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The Stockholm Paradigm: Climate Change and Emerging Disease

by Daniel R. Brooks Eric P. Hoberg Walter A. Boeger

The contemporary crisis of emerging disease has been a century and a half in the making. Human, veterinary, and crop health practitioners convinced themselves that disease could be controlled by medicating the sick, vaccinating those at risk, and eradicating the parts of the biosphere responsible for disease transmission. Evolutionary biologists assured themselves that coevolution between pathogens and hosts provided a firewall against disease emergence in new hosts. Most climate scientists made no connection between climate changes and disease. None of these traditional perspectives anticipated the onslaught of emerging infectious diseases confronting humanity today. As this book reveals, a new understanding of the evolution of pathogen-host systems, called the Stockholm Paradigm, explains what is happening. The planet is a minefield of pathogens with preexisting capacities to infect susceptible but unexposed hosts, needing only the opportunity for contact. Climate change has always been the major catalyst for such new opportunities, because it disrupts local ecosystem structure and allows pathogens and hosts to move. Once pathogens expand to new hosts, novel variants may emerge, each with new infection capacities. Mathematical models and real-world examples uniformly support these ideas. Emerging disease is thus one of the greatest climate change–related threats confronting humanity. Even without deadly global catastrophes on the scale of the 1918 Spanish Influenza pandemic, emerging diseases cost humanity more than a trillion dollars per year in treatment and lost productivity. But while time is short, the danger is great, and we are largely unprepared, the Stockholm Paradigm offers hope for managing the crisis. By using the DAMA (document, assess, monitor, act) protocol, we can “anticipate to mitigate” emerging disease, buying time and saving money while we search for more effective ways to cope with this challenge.

Stoelting's Anesthesia And Co-existing Disease

by Roberta L. Hines Katherine Marschall

With Stoelting's Anesthesia and Co-Existing Disease, you'll have the succinct, yet thorough guidance you need to successfully avoid or manage complications stemming from pre-existing medical conditions. Advanced research from experts in the field will help you overcome the toughest challenges in practice, letting you offer your patients the best care, each and every time. Deliver anesthesia as safely as possible with extensive coverage of the pathophysiology of numerous coexisting conditions. Effectively manage special patient populations with a focus on pediatric, geriatric, and adult patients. Master the ins and outs of a wide range of diseases, from common to rare, through detailed discussions of each disease's unique features.

Stoff- und Formleichtbau: Leichter Einstieg mit eindimensionalen Strukturen

by Andreas Öchsner

Dieses Lehrbuch stellt die unterschiedlichen Leichtbaukonzepte anhand einfacher eindimensionaler Strukturen in sehr verständlicher Weise dar und ermöglicht einen leichten Einstieg in das Thema. Es werden nachvollziehbare Informationen und Hinweise zur Werkstoffauswahl und geometrischen Gestaltung von Bauteilen gegeben.

Stoffliche Nutzung von Braunkohle

by Steffen Krzack Heiner Gutte Bernd Meyer

Das Fachbuch beschäftigt sich mit Braunkohle als einheimischer Energierohstoff mit hohem Nutzungspotential für die chemische Industrie, die Metallurgie und andere Wirtschaftszweige. Der komplexe Aufbau dieses Naturprodukts ist einerseits eine große Herausforderung für dessen Verarbeitung, erlaubt andererseits aber auch eine große Bandbreite der stofflichen Wertschöpfung.Ausgehend von Grundlagen und Verfahren der stofflichen Braunkohlenutzung werden Forschungsergebnisse zu neuen Analysemethoden, zu grundlegenden prozess- und werkstofftechnischen Untersuchungen, zu neuen Ansätzen für Verfahrens- und Komponentenentwicklungen sowie zu neu geschaffenen Modellierungs- und Simulationswerkzeugen vorgestellt. Die Einzelthemen sind entlang der Wertschöpfungskette vom Rohstoff zum Produkt, auch unter Einbeziehung von Biomasse als nachwachsendem Energierohstoff, strukturiert.

Stomp Rockets, Catapults, and Kaleidoscopes: 30+ Amazing Science Projects You Can Build for Less than $1

by Curt Gabrielson

Kids will learn how things they encounter every day operate by building their own models with this hands-on activity book. Projects include building a working model of the human hand's muscles, bones, and tendons using drinking straws, tape, and string; using a pair of two-liter bottles and a length of rubber tubing to learn how a toilet flushes; and discovering how musical instruments make sounds by fashioning a harmonica, saxophone, drum, flute, or oboe. All devices are designed to use recycled or nearly free materials and common tools. Kids are encouraged to modify and improve the designs, or create an entirely new device using the concepts explored. Each project includes materials and tools lists, step-by-step instructions with photographs, a summary of the science concept demonstrated, and follow-up questions to gauge student understanding for use in the classroom.

Stone Cladding Engineering

by Rui de Sousa Camposinhos

This volume presents new methodologies for the design of dimension stone based on the concepts of structural design while preserving the excellence of stonemasonry practice in façade engineering. Straightforward formulae are provided for computing action on cladding, with special emphasis on the effect of seismic forces, including an extensive general methodology applied to non-structural elements. Based on the Load and Resistance Factor Design Format (LRDF), minimum slab thickness formulae are presented that take into consideration stress concentrations analysis based on the Finite Element Method (FEM) for the most commonly used modern anchorage systems. Calculation examples allow designers to solve several anchorage engineering problems in a detailed and objective manner, underlining the key parameters. The design of the anchorage metal parts, either in stainless steel or aluminum, is also presented.

Stone Tools and Fossil Bones: Debates in the Archaeology of Human Origins

by Manuel Domínguez-Rodrigo

The stone tools and fossil bones from the earliest archaeological sites in Africa have been used over the past fifty years to create models that interpret how early hominins lived, foraged, behaved, and communicated, and how early and modern humans evolved. In this book, an international team of archaeologists and primatologists examines early Stone Age tools and bones and uses scientific methods to test alternative hypotheses that explain the archaeological record. By focusing on both lithics and faunal records, this volume presents the most holistic view to date of the archaeology of human origins.

Stone Tools in Human Evolution

by Shea John J.

In Stone Tools in Human Evolution, John J. Shea argues that over the last three million years hominins' technological strategies shifted from occasional tool use, much like that seen among living non-human primates, to a uniquely human pattern of obligatory tool use. Examining how the lithic archaeological record changed over the course of human evolution, he compares tool use by living humans and non-human primates and predicts how the archaeological stone tool evidence should have changed as distinctively human behaviors evolved. Those behaviors include using cutting tools, logistical mobility (carrying things), language and symbolic artifacts, geographic dispersal and diaspora, and residential sedentism (living in the same place for prolonged periods). Shea then tests those predictions by analyzing the archaeological lithic record from 6,500 years ago to 3. 5 million years ago.

The Stones and the Stars

by Duncan Lunan

There are at least 48 identified prehistoric stone circles in Scotland. In truth, very little is known about the people who erected them, and ultimately about what the stone circles were for. Most stone circles are astronomically aligned, which has led to the modern debate about why the alignment was significant. The megaliths certainly represented an enormous co-operative effort, would at the very least have demonstrated power and wealth, and being set away from any dwellings probably served a ceremonial, or perhaps religious, purpose. Observations at the site of the stone circles, of solar, lunar, and stellar events, have already cast light on some of the questions about the construction and use of ancient megalithic observatories. In his capacity as manager of the Parks Department Astronomy Project, author Duncan Lunan designed and built the first astronomically aligned stone circle in Britain in over 3,000 years. 'The Stones and the Stars' examines the case for astronomical alignments of stone circles, and charts the development of a fascinating project with a strong scientific and historical background. The work was documented in detail by the artist and photographer Gavin Roberts, and this archive has been added to since - so an appropriate selection of illustrations will bring the project vividly to life.

Stop Gaining Weight The Easy Way: How to maintain a healthy body and mind (Stop... The Easy Way)

by Dr Mike Dilkes Alexander Adams

The world does not need another diet book. But what it does need, is a book that explains how to achieve and maintain a stable, healthy weight.With easy-to-understand chapters, focused firstly on why it is so easy to gain weight, and then how to effectively keep it off; this is an essential guide for anyone looking to take control of their weight in a safe and sustainable way.Combining their expert guidance with practical and accessible tips for making a change today, Dr Mike Dilkes and Alex Adams share the many life-changing reasons why we shouldn't be focusing on how to lose weight but instead, how to stop gaining it.

Stop Gaining Weight The Easy Way: How to maintain a healthy body and mind (Stop... The Easy Way)

by Dr Mike Dilkes Alexander Adams

The world does not need another diet book. But what it does need, is a book that explains how to achieve and maintain a stable, healthy weight.With easy-to-understand chapters, focused firstly on why it is so easy to gain weight, and then how to effectively keep it off; this is an essential guide for anyone looking to take control of their weight in a safe and sustainable way.Combining their expert guidance with practical and accessible tips for making a change today, Dr Mike Dilkes and Alex Adams share the many life-changing reasons why we shouldn't be focusing on how to lose weight but instead, how to stop gaining it.

Stop the Germs! (Health and My Body)

by Mari Schuh

Yuck, germs! Germs can make us sick. How do we stay healthy? With engaging text and colorful photos, readers find out how to keep the germs away. Stop the Germs! includes a glossary, read more section, kid-friendly internet sites, and an index.

Stop What You’re Doing and Read…Books That Changed the World: The Origin of Species & The Communist Manifesto

by Charles Darwin Karl Marx Friedrich Engels

To mark the publication of Stop What You're Doing and Read This!, a collection of essays celebrating reading, Vintage Classics are releasing 12 limited edition themed ebook 'bundles', to tempt readers to discover and rediscover great books. THE ORIGIN OF SPECIES & THE VOYAGE OF THE BEAGLE INTRODUCED BY DARWIN'S GREAT GREAT GRANDDAUGHTER RUTH PADELWhen the eminent naturalist Charles Darwin returned from South America on board the H.M.S Beagle in 1836, he brought with him the notes and evidence which would form the basis of his landmark theory of evolution of species by a process of natural selection. This theory, published as The Origin of Species in 1859, is the basis of modern biology and the concept of biodiversity. It also sparked a fierce scientific, religious and philosophical debate which still continues today.THE COMMUNISTY MANIFESTOINTRODUCED BY DAVID AARONOVITCHThe Communist Manifesto was first published in London, by two young men in their late twenties, in 1848. Its impact reverberated across the globe and throughout the next century, and it has come to be recognised as one of the most important political texts ever written. Maintaining that the history of all societies is a history of class struggle, the manifesto proclaims that communism is the only route to equality, and is a call to action aimed at the proletariat. It is an essential read for anyone seeking to understand our modern political landscape.

Stop Working & Start Thinking

by Jack Cohen Graham Medley

With the spectacular developments in technology accompanying and aiding scientific research over the past few decades, postgraduate students are often encouraged to focus more on generating data than to utilize their most sophisticated piece of equipment: their mind.Stop Working & Start Thinking, Second Edition aims to encourage young researchers to think more clearly about their experiments, from experimental design to data interpretation. This new edition builds on the success of the first edition, with new material throughout and a new chapter on measurement interpretation, including an examination of cryptic assumptions.This book is essential reading for postgraduates who wish to put the mastery back into their M.Sc. and the philosophy back into their PhDs.

Stopping Climate Change: Policies for Real Zero (Routledge Studies in Environmental Policy)

by Paul Ekins

Written by one of the leading experts in the field, Paul Ekins, Stopping Climate Change provides a comprehensive overview of what is required to achieve ‘real zero’ carbon dioxide emissions by 2050, and negative emissions thereafter, which is the only way to stop human- induced climate change.This will require innovation in socio-technical systems, and in human behaviour, on an unprecedented scale. Stopping Climate Change describes the changes required to meet this goal: in technologies, social institutions and individual activities. Paul Ekins examines in detail issues around the supply and demand of energy and materials, and the efficiency of their use. It also analyses greenhouse gas removal technologies, offsetting and geoengineering, and plots the reduction of the non- CO2 greenhouse gas-emitting activities. Having set out the changes required, Ekins considers the economic implications, in terms of both the innovation and investments that are necessary to bring them about, and the effects that these are likely to have on national economies. The evidence presented points clearly to the economic impacts of decarbonisation being positive for the majority of countries, and for the world as a whole, even before considering the benefits of avoided climate change. When the health benefits of stopping the burning of fossil fuels are factored in, the global net benefits of decarbonisation are unequivocal.Drawing on examples from the UK and Europe, but with wider relevance at a global scale, Stopping Climate Change clearly shows how determined policy action at different levels could stop climate change. It will be of great interest to students, scholars and policymakers researching and working in the field of climate change and energy policy.

Stopping Gender-based Violence in Higher Education: Policy, Practice, and Partnerships

by Clarissa J. Humphreys Graham J. Towl

Stopping Gender-based Violence in Higher Education provides a unique insight into how gender-based violence at universities is impacting students and staff and outlines the path toward tangible changes that can prevent it. Bringing together perspectives from academics, activists, practitioners, and university administrators, the book presents a diverse range of voices to constructively critique the field. Structured in three parts, the book begins by addressing the context, theory, and law that stipulates how universities can effectively respond to reports of gender-based violence. It goes on to discuss the most pragmatic ways to address the issue while contributing to prevention and supporting victim-survivors. Finally, the book advocates for the development of beneficial working partnerships with key external services available to university communities and also working with students as partners in an ethical and safe way. Throughout the book, contributors are invited to demonstrate a comprehensive institution-wide and trauma-informed approach to centre the needs of the victim-survivor and prioritize resources to undertake this vital work. Each chapter ends with a brief summary of key points or recommendations and suggested further reading on the chapter topic. Although the authors draw on research and policy from the UK Higher Education sector, the insights will be a useful resource for those in universities around the world. This book is an essential reference point and resource for professionals, academics, and students in Higher Education, as well as indispensable reading for activists, policymakers, police, rape crisis groups, and other organisations supporting these universities who want to make meaningful change in reducing, responding to, and preventing gender-based violence in Higher Education.

Stopping the Next Pandemic: How Covid-19 Can Help Us Save Humanity

by Debora MacKenzie

'Excellent . . . analyses clearly and authoritatively how the coronavirus pandemic played out, what governments should have done, and what we need to do when it happens again - as it undoubtedly will' Financial Times'You could not hope for a better guide to the pandemic world order than Debora MacKenzie, who's been on this story from the start. This is an authoritative yet readable explanation of how this catastrophe happened - and more important, how it will happen again if we don't change'Tim Harford, author of The Undercover Economist, Adapt and Messy'This definitely deserves a read - the first of the post mortems by a writer who knows what she's talking about'Laura Spinney, author of Pale Rider: The Spanish Flu of 1918 and How It Changed the WorldIn a gripping, accessible narrative, a veteran science journalist lays out the shocking story of how the COVID-19 coronavirus pandemic happened and how to make sure this never happens againOver the last 30 years of epidemics and pandemics, we learned every lesson needed to stop this coronavirus outbreak in its tracks. We heeded almost none of them. The result is a pandemic on a scale never before seen in our lifetimes. In this captivating, authoritative, and eye-opening book, science journalist Debora MacKenzie lays out the full story of how and why it happened: the previous viruses that should have prepared us, the shocking public health failures that paved the way, the failure to contain the outbreak, and most importantly, what we must do to prevent future pandemics.Debora MacKenzie has been reporting on emerging diseases for more than three decades, and she draws on that experience to explain how COVID-19 went from a potentially manageable outbreak to a global pandemic. Offering a compelling history of the most significant recent outbreaks, including SARS, MERS, H1N1, Zika, and Ebola, she gives a crash course in Epidemiology 101--how viruses spread and how pandemics end--and outlines the lessons we failed to learn from each past crisis. In vivid detail, she takes us through the arrival and spread of COVID-19, making clear the steps that governments knew they could have taken to prevent or at least prepare for this. Looking forward, MacKenzie makes a bold, optimistic argument: this pandemic might finally galvanize the world to take viruses seriously. Fighting this pandemic and preventing the next one will take political action of all kinds, globally, from governments, the scientific community, and individuals--but it is possible.No one has yet brought together our knowledge of COVID-19 in a comprehensive, informative, and accessible way. But that story can already be told, and Debora MacKenzie's urgent telling is required reading for these times and beyond. It is too early to say where the COVID-19 pandemic will go, but it is past time to talk about what went wrong and how we can do better.

Storage Ring-Based Inverse Compton X-ray Sources: Cavity Design, Beamline Development and X-ray Applications (Springer Theses)

by Benedikt Sebastian Günther

This thesis presents research on novel laboratory-scale synchrotron X-ray sources based on inverse Compton scattering and applications of their X-ray radiation using the Munich Compact Light Source (MuCLS) as an example. It provides an introduction to the theory of this laser-electron interaction, laser resonators and X-ray interactions with matter. On this basis, upgrades to the laser system including the development of a new laser optic, X-ray beam stabilisation and two techniques for fast X-ray energy switching of inverse Compton sources are presented. On the application side, the beamline, designed and developed for the inverse Compton X-ray source at the MuCLS, is described before various techniques and applications are demonstrated at this laboratory-scale synchrotron X-ray facility. Among them are K-edge subtraction imaging, X-ray phase contrast imaging and X-ray absorption spectroscopy. Additionally, a new X-ray microscopy technique, called full-field structured-illumination super-resolution X-ray transmission microscopy, is presented.Apart from research conducted at the MuCLS, this thesis contains an in-depth overview on the state of the art of the various types of inverse Compton X-ray sources that have been realised so far. Accordingly, this thesis may serve as a guide and reference work for researchers working with inverse Compton X-ray sources as well as future users of such devices.

Store-operated Ca2+ entry (SOCE) pathways

by Klaus Groschner Wolfgang Graier Christoph Romanin

Store-operated Ca2+ entry (SOCE) serves to control essential functions throughout the human body and represents a novel and attractive target for therapeutic intervention. This book provides an extensive overview of the role of SOCE pathways in Molecular Physiology and Cell Biology, as well as their clinical significance. (Patho)physiological principles and emerging therapeutic strategies are delineated in a way that is valuable both for the education of graduate students in advanced Cell Biology/Molecular Physiology and for the promotion of innovative research and developments in the clinical/therapeutic fields. A comprehensive, clear and elaborate representation of current concepts is provided, including a pathophysiological section arranged in a tissue/organ/system-oriented manner. The book is intended for basic researchers specializing in cell signaling, ion transport, or pharmacology, as well as biomedical scientists and clinicians with a focus on immunology, neurology or cardiology.

Stories and the Brain: The Neuroscience of Narrative

by Paul B. Armstrong

This book explains how the brain interacts with the social world--and why stories matter. How do our brains enable us to tell and follow stories? And how do stories affect our minds? In this book, the author analyzes the cognitive processes involved in constructing and exchanging stories, exploring their role in the neurobiology of mental functioning. Taking up the age-old question of what our ability to tell stories reveals about language and the mind, this truly interdisciplinary project should be of interest to humanists and cognitive scientists alike.

Stories, Dice, and Rocks That Think: How Humans Learned to See the Future--and Shape It

by Byron Reese

". . . Byron Reese gets to the heart of what makes humans different from all others." —Midwest Book ReviewWhat makes the human mind so unique? And how did we get this way?This fascinating tale explores the three leaps in our history that made us what we are—and will change how you think about our future.Look around. Clearly, we humans are radically different from the other creatures on this planet. But why? Where are the Bronze Age beavers? The Iron Age iguanas? In Stories, Dice, and Rocks That Think, Byron Reese argues that we owe our special status to our ability to imagine the future and recall the past, escaping the perpetual present that all other living creatures are trapped in. Envisioning human history as the development of a societal superorganism he names Agora, Reese shows us how this escape enabled us to share knowledge on an unprecedented scale, and predict—and eventually master—the future.Thoughtful, witty, and compulsively readable, Reese unravels our history as an intelligent species in three acts: Act I: Ancient humans undergo &“the awakening,&” developing the cognitive ability to mentally time-travel using languageAct II: In 17th century France, the mathematical framework known as 'probability theory' is born—a science for seeing into the future that we used to build the modern worldAct III: Beginning with the invention of the computer chip, humanity creates machines to gaze into the future with even more precision, overcoming the limits of our brainsA fresh new look at the history and destiny of humanity, readers will come away from Stories, Dice, and Rocks that Think with a new understanding of what they are—not just another animal, but a creature with a mastery of time itself.

Stories for Boys Who Dare to Be Different 2: Even More True Tales of Amazing Boys Who Changed the World (The Dare to Be Different Series)

by Ben Brooks

Boys can be anything they want to be! In this sequel to the New York Times bestseller Stories for Boys Who Dare to Be Different, Ben Brooks introduces seventy-six more boys and men who will inspire young readers to live boldly and true to themselves.What do environmental activist Xiuhtezcatl Martinez, philosopher Socrates, and singer Ed Sheeran all have in common? Each of them defied expectations -- going against the grain and pursuing their dreams despite a seemingly impossible barrage of obstacles and difficulties. Their stories are incredible, as are those of tap dancer Evan Ruggiero, Pokémon creator Satoshi Tajiri, the brave Chernobyl Divers, and the other inspirational boys who fill the pages of this extraordinary book.Together, their stories offer young boys the welcome alternative message that masculinity can mean many things -- that it's okay to be sensitive, to be bold, and to follow their hearts.

Stories from the Skeleton: Behavioral Reconstruction in Human Osteology (Interpreting The Remains Of The Past Ser. #Vol. 1.)

by Robert Jurmain

"First Published in 1999, Routledge is an imprint of Taylor & Francis, an informa company."

Stories in the Stars

by Hannah Waldron Susanna Hislop

A beautifully illustrated Penguin Hardcover that invites readers to travel the night sky and discover the universe of stories in the stars To those who can decipher it, the night sky is alive with gods and goddesses, animals and mythical creatures--an endless carnival played out in shining constellations. Amidst this jet-black canvas pricked with white dots, a hunter leaps in pursuit with his dogs at his heels, a sea monster threatens a maiden in distress, and a pair of twins lives forever.In Stories in the Stars, writer and stargazer Susanna Hislop and international artist Hannah Waldron present an imaginative journey through the heavens. Leaping between centuries, cultures, and traditions, they explore each of the night sky's eighty-eight constellations through gorgeous illustrations and vivid descriptions that will linger in readers' minds long after they've closed the book and stepped outside on a starry night.

Stories of Astronomers and Their Stars (The Patrick Moore Practical Astronomy Series)

by David E. Falkner

This book recounts the stories of the astronomical pioneers who forever changed our views of the cosmos. The chapters delve into their fascinating lives over the centuries, showing how these pivotal minds built upon the work of their predecessors and unlocked the unique properties of specific stars. From ancient astronomy to modern imaging and spectroscopy, each tale at once showcases the pace of scientific discovery and the shared passions that drove these starwatchers. Accompanying the stories are a plethora of constellation and finder charts, stellar coordinates and directions, and suggestions for viewing specific stars, all of which are visible to the naked eye or through a small telescope. In addition, the histories on specific star names and designations are given, along with an overview of the most popular catalogues and online databases that readers can use for reference.

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Showing 66,651 through 66,675 of 76,016 results