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The Extended Phenotype: The Long Reach of the Gene
by Richard DawkinsIn this influential and controversial book that has become a classic in popular science writing, Dawkins furthers his fascinating look at the evolution of life and natural selection.
The Extended Specimen: Emerging Frontiers in Collections-Based Ornithological Research (Studies in Avian Biology)
by Michael WebsterThe Extended Specimen highlights the research potential for ornithological specimens, and is meant to encourage ornithologists poised to initiate a renaissance in collections-based ornithological research. Contributors illustrate how collections and specimens are used in novel ways by adopting emerging new technologies and analytical techniques. Case studies use museum specimens and emerging and non-traditional types of specimens, which are developing new methods for making biological collections more accessible and "usable" for ornithological researchers. Published in collaboration with and on behalf of The American Ornithological Society, this volume in the highly-regarded Studies in Avian Biology series documents the power of ornithological collections to address key research questions of global importance.
The Extinct Alphabet Book (Jerry Pallotta's Alphabet Books)
by Jerry PallottaLearn about the five-eyed Opabinia and the Four-toed Horse. Speculate about the life of the Jamaican Long-tongued Bat. Discover the fate of the beautiful Quagga. But don't look for any dinosaurs in this book. There aren't any!Millions of creatures other than dinosaurs are now extinct. In true alphabet book tradition, the author has found twenty-six of the most extraordinary past-inhabitants of the Earth.Jerry Pallotta and Ralph Masiello team up to provide exciting, accurate text and illustrations filled with unusual and amusing insight that will satisfy fans of all ages.
The Extracellular Matrix and the Tumor Microenvironment (Biology of Extracellular Matrix #11)
by Ilona Kovalszky Marco Franchi Laura D. AlanizThis book introduces the most important and best studied extracellular and pericellular molecules of the tumor microenvironment. It gives a comprehensive overview of their role in tumor development and cancer progression.Twelve chapters deal with the biochemical and biophysical background of extracellular matrix (ECM) changes in the tumor stroma compared to the physiological state. The reader learns about the major ECM components that are deregulated during cancer development and how they are associated with cancer progression associated with survival, inflammation process, among others. These are followed by recent data about the cooperative activity of extracellular matrix in tumor metabolism, promoting cancer progression.Two chapters focus specifically on the critical role of the ECM in tumor angiogenesis, linking this process to cellular infiltration and metastatic behavior of tumors. The final part describes how the ECM influences the success of immuno- and chemotherapy in cancer patients, its potential as biomarkers for diagnosis, prognosis, and therapeutic target, as well as the mechanism of resistance-associated changes in the ECM. This book is an interesting read for anyone who want to know more about ECM and cancer biology. Early career scientists can use it as an introduction to the field, offering an excellent tool for studying ECM. Advanced researchers and clinicians can gain a broader overview of the subject, considering the role of ECM for influencing every cancer hallmark as well as in the response of cancer treatments. The work serves to inspire future research and shows that the ECM should be considered as an important factor in the development of cancer therapeutics. The series "Biology of Extracellular Matrix" is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
The Extracellular Matrix in Genetic Skeletal Disorders (Biology of Extracellular Matrix #16)
by Antonio Rossi Frank ZauckeThis book explores how defects in extracellular matrix (ECM) proteins, their post-translational modifications, and intracellular trafficking impact cartilage and bone integrity. It underscores the ECM's role in providing structural support, establishing morphogenetic gradients, and interacting with cell surface receptors in musculoskeletal tissues. The book delves into the structure and biology of the ECM in the skeleton, discussing skeletal disorders caused by mutations in genes associated with ECM proteins, synthesis, turnover, and signal transduction. Authored by experts who have made significant discoveries in the molecular mechanisms of skeletal disorders and are developing therapeutic strategies, this book is an invaluable research for both scientists and clinicians seeking a comprehensive understanding of this growing and exciting field. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
The Extracellular Matrix: an Overview
by Robert MechamKnowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series "Biology of Extracellular Matrix" provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.
The Extraordinary Biology of the Naked Mole-Rat (Advances in Experimental Medicine and Biology #1319)
by Rochelle Buffenstein Thomas J. Park Melissa M. HolmesThis volume focuses on the huge advances in the last 25 years on the use of this animal model for biomedical research (cancer, heart disease and neurodegeneration), fundamental neuroscience and basic subterranean biology. In 2013, Science magazine named the naked mole-rat as the Vertebrate of the Year. This was partly due to research carried out documenting its extreme longevity, negligible senescence, and prolonged maintenance of cancer free, good health well into old age as well as seminal work on mechanisms involved in these processes, pain and hypoxia resistance. In addition to this research focus on longevity and chronic diseases such as cancer and cardiovascular disease, the naked mole-rat has also made a substantial contribution to the fields of ecophysiology, neuroscience and behavior. With international contributions, this book provides a valuable text for zoological students, behavioral scientists and biomedical researchers.
The Extraordinary Chemistry of Ordinary Things
by Carl H. SnyderShows how chemistry affects our lives. * To emphasize the experimental basis of chemistry, chapters begin with demonstrations that readers can perform for themselves. * Think, Speculate, Reflect, and Ponder sections include questions that ask readers to think critically about the connections between chemistry, society, and individual values.
The Extraordinary World of Birds (The Magic and Mystery of the Natural World)
by David LindoEnter the world of birds for an incredible journey through the skies, into trees, and even underground.Parrots, hummingbirds, eagles, and more swoop across the pages of this colorful bird book, which combines gorgeous illustrations and photos to help young enthusiasts learn all about the wonderful world of birds. From frozen icescapes to sweltering deserts, from prehistoric ancestors to amazing adaptations, they&’ll discover the surprising homes and habits of our feathered friends. They&’ll also find out about how we can help protect birds and their natural habitats.The Extraordinary World of Birds, illustrated by Claire McElfatrick, takes children on a fascinating journey, showing them just how amazing birds are, what they do for our planet, and how we can help them. It includes bird families such as gamebirds, flightless birds, and perching birds, plus amazing facts on how birds talk to each other, what they eat, how they find partners, and how they are able to fly.
The Extraordinary eTab of Julian Newcomber
by Michael SeeseJoin Julian Newcomber on an extraordinary time travel adventure with The Extraordinary eTab of Julian Newcomber. When Julian's inventor father introduces him to his latest invention, a tablet that allows the user to travel through time, his world is turned upside down. As Julian and his family navigate the challenges of their new home, Julian also has a big problem to solve for his Future Self.This middle grade novel combines elements of science fiction, family dynamics, and the excitement of time travel, making it a must-read for young readers who love a good adventure. Get ready to be transported through time and space with Julian and his extraordinary eTab!
The Extraterrestrial Life Debate, 1750-1900
by Michael J. Crowe"There isn't an uninteresting page in it. It is a masterly review of an intriguing subject, erudite and entertaining, clear and all-encompassing reading for anyone interested in 'one of the most wondrous and noble questions in nature' - does extraterrestrial life exist?" - New Scientist.Are we alone in the universe? Are there other beings on other worlds who gaze into the night sky and try to imagine us, as we try to imagine them? Those questions have been debated since antiquity, but it was during the Enlightenment that they particularly began to engage the interest of prominent scientists and thinkers. In this fascinating volume, Professor Michael Crowe offers the first in-depth study in English of the international debate that developed between 1750 and 1900 concerning the existence of extraterrestrial life, a problem that engaged an extraordinary variety of Western thinkers across the spectrum of intellectual endeavor. Astronomers such as Herschel, Bode, Lalande, and Flammarion all weighed in, along with French philosophers Rousseau and Voltaire, American patriot Thomas Paine, Scots churchman Thomas Chalmers, and a host of others. Professor Crowe gives them all their say, as they address the question as a point of science, as a problem of philosophy, as well as a religious issue. The book ends with the "discovery" by Schiaparelli of the canals of Mars, the expansion of the canal theory by the American astronomer Percival Lowell, and the culmination of the canal controversy with the demonstration of its illusory nature."Crowe's book is lucid and rich in historical detail. His analysis is so fascinating and his comments on the contemporary debate so pertinent that The Extraterrestrial Life Debate can be recommended for the thoughtful reader without reservation. While a model of scholarly analysis, it has the unusual virtue of reading with the excitement of high adventure." - Sky & Telescope.
The Extravagant Universe: Exploding Stars, Dark Energy, and the Accelerating Cosmos
by Robert P. KirshnerThe Extravagant Universe tells the story of a remarkable adventure of scientific discovery. One of the world's leading astronomers, Robert Kirshner, takes readers inside a lively research team on the quest that led them to an extraordinary cosmological discovery: the expansion of the universe is accelerating under the influence of a dark energy that makes space itself expand. In addition to sharing the story of this exciting discovery, Kirshner also brings the science up-to-date in a new epilogue. He explains how the idea of an accelerating universe--once a daring interpretation of sketchy data--is now the standard assumption in cosmology today. This measurement of dark energy--a quality of space itself that causes cosmic acceleration--points to a gaping hole in our understanding of fundamental physics. In 1917, Einstein proposed the "cosmological constant" to explain a static universe. When observations proved that the universe was expanding, he cast this early form of dark energy aside. But recent observations described first-hand in this book show that the cosmological constant--or something just like it--dominates the universe's mass and energy budget and determines its fate and shape. Warned by Einstein's blunder, and contradicted by the initial results of a competing research team, Kirshner and his colleagues were reluctant to accept their own result. But, convinced by evidence built on their hard-earned understanding of exploding stars, they announced their conclusion that the universe is accelerating in February 1998. Other lines of inquiry and parallel supernova research now support a new synthesis of a cosmos dominated by dark energy but also containing several forms of dark matter. We live in an extravagant universe with a surprising number of essential ingredients: the real universe we measure is not the simplest one we could imagine.
The Extreme Future
by James CantonA renowned global futurist prepares businesses and individuals for the radical changes on the horizon An advisor to three presidents spanning over thirty years, Dr. James Canton identifies probable outcomes and future trends in business, technology, environment, terrorism, population, and medicine to help companies and individuals prepare for the coming complex and volatile global changes, including: * How climate change and energy trends will reshape the planet* How astounding medicine trends will enhance people's lives* How the rise of China will bring on a new global power struggle In the tradition of Future Shock, Megatrends, and The Tipping Point, Extreme Future is the essential forecasting handbook for navigating the twenty-first century.
The Extreme Life of the Sea
by Anthony R. Palumbi Stephen R. PalumbiA thrilling tour of the sea's most extreme species, written by one of the world's leading marine scientistsThe ocean teems with life that thrives under difficult situations in unusual environments. The Extreme Life of the Sea takes readers to the absolute limits of the ocean world—the fastest and deepest, the hottest and oldest creatures of the oceans. It dives into the icy Arctic and boiling hydrothermal vents—and exposes the eternal darkness of the deepest undersea trenches—to show how marine life thrives against the odds. This thrilling book brings to life the sea's most extreme species, and tells their stories as characters in the drama of the oceans. Coauthored by Stephen Palumbi, one of today’s leading marine scientists, The Extreme Life of the Sea tells the unforgettable tales of some of the most marvelous life forms on Earth, and the challenges they overcome to survive. Modern science and a fluid narrative style give every reader a deep look at the lives of these species.The Extreme Life of the Sea shows you the world’s oldest living species. It describes how flying fish strain to escape their predators, how predatory deep-sea fish use red searchlights only they can see to find and attack food, and how, at the end of her life, a mother octopus dedicates herself to raising her batch of young. This wide-ranging and highly accessible book also shows how ocean adaptations can inspire innovative commercial products—such as fan blades modeled on the flippers of humpback whales—and how future extremes created by human changes to the oceans might push some of these amazing species over the edge.An enhanced edition is also available and includes eleven videos.
The Extreme Life of the Sea (Princeton Science Library #125)
by Anthony R. Palumbi Stephen R. PalumbiA thrilling tour of the sea's most extreme species, coauthored by one of the world's leading marine scientistsThe ocean teems with life that thrives under difficult situations in unusual environments. The Extreme Life of the Sea takes readers to the absolute limits of the ocean world—the fastest and deepest, the hottest and oldest creatures of the oceans. It dives into the icy Arctic and boiling hydrothermal vents—and exposes the eternal darkness of the deepest undersea trenches—to show how marine life thrives against the odds. This thrilling book brings to life the sea's most extreme species, and tells their stories as characters in the drama of the oceans. Coauthored by Stephen Palumbi, one of today’s leading marine scientists, The Extreme Life of the Sea tells the unforgettable tales of some of the most marvelous life forms on Earth, and the challenges they overcome to survive. Modern science and a fluid narrative style give every reader a deep look at the lives of these species.The Extreme Life of the Sea shows you the world’s oldest living species. It describes how flying fish strain to escape their predators, how predatory deep-sea fish use red searchlights only they can see to find and attack food, and how, at the end of her life, a mother octopus dedicates herself to raising her batch of young. This wide-ranging and highly accessible book also shows how ocean adaptations can inspire innovative commercial products—such as fan blades modeled on the flippers of humpback whales—and how future extremes created by human changes to the oceans might push some of these amazing species over the edge.
The Eye of War: Military Perception from the Telescope to the Drone
by Antoine BousquetHow perceptual technologies have shaped the history of war from the Renaissance to the present From ubiquitous surveillance to drone strikes that put &“warheads onto foreheads,&” we live in a world of globalized, individualized targeting. The perils are great. In The Eye of War, Antoine Bousquet provides both a sweeping historical overview of military perception technologies and a disquieting lens on a world that is, increasingly, one in which anything or anyone that can be perceived can be destroyed—in which to see is to destroy. Arguing that modern-day global targeting is dissolving the conventionally bounded spaces of armed conflict, Bousquet shows that over several centuries, a logistical order of militarized perception has come into ascendancy, bringing perception and annihilation into ever-closer alignment. The efforts deployed to evade this deadly visibility have correspondingly intensified, yielding practices of radical concealment that presage a wholesale disappearance of the customary space of the battlefield. Beginning with the Renaissance&’s fateful discovery of linear perspective, The Eye of War discloses the entanglement of the sciences and techniques of perception, representation, and localization in the modern era amid the perpetual quest for military superiority. In a survey that ranges from the telescope, aerial photograph, and gridded map to radar, digital imaging, and the geographic information system, Bousquet shows how successive technological systems have profoundly shaped the history of warfare and the experience of soldiering. A work of grand historical sweep and remarkable analytical power, The Eye of War explores the implications of militarized perception for the character of war in the twenty-first century and the place of human subjects within its increasingly technical armature.
The Eye of the Sandpiper: Stories from the Living World
by Brandon KeimIn The Eye of the Sandpiper, Brandon Keim pairs cutting-edge science with a deep love of nature, conveying his insights in prose that is both accessible and beautiful. In an elegant, thoughtful tour of nature in the twenty-first century, Keim continues in the tradition of Lewis Thomas, Stephen Jay Gould, and David Quammen, reporting from the frontiers of science while celebrating the natural world’s wonders and posing new questions about our relationship to the rest of life on Earth. The stories in The Eye of the Sandpiper are arranged in four thematic sections. Each addresses nature through a different lens. The first is evolutionary and ecological dynamics, from how patterns form on butterfly wings to the ecological importance of oft-reviled lampreys. The second section explores the inner lives of animals, which science has only recently embraced: empathy in rats, emotions in honeybees, spirituality in chimpanzees. The third section contains stories of people acting on insights both ecological and ethological: nourishing blighted rivers, but also caring for injured pigeons at a hospital for wild birds and demanding legal rights for primates. The fourth section unites ecology and ethology in discussions of ethics: how we should think about and behave toward nature, and the place of wildness in a world in which space for wilderness is shrinking. By appreciating the nonhuman world more fully, Keim writes, "I hope people will also act in ways that nourish rather than impoverish its life—which is, ultimately, the problem that needs to be solved at this Anthropocene moment, with a sixth mass extinction looming, once-common animals becoming rare, and Earth straining to support 7.5 billion people. The solution will come from a love of nature rather than chastisement or lamentation."
The Eye of the Whale: A Rescue Story (Tilbury House Nature Book #0)
by Jennifer O'ConnellOn a cool December morning near San Francisco, a distress call was radioed to shore by a local fisherman. He had discovered a humpback whale tangled in hundreds of yards of crab-trap lines, struggling to stay afloat. A team of volunteers answered the call, and four divers risked their lives to rescue the enormous animal. It was the first successful whale disentanglement performed off the West Coast of the United States and prompted a rare and remarkable demonstration of animal behavior. As people found out about the event, questions arose. Did the whale help the divers by staying still and calm as they cut the lines or was she just exhausted? Was the whale full of joy after being freed or did she swim in circles to stretch out her huge body after being tied up for so long? How do we explain the whale nudging all the divers, then looking directly at them? (The divers said that this was one of the most fantastic moments of their lives.) This celebrated story, beautifully depicted in Jennifer O'Connell's mesmerizing paintings, will make you wonder about animal emotions and the unique connections we can have with other animals, even whales. To research The Eye of the Whale, Jennifer traveled to San Francisco where she met Captain Mick Menigoz and rode his rescue boat, Superfish, out into the Pacific Ocean to the area where the events in the book took place. This experience fueled her inspiration as she created the images and words of this extraordinary story.
The Eyeball Alphabet Book (Jerry Pallotta's Alphabet Books)
by Jerry PallottaBest-selling author Jerry Pallotta takes a peek at eyes from across the animal kingdom in this hilarious and fact-packed alphabet book.The eyes have it! Laugh as you learn by staring right into the eyes of familiar animals (A is for alligator eye) and not-so-familiar ones (Z is for zebu eye!). Readers of all ages will be entertained with every page turn. Language learning bonus: each page defines an idiom that includes the word "eye"!
The FLP Microsatellite Platform
by Jens EickhoffThis book represents the Flight Operations Manual for a reusable microsatellite platform - the "Future Low-cost Platform" (FLP), developed at the University of Stuttgart, Germany. It provides a basic insight on the onboard software functions, the core data handling system and on the power, communications, attitude control and thermal subsystem of the platform. Onboard failure detection, isolation and recovery functions are treated in detail. The platform is suited for satellites in the 50-150 kg class and is baseline of the microsatellite "Flying Laptop" from the University. The book covers the essential information for ground operators to controls an FLP-based satellite applying international command and control standards (CCSDS and ECSS PUS). Furthermore it provides an overview on the Flight Control Center in Stuttgart and on the link to the German Space Agency DLR Ground Station which is used for early mission phases. Flight procedure and mission planning chapters complement the book.
The FOS and JUN Families of Transcription Factors (CRC Press Revivals)
by Peter E. Angel Peter HerrlichThis book introduces and analyzes the crucial role of AP-1 in cell growth, proliferation, differentiation, and apoptosis. AP-1 is the endpoint of several pathways of signal transduction, including one that triggers cancerous growth. The control of its activity is an issue of basic science, cancer therapy, and other diseases. The chapters provide multiple viewpoints of the emerging data on AP-1, including its role as a factor regulating genes involved in the metastatic properties of cancer, as a factor that interacts with viral gene products, and as a part of the mechanism by which steroid and retinoic acid receptors function as anti-inflammatory proteins.
The Fabric of Empire: Material and Literary Cultures of the Global Atlantic, 1650-1850 (Studies in Early American Economy and Society from the Library Company of Philadelphia)
by Danielle C. SkeehanRevealing the entangled lives of texts and textiles in the early modern Atlantic world."Textiles are the books that the colony was not able to burn."—Asociación Femenina para el Desarrollo de Sacatepéquez (AFEDES)A history of the book in the Americas, across deep time, would reveal the origins of a literary tradition woven rather than written. It is in what Danielle Skeehan calls material texts that a people's history and culture is preserved, in their embroidery, their needlework, and their woven cloth. In defining textiles as a form of cultural writing, The Fabric of Empire challenges long-held ideas about authorship, textuality, and the making of books. It is impossible to separate text from textiles in the early modern Atlantic: novels, newspapers, broadsides, and pamphlets were printed on paper made from household rags. Yet the untethering of text from textile served a colonial agenda to define authorship as reflected in ink and paper and the pen as an instrument wielded by learned men and women. Skeehan explains that the colonial definition of the book, and what constituted writing and authorship, left colonial regimes blind to nonalphabetic forms of media that preserved cultural knowledge, history, and lived experience. This book shifts how we look at cultural objects such as books and fabric and provides a material and literary history of resistance among the globally dispossessed.Each chapter examines the manufacture and global circulation of a particular type of cloth alongside the complex print networks that ensured the circulation of these textiles, promoted their production, petitioned for or served to curtail the rights of textile workers, facilitated the exchange of textiles for human lives, and were, in turn, printed and written on surfaces manufactured from broken-down linen and cotton fibers. Bringing together methods and materials traditionally belonging to literary studies, book history, and material culture studies, The Fabric of Empire provides a new model for thinking about the different media, languages, literacies, and textualities in the early Atlantic world.
The Fabric of Reality
by David DeutschAn extraordinary and challenging synthesis of ideas uniting Quantum Theory, and the theories of Computation, Knowledge and Evolution, Deutsch's extraordinary book explores the deep connections between these strands which reveal the fabric of realityin which human actions and ideas play essential roles.
The Fabric of Space: Water, Modernity, and the Urban Imagination (The\mit Press Ser.)
by Matthew GandyA study of water at the intersection of landscape and infrastructure in Paris, Berlin, Lagos, Mumbai, Los Angeles, and London.Water lies at the intersection of landscape and infrastructure, crossing between visible and invisible domains of urban space, in the tanks and buckets of the global South and the vast subterranean technological networks of the global North. In this book, Matthew Gandy considers the cultural and material significance of water through the experiences of six cities: Paris, Berlin, Lagos, Mumbai, Los Angeles, and London. Tracing the evolving relationships among modernity, nature, and the urban imagination, from different vantage points and through different periods, Gandy uses water as a lens through which to observe both the ambiguities and the limits of nature as conventionally understood. Gandy begins with the Parisian sewers of the nineteenth century, captured in the photographs of Nadar, and the reconstruction of subterranean Paris. He moves on to Weimar-era Berlin and its protection of public access to lakes for swimming, the culmination of efforts to reconnect the city with nature. He considers the threat of malaria in Lagos, where changing geopolitical circumstances led to large-scale swamp drainage in the 1940s. He shows how the dysfunctional water infrastructure of Mumbai offers a vivid expression of persistent social inequality in a postcolonial city. He explores the incongruous concrete landscapes of the Los Angeles River. Finally, Gandy uses the fictional scenario of a partially submerged London as the starting point for an investigation of the actual hydrological threats facing that city.
The Fabric of the Cosmos: Space, Time, and the Texture of Reality (Penguin Press Science Ser.)
by Brian GreeneFrom Brian Greene, one of the world's leading physicists and author the Pulitzer Prize finalist The Elegant Universe, comes a grand tour of the universe that makes us look at reality in a completely different way.Space and time form the very fabric of the cosmos. Yet they remain among the most mysterious of concepts. Is space an entity? Why does time have a direction? Could the universe exist without space and time? Can we travel to the past? Greene has set himself a daunting task: to explain non-intuitive, mathematical concepts like String Theory, the Heisenberg Uncertainty Principle, and Inflationary Cosmology with analogies drawn from common experience. From Newton's unchanging realm in which space and time are absolute, to Einstein's fluid conception of spacetime, to quantum mechanics' entangled arena where vastly distant objects can instantaneously coordinate their behavior, Greene takes us all, regardless of our scientific backgrounds, on an irresistible and revelatory journey to the new layers of reality that modern physics has discovered lying just beneath the surface of our everyday world.From the Trade Paperback edition.