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The Nature of the Mechanical Bond: From Molecules to Machines
by J. Fraser Stoddart Carson J. Bruns"The story is told by THE inventor-pioneer-master in the field and is accompanied by amazing illustrations... [it] will become an absolute reference and a best seller in chemistry!" Alberto Credi "... the great opus on the mechanical bond. A most impressive undertaking!" Jean-Marie Lehn Congratulations to co-author J. Fraser Stoddart, a 2016 Nobel Laureate in Chemistry. In molecules, the mechanical bond is not shared between atoms--it is a bond that arises when molecular entities become entangled in space. Just as supermolecules are held together by supramolecular interactions, mechanomolecules, such as catenanes and rotaxanes, are maintained by mechanical bonds. This emergent bond endows mechanomolecules with a whole suite of novel properties relating to both form and function. They hold unlimited promise for countless applications, ranging from their presence in molecular devices and electronics to their involvement in remarkably advanced functional materials. The Nature of the Mechanical Bond is a comprehensive review of much of the contemporary literature on the mechanical bond, accessible to newcomers and veterans alike. Topics covered include: Supramolecular, covalent, and statistical approaches to the formation of entanglements that underpin mechanical bonds in molecules and macromolecules Kinetically and thermodynamically controlled strategies for synthesizing mechanomolecules Chemical topology, molecular architectures, polymers, crystals, and materials with mechanical bonds The stereochemistry of the mechanical bond (mechanostereochemistry), including the novel types of dynamic and static isomerism and chirality that emerge in mechanomolecules Artificial molecular switches and machines based on the large-amplitude translational and rotational motions expressed by suitably designed catenanes and rotaxanes. This contemporary and highly interdisciplinary field is summarized in a visually appealing, image-driven format, with more than 800 illustrations covering both fundamental and applied research. The Nature of the Mechanical Bond is a must-read for everyone, from students to experienced researchers, with an interest in chemistry's latest and most non-canonical bond.Read the Preface
The Nature-Nurture Debates
by Dale GoldhaberHow is it possible that in more than one hundred years, the nature-nurture debate has not come to a satisfactory resolution? The problem, Dale Goldhaber argues, lies not with the proposed answers, but with the question itself. In The Nature-Nurture Debate, Goldhaber reviews the four major perspectives on the issue - behavior genetics, environment, evolutionary psychology and developmental systems theory - and shows that the classic, reductionist strategies (behavior genetics and environmental approaches) are incapable of resolving the issue because they each offer a false perspective on the process of human development. It is only through a synthesis of the two holistic perspectives of evolutionary psychology and developmental systems theory that we will be able to understand the nature of human behavior.
The Nature-Study Idea: And Related Writings (The Liberty Hyde Bailey Library)
by Liberty Hyde BaileyIn The Nature-Study Idea, Liberty Hyde Bailey articulated the essence of a social movement, led by ordinary public-school teachers, that lifted education out of the classroom and placed it into firsthand contact with the natural world. The aim was simple but revolutionary: sympathy with nature to increase the joy of living and foster stewardship of the earth.With this definitive edition, John Linstrom reintroduces The Nature-Study Idea as an environmental classic for our time. It provides historical context through a wealth of related writings, and introductory essays relate Bailey's vision to current work in education and the intersection of climate change and culture. In this period of planetary turmoil, Bailey's ambition to cultivate wonder (in adults as well as children) and lead readers back into the natural world is more important than ever.
The Navier-Stokes Problem in the 21st Century
by Pierre Gilles Lemarie-RieussetPraise for the first edition “The author is an outstanding expert in harmonic analysis who has made important contributions. The book contains rigorous proofs of a number of the latest results in the field. I strongly recommend the book to postgraduate students and researchers working on challenging problems of harmonic analysis and mathematical theory of Navier-Stokes equations." —Gregory Seregin, St Hildas College, Oxford University “"This is a great book on the mathematical aspects of the fundamental equations of hydrodynamics, the incompressible Navier-Stokes equations. It covers many important topics and recent results and gives the reader a very good idea about where the theory stands at present.” —Vladimir Sverak, University of Minnesota The complete resolution of the Navier–Stokes equation—one of the Clay Millennium Prize Problems—remains an important open challenge in partial differential equations (PDEs) research despite substantial studies on turbulence and three-dimensional fluids. The Navier–Stokes Problem in the 21st Century, Second Edition continues to provide a self-contained guide to the role of harmonic analysis in the PDEs of fluid mechanics, now revised to include fresh examples, theorems, results, and references that have become relevant since the first edition published in 2016.
The Navstar Global Positioning System
by Tom LogsdonThe Navstar Global Positioning System satellites are positioned in six orbital planes, 10,898 nautical miles from earth, enabling an unlimited number of users to receive passively their longitude, latitude, and altitude. With a minimum of math, the author explains how to use the system and provides a group of example applications. Four appendices offer additional sources of information, a list of user-set makers, navigation related clubs, and a list of navigation related magazines and periodicals.
The Neanderthal's Necklace: In Search of the First Thinkers
by Juan Luis Arsuaga Andy KlattThe Neanderthals provide a surprising mirror for modern-day humanity. They belonged to our evolutionary group and lived like the Cro-Magnons, our ancestors, did - worshipping, socializing, and hunting. The struggle between Neanderthals and Cro-Magnons lasted thousands of years. The Cro-Magnons were not biologically fit for extreme cold weather, but their ingenuity allowed them to settle down, band together, and survive. In this tale of life, death, and the awakening of human awareness, Juan Luis Arsuaga, Spain's most celebrated paleoanthropologist, depicts the dramatic struggle between two clashing species, of which only one survives.
The Near-Surface Layer of the Ocean
by Alexander Soloviev Roger LukasThe rationale for publishing a second edition of this monograph is that this area of research continues to show remarkable advancement. The new generation of synthetic aperture radar satellites has provided unprecedented spatial resolution of sea surface features. In addition, satellites to measure sea surface salinity have been launched. Computational fluid dynamics models open new opportunities in understanding the processes in the near-surface layer of the ocean and their visibility from space. Passive acoustic methods for monitoring short surface waves have significantly progressed. Of importance for climate research, processes in the near-surface layer of the ocean contribute to errors in satellite estimates of sea surface temperature trends. Due to growing applications of near-surface science, it is anticipated that more students will be trained in this area of research. Therefore this second edition of the monograph is closer to a textbook format.
The Neck: A Natural and Cultural History
by Kent DunlapA 300-million-year tour of the prominent role of the neck in animal evolution and human culture. Humans give a lot of attention to the neck. We decorate it with jewelry and ties, kiss it passionately, and use it to express ourselves in word and song. Yet, at the neck, people have also shackled their prisoners, executed their opponents, and slain their victims. Beyond the drama of human culture, animals have evolved their necks into a staggering variety of shapes and uses vital to their lifestyles. The Neck delves into evolutionary time to solve a living paradox—why is our neck so central to our survival and culture, but so vulnerable to injury and disease? Biologist Kent Dunlap shows how the neck's vulnerability is not simply an unfortunate quirk of evolution. Its weaknesses are intimately connected to the vessels, pipes, and glands that make it so vital to existence. Fun and far-reaching, The Neck explores the diversity of forms and functions of the neck in humans and other animals and shows how this small anatomical transition zone has been a locus of incredible evolutionary and cultural creativity.
The Need for Critical Thinking and the Scientific Method
by Finlay MacRitchieThe book exposes many of the misunderstandings about the scientific method and its application to critical thinking. It argues for a better understanding of the scientific method and for nurturing critical thinking in the community. <P><P>This knowledge helps the reader to analyze issues more objectively, and warns about the dangers of bias and propaganda. The principles are illustrated by considering several issues that are currently being debated. These include anthropogenic global warming (often loosely referred to as climate change), dangers to preservation of the Great Barrier Reef, and the expansion of the gluten-free food market and genetic engineering.
The Neem Genome (Compendium of Plant Genomes)
by Chittaranjan Kole Malali Gowda Ambardar SheetalThis book describes the sequencing efforts for Neem (Azadirachta indica A. Juss), one of the most versatile tropical evergreen tree species. The neem tree is a source of various natural products, including the potent biopesticide azadirachtin and limonoids, which have a broad spectrum of activity against insect pests and microbial pathogens. To identify genes and pathways in neem, three neem genomes and several transcriptomes are studied using next-generation sequencing technologies.Neem has been extensively used in Ayurveda, Unani and homoeopathic medicine and is often referred to as the ‘village pharmacy’ by natives due to its wealth of medicinal properties.Besides the description of the genome, this book discusses the neem microbiome and its role in the production of neem metabolites like salanin, nimbin and exopy-azadirachtin under in vitro conditions. It also highlights cell and tissue culture using various neem explants including the leaf, root, shoot, cambium, etc.
The Negro Church In America/The Black Church Since Frazier
by C. Eric Lincoln E. Franklin FrazierFrazier's study of the black church and an essay by Lincoln arguing that the civil rights movement saw the splintering of the traditional black church and the creation of new roles for religion.
The Neighborhood Project: Using Evolution to Improve My City, One Block at a Time
by David Sloan WilsonAfter decades studying creatures great and small, evolutionary biologist David Sloan Wilson had an epiphany: Darwin's theory won't fully prove itself until it improves the quality of human life in a practical sense. And what better place to begin than his hometown of Binghamton, New York? Making a difference in his own city would provide a model for cities everywhere, which have become the habitat for over half of the people on earth. Inspired to become an agent of change, Wilson descended on Binghamton with a scientist's eye and looked at its toughest questions, such as how to empower neighborhoods and how best to teach our children. He combined the latest research methods from experimental economics with studies of holiday decorations and garage sales. Drawing upon examples from nature as diverse as water striders, wasps, and crows, Wilson's scientific odyssey took him around the world, from a cave in southern Africa that preserved the dawn of human culture to the Vatican in Rome. Along the way, he spoke with dozens of fellow scientists, whose stories he relates along with his own.Wilson's remarkable findings help us to understand how we must become wise managers of evolutionary processes to accomplish positive change at all scales, from effective therapies for individuals, to empowering neighborhoods, to regulating the worldwide economy. With an ambitious scope that spans biology, sociology, religion, and economics, The Neighborhood Project is a memoir, a practical handbook for improving the quality of life, and an exploration of the big questions long pondered by religious sages, philosophers, and storytellers. Approaching the same questions from an evolutionary perspective shows, as never before, how places define us.
The Neotoma Paleoecology Database: A Research Outreach Nexus (Elements of Paleontology)
by Simon James Goring Russell Graham Shane Loeffler Amy Myrbo James S. Oliver Carol Ormond John W. WilliamsPaleoecological data from the Quaternary Period (2.6 million years ago to present) provides an opportunity for educational outreach for the earth and biological sciences. Paleoecology data repositories serve as technical hubs and focal points within their disciplinary communities and so are uniquely situated to help produce teaching modules and engagement resources. The Neotoma Paleoecology Database provides support to educators from primary schools to graduate students. In collaboration with pedagogical experts, the Neotoma Paleoecology Database team has developed teaching modules and model workflows. Early education is centered on discovery; higher-level educational tools focus on illustrating best practices for technical tasks. Collaborations among pedagogic experts, technical experts and data stewards, centered around data resources such as Neotoma, provide an important role within research communities, and an important service to society, supporting best practices, translating current research advances to interested audiences, and communicating the importance of individual research disciplines.
The Nervous System
by Helen FrostSimple text, photographs, and diagrams introduce the nervous system and its purpose, parts, and functions.
The Nervous System (A True Book)
by Christine Taylor-ButlerDid you know that your nerve impulses are 1,000 times SLOWER than your computer? Or that it's normal to fart - as often as 20 times a day? Get the buzz on health and the human body with this fun and fascinating series.
The Nesting Season: Cuckoos, Cuckolds, and the Invention of Monogamy
by Bernd HeinrichWhy are the eggs of the marsh wren deep brown, the winter wren's nearly white, and the gray catbird's a brilliant blue? And what in the DNA of a penduline tit makes the male weave a domed nest of fibers and the female line it with feathers, while the bird-of-paradise male builds no nest at all, and his bower-bird counterpart constructs an elaborate dwelling? These are typical questions that Bernd Heinrich pursues in the engaging style we've come to expect from him supplemented here with his own stunning photographs and original watercolors. One of the world's great naturalists and nature writers, Heinrich shows us how the sensual beauty of birds can open our eyes to a hidden evolutionary process. Nesting, as Heinrich explores it here, encompasses what fascinates us most about birds from their delightful songs and spectacular displays to their varied eggs and colorful plumage; from their sex roles and mating rituals to nest parasitism, infanticide, and predation. What moves birds to mate and parent their young in so many different ways is what interests Heinrich and his insights into the nesting behavior of birds has more than a little to say about our own.
The Network of Life: A New View of Evolution
by David P. MindellWhy evolution is like a network, not a family tree—and why it matters for understanding the health of all living thingsIn The Network of Life, David Mindell explains why the conventional narrative of evolution needs to evolve. Ever since Darwin, evolution has largely been thought to work like a family tree in which species are related through a series of branching events. But, today, a growing knowledge of the ways species share genetic materials in a process known as horizontal evolution has revealed that evolution is actually a network of shared genealogy in which species are more interconnected than previously thought. In this book, Mindell presents this new narrative of life&’s evolution and its profound implications for all life on Earth.The Network of Life describes the drivers of horizontal evolution—interbreeding and genetic recombination, the merger of species, horizontal gene transfer, and coevolution. The network view of evolution that emerges supports a new symbiotic theory of health, which holds that the future health of humans, other species, and our shared environments depends on evolution and adaptation across life&’s network.Difficult times lie ahead for many of Earth&’s species as climates and habitats transform. At the same time, new and altered life-forms are arising and spreading in association with human activities. We are also learning to reshape and create life by mimicking the mechanisms of horizontal evolution, and we are coevolving with technology as we enhance our bodies, brains, and life spans. The Network of Life shows why and how increasing our knowledge of horizontal evolution can provide critical lessons as we navigate our looming challenges.
The Networking of Chaperones by Co-Chaperones (Subcellular Biochemistry #101)
by Gregory L. Blatch Adrienne L. EdkinsCo-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is the dynamic integration of the processes of protein folding, degradation and translocation to ensure that cellular function is finely tuned in space and time. This third edition of the book The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by co-chaperones, a diverse cohort of non-client proteins. Since the second edition was released, not only has knowledge deepened on how co-chaperones act as nodes to network and functionalise chaperones, but an understanding of their broader biological function has started to emerge. The third edition provides new and updated chapters highlighting recent developments and emerging themes on co-chaperones, such as their extracellular functions, their role in human disease and their status as putative drug targets. The book is a useful resource for both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology.
The Networking of Chaperones by Co-chaperones
by Gregory Lloyd Blatch Adrienne Lesley EdkinsCo-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is a dynamic balance between the integrated processes of protein folding, degradation and translocation. The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by a cohort of diverse non-client proteins, known as co-chaperones. The second edition includes the current status of the field and descriptions of a number of novel co-chaperones that have been recently identified. This new edition has a strong focus on the role of co-chaperones in human disease and as putative drug targets. The book will be a resource for both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology.
The Neural Architecture of Grammar
by Stephen E. NadeauLinguists have mapped the topography of language behavior in many languages in intricate detail. To understand how the brain supports language function, however, we must take into account the principles and regularities of neural function. Mechanisms of neurolinguistic function cannot be inferred solely from observations of normal and impaired language. In The Neural Architecture of Grammar, Stephen Nadeau develops a neurologically plausible theory of grammatic function. He brings together principles of neuroanatomy, neurophysiology, and parallel distributed processing and draws on literature on language function from cognitive psychology, cognitive neuropsychology, psycholinguistics, and functional imaging to develop a comprehensive neurally based theory of language function. Nadeau reviews the aphasia literature, including cross-linguistic aphasia research, to test the model's ability to account for the findings of these empirical studies. Nadeau finds that the model readily accounts for a crucial finding in cross-linguistic studies--that the most powerful determinant of patterns of language breakdown in aphasia is the predisorder language spoken by the subject--and that it does so by conceptualizing grammatic function in terms of the statistical regularities of particular languages that are encoded in network connectivity. He shows that the model provides a surprisingly good account for many findings and offers solutions for a number of controversial problems. Moreover, aphasia studies provide the basis for elaborating the model in interesting and important ways.
The Neural Architecture of Grammar (The\mit Press Ser.)
by Stephen E. NadeauA comprehensive, neurally based theory of language function that draws on principles of neuroanatomy, cognitive psychology, cognitive neuropsychology, psycholinguistics, and parallel distributed processing.Linguists have mapped the topography of language behavior in many languages in intricate detail. To understand how the brain supports language function, however, we must take into account the principles and regularities of neural function. Mechanisms of neurolinguistic function cannot be inferred solely from observations of normal and impaired language. In The Neural Architecture of Grammar, Stephen Nadeau develops a neurologically plausible theory of grammatic function. He brings together principles of neuroanatomy, neurophysiology, and parallel distributed processing and draws on literature on language function from cognitive psychology, cognitive neuropsychology, psycholinguistics, and functional imaging to develop a comprehensive neurally based theory of language function. Nadeau reviews the aphasia literature, including cross-linguistic aphasia research, to test the model's ability to account for the findings of these empirical studies. Nadeau finds that the model readily accounts for a crucial finding in cross-linguistic studies—that the most powerful determinant of patterns of language breakdown in aphasia is the predisorder language spoken by the subject—and that it does so by conceptualizing grammatic function in terms of the statistical regularities of particular languages that are encoded in network connectivity. He shows that the model provides a surprisingly good account for many findings and offers solutions for a number of controversial problems. Moreover, aphasia studies provide the basis for elaborating the model in interesting and important ways.
The Neural Bases of Multisensory Processes (Frontiers in Neuroscience)
by Mark T. Wallace Micah M. MurrayIt has become accepted in the neuroscience community that perception and performance are quintessentially multisensory by nature. Using the full palette of modern brain imaging and neuroscience methods, The Neural Bases of Multisensory Processes details current understanding in the neural bases for these phenomena as studied across species, stages
The Neural Basis of Free Will
by Peter Ulric TseThe issues of mental causation, consciousness, and free will have vexed philosophers since Plato. In this book, Peter Tse examines these unresolved issues from a neuroscientific perspective. In contrast with philosophers who use logic rather than data to argue whether mental causation or consciousness can exist given unproven first assumptions, Tse proposes that we instead listen to what neurons have to say. Because the brain must already embody a solution to the mind--body problem, why not focus on how the brain actually realizes mental causation? Tse draws on exciting recent neuroscientific data concerning how informational causation is realized in physical causation at the level of NMDA receptors, synapses, dendrites, neurons, and neuronal circuits. He argues that a particular kind of strong free will and "downward" mental causation are realized in rapid synaptic plasticity. Recent neurophysiological breakthroughs reveal that neurons function as criterial assessors of their inputs, which then change the criteria that will make other neurons fire in the future. Such informational causation cannot change the physical basis of information realized in the present, but it can change the physical basis of information that may be realized in the immediate future. This gets around the standard argument against free will centered on the impossibility of self-causation. Tse explores the ways that mental causation and qualia might be realized in this kind of neuronal and associated information-processing architecture, and considers the psychological and philosophical implications of having such an architecture realized in our brains.
The Neural Basis of Free Will: Criterial Causation
by Peter Ulric TseA neuroscientific perspective on the mind–body problem that focuses on how the brain actually accomplishes mental causation. The issues of mental causation, consciousness, and free will have vexed philosophers since Plato. In this book, Peter Tse examines these unresolved issues from a neuroscientific perspective. In contrast with philosophers who use logic rather than data to argue whether mental causation or consciousness can exist given unproven first assumptions, Tse proposes that we instead listen to what neurons have to say. Tse draws on exciting recent neuroscientific data concerning how informational causation is realized in physical causation at the level of NMDA receptors, synapses, dendrites, neurons, and neuronal circuits. He argues that a particular kind of strong free will and “downward” mental causation are realized in rapid synaptic plasticity. Such informational causation cannot change the physical basis of information realized in the present, but it can change the physical basis of information that may be realized in the immediate future. This gets around the standard argument against free will centered on the impossibility of self-causation. Tse explores the ways that mental causation and qualia might be realized in this kind of neuronal and associated information-processing architecture, and considers the psychological and philosophical implications of having such an architecture realized in our brains.
The Neural Code of Pitch and Harmony
by Langner, Gerald and Benson, Christina Gerald Langner Christina BensonHarmony is an integral part of our auditory environment. Resonances characterised by harmonic frequency relationships are found throughout the natural world and harmonic sounds are essential elements of speech, communication and, of course, music. Providing neurophysiological data and theories that are suitable to explain the neural code of pitch and harmony, the author demonstrates that musical pitch is a temporal phenomenon and musical harmony is a mathematical necessity based on neuronal mechanisms. Moreover, he offers new evidence for the role of an auditory time constant for speech and music perception as well as for similar neuronal processing mechanisms of auditory and brain waves. Successfully relating current neurophysiological results to the ancient ideas of Pythagoras, this unique title will appeal to specialists in the fields of neurophysiology, neuroacoustics, linguistics, behavioural biology and musicology as well as to a broader audience interested in the neural basis of music perception.