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The Laboratory Guinea Pig
by Donna J. Clemons Jennifer L. SeemanLaboratory animals play an important role in biomedical research and advances. Expanded, updated, and now published in full color to provide greater clarity to the techniques and concepts discussed, this guide presents basic information and common procedures in detail to provide a quick reference for investigators, technicians, and caretakers in the laboratory setting. It includes additional information on the research uses of the guinea pig along with updated medical care information.
The Laboratory Hamster and Gerbil (Laboratory Animal Pocket Reference)
by Karl J. Field Amber L. SiboldThe Laboratory Hamster and Gerbil details basic information and common procedures for individuals performing research with hamsters and gerbils. It includes duties of animal facility management, animal husbandry, regulatory compliance, and technical procedures and assists in the humane care and use of hamsters and gerbils in the laboratory. It prov
The Laboratory Mouse (Laboratory Animal Pocket Reference)
by Mark A. Suckow Sara Hashway Kathleen R. Pritchett-CorningWith the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. Revised to reflect advances since the second edition, The Laboratory Mouse continues to be the most accessible reference on the biology and care of the mouse in research settings. This guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers on the humane care and use of the mouse. The new edition adds information on novel technologies such as CRISPR-Cas and on housing systems and management practices; it covers new concepts such as pain assessment by facial expression and the importance of nest-building as an assessment tool of well-being. There are now expanded sections on anesthesia and analgesia, and on behavior and enrichment. An ideal quick reference for investigators, technicians, and animal caretakers charged with the care and/or use of mice in a research setting, this book will be particularly valuable to those new to working with mice who need to start research programs using these animals.
The Laboratory Mouse: A Guide to the Location and Orientation of Tissues for Optimal Histological Evaluation
by Susan Ryan Jennifer Johnson Brian DelGiudice Dinesh Bangari Eleanor Peterson Gregory Ulinski Beth ThurbergKey features: High quality full color photographs and descriptive texts on the location and removal of the organs from the mouse Instructive methods and clear visuals for trimming and orienting the organs for paraffin histology to obtain the best possible sections for analysis Full color photomicrographs of the resulting section for each organ stained with hematoxylin and eosin demonstrating important features and landmarks for the histologist to ensure the optimal area for analysis is achieved All in one, easy to use guide organized by individual organs of the laboratory mouse Spiralbound for easy reference in the lab This "one-stop" guide offers an essential resource for any academic, research or development operation where mouse necropsy and/or histology are performed. Connecting the reader ‘from the mouse to the microscope’, it provides a detailed guide for locating, trimming, orientating and embedding of the most frequently investigated tissues collected in the laboratory mouse. It shows where the organs reside in the mouse, how to trim and embed them as well as the resulting optimal sections. This guide brings together the wealth of scattered information into one high-quality text, the emphasis is on providing knowledge that will help histologists and scientists get better results in any downstream assays where ideal sections are needed.
The Laboratory Nonhuman Primate (Laboratory Animal Pocket Reference)
by Jeffrey D. Fortman Terry A. Hewett Lisa C. HallidayKey features Contains 28 updated tables designed as quick, easy-to-use references for New and Old World species Provides over 100 photographs and illustrations, most now in color, depicting aspects of nonhuman primate biology, behavior, management practices, diseases, and technical procedures Gives a concise overview of regulatory considerations for the use of nonhuman primates in biomedical research Expands the Veterinary Care chapter to include new sections on nutritional support, behavioral conditions, dental care, and updated information on anesthetic and analgesic drugs Presents step-by-step descriptions of common and advanced sampling techniques Includes extensive resource lists for vendors of animals, feed, sanitation supplies, caging, anesthetic equipment, and veterinary and research supplies Extensively updated to include current literature, The Laboratory Nonhuman Primate, Second Edition, continues to serve as a quick reference source for technicians, caretakers, veterinarians, researchers, and students working with primates in biomedical research. It provides details on basic husbandry and covers biologic characteristics, regulatory compliance, common diseases, and anesthetic management.The text gives easy-to-follow descriptions of basic technical procedures including restraint, intubation, tuberculin skin testing, and collection of blood and urine samples. It also reviews advanced sampling procedures including collection of bone marrow, cerebrospinal fluid, bronchoalveolar lavage fluid, and rectal mucosal biopsy. The Laboratory Nonhuman Primate presents information in a clear, concise format to allow readers to incorporate concepts and techniques into the standard operating procedures of a facility.
The Laboratory Pig (Laboratory Animal Pocket Reference)
by Kirsten Rosenmay Jacobsen Aage K Olsen Alstrup Axel K. Hansen Peter BollenSince the popular second edition of The Laboratory Swine was published more than a decade ago, the number of pigs used in toxicity studies has increased as an alternative to commonly used non-rodent species, while, at the same time, large developments have been made in welfare concepts of laboratory animals. Pigs have gained prominence in both basic and applied research, leading to a significant increase in publication activity.This third edition summarizes these new insights, raising the bar for humane care and use of pigs, from agricultural sources to genetically and microbiological defined minipigs. Aimed at animal caretakers, technicians, laboratory animal veterinarians, and investigators planning and performing studies on pigs, it provides an overview with extensive references for further study. The book has been updated with a special focus on refined methods for housing and handling pigs, including an updated description of commonly performed experimental and surgical procedures.Continuing its legacy as the premier reference on the care and use of pigs in the laboratory, the small, practical, and accessible format makes this an easy "go-to" book, with easy-to-find information and high-quality color images. The third edition aims to contribute to humane use and care for laboratory pigs in all aspects of housing, husbandry, veterinary care, and experimental techniques.
The Laboratory Rabbit (Laboratory Animal Pocket Reference)
by Mark A. Suckow Valerie Schroeder Fred A. DouglasWith laboratory animals, especially rabbits, playing such an important role in biomedical research, the humane care of these animals is an ongoing concern. The Laboratory Rabbit, Second Edition presents basic information and common procedures in detail to provide a quick reference for caretakers, technicians, and researchers in a laboratory setting
The Laboratory Rat (Laboratory Animal Pocket Reference)
by Patrick Sharp Jason S. VillanoRats have long been recognized as a valuable biomedical research model, notably in the investigation of aging, toxicology, addiction, and common human diseases such as diabetes and hypertension. In many instances, individuals conducting such research studies are charged with important responsibilities, including animal facility management, animal h
The Laboratory Small Ruminant (Laboratory Animal Pocket Reference)
by Matthew J. Allen Gary L. BorkowskiThe Laboratory Small Ruminant details basic information and common procedures for individuals performing research with small ruminants. Details include duties of animal husbandry, regulatory compliance, and technical procedures. It is designed to assist in the humane care and use of small ruminants in the laboratory and to provide immediate informa
The Laboratory Swine (Laboratory Animal Pocket Reference)
by Peter J. Bollen Axel K. Hansen Aage K Olsen AlstrupAddressing the biology, husbandry, management, veterinary care and research applications of both large and miniature swine, this color resource is renowned as the laboratory reference on swine. It is thoroughly updated and includes a major revision to the anesthetics section. It also places a heightened focus on animal welfare and addresses important considerations related to genetically modified swine. The Laboratory Swine, Second Edition is ideal for animal caretakers, technicians, investigators, and laboratory animal veterinarians as a single-source reference that contributes to the humane care and use of swine in research.
The Laboratory Xenopus sp. (Laboratory Animal Pocket Reference)
by Sherril L. GreenXenopus have gained increasing popularity as a laboratory animal and continue to serve as an important part of biomedical research. This book offers a practical reference to the care and maintenance of captive clawed frogs. With full-color illustrations of management practices and technical procedures, the text explores the wide range of responsibilities facing individuals who work with this species, from husbandry, compliance, and veterinary care to housing and water quality management. Numerous figures and tables enhance understanding of concepts. An experienced researcher at a top tier institution, the author provides an invaluable guide for facility technicians and animal caretakers.
The Laboratory Zebrafish (Laboratory Animal Pocket Reference)
by Carole Wilson David ChuThis guide covers all aspects pertaining to the use of zebrafish including their basic biology, humane care and management, husbandry, life support systems, regulatory compliance, technical procedures, veterinary care, and water quality management. The zebrafish is now a mainstream model animal employed by scientists to study everything from stem cells to the basis of behavioral changes induced by drug addiction. However, there are few accepted and established standards for husbandry, management, and care for the fish in laboratory settings and even fewer comprehensive and constantly reliable resources. To this end, the goal of this handbook is to provide managers, veterinarians, investigators, technicians, and regulatory personnel with a concise yet thorough reference on zebrafish biology, care, husbandry, and management. The new edition includes more figures, tables and bullet points, a wealth of new full-color images, major updates on health and welfare (including colony health surveillance and viruses), and a complete overhaul of the compliance section to address more international concerns.
The Laboratory Zebrafish (Laboratory Animal Pocket Reference)
by Claudia Harper Christian LawrenceLike other books in the Laboratory Animal Pocket Reference Series, this guide covers all aspects pertaining to the use of these organisms including their basic biology, humane care and management, husbandry, life support systems, regulatory compliance, technical procedures, veterinary care, and water quality management. In the relatively brief span
The Laboratory of the Mind: Thought Experiments in the Natural Sciences (Philosophical Issues In Science Ser.)
by James Robert BrownNewton's bucket, Einstein's elevator, Schrödinger's cat – these are some of the best-known examples of thought experiments in the natural sciences. But what function do these experiments perform? Are they really experiments at all? Can they help us gain a greater understanding of the natural world? How is it possible that we can learn new things just by thinking? In this revised and updated new edition of his classic text The Laboratory of the Mind, James Robert Brown continues to defend apriorism in the physical world. This edition features two new chapters, one on “counter thought experiments” and another on the development of inertial motion. With plenty of illustrations and updated coverage of the debate between Platonic rationalism and classic empiricism, this is a lively and engaging contribution to the field of philosophy of science.
The Labyrinth of Star Formation
by Dimitris Stamatellos Simon Goodwin Derek Ward-ThompsonThis volume contains the proceedings from the conference "The Labyrinth of Star Formation" that was held in Crete, Greece, in June 2012, to honour the contributions to the study of star formation made by Professor Anthony Whitworth of Cardiff University. The book covers many aspects of theoretical and observational star formation: low-mass star formation; young circumstellar discs; computational methods; triggered star formation; the stellar initial mass function; high-mass star formation and stellar clusters. Each section starts with a review paper, followed by papers discussing recent theoretical and observational work. This volume summarises our current understanding of star formation and is useful for both graduate students and researchers alike.
The Labyrinth of Technology
by Willem H. VanderburgWhy does modern technology succeed so brilliantly in some respects and simultaneously fail in others? While he was completing a doctoral thesis in mechanical engineering in the late 60s and early 70s, Willem Vanderburg became convinced that the environmental crisis and the possible limits to growth would require a fundamental change in the engineering, management and regulation of technology.In this volume he exposes the limitations of conventional approaches in these fields. Modern societies urgently need to rethink the intellectual division of labour in science and technology and the corresponding organization of the university, corporation, and government in order to get out of a self-destructive pattern where problems are first created by some than then dealt with by others, making it almost impossible to get to the roots of anything. The result is what he calls the labyrinth of technology, a growing patchwork of compensations that merely displace and transform problems from one place to another. The author's diagnosis suggests the remedy: a new, preventive strategy that situates technological and economic growth in its human, societal, and biospheric contexts, and calls for a synthesis of methods in engineering, management, and public policy, and of approaches in the social sciences and humanities. He also suggests that this same synthesis can be applied in medicine, law, social work, and other professions.The Labyrinth of Technology is a unique and invaluable text for students, academics and laypersons in all disciplines, and speaks to those who are torn between the benefits that modern technology provides and the difficulties it creates in our individual and collective lives.
The Lactoperoxidase System: Chemistry and Biological Significance
by Kenneth PruittThis book reviews the major biochemical and biological properties of the lactoperoxidase system including both the bovine milk and human salivary enzymes. It focuses on the basic chemistry of peroxidase-catalyzed reactions and clinical applications of peroxide system antimicrobial effects.
The Lagoon: Encounters with the Whales of San Ignacio
by James Michael DorseyA voyage to a magical marine haven, the San Ignacio Lagoon in Baja, Mexico, where the connection between man and beast is like no other on Earth. Once a killing ground for whalers hunting a leviathan they called the “devilfish,” the San Ignacio Lagoon in Baja, Mexico, is now an environmental and spiritual sanctuary—the only place in the world where animals in their natural aquatic environment routinely seek out human contact. A nursery for the gray whale since before recorded history, the lagoon and its stories, told here by resident naturalist James Michael Dorsey, illuminate the magic of human connection to animals, and what those bonds teach us about ourselves and our purpose on this shared planet. Weaving two decades of San Ignacio adventures in the company of his wife Irene with the fascinating history of the lagoon, Dorsey vividly captures the lively people of Baja, like the mystical godfather of whale-watching, Pachico Mayoral, as well as the whales he’s bonded with over the years, like Slackjaw, Patch, and Dervish—their individual personalities, their epic migration to and from the Pacific Northwest, and the science behind their behavior. Looming over his journeys are the many dangers to the area, from the Mitsubishi Corporation’s attempts to build salt works to plans for resort development on the Baja coast, to pollution and climate change, and even to the orcas who hunt the gray whales. The future of this refuge has never looked more threatened. A tale of wondrous bonds between the intelligent, spirited gray whales and the men, women, and children from around the world who come to this place to touch, kiss, and play with them—The Lagoon is a testament to the importance of preserving these animals and their natural habitats.
The Lagoon: How Aristotle Invented Science
by Armand Marie LeroiA brilliant study of Aristotle as biologist The philosophical classics of Aristotle loom large over the history of Western thought, but the subject he most loved was biology. He wrote vast volumes about animals. He described them, classified them, told us where and how they live and how they develop in the womb or in the egg. He founded a science. It can even be said that he founded science itself. In The Lagoon, acclaimed biologist Armand Marie Leroi recovers Aristotle&’s science. He revisits Aristotle&’s writings and the places where he worked. He goes to the eastern Aegean island of Lesbos to see the creatures that Aristotle saw, where he saw them. He explores Aristotle&’s observations, his deep ideas, his inspired guesses—and the things he got wildly wrong. He shows how Aristotle&’s science is deeply intertwined with his philosophical system and reveals that he was not only the first biologist, but also one of the greatest. The Lagoon is both a travelogue and a study of the origins of science. And it shows how a philosopher who lived almost two millennia ago still has so much to teach us today.
The Lake Charr Salvelinus namaycush: Biology, Ecology, Distribution, and Management (Fish & Fisheries Series #39)
by Andrew M. Muir Charles C. Krueger Michael J. Hansen Stephen C. RileyThe lake charr Salvelinus namaycush is a ubiquitous member of cold-water lake ecosystems in previously glaciated regions of northern continental U.S., Alaska, and Canada that often support important commercial, recreational, and subsistence fisheries. The lake charr differs from other charrs by its large size, longevity, iteroparity, top-predator specialization, reduced sexual dimorphism, prevalence of lacustrine spawning, and use of deepwater habitat. The species is remarkably variable in phenotype, physiology, and life history, some of which is reflected in its ecology and genetics, with as many as four morphs or ecotypes co-occurring in a single lake. The lake charr is often the top predator in these systems, but is highly adaptable trophically, and is frequently planktivorous in small lakes. The lake charr by their name highlights their common habitat, lakes both large and small, but often frequents rivers and occasionally moves into the Arctic Ocean. Movement and behaviour of lake charr are motivated by access to cool, well-oxygenated water, foraging opportunities, predator avoidance, and reproduction. Owing to their broad distribution and trophic level, the lake charr serves as a sentinel of anthropogenic change. This volume will provide an up-to-date summary of what is currently known about lake charr from distribution to genetics to physiology to ecology. The book provides a compilation and synthesis of available information on the lake charr, beginning with an updated distribution and a revised treatment of the paleoecology of the species. Understanding of ecological and genetic diversity and movement and behaviour of the species has advanced remarkably since the last major synthesis on the species over 40 years ago. Mid-sections of the book provide detailed accounts of the biology and life history of the species, and later sections are devoted to threats to conservation and fishery management practices used to ensure sustainability. A new standard lake charr-specific terminology is also presented. The book will be a valuable reference text for biologists around the world, ecologists, and fishery managers, and of interest to the angling public.
The Lakes of the Basin of Mexico: Dynamics of a Lacustrine System and the Evolution of a Civilization
by Carlos E. CordovaThis book is a review of research on the prehistoric and historic evolution of the Basin of Mexico’s lacustrine systems. Based on this review, the book presents a model of long and short-term natural lacustrine dynamics as the basis for understanding the processes of human adaptation and transformation of the aquatic ecosystems of the Basin of Mexico. Although only remains of the former lakes exist, the book stresses the importance of the knowledge of the former natural and cultural history of the lakes. In this sense, the book addresses the misconceptions and misinterpretations of the lakes that still exist in the literature and the media and that do not reflect the real nature of the lakes in the past. Therefore, the book attempts to not only feed into the local knowledge of the lakes, but also contribute to the worldwide knowledge of lacustrine dynamics and human populations that lived in and around them. The book should be of interest to geographers, geologists, archaeologists, natural historians and environmental scientists, civil engineers, city planners and those involved in the management of natural resources.
The Laminar Boundary Layer Equations (Dover Books on Physics)
by N. CurleA thorough introduction to the study of boundary layer problems in physics and fluid mechanics, this treatment assumes some knowledge of classical inviscid fluid dynamics. The ordered and logical presentation is accessible to undergraduates, and professionals will benefit from the careful expositions of the limitations and accuracy of various methods.An extensive introduction explains the boundary-layer concept and demonstrates its simplification of equations of viscous flow. Successive chapters address various aspects of solution in incompressible flow, starting with analytic solutions of the velocity field and advancing to discussions of high-accuracy numerical solutions, practical methods of calculation, and an analysis of factors that might govern the choice of a method. Several chapters on the compressible laminar boundary layer include examinations of pressure gradient and heat transfer, followed by a brief exploration of some aspects of the problem of the interaction between shock waves and laminar boundary layers. Complete references and a helpful Index conclude the text.
The Land Is Our Community: Aldo Leopold’s Environmental Ethic for the New Millennium
by Roberta L. MillsteinA contemporary defense of conservationist Aldo Leopold’s vision for human interaction with the environment. Informed by his experiences as a hunter, forester, wildlife manager, ecologist, conservationist, and professor, Aldo Leopold developed a view he called the land ethic. In a classic essay, published posthumously in A Sand County Almanac, Leopold advocated for an expansion of our ethical obligations beyond the purely human to include what he variously termed the “land community” or the “biotic community”—communities of interdependent humans, nonhuman animals, plants, soils, and waters, understood collectively. This philosophy has been extremely influential in environmental ethics as well as conservation biology and related fields. Using an approach grounded in environmental ethics and the history and philosophy of science, Roberta L. Millstein reexamines Leopold’s land ethic in light of contemporary ecology. Despite the enormous influence of the land ethic, it has sometimes been dismissed as either empirically out of date or ethically flawed. Millstein argues that these dismissals are based on problematic readings of Leopold’s ideas. In this book, she provides new interpretations of the central concepts underlying the land ethic: interdependence, land community, and land health. She also offers a fresh take on of his argument for extending our ethics to include land communities as well as Leopold-inspired guidelines for how the land ethic can steer conservation and restoration policy.
The Land/Ocean Interactions in the Coastal Zone of West and Central Africa
by Salif Diop Jean-Paul Barusseau Cyr DescampsAlthough the main focus of this book is on the estuaries, its scope goes well beyond this particular coastal feature. Indeed, the estuary can only be considered as part of the life cycle of the entire river and the marine area it feeds into: an area particularly subject to human and natural pressures. The main estuaries and deltas of West and Central Africa region provide a variety of goods and services to its coastal population. The most important of them are related to critical fish habitat, wood and charcoal from mangroves, as well as space for agriculture, aquaculture, urban development, tourism and transport. Particular emphasis has been made in this book on mangroves that play a significant role in terms of flood control, groundwater replenishment, coastline stabilization and protection against storms. They also retain sediments and nutrients, purify water, and provide critical carbon storage. Such hydrological and ecological functions explain the focus on serving mangrove ecosystems and the nearby communities, which draw significant income from fishing, rice production, tourism, salt extraction and other activities such as harvesting honey and medicinal plants, hence the need for preserving mangrove ecosystems to ensure sustainability of the estuaries and deltas of West and Central Africa region. The book has a foreword by Mr. Achim Steiner, United Nations Under-Secretary General and Executive Director of UNEP who is stating that credible and up-to-date information is essential for the public at large but more specifically for scientists, researchers, managers, decision-makers all working together in order to safeguard, protect and sustainably manage estuaries, deltas and lagoons, and the coastal and ocean waters of Western and Central Africa.
The Landscape Ecology of Fire
by Carol Miller Donald A. Falk Donald MckenzieGlobal warming is expected to change fire regimes, likely increasing the severity and extent of wildfires in many ecosystems around the world. What will be the landscape-scale effects of these altered fire regimes? Within what theoretical contexts can we accurately assess these effects? We explore the possible effects of altered fire regimes on landscape patch dynamics, dominant species (tree, shrub, or herbaceous) and succession, sensitive and invasive plant and animal species and communities, and ecosystem function. Ultimately, we must consider the human dimension: what are the policy and management implications of increased fire disturbance, and what are the implications for human communities?