of the most relevant and emerging issues in the biology of these microorganisms, and a number of other important issues that were not collected in the previous volumes. The first six volumes of the Pseudomonas series covered the biology of pseudomonads in a wide range of contexts, including the niches they inhabit, the taxonomic relations among its members of this group, the molecular biology of gene expression in different niches and under different environmental conditions, the analysis of virulence in plants, animal and human pathogens, as well as the determinants that make some of these strains of interesting for biotechnological applications. This seventh volume covers the following topics: The history of the biology of Pseudomonas The use of Pseudomonas as biological agents New trends in the molecular biology of these microorganisms Pseudomonas and the immune system of insects and animals This book will be of use to researchers working on these bacteria, particularly those studying medical aspects of Pseudomonas, and their use as a means to control pathogens or to stimulate plant growth. This volume is also interesting for those studying the physiology, genetics, molecular biology of Pseudomonas and those using novel-omics approaches to understand bacteria of the genus Pseudomonas.
Pseudomonas aeruginosa: Methods and Protocols (Methods in Molecular Biology #2721)
by Giovanni Bertoni Silvia FerraraThis book aims to provide methods, protocols, and discussion topics for those who wish to examine in depth the molecular mechanisms of adaptation and versality of bacteria and would like to envisage their evolution responses in the fast changing Antropocene.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Pseudomonas aeruginosa: Methods and Protocols aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
Pseudomonas aeruginosa: Biology, Pathogenesis and Control Strategies (Advances in Experimental Medicine and Biology #1386)
by Alain Filloux Juan-Luis RamosThis book covers the wide set of well-regulated virulence factors and defense mechanisms of Pseudomonas aeruginosa focusing on stress responses and the evolution of this opportunistic human pathogen. Pseudomonas aeruginosa is responsible for one out of ten hospital infections. Additionally, this Gram-negative bacterium is accountable for persistent infections in immunocompromised individuals and the leading cause of chronic lung infections in cystic fibrosis patients. This book provides insight on the metabolic versatility of Pseudomonas aeruginosa and its mechanisms for biofilm formation that make this organism highly efficient in causing infections. The book invites the readers to learn more about the intrinsic ability of Pseudomonas aeruginosa to resist a wide variety of antimicrobial agents due to the concerted action of multidrug efflux pumps, antibiotic-degrading enzymes, and the low permeability of bacterial cellular envelopes. Particular focus is put on the evolutionary role of different types of protein-secretion systems in pathogenesis, flagella and their role in chemotaxis and surface sensing, and host-pathogen interactions. This book is a useful introduction to the field for junior scientists interested in the biology and pathogenesis of Pseudomonas aeruginosa. It is also an interesting read for advanced scientists and medical specialists working within this field, providing a broader view of the topic beyond their specific area of specialization.
Pseudomonas Methods and Protocols: Methods And Protocols (Methods in Molecular Biology #1149)
by Juan-Luis Ramos Alain FillouxIn Pseudomonas aeruginosa, expert researchers in the field detail many of the methods which are now commonly used to study this fascinating microorganism. Chapters include microbiological methods to high-throughput molecular techniques that have been developed over the last decade. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Pseudomonas aeruginosa aids in the continuing study of new and cutting edge findings.
Pseudoscience: The Conspiracy Against Science (The\mit Press Ser.)
by Allison B. Kaufman James C. KaufmanCase studies, personal accounts, and analysis show how to recognize and combat pseudoscience in a post-truth world.In a post-truth, fake news world, we are particularly susceptible to the claims of pseudoscience. When emotions and opinions are more widely disseminated than scientific findings, and self-proclaimed experts get their expertise from Google, how can the average person distinguish real science from fake? This book examines pseudoscience from a variety of perspectives, through case studies, analysis, and personal accounts that show how to recognize pseudoscience, why it is so widely accepted, and how to advocate for real science. Contributors examine the basics of pseudoscience, including issues of cognitive bias; the costs of pseudoscience, with accounts of naturopathy and logical fallacies in the anti-vaccination movement; perceptions of scientific soundness; the mainstream presence of “integrative medicine,” hypnosis, and parapsychology; and the use of case studies and new media in science advocacy.ContributorsDavid Ball, Paul Joseph Barnett, Jeffrey Beall, Mark Benisz, Fernando Blanco, Ron Dumont, Stacy Ellenberg, Kevin M. Folta, Christopher French, Ashwin Gautam, Dennis M. Gorman, David H. Gorski, David K. Hecht, Britt Marie Hermes, Clyde F. Herreid, Jonathan Howard, Seth C. Kalichman, Leif Edward Ottesen Kennair, Arnold Kozak, Scott O. Lilienfeld, Emilio Lobato, Steven Lynn, Adam Marcus, Helena Matute, Ivan Oransky, Chad Orzel, Dorit Reiss, Ellen Beate Hansen Sandseter, Kavin Senapathy, Dean Keith Simonton, Indre Viskontas, John O. Willis, Corrine Zimmerman
Pseudoscience and Science Fiction
by Andrew MayAliens, flying saucers, ESP, the Bermuda Triangle, antigravity . . . are we talking about science fiction or pseudoscience? Sometimes it is difficult to tell the difference. Both pseudoscience and science fiction (SF) are creative endeavours that have little in common with academic science, beyond the superficial trappings of jargon and subject matter. The most obvious difference between the two is that pseudoscience is presented as fact, not fiction. Yet like SF, and unlike real science, pseudoscience is driven by a desire to please an audience - in this case, people who "want to believe". This has led to significant cross-fertilization between the two disciplines. SF authors often draw on "real" pseudoscientific theories to add verisimilitude to their stories, while on other occasions pseudoscience takes its cue from SF - the symbiotic relationship between ufology and Hollywood being a prime example of this. This engagingly written, well researched and richly illustrated text explores a wide range of intriguing similarities and differences between pseudoscience and the fictional science found in SF. Andrew May has a degree in Natural Sciences from Cambridge University and a PhD in astrophysics from Manchester University. After many years in academia and the private sector, he now works as a freelance writer and scientific consultant. He has written pocket biographies of Newton and Einstein, as well as contributing to a number of popular science books. He has a lifelong interest in science fiction, and has had several articles published in Fortean Times magazine
Pseudoscience - The Conspiracy Against Science
by Allison Kaufman James Kaufman David Hecht Emilio Lobato Corrine ZimmermanIn a post-truth, fake news world, we are particularly susceptible to the claims of pseudoscience. When emotions and opinions are more widely disseminated than scientific findings, and self-proclaimed experts get their expertise from Google, how can the average person distinguish real science from fake? This book examines pseudoscience from a variety of perspectives, through case studies, analysis, and personal accounts that show how to recognize pseudoscience, why it is so widely accepted, and how to advocate for real science. Contributors examine the basics of pseudoscience, including issues of cognitive bias; the costs of pseudoscience, with accounts of naturopathy and logical fallacies in the anti-vaccination movement; perceptions of scientific soundness; the mainstream presence of “integrative medicine,” hypnosis, and parapsychology; and the use of case studies and new media in science advocacy.
The Pseudoscience Wars: Immanuel Velikovsky and the Birth of the Modern Fringe
by Michael D. GordinProperly analyzed, the collective mythological and religious writings of humanity reveal that around 1500 BC, a comet swept perilously close to Earth, triggering widespread natural disasters and threatening the destruction of all life before settling into solar orbit as Venus, our nearest planetary neighbor. Sound implausible? Well, from 1950 until the late 1970s, a huge number of people begged to differ, as they devoured Immanuel Velikovsky’s major best-seller, Worlds in Collision, insisting that perhaps this polymathic thinker held the key to a new science and a new history. Scientists, on the other hand, assaulted Velikovsky’s book, his followers, and his press mercilessly from the get-go. In The Pseudoscience Wars, Michael D. Gordin resurrects the largely forgotten figure of Velikovsky and uses his strange career and surprisingly influential writings to explore the changing definitions of the line that separates legitimate scientific inquiry from what is deemed bunk, and to show how vital this question remains to us today. Drawing on a wealth of previously unpublished material from Velikovsky’s personal archives, Gordin presents a behind-the-scenes history of the writer’s career, from his initial burst of success through his growing influence on the counterculture, heated public battles with such luminaries as Carl Sagan, and eventual eclipse. Along the way, he offers fascinating glimpses into the histories and effects of other fringe doctrines, including creationism, Lysenkoism, parapsychology, and more—all of which have surprising connections to Velikovsky’s theories. Science today is hardly universally secure, and scientists seem themselves beset by critics, denialists, and those they label “pseudoscientists”—as seen all too clearly in battles over evolution and climate change. The Pseudoscience Wars simultaneously reveals the surprising Cold War roots of our contemporary dilemma and points readers to a different approach to drawing the line between knowledge and nonsense.
Pseudotyped Viruses (Advances in Experimental Medicine and Biology #1407)
by Youchun WangThis book intends to report the new progress of pseudotyped viruses, including the construction of pseudotyped viruses with different strategies or vectors for most important viruses. Especially for emerging viruses, optimization of the condition and parameters for assay development based on the pseudotyped viruses and widely application as surrogate of authentic virus to study the biological functions of virus, detection of neutralizing antibody, screening viral entry inhibiters, and others. It includes most pseudotyped viruses that have the protein of the target virus on the surface of the parent virus with incomplete genome. The book is likely to be of interest to all researchers in the field of virology, vaccine, and anti-viral drug development and evaluation.
Psicologia e psichiatria antiche: per il mondo moderno
by Farhad PourgolafshanQuando si parla di scienze mediche antiche prevalgono incomprensioni e confusione. Si afferma che tutto sia una cura di questo o quello. In questa confusione molti opportunisti, i quali includono anche alcuni medici, guadagnano molto e velocemente. Alla fine, sono i consumatori e i malati che pagano le conseguenze di queste circostanze. Questo libro cerca di stabilire dei punti di riferimento per l’identificazione e la valutazione delle scienze mediche antiche in generale e di psicologia e psichiatria antiche e dei loro trattamenti specifici in particolare, in maniera da aiutare a minimizzare la confusione attuale. Il libro contiene un esame dettagliato della storia delle scienze antiche e moderne, come richiesto per comprendere la situazione attuale. Come esempio vengono fornite descrizioni accurate di trattamenti antichi della medicina tradizionale cinese (MTC) di alcuni disturbi psicologici. Viene presentata anche una discussione estesa circa la teoria evoluzionista, il darwinismo e il progressismo, considerati gli eventi storici che hanno contribuito maggiormente ad instaurare la situazione attuale.
Psicologia e Psiquiatria Antiga para o Mundo Moderno: Ciência Antiga versus Moderna
by Farhad PourgolafshanQuando se trata de antigas ciências médicas, os mal-entendidos e a confusão prevalecem. Diz-se que tudo e qualquer coisa são a cura para isto ou aquilo. Nessa confusão, muitos oportunistas, incluindo alguns médicos, estão obtendo grandes ganhos rapidamente. Em última análise, são os consumidores e os doentes os maiores perdedores nessas circunstâncias. Este livro está a tentar estabelecer alguns pontos de referência para a identificação e avaliação das ciências médicas antigas em geral, e da psicologia e psiquiatria antiga em particular, e os seus tratamentos específicos, a fim de ajudar a minimizar a confusão atual. Há um tratamento detalhado da história das ciências antigas e modernas, pois é necessário para a compreensão da situação atual. Como exemplos, os antigos tratamentos da medicina tradicional chinesa (MTC) para alguns distúrbios psicológicos são fornecidos com alguma profundidade. Há também uma ampla discussão sobre a Teoria da Evolução, o Darwinismo e o Progressivismo como pano de fundo histórico que leva à situação atual.
Psicología y Psiquiatría Antigua: Para el Mundo Moderno
by Dr Farhad Pour-GolafshanCuando se trata de ciencias médicas antiguas, prevalecen los malentendidos y la confusión. Se afirma que todo y cualquier cosa es la cura para esto o aquello. En medio de esta confusión, muchos oportunistas, incluidos algunos médicos, están logrando grandes ganancias, rápidamente. Por ejemplo, son los consumidores y los enfermos los que más pierden en dichas circunstancias. Este libro intenta establecer algunos puntos de referencia para la identificación y evaluación de las ciencias médicas antiguas en general y para la psicología y la psiquiatría antiguas, en particular. Además, se examinan algunos de sus tratamientos específicos, para ayudar a mitigar la actual confusión. Existe una aproximación específica en la historia de las ciencias, tanto antiguas como modernas, ya que este es necesario para comprender la situación actual. Como ejemplos, podemos citar los tratamientos antiguos de la Medicina Tradicional China (MTC) para algunos trastornos psicológicos los cuales se proporcionan en algunas instituciones, añadiéndose además una extensa discusión sobre la teoría evolucionista, el darwinismo y el progresismo como antecedentes históricos que causaron, aparentemente, la confusa situación en la actualidad.
Psilocybin Mushrooms of the World: An Identification Guide
by Paul StametsFrom the author of GROWING GOURMET AND MEDICINAL MUSHROOMS comes the only identification guide exclusively devoted to the world's psilocybin-containing mushrooms. Detailed descriptions and color photographs for over 100 species are provided, as well as an exploration of their long-standing (and often religious) use by ancient peoples and their continued significance to modern-day culture. Some of the species included have just been discovered in the past year or two, and still others have never before been photographed in their natural habitats.
Psocids as Global Pests of Stored Products
by Edited by Christos G. Athanassiou, Manoj K. NayakPsocids have become widespread pests of stored products during the last two decades, yet little was known about their biology and management until this change in their pest status. The aim of this book is to synthesize current information on biology and management of these stored-product insect pests. The book covers their identification, biology and ecology, monitoring, chemical and non-chemical control, resistance to insecticides, molecular biology, and the future of stored-product psocid research. This is the first-ever comprehensive book on Psocids infesting stored products and is written by a carefully selected list of experts on these pests. It is essential reading for all those involved in the control of pests in stored products and postharvest systems, students and researchers in applied entomology and pest management practitioners in general.
Psoralen Dna Photobiology: Volume I
by Francis P. GasparroIn one form or another psoralens have been in use dating back to biblical times for the treatment of depigmented patches of skin. However, it has only been in the past 40 years that the structure and function of psoralens have been elucidated. Although several volumes have been published on photobiology and photomedicine, no one volume has ever been devoted to the psoralen photobiology. In these two volumes we focus on the properties and uses of photoactivated psoralens.In these volumes the various aspects of psoralens are presented in a review of the field as it stands in mid 1986. In retrospect, we may find that this particular time was crucial in the development of new therapeutic modalities as many of the applications of modem molecular biology are beginning to impact on the practice of medicine.This book was written with two purposes in mind. First, to serve as an update (the last collective review of the field was in 1982). Second, it is hoped that newcomers to the fields of photobiology andphotomedicine both scientists and clinicians would find it a useful introduction.
Psoralen Dna Photobiology: Volume II
by Francis P. GasparroIn one form or another psoralens have been in use dating back to biblical times for the treatment of depigmented patches of skin. However, it has only been in the past 40 years that the structure and function of psoralens have been elucidated. Although several volumes have been published on photobiology and photomedicine, no one volume has ever been devoted to the psoralen photobiology. In these two volumes we focus on the properties and uses of photoactivated psoralens.In these volumes the various aspects of psoralens are presented in a review of the field as it stands in mid 1986. In retrospect, we may find that this particular time was crucial in the development of new therapeutic modalities as many of the applications of modem molecular biology are beginning to impact on the practice of medicine.This book was written with two purposes in mind. First, to serve as an update (the last collective review of the field was in 1982). Second, it is hoped that newcomers to the fields of photobiology andphotomedicine both scientists and clinicians would find it a useful introduction.
PSPICE and MATLAB for Electronics: An Integrated Approach, Second Edition (VLSI Circuits)
by John Okyere AttiaUsed collectively, PSPICE and MATLAB are unsurpassed for circuit modeling and data analysis. PSPICE can perform DC, AC, transient, Fourier, temperature, and Monte Carlo analysis of electronic circuits with device models and subsystem subcircuits. MATLAB can then carry out calculations of device parameters, curve fitting, numerical integration, nume
Psych: The Story of the Human Mind
by Paul BloomA Next Big Idea Club Must-ReadA compelling and accessible new perspective on the modern science of psychology, based on one of Yale’s most popular courses of all timeHow does the brain—a three-pound wrinkly mass—give rise to intelligence and conscious experience? Was Freud right that we are all plagued by forbidden sexual desires? What is the function of emotions such as disgust, gratitude, and shame? Renowned psychologist Paul Bloom answers these questions and many more in Psych, his riveting new book about the science of the mind.Psych is an expert and passionate guide to the most intimate aspects of our nature, serving up the equivalent of a serious university course while being funny, engaging, and full of memorable anecdotes. But Psych is much more than a comprehensive overview of the field of psychology. Bloom reveals what psychology can tell us about the most pressing moral and political issues of our time—including belief in conspiracy theories, the role of genes in explaining human differences, and the nature of prejudice and hatred.Bloom also shows how psychology can give us practical insights into important issues—from the treatment of mental illnesses such as depression and anxiety to the best way to lead happy and fulfilling lives. Psych is an engrossing guide to the most important topic there is: it is the story of us.
Psyche and Matter
by Marie-Louise von FranzTwelve essays by the distinguished analyst Marie-Louise von Franz--five of them appearing in English for the first time--discuss synchronicity, number and time, and contemporary areas of rapprochement between the natural sciences and analytical psychology with regard to the relationship between mind and matter. This last question is among the most crucial today for fields as varied as microphysics, psychosomatic medicine, biology, quantum physics, and depth psychology.
Psychedelic Psychiatry: LSD from Clinic to Campus
by Erika DyckLSD's short but colorful history in North America carries with it the distinct cachet of counterculture and government experimentation. The truth about this mind-altering chemical cocktail is far more complex—and less controversial—than generally believed. Psychedelic Psychiatry is the tale of medical researchers working to understand LSD’s therapeutic properties just as escalating anxieties about drug abuse in modern society laid the groundwork for the end of experimentation at the edge of psychopharmacology. Historian Erika Dyck deftly recasts our understanding of LSD to show it as an experimental substance, a medical treatment, and a tool for exploring psychotic perspectives—as well as a recreational drug. She recounts the inside story of the early days of LSD research in small-town, prairie Canada, when Humphry Osmond and Abram Hoffer claimed incredible advances in treating alcoholism, understanding schizophrenia and other psychoses, and achieving empathy with their patients. In relating the drug’s short, strange trip, Dyck explains how concerns about countercultural trends led to the criminalization of LSD and other so-called psychedelic drugs—concordantly opening the way for an explosion in legal prescription pharmaceuticals—and points to the recent re-emergence of sanctioned psychotropic research among psychiatric practitioners. This challenge to the prevailing wisdom behind drug regulation and addiction therapy provides a historical corrective to our perception of LSD’s medical efficacy.