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Very-high-energy Gamma-ray Observations of Pulsar Wind Nebulae and Cataclysmic Variable Stars with MAGIC and Development of Trigger Systems for IACTs

by Rubén López Coto

This thesis is a comprehensive work that addresses many of the open questions currently being discusssed in the very-high-energy (VHE) gamma-ray community. It presents a detailed description of the MAGIC telescope together with a glimpse of the future Cherenkov Telescope Array (CTA). One section is devoted to the design, development and characterization of trigger systems for current and future imaging atmospheric Cherenkov telescopes. The book also features a state-of-the-art description of pulsar wind nebula (PWN) systems, the study of the multi-TeV spectrum of the Crab nebula, as well as the discovery of VHE gamma rays at the multiwavelength PWN 3C 58, which were sought at these wavelengths for more than twenty years. It also includes the contextualization of this discovery amongst the current population of VHE gamma-ray PWNe. Cataclysmic variable stars represent a new source of gamma ray energies, and are also addressed here. In closing, the thesis reports on the systematic search for VHE gamma-ray emissions of AE Aquarii in a multiwavelength context and the search for VHE gamma-ray variability of novae during outbursts at different wavelengths.

The Very Idea of Modern Science

by Joseph Agassi

This book is a study of the scientific revolution as a movement of amateur science. It describes the ideology of the amateur scientific societies as the philosophy of the Enlightenment Movement and their social structure and the way they made modern science such a magnificent institution. It also shows what was missing in the scientific organization of science and why it gave way to professional science in stages. In particular the book studies the contributions of Sir Francis Bacon and of the Hon. Robert Boyle to the rise of modern science. The philosophy of induction is notoriously problematic, yet its great asset is that it expressed the view of the Enlightenment Movement about science. This explains the ambivalence that we still exhibit towards Sir Francis Bacon whose radicalism and vision of pure and applied science still a major aspect of the fabric of society. Finally, the book discusses Boyle's philosophy, his agreement with and dissent from Bacon and the way he single-handedly trained a crowd of poorly educated English aristocrats and rendered them into an army of able amateur researchers.

Very Massive Stars in the Local Universe

by Jorick S. Vink

This book presents the status of research on very massive stars in the Universe. While it has been claimed that stars with over 100 solar masses existed in the very early Universe, recent studies have also discussed the existence and deaths of stars up to 300 solar masses in the local Universe. This represents a paradigm shift for the stellar upper-mass limit, which may have major implications far beyond the field of stellar physics. The book comprises 7 chapters, which describe this discipline and provide sufficient background and introductory content for graduate (PhD) students and researchers from different branches of astronomy to be able to enter this exciting new field of very massive stars.

A (Very) Short History of Life on Earth: 4.6 Billion Years in 12 Pithy Chapters

by Henry Gee

In the tradition of Richard Dawkins, Bill Bryson, and Simon Winchester—An entertaining and uniquely informed narration of Life's life story.In the beginning, Earth was an inhospitably alien place—in constant chemical flux, covered with churning seas, crafting its landscape through incessant volcanic eruptions. Amid all this tumult and disaster, life began. The earliest living things were no more than membranes stretched across microscopic gaps in rocks, where boiling hot jets of mineral-rich water gushed out from cracks in the ocean floor.Although these membranes were leaky, the environment within them became different from the raging maelstrom beyond. These havens of order slowly refined the generation of energy, using it to form membrane-bound bubbles that were mostly-faithful copies of their parents—a foamy lather of soap-bubble cells standing as tiny clenched fists, defiant against the lifeless world. Life on this planet has continued in much the same way for millennia, adapting to literally every conceivable setback that living organisms could encounter and thriving, from these humblest beginnings to the thrilling and unlikely story of ourselves.In A (Very) Short History of Life on Earth, Henry Gee zips through the last 4.6 billion years with infectious enthusiasm and intellectual rigor. Drawing on the very latest scientific understanding and writing in a clear, accessible style, he tells an enlightening tale of survival and persistence that illuminates the delicate balance within which life has always existed.

Very Truly Yours, Nikola Tesla

by Nikola Tesla

Nikola Tesla was a man of letters. He wrote many letters to the editors of the magazines and newspapers of his day. These letters give a fascinating glimpse into the mind of an eccentric genius. Collected here for the first time are more than forty of Nikola Tesla's letters. The subject matter ranges widely, as Tesla was interested in almost everything. In these letters he responds to Marconi and Edison, gives his thoughts on the wars of his day, corrects inconsistencies in news reports, and much much more. Nikola Tesla has been called the most important man of the 20th Century. Without Tesla's ground-breaking work we'd all be sitting in the dark without even a radio to listen to.

Very, Very, Very Dreadful: The Influenza Pandemic of 1918

by Albert Marrin

From National Book Award finalist Albert Marrin comes a fascinating look at the history and science of the deadly 1918 flu pandemic--and the chances for another worldwide pandemic.In spring of 1918, World War I was underway, and troops at Fort Riley, Kansas, found themselves felled by influenza. By the summer of 1918, the second wave struck as a highly contagious and lethal epidemic and within weeks exploded into a pandemic, an illness that travels rapidly from one continent to another. It would impact the course of the war, and kill many millions more soldiers than warfare itself.Of all diseases, the 1918 flu was by far the worst that has ever afflicted humankind; not even the Black Death of the Middle Ages comes close in terms of the number of lives it took. No war, no natural disaster, no famine has claimed so many. In the space of eighteen months in 1918-1919, about 500 million people--one-third of the global population at the time--came down with influenza. The exact total of lives lost will never be known, but the best estimate is between 50 and 100 million. In this powerful book, filled with black and white photographs, nonfiction master Albert Marrin examines the history, science, and impact of this great scourge--and the possibility for another worldwide pandemic today.

Vesalius: The China Root Epistle

by Andreas Vesalius Daniel H. Garrison

This book provides the first annotated English translation from the original Latin of Andreas Vesalius' China Root Epistle. Ostensibly his appraisal of a fashionable herbal remedy, the China Root Epistle concentrates on Vesalius' skeptical appraisal of traditional Galenic anatomy, which was based on animal rather than human dissections. Along with reflections about his life as a young anatomist, Vesalius argued that the new science of anatomy should devote itself less to rhetorical polemics and more to the craft of direct observation based on human dissection. This volume provides annotations to link the Epistle with Vesalius' earlier and more famous On the Fabric of the Human Body, and includes illustrations from the famous woodcuts first used in the 1543 edition of the Fabrica.

Vesicle Trafficking in Cancer

by Gabi Tarcic Yosef Yarden

Endocytosis and vesicular trafficking determine the landscape of the cell's exterior, namely the density of surface molecules, such as receptors for growth factors and cytokines, adhesion molecules like integrins and cadherins, and a plethora of nutrient carriers. Hence, endocytosis is involved in signal transduction, cell adhesion and migration, as well as metabolism. To exploit these fundamental processes, malignancies subtly and multiply manipulate the endocytosis and the subsequent trafficking of protein cargoes. This is achieved by simultaneously altering the cytoskeleton, vesicle budding, cargo sorting and intracellular degradation. By highlighting the underlying molecular processes and concentrating on specific examples, this book reviews the recent emergence of derailed endocytosis and vesicular trafficking as a landmark of cancer. In-depth understanding of this common feature of tumors might lead the way to drug-induced strategies, able to rectify intracellular trafficking in cancer.

Vesper Flights

by Helen Macdonald

Animals don't exist in order to teach us things, but that is what they have always done, and most of what they teach us is what we think we know about ourselves. In this book, the author brings together a collection of her best loved essays, along with new pieces on topics ranging from nostalgia for a vanishing countryside to the tribulations of farming ostriches to her own private vespers while trying to fall asleep. Meditating on notions of captivity and freedom, immigration and flight, the author invites us into her most intimate experiences: observing the massive migration of songbirds from the top of the Empire State Building, watching tens of thousands of cranes in Hungary, seeking the last golden orioles in Suffolk's poplar forests. She writes with heart-tugging clarity about wild boar, swifts, mushroom hunting, migraines, the strangeness of birds' nests, and the unexpected guidance and comfort we find when watching wildlife.

Vesuvius: A Biography

by Alwyn Scarth

The volcano that has fascinated scientists, writers, and poets for two millenniaCapricious, vibrant, and volatile, Vesuvius has been and remains one of the world's most dangerous volcanoes. In its rage, it has destroyed whole cities and buried thousands alive. In its calm, its ashes have fertilized the soil, providing for the people who have lived in its shadows. For over two millennia, the dynamic presence of this volcano has fascinated scientists, artists, writers, and thinkers, and inspired religious fervor, Roman architecture, and Western literature. In Vesuvius, Alwyn Scarth draws from the latest research, classical and eyewitness accounts, and a diverse range of other sources to tell the riveting story of this spectacular natural phenomenon.Scarth follows Vesuvius across time, examining the volcano's destruction of Pompeii and Herculaneum in 79 A.D., its eruptions during the Counter-Reformation that were viewed as God's punishment of sinners, and the building of the world's first volcano observatory on Vesuvius in the 1840s. Scarth explores the volcano's current position overlooking a population of more than three million people and the complex attitudes maintained by the residents, at once reverent, protective, and fearful. He also considers the next major eruption of Vesuvius, which experts have indicated could be the most powerful since 1631. The longer Vesuvius remains dormant, the more violent its reawakening will be, and despite scientific advances for predicting when this might occur, more people are vulnerable than ever before.Exploring this celebrated wonder from scientific, historical, and cultural perspectives, Vesuvius provides a colorful portrait of a formidable force of nature.

Veterinarian (Cool Helping Careers)

by William David Thomas

Keeping animals healthy is no easy job. Unlike people, animals have different bodies. Besides dogs and cats, vets need to know how to treat diseases that affect all kinds of pets-from hamsters and ferrets to lizards and snakes! Some vets work in farming areas and care for larger animals, such as horses and cows. Others care for animals in zoos and animal parks. If you love animals, find out if a career as a vet or a vet tech is right for you!

Veterinäronkologie kompakt

by Robert Klopfleisch

Das Buch gibt einen umfassenden und prägnanten Überblick über die grundsätzlichen Mechanismen der Tumorentstehung, diskutiert die relevantesten Tumoren der Haustiere im Detail und adressiert die Herangehensweise an die Tumordiagnose und -therapie. Die Kapitel enthalten zahlreiche makroskopische, histologische und zytologische Abbildungen zum besseren Verständnis der vermittelten Inhalte und stellt deshalb eine praktische Alternative zur ausschweifenden Spezialliteratur dar.Die Onkologie spielt sowohl als Lehrgebiet im Tiermedizinstudium als auch im täglichen Praxisleben des Tierarztes eine zunehmend wichtige Rolle. Veterinäronkologie kompakt richtet sich deshalb als umfassendes und gleichzeitig aber kurz gefasstes Nachschlagwerk sowohl an Tiermedizinstudenten als auch an den klinisch tätigen Tierarzt, der als Nichtspezialist einen schnellen Überblick und die wichtigsten Fakten zu einer spezifischen Tumorart benötigt.

Veterinary Care of Farm Rabbits: A Complete Practice Guide to Rabbit Medicine and Production

by João Simões José M. Monteiro

This holistic guide brings rabbit production science and medicine together. It considers the full spectrum of commercial rabbit husbandry, including intensive, semi-intensive, and organic systems for meat, fur and leather. Drawn from an international authorship, the book addresses practical and fundamental topics. In comprehensive sections, readers will find easy-to-read chapters on:• rabbit breeds, anatomy essentials and lagomorph physiology• rabbit production with details on animal facilities and farm design, international trading, rabbit meat processing and biosafety, including a vivid appendix on meat inspection• rabbit herd and health management, considering latest findings in welfare and behavior, preventive medicine, antimicrobial resistance and demedication to necropsy and specimen collection• significant rabbit diseases, covering encephalitozoonosis cuniculi, rabbit enteropathies, and many more• complete veterinary treatment, supplemented by reference ranges and interpretation of hematological and biochemical valuesBesides an increasing keeping of pet rabbits, the animals are gaining interest for sustainable food production, leading to a rise in farming in various parts of the world. In this context, the present guide provides valuable contributions for consulting veterinarians and students, industry professionals, breeders and technicians, as well as for experts from the small and companion animal sector.The relevance of rabbit farming from the viewpoints of greenhouse gas reduction and sustainable use of ecological resources (use of local feed) also creates useful links for readers interested in the sustainable development goals SDG 2 (Zero Hunger) and SDG 12 (Responsible Consumption and Production).

Veterinary Clinical Epidemiology: From Patient to Population

by Ronald D. Smith

4* Doody's Review! Ideal for veterinary students, residents and clinicians, the fourth edition of this bestselling textbook has been fully updated in line with developments in research and teaching. The logical chapter progression reflects the stages in a clinical case work-up and how epidemiological concepts and methods contribute. This new edition provides guidelines for improving patient and population health outcomes, and detecting emerging diseases through systematic evaluation of patient encounters and electronic medical records incorporates new methodologies and concepts drawn from the recent veterinary practice literature updates chapter content including expanded coverage of risk, statistical and economic analyses, and surveillance for emerging diseases more than 60 examples of clinical research drawn from the international veterinary practice literature presented as structured abstracts; follow-up questions invite the reader to participate in the analysis of results online links to full text versions of more than half of structured abstracts and more than 40% of the book’s 174 literature citations updates the listing and review of public and private online resources, including guidelines for online literature searching and critical evaluation of clinical reports. Today’s veterinary curricula places greater emphasis on experiential/problem-based learning versus discipline-oriented instruction. This fourth edition is ideally suited to introduce epidemiologic concepts and methodologies to veterinary students in the context of the patient encounter, and should be of use at any point in the veterinary curriculum.

Veterinary Clinical Parasitology (7th edition)

by Anne M. Zajac Gary A. Conboy

Peacocks can carry Ascaridia eggs while ducks and wild birds carry another ascarid genus. Mites can fool you because they are laterally compressed like fleas. Designed for desk reference but suitable for quick reviews and clinical practice, this guide focuses on morphologic identification of parasites in domestic animals, featuring accurate and cost-effective means of diagnosing parasitic infections. With over 400 color photographs and a layout ideal for field work, this covers the fecal examination for diagnosis, including collection, storage, shipment, exam procedures, use of the microscope, techniques for evaluation in grazing animals, identification of adult worms, and parasites of domestic animals. It also covers detection of protozoan and Helmith parasites in the urinary, reproductive and integumentary systems and in the eye, detection of parasites in the blood, diagnosis of arthropod parasites such as lice, fleas, flies, mites and ticks, and parasites of fish. Annotation ©2006 Book News, Inc. , Portland, OR (booknews. com)

Veterinary Clinical Trials From Concept to Completion

by Nigel Dent Ramzan Visanji

Conceived and edited by Nigel Dent and Ramzan Visanji, Veterinary Clinical Trials form Concept to Completion is designed for both established practitioners and novices, offering alternative ways of conducting studies and ensuring that the studies are guided by Good Clinical Practices and are in compliance with regulations. Comprehensive in scope, i

Veterinary Forensic Medicine and Forensic Sciences

by Jason H. Byrd Patricia Norris Nancy Bradley-Siemens

While there are several recent books on this emerging field, Veterinary Forensic Medicine and Forensic Sciences sets the bar, covering all relevant aspects in a succinct, easy-to-read, comprehensive format designed to be taught in a single-semester course. Intended to be the premier textbook on veterinary forensic sciences, the book covers the application of veterinary forensic medicine to cases, including the medical perspective as well as law enforcement response, crime scene management, and evidence recovery issues. Coverage includes the scientific and legal principles for veterinary forensic evidence. This clearly delineates it from veterinary-only practices, since the forensic aspects present additional challenges that include evidence recovery and preservation, report writing, and maintaining an evidentiary chain of custody, all the way through expert witness testimony. Some emerging topics that are covered include DNA and genetic evidence, entomological evidence in support of veterinary forensics, animal fighting, situational deaths, including poisonings, domestic violence, and cruelty, sharp and blunt force trauma, gunshot and wound ballistics, sexual assault, nonhuman odontology and osteology, and more. Features Details a process for forensic science case management for humane law enforcement agencies Presents multiple chapters on specific types of trauma analysis in animals Provides developments on current trends in forensic entomology as applied to wildlife crime and minimum postmortem interval determinations Explores national and international considerations in combating organized animal fighting Offers DNA applications for wildlife crime and environmental monitoring Outlines current animal and environmental forensic toxicology legal casework This text offers a straightforward presentation of current practices and includes several real-world case examples throughout to illustrate concepts. Fully illustrated with more than 280 full-color images, Veterinary Forensic Medicine and Forensic Sciences provides the latest in advances and up-to-date field techniques, applicable for student instruction in the classroom and beyond.

Veterinary Forensic Pathology, Volume 1

by Jason W. Brooks

This richly illustrated two-volume book offers a comprehensive and essential reference guide for veterinary pathologists and clinical veterinarians interested in performing animal necropsies for forensic casework. It presents a broad range of animal crime cases, with particular focus on the post mortem examination and the observed pathology. This first volume introduces readers to veterinary forensics and the role of the veterinary pathologist in animal crime investigations. It guides them through the process of evidence collection and documentation, and covers the fundamentals of forensic necropsy and the estimation of time since death. In-depth descriptions of how to conduct the forensic evaluation of various traumatic injuries, firearm injuries, and asphyxia are also provided.

Veterinary Forensics: Investigation, Evidence Collection, and Expert Testimony

by Ernest Rogers Adam W. Stern

Veterinary Forensics: Investigation, Evidence Collection, and Expert Testimony will provide anyone involved in an investigation of an animal involved crime or civil action with the knowledge and tools that can give guidance for their actions in completing a forensic investigation. All 50 U.S. states, and numerous countries around the world, have laws against animal abuse and cruelty. Law enforcement agents, veterinarians, the judiciary, attorneys and forensic scientists may be involved in cases of animal cruelty, neglect or human crimes that may have an animal element. Additionally, the animal can be the victim, suspect or in some instances the witness of a crime. Given that acquittal or conviction is dependent upon the nature and veracity of the evidence, the quality of the evidence in an animal-related crime investigation must be beyond reproach. The book begins with a discussion of animal abuse and crimes against animals, crime scene investigation, and, from there, discusses various types of forensic examinations of the animal, culminating in a review of the judicial system and testimony in a court of law. All contributing authors are practicing professionals in law, veterinary medicine, and the private sector who provide current, best-practice evidence collection and forensic techniques. Chapters provide in-depth detail about the forensic clinical examination and forensic necropsy of small and large animal species, forensic radiology, forensic toxicology, bitemark analysis and animal behavior. Various, relevant forensic disciplines such as bloodstain pattern analysis, DNA analysis, animal sexual abuse, agroterrorism, animal hoarding, ritual crimes against animals, and animal fighting are discussed. Key Features: Presents established and accepted police techniques in animal crime scene investigation including identification, documentation and packaging of physical evidence and scene photography and videography Includes essential techniques to collect and preserve biological and DNA evidence for animal DNA testing Review of the forensic clinical examination and forensic necropsy of small and large animals Provides methods of evidence presentation in the courtroom, the nature of court room testimony, and the development of an expert report Veterinary Forensics: Investigation, Evidence Collection, and Expert Testimony fills the void of applied, real-world investigative techniques for the collection and presentation of veterinary forensic medical and scientific information. It will be a welcome reference to both the student and professional in the understanding all relevant evidentiary, investigative, and legal elements of the discipline.

Veterinary Medicines in the Environment

by Mark Crane Alistair B. A. Boxall Katie Barrett

Examine the Current State of the ScienceSurface water sampling programs across the globe have shown the presence of many different classes of medicines. The potential risks associated with the release of these medicines into the environment have become an increasingly important issue for environmental regulators. Effects of Veterinary Medicines in

Veterinary Molecular Immunology

by Shijun J. Zheng

This book focuses primarily on the newly discovered theory and techniques of veterinary molecular immunology. It also covers application of modern immunological methods into the treatment and control of infectious diseases and cancer, and future research trends. In terms of new immunological theories, this book focuses on recently-discovered innate lymphocytes (ILCs), signal transduction triggered by engagement of pattern recognition receptors (PRRs) with pathogen-associated molecular patterns (PAMPs), and signal communication between nerve and immune systems, antimicrobial peptides, immunoregulation and checkpoint, development and maturation of T and B lymphocytes, regulatory T cells, immune tolerance, and immunosuppression and evasion. In terms of new techniques and application, the book covers the categories and designs of preventive and therapeutic vaccines and the principle of developing vaccination program, occurrence, development and immune evasion of cancer cells, and the novel techniques for cancer therapy. In addition, comparison of avian and porcine cytokines with human and mouse ones is also provided in the appendices to illustrate the differences in cytokines between species. This book is valuable for the undergraduates, graduate students or professional researchers with requirement for advanced studies in veterinary immunology. It meets their requirements for improving and expanding knowledge of immunology.

Veterinary Psychiatry of the Dog: Diagnosis and Treatment of Behavioral Disorders

by Sylvia Masson Stéphane Bleuer-Elsner Gérard Muller Tiphaine Medam Jasmine Chevallier Emmanuel Gaultier

This richly illustrated textbook delivers a functional vision of dog behaviors. Daily applicable, it offers practical solutions for canine behavioral care with a consistently medical approach to disorders. Readers find a thorough introduction to factors influencing behavior, the canine neuroanatomy and physiology, psychopathologies, as well as treatment options. Drawing on the latest studies in neuroscience, ethology, psychology, and psychiatry, as well as the clinical experience of its expert authors, this guide is both comprehensive and accessible. Multiple clinical case studies illustrate and support presented details on medication and therapies.Behavioral pathology is one of the main challenges in veterinary medicine. Not only are they a cause of suffering for the animal, but they can also affect the quality of the relationship with the pet owners or pose a danger to society. Hence, treatment of these behavioral disorders requires an integrative approach to canine healthand well-being.The book's easy-to-access and descriptive structure allows many audiences to understand a subject area that is all too often considered complex. It addresses veterinary students, practitioners, and future expert veterinarians seeking approach to deep knowledge, as well as all other dog professionals curious to discover a complementary view with respect for the animal and owner.

Veterinary Science

by Alberto Gaiti Cristiano Boiti Antonio Pugliese

Today, veterinary science experiences major development in all its fields as a consequence of continuous technological advances in diagnostic tools and breakthrough in applied genomics and biology. This book contains 33 proceedings that were selected among those presented at the 64th Italian Veterinary Science Congress held at ASTI in 2010. It provides a timely overview of the current progress made by Italian researchers and would be of great value to anyone interested in the field of veterinary science, from animal health and care to food hygiene, and from basic to applied disciplines.

Veterinary Treatment for Working Equines

by Graham R Duncanson

There are an estimated 95 million equines working throughout the world, providing vital power and transport for many communities, especially in developing countries. Focusing on equines used to carry out working tasks such as pulling or carrying, as opposed to those used for riding or racing, this practical veterinary text details the specific treatment requirements to improve welfare of working horses, ponies, mules and donkeys. Chapters discuss diagnostic tests, equipment and medicines, anaesthesia, vaccines, nutrition, dentistry and ophthalmology, and all common conditions including those of heart, hoof and limb.

Veterinary Zootoxicology

by Murray E. Fowler

Only clinically oriented volume devoted to poisonous animals and venoms. Veterinary Zootoxicology provides an excellent overview of the state of the art in venom research. Clinical problems encountered in the United States are emphasized, but situations that occur in other areas of the world are examined as well. The book describes clinical syndromes caused by poisonous animals and provides facts, techniques, methodologies, and regimens designed to improve the clinical management of animals envenomated by other animals. Veterinary Zootoxicology is ideal for practicing veterinarians, students, instructors, wildlife biologists, and others who must know how to evaluate, diagnose, and treat envenomated animals.

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