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Unnatural Amino Acids

by Stefano Servi Loredano Pollegioni

Even though they are present in nature, non-proteinogenic amino acids are usually defined as unnatural or non-natural. Beside their structural diversity, interest in these compounds is due to their occurrence in nature, their biological properties, the analytical aspects, their use as probes, and their incorporation into peptides and proteins, among other reasons. Divided into five convenient sections, Unnatural Amino Acids: Methods and Protocols deals with enzymatic methods used to produce non-natural amino acids, aspects concerning the presence of unnatural amino acids in peptides with antimicrobial properties, genetic incorporation of unnatural amino acids into proteins (yeast and mammalian cells), and detection and quantification of D-amino acids and related enzymes. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Unnatural Amino Acids: Methods and Protocols serves as an ideal guide for scientists and contributes to directing the attention of researchers to the many fields of growing scientific interest in non-natural amino acids.

Unnatural Causes: 'An absolutely brilliant book. I really recommend it, I don't often say that' Jeremy Vine, BBC Radio 2

by Dr Richard Shepherd

THE TRUE CRIME BOOK OF THE YEAR AND 18-WEEK SUNDAY TIMES TOP 10 BESTSELLER'One of the most fascinating books I have read in a long time. Engrossing, a haunting page-turner. A book I could not put down' The Times, BOOKS OF THE YEAR__________Meet the forensic pathologist, Dr Richard Shepherd.He solves the mysteries of unexplained or sudden death.He has performed over 23,000 autopsies, including some of the most high-profile cases of recent times; the Hungerford Massacre, the Princess Diana inquiry, and 9/11. He has faced serial killers, natural disaster, 'perfect murders' and freak accidents.His evidence has put killers behind bars, freed the innocent, and turned open-and-shut cases on their heads. Yet all this has come at a huge personal cost. Unnatural Causes tells the story of not only the cases and bodies that have haunted him the most, but also how to live a life steeped in death. Thoughtful, revealing, chilling and always unputdownable, if you liked All That Remains, War Doctor and This is Going to Hurt you'll love this. **Pre-order Dr Richard Shepherd's new book THE SEVEN AGES OF DEATH now**__________'Gripping, grimly fascinating, and I suspect I'll read it at least twice' Evening Standard'A deeply mesmerising memoir of forensic pathology. Human and fascinating' Nigella Lawson 'An absolutely brilliant book. I really recommend it, I don't often say that but it's fascinating' Jeremy Vine, BBC Radio 2'Puts the reader at his elbow as he wields the scalpel' Guardian 'Fascinating, gruesome yet engrossing' Richard and Judy, Daily Express'Fascinating, insightful, candid, compassionate' Observer

Unnatural Death: Confessions Of A Medical Examiner

by Michael Baden Judith A. Hennesee

* JFK's autopsy failed to disclose crucial evidence. * The deaths of John Belushi and Elvis Presley were far more complex than anyone has let on. * Decisive medical findings in the von Bulow affair were consistently overlooked. These are but three of the shocking revelations in Dr. Michael Baden's first-person, no-holds-barred account of his distinguished career in forensic pathology. In determining the causes of tens of thousands of deaths, from those of presidents and rock stars to victims of serial killings, exotic sex rituals, mass disasters, child abuse and drug abuse, Baden has come to the unavoidable conclusion that the search for scientific truth is often sullied by the pressures of expediency. He produces dramatic evidence to demonstrate that political intrigue, influence peddling, and professional incompetence have created a national crisis in forensic medicine. "A fascinating look into the mechanics of forensics and a disconcerting lesson in the politics of death.

Unnatural Habitat: The Native and Exotic Wildlife of Los Angeles

by Craig Stanford

A guide to the ecosystem famously known as Los Angeles, from a field biologist and longtime San Gabriel Valley resident."A worthy and illuminating entry in the tradition of works exploring urbanization's effect on the environment." —Los Angeles TimesWithin the sprawling metropolis of Los Angeles and its suburbs, residents coexist—often unknowingly—with a bustling mosaic of native and introduced wildlife. Conservationist Craig Stanford, whose research has taken him around the world, now takes a deep dive into the natural history of his Southern California home. Stanford's informed and vivid accounts of more than 150 species entreat us to appreciate the ecological marvels of sagebrush and skunks and skippers, the iconic palms of LA lore, and the mountain lions still roaming the hills.These portraits of the glamorous, humble, irritating, and altogether fascinating species that live alongside Angelenos urge us to recognize that even in a jungle of concrete, we live within nature. Witty and captivating, and combining cutting-edge research with his own critter encounters, Stanford demonstrates the beauty of shaping our cities to support biodiversity, and he warns against the threats that can tip urban ecosystems out of balance, leaving us in a much lonelier world.

An Unnatural Metropolis: Wresting New Orleans from Nature

by Craig E. Colten

Strategically situated at the gateway to the Mississippi River yet standing atop a former swamp, New Orleans was from the first what geographer Peirce Lewis called an "impossible but inevitable city." How New Orleans came to be, taking shape between the mutual and often contradictory forces of nature and urban development, is the subject of An Unnatural Metropolis. Craig E. Colten traces engineered modifications to New Orleans's natural environment from 1800 to 2000 and demonstrates that, though all cities must contend with their physical settings, New Orleans may be the city most dependent on human-induced transformations of its precarious site. In a new preface, Colten shows how Hurricane Katrina exemplifies the inability of human artifice to exclude nature from cities and he urges city planners to keep the environment in mind as they contemplate New Orleans's future. Urban geographers frequently have portrayed cities as the antithesis of nature, but in An Unnatural Metropolis, Colten introduces a critical environmental perspective to the history of urban areas. His amply illustrated work offers an in-depth look at a city and society uniquely shaped by the natural forces it has sought to harness.

Unnatural Selection: The Challenges of Engineering Tomorrow's People (The Earthscan Science in Society Series)

by Peter Healey Steve Rayner

With ever-advancing scientific understanding and technological capabilities, humanity stands on the brink of the potential next stage of evolution: evolution engineered by us. Nanotechnology, biotechnology, information technology and cognitive science offer the possibility to enhance human performance, lengthen life-span and reshape our inherited physical, cognitive and emotional identities. But with this promise come huge risks, complex choices and fundamental ethical questions: about evolution; about what it is to be human; and about control over, and the distribution of benefits from, new technology. Written by a range of experts in science, technology, bioethics and social science, Unnatural Selection examines the range of technological innovations offering lives that purport to be longer, stronger, smarter and happier, and asks whether their introduction is likely to lead to more fulfilled individuals and a fairer world. The breadth of approaches and perspectives make important reading for anyone who cares about the implications of humanity engineering its own evolution.

Unnatural Selection: Choosing Boys Over Girls, and the Consequences of a World Full of Men

by Mara Hvistendahl

A shocking expos(r) of the causes of Asia's massive gender imbalance and its consequences across the globe

Unnatural Selection: How We Are Changing Life, Gene by Gene

by Emily Monosson

Gonorrhea. Bed bugs. Weeds. Salamanders. People. All are evolving, some surprisingly rapidly, in response to our chemical age. In Unnatural Selection, Emily Monosson shows how our drugs, pesticides, and pollution are exerting intense selection pressure on all manner of species. And we humans might not like the result. Monosson reveals that the very code of life is more fluid than once imagined. When our powerful chemicals put the pressure on to evolve or die, beneficial traits can sweep rapidly through a population. Species with explosive population growth--the bugs, bacteria, and weeds--tend to thrive, while bigger, slower-to-reproduce creatures, like ourselves, are more likely to succumb. Monosson explores contemporary evolution in all its guises. She examines the species that we are actively trying to beat back, from agricultural pests to life-threatening bacteria, and those that are collateral damage--creatures struggling to adapt to a polluted world. Monosson also presents cutting-edge science on gene expression, showing how environmental stressors are leaving their mark on plants, animals, and possibly humans for generations to come. Unnatural Selection is eye-opening and more than a little disquieting. But it also suggests how we might lessen our impact: manage pests without creating super bugs; protect individuals from disease without inviting epidemics; and benefit from technology without threatening the health of our children.

Unnatural Selection: Why the Geeks Will Inherit the Earth

by Mark Roeder

Unnatural Selection is the first book to examine the rise of the "technocentric being"-or geek-who personifies a distinct new phase in human evolution. People considered geeks often have behavioral or genetic traits that were previously considered detrimental. But the new environment of the Anthropocene period-the Age of Man-has created a kind of digital greenhouse that actually favors their traits, enabling many non-neurotypical people to bloom. They resonate with the technological Zeitgeist in a way that turns their weaknesses into strengths. Think of Mark Zuckerberg versus the towering, Olympics-bound Winklevoss twins in the movie Social Network.Roeder suggests that the rise of the geek is not so much the product of Darwinian "natural selection" as of man-made-or unnatural-selection. He explains why geeks have become so phenomenally successful in such a short time and why the process will further accelerate, driven by breakthroughs in genetic engineering, neuropharmacology, and artificial intelligence. His book offers a fascinating synthesis of the latest trends in these fields and predicts a twenty-first century "cognitive arms race" in which new technology will enable everyone to become more intelligent and "geek-like."

The Unpersuadables: Adventures with the Enemies of Science

by Will Storr

While excavating fossils in the tropics of Australia with a celebrity creationist, Will Storr asked himself a simple question. Why don't facts work? Why, that is, did the obviously intelligent man beside him sincerely believe in Adam and Eve, the Garden of Eden and a six-thousand-year-old Earth, in spite of the evidence against them? It was the start of a journey that would lead Storr all over the world--from Texas to Warsaw to the Outer Hebrides--meeting an extraordinary cast of modern heretics whom he tries his best to understand. Storr tours Holocaust sites with famed denier David Irving and a band of neo-Nazis, experiences his own murder during "past life regression" hypnosis, discusses the looming One World Government an iconic climate skeptic, and investigates the tragic life and death of a woman who believed her parents were high priests in a baby-eating cult. Using a unique mix of highly personal memoir, investigative journalism, and the latest research from neuroscience and experimental psychology, Storr reveals how the stories we tell ourselves about the world invisibly shape our beliefs, and how the neurological "hero maker" inside us all can so easily lead to self-deception, toxic partisanship and science denial.

The Unpredictable Certainty: Information Infrastructure Through 2000

by NII 2000 Steering Committee

We have available an impressive array of information technology. We can transmit literature, movies, music, and talk. Government, businesses, and individuals are eager to go on-line to buy, sell, teach, learn, and more. How, then, should we go about developing an infrastructure for on- line communication among everyone everywhere? The Unpredictable Certainty explores the national information infrastructure (NII) as the collection of all public and private information services. But how and when will the NII become a reality? How will more and better services reach the home, small businesses, and remote locations? The Unpredictable Certainty examines who will finance the NII, exploring how technology companies decide to invest in deployment and the the vain search for "killer apps" (applications that drive markets). It discusses who will pay for ongoing services and how they will pay, looking at past cost/price models relevant to the future. The Unpredictable Certainty discusses the underlying technologies, appliances, and services needed before the NII becomes a reality; reviews key features of important technologies; and analyzes current levels of deployment in telephone, cable and broadcast television, and wireless systems, and the difficulties in interconnection. The volume explores the challenge of open interfaces that stimulate new applications but also facilitate competition, the trend toward the separation of infrastructure from specific services, the tension between mature services and new contenders, the growth of the Internet, and more. The roles governments at different levels might play in fostering NII deployment are outlined, including R&D and the use of information infrastructure for better delivery of government services and information.

The Unpredictable Species: What Makes Humans Unique

by Philip Lieberman

How our brains have evolved so that we control how we think and behaveThe Unpredictable Species argues that the human brain evolved in a way that enhances our cognitive flexibility and capacity for innovation and imitation. In doing so, the book challenges the central claim of evolutionary psychology that we are locked into predictable patterns of behavior that were fixed by genes, and refutes the claim that language is innate. Philip Lieberman builds his case with evidence from neuroscience, genetics, and physical anthropology, showing how our basal ganglia—structures deep within the brain whose origins predate the dinosaurs—came to play a key role in human creativity. He demonstrates how the transfer of information in these structures was enhanced by genetic mutation and evolution, giving rise to supercharged neural circuits linking activity in different parts of the brain. Human invention, expressed in different epochs and locales in the form of stone tools, digital computers, new art forms, complex civilizations—even the latest fashions—stems from these supercharged circuits.The Unpredictable Species boldly upends scientifically controversial yet popular beliefs about how our brains actually work. Along the way, this compelling book provides insights into a host of topics related to human cognition, including associative learning, epigenetics, the skills required to be a samurai, and the causes of cognitive confusion on Mount Everest and of Parkinson's disease.

Unquenchable: America's Water Crisis and What To Do About It

by Robert Jerome Glennon

In the middle of the Mojave Desert, Las Vegas casinos use billions of gallons of water for fountains, pirate lagoons, wave machines, and indoor canals. Meanwhile, the town of Orme, Tennessee, must truck in water from Alabama because it has literally run out. Robert Glennon captures the irony--and tragedy--of America's water crisis in a book that is both frightening and wickedly comical. From manufactured snow for tourists in Atlanta to trillions of gallons of water flushed down the toilet each year, Unquenchable reveals the heady extravagances and everyday inefficiencies that are sucking the nation dry. The looming catastrophe remains hidden as government diverts supplies from one area to another to keep water flowing from the tap. But sooner rather than later, the shell game has to end. And when it does, shortages will threaten not only the environment, but every aspect of American life: we face shuttered power plants and jobless workers, decimated fi sheries and contaminated drinking water. We can't engineer our way out of the problem, either with traditional fixes or zany schemes to tow icebergs from Alaska. In fact, new demands for water, particularly the enormous supply needed for ethanol and energy production, will only worsen the crisis. America must make hard choices--and Glennon's answers are fittingly provocative. He proposes market-based solutions that value water as both a commodity and a fundamental human right. One truth runs throughout Unquenchable: only when we recognize water's worth will we begin to conserve it.

Unraveling New Frontiers and Advances in Bioinformatics

by Amit Chaudhary Sushanta K. Sethi Akarsh Verma

This book describes the bioinformatics research field, from its historical roots to the cutting-edge technologies. Many readers can discover the power of next-generation sequencing and genomic data analysis, uncover the secrets of single-cell genomics and transcriptomics, explore the metagenomics and microbiome analysis, and predict the protein structures using structural bioinformatics. Several case studies witnessing the fusion of bioinformatics and artificial intelligence, driving insights from vast biological datasets have also been explored. Other important aspects listed in the book are integrating the omics data for a holistic view of biological systems; experiencing the future of medicine with precision healthcare and personalized treatments; accelerating drug discovery and repurposing through computational approaches; agricultural genomics; and exploring the role of immunoinformatics in designing effective vaccines against infectious diseases.

Unraveling the Voynich Codex (Fascinating Life Sciences)

by Arthur O. Tucker Jules Janick

Unraveling the Voynich Codex reviews the historical, botanical, zoological, and iconographic evidence related to the Voynich Codex, one of the most enigmatic historic texts of all time. The bizarre Voynich Codex has often been referred to as the most mysterious book in the world. Discovered in an Italian Catholic college in 1912 by a Polish book dealer Wilfrid Voynich, it was eventually bequeathed to the Beinecke Rare Book and Manuscript Library of Yale University. It contains symbolic language that has defied translation by eminent cryptologists. The codex is encyclopedic in scope and contains sections known as herbal, pharmaceutical, balenological (nude nymphs bathing in pools), astrological, cosmological and a final section of text that may be prescriptions but could be poetry or incantations. Because the vellum has been carbon dated to the early 15th century and the manuscript was known to be in the collection of Emperor Rudolf II of the Holy Roman Empire sometime between 1607 and 1622, current dogma had assumed it a European manuscript of the 15th century. However, based on identification of New World plants, animals, a mineral, as well as cities and volcanos of Central Mexico, the authors of this book reveal that the codex is clearly a document of colonial New Spain. Furthermore, the illustrator and author are identified as native to Mesoamerica based on a name and ligated initials in the first botanical illustration. This breakthrough in Voynich studies indicates that the failure to decipher the manuscript has been the result of a basic misinterpretation of its origin in time and place. Tentative assignment of the Voynichese symbols also provides a key to decipherment based on Mesoamerican languages. A document from this time, free from filter or censor from either Spanish or Inquisitorial authorities has major importance in our understanding of life in 16th century Mexico. Publisher's Note: For the eBook editions, Voynichese symbols are only rendered properly in the PDF format.

Unraveling Thermoluminescence

by C M Sunta

The book is essentially about the theoretical aspects of thermoluminescence (TL). It is structured and written in a manner which will specially be of interest to the fresh undergraduate students and young researchers planning to take up work in the field of thermoluminescence. It is arranged into seven chapters, starting with the historical growth of the subject of TL and an overview of the luminescence phenomena. A Physical model involving thermally disconnected deep traps is specially described. Using this model expressions are derived for the TL intensity growth curve, the supralinearity factor and the pre-dose sensitization factor. A new factor, called the sensitization factor is introduced which co-relates the supralinearity and the pre-dose sensitization factors. Dealing with the theoretical models of TL, limitations of the general order (GO) kinetics and the mixed order kinetics models are specially brought out. Due to the lacunae of GO model the determination of activation energy becomes subject to error, when GO model is applied to the experimental TL glow curves. Satisfying the quasi-equilibrium (QE) condition is essential for the validity of analytical models of TL. A new method is given to ascertain if QE condition is satisfied in an experimental glow curve. The book assumes a basic knowledge of physics and mathematics at an undergraduate level and takes the reader to the results at the cutting edge of understanding of the subject in an easy to understand manner.

Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach

by Kakoli Bose Pradip Chaudhari

Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth.

Unravelling Long COVID

by Don Goldenberg Marc Dichter

Unravelling Long COVID An authoritative medical reference on the various ways in which Long-COVID presents and an in-depth discussion of its mechanisms and potential therapeutic options. Unravelling Long COVID aims to provide a better awareness and understanding of the persistent health problems that can arise following SARS-CoV-2 infection. Variously described as Long-COVID, Long-Haulers’ Syndrome, and Post-Acute Sequelae of SARS-CoV-2, this newly-designated disorder is estimated to have affected somewhere between 50 to 250 million people. It is in fact considered by many as the next global public health disaster. With such a broad and important topic, the authors of Unravelling Long COVID have focused primarily on two major problems in the current understanding of Long-COVID: 1.) the failure to distinguish patients with organ damage—here called Long-COVID Disease – and those with unexplained, persistent symptoms—what is termed Long-COVID syndrome, and 2.) the failure of current medical approaches to comprehend and treat those persistent unexplained symptoms. Unravelling Long COVID is: One of the first books focused specifically on defining and understanding Long-COVID with the goal of establishing optimal management A unique reference to distinguish patients with organ damage caused by Long-COVID disease from those with unexplained, persistent symptoms that manifest as Long-COVID syndrome An in-depth exploration of neuroimmune pathways to help clarify the previously unexplained symptoms of Long-COVID Unravelling Long COVID is an essential reference for anyone interested in Long-COVID and the impact that this condition has had on the population. It will be a useful resource for both patients suffering from the Long-Covid syndrome, their physicians and for the growing number of Long-COVID clinics that have been established across the US, the UK, and other countries.

Unravelling the Double Helix: The Lost Heroes Of Dna

by Gareth Williams

An insightful history of the first hundred years of DNA, Unraveling The Double Helix tells the story one of the greatest triumphs of modern science. Unraveling the Double Helix covers the most colorful period in the history of DNA, from the discovery of "nuclein" in the late 1860s to the publication of James Watson's The Double Helix in 1968. These hundred years included the establishment of the Nobel Prize, antibiotics, x-ray crystallography, the atom bomb and two devastating world wars—events which are strung along the thread of DNA like beads on a necklace. The story of DNA is a saga packed with awful mistakes as well as brilliant science, with a wonderful cast of heroes and villains. Surprisingly, much of it is unfamiliar. The elucidation of the double helix was one of the most brilliant gems of twentieth century science, but some of the scientists who paved the way have been airbrushed out of history. James Watson and Francis Crick solved a magnificent mystery, but Gareth Williams shows that their contribution was the last few pieces of a gigantic jigsaw puzzle assembled over several decades. The book is comprehensive in scope, covering the first century of the history of DNA in its entirety, including the eight decades that have been neglected by other authors. It also explores the personalities of the main players, the impact of their entanglement with DNA, and what unique qualities make great scientists tick.

Unravelling the Double Helix: The Lost Heroes of DNA

by Gareth Williams

DNA. The double helix; the blueprint of life; and, during the early 1950s, a baffling enigma that could win a Nobel Prize. Everyone knows that James Watson and Francis Crick discovered the double helix. In fact, they clicked into place the last piece of a huge jigsaw puzzle that other researchers had assembled over decades. Researchers like Maurice Wilkins (the 'Third Man of DNA') and Rosalind Franklin, famously demonised by Watson. Not forgetting the 'lost heroes' who fought to prove that DNA is the stuff of genes, only to be airbrushed out of history. In Unravelling the Double Helix, Professor Gareth Williams sets the record straight. He tells the story of DNA in the round, from its discovery in pus-soaked bandages in 1868 to the aftermath of Watson's best-seller The Double Helix a century later. You don't need to be a scientist to enjoy this book. It's a page-turner that unfolds like a detective story, with suspense, false leads and treachery, and a fabulous cast of noble heroes and back-stabbing villains. But beware: some of the science is dreadful, and the heroes and villains may not be the ones you expect.

Unravelling the Double Helix: The Lost Heroes of DNA

by Gareth Williams

DNA. The double helix; the blueprint of life; and, during the early 1950s, a baffling enigma that could win a Nobel Prize. Everyone knows that James Watson and Francis Crick discovered the double helix. In fact, they clicked into place the last piece of a huge jigsaw puzzle that other researchers had assembled over decades. Researchers like Maurice Wilkins (the 'Third Man of DNA') and Rosalind Franklin, famously demonised by Watson. Not forgetting the 'lost heroes' who fought to prove that DNA is the stuff of genes, only to be airbrushed out of history. In Unravelling the Double Helix, Professor Gareth Williams sets the record straight. He tells the story of DNA in the round, from its discovery in pus-soaked bandages in 1868 to the aftermath of Watson's best-seller The Double Helix a century later. You don't need to be a scientist to enjoy this book. It's a page-turner that unfolds like a detective story, with suspense, false leads and treachery, and a fabulous cast of noble heroes and back-stabbing villains. But beware: some of the science is dreadful, and the heroes and villains may not be the ones you expect.

Unravelling the Double Helix: The Lost Heroes of DNA

by Gareth Williams

DNA. The double helix; the blueprint of life; and, during the early 1950s, a baffling enigma that could win a Nobel Prize. Everyone knows that James Watson and Francis Crick discovered the double helix. In fact, they clicked into place the last piece of a huge jigsaw puzzle that other researchers had assembled over decades. Researchers like Maurice Wilkins (the 'Third Man of DNA') and Rosalind Franklin, famously demonised by Watson. Not forgetting the 'lost heroes' who fought to prove that DNA is the stuff of genes, only to be airbrushed out of history. In Unravelling the Double Helix, Professor Gareth Williams sets the record straight. He tells the story of DNA in the round, from its discovery in pus-soaked bandages in 1868 to the aftermath of Watson's best-seller The Double Helix a century later. You don't need to be a scientist to enjoy this book. It's a page-turner that unfolds like a detective story, with suspense, false leads and treachery, and a fabulous cast of noble heroes and back-stabbing villains. But beware: some of the science is dreadful, and the heroes and villains may not be the ones you expect.

Unravelling the Soil Microbiome: Perspectives For Environmental Sustainability (SpringerBriefs in Environmental Science)

by Rama Kant Dubey Vishal Tripathi Ratna Prabha Rajan Chaurasia Dhananjaya Pratap Singh Ch. Srinivasa Rao Ali El-Keblawy Purushothaman Chirakkuzhyil Abhilash

This book explores the significance of soil microbial diversity to understand its utility in soil functions, ecosystem services, environmental sustainability, and achieving the sustainable development goals. With a focus on agriculture and environment, the book highlights the importance of the microbial world by providing state-of-the-art technologies for examining the structural and functional attributes of soil microbial diversity for applications in healthcare, industrial biotechnology, and bioremediation studies. In seven chapters, the book will act as a primer for students, environmental biotechnologists, microbial ecologists, plant scientists, and agricultural microbiologists. Chapter 1 introduces readers to the soil microbiome, and chapter 2 discusses the below ground microbial world. Chapter 3 addresses various methods for exploring microbial diversity, chapter 4 discusses the genomics methods, chapter 5 provides the metaproteomics and metatranscriptomics approaches and chapter 6 details the bioinformatics tools for soil microbial community analysis, and chapter 7 concludes the text with future perspectives on further soil microbial uses and applications.

An Unreasonable Woman: A True Story of Shrimpers, Políticos, Polluters, and the Fight for Seadrift, Texas

by Diane Wilson

For her activism on behalf of Texas Gulf Coast bays, Wilson has been recognized with awards including Mother Jones' Hellraiser of the Month. In her first book, this fourth-generation shrimper relates her battles against a plastics company (and their political allies) whose dumping of toxic chemicals resulted in her county's designation as the nation's most polluted in the late 1980s. Annotation ©2005 Book News, Inc., Portland, OR (booknews.com)

The Unreliable Nation: Hostile Nature and Technological Failure in the Cold War (Inside Technology)

by Edward Jones-Imhotep

An examination of how technological failures defined nature and national identity in Cold War Canada.Throughout the modern period, nations defined themselves through the relationship between nature and machines. Many cast themselves as a triumph of technology over the forces of climate, geography, and environment. Some, however, crafted a powerful alternative identity: they defined themselves not through the triumph of machines over nature, but through technological failures and the distinctive natural orders that caused them. In The Unreliable Nation, Edward Jones-Imhotep examines one instance in this larger history: the Cold War–era project to extend reliable radio communications to the remote and strategically sensitive Canadian North. He argues that, particularly at moments when countries viewed themselves as marginal or threatened, the identity of the modern nation emerged as a scientifically articulated relationship between distinctive natural phenomena and the problematic behaviors of complex groups of machines.Drawing on previously unpublished archival documents and recently declassified materials, Jones-Imhotep shows how Canadian defense scientists elaborated a distinctive “Northern” natural order of violent ionospheric storms and auroral displays, and linked it to a “machinic order” of severe and widespread radio disruptions throughout the country. Tracking their efforts through scientific images, experimental satellites, clandestine maps, and machine architectures, he argues that these scientists naturalized Canada's technological vulnerabilities as part of a program to reimagine the postwar nation. The real and potential failures of machines came to define Canada, its hostile Northern nature, its cultural anxieties, and its geo-political vulnerabilities during the early Cold War. Jones-Imhotep's study illustrates the surprising role of technological failures in shaping contemporary understandings of both nature and nation.

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