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Structure and Method in Aristotle's Meteorologica
by Malcolm WilsonIn the first full-length study in any modern language dedicated to the Meteorologica, Malcolm Wilson presents a groundbreaking interpretation of Aristotle's natural philosophy. Divided into two parts, the book first addresses general philosophical and scientific issues by placing the treatise in a diachronic frame comprising Aristotle's predecessors and in a synchronic frame comprising his other physical works. It argues that Aristotle thought of meteorological phenomena as intermediary or 'dualizing' between the cosmos as a whole and the manifold world of terrestrial animals. Engaging with the best current literature on Aristotle's theories of science and metaphysics, Wilson focuses on issues of aetiology, teleology and the structure and unity of science. The second half of the book illustrates Aristotle's principal concerns in a section-by-section treatment of the meteorological phenomena and provides solutions to many of the problems that have been raised since the time of the ancient commentators.
Structure and Organic Matter Storage in Agricultural Soils
by M.R. Carter B.A. StewartSoils comprise the largest pool of terrestrial carbon and therefore are an important component of carbon storage in the biosphere-atmosphere system. Structure and Organic Matter Storage in Agricultural Soils explores the mechanisms and processes involved in the storage and sequestration of carbon in soils. Focusing on agricultural soils - from tropical to semi-arid types - this new book provides an in-depth look at structure, aggregation, and organic matter retention in world soils. The first two sections of the book introduce readers to the basic issues and scientific concepts, including soil structure, underlying mechanisms and processes, and the importance of agroecosystems as carbon regulators. The third section provides detailed discussions of soil aggregation and organic matter storage under various climates, soil types, and soil management practices. The fourth section addresses current strategies for enhancing organic matter storage in soil, modelling techniques, and measurement methods.Throughout the book, the importance of the soil structure-organic matter storage relationship is emphasized. Anyone involved in soil science, agriculture, agronomy, plant science, or greenhouse gas and global change studies should understand this relationship. Structure and Organic Matter Storage in Agricultural Soils provides an ideal source of information not only on the soil structure-storage relationship itself, but also on key research efforts and direct applications related to the storage of organic matter in agricultural soils.
Structure and Physics of Viruses
by Mauricio G. MateuThis book contemplates the structure, dynamics and physics of virus particles: From the moment they come into existence by self-assembly from viral components produced in the infected cell, through their extracellular stage, until they recognise and infect a new host cell and cease to exist by losing their physical integrity to start a new infectious cycle. (Bio)physical techniques used to study the structure of virus particles and components, and some applications of structure-based studies of viruses are also contemplated. This book is aimed first at M.Sc. students, Ph.D. students and postdoctoral researchers with a university degree in biology, chemistry, physics or related scientific disciplines who share an interest or are actually working on viruses. We have aimed also at providing an updated account of many important concepts, techniques, studies and applications in structural and physical virology for established scientists working on viruses, irrespective of their physical, chemical or biological background and their field of expertise. We have not attempted to provide a collection of for-experts-only reviews focused mainly on the latest research in specific topics; we have not generally assumed that the reader knows all of the jargon and all but the most recent and advanced results in each topic dealt with in this book. In short, we have attempted to write a book basic enough to be useful to M.Sc and Ph.D. students, as well as advanced and current enough to be useful to senior scientists with an interest in Structural and/or Physical Virology.
Structure and Properties of Cell Membrane Structure and Properties of Cell Membranes: Volume III (Structure And Properties Of Cell Membranes Ser.)
by BengaThis book provides in-depth presentations in membrane biology by specialists of international repute. The volumes examine world literature on recent advances in understanding the molecular struc-ture and properties of membranes, the role they play in cellular physiology and cell-cell interactions, and the alterations leading to abnormal cells. Illustrations, tables, and useful appendices com-plement the text. Those professionals actively working in the field of cell membrane investigations as well as biologists, biochemists, biophysicists, physicians, and academicians, will find this work beneficial.
Structure and Properties of Cell Membrane Structure and Properties of Cell Membranes: Volume II (Structure And Properties Of Cell Membranes Ser.)
by BengaThis book provides in-depth presentations in membrane biology by specialists of international repute. The volumes examine world literature on recent advances in understanding the molecular struc-ture and properties of membranes, the role they play in cellular physiology and cell-cell interactions, and the alterations leading to abnormal cells. Illustrations, tables, and useful appendices com-plement the text. Those professionals actively working in the field of cell membrane investigations as well as biologists, biochemists, biophysicists, physicians, and academicians, will find this work beneficial.
Structure and Properties of Cell Membrane Structure and Properties of Cell Membranes: Volume I (Structure And Properties Of Cell Membranes Ser.)
by BengaThis book provides in-depth presentations in membrane biology by specialists of international repute. The volumes examine world literature on recent advances in understanding the molecular struc-ture and properties of membranes, the role they play in cellular physiology and cell-cell interactions, and the alterations leading to abnormal cells. Illustrations, tables, and useful appendices com-plement the text. Those professionals actively working in the field of cell membrane investigations as well as biologists, biochemists, biophysicists, physicians, and academicians, will find this work beneficial.
Structure and Properties of Conducting Polymer Composites
by V.E. GulThe development of the principles of electrically conductive polymer composites and the creation of a wide variety of such materials have had a significant influence on modern technology. This volume in the "New Concepts in Polymer Science" series is devoted to various aspects of the structure and properties of electrically conductive polymer composites. This monograph is an attempt to systematize modern ideas on the interconnection of the structure and properties of ECPCs. Specific attention is given to the influence of electric current on kinetics and the direction of chemical interactive processes between such systems and air oxygen. The book also contains a special chapter which is devoted to the practical applications of electrically conductive polymer composites. It should be of use and interest to researchers working in the field.
Structure and Properties of Fat Crystal Networks
by Alejandro G. Marangoni Leendert H. WesdorpLipid science and technology has grown exponentially since the turn of the millennium. The replacement of unhealthy fats in the foods we eat, and of petroleum-based ingredients in the cosmetics we use, is a top priority for consumers, government, and industry alike. Particularly for the food industry, removing trans fats and reducing saturated fat
Structure and Properties of Liquid Crystals
by Lev M. BlinovThis book introduces the most important concepts related to the structure and physical properties of liquid crystals, including some of the theoretical aspects. It consists of three parts: structure, physical properties, and electro-optic behavior.
Structure and Properties of Matter
by Janette SchusterMatter, States of Matter, Physical Properties of Matter, Mixtures, Physical and Chemical Changes, Conserving Matter, Science and Engineering Practices, Careers.
Structure and Properties of Matter Journal
by Battle CenterStudents explore matter in terms of measurable properties and as made up of particles too small to be seen. Students develop an understanding that the number of particles and weight of matter does not change regardless of the changes it goes through.
Structure and Reactions of Light Exotic Nuclei
by Yasuyuki Suzuki Kazuhiro Yabana Rezso G. Lovas Kalman VargaSince the mid-1980s increasing effort has been put into light exotic nuclei, that is light nuclei of unusual composition. The research of the exotic nuclei began with the advent of accelerated beams of such nuclei. This new technique has revitalized nuclear physics, and the facilities producing radioactive ion beams now offer opportunities for pion
Structure-Based Drug Design
by Pandi VeerapandianIntroducing the most recent advances in crystallography, nuclear magnetic resonance, molecular modeling techniques, and computational combinatorial chemistry, this unique, interdisciplinary reference explains the application of three-dimensional structural information in the design of pharmaceutical drugs. Furnishing authoritative analyses by world-renowned experts, Structure-Based Drug Design discusses protein structure-based design in optimizing HIV protease inhibitors and details the biochemical, genetic, and clinical data on HIV-1 reverse transcriptase presents recent results on the high-resolution three-dimensional structure of the catalytic core domain of HIV-1 integrase as a foundation for divergent combination therapy focuses on structure-based design strategies for uncovering receptor antagonists to treat inflammatory diseases demonstrates a systematic approach to the design of inhibitory compounds in cancer treatment reviews current knowledge on the Interleukin-1 (IL-1) system and progress in the development of IL-1 modulators describes the influence of structure-based methods in designing capsid-binding inhibitors for relief of the common cold and much more!
Structure-Based Drug Discovery
by Leslie W. TariThe last decade has seen the confluence of several enabling technologies that have allowed protein crystallographic methods to live up to their true potential. Taken together, the numerous recent advances have made it possible to tackle difficult biological targets with a high probability of success: intact bacterial ribosomes have been structurally elucidated, as well as eukaryotic trans-membrane proteins like the potassium channel and GPCRs. It is now possible for medicinal chemists to have access to structural information on their latest small molecule candidates bound to the therapeutic target within days of compound synthesis, allowing structure guided ligand optimization to occur in "real time". Structure-Based Drug Discovery presents an array of methods used to generate crystal structures of biological macromolecules, how to leverage the structural information to design novel ligands anew, and how to iteratively optimize hits and convert them to leads. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Structure-Based Drug Discovery aims to provide scientists interested in adding SBDD to their arsenal of drug discovery methods with well-honed, up-to-date methodologies.
Structure, Bonding and Reactivity of Heterocyclic Compounds
by Frank Proft Paul GeerlingsThe series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.
The Structure Dependent Energy of Organic Compounds (SpringerBriefs in Molecular Science)
by Árpád FurkaThis brief introduces readers to an alternative thermochemical reference system that makes it possible to use the heats of formation of organic compounds to deduce the energies that depend entirely on their structures, and which provides calculated values for most of the characteristic structures appearing in organic molecules. These structure-dependent energies are provided e.g. for selected compounds of normal and cyclic alkanes, open chain and cyclic olefins (including conjugated polyenes), alkynes, aromatic hydrocarbons and their substituted derivatives. The oxygen, sulfur and nitrogen derivatives of the above-mentioned compounds are also represented with calculated structure-dependent energies including alcohols, ethers, aldehydes and ketones, carboxylic acids, thiols, sulfides, amines, amides, heterocyclic compounds and others. Most organic reactions can be interpreted as the disappearance of certain structures and formation of others. If the structure-dependent energies are known, it can be shown how the disappearing and the newly formed structures contribute to the heat of reactions and to the driving forces. As experienced by the author, who pioneered the concept, structure dependent energies can help teachers to make organic chemistry more accessible for their students. Accordingly, the brief offers a valuable resource for all those who teach organic chemistry at universities, and for those who are learning it.
Structure Determination By Spectroscopic Methods: A Practical Approach
by Raul SanMartin Maria Teresa HerreroThe authors travel with the reader through the challenging maze of structure determination, showing how to distinguish between valuable and deceiving data from IR, NMR and MS spectra, extracting structural conclusions and putting all the pieces together to solve the structure elucidation puzzle. Indeed, human reasoning is key to combining the information contained in those bands, signals and peaks by a rationale that enables the makeup of a chemical structure. A number of increasingly more complex problems will act as trip segments and, in addition to the spectra themselves, each chapter is supplemented with figures and tables that decipher the above data and serve as maps for the journey.
Structure Determination by X-ray Crystallography
by Mark Ladd Rex PalmerThe advances in and applications of x-ray and neutron crystallography form the essence of this new edition of this classic textbook, while maintaining the overall plan of the book that has been well received in the academic community since the first edition in 1977. X-ray crystallography is a universal tool for studying molecular structure, and the complementary nature of neutron diffraction crystallography permits the location of atomic species in crystals which are not easily revealed by X-ray techniques alone, such as hydrogen atoms or other light atoms in the presence of heavier atoms. Thus, a chapter discussing the practice of neutron diffraction techniques, with examples, broadens the scope of the text in a highly desirable way. As with previous editions, the book contains problems to illustrate the work of each chapter, and detailed solutions are provided. Mathematical procedures related to the material of the main body of the book are not discussed in detail, but are quoted where needed with references to standard mathematical texts. To address the computational aspect of crystallography, the suite of computer programs from the fourth edition has been revised and expanded. The programs enable the reader to participate fully in many of the aspects of x-ray crystallography discussed in the book. In particular, the program system XRAY* is interactive, and enables the reader to follow through, at the monitor screen, the computational techniques involved in single-crystal structure determination, albeit in two dimensions, with the data sets provided. Exercises for students can be found int the book, and solutions are available to instructors.
Structure Determination of HIV-1 Tat/Fluid Phase Membranes and DMPC Ripple Phase Using X-Ray Scattering
by Kiyotaka AkaboriThis Thesis in biological physics has two components, describing the use of X-ray scattering techniques to study the structure of two different stacked lipid membrane systems. The first part focuses on the interaction between a short 11-mer peptide, Tat, which is part of the Tat protein in the HIV-1 virus. Although highly positively charged, the Tat protein has been shown to translocate through hydrocarbon lipid bilayers easily, without requiring the cell's energy, which is counter to its Born self-energy. In this work Tat's location in the headgroup region was demonstrated using a combined X-ray scattering and molecular dynamics approach. Bilayer thinning was observed as well as softening of different membrane mimics due to Tat. It was concluded that Tat's headgroup location, which increases the area/lipid, and its bilayer softening likely reduce the energy barrier for passive translocation. The second part is a rigorous investigation of an enigmatic phase in the phase diagram of the lipid dimyristoylphosphatidylcholine (DMPC). The ripple phase has fascinated many researchers in condensed matter physics and physical chemistry as an example of periodically modulated phases, with many theoretical and simulation papers published. Despite systematic studies over the past three decades, molecular details of the structure were still lacking. By obtaining the highest resolution X-ray data so far, this work revealed the complex nature of the chain packing, as well as confirming that the major side is thicker than the minor side of the saw-tooth ripple structure. The new model shows that the chains in the major arm are tilted with respect to the bilayer normal and that the chains in the minor arm are slightly more disordered than all-trans gel-phase chains, i. e. , the chains in the minor arm are more fluid-like. This work provides the highest resolution X-ray structure of the ripple phase to-date.
Structure Elucidation in Organic Chemistry
by Maria-Magdalena Cid Jorge BravoIntended for advanced readers, this is a review of all relevant techniques for structure analysis in one handy volume. As such, it provides the latest knowledge on spectroscopic and related techniques for chemical structure analysis, such as NMR, optical spectroscopy, mass spectrometry and X-ray crystallography, including the scope and limitation of each method. As a result, readers not only become acquainted with the techniques, but also the advantages of the synergy between them. This enables them to choose the correct analytical method for each problem, saving both time and resources. Special emphasis is placed on NMR and its application to absolute configuration determination and the analysis of molecular interactions. Adopting a practical point of view, the author team from academia and industry guarantees both solid methodology and applications essential for structure determination, equipping experts as well as newcomers with the tools to solve any structural problem.
Structure, Evidence, and Heuristic: Evolutionary Biology, Economics, and the Philosophy of Their Relationship (Routledge Studies in the Philosophy of Science)
by Armin W. SchulzThis book is the first systematic treatment of the philosophy of science underlying evolutionary economics. It does not advocate an evolutionary approach towards economics, but rather assesses the epistemic value of appealing to evolutionary biology in economics more generally. The author divides work in evolutionary economics into three distinct, albeit related, forms: a structural form, an evidential form, and a heuristic form. He then analyzes five examples of work in evolutionary economics falling under these three forms. For the structural form, he examines the parallelism between natural selection and economic decision making, and the parallelism between natural selection and market competition. For the evidential form, he looks at the relationship between animal and human economic decision making, and the evolutionary explanation of diversity in human economic decision making. Finally, for the heuristic form, he focuses on the plausibility of equilibrium modeling in evolutionary ecology and economics. In this way, he shows that linking evolutionary biology and economics can make for a powerful methodological tool that can enable progress in our understanding of various economics questions. Structure, Evidence, and Heuristic will be of interest to scholars and advanced students working in philosophy of science, philosophy of social science, evolutionary biology, and economics.
Structure Formation in Modified Gravity Cosmologies
by Alexandre BarreiraThis unique thesis covers all aspects oftheories of gravity beyond Einstein's General Relativity, from setting up theequations that describe the evolution of perturbations, to determining thebest-fitting parameters using constraints like the microwave backgroundradiation, and ultimately to the later stages of structure formation usingstate-of-the-art N-body simulations and comparing them to observations ofgalaxies, clusters and other large-scale structures. This truly ground-breakingwork puts the study of modified gravity models on the same footing as thestandard model of cosmology. Since the discovery of the accelerating expansionof the Universe, marked by the awarding of the 2011 Nobel Prize in Physics,there has been a growing interest in understanding what drives thatacceleration. One possible explanation lies in theories of gravity beyondEinstein's General Relativity. This thesis addresses all aspects of the problem,an approach that is crucial to avoiding potentially catastrophic biases in theinterpretation of upcoming observational missions.
Structure & Function of the Body 13th Edition
by Gary A. Thibodeau Kevin T. PattonThis textbook concentrates on the normal structures and function of the human body and on what the body does to maintain homeostasis. Chapters discuss topics like biochemistry, cells and tissue, the various organ systems, the senses, blood, immunity, nutrition and metabolism, fluid and electrolyte balance, acid-base balance, and growth and development. Approximately 330 color illustrations and cadaver photographs visually represent the anatomy under discussion. Thibodeau taught biology at the University of Wisconsin-River Falls. Patton teaches life sciences at Saint Charles Community College. Annotation ©2004 Book News, Inc. , Portland, OR (booknews. com)