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The Metabolic Pathway Engineering Handbook: Fundamentals
by Christina D. SmolkeThis first volume of the Metabolic Pathway Engineering Handbook provides an overview of metabolic pathway engineering with a look towards the future. It discusses cellular metabolism, including transport processes inside the cell and energy generating reactions, as well as rare metabolic conversions. This volume also explores balances and reaction
The Metabolic Pathway Engineering Handbook: Tools and Applications
by Christina D. SmolkeThis second volume of the Metabolic Pathway Engineering Handbook delves into evolutionary tools and gene expression tools for metabolic pathway engineering. It covers applications of emerging technologies including recent research genome-wide technologies, DNA and phenotypic microarrays, and proteomics tools for experimentally determining flux thro
The Metabolism of Arsenite (Arsenic in the environment)
by Joanne M. Santini; Seamus A. WardUp to 200 million people in 70 countries are at risk from drinking water contaminated with arsenic, which is a major cause of chronic debilitating illnesses and fatal cancers. Until recently little was known about the mobility of arsenic, and how redox transformations determined its movement into or out of water supplies. Although human activities contribute to the release of arsenic from minerals, it is now clear that bacteria are responsible for most of the redox transformation of arsenic in the environment. Bacterial oxidation of arsenite (to the less mobile arsenate) has been known since 1918, but it was not until 2000 that a bacterium was shown to gain energy from this process. Since then a wide range of arsenite-oxidizing bacteria have been isolated, including aerobes and anaerobes; heterotrophs and autotrophs; thermophiles, mesophiles and psychrophiles. This book reviews recent advances in the study of such bacteria. After a section on background—geology and health issues—the main body of the book concerns the cellular machinery of arsenite oxidation. It concludes by examining possible applications. Topics treated are: The geology and cycling of arsenic Arsenic and disease Arsenite oxidation: physiology, enzymes, genes, and gene regulation. Community genomics and functioning, and the evolution of arsenite oxidation Microbial arsenite oxidation in bioremediation Biosensors for arsenic in drinking water and industrial effluents
The Metamorphoses of the Brain - Neurologisation and its Discontents
by Jan De VosWhat are we exactly, when we are said to be our brain? This question leads Jan De Vos to examine the different metamorphoses of the brain: the educated brain, the material brain, the iconographic brain, the sexual brain, the celebrated brain and, finally, the political brain. This first, protracted and sustained argument on neurologisation, which lays bare its lineage with psychologisation, should be taken seriously by psychologists, educationalists, sociologists, students of cultural studies, policy makers and, above all, neuroscientists themselves.
The Metaphysical Foundations of Modern Science
by E. A. BurttTo the medieval thinker, man was the center of creation and all of nature existed purely for his benefit. The shift from the philosophy of the Middle Ages to the modern view of humanity’s less central place in the universe ranks as the greatest revolution in the history of Western thought, and this classic in the philosophy of science describes and analyzes how that profound change occurred. A fascinating analysis of the works of Copernicus, Kepler, Galileo, Descartes, Hobbes, Gilbert, Boyle, and Newton, it not only establishes the reasons for the triumph of the modern perspective, but also accounts for certain limitations in this view that continue to characterize contemporary scientific thought. A criticism as well as a history of the change that made possible the rise of modern science, this volume is also a guide to understanding the methods and accomplishments of the great philosopher-scientists of the sixteenth and seventeenth centuries.
The Metaphysics and Mathematics of Arbitrary Objects
by Leon HorstenBuilding on the seminal work of Kit Fine in the 1980s, Leon Horsten here develops a new theory of arbitrary entities. He connects this theory to issues and debates in metaphysics, logic, and contemporary philosophy of mathematics, investigating the relation between specific and arbitrary objects and between specific and arbitrary systems of objects. His book shows how this innovative theory is highly applicable to problems in the philosophy of arithmetic, and explores in particular how arbitrary objects can engage with the nineteenth-century concept of variable mathematical quantities, how they are relevant for debates around mathematical structuralism, and how they can help our understanding of the concept of random variables in statistics. This fully worked through theory will open up new avenues within philosophy of mathematics, bringing in the work of other philosophers such as Saul Kripke, and providing new insights into the development of the foundations of mathematics from the eighteenth century to the present day.
The Metaphysics of Henry More
by Jasper ReidThe book surveys the key metaphysical contributions of the Cambridge Platonist, Henry More (1614-1687). It deals with such interwoven topics as: the natures of body and spirit, and the question of whether or not there is a sharp ontological division between them; the nature of spatial extension in relation to each; the composition and governance of the physical world, including More's theories of Hyle, atoms, vacuum, and the Spirit of Nature; and the life of the human soul, including its pre-existence. It approaches these topics and the systematic connections between them both historically and analytically, and seeks to do justice to the ways in which More's system developed and changed--sometimes quite dramatically--over the course of his long career. It also explores More's intellectual relations with both his own inspirations (Plotinus, Origen, Ficino, Descartes, etc.) and with those who responded, whether positively or negatively, to his work (Leibniz, Locke, Boyle, Newton, etc.).
The Metaphysics of Michael Polanyi: Toward a Post-Critical Platonism
by Martin E. Turkis IIThis book tells the story of how the Platonic vision of Michael Polanyi – the Hungarian-British chemist and philosopher – bridges the gap between speculative metaphysics and scientific practice, thus making sense of the broad swathe of human experience in a phenomenologically satisfying fashion. The central proposal is that Polanyi is a Platonist due to his affirmation of the ontological status of abstract objects, with particular focus placed on the question of uninstantiated universals. The book engages contemporary, speculative realists from both continental and analytic traditions as it introduces Polanyi’s influential epistemology and unpacks the fascinating metaphysics implied thereby. It then proceeds to develop Polanyi’s rather unsystematic metaphysics into a coherent, post-critical Platonism which incorporates his well-known theory of tacit knowledge, thus achieving something akin to the ancient Neoplatonic synthesis of Plato and Aristotle in our contemporary, scientific context.
The Metaverse for Learning and Education
by Maggi Savin-Baden David BurdenAccompanying The Metaverse: A Critical Introduction in CRC Press’ new The Metaverse Series, this book explores the ways in which the Metaverse can be used for education and learning, as well as how it is different from virtual reality (VR) application development. For example, institutions and tutors can make use of the Metaverse space to represent themselves in it or create their own content and share experiences, whilst students can access a wider range of material, learn within appropriate settings and create content to support their own and others’ learning.Key Features:• Provides practical advice from the authors’ collective three decades of work and experience in VR and Metaverse learning and education.• Examines different approaches to learning that are relevant in a VR and Metaverse context, including theoretical and practical approaches to pedagogy.• Suggests different approaches to learning that might be used and explores learning in practice in the metaverse – from early versions such as computer-supported collaborative learning and action learning through to more recent practices such as games and gamification and the use of problem-based learning in virtual worlds.• Examines a number of advantages of learning in the metaverse such as the opportunity to be inclusive towards different approaches to learning, the value of affordances, peer-to-peer learning and genres of participation.This book is aimed primarily at practitioners in the learning and education field, and those who set policy and commission work. It may also be of interest to parents, managers, other interested professionals, students, researchers and lay readers.
The Metaverse of Consciousness: Mapping the Multiple Dimensions of Reality
by Shelli Renée Joye• Develops the concept of the metaverse, the &“transcendental universe,&” composed of additional hidden dimensions operating in parallel with space and time• Integrates and maps the theories of consciousness developed by Carl Jung, David Bohm, Pierre Teilhard de Chardin, and other scientists• Offers the reader a path into the hidden dimensions through detailed maps of psyche, mind, and cosmosThe "metaverse"—as this wider universe is now coming to be known—is rooted in one interconnected consciousness that encompasses space and time as well as previously unknown dimensions only recently detected. In this book, Shelli Renée Joye, Ph.D., offers ways in which to visualize, enter, and explore a multitude of these transcendent, nonspatial, and nontemporal states and stages of consciousness as she reveals vast webs of interlinked consciousness forming a single universal psyche.Joye integrates the ideas of modern scientist-philosophers who view reality as a projection of a single multidimensional consciousness: Carl Jung and his concept of the psychoids, Pierre Teilhard de Chardin and his vision of an integrated noosphere of consciousness, and the quantum maps of consciousness developed by Karl Pribram and David Bohm. The book culminates with a call to explore transcendental consciousness by developing and following our own uniquely personal paths with which we too can enter the wider dimensions of awareness in the metaverse.
The Metaverse: A Critical Assessment (SpringerBriefs in Ethics)
by Philip BreyThis book offers an extensive assessment of the nature and feasibility of the metaverse and is the first to critically examine its social and ethical implications. The metaverse is, in essence, an envisioned future merger of virtual and augmented reality (VR and AR) and the internet, enabling real-time immersive interaction and activities like work, play, socializing, and entertainment. Major tech companies like Meta, Microsoft, Apple and NVIDIA have been investing billions in metaverse technologies, with generative AI accelerating progress. This book examines how these efforts could culminate in the metaverse, exploring its potential forms, implications, and the social and ethical challenges it may pose—along with recommendations for responsible innovation. The book is aimed at stakeholders shaping the metaverse—developers, creators, investors, business leaders, and thought leaders in technologies like VR, AR, Web3, blockchain, and AI. It also serves scholars and students in applied ethics, the social sciences, and the humanities, including fields such as media studies, psychology, and law. General readers interested in the metaverse and emerging technologies will find it both accessible and engaging. Endorsements: "In this book, the talented and eloquent philosopher Philip Brey carefully explains the history and ideas behind the metaverse, and the prospects for its further development and adoption. That detailed information, meticulously presented, makes this a valuable read. But that is just the start. In later chapters, Brey just as skillfully describes the opportunities and vulnerabilities that a metaverse is likely to generate. These chapters are thorough, precise, and offer profound insights into our possible futures. Some of the possibilities are exciting. Others are frightening." –Keith W. Miller, University of Missouri–St. Louis.
The Metaverse: And How It Will Revolutionize Everything
by Matthew BallINTERNATIONAL BESTSELLER — United States, Canada, United Kingdom, and China (Wall Street Journal, Associated Press, Nielsen Bookscan, Publishers Weekly, USA Today, Toronto Star, Globe & Mail, BookNet Canada, Bookseller.com, Bookdao/Nielsen, JD, DangDang) Tim Sweeney (CEO of Fortnite-maker Epic Games): “Matthew Ball’s essays have defined, analyzed, and inspired the Metaverse for years. His book is an approachable and essential guide to the strategic, technical, and philosophical foundations of this new medium.” Derek Thompson (Atlantic staff writer and national best-selling author of Hit Makers): “This book feels like a rare achievement: a definitive statement about an emerging phenomenon that could shape the digital world, the global economy, and the very experience of human consciousness.” From the leading theorist of the Metaverse comes the definitive account of the next internet: what the Metaverse is, what it will take to build it, and what it means for all of us. The term “Metaverse” is suddenly everywhere, from the front pages of national newspapers and the latest fashion trends to the plans of the most powerful companies in history. It is already shaping the policy platforms of the US government, the European Union, and the Chinese Communist Party. But what, exactly, is the Metaverse? As pioneering theorist and venture capitalist Matthew Ball explains, it is a persistent and interconnected network of 3D virtual worlds that will eventually serve as the gateway to most online experiences, and also underpin much of the physical world. For decades, these ideas have been limited to science fiction and video games, but they are now poised to revolutionize every industry and function, from finance and healthcare to education, consumer products, city planning, dating, and well beyond. Taking us on an expansive tour of the “next internet,” Ball demonstrates that many proto-Metaverses are already here, such as Fortnite, Minecraft, and Roblox. Yet these offer only a glimpse of what is to come. Ball presents a comprehensive definition of the Metaverse before explaining the technologies that will power it—and the breakthroughs that will be necessary to fully realize it. He addresses the governance challenges the Metaverse entails; investigates the role of Web3, blockchains, and NFTs; and predicts Metaverse winners and losers. Most importantly, he examines many of the Metaverse’s almost unlimited applications. The internet will no longer be at arm’s length; instead, it will surround us, with much of our lives, labor, and leisure taking place inside the Metaverse. Bringing clarity and authority to a frequently misunderstood concept, Ball foresees trillions of dollars in new value—and the radical reshaping of society.
The Metaverse: Fully Revised and Updated Edition: Building the Spatial Internet
by Matthew BallFrom the leading theorist of the Metaverse comes the eagerly anticipated, revised and updated account of the next internet: what the Metaverse is, what it will take to build it, and what it means for all of us. A Hudson Booksellers, Amazon, Guardian, Financial Times, Economist, and ByteDance Toutiao Best Book of the Year In this substantially revised and updated edition of his internationally best-selling book, pioneering theorist and entrepreneur Matthew Ball goes beyond the hype cycle to present a definitive account of the future of the internet. The Metaverse, according to Ball’s industry-shaping definition, is a persistent and interconnected network of 3D virtual worlds that will eventually serve as the gateway to most online experiences and underpin much of the physical world. As Ball recounts, the Metaverse is a thirty-year-old term, and the core ideas and technologies behind it have been in development for nearly a century. Only recently, however, did this fantastical concept begin to leap from the pages of science fiction and depths of national research labs to the forefront of consumer technology, industrial engineering, healthcare, education, dating, and more. From the history of video games and virtual reality to “proto-metaverses” such as Second Life, Fortnite, and Roblox to Generative AI and the groundbreaking films and television series of the Walt Disney Company, Ball points out that the Metaverse is already emerging around us (and doesn’t require a headset). Still, there are many breakthroughs required to fully realize the Metaverse, and he describes each in approachable but expert detail. Ball also lays out how governmental policy, the philosophy of Big Tech leaders, artificial general intelligence, economics, and human rights will shape the development of the Metaverse. Famous for his ability to bring clarity to complex and misunderstood topics, Ball demonstrates that the race to build the Metaverse—also known as the “spatial” or “immersive” internet—is only accelerating. The Metaverse will endure as an indispensable guide for enthusiasts, tech aficionados, and anyone curious about the profound transformations underway in our increasingly interconnected world.
The Meteorite Hunters: On the Trail of Extraterrestrial Treasures and the Secrets Inside Them
by Joshua HowgegoWant to join the ultimate cosmic treasure hunt? 'They fall from the sky, and tell us about the universe: a passionate story of the excitement and the science of searching for and deciphering meteorites.' Carlo Rovelli Meteors, with their ethereal, glowing trails slashing through the atmosphere, have entranced us for centuries. But these extraterrestrial visitors are also inestimably valuable. Not just for collectors, who can make their fortunes tracking them down, but for scientists too. Meteorites are the most ancient objects we know, unblemished time capsules from the birth of the solar system. Following in the footsteps of passionate hobbyists, ground-breaking scientists and intrepid adventurers, Joshua Howgego takes a rollicking ride through the world of meteorite hunting. Join the seasoned practitioners braving the elements as they scour the Sahara and ice sheets of Antarctica. Discover how, closer to home, one unlikely hero – a self-taught jazz guitarist – is uncovering the countless micrometeorites scattered across the rooftops of our cities. And meet the professor searching for the rarest of the rare: fossil meteorites, entombed in rock since the days of the dinosaurs. Finding these stones from space is just the beginning. As scientists tease out their secrets, they piece together an unexpected new history of the solar system, with implications that extend to one of the most fundamental questions we can ask: how did life on earth begin?
The Methodological Heritage of Newton
by Robert E. Butts John W. DavisIn recent years there has been a resurgence of interest in Newton and his influence. His thought, like that of Aristotle and every other great thinker, underwent development which contemporary scholars are seeking to understand more clearly than did their predecessors, awed as they were by the overwhelming Newtonian achievement.As the titles indicate, the range of essays included in this volume is wide, but most are concerned not so much with explaining Newton's development as with assessing his contribution to the thought of others. They explore all aspects of the conceptual background--historical, philosophical, and narrowly methodological--and examine questions that developed in the wake of Newton's science. The papers are varied yet unified in their attention to common themes and show the wealth of philosophical matter to be found in scientific synthesis. Newton left a rich complexity of philosophical problems whose attempted resolution helps our understanding both of method and positive science. His theories are one of the greatest achievements in physics; they are also valuable case studies for those interested in grasping the methodological and broadly philosophical basis of science. Four of the seven essays in this volume were prepared for an international conference held at the University of Western Ontario in April 1967; the three other papers were added by the editors to supplement and unify the collection.
The Mexican Profit-Sharing Decision: Politics in an Authoritarian Regime
by Susan Kaufman PurcellThis title is part of UC Press's Voices Revived program, which commemorates University of California Press’s mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1975.
The Mexican Transition Zone: A Natural Biogeographic Laboratory to Study Biotic Assembly
by Juan J. MorroneThis book presents an evolutionary biogeographic analysis of the Mexican Transition Zone, which is situated in the overlap of the Nearctic and Neotropical regions. It includes a comprehensive review of previous track, cladistic and molecular biogeographic analyses and is illustrated with full color maps and vegetation photographs of the respective areas covered. Given its scope, the book will be of interest to students and researchers whose work involves systematic and biogeographic analyses of plant and animal taxa of the Mexican Transition Zone or other transition zones of the world, and to ecologists working in biodiversity conservation, who will be able to appreciate the evolutionary relevance of the Mexican Transition Zone for establishing conservation areas..
The Meyers Neuropsychological Battery: A Comprehensive Systems Approach to Analyzing and Interpreting Tests for Practicing Clinicians
by John MeyersThis book presents detailed information on the Meyers Neuropsychological Battery (MNB) and the statistical system used to interpret the neuropsychological data patterns. By using the statistical methods a more consistent and appropriate interpretation can be made. This book contains information on normative data, performance validity, ecological validity, calculating strengths and weaknesses, comparison groups, and premorbid estimates as well as the statistical methods used with the MNB.The validity and reliability of the MNB as well as the ecological validity are all explained. Another area of detailed explanation is performance validity measures. This includes false positive rates as well as frequency of failures and passing rates for each individual performance validity measure. The statistical methods for group comparisons are demonstrated, which provides the reader with clear examples of how to apply the statistical methods to any test results. Answers are given for many of the questions asked about the MNB and the statistical methods. A modified Rohling's interpretive method is incorporated into the MNB, and demonstrates the benefit this model brings to data interpretation and practical application.This book will be an invaluable tool for clinical neuropsychologists, and all who assess and treat patients with cognitive impairment. The book is also for forensic neuropsychologists who wish to use an objective and consistent interpretive method, and lawyers and judges who wish to understand neuropsychological data and assessment.
The Mice Who Sing For Sex: And Other Weird Tales from the World of Science
by Lliana Bird Dr Jack LewisLliana Bird and Dr Jack Lewis tackle the strange and surreal phenomena from the depths of the oceans to the limits of the far flung universe; the dark corners of your laundry basket to the forgotten compartments of your fridge. Packed with unusual facts and stories of the absurd each of the fascinating insights is told with the Geek Chic team's inimitable humour and wit.An hilarious exploration all things bizarre from the world of science, The Mice Who Sing for Sex takes on weighty issues including heavy metal loving sharks, life-threatening skinny jeans, our impending jellyfish apocalypse and of course, the singing mice of the title.
The Mice Who Sing For Sex: And Other Weird Tales from the World of Science
by Jack Lewis Lliana BirdLliana Bird and Dr Jack Lewis tackle the strange and surreal phenomena from the depths of the oceans to the limits of the far flung universe; the dark corners of your laundry basket to the forgotten compartments of your fridge. Packed with unusual facts and stories of the absurd each of the fascinating insights is told with the Geek Chic team's inimitable humour and wit.An hilarious exploration all things bizarre from the world of science, The Mice Who Sing for Sex takes on weighty issues including heavy metal loving sharks, life-threatening skinny jeans, our impending jellyfish apocalypse and of course, the singing mice of the title.
The Micro World of Animal and Plant Cells (Micro Science)
by Precious McKenzieA tree and your pet look nothing alike, but they have one thing in common—they are both made up of cells. Cells are really small. You can see them only with a microscope. Young readers will find out about the parts of cells, how they work, and what the differences are between animal and plant cells.
The Micro World of Atoms and Molecules (Micro Science)
by Precious McKenzieWhat do all the things you can see and touch in the universe have in common? Atoms! Made up of electrons, protons, and neutrons, atoms are so tiny you can’t see them without special microscopes. Young readers will find out about the parts of atoms, how atoms join to form molecules, and their role in the periodic table of elements.
The Micro World of Dust Mites and Other Microscopic Creatures (Micro Science)
by Melissa MayerDid you know that there are animals all around you that you can’t see without a microscope? Sometimes it’s good you can’t see them. As you shed dead skin cells, thousands of dust mites gobble them up. Gross! Tiny water bears are super tough. They can survive in Earth’s coldest and hottest places and even in space! Young readers will learn amazing, weird, and sometimes gross facts about a variety of microscopic creatures.
The Micro World of Viruses and Bacteria (Micro Science)
by Melissa MayerThe world is full of tiny viruses and bacteria that can be seen only through a microscope. Some bacteria can be helpful, but others cause diseases such as typhoid fever. Viruses can cause deadly diseases such as COVID-19. Young readers will get all the facts about bacteria and viruses, including their similarities and differences, how they cause infections, and how people can keep dangerous germs from spreading.
The MicroRNA 2000 Transformer: Quantum Computing and Artificial Intelligence for Health
by Yoichi Robertus FujiiThe second edition includes new findings that were only a theory in the first edition, clarifying what is beginning to be proven true. All chapters have been updated, and new data on the analysis of major depressive disorder from exosome microRNA (miRNA) in plasma, traumatic brain injury, and Alzheimer's disease, brain glioma from cerebrospinal fluid miRNA, liver cancer, induced pluripotent stem (iPS) cell tumorigenesis, and other topics have been added. As predicted in the first edition, diseases can be predicted using the miRNA memory package (MMP) and miRNA entangling target sorting (METS), which could clarify the etiology of human diseases. Because researchers are investigating the relationship between circulating miRNAs and human diseases to develop new medicines, miRNA deep sequencing and detection methods will be high-speed and clever. The microRNA 2000 Transformer - Quantum Computing and Artificial Intelligence for Health is aimed at intermediate and advanced scientists, clinicians, students, and science enthusiasts. The Author hopes to lay the groundwork for future human health innovation.