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The Dynamic Nature of Mitochondria: from Ultrastructure to Health and Disease (Oxidative Stress and Disease)
by Andreas S. ReichertMitochondrial research has exploded over the last ~150 years. This book gives an amazing view on a conceptual change in our understanding of mitochondrial biology. It becomes clear that mitochondria are extremely dynamic in nature, controlling life at multiple levels. Mitochondria rule energy conversion, adapt cells well to changing stress and nutrient conditions, and regulate many cellular processes including immunity. The dynamic nature of mitochondria occurs at an intramitochondrial level but also includes its ability to interact with other organelles and to modulate multiple signalling pathways. It is thus not surprising that alterations or inabilities to ensure this dynamic behaviour is linked to ageing and human diseases.The following sections give an updated view on mitochondria: Mitochondrial ultrastructure: molecular mechanisms shaping the inner membrane Mitochondrial cristae and lipid dynamics: from super-resolution microscopy to lipid-OXPHOS interplay Mitochondrial control of cellular homeostasis: from redox signalling to interorganellar contact sites Mitochondria in health and disease: from mtDNA release to Complex I assembly Advanced methods in mitochondrial biology and metabolism research Integrative view on mitochondrial research and outlook The field of mitochondrial research has always been full of surprises and has helped science to advance tremendously. It developed hand in hand with landmark developments in technology, such as super-resolution microscopy (nanoscopy), and is currently influencing an increasing number of scientific disciplines. There is still much ‘new’ to find out about this ‘old’ organelle and I think that you can find interesting and also unexpected aspects of mitochondrial biology in this book. I hope the book will enhance your scientific curiosity and inspire your own research.
The Dynamic Synapse: Molecular Methods in Ionotropic Receptor Biology (Frontiers in Neuroscience)
by Josef T. Kittler Stephen J. MossExploring the diverse tools and technologies used to study synaptic processes, The Dynamic Synapse: Molecular Methods in Ionotropic Receptor Biology delineates techniques, methods, and conceptual advances for studying neurotransmitter receptors and other synaptic proteins. It describes a broad range of molecular, biochemica
The Dynamic Terrorist Threat: An Assessment of Group Motivations and Capabilities in a Changing World
by Cheryl Y. Marcum Sara A. Daly Kim Cragin M. Rebecca Kilburn Susan S. Everingham Jill HoubeAs the war on terrorism wages on, our nation's policymakers will continue to face the challenge of assessing threats that various terrorist groups pose to the U.S. homeland and our interests abroad. As part of the RAND Corporation's yearlong "Thinking Strategically About Combating Terrorism" project, the authors of this report develop a way to assess and analyze the danger posed by various terrorist organizations around the world. The very nature of terrorism creates a difficulty in predicting new and emerging threats; however, by establishing these types of parameters, the report creates a fresh foundation of threat analysis on which future counterterrorism strategy may build.
The Dynamical Projectors Method: Hydro and Electrodynamics
by Sergey Leble Anna PerelomovaThe dynamical projectors method proves to reduce a multicomponent problem to the simplest one-component problem with its solution determined by specific initial or boundary conditions. Its universality and application in many different physical problems make it particularly useful in hydrodynamics, electrodynamics, plasma physics, and boundary layer problems. A great variety of underlying mechanisms are included making this book useful for those working in wave theory, hydrodynamics, electromagnetism, and applications. "The authors developed a universal and elegant tool – dynamical projector method. Using this method for very complicated hydro-thermodynamic and electrodynamics problem settings, they were able to get a lot of interesting analytical results in areas where before often just numerical methods were applicable." —L. A. Bordag, University of Applied Sciences Zittau/Görlitz, Zittau, Germany "The book is intended for professionals working in various fields of linear and nonlinear mathematical physics, partial differential equations and theoretical physics. The book is written clearly, and in my opinion, its material will be useful and easy to understand for professionals and for students familiar with ordinary and partial differential equations." —Sergey Dobrokhotov, Russian Academy of Sciences, Moscow, Russia
The Dynamics and Mechanism of Human Thermal Adaptation in Building Environment: A Glimpse to Adaptive Thermal Comfort in Buildings (Springer Theses)
by Maohui LuoThis book focuses on human adaptive thermal comfort in the building environment and the balance between reducing building air conditioning energy and improving occupants’ thermal comfort. It examines the mechanism of human thermal adaptation using a newly developed adaptive heat balance model, and presents pioneering findings based on an on online survey, real building investigation, climate chamber experiments, and theoretical models. The book investigates three critical issues related to human thermal adaptation: (i) the dynamics of human thermal adaptation in the building environment; (ii) the basic rules and effects of human physiological acclimatization and psychological adaptation; and (iii) a new, adaptive, heat balance model describing behavioral adjustment, physiological acclimatization, psychological adaptation, and physical improvement effects. Providing the basis for establishing a more reasonable adaptive thermal comfort model, the book is a valuable reference resource for anyone interested in future building thermal environment evaluation criteria.
The Dynamics of Agricultural Change: The Historical Experience (Routledge Library Editions: Agriculture #10)
by David GriggFirst published in 1982. Until the nineteenth-century the history of agriculture was the history of mankind but it has not perhaps received the wide attention that this importance justifies. In this study, the author reviews for the student of agricultural history successive attempts to describe and explain agricultural changes that are not specific to a limited area or a particular time. In a sense The Dynamics of Agricultural Change is a systematic historical geography of agriculture. Some of the models the author explores have been developed within agricultural history; some, drawn from other disciplines, can be applied fruitfully to it. What is the relationship between population growth and agricultural development? Between environmental changes and those in agriculture? What was the effect of the industrial revolution? And has there been an agricultural revolution? This book suggests to university students of economic history, historical geography and agriculture, a number of stimulating ways of interpreting and reinterpreting agricultural history.
The Dynamics of Biological Systems (Mathematics of Planet Earth #4)
by Mark A. Lewis Thomas Hillen Yingfei Yi Arianna BianchiThe book presents nine mini-courses from a summer school, Dynamics of Biological Systems, held at the University of Alberta in 2016, as part of the prestigious seminar series: Séminaire de Mathématiques Supérieures (SMS). It includes new and significant contributions in the field of Dynamical Systems and their applications in Biology, Ecology, and Medicine. The chapters of this book cover a wide range of mathematical methods and biological applications. They - explain the process of mathematical modelling of biological systems with many examples, - introduce advanced methods from dynamical systems theory, - present many examples of the use of mathematical modelling to gain biological insight- discuss innovative methods for the analysis of biological processes,- contain extensive lists of references, which allow interested readers to continue the research on their own. Integrating the theory of dynamical systems with biological modelling, the book will appeal to researchers and graduate students in Applied Mathematics and Life Sciences.
The Dynamics of Cultural Evolution: The Central Role of Purposive Behaviors (Studies in Human Ecology and Adaptation #12)
by Michael RosenbergThis book explores the nature of cultural and culturally structured social and behavioral entities, their evolutionary interactions, and the central role purposive behaviors play in those interactions. It, first, makes the case for cultural and cultural structured systems being considered as true entities bounded in time and space, and not ephemera in a constant state of becoming another system. Second, it examines how these entities interact to produce evolutionary culture change. It then argues that the intent of purposive behaviors is reliably knowable in the aggregate, at least when dealing with expressions of behavioral tendencies in the animal kingdom, humans included. Finally, the book references well documented behavioral tendencies for examples of proximate causation in the evolution of settled village societies and, following that, socially complex societies. Through these efforts, the book synthesizes the various approaches to the evolution of culture and provides a complete and comprehensive picture of the process. It provides a corrective to the tendency to view cultural systems as entirely open ended and as capable of changing in any direction; and also to treating cultural evolution as solely a result of selective forces, that is, in terms of only ultimate causation. This book provides an engaging and critical counterview to established theories of cultural evolution and is of interest to scholars and students of different disciplines, from anthropology and archeology, to evolutionary biology and epigenetics.
The Dynamics of Discrete Populations and Series of Events
by Keith Iain Hopcraft Eric Jakeman Kevin D. RidleyDiscrete phenomena are an important aspect of various complex systems, acting both as underlying driving mechanisms and as manifestations of diverse behaviours. However, the characterisation of these discrete phenomena requires models that go beyond those featured in existing books. Largely concerned with mathematical models used to describe time-v
The Dynamics of Electrons in Linear Plasma Devices and Its Impact on Plasma Surface Interaction (Springer Theses)
by Michael HubenyTurbulence in plasma surface interaction holds crucial uncertainties for its impact on material erosion in the operation of fusion reactors. In this thesis, the design, development and operation of a Thomson scattering diagnostic and its novel implementation with fast visual imaging created a versatile tool to investigate intermittently occuring plasma oscillations. Specifically, ballistic transport events in the plasma edge, constituting turbulent transport, have been targeted in this thesis. With the help of a custom photon counting algorithm, the conditional averaging technique was applied on Thomson scattering for the first time to allow spatial and pseudo-time-resolved measurements.Since plasma turbulence and the emerging transport phenomena are comparable in most magnetized devices, the diagnostic development and the results from the linear plasma device PSI-2 are useful for an implementation of similar techniques in larger fusion experiments. Furthermore, the obtained results indicate a strong enhancement of erosion with turbulent transport and thus underline the importance of dedicated experiments investigating plasma turbulence in the framework of erosion in future fusion reactors.
The Dynamics of Energy: Supply, Conversion, and Utilization
by Horacio Perez-BlancoAs mankind searches for energy alternatives with minimal environmental consequences and acceptable cost, it is necessary to identify valid areas of endeavor that can activate favorable energy sources and technological developments. Toward that end, The Dynamics of Energy: Supply, Conversion, and Utilization develops competence in energy matters on
The Dynamics of Environmental and Economic Systems: Innovation, Environmental Policy and Competitiveness
by Massimiliano Mazzanti Valeria CostantiniExploiting econometric techniques aimed at dealing with the dynamics of economic systems and the heterogeneity of agents performances, the volume integrates innovation-based reasoning with ex-post analyses, and presents ex-ante analyses able to evaluate the role of climate change policies by using computable general equilibrium models such as the Global Trade Analysis Project for Energy (GTAP-E). The authors merge and use a range of datasets, including OECD-PATSTAT and STAN, to test novel techniques informed by evolutionary economic theories and the Porter hypothesis. The immediate relevance and applicability of the models will strengthen the hand of policy analysts for whom the dynamic efficiency of environmental policy is a new, high-profile evaluation criterion.
The Dynamics of Front Propagation in Nonlocal Reaction–Diffusion Equations (Lecture Notes on Mathematical Modelling in the Life Sciences)
by Jean-Michel RoquejoffreThe book provides a self-contained and complete description of the long time evolution of the solutions to a class of one-dimensional reaction–diffusion equations, in which the diffusion is given by an integral operator. The underlying motivation is the mathematical analysis of models for biological invasions. The model under study, while simple looking, is of current use in real-life situations. Interestingly, it arises in totally different contexts, such as the study of branching random walks in probability theory. While the model has attracted a lot of attention, and while many partial results about the time-asymptotic behaviour of its solutions have been proved over the last decades, some basic questions on the sharp asymptotics have remained unanswered. One ambition of this monograph is to close these gaps. In some of the situations that we envisage, the level sets organise themselves into an invasion front that is asymptotically linear in time, up to a correction that converges exponentially in time to a constant. In other situations that constitute the main and newest part of the work, the correction is asymptotically logarithmic in time. Despite these apparently different behaviours, there is an underlying common way of thinking that is underlined. At the end of each chapter, a long set of problems is proposed, many of them rather elaborate and suitable for master's projects or even the first question in a PhD thesis. Open questions are also discussed. The ideas presented in the book apply to more elaborate systems modelling biological invasions or the spatial propagation of epidemics. The models themselves may be multidimensional, but they all have in common a mechanism imposing the propagation in a given direction; examples are presented in the problems that conclude each chapter. These ideas should also be useful in the treatment of further models that we are not able to envisage for the time being. The book is suitable for graduate or PhD students as well as researchers.
The Dynamics of Murder: Kill or Be Killed
by R. Barri FlowersIn recent years, there has been a surge in school shootings, workplace homicides, hate violence, and deadly terrorist attacks in the United States. This has resulted in a greater focus on homicidal behavior, its antecedents, ways to recognize warning signs of at-risk victims and offenders, and preventive measures. It has also led to increased effor
The Dynamics of Small Solar System Bodies (SpringerBriefs in Astronomy)
by Jeremy WoodThis SpringerBrief summarizes the latest relevant research and discoveries that have been made in the area of ringed small bodies and small body taxonomy, including those that lay the groundwork for future discoveries. Before 2013, ringed small bodies were only theoretical. Thus, there are very limited publications available on this relatively new subfield of astronomy. With the introduction of the GAIA catalogue, star positions are now known better than ever before. Since rings are discovered through the use of starlight occultation, we could very well be looking at an explosion of discoveries of ringed small bodies in the near future. Each chapter is accompanied by exercises, and an end-of-book answer key is provided. As such, this brief will benefit students and researchers alike who wish to have a single document and quick access to the latest information on ringed small bodies and small body taxonomy.
The Dynamics of Vehicles on Roads
by A.H. WickensFirst published in 1982. CRC Press is an imprint of Taylor & Francis.
The Dyslexic Advantage (New Edition): Unlocking the Hidden Potential of the Dyslexic Brain
by Brock L. Eide Fernette F. EideA MAJOR REVISION WITH BRAND-NEW MATERIAL. Discover how the unique strengths of dyslexia can be channelled for success at home, school and work with this ground-breaking exploration of the dyslexic brain.In this paradigm-shifting book, neuro-learning experts Dr Brock L. Eide and Dr Fernette F. Eide describe a new brain science revealing that people with dyslexia have unique brain structure and organization. While the differences are responsible for challenges with literacy and reading, the dyslexic brain also gives a predisposition to important skills and special talents. This transformational new edition includes:- significantly updated chapters on the neurobiology underlying dyslexia and dyslexic strengths- ground-breaking science and interviews with successful dyslexics and innovative teachersWith much-needed prescriptive advice for parents, educators, co-workers and dyslexics, The Dyslexic Advantage provides a new framework to create a fuller, more balanced and more useful model of dyslexia. The authors of this essential book show how the unique strengths of dyslexia can lead to amazing success.
The Dyslexic Advantage (Revised and Updated): Unlocking the Hidden Potential of the Dyslexic Brain
by Brock L. Eide Fernette F. EideAn updated edition of Drs. Brock and Fernette Eide's popular dyslexia book with a wealth of new material and improved dyslexic-friendly font. What if we viewed dyslexia as a learning and processing style rather than as a learning disorder? Drs. Brock and Fernette Eide use their impressive backgrounds in neurology and education to debunk the standard deficit-based approach to dyslexia. People typically define &“dyslexia&” as a reading and spelling disorder. But through published research studies, clinical observations, and interviews with dyslexic individuals, the Eides prove that these challenges are not dyslexia&’s main features but are instead trade-offs resulting from an entirely different pattern of brain organization and information processing that has powerful advantages. For example, dyslexic adults routinely outperform their non-dyslexic peers in studies on three-dimensional spatial reasoning and divergent creativity—one of the reasons why so many dyslexics are successful engineers. Approximately 20 percent of the U.S. population has dyslexia, and The Dyslexic Advantage shows how each one is predisposed to powerful skills called MIND strengths (Material, Interconnected, Narrative, and Dynamic Reasoning), leading them to possess incredible pattern detection, divergent thinking, episodic memory, problem solving, and prediction abilities. The revised and updated edition of The Dyslexic Advantage includes eighteen rich new profiles of remarkable individuals with dyslexia—such as several world-renowned scientists, a Pulitzer Prize–winning poet, a world-record-setting memory specialist, three MacArthur &“Genius&” Award winners, the technical advisor for the Jurassic Park movies, and many more. Meanwhile, the enormous advances in dyslexia research over the last ten years provide valuable new insights for educators, employers, parents, dyslexic adults, and anyone interested in neurodiversity and human cognition. Blending personal stories with hard science, The Dyslexic Advantage (Revised and Updated) provides empowering advice on how to identify, understand, nurture, and enjoy the strengths of the dyslexic mind.
The Dyslexic Advantage: Unlocking the Hidden Potential of the Dyslexic Brain
by Brock L. Eide Fernette F. EideTwo neurolearning experts reveal the hidden benefits of having a dyslexic brain. In this paradigm-shifting book, neurolearning experts Drs. Brock and Fernette Eide describe an exciting new brain science that reveals that dyslexic people have unique brain structure and organization. While the differences are responsible for certain challenges with literacy and reading, the dyslexic brain also gives a predisposition to important skills, and special talents. While dyslexics typically struggle to decode the written word, they often also excel in such areas of reasoning as mechanical (required for architects and surgeons), interconnected (artists and inventors); narrative (novelists and lawyers), and dynamic (scientists and business pioneers). The Dyslexic Advantage provides the first complete portrait of dyslexia.
The Déjà Vu Enigma: A Journey Through the Anomalies of Mind, Memory, and Time
by Marie D. Jones Larry FlaxmanA deep dive into one of the most widely reported mysteries of the mind—both the scientific and paranormal theories—from the authors of The Grid.You feel like you’ve done something before . . . even as you do it for the very first time.You engage in a conversation and suddenly realize you’ve spoken those same words before . . . to the very same person. Yet you’re positive it’s the first time you’ve ever met.Déjà vu is the eerie sensation of “remembering” an experience or situation that never occurred. Scientific research into déjà vu has revealed intriguing theories, ranging from short-term memory misfires to neurophysiological disorders. Yet other theories suggest more paranormal causes for déjà vu, such as glimpses into parallel realities. Perhaps the true explanation lies somewhere in between.But déjà vu is only one of the many mysteries of the mind. The Déjà Vu Enigma also explores:Memory lapses, missing time, and fugue statesThe brain as both receiver and transmitter of realityAltered states of perception and consciousness, from hallucinations to religious visionsContagious thought, curses, demonic possession, and mass hysteriaDream states, lucid dreaming, and precognitive dreamsThe Grid and parallel universes as travel routes for mind trips, brain flips, and time slipsCome journey through a world as vast and uncharted as the Cosmos. A journey through the Inner Universe—the human mind.“From the dynamic team of Marie D. Jones & Larry Flaxman who have brought us some many wonderful books on fringe subject matter . . . a completely thought-provoking study.” —HorrorNews.net
The Déjà Vu Experience (Essays in Cognitive Psychology)
by Alan S. Brown Anne M. ClearyThe Déjà vu Experience, Second Edition covers the latest scientific discoveries regarding the strange sense of familiarity most of us have felt at one time or another when doing something for the first time. The book sheds light on this mysterious phenomenon, considering the latest neurophysiological investigations and research on possible reasons why déjà vu is often associated with a sense of predicting the future or knowing what happens next. In addition to summarizing the major historical and contemporary theoretical approaches to the déjà vu experience, this book aspires to stimulate additional research on this curious subjective phenomenon. Drawing on research from a range of fields including psychology, philosophy, and religion, it aims to demystify some of the more unsettling, spooky-seeming aspects of the déjà vu experience, elucidating possible mechanisms and underlying reasons for its occurrence. This edition has been thoroughly updated throughout to include over 200 new professional articles and book chapters related to déjà vu that have been published in the 18 years since the original book. By placing the scientific study of déjà vu within its historical context and covering a broad range of perspectives on the subject, this title will be invaluable to upper-level undergraduates, postgraduates, and researchers of Cognitive Psychology, specifically those focusing on Memory Phenomena.
The ECPH Encyclopedia of Mining and Metallurgy
by Xu KuangdiThis encyclopedia volume comprehensively reflects the basic knowledge and latest research results in the field of mining and metallurgy technology, as well as the latest characteristics of the development in this field. In this reference book, the knowledge system, basic concepts, basic theories, as well as important figures, representative works and institutions of these two engineering categories are well organized in encyclopedic entries. Among them, the content on mining engineering mainly includes mining and mineral processing theory, mining and mineral processing methods, as well as the safety and environmental knowledge involved in mining and mineral processing. In the metallurgical engineering field, it mainly covers metallurgy and metallurgy industry, ferrous metallurgy, non-ferrous metallurgy, powder metallurgy, plastic working of metal, coking chemicals, refractories, energy for metallurgy, physical chemistry of metallurgical process, etc.This is thefirst volume of a series of encyclopedias co-published by Encyclopedia of China Publishing House (ECPH), Beijing and Springer Nature.
The EIS Book: Managing and Preparing Environmental Impact Statements
by Charles H. EcclestonPoor Environmental Impact Statement (EIS) practice leads to poorly planned projects, and ultimately poor environmental protection. Written by recognized NEPA authority Charles H. Eccleston, The EIS Book: Managing and Preparing Environmental Impact Statements supplies focused direction on preparing an EIS, highlighting best professional practices (B
The ESC Textbook of Cardiovascular Imaging
by Jeroen J. Bax Frank E. Rademakers Jose Luis Zamorano Juhani Knuuti"The ESC Textbook of Cardiovascular Imaging" is a comprehensive guide to all forms of cardiovascular imaging. A disease based approach is followed and the book is comprised of 8 sections. Section 1 describes the imaging techniques available and Sections 2-8 describe the imaging modalities used to visualise cardiovascular diseases in seven main areas. Each section is subdivided into 2-7 chapters. The book is edited by four European opinion leaders in the fields of echocardiography, nuclear, CMR and CT imaging and has over 50 contributors, mainly from Europe. The printed version is complemented by a basic online version, accessible by means of a password, distributed with the book. The online version allows users to: download chapters for ease of use; provide links from all references to PubMed; allow searching of the text; and download figures and images for non-commercial use in PowerPoint presentations.
The ESCRT Complexes: Methods and Protocols (Methods in Molecular Biology #1998)
by Emmanuel Culetto Renaud LegouisThis detailed collection gathers both established and recent technical procedures to study the Endosomal Sorting Complex Required for Transport (ESCRT) complexes in a wide range of biological systems: Archaea, A. thaliana, U. maydis, S. cerevisiae, S. pombe, C. elegans, D. melanogaster, and mammalian cells. Opening with a section on imaging techniques, the book continues with chapters covering biochemical approaches presenting strategies for production and characterization of recombinant ESCRT proteins, or of specific ESCRT protein domains, as well as genetic and proteomic experimental approaches. Written for the highly successful Methods in Molecular Biology series, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, The ESCRT Complexes: Methods and Protocols serves as a compact guide for researchers interested in establishing an integrated approach to investigate the ESCRT machinery functions in cell biology.